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Epilepsy & Behavior: E&B

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https://www.readbyqxmd.com/read/29463469/lay-epilepsy-organizations-the-key-for-research-funding
#1
EDITORIAL
Janet Mifsud, Martin J Brodie, Ann Little
No abstract text is available yet for this article.
February 18, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29463468/leaving-some-myths-about-neurocysticercosis-and-epilepsy
#2
LETTER
J F Tellez-Zenteno, L Hernandez-Ronquillo
No abstract text is available yet for this article.
February 18, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29462779/effects-of-vagus-nerve-stimulation-on-heart-rate-variability-in-children-with-epilepsy
#3
Tugba Hirfanoglu, Ayse Serdaroglu, Ilker Cetin, Gokhan Kurt, Irem Y Capraz, Filiz Ekici, Ebru Arhan, Erhan Bilir
PURPOSE: The aim of this study was to evaluate the effects of vagus nerve stimulation (VNS) on heart rate variability (HRV) in children with epilepsy. METHODS: The subgroups of HRV, namely time domain (Standard deviation of NN interval (SDNN), SDNN index, Standard deviation of the averages of NN intervals (SDANN), Root mean square of successive differences (RMMSD), Adjacent NN intervals differing by more than 50 ms in the entire recording divided by the total number of all NN intervals (PNN50), triangular index) and frequency domain (Low-frequency (LF), High-frequency (HF), LF/HF), were investigated in 20 pediatric patients before and after 6 and 12months of VNS treatment during day and night by comparing their data with those of 20 control subjects...
February 17, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29459252/multimodal-noninvasive-seizure-network-mapping-software-a-novel-tool-for-preoperative-epilepsy-evaluation
#4
Elliot G Neal, Stephanie Maciver, Fernando L Vale
BACKGROUND: Despite rigorous preoperative evaluation, epilepsy surgery achieves seizure freedom in only two-thirds of cases. Current preoperative evaluation does not include a detailed network analysis despite the association of network-level changes with epilepsy. OBJECTIVE: We sought to create a software algorithm to map individualized epilepsy networks by combining noninvasive electroencephalography (EEG) source localization and nonconcurrent resting state functional magnetic resonance imaging (rsfMRI)...
February 17, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29459168/predictors-of-outcomes-and-refractoriness-in-status-epilepticus-a-prospective-study
#5
LETTER
Murat Mert Atmaca, Candan Gürses
No abstract text is available yet for this article.
February 16, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29455082/evaluating-subjective-cognitive-impairment-in-the-adult-epilepsy-clinic-effects-of-depression-number-of-antiepileptic-medications-and-seizure-frequency
#6
Lauren Feldman, Brittany Lapin, Robyn M Busch, Jocelyn F Bautista
OBJECTIVE: Subjective cognitive complaints are a frequent concern of patients with epilepsy. The Aldenkamp-Baker Neuropsychological Assessment Schedule (ABNAS) is a patient-reported scale validated to measure adverse cognitive effects of antiepileptic drugs (AEDs). The goals of this study were to identify predictors of patient-reported cognitive dysfunction and to assess the relationship between subjective and objective cognitive impairment. METHODS: The Cleveland Clinic Knowledge Program Data Registry was used to identify adult patients seen in outpatient epilepsy clinic from January to May 2015 and who completed the following scales: ABNAS for subjective cognitive impairment, Patient Health Questionnaire (PHQ-9) for depression, Generalized Anxiety Disorder 7-item (GAD-7) scale, Quality of Life in Epilepsy (QOLIE-10), and EuroQOL five dimensions questionnaire (EQ-5D) for health-related quality of life...
February 15, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29455081/quality-of-life-and-level-of-burden-in-primary-caregivers-of-patients-with-epilepsy-effect-of-neuropsychiatric-comorbidity
#7
Ana Maria Gutierrez-Angel, Iris Enriqueta Martinez-Juarez, Laura Elena Hernandez-Vanegas, Daniel Crail-Melendez
BACKGROUND: Few studies are focused on the quality of life (QOL) of primary caregivers and the effects of the clinical variables of epilepsy and patient psychiatric comorbidity on primary caregivers. PURPOSE: Our main objective was to describe QOL and level of burden (LB) in caregivers of people with epilepsy (PWE) at a tertiary-care hospital in Mexico City. A secondary purpose was to determine if LB and QOL were different between caregivers of patients with neuropsychiatric comorbidity and caregivers of patients without neuropsychiatric comorbidity...
February 15, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29454607/italian-wikipedia-and-epilepsy-an-infodemiological-study-of-online-information-seeking-behavior
#8
Francesco Brigo, Simona Lattanzi, Giorgia Giussani, Laura Tassi, Nicola Pietrafusa, Carlo Andrea Galimberti, Raffaele Nardone, Nicola Luigi Bragazzi, Oriano Mecarelli
Wikipedia is the most commonly accessed source of health information by both healthcare professionals and the lay public worldwide. We aimed to evaluate information-seeking behavior of Internet users searching the Italian Wikipedia for articles related to epilepsy and its treatment. Using Pageviews Analysis, we assessed the total and mean monthly views of articles from the Italian Wikipedia devoted to epilepsy, epileptic syndromes, seizure type, and antiepileptic drugs (AEDs) from January 1, 2015 to October 31, 2017...
February 14, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29454606/psychosocial-outcome-in-epilepsy-after-extratemporal-surgery
#9
Katrin Walther, Müjgan Dogan Onugoren, Michael Buchfelder, Stephanie Gollwitzer, Wolfgang Graf, Burkhard S Kasper, Peter Kriwy, Katrin Kurzbuch, Johannes Lang, Karl Rössler, Stefan Schwab, Michael Schwarz, Hermann Stefan, Hajo M Hamer
OBJECTIVE: Only limited data exist on psychosocial long-term outcome after epilepsy surgery in patients with extratemporal epilepsy. The aim of this study was to investigate psychosocial outcome after extratemporal epilepsy surgery and to assess factors predicting favorable outcome. METHOD: Sixty-five out of 104 eligible patients who had undergone extratemporal epilepsy surgery at our epilepsy center between 1990 and 2015 (mean age: 42.2. years; 75% of the resections in the frontal lobe) completed a questionnaire asking about seizure status, employment status, marital and living situation, driving status, depressive symptoms, and quality of life (QOL)...
February 14, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29454605/knowledge-of-sudden-unexpected-death-in-epilepsy-sudep-among-372-patients-attending-a-german-tertiary-epilepsy-center
#10
Rainer Surges, Randi von Wrede, Thomas Porschen, Christian E Elger
BACKGROUND: There is evidence that the sudden unexpected death in epilepsy (SUDEP) risk can be reduced by good seizure control, nocturnal supervision, and by early cardiopulmonary resuscitation if cardiorespiratory arrest occurs in the aftermaths of generalized tonic-clonic seizures (GTCS). These measures, however, may critically depend on the knowledge of patients and relatives on SUDEP. Here, we assessed the basic knowledge on SUDEP of people with epilepsy at a tertiary epilepsy center in Germany...
February 14, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29454255/effects-of-adjunctive-eslicarbazepine-acetate-on-neurocognitive-functioning-in-children-with-refractory-focal-onset-seizures
#11
Sergiusz Jóźwiak, P Veggiotti, J Moreira, H Gama, F Rocha, P Soares-da-Silva
PURPOSE: This was a phase-II, randomized, double-blind (DB), placebo-controlled study aimed to evaluate neurocognitive effects of eslicarbazepine acetate (ESL) as adjunctive therapy in pediatric patients with refractory focal-onset seizures (FOS). METHODS: Children (6-16years old) with FOS were randomized (2:1) to ESL or placebo. Treatment started at 10mg/kg/day, was up-titrated up to 30mg/kg/day (target dose), and maintained for 8weeks, followed by one-year open-label follow-up...
February 13, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29449140/effectiveness-of-a-multicomponent-self-management-intervention-for-adults-with-epilepsy-zmile-study-a-randomized-controlled-trial
#12
Loes A M Leenen, Ben F M Wijnen, Alfons G H Kessels, HoiYau Chan, Reina J A de Kinderen, Silvia M A A Evers, Caroline M van Heugten, Marian H J M Majoie
BACKGROUND: The objective of the ZMILE study was to compare the effectiveness of a multicomponent self-management intervention (MCI) with care as usual (CAU) in adult patients with epilepsy (PWE) over a six-month period. METHODS: Participants (PWE & relative) were randomized into intervention or CAU groups. Self-report questionnaires were used to measure disease-specific self-efficacy as the primary outcome measure and general self-efficacy, adherence, seizure severity, emotional functioning, quality of life, proactive coping, and side-effects of antiepileptic drugs (AED) as secondary outcome measures...
February 12, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29449139/problems-with-access-to-dental-treatment-for-children-with-epilepsy
#13
Maria Mielnik-Błaszczak, Agnieszka Skawińska-Bednarczyk, Artur Michałowski, Jerzy Błaszczak
INTRODUCTION: Epilepsy is a common medical disorder and due to a variety of barriers, people with epilepsy may not have access to needed healthcare services, particularly based on their place of residence. OBJECTIVES: The aim of the study was to assess access to dental treatment in children and adolescents with epilepsy in Lublin Voivodeship. MATERIAL AND METHODS: Clinical and questionnaire examinations were performed in 107 children and young people, of both sexes, in the ages between 6 and 18years old from the Lublin macroregion...
February 12, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29449138/driving-with-drug-resistant-and-controlled-seizures-from-a-patient-s-perspective-assessment-of-attitudes-and-practices
#14
Lakshman Arcot Jayagopal, Kaeli K Samson, Olga Taraschenko
BACKGROUND: Driving restrictions in epilepsy are intended to safeguard public and personal safety; however, these limitations inhibit socialization, restrict employment, and reduce self-esteem in patients with seizures. A large proportion of patients with seizures continue to drive, and factors leading to noncompliance with driving regulations are poorly understood. Thus, the patients' perspective on driving safety is not incorporated into the existing counseling tools on driving safety in epilepsy...
February 12, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29433949/patient-versus-neurologist-preferences-a-discrete-choice-experiment-for-antiepileptic-drug-therapies
#15
Alan B Ettinger, John A Carter, Krithika Rajagopalan
OBJECTIVE: This assessment was conducted to quantify and compare patient and neurologist preferences regarding antiepileptic drug (AED) attributes for treating epilepsy. METHODS: Patients with epilepsy (≥18years, treated with AEDs) and neurologists were recruited from nationally representative US panels to complete an online survey that included a discrete choice experiment (DCE). Participants chose between two hypothetical AEDs, characterized by six attributes in the DCE, which included 1) level of seizure control/reduction; 2) dosing frequency, 3) diminished coordination and balance, 4) psychiatric issues, 5) diminished energy level, and 6) dietary restrictions...
February 9, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29433948/adherence-barriers-in-pediatric-epilepsy-from-toddlers-to-young-adults
#16
Ana M Gutierrez-Colina, Aimee W Smith, Constance A Mara, Avani C Modi
OBJECTIVE: The objectives of this study were to examine the continuity of adherence barriers across stages of development in pediatric epilepsy and to assess the differential influence of barriers on several important clinical outcomes from early childhood to young adulthood, including adherence, seizures, and health-related quality of life (HRQOL). METHOD: A developmentally representative sample of youth 2-25years with epilepsy was obtained by combining data from five different studies...
February 9, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29433947/antiglutamic-acid-decarboxylase-65-gad65-antibody-associated-epilepsy
#17
REVIEW
Ahmad Daif, Rimas V Lukas, Naoum P Issa, Adil Javed, Stephen VanHaerents, Anthony T Reder, James X Tao, Peter Warnke, Sandra Rose, Vernon L Towle, Shasha Wu
Glutamic acid decarboxylase (GAD) antibody-associated encephalitis causes both acute seizures and chronic epilepsy with predominantly temporal lobe onset. This condition is challenging in diagnosis and management, and the incidence of GAD antibody (Ab)-related epilepsy could be much higher than commonly believed. Imaging and CSF evidence of inflammation along with typical clinical presentations, such as adult onset temporal lobe epilepsy (TLE) with unexplained etiology, should prompt testing for the diagnostic antibodies...
February 9, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29429909/adherence-to-antiepileptic-drugs-in-adolescents-with-epilepsy
#18
Aimee W Smith, Constance A Mara, Avani C Modi
INTRODUCTION: The aims of the current study were to identify patterns and predictors of adherence in adolescents with epilepsy over one year, as well as its impact on seizures and health-related quality of life (HRQOL). METHODS: Forty-eight adolescents with epilepsy (Mage=14.8+1.5, 69% female, 73% White: NonHispanic) and their caregivers completed questionnaires assessing demographics, epilepsy knowledge, side effects, adherence barriers, family functioning, and HRQOL at quarterly clinic visits over one year...
February 8, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29429908/efficacy-of-artisanal-preparations-of-cannabidiol-for-the-treatment-of-epilepsy-practical-experiences-in-a-tertiary-medical-center
#19
Giulia S Porcari, Cary Fu, Emily D Doll, Emma G Carter, Robert P Carson
Medically refractory epilepsy continues to be a challenge worldwide, and despite an increasing number of medical therapies, approximately 1 in 3 patients continues to have seizures. Cannabidiol (CBD), one of many constituents of the Cannabis sativa or marijuana plant, has received renewed interest in the treatment of epilepsy. While highly purified CBD awaits Food and Drug Administration (FDA) approval, artisanal formulations of CBD are readily available and are seeing increased use in our patient population...
February 8, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29429907/relationship-between-office-based-provider-visits-and-emergency-department-encounters-among-publicly-insured-adults-with-epilepsy
#20
Alain Lekoubou, Kinfe G Bishu, Bruce Ovbiagele
INTRODUCTION: The proportion of adults with epilepsy using the emergency department (ED) is high. Among this patient population, increased frequency of office-based provider visits may be associated with lesser frequency of ED encounters, and key patient features may be linked to more ED encounters. METHODS: We analyzed the Medical Expenditure Panel Survey Household Component (MEPS-HC) dataset for years 2003-2014, which represents a weighted sample of 842,249 publicly-insured US adults aged ≥18years...
February 8, 2018: Epilepsy & Behavior: E&B
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