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Epilepsy & Behavior: E&B

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https://www.readbyqxmd.com/read/29223932/pregnancy-related-knowledge-of-women-with-epilepsy-an-internet-based-survey-in-german-speaking-countries
#1
Carolin Dierking, Thomas Porschen, Uwe Walter, Johannes Rösche
There are several issues, which have to be acknowledged, when treating women with epilepsy (WWE). The need for counseling WWE in Germany with epilepsy on pregnancy-related matters was stressed in several papers and medical guidelines. Physicians treating WWE in Germany therefore should be aware of the information needs of their patients. We aimed to determine the level of pregnancy-related knowledge of WWE and their informational needs concerning pregnancy and childbirth issues in German-speaking countries by an internet-based survey...
December 7, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29223931/prevalence-of-anxiety-disorders-in-epilepsy
#2
Mariusz S Wiglusz, Jerzy Landowski, Wiesław J Cubała
OBJECTIVE: Anxiety disorders (ADs) are common in patients with epilepsy (PWE). The aim of this study was to estimate the prevalence of specific ADs in outpatients with epilepsy. METHODS: A group of 118 consecutive outpatients with epilepsy were screened, and 96 patients meeting inclusion criteria were examined by a trained psychiatrist using Structured Clinical Interview (SICD-I) for Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition (Text Revision) (DSM-IV-TR)...
December 7, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29223414/juvenile-myoclonic-epilepsy-an-insider-s-guide
#3
EDITORIAL
Timothy J Counihan
No abstract text is available yet for this article.
December 6, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29223007/examining-health-service-utilization-hospital-treatment-cost-and-mortality-of-individuals-with-epilepsy-and-status-epilepticus-in-new-south-wales-australia-2012-2016
#4
Rebecca J Mitchell, Geoffrey Herkes, Armin Nikpour, Andrew Bleasel, Patti Shih, Sanjyot Vagholkar, Frances Rapport
This study examined the health service utilization and hospital treatment cost of individuals with epilepsy by age group, mortality within 30days, and surgical outcomes for individuals with refractory epilepsy in New South Wales (NSW), Australia. A retrospective examination of linked hospitalization and mortality data for individuals hospitalized with a diagnosis of epilepsy during 2012-2016. Hospitalized incidence rates per 1000 population were calculated, and negative binomial regression was used to examine temporal trends...
December 6, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29223006/the-temple-star-transitional-model-of-care-for-epilepsy-the-outcome-of-a-quality-improvement-project
#5
Suzanne L Crowley, Susan Byrne, Sandra McNulty, Kim Keating, Therese Nestor, Yvonne Owen, Declan O'Rourke, Bryan Lynch, Amre Shahwan, Mary D King
OBJECTIVE: The aim and objective of this study was to assess the knowledge and views of parents on transitional and adolescent care in young adults with epilepsy, and to develop a transitional and adolescent program for epilepsy. METHODS: Data were collected from questionnaires completed by parents during focus groups exploring transitional care and inherent issues for young adults, aged 12-18years, with epilepsy. The questionnaire assessed the current knowledge and views of parents of children with epilepsy on transitional care, and following a presentation on "Transition in Epilepsy" (including themes such as self-advocacy, independent healthcare behavior, sexual health, psychosocial support, educational and vocational planning, health and lifestyle issues) assessed feedback on the proposed model of care in transitional and adolescent care...
December 6, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29221763/cognitive-impairment-and-quality-of-life-of-people-with-epilepsy-and-neurocysticercosis-in-zambia
#6
Anne L Nau, Kabemba E Mwape, Jasmin Wiefek, Kathie Schmidt, Emmanuel Abatih, Pierre Dorny, Nicolas Praet, Clarance Chiluba, Holger Schmidt, Isaac K Phiri, Andrea S Winkler, Sarah Gabriël, Joachim Blocher
Cognitive impairment and quality of life (Qol) are important to assess the burden of epilepsy and neurocysticercosis (NCC), which are common but neglected in Sub-Saharan Africa (SSA). The aims of this study were to assess cognitive performance and Qol of people with epilepsy (PWE) in Zambia and to explore differences in PWE with and without NCC. In this community based, cross-sectional case-control-study, 47 PWE and 50 healthy controls completed five neuropsychological tests (Mini Mental State Examination (MMSE), Digit Span, Selective Reminding Test (SRT), Spatial Recall Test (SPART), Test Battery of Attentional Performance (TAP)) and a World Health Organization (WHO) questionnaire of Qol...
December 5, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29203274/the-effect-of-a-modular-education-program-for-children-with-epilepsy-and-their-parents-on-disease-management
#7
Fatma Dilek Turan Gürhopur, Ayşegül Işler Dalgiç
OBJECTIVE: The objective of this study was to evaluate the efficacy of Modular Education Program for Children with Epilepsy and Their Parents on disease management. The program was prepared by researchers in an interdisciplinary team. METHOD: Children with epilepsy and their parents were included in a randomized controlled study using a pre-posttest design. All participants of the modular education program (n=184 (92 children and their 92 parents')) answered a lot of scales immediately before the program...
December 1, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29202277/optimizing-clobazam-treatment-in-patients-with-lennox-gastaut-syndrome
#8
Jouko Isojarvi, Barry E Gidal, Steve Chung, Robert T Wechsler
Given the complexities managing Lennox-Gastaut syndrome (LGS)-comorbid conditions, multiple associated seizure types that tend to be refractory to treatment-dosage optimization of antiepileptic drug (AED) treatment is a challenge. In the absence of clinical trial data on optimization of AED dosage in patients with LGS, dose titration is guided by personal experience, anecdotal evidence, and specific patient factors (age, comorbid conditions and medications, seizure types, etc.). The goal of this study was to determine whether a 20% increase in adjunctive clobazam was a reasonable benchmark for improved seizure response in patients with LGS who had responded to adjunctive clobazam treatment during a 12-week lead-in trial...
December 1, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29195160/modulation-of-the-anticonvulsant-effect-of-swim-stress-by-agmatine
#9
Taraneh Bahremand, Pooya Payandemehr, Kiarash Riazi, Ali Reza Noorian, Borna Payandemehr, Mohammad Sharifzadeh, Ahmad Reza Dehpour
Agmatine is an endogenous l-arginine metabolite with neuroprotective effects in the stress-response system. It exerts anticonvulsant effects against several seizure paradigms. Swim stress induces an anticonvulsant effect by activation of endogenous antiseizure mechanisms. In this study, we investigated the interaction of agmatine with the anticonvulsant effect of swim stress in mice on pentylenetetrazole (PTZ)-induced seizure threshold. Then we studied the involvement of nitric oxide (NO) pathway and endogenous opioid system in that interaction...
November 28, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29190579/efficacy-and-safety-of-vigabatrin-in-japanese-patients-with-infantile-spasms-primary-short-term-study-and-extension-study
#10
Yoko Ohtsuka
Vigabatrin was approved for the treatment of infantile spasms by the US Food and Drug Administration, but not in Japan at the time of initiating this clinical study because of concerns about irreversible peripheral visual field defects (VFDs). This study evaluated the efficacy and safety of vigabatrin for Japanese patients with infantile spasms. Of 15 patients (aged ≥4weeks and <2years) enrolled, with the exception of two patients who did not receive vigabatrin, 13 were treated with a titrated dosage of vigabatrin (50-150mg/kg/day; limited to 3000mg/day)...
November 27, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29186699/seizure-induced-activation-of-the-hpa-axis-increases-seizure-frequency-and-comorbid-depression-like-behaviors
#11
Andrew Hooper, Rumzah Paracha, Jamie Maguire
Our laboratory recently demonstrated that seizures activate the hypothalamic-pituitary-adrenal (HPA) axis, increasing circulating levels of corticosterone (O'Toole et al., 2013). Given the well-established proconvulsant actions of corticosterone, we hypothesized that seizure-induced activation of the HPA axis may contribute to future seizure susceptibility. Further, since hypercortisolism is associated with depression, we propose that seizure-induced activation of the HPA axis may contribute to comorbid depression and epilepsy...
November 26, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29186698/effect-of-atorvastatin-on-behavioral-alterations-and-neuroinflammation-during-epileptogenesis
#12
Clarissa Vasconcelos de Oliveira, Jéssica Grigoletto, Julia Marion Canzian, Marta Maria Medeiros Frescura Duarte, Thiago Duarte, Ana Flávia Furian, Mauro Schneider Oliveira
Temporal lobe epilepsy (TLE) is the most frequent and medically refractory type of epilepsy in humans. In addition to seizures, patients with TLE suffer from behavioral alterations and cognitive deficits. Poststatus epilepticus model of TLE induced by pilocarpine in rodents has enhanced the understanding of the processes leading to epilepsy and thus, of potential targets for antiepileptogenic therapies. Clinical and experimental evidence suggests that inflammatory processes in the brain may critically contribute to epileptogenesis...
November 26, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29183659/are-there-gender-differences-in-those-diagnosed-with-psychogenic-nonepileptic-seizures
#13
Lorna Myers, Robert Trobliger, Kirsty Bortnik, Marcelo Lancman
OBJECTIVE: The objective of the study was to determine whether male and female populations of patients with psychogenic nonepileptic seizures (PNES) differ, in terms of demographic, social/clinical, and etiological factors as well as psychological measures. BACKGROUND: Psychogenic nonepileptic seizures are overrepresented by females; therefore, information about PNES in males is limited. Only a handful of studies have examined PNES and gender, and of those, one was a literature review and with the exception of two, most have had small sample sizes...
November 25, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29182948/mozart-s-music-in-children-with-drug-refractory-epileptic-encephalopathies-comparison-of-two-protocols
#14
Giangennaro Coppola, Francesca Felicia Operto, Francesca Caprio, Giuseppe Ferraioli, Simone Pisano, Andrea Viggiano, Alberto Verrotti
In this prospective, randomized, open label study, we compared the effect on seizure recurrence and quality-of-life parameters, of two different protocols of music therapy in children and adolescents with refractory epileptic encephalopathies. Nine out of 19 patients (13 males and 6 females, aged between 1 and 24years) were randomized to listen to Mozart's sonata in D major for two pianos K448 for 2h/day for 2weeks; other 10 children were randomized on a set of Mozart's compositions. In group 1 (K448), 2/9 children (22...
November 25, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29179106/quality-of-life-in-adults-with-epilepsy-is-associated-with-anticonvulsant-polypharmacy-independent-of-seizure-status
#15
Halley B Alexander, Donna K Broshek, Mark Quigg
RATIONALE: Polypharmacy, sometimes necessary to control epilepsy, can result in adverse effects that may affect quality of life (QOL). Our purpose was to determine the association of polypharmacy with QOL. METHODS: Two hundred seven patients with epilepsy were surveyed on characteristics within the last 4weeks: QOL Quality of Life in Epilepsy-Patient-Weighted (QOLIE-10-P) and seizure status (seizure-free or not), demographics, epilepsy characteristics, insomnia, sleepiness, mood, sleep-wake timing, healthcare use, and employment...
November 24, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29179105/predicting-epileptic-seizure-control-during-pregnancy
#16
Frank J E Vajda, T J O'Brien, J E Graham, A A Hitchcock, C M Lander, M J Eadie
OBJECTIVE: The objective of the study was to assess whether the type of seizure disorder present in the prospective mother with epilepsy, her use of antiepileptic drugs (AEDs) in early pregnancy, and her seizure control before pregnancy help predict her prospects for seizure freedom throughout pregnancy. METHODS: This paper is based on data accumulated in the Australian Pregnancy Register (APR) between 1998 and late 2016. Information was analyzed concerning epileptic seizure occurrence and AED therapy taken before and during pregnancy, using simple statistical and confidence interval (C...
November 24, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29179104/who-are-the-individuals-diagnosed-with-epilepsy-using-the-public-health-system-in-the-city-of-pelotas-southern-brazil
#17
César Augusto Häfele, Matheus Pintanel Freitas, Bianca Lamas Gervini, Raquel Machado de Carvalho, Airton José Rombaldi
The aim of this study was to describe sociodemographic, clinical, behavioral, nutritional, and health-related variables from people with epilepsy. A descriptive observational study was carried out in the city of Pelotas, southern Brazil. Sociodemographic, clinical, behavioral, nutritional, and health-related variables were collected. A univariate analysis was performed, calculating the measures of central tendency for continuous variables and proportions for categorical ones. The sample consisted of 101 people, age ranging from 12 to 75years, mostly male (50...
November 24, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29179103/factors-associated-with-behavioral-problems-and-cognitive-impairment-in-children-with-epilepsy-of-kinshasa-democratic-republic-of-the-congo
#18
Thierry Matonda-Ma-Nzuzi, Samuel Mampunza Ma Miezi, Magloire Nkosi Mpembi, Diane Muanza Mvumbi, Michel Ntentani Aloni, Fanny Malendakana, Davin Mpaka Mbeya, Gilbert Mananga Lelo, Dominique Charlier-Mikolajczak
BACKGROUND: Behavioral problems and cognitive impairment are common in children with epilepsy (CWE). In sub-Saharan Africa, little is known about these comorbidities particularly their relationships with socioeconomic features. The goal of this study was to identify clinical and socioeconomic factors associated with behavioral problems and cognitive impairment in CWE of Kinshasa (Democratic Republic of the Congo). METHODS: This cross-sectional hospital-based study had included 104 CWE aged 6 to 17years...
November 24, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29179102/electroencephalographic-findings-in-anti-n-methyl-d-aspartate-receptor-encephalitis-in-children-a-series-of-12-patients
#19
Mirac Yildirim, Bahadir Konuskan, Dilek Yalnizoglu, Haluk Topaloglu, Ilknur Erol, Banu Anlar
OBJECTIVE: Anti-N-methyl-d-aspartate receptor encephalitis (a-NMDARe) is an acute or subacute encephalopathy where electroencephalogram (EEG) is frequently obtained as part of the workup. Although no diagnostic EEG finding has been described so far, the definition of specific or typical patterns might help to distinguish this group among various encephalopathies of childhood. We examined EEG recordings of our patients with a-NMDARe in order to describe the most frequent findings. METHODS: Clinical and laboratory data and digital EEG recordings of 12 pediatric patients diagnosed with a-NMDARe in two major child neurology centers are evaluated...
November 24, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29179101/the-cinderella-syndrome-a-narrative-study-of-social-curfews-and-lifestyle-restrictions-in-juvenile-myoclonic-epilepsy
#20
Teresa Leahy, Michael J Hennessy, Timothy J Counihan
Several factors are thought to contribute to inadequate seizure control in patients with juvenile myoclonic epilepsy (JME), including drug resistance, neuropsychiatric comorbidity, and poor lifestyle choices. Recent evidence supports the existence of frontal lobe microstructural deficits and behavioral changes that may contribute to poor seizure control in a minority of patients. Counseling patients on the importance of adequate sleep hygiene and alcohol restriction is an important part of the management strategy for patients with JME...
November 24, 2017: Epilepsy & Behavior: E&B
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