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Epilepsy & Behavior: E&B

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https://www.readbyqxmd.com/read/28728046/advanced-morphological-neuroimaging-study-in-lateral-temporal-lobe-epilepsy-a-multicentric-study
#1
Roberta Vasta, Alessia Sarica, Francesca Bisulli, Giancarlo Di Gennaro, Alfredo D'Aniello, Jacopo C Difrancesco, Laura Canafoglia, Marina Casazza, Silvana Franceschetti, Carlotta Stipa, Paolo Tinuper, Laura Mumoli, Antonio Gambardella, Angelo Labate
Lateral temporal lobe epilepsy (lTLE) is a rare condition characterized by auditory auras or receptive aphasia, negative MRI, and relatively benign evolution. With the low number of cases in the world, our objective was to analyze a cohort of sporadic cases with lTLE (slTLE), in order to investigate possible cerebral morphological alterations. Forty patients with lTLE (34.93±12.08years of age) and 38 healthy controls (CTRL, 34.55±9.08years of age) were enrolled from four tertiary Italian epilepsy centers, which provided brain MRI T1-weighted images following a standard protocol for patients with epilepsy...
July 17, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28728045/postdiagnosis-neurological-care-for-patients-with-psychogenic-nonepileptic-spells-pnes
#2
Chloe E Hill, Hannah Schwartz, Nabila Dahodwala, Brian Litt, Kathryn A Davis
OBJECTIVE: This study investigated continuity of neurological care for patients discharged from the epilepsy monitoring unit (EMU) with a diagnosis of psychogenic nonepileptic spells (PNES). Because PNES are seizure-like episodes that cannot be explained by abnormal electrical brain activity, they are challenging for patients to understand and accept. Consequently, after diagnosis, patients commonly fail to start recommended psychotherapy and instead pursue redundant medical care. As consistent relationships with healthcare providers may help, we instituted standard follow-up for patients diagnosed with PNES...
July 17, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28715780/use-of-perampanel-in-children-and-adolescents-with-lennox-gastaut-syndrome
#3
Stéphane Auvin, Blandine Dozieres, Adina Ilea, Catherine Delanoë
AIM: Report the use of perampanel treatment in children with Lennox-Gastaut syndrome (LGS). METHOD: We conducted a prospective study of 13 LGS patients (seven male; mean age, 12.8years) treated with adjunctive perampanel therapy. Perampanel was initiated at 2mg/day and titrated to a median maximum dose of 6mg/day. RESULTS: After a mean follow-up duration of 10.8months (range, 1-24months), nine patients (69.2%) were responders (≥50% reduction in total seizure frequency) and nine (69...
July 14, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28709815/urgent-need-to-implement-transition-programs
#4
LETTER
Rima Nabbout
No abstract text is available yet for this article.
July 11, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28697467/smoking-prevalence-and-seizure-control-in-chinese-males-with-epilepsy
#5
Hui Gao, Josemir W Sander, Xudong Du, Jiani Chen, Cairong Zhu, Dong Zhou
Smoking has a negative effect on most diseases, yet it is under-investigated in people with epilepsy; thus its role is not clear in the general population with epilepsy. We performed a retrospective pilot study on males with epilepsy to determine the smoking rate and its relationship with seizure control using univariate analysis to calculate odds ratios (ORs) and also used a multi-variate logistic regression model. The smoking rate in our sample of 278 individuals was 25.5%, which is lower than the general Chinese population smoking rate among males of 52...
July 7, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28686907/factors-affecting-quality-of-life-in-hungarian-adults-with-epilepsy-a-comparison-of-four-psychiatric-instruments
#6
Daniella Kováts, Noémi Császár, József Haller, Vera Juhos, Viola Sallay, Judit Békés, Anna Kelemen, Dániel Fabó, György Rásonyi, András Folyovich, Tamás Kurimay
PURPOSE: We investigated the impact of 19 factors on life quality in Hungarian patients with epilepsy. Wellbeing was evaluated by several inventories to investigate the impact of factors in more detail. METHODS: A cross-sectional study was performed in 170 patients. Wellbeing was evaluated with the WHO-5 Well-being Index (WHOQOL-5), Diener Satisfaction with Life Scale (SwLS), and the Quality of Life in Epilepsy-31 Questionnaire (Qolie-31). We investigated their association with demographic characteristics, general health status, epilepsy, and its treatment...
July 4, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28686906/lamotrigine-serum-levels-ceiling-effect-in-people-with-epilepsy-in-remission
#7
Jennifer D'Anto, Wlodzimierz Wnuk, Andrea O Rossetti, Laurent A Decosterd, Thierry Buclin, Jan Novy
BACKGROUND: Antiepileptic drug titration in epilepsy remains mostly empirical. Since in practice seizure remission may be obtained with low doses, we aimed to determine whether patients in remission have lower lamotrigine levels than those with ongoing seizures. METHODS: Retrospective comparison of the distribution of lamotrigine levels among unselected patients in remission and with ongoing seizures. Remission was defined as 3 times the longuest interseizure interval and at least one year...
July 4, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28683344/age-related-sleep-nocturnal-tonic-and-tonic-clonic-seizure-clusters-are-underdiagnosed-in-patients-with-dravet-syndrome
#8
Emma Losito, Matthieu Kuchenbuch, Nicole Chemaly, Jacques Laschet, Catherine Chiron, Anna Kaminska, Rima Nabbout
OBJECTIVES: To describe the semiology and EEG characteristics of the age-related pattern of sleep/nocturnal (S/N) seizures in patients with Dravet Syndrome (DS). METHODS: We retrospectively analysed the clinical and EEG data of DS patients followed at our reference centre for Rare Epilepsies. We included patients aged two years and older who fulfilled clinical and EEG criteria of DS (ILAE 1989). Genetic testing for SCN1A was done in all, followed by PCDH19 if this was negative...
July 3, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28673685/controversies-in-the-treatment-of-seizures-associated-with-neurocysticercosis
#9
REVIEW
Gagandeep Singh, Ravina Sharma
Seizures are the commonest manifestation of brain parenchymal cysticercosis. In terms of pathophysiological basis and prognostic significance of the seizures, a distinction might be applied between viable cysts, solitary cysticercus granuloma and calcific cysticerci. A number of uncertainties shroud the management of seizures in people with neurocysticercosis (NCC). Although antihelminthic treatment is effective in eliminating viable cysts and possibly cysticercus granulomas, its effect on seizure outcome remains uncertain...
June 30, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28672217/do-people-with-epilepsy-have-a-different-lifestyle
#10
Clara Aguirre, Sonia Quintas, Ana María Ruiz-Tornero, Guadalupe Alemán, Ana Betariz Gago-Veiga, María de Toledo, Jose Vivancos
BACKGROUND: Epilepsy is one of the most common neurological diseases. Its high prevalence, economic relevance and impact on daily life make it crucial that we study this condition in further detail. Our study seeks to investigate whether the lifestyle of people diagnosed with epilepsy is different to that of people without epilepsy, in order to better understand our patients. METHODS: We designed and delivered a questionnaire about quality of life and daily habits to patients from our hospital's Epilepsy Unit...
June 30, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28668603/the-effects-of-temperament-and-character-traits-on-perceived-social-support-and-quality-of-life-in-patients-with-epilepsy
#11
Kadir Demirci, Seden Demirci, Esra Taşkıran, Süleyman Kutluhan
OBJECTIVES: This study aimed to investigate the effect of temperament and character traits on perceived social support and quality of life in patients with epilepsy (PWE). METHODS: Fifty-two PWE and 54 healthy controls were included in this study. Demographics and clinical data were recorded. Temperament and Character traits were investigated using Temperament and Character Inventory (TCI), Perceived Social Support was evaluated by Multidimensional Scale of Perceived Social Support Scale (MSPSS), and quality of life was assessed using a 36-Item Short-Form Health Survey (SF-36)...
June 29, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28667864/an-acidosis-sparing-ketogenic-ask-diet-to-improve-efficacy-and-reduce-adverse-effects-in-the-treatment-of-refractory-epilepsy
#12
REVIEW
Alan W C Yuen, Isabel A Walcutt, Josemir W Sander
Diets that increase production of ketone bodies to provide alternative fuel for the brain are evolving from the classic ketogenic diet for epilepsy devised nearly a century ago. The classic ketogenic diet and its more recent variants all appear to have similar efficacy with approximately 50% of users showing a greater than 50% seizure reduction. They all require significant medical and dietetic support, and there are tolerability issues. A review suggests that low-grade chronic metabolic acidosis associated with ketosis is likely to be an important contributor to the short term and long term adverse effects of ketogenic diets...
June 28, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28666587/improving-access-to-health-care-for-people-living-with-epilepsy
#13
EDITORIAL
Steven Owens
No abstract text is available yet for this article.
June 27, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28666586/dravet-syndrome-sudep-and-omega-3-fatty-acids-lessons-from-the-past-learning-of-the-present-and-perspectives-for-the-future
#14
LETTER
Fulvio A Scorza, Carla A Scorza, Kette D Valente
No abstract text is available yet for this article.
June 27, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28666249/systematic-review-and-meta-analysis-of-the-efficacy-of-different-exercise-programs-in-pilocarpine-induced-status-epilepticus-models
#15
REVIEW
Muneeb Iqbal, Md Saidur Rahman, Salman Zafar, Xin-Lin Chen, Jian-Xin Liu, Yong Liu
PURPOSE: To conduct a systematic review and meta-analysis of studies testing exercise in animal models of pilocarpine induced status epilepticus (SE) and to compare the efficacy of different training strategies used in those studies. METHODS: We searched 2 online databases (Pubmed and Web of Science) for studies analyzing the efficacy of different trainings in pilocarpine-induced SE models. Training was categorized into forced physical training (PT), voluntary PT and resistance PT...
June 27, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28666184/pregnancy-outcome-in-women-with-epilepsy-in-western-china-a-prospective-hospital-based-study
#16
Shixu He, Huili Zhu, Xiangmiao Qiu, Xi Zhu, Anjiao Peng, Jianan Duan, Lei Chen
OBJECTIVE: Gaps exist in the diagnosis and treatment of women with epilepsy (WWE) between China and Euro-American countries. We aim to find out and share our experience of the multidisciplinary integrated treatment for WWE. METHODS: We prospectively registered WWE who were diagnosed by both epileptologists and obstetrician in our green way system for the past 5years (2009-2015). Registration information include years of education, epilepsy history, seizure type and frequency, pregnancy and delivery complications, delivery mode, and Apgar score of newborn...
June 27, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28662463/meg-language-lateralization-in-partial-epilepsy-using-dspm-of-auditory-event-related-fields
#17
Manoj Raghavan, Zhimin Li, Chad Carlson, Christopher T Anderson, Jeffrey Stout, David S Sabsevitz, Sara J Swanson, Jeffrey R Binder
OBJECTIVE: Methods employed to determine hemispheric language dominance using magnetoencephalography (MEG) have differed significantly across studies in the choice of language-task, the nature of the physiological response studied, recording hardware, and source modeling methods. Our goal was to determine whether an analysis based on distributed source modeling can replicate the results of prior studies that have used dipole-modeling of event-related fields (ERFs) generated by an auditory word-recognition task to determine language dominance in patients with epilepsy...
June 26, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28658654/post-traumatic-epilepsy-associations-with-mental-health-outcomes-in-the-first-two-years-after-moderate-to-severe-tbi-a-tbi-model-systems-analysis
#18
Shannon B Juengst, Amy K Wagner, Anne C Ritter, Jerzy P Szaflarski, William C Walker, Ross D Zafonte, Allen W Brown, Flora M Hammond, Mary Jo Pugh, Timothy Shea, Jason W Krellman, Tamara Bushnik, Patricia M Arenth
PURPOSE: Research suggests that there are reciprocal relationships between mental health (MH) disorders and epilepsy risk. However, MH relationships to post-traumatic epilepsy (PTE) have not been explored. Thus, the objective of this study was to assess associations between PTE and frequency of depression and/or anxiety in a cohort of individuals with moderate-to-severe TBI who received acute inpatient rehabilitation. METHODS: Multivariate regression models were developed using a recent (2010-2012) cohort (n=867 unique participants) from the TBI Model Systems (TBIMS) National Database, a time frame during which self-reported seizures, depression [Patient Health Questionnaire (PHQ)-9], and anxiety [Generalized Anxiety Disorder (GAD-7)] follow-up measures were concurrently collected at year-1 and year-2 after injury...
June 25, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28658653/perceived-need-for-restrictions-on-activity-for-children-with-epilepsy
#19
Paula M Brna, Kevin E Gordon, Elaine Woolridge, Joseph M Dooley, Ellen Wood
BACKGROUND: Children and youth with epilepsy have long been subjected to excessive restrictions on extracurricular activities due to concerns over risk of injury. Over time physicians and medical regulatory associations have liberalized the advice given for people with epilepsy to promote independence, self-esteem and general health benefits of physical activity. Current evidence suggests that few restrictions are needed for children with epilepsy beyond water-related precautions and avoidance of very high-risk activities...
June 25, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28654799/neurobehavioral-consequences-of-continuous-spike-and-waves-during-slow-sleep-csws-in-a-pediatric-population-a-pattern-of-developmental-hindrance
#20
Valentina De Giorgis, Melissa Filippini, Joyce Ann Macasaet, Silvia Masnada, Pierangelo Veggiotti
INTRODUCTION: Continuous spike and waves during slow sleep (CSWS) is a typical EEG pattern defined as diffuse, bilateral and recently also unilateral or focal localization spike-wave occurring in slow sleep or non-rapid eye movement sleep. Literature results so far point out a progressive deterioration and decline of intellectual functioning in CSWS patients, i.e. a loss of previously normally acquired skills, as well as persistent neurobehavioral disorders, beyond seizure and EEG control...
June 24, 2017: Epilepsy & Behavior: E&B
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