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Epilepsy & Behavior: E&B

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https://www.readbyqxmd.com/read/28222341/patient-emotions-and-perceptions-of-antiepileptic-drug-changes-and-titration-during-treatment-for-epilepsy
#1
Jesse Fishman, Greg Cohen, Colin Josephson, Ann Marie Collier, Srikanth Bharatham, Ying Zhang, Imane Wild
OBJECTIVE: To investigate the impact of antiepileptic drug (AED) change and dose titration on the emotional well-being of patients with epilepsy. METHODS: Members of an online epilepsy community were invited to voluntarily participate in an online survey. The cross-sectional anonymous survey consisted of 31 multiple choice questions balanced in terms of variety and positivity/negativity of emotions concerning participants' most recent AED change. To substantiate survey results, spontaneous comments from epilepsy-related online forums and social media websites that mentioned participants' experiences with AED medication changes (termed passive listening statements) were analyzed and categorized by theme...
February 18, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28222340/a-comparative-retrospective-exploration-of-the-profiles-of-patients-in-south-africa-diagnosed-with-epileptic-and-psychogenic-non-epileptic-seizures
#2
David G Anderson, Maria Damianova, Skye Hanekom, Marilyn Lucas
Psychogenic non-epileptic seizures (PNES) have a high prevalence globally but the accurate diagnosis of this condition still remains a challenge. This is particularly the case in countries where there is scarce expertise and insufficient affordable medical facilities to which patients have access. The rate of PNES diagnosis in epilepsy units is typically within the range of 20 to 30%. In the context of developing countries, this rate tends to be higher and increases demand on the existing scarce health care capacities...
February 18, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28222339/everyday-memory-impairment-in-patients-with-temporal-lobe-epilepsy-caused-by-hippocampal-sclerosis
#3
Patrícia Rzezak, Ellen Marise Lima, Ana Carolina Gargaro, Erica Coimbra, Silvia de Vincentiis, Tonicarlo Rodrigues Velasco, João Pereira Leite, Geraldo F Busatto, Kette D Valente
OBJECTIVE: Patients with temporal lobe epilepsy caused by hippocampal sclerosis (TLE-HS) have episodic memory impairment. Memory has rarely been evaluated using an ecologic measure, even though performance on these tests is more related to patients' memory complaints. We aimed to measure everyday memory of patients with TLE-HS to age- and gender-matched controls. METHODS: We evaluated 31 patients with TLE-HS and 34 healthy controls, without epilepsy and psychiatric disorders, using the Rivermead Behavioral Memory Test (RBMT), Visual Reproduction (WMS-III) and Logical Memory (WMS-III)...
February 18, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28222338/effect-of-synaptic-adhesion-like-molecule-3-on-epileptic-seizures-evidence-from-animal-models
#4
Jie Li, Ling Chen, Na Wang, Guohui Jiang, Yuqing Wu, Yi Zhang
Axonal sprouting and synaptic reorganization are the primary pathophysiological characteristics of epilepsy. Recent studies demonstrated that synaptic adhesion-like molecule 3 (SALM3) is highly expressed in the central nervous system and plays important roles in neurite outgrowth, branching, and axon guidance, mechanisms that are also observed in epilepsy. However, the expression of SALM3 in the epileptic brain and the effect of SALM3 in the pathogenesis of epilepsy remain unclear. The aims of this study were to investigate SALM3 expression in rat models of epilepsy and to explore the functional significance of SALM3 in epilepsy...
February 17, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28219054/frequency-and-factors-associated-with-emergency-department-attendance-for-people-with-epilepsy-in-a-rural-uk-population
#5
Jon Allard, Rohit Shankar, William Henley, Andrew Brown, Brendan McLean, Mark Jadav, Mary Parrett, Richard Laugharne, Adam J Noble, Leone Ridsdale
Attendance at UK Emergency Departments (EDs) for people with epilepsy (PWE) following a seizure can be unnecessary and costly. The characteristics of PWE attending a UK rural district ED in a 12-month period were examined to foster better understanding of relevant psycho-social factors associated with ED use by conducting cross-sectional interviews using standardized questionnaires. Of the total participants (n=46), approximately one-third of the study cohort attended ED on three or more occasions in the 12-month study period and accounted for 65% of total ED attendances reported...
February 17, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28219044/understanding-the-self-management-skills-of-persons-with-epilepsy
#6
Ramon Edmundo D Bautista
PURPOSE: To determine whether the self-management skills of persons with epilepsy (PWE) vary across the different domains of the Epilepsy Self-Management Scale (ESMS). METHODS: 172 PWE completed a survey questionnaire as well as the ESMS. RESULTS: Using ANOVA with pairwise comparison, the mean item scores of the medication, seizure, and safety management subscales of the ESMS were significantly higher than the lifestyle and information management subscales (p<0...
February 17, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28219043/epilepsy-by-the-numbers-epilepsy-deaths-by-age-race-ethnicity-and-gender-in-the-united-states-significantly-increased-from-2005-to-2014
#7
Sujay F Greenlund, Janet B Croft, Rosemarie Kobau
To inform public health efforts to prevent epilepsy-related deaths, we used the Centers for Disease Control and Prevention Wide-ranging Online Data for Epidemiologic Research (WONDER; Wonder.cdc.gov) to examine any-listed epilepsy deaths for the period 2005-2014 by age groups (≤24, 25-44, 45-64, 65-84, ≥85years), sex, and race/ethnicity (non-Hispanic White, non-Hispanic African American, Hispanic, Asian/Pacific Islander, or American Indian/Alaska Native). Epilepsy deaths were defined by the International Classification of Diseases, Tenth Revision (ICD-10) codes G40...
February 17, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28219042/educational-video-and-story-as-effective-interventions-reducing-epilepsy-related-stigma-among-children
#8
Dana Brabcová, Jiří Kohout, Veronika Weberová, Vladimír Komárek
Stigma has been related to epilepsy since ancient times. Despite the importance of this issue, only a few interventions focusing on the reduction of epilepsy-related stigma may be found in the literature. Thus, the aim of this study is to evaluate the effectiveness of two interventions focused on the reduction of epilepsy-related stigma in children aged 9-11years. The first group of children involved in the study (n1=89) completed the 23-item Czech version of the SSE (Stigma Scale of Epilepsy) questionnaire and an 11-item multiple-choice knowledge test, then watched a video and completed the same questionnaire and test immediately after the intervention...
February 17, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28215998/photosensitivity-in-generalized-epilepsies
#9
REVIEW
Shervonne Poleon, Jerzy P Szaflarski
Photosensitivity, which is the hallmark of photosensitive epilepsy (PSE), is described as an abnormal EEG response to visual stimuli known as a photoparoxysmal response (PPR). The PPR is a well-recognized phenomenon, occurring in 2-14% of patients with epilepsy but its pathophysiology is not clearly understood. PPR is electrographically described as 2-5Hz spike, spike-wave, or slow wave complexes with frontal and paracentral prevalence. Diagnosis of PPR is confirmed using intermittent photic stimulation (IPS) as well as video monitoring...
February 16, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28215997/cannabinoids-and-epilepsy-introduction
#10
EDITORIAL
Jerzy P Szaflarski, Orrin Devinsky
No abstract text is available yet for this article.
February 16, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28214777/utility-of-long-term-video-eeg-monitoring-for-children-with-staring
#11
Anup D Patel, Babitha Haridas, Zachary M Grinspan, Jack Stevens
OBJECTIVE: Staring spells are a common reason for referral to overnight epilepsy monitoring unit (EMU) evaluation. However, inpatient EMU admissions are expensive and time consuming. This study determined what percentage of those referred for staring had a confirmed epileptic seizure on long-term video-EEG monitoring (LTM) and developed a scoring system to help prioritize which patients should undergo this procedure. METHODS: We performed a four-year retrospective chart review of all children at a tertiary pediatric hospital who received LTM (long-term monitoring) for the purposes of characterizing staring...
February 16, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28213317/developing-and-assessing-the-acceptability-of-an-epilepsy-first-aid-training-intervention-for-patients-who-visit-uk-emergency-departments-a-multi-method-study-of-patients-and-professionals
#12
Darlene A Snape, Myfanwy Morgan, Leone Ridsdale, Steve Goodacre, Anthony G Marson, Adam J Noble
Epilepsy affects around 1% of the UK population; 40% of whom experience two or more seizures annually. However, most Emergency Department (ED) visits by people with epilepsy (PWE) are clinically unnecessary. Evidence highlights that with correct training, seizures can be safely managed by patients and their families within the community. Arguably therefore, PWE who frequently visit the ED might benefit from a self-management intervention that improves their own and their families' confidence and ability in managing seizures...
February 14, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28213316/opportunities-for-epilepsy-outcomes-of-the-milken-institute-state-of-the-science-retreat
#13
Sonya B Dumanis, Ekemini A U Riley, LaTese Briggs, YooRi Kim, Erik Lontok, Danielle Salka, Melissa Stevens
The Milken Institute Center for Strategic Philanthropy has launched a Giving Smarter Program in Epilepsy to inform philanthropists on the state of the science for the epilepsy field, key challenges, and solutions to address them. As part of the program, the Milken Institute Center for Strategic Philanthropy hosted a retreat to identify strategic investments that would accelerate epilepsy research to ultimately improve care. The top three prioritized opportunities from the retreat were to 1) invest in data standards and analytical tool development, 2) support young investigators, and 3) promote cross-sector collaborations especially between basic scientists, preclinical researchers, clinicians, and patients...
February 14, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28213162/the-effect-of-lamotrigine-on-learning-in-mice-using-the-passive-avoidance-model
#14
Fatemeh Izadpanah, Fatemeh Arab, Amin Zarghami, Ali Bijani, Sohrab Kazemi, Ali Akbar Moghadamnia
INTRODUCTION: Lamotrigine (LTG) is an antiepileptic drug that inhibits the release of glutamate by blocking sodium channels. The present study was conducted to evaluate the effect of LTG in different stages of memory using a passive avoidance learning task in mice. METHODS: Male albino mice in the weight range 20-25g were used. They were divided into four groups (control group and three groups receiving various doses of LTG). LTG was given in three doses of 10, 25, and 50mg/kg as intraperitoneal (IP) injections...
February 14, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28202408/self-management-in-epilepsy-why-and-how-you-should-incorporate-self-management-in-your-practice
#15
Sandra L Helmers, Rosemarie Kobau, Martha Sajatovic, Barbara C Jobst, Michael Privitera, Orrin Devinsky, David Labiner, Cam Escoffery, Charles E Begley, Ross Shegog, Dilip Pandey, Robert T Fraser, Erica K Johnson, Nancy J Thompson, Keith J Horvath
No abstract text is available yet for this article.
February 12, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28202407/epilepsy-monitoring-the-patients-views-a-qualitative-study-based-on-kolcaba-s-comfort-theory
#16
Andrea Egger-Rainer, Eugen Trinka, Julia Höfler, Anna Maria Dieplinger
PURPOSE: The aim of this qualitative study was to determine which perception of personal comfort patients name in the context of their hospitalization in an Austrian Epilepsy Monitoring Unit (EMU). METHODS: Problem-centred interviews with twelve inpatients were conducted. Data analyses were done according to Mayring's qualitative content analyses following the technique of structuring-deductive category assignment. RESULTS: Patients experienced different kinds of comfort along with their hospitalization in the EMU...
February 12, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28202406/cannabis-cultivation-methodological-issues-for-obtaining-medical-grade-product
#17
REVIEW
Suman Chandra, Hemant Lata, Mahmoud A ElSohly, Larry A Walker, David Potter
As studies continue to reveal favorable findings for the use of cannabidiol in the management of childhood epilepsy syndromes and other disorders, best practices for the large-scale production of Cannabis are needed for timely product development and research purposes. The processes of two institutions with extensive experience in producing large-scale cannabidiol chemotype Cannabis crops-GW Pharmaceuticals and the University of Mississippi-are described, including breeding, indoor and outdoor growing, harvesting, and extraction methods...
February 12, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28199920/family-burden-child-disability-and-the-adjustment-of-mothers-caring-for-children-with-epilepsy-role-of-social-support-and-coping
#18
Jeffrey M Carlson, Paul A Miller
PURPOSE: This study was designed to contribute to the existing research on the coping behaviors, social support, and mental health outcomes in parents of children with epilepsy in the United States. METHODS: Participants included 152, predominantly Caucasian (89.5%), married (78.9%) women (95.4%). Via a web-based interface, mothers completed questionnaires assessing the impact of their child's disability on their family (i.e., severity of their child's disability, family burden, and personal stress), social resources (i...
February 12, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28196741/a-common-vision-and-the-power-of-collaboration-the-managing-epilepsy-well-network-mew
#19
EDITORIAL
Barbara C Jobst
No abstract text is available yet for this article.
February 11, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28193596/vegf-regulates-hippocampal-neurogenesis-and-reverses-cognitive-deficits-in-immature-rats-after-status-epilepticus-through-the-vegf-r2-signaling-pathway
#20
Wei Han, Xiaojie Song, Rong He, Tianyi Li, Li Cheng, Lingling Xie, Hengsheng Chen, Li Jiang
Epilepsy is the most common chronic disease in children, who exhibit a higher risk for status epilepticus (SE) than adults. Hippocampal neurogenesis is altered by epilepsy, particularly in the immature brain, which may influence cognitive development. Vascular endothelial growth factor (VEGF) represents an attractive target to modulate brain function at the neurovascular interface and is a double-edged sword in seizures. We used the lithium-pilocarpine-induced epilepsy model in immature Sprague-Dawley rats to study the effects of VEGF on hippocampal neurogenesis in the acute phase and on long-term cognitive behaviors in immature rats following status epilepticus (SE)...
February 10, 2017: Epilepsy & Behavior: E&B
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