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Epilepsy & Behavior: E&B

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https://www.readbyqxmd.com/read/28821006/adherence-to-antiepileptic-drugs-in-children-and-adolescents-a-retrospective-study-in-primary-care-settings-in-germany
#1
Louis Jacob, Hajo M Hamer, Karel Kostev
OBJECTIVE: The goal of this study was to analyze adherence to antiepileptic drugs (AED) in children and adolescents treated in pediatric practices in Germany. METHODS: The present study included patients aged between 2 and 17years who were diagnosed with epilepsy (ICD-10: G40) and had received at least two prescriptions of AED between January 2006 and December 2015 in 243 pediatric practices in Germany. The medication possession ratio (MPR) was used to estimate adherence, and patients with a MPR greater than 80% were considered adherent...
August 15, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28821005/anticonvulsant-effect-of-cannabidiol-in-the-pentylenetetrazole-model-pharmacological-mechanisms-electroencephalographic-profile-and-brain-cytokine-levels
#2
Luciano R Vilela, Isabel V Lima, Érica B Kunsch, Hyorrana Priscila P Pinto, Aline S de Miranda, Érica Leandro M Vieira, Antônio Carlos P de Oliveira, Marcio Flávio D Moraes, Antônio L Teixeira, Fabricio A Moreira
Cannabidiol (CBD), the main nonpsychotomimetic compound from Cannabis sativa, inhibits experimental seizures in animal models and alleviates certain types of intractable epilepsies in patients. Its pharmacological profile, however, is still uncertain. Here we tested the hypothesis that CBD anticonvulsant mechanisms are prevented by cannabinoid (CB1 and CB2) and vanilloid (TRPV1) receptor blockers. We also investigated its effects on electroencephalographic (EEG) activity and hippocampal cytokines in the pentylenetetrazole (PTZ) model...
August 15, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28818811/brain-tumors-and-epileptic-spasms-natural-history-and-outcomes
#3
Viviana Benitez, Peter E Manley, Liliana C Goumnerova, Chellamani Harini, Nicole J Ullrich
While brain tumors are a frequent cause of seizures, they rarely cause epileptic spasms (ES). The objective of this study was to investigate features of tumor-associated ES. We conducted a retrospective review of patients with ES and a brain tumor. Demographics; pathologic, radiologic, and EEG data; treatment response; and long-term outcome were collected. Twenty four patients were identified; 11 met inclusion criteria. Epileptic spasm (ES) onset occurred prior to tumor diagnosis in seven patients (63%), and after tumor resection in 4 patients (36%)...
August 14, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28818810/evaluating-quality-of-life-in-epilepsy-the-role-of-screening-for-adverse-drug-effects-depression-and-anxiety
#4
Jean-Arthur Micoulaud-Franchi, Fabrice Bartolomei, Roderick Duncan, Aileen McGonigal
OBJECTIVE: The objective of this study was to evaluate the contribution of validated screening tools for antiepileptic drug (AED) adverse effects, depression, and anxiety to measure the quality of life (QoL) in people with epilepsy (PWE). METHODS: Patients in a tertiary epilepsy service were screened for quality of life (using QOLIE-31), major depressive disorder (MDD) (NDDI-E), generalized anxiety disorder (GAD) (GAD-7), and AED effects (AEP). Mini International Neuropsychiatric Interview (MINI) generalized anxiety disorder module was also performed...
August 14, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28806633/provision-of-sudden-unexpected-death-in-epilepsy-sudep-information-among-malaysian-parents-of-children-with-epilepsy
#5
Choong Yi Fong, Wei Kang Lim, Ann Nie Kong, Pei Lin Lua, Lai Choo Ong
Sudden unexpected death in epilepsy (SUDEP) is an important cause of mortality in epilepsy. To date, there is only one published UK study evaluating information provision of SUDEP among parents of children with epilepsy (CWE), and there are no studies published from Asia. Although SUDEP information provision is recommended among parents of CWE, it is uncertain if these recommendations are applicable to Asian countries due to the different cultural attitude towards epilepsy. Our prospective cohort study consisted of multiethnic parents of children with epilepsy (CWE) seen in a tertiary hospital in Malaysia...
August 11, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28806632/clinical-utility-of-serum-lactate-levels-for-differential-diagnosis-of-generalized-tonic-clonic-seizures-from-psychogenic-nonepileptic-seizures-and-syncope
#6
Ebru Apaydın Doğan, Ali Ünal, Aslıhan Ünal, Çağla Erdoğan
BACKGROUND: The differential diagnosis of generalized tonic-clonic seizures (GTCS), psychogenic nonepileptic seizures (PNES), and syncope constitutes a major challenge. Misdiagnosis rates up to 20 to 30% are reported in the literature. PURPOSE: To assess the clinical utility of serum lactate levels for differentiation of GTCS, PNES, and syncope based on gender differences. METHODS: Data from 270 patients were evaluated retrospectively. Only patients ≥18 years old with the final diagnosis of GTCS, PNES, or syncope in their chart were recruited...
August 11, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28806631/unraveling-complex-relationships-among-dysphoric-disorder-localization-related-epilepsy-and-mood-disorders
#7
Tetsufumi Suda, Yasutaka Tatsuzawa, Taichi Mogi, Aihide Yoshino
BACKGROUND: Dysphoric disorder (DD), characterized by intermittent pleomorphic symptoms, has been believed to be specific to epilepsy. However, our previous study revealed that DD in patients with localization-related epilepsy was associated with a lifetime diagnosis of mood disorders. The present study was conducted to estimate the prevalence of DD in patients with mood disorders, but not epilepsy, and to identify the clinical similarities and differences of DD in patients with either epilepsy or mood disorders...
August 11, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28802554/response-to-physical-exercise-to-manage-sleep-problems-in-pediatric-patients-with-epilepsy-and-adhd
#8
LETTER
Ozalp Ekinci, Çetin Okuyaz
No abstract text is available yet for this article.
August 9, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28778667/physical-exercise-to-manage-sleep-problems-in-pediatric-patients-with-epilepsy-and-adhd
#9
LETTER
Claudio Andre Barbosa de Lira, Marília Santos Andrade, Marco Túlio de Mello, Rodrigo Luiz Vancini
No abstract text is available yet for this article.
August 1, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28778058/response-to-adrenocorticotropic-in-attention-deficit-hyperactivity-disorder-like-symptoms-in-electrical-status-epilepticus-in-sleep-syndrome-is-related-to-electroencephalographic-improvement-a-retrospective-study
#10
Attila Altunel, Emine Özlem Altunel, Ali Sever
INTRODUCTION: Encephalopathy with electrical status epilepticus in sleep (ESES) syndrome is a rare epilepsy syndrome of childhood that is characterized by sleep-induced epileptiform discharges and problems with cognition or behavior. The neuropsychiatric symptoms in ESES syndrome, among which the ADHD-like symptoms are prominent, bear a close resemblance to symptoms in various developmental disorders. Positive response to adrenocorticotropic hormone (ACTH) is associated with the normalization of the EEG and improvement of neuropsychiatric function...
August 1, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28768229/individual-resilience-as-a-strategy-to-counter-employment-barriers-for-people-with-epilepsy-in-zimbabwe
#11
Jacob Mugumbate, Mel Gray
Understanding individual resilience helps to improve employment opportunities of people with epilepsy. This is significant because, in Zimbabwe, as in many other countries in the Global South, people with epilepsy encounter several barriers in a context of less-than-ideal public services. Despite this disadvantage, some people with epilepsy have better employment outcomes for reasons including level of seizure control, social background, employment support services, and individual resilience. This article reports on data from participants (n=8), who were part of a larger study (n=30) on employment experiences of people with epilepsy in Harare...
July 30, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28756337/epilepsy-related-romantic-and-sexual-relationship-problems-and-concerns-indications-from-internet-message-boards
#12
Wendy R Miller, Amanda N Gesselman, Justin R Garcia, Doyle Groves, Janice M Buelow
The objective of this study was to, utilizing a Big Data set and innovative methods, explore romantic and sexual relationship-related concerns among people with epilepsy and their partners. We applied Word Adjacency Graph modeling to more than 2000 message board posts, and five distinct categories of romantic and sexual relationship-related concerns emerged. We conclude that persons with epilepsy are at particular risk for the experience of decrements in their romantic and sexual relationships, which can negatively impact their self-management and overall health...
July 27, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28738284/awareness-attitudes-toward-epilepsy-and-first-aid-knowledge-of-seizures-of-hospital-staff-in-henan-china
#13
Ting Zhao, Yajuan Gao, Xuerui Zhu, Na Wang, Yanan Chen, Jiahui Zhang, Guinv He, Yan Feng, Jun Xu, Xiong Han, Jiewen Zhang
AIM: The aim of this study was to evaluate awareness of, attitudes toward, and first aid knowledge of seizures of hospital staff in Henan, China. METHOD: Two hundred nineteen hospital staff, including doctors, nurses, medical technicians, logisticians, and executives working at tertiary hospitals in Henan, China, completed the survey from March to September in 2016. The data comprised the demographic data section, awareness of epilepsy section, attitude toward epilepsy section, and first aid knowledge of seizure attack section...
July 21, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28734750/deconstructing-stigma-in-psychogenic-nonepileptic-seizures-an-exploratory-study
#14
Gregg H Rawlings, Ian Brown, Markus Reuber
Psychogenic nonepileptic seizures (PNES) are classified as a mental disorder, the manifestations of which superficially resemble epileptic seizures. There is a notable lack of in-depth qualitative or quantitative studies investigating the stigma attached to PNES. The current study is an exploratory analysis into the nature of perceived stigma in those with PNES when compared with individuals with epilepsy. Individuals with epilepsy (n=78) and PNES (n=47) were recruited from a United Kingdom hospital or membership-led organizations for individuals living with seizures...
July 19, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28734197/life-impact-of-caregiving-for-severe-childhood-epilepsy-results-of-expert-panels-and-caregiver-focus-groups
#15
Mark P Jensen, Kendra S Liljenquist, Fraser Bocell, Arnold R Gammaitoni, Carey R Aron, Bradley S Galer, Dagmar Amtmann
Severe epilepsy in children and young adults can significantly affect the lives of their caregivers. However, the lack of a reliable and valid measure of caregiver impact has limited our understanding of the scope and correlates of this impact, as well as our ability to measure the effects of treatments that could lessen it. The purpose of this study was to facilitate focus groups and interviews with an international group of clinician experts and caregivers to identify the most important domains that should be assessed in a measure of caregiver impact...
July 19, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28734196/on-status-epilepticus-and-pins-a-systematic-content-analysis
#16
Naim Mahroum, Abdulla Watad, Nicola Luigi Bragazzi, Howard Amital, Kassem Sharif, Samaa Watad, Giulia Adavastro, Giovanna Canepa, Francesco Brigo, Mohammad Adawi
Status epilepticus (SE) can be defined as abnormally prolonged, persistent, or recurrent clinical and/or electrographic epileptic activity and, as such, is a challenging medical emergency requiring an aggressive treatment aimed at promptly terminating the seizures. It imposes a relevant clinical burden, both in terms of comorbidity and mortality. In the era of the Web 2.0, most people search the Web to obtain SE-related information. The current investigation aimed at qualitatively characterizing the pins related to SE: Pinterest, "the world's catalog of ideas", is a visual social networking site that enables users to freely upload visual material, to bookmark, and to share it (repin)...
July 19, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28734195/implementation-of-psychological-clinical-trials-in-epilepsy-review-and-guide
#17
REVIEW
Avani C Modi, Janelle Wagner, Aimee W Smith, Tanja S Kellermann, Rosa Michaelis
The International League Against Epilepsy (ILAE) Neuropsychiatry commission and United States Institute of Medicine report both identified cognitive and psychological comorbidities as a significant issue for individuals with epilepsy, with rates as high as 60%. However, there is a paucity of evidence-based treatments for many psychological conditions (e.g., learning disorders, cognitive disorders, behavioral disorders). Because of inherent challenges in the implementation of psychological therapy trials and specific considerations for the population with epilepsy, the focus of the current review was to provide guidance and recommendations to conduct psychological trials for individuals with epilepsy...
July 19, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28732683/a-country-fool-s-progress
#18
EDITORIAL
Peter Wolf
No abstract text is available yet for this article.
July 18, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28732262/attitudes-toward-epilepsy-and-perceptions-of-epilepsy-related-stigma-in-korean-evangelical-christians
#19
Sang-Ahm Lee, Eun-Ju Choi, Ji-Ye Jeon, Joon-Hyun Paek
PURPOSE: The scriptural description of Jesus driving out an evil spirit from a boy with epilepsy supported the idea of the spiritual nature of epilepsy for centuries. Korea has a shorter history of Christianity than the Western world. We determined whether there are differences in attitudes toward epilepsy and perception of epilepsy-related stigma between people with and without belief in evangelical Christianity in Korea. METHODS: Data were collected from evangelical churches and theological colleges...
July 18, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28732261/predictors-of-disclosure-management-behavior-at-the-end-of-1-year-follow-up-in-korean-adults-with-newly-diagnosed-epilepsy
#20
Sang-Ahm Lee, Soon-Kee No, Hyungkook Park, Ok-Joon Kim, Jee-Hyun Kwon, Ji-Yeon Ryu, Sang-Moo Lee, Kwang-Deog Jo
PURPOSE: Epilepsy is a concealable stigmatizing condition. We investigated the factors predicting disclosure management behavior in Korean adults with newly diagnosed epilepsy. METHODS: This longitudinal multicenter study included Korean adults with newly diagnosed epilepsy. Using statistical analyses, we determined at the end of a 1-year follow-up whether Disclosure Management Scale (DMS) scores were predicted by demographic, clinical, and psychosocial variables, including felt stigma, stress coping style, personality traits, social support, and experienced discrimination from society...
July 18, 2017: Epilepsy & Behavior: E&B
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