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Epilepsy & Behavior: E&B

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https://www.readbyqxmd.com/read/28285235/knowledge-attitudes-and-practices-among-mothers-of-children-with-epilepsy-a-study-in-a-teaching-hospital
#1
Ali-Asghar Kolahi, Mohsen Abbasi-Kangevari, Pouya Bakhshaei, Farhad Mahvelati-Shamsabadi, Seyed-Hassan Tonekaboni, Ahmad-Reza Farsar
OBJECTIVE: Knowledge about epilepsy and attitudes towards patients with epilepsy can affect measures taken to manage epilepsy and seizures. Support and understanding of mothers is invaluable in enabling children with epilepsy to develop normal life skills in living with epilepsy. In order to identify the educational needs of mothers of children with epilepsy, their knowledge, attitudes, and practices should be assessed. Therefore, we interviewed a group of mothers of children with epilepsy who were referred to a pediatric neurology clinic in a teaching hospital...
March 9, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28285234/caregiver-reported-religious-beliefs-and-complementary-and-alternative-medicine-use-among-children-admitted-to-an-epilepsy-monitoring-unit
#2
Julia Fleming Beattie, Matthew D Thompson, Pamela H Parks, Ruth Q Jacobs, Monisha Goyal
Complementary and alternative medicine (CAM) includes a wide range of practices and products that are generally outside the use of conventional medicine as practiced in Western cultures. Use of CAM in persons with epilepsy is high, even compared to individuals with other chronic health conditions. In this study, we surveyed caregivers of children admitted to a regional epilepsy monitoring unit (EMU) in the southeast United States to assess CAM use among patients (N=225). Thirteen percent of respondents indicated current use of CAM by their child, 16% reported past use, and 43% reported interest in future use, most commonly in marijuana as a potential treatment (23%)...
March 8, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28259063/to-what-extent-does-depression-influence-quality-of-life-of-people-with-pharmacoresistant-epilepsy-in-argentina
#3
Laura Scévola, Mercedes Sarudiansky, Alejandra Lanzillotti, Silvia Oddo, Silvia Kochen, Luciana D'Alessio
INTRODUCTION: Depression is the most frequent psychiatric co-morbidity in patients with epilepsy. Lifetime prevalence of depression is reported more frequently in temporal lobe epilepsy and is estimated at 35%. This co-morbidity appears to be related with various mechanisms. The aim of this study was to determine the quality of life (QoL) of patients with pharmacoresistant epilepsy with and without co-morbid depression in an Argentinean population. METHODS: Patients admitted to the video-EEG monitoring unit during the period 2010-2013 went through a standardized psychiatric assessment using SCID-I (Structured Clinical Interview for Axis I diagnoses of DSM-IV), BDI II (Beck Depression Inventory) GAF (Global assessment of functioning), and Q LES Q-SF (for quality of life)...
February 28, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28256379/outcome-of-childhood-onset-epilepsy-from-adolescence-to-adulthood-transition-issues
#4
REVIEW
R Nabbout, D M Andrade, N Bahi-Buisson, H Cross, I Desquerre, O Dulac, T Granata, E Hirsch, V Navarro, L Ouss, P L Pearl, D Schmidt, E Thiele, P R Camfield, C S Camfield
This is the second of three papers that summarize the second symposium on Transition in Epilepsies held in Paris in June 2016. This paper addresses the outcome for some particularly challenging childhood-onset epileptic disorders with the goal of recommending the best approach to transition. We have grouped these disorders in five categories with a few examples for each. The first group includes disorders presenting in childhood that may have late- or adult-onset epilepsy (metabolic and mitochondrial disorders)...
February 27, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28242476/an-investigation-of-the-characteristics-of-outpatients-with-epilepsy-and-antiepileptic-drug-utilization-in-a-multicenter-cross-sectional-study-in-china
#5
Peimin Yu, Dong Zhou, Weiping Liao, Xin Wang, Yuping Wang, Tiancheng Wang, Yuan Wu, Senyang Lang, Weihong Lin, Yijun Song, Heqing Zhao, Meng Cai, Zhen Hong
OBJECTIVES: This study aimed to describe the distribution of seizure types, clinical characteristics, and antiepileptic drug (AED) utilization in patients with epilepsy visiting tertiary hospitals in China. METHODS: This was an observational, cross-sectional epidemiology study conducted at 11 tertiary hospitals across China from May 2014 to November 2014. A total of 1603 patients, of either sex or any age with confirmed diagnosis of epilepsy, visiting outpatient clinics at tertiary hospitals were screened and enrolled...
February 24, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28242475/importance-of-neuropsychological-and-clinical-features-to-predict-seizure-control-in-medically-treated-patients-with-mesial-temporal-epilepsy-and-hippocampal-sclerosis
#6
Laia Grau-López, Marta Jiménez, Jordi Ciurans, Cynthia Cáceres, Juan Luis Becerra
OBJECTIVE: It is not yet understood why seizures in certain patients with mesial temporal lobe epilepsy and hippocampal sclerosis (MTLE-HS) develop resistance to antiepileptic drugs (AEDs) while others achieve good seizure control with this treatment. We analyzed clinical and neuropsychological features associated with seizure control in patients with MTLE-HS who had not undergone resective surgery. METHODS: We enrolled 40 patients with medically treated MTLE-HS and retrospectively collected the following data from prospective databases: sex, febrile seizures, central nervous system infection, history of head trauma, cognitive impairment, psychiatric disturbances, history of status epilepticus, age at onset of epilepsy, aura, seizure type and frequency, electroencephalography abnormalities, HS side, AEDs, global cognitive status, and neuropsychological functions such as cognitive processing speed, attention and executive functions, verbal and visual memory, language, and visuospatial ability...
February 24, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28242474/antiseizure-antidepressant-and-antipsychotic-medication-prescribing-in-elderly-nursing-home-residents
#7
Sai Praneeth R Bathena, Ilo E Leppik, Andres M Kanner, Angela K Birnbaum
OBJECTIVE: The incidence of epilepsy is highest in the elderly and the prevalence of epilepsy is higher in nursing home residents than in other cohorts. Co-medications that act in the central nervous system (CNS) are frequently prescribed in this population. The objective was to identify the most commonly prescribed antiseizure drugs (ASDs) and determine the frequency of use of antipsychotic and antidepressant medications in elderly nursing home residents receiving ASDs. METHODS: Data were obtained from a pharmacy database serving 18,752 patients in Minnesota and Wisconsin nursing homes...
February 24, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28242310/prevalence-and-impact-of-irritable-bowel-syndrome-in-people-with-epilepsy-methodological-issues
#8
LETTER
Ahad Ashrafi-Asgarabad, Erfan Ayubi, Saeid Safiri
No abstract text is available yet for this article.
February 24, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28238865/an-australian-nationwide-survey-on-medicinal-cannabis-use-for-epilepsy-history-of-antiepileptic-drug-treatment-predicts-medicinal-cannabis-use
#9
Anastasia S Suraev, Lisa Todd, Michael T Bowen, David J Allsop, Iain S McGregor, Carol Ireland, Nicholas Lintzeris
Epilepsy Action Australia conducted an Australian nationwide online survey seeking opinions on and experiences with the use of cannabis-based products for the treatment of epilepsy. The survey was promoted via the Epilepsy Action Australia's main website, on their Facebook page, and by word of mouth. The survey consisted of 39 questions assessing demographics, clinical factors, including diagnosis and seizure types, and experiences with and opinions towards cannabis use in epilepsy. A total of 976 responses met the inclusion criteria...
February 24, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28237833/stable-psychological-functioning-after-surgery-for-epilepsy-an-informant-based-perspective
#10
Marcie L King, Daniel Tranel
OBJECTIVE: Psychological adjustment following surgery for epilepsy has been assessed primarily with self-report measures. In the current work, we investigated pre- to postoperative changes in various dimensions of personality and behavior from the perspective of a well-known family member or friend for 27 patients operated on for medically intractable epilepsy. METHODS: For each patient, a close family member or friend ("informant") provided pre- and postoperative ratings on five dimensions of personality and behavior...
February 23, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28237832/central-nervous-system-anomalies-in-two-females-with-borjeson-forssman-lehmann-syndrome
#11
Burkhard S Kasper, Arnd Dörfler, Nataliya Di Donato, Ekkehard M Kasper, Dagmar Wieczorek, Juliane Hoyer, Christiane Zweier
Borjeson-Forssman-Lehmann syndrome (BFLS) is a rare disorder caused by mutations in the PHF6 gene. It manifests as syndromic X-linked recessive intellectual disability (ID) in males and as sporadic ID due to de novo mutations in females. Clinical features include variable ID and a range of somatic manifestations constituting a distinct phenotype in both males and females, respectively, including seizures in a few. Central nervous system (CNS) imaging data are largely unavailable for BFLS. Here we report on CNS MRI findings from two female individuals with BFLS due to a de novo duplication in PHF6 who presented with typical BFLS and epilepsy...
February 23, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28237318/strokes-are-possible-complications-of-cannabinoids-use
#12
REVIEW
Valérie Wolff, Emilie Jouanjus
It is critically important to identify all factors that may play a role in the recent increase of the incidence of stroke among the young population. Considering the worldwide use of cannabinoids (cannabis and synthetic cannabinoids), the recent legalization of their consumption in some countries, and their supposed involvement in cardiovascular events, we evaluated their role in the occurrence of neurovascular complications among the young. Ninety-eight patients were described in the literature as having a cannabinoids-related stroke (85 after cannabis use and 13 after synthetic cannabinoids)...
February 23, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28237319/epilepsy-treatment-in-adults-and-adolescents-expert-opinion-2016
#13
REVIEW
Jerry J Shih, Julia B Whitlock, Nicole Chimato, Emily Vargas, Steven C Karceski, Ryan D Frank
INTRODUCTION: There are over twenty anti-seizure medications and anti-seizure devices available commercially in the United States. The multitude of treatment options for seizures can present a challenge to clinicians, especially those who are not subspecialists in the epilepsy field. Many clinical questions are not adequately answered in double-blind randomized controlled studies. In the presence of a knowledge gap, many clinicians consult a respected colleague with acknowledged expertise in the field...
February 22, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28236729/parental-stress-pediatric-quality-of-life-and-behavior-at-baseline-and-one-year-follow-up-results-from-the-febstat-study
#14
Ruth C Shinnar, Shlomo Shinnar, Dale C Hesdorffer, Kathryn O'Hara, Terrie Conklin, Karen Mohler Cornett, Diana Miazga, Shumei Sun
Febrile status epilepticus is a serious and frightening event in the life of the child and parent. It is regarded as a medical emergency with potential long lasting consequences. The purpose of this study was to look at the immediate and long term effects of such an event on parental stress and parents' perception of their child's physical and psychosocial wellbeing. METHODS: From 2003 to 2010, 199 subjects, age 1 month to 5 years, were recruited as part of a prospective, multicenter study (FEBSTAT) of consequences of febrile status epilepticus (FSE)...
February 22, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28236728/language-plasticity-after-hemispherotomy-of-the-dominant-hemisphere-in-3-patients-implication-of-non-linguistic-networks
#15
Christine Bulteau, Isabelle Jambaqué, Catherine Chiron, Sebastian Rodrigo, Georg Dorfmüller, Olivier Dulac, Lucie Hertz-Pannier, Marion Noulhiane
The neural networks involved in language recovery following hemispherotomy of the dominant hemisphere after language acquisition in children remain poorly known. Twelve hemispherotomized children (mean age at surgery: 11.3years) with comparable post-operative neuropsychological patterns underwent multi-task language functional MRI. Three of them had recovered from an initial postoperative aphasia i.e., hemispherotomy was performed on the language-dominant hemisphere. Our main results revealed (1) perisylvian activations in all patients after either left or right hemispherotomy; (2) no differences in activations between groups regarding the side of hemispherotomy; (3) additional activations in pre-frontal (3/3) and hippocampal/parahippocampal and occipito-parietal (2/3) areas, when comparing language activation in each of the three subjects with hemispherotomy of the language-dominant hemisphere to the group of 9 non-dominant hemispherotomized patients...
February 22, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28236727/health-related-quality-of-life-in-double-blind-phase-iii-studies-of-brivaracetam-as-adjunctive-therapy-of-focal-seizures-a-pooled-post-hoc-analysis
#16
Christian Brandt, Simon Borghs, Sami Elmoufti, Knut Mueller, Rebecca Townsend, Christine de la Loge
PURPOSE: The effect of adjunctive brivaracetam on health-related quality of life (HRQoL) was assessed in a post-hoc analysis using pooled data from three randomized, double-blind, placebo-controlled Phase III studies in patients with refractory focal seizures (NCT00490035, NCT00464269, and NCT01261325). METHODS: The Patient-Weighted Quality of Life in Epilepsy Questionnaire (QOLIE-31-P) was completed at randomization, and weeks 4, 8 (in two of three studies), and 12 (end of the treatment period)...
February 22, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28236726/the-influence-of-epilepsy-on-children-s-perception-of-self-concept
#17
Flora Lopes Scatolini, Karina Piccin Zanni, Luzia Iara Pfeifer
The diagnosis of epilepsy can lead to changes in the patient's perception due to factors such as learning and behavioral problems, lack of academic motivation, and low self-esteem. This study aimed to evaluate and compare the knowledge of self-concept in children with epilepsy and those with typical development and verify whether gender and age influence this perception. Eighty children of both sexes, aged between 8 and 14years, participated in this study. The children were divided into two groups: the epilepsy group, which consisted of 40 children diagnosed with epilepsy, and the control group, which consisted of 40 children with typical development and comparable to group 1 according to sex and age...
February 22, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28236725/diagnostic-implications-of-review-of-systems-questionnaires-to-differentiate-epileptic-seizures-from-psychogenic-seizures
#18
Wesley T Kerr, Emily A Janio, Chelsea T Braesch, Justine M Le, Jessica M Hori, Akash B Patel, Sarah E Barritt, Norma L Gallardo, Janar Bauirjan, Andrea M Chau, Eric S Hwang, Emily C Davis, David Torres-Barba, Andrew Y Cho, Jerome Engel, Mark S Cohen, John M Stern
OBJECTIVE: Early and accurate diagnosis of patients with psychogenic nonepileptic seizures (PNES) leads to appropriate treatment and improves long-term seizure prognosis. However, this is complicated by the need to record seizures to make a definitive diagnosis. Suspicion for PNES can be raised through knowledge that patients with PNES have increased somatic sensitivity and report more positive complaints on review-of-systems questionnaires (RoSQs) than patients with epileptic seizures...
February 22, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28236724/clinical-and-sociodemographic-variables-associated-with-interictal-dysphoric-disorder-and-interictal-personality-in-patients-with-drug-resistant-temporal-lobe-epilepsy-a-controlled-study
#19
Gerardo Maria de Araújo Filho, Bruna Tarifa, Raquel Espagnolla Santos, Ana Laura de Oliveira Dias, Júlia Rodrigues Leandro Ulliano, Lucia Helena Neves Marques
Psychiatric disorders (PD) have an elevated prevalence and an important negative impact on patients with epilepsy (PWE) since they are associated with lower quality of life and clinical refractoriness. However, it is also necessary to identify behavioral conditions possibly associated with epilepsy that are not part of the standard psychiatric classifications, such as Interictal Dysphoric Disorder (IDD) and Interictal Personality (IP). The frequency of IDD and IP in patients with drug-resistant temporal lobe epilepsy and mesial temporal sclerosis (TLE-MTS) was assessed...
February 22, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28236698/impact-of-seizure-frequency-reduction-on-health-related-quality-of-life-among-clinical-trial-subjects-with-refractory-partial-onset-seizures-a-pooled-analysis-of-phase-iii-clinical-trials-of-eslicarbazepine-acetate
#20
Fulton F Velez, T Christopher Bond, Kathryn P Anastassopoulos, Xuezhe Wang, Rui Sousa, David Blum, Joyce A Cramer
BACKGROUND: Subjects who received eslicarbazepine acetate (ESL) as adjunctive therapy experienced significantly greater seizure frequency reduction (SFR) than placebo in three phase III, randomized, double-blind trials. This analysis compared changes in health-related quality of life (HRQOL) between treatment responders and non-responders across the pooled, per-protocol population (N=842) using the validated Quality of Life in Epilepsy Inventory-31 (QOLIE-31). METHODS: QOLIE-31 scores were calculated for Total Score (TS) and seven subscales; higher scores indicate better HRQOL...
February 22, 2017: Epilepsy & Behavior: E&B
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