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Journal of Nutrition, Health & Aging

A Martín, O Ortega, M Roca, M Arús, P Clavé
BACKGROUND: Oropharyngeal dysphagia (OD) is a newly defined geriatric syndrome that causes nutritional and respiratory complications in older hospitalized patients. Following hospital discharge, OD also causes hospital readmission and mortality in this population. OBJECTIVE: Our aim was to assess the effect of a minimal-massive intervention (MMI) in reducing nutritional and respiratory complications in older hospitalized patients with OD. DESIGN AND PARTICIPANTS: An open label trial was performed on 186 hospitalized older patients (>70y) with OD; 62 of these patients with OD were treated with the MMI and paired by sex, age, functionality, comorbidities and body mass index with two controls...
2018: Journal of Nutrition, Health & Aging
W Ren, J Wu, L Li, Y Lu, Y Shao, Y Qi, B Xu, Y He, Y Hu
Glucagon-like peptide-2 (GLP-2) plays a major role in repairing impaired intestinal mucosa, but its mechanism in the improvement of intestinal barrier function during the aging process remains unclear. In this study, 26-month-old male Sprague-Dawley rats were randomized to control group and GLP-2 group treated with a dose of 250 μg•kg-1•d-1 by intraperitoneal injection. After 14 days of treatment, intestinal mucosal morphometric changes were observed by light microscopy and transmission electron microscopy (TEM)...
2018: Journal of Nutrition, Health & Aging
A R Osella, N Veronese, M Notarnicola, A M Cisternino, G Misciagna, V Guerra, A Nitti, A Campanella, M G Caruso
OBJECTIVE: The consumption of potatoes is increasing worldwide, but few studies have assessed the association between potato consumption and mortality, particularly in Mediterranean countries. We therefore investigated whether potato consumption is associated with higher risk of death in a large cohort of people living in South Italy. DESIGN: Longitudinal. SETTING: Community-dwelling. MEASUREMENTS: 2,442 participants coming from MICOL and NUTRIHEP studies aged more than 50 years at baseline were followed-up for 11 years...
2018: Journal of Nutrition, Health & Aging
M Haution-Bitker, T Gilbert, A Vignoles, C Lecardonnel, S Watelet, E Blond, J Drai, M Bonnefoy
OBJECTIVE: To examine the association of plasmatic and erythrocyte concentrations polyunsaturated fatty acids (PUFA) with both cognitive status and decline. DESIGN: Longitudinal observational cohort study. SETTING: Memory Clinic of Lyon Sud university hospital. PARTICIPANTS: 140 patients, aged 60 and older, were referred to the memory clinic, and successively included in the cohort, between March 2010 and February 2014...
2018: Journal of Nutrition, Health & Aging
Y Yu, Y Zhao, F Teng, J Li, Y Guan, J Xu, X Lv, F Guan, M Zhang, L Chen
OBJECTIVE: The manifestations of aging include cognitive deficits and muscular dysfunction, which are closely linked to impairment of mitochondrial biogenesis. Berberine, an isoquinoline alkaloid, presents multiple anti-diabetic pharmacological effects. Evidence has indicated that insulin resistance and cognitive impairment share the same pathogenesis, and berberine could reverse glucose metabolism abnormalities and muscle mitochondrial dysfunction induced by a high-fat diet. This study was used to investigate whether berberine could be used as an anti-aging drug to prevent cognitive deficits and muscular dysfunction in natural aging...
2018: Journal of Nutrition, Health & Aging
M Fanelli Kuczmarski, R T Pohlig, E Stave Shupe, A B Zonderman, M K Evans
OBJECTIVE: To determine the association of handgrip strength (HS) with protein intake, diet quality, and nutritional and cardiovascular biomarkers in African American and White adults. DESIGN: Cross-sectional wave 3 (2009-2013) of the cohort Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study. PARTICIPANTS: Socioeconomically diverse urban population of 2,468 persons aged 33 to 71 years. MEASUREMENTS: Socio-demographic correlates, dietary intakes and biomarkers, HS, physical performance measures were collected...
2018: Journal of Nutrition, Health & Aging
N Otaki, N Tanino, M Yokoro, M Yano, M Akita, H Uemura, M Maeda, K Fukuo
OBJECTIVES: The purpose of this study was to assess the relationship between economic security and self-rated health for elderly Japanese residents living alone. DESIGN: A secondary analysis of a cross-sectional study. SETTING: N City, H. Prefecture, Japan. PARTICIPANTS: Survey questionnaires were distributed to 2,985 elderly residents living alone, aged ≥70 years, of which, 1,939 (65.0%) were returned and treated as valid responses...
2018: Journal of Nutrition, Health & Aging
A Hajek, C Brettschneider, H van den Bussche, H Kaduszkiewicz, A Oey, B Wiese, S Weyerer, J Werle, A Fuchs, M Pentzek, J Stein, T Luck, H Bickel, E Mösch, K Heser, M Bleckwenn, M Scherer, S G Riedel-Heller, W Maier, H-H König
OBJECTIVES: The aim of this study was to identify determinants of outpatient health care utilization among the oldest old in Germany longitudinally. DESIGN: Multicenter prospective cohort "Study on Needs, health service use, costs and health-related quality of life in a large sample of oldest-old primary care patients (85+)" (AgeQualiDe). SETTING: Individuals in very old age were recruited via GP offices at six study centers in Germany...
2018: Journal of Nutrition, Health & Aging
B Fougère, J E Morley, M O Little, P De Souto Barreto, M Cesari, B Vellas
As the population ages, the number of older people with frailty is expected to increase worldwide with consequent rising of expenditures for healthcare and long-term care. Effective methods for preventing or delaying the onset of disability are urgently required. Frailty is a common and important geriatric condition characterized by age-associated declines in multiple physiological mechanisms, leading to increased vulnerability to stressors and higher risk for adverse health outcomes. Significant advancements have been made in the understanding of the frailty pathophysiological background...
2018: Journal of Nutrition, Health & Aging
A Sanz-Paris, M Camprubi-Robles, J M Lopez-Pedrosa, S L Pereira, R Rueda, M D Ballesteros-Pomar, J M Garcia Almeida, A J Cruz-Jentoft
Aging and disease-related malnutrition are well associated with loss of muscle mass and function. Muscle mass loss may lead to increased health complications and associated increase in health care costs, especially in hospitalized individuals. High protein oral nutritional supplements enriched with β-hydroxy-β-methylbutyrate (HP-ONS+HMB) have been suggested to provide benefits such as improving body composition, maintaining muscle mass and function and even decreasing mortality rates. The present review aimed to examine current evidence on the effect of HP-ONS+HMB on muscle-related clinical outcomes both in community and peri-hospitalization patients...
2018: Journal of Nutrition, Health & Aging
R Silva, N Pizato, F da Mata, A Figueiredo, M Ito, M G Pereira
BACKGROUND: Population aging is increasing and this process together with its characteristics influence the prevalence and incidence of chronic conditions and musculoskeletal-functional outcomes such as frailty, functional disability and sarcopenia. Nutritional strategies focused on dietary patterns, such as a Mediterranean diet, can be protective from these outcomes. PURPOSE: To investigate the association between adherence to a Mediterranean diet and frailty, functional disability and sarcopenia in community-dwelling older people...
2018: Journal of Nutrition, Health & Aging
N J Bishop, K E Zuniga, A L Lucht
OBJECTIVES: Our first objective was to estimate empirically-derived subgroups (latent profiles) of observed carbohydrate, protein, and fat intake density in a nationally representative sample of older U.S. adults. Our second objective was to determine whether membership in these groups was associated with levels of, and short term change in, physical mobility limitations. DESIGN AND SETTING: Measures of macronutrient density were taken from the 2013 Health Care and Nutrition Study, an off-year supplement to the Health and Retirement Study, which provided indicators of physical mobility limitations and sociodemographic and health-related covariates...
2018: Journal of Nutrition, Health & Aging
F van den Bos, M H Emmelot-Vonk, H J Verhaar, Y T van der Schouw
BACKGROUND: Although the incidences of osteoporosis and atherosclerosis increase with age, there is growing evidence that the coincidental occurrence of both diseases may be independent of age. In general, studies in men are scarce and results are inconsistent. OBJECTIVE: to investigate the relationship between atherosclerosis and bone mineral density, and the influence of insulin sensitivity and low grade inflammation on this relationship in 332 men without CVD...
2018: Journal of Nutrition, Health & Aging
R Backhaus, H C Beerens, E van Rossum, H Verbeek, J P H Hamers
No abstract text is available yet for this article.
2018: Journal of Nutrition, Health & Aging
J E Morley, M Berg-Weger, J Lundy
No abstract text is available yet for this article.
2018: Journal of Nutrition, Health & Aging
K H Pitkälä, F C Martin, S Maggi, S K Jyväkorpi, T E Strandberg
OBJECTIVES: The aim of this article is to describe the current status of geriatrics and position of geriatricians in 22 countries of three continents, and to portray their attitudes towards and resources allocated to geriatrics. METHODS: An electronic survey was delivered to a convenience sample of 22 geriatricians in leading positions of their countries. RESULTS: The time required in post graduation specialist training to become a geriatrician varied from one year (subspecialty in the USA) to six years (independent specialty in Belgium)...
2018: Journal of Nutrition, Health & Aging
J Woo, B W M Yu, R S M Chan, J Leung
OBJECTIVE: To examine the influence of various dietary patterns on ankle-brachial index (ABI) as a surrogate of atherosclerosis, taking into account serum levels of C-reactive protein (CRP) and factors that predispose to inflammation and/or endothelial damage (homocysteine) or may be protective (tryptophan, vitamin D), as well as age, gender, and lifestyle risk factors. DESIGN: Cross sectional analysis. SETTING: Cohort of 4000 men and women aged 65 years living in the community in Hong Kong SAR China...
2018: Journal of Nutrition, Health & Aging
Y Wang, Q Hao, L Su, Y Liu, S Liu, B Dong
BACKGROUND: Frailty is a common geriatric syndrome in old people. It remains controversial whether Mediterranean diet could prevent old people from developing into frailty. The aim of this study is to summarize the relevant studies and assess the effectiveness of adherence to Mediterranean diet on frailty in old people. METHOD: A systematic search of MEDLINE, EMBASE and Cochrane Central Register of Controlled Trials was conducted to identify all relevant studies up to Oct 2017...
2018: Journal of Nutrition, Health & Aging
S Giovannini, G Onder, F Lattanzio, S Bustacchini, G Di Stefano, R Moresi, A Russo, R Bernabei, F Landi
BACKGROUND: Selenium has a wide range of pleiotropic effects, influencing redox homeostasis, thyroid hormone metabolism, and protecting from oxidative stress and inflammation. Serum selenium levels are reduced in the older population. OBJECTIVES: to investigate the association of serum selenium levels with all-cause mortality in a sample of community-dwelling older adults. DESIGN AND SETTING: Data are from the 'Invecchiamento e Longevità nel Sirente' (Aging and Longevity in the Sirente geographic area, ilSIRENTE) study, a prospective cohort study that collected information on individuals aged 80 years and older living in an Italian mountain community (n=347)...
2018: Journal of Nutrition, Health & Aging
C E Graf, F R Herrmann, L Genton
BACKGROUND: A low phase angle (PA) has been associated with negative outcome in specific diseases. However, many patients suffer from several co-morbidities. This study aims at identifying the impact of the type and the severity of diseases on PA in a retrospective cohort study of older people. METHODS: We included all people ≥65 years who underwent a PA measurement (Nutriguard®) between 1990 and 2011 at the Geneva University Hospitals. PA was standardized for gender, age and body mass index according to German reference values...
2018: Journal of Nutrition, Health & Aging
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