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Chinese Journal of Dental Research

Alicia González-Mourelle, Maria Pombo Castro, Inés Vázquez Mahía, Beatriz Patiño Seijas, José Luis López-Cedrún
Benign osteoblastoma is a rare bone tumour characterised histologically by the production of woven bone spicules, which are bordered by prominent osteoblasts. It mainly affects young adults. We report a rare case of benign osteoblastoma of the maxilla in a 7-year-old boy who presented with a painful swelling on the left hard palate. An incisional biopsy was interpreted as osteoblastic neoplasm most suggestive of osteoblastoma. After excision of the tumour there has been no recurrence for 2 years.
2018: Chinese Journal of Dental Research
Zeinab Rezaei Esfahrood, Sahar Vardian Tehrani, Zahra Yadegari, Bahareh Shams, Farshid Dehnavi, Nasim Shams
OBJECTIVE: To evaluate resistin levels in the saliva of patients with chronic periodontitis, and healthy subjects. METHODS: Thirty-four subjects aged between 25 and 50 years were included and divided into healthy group (n = 19) and chronic periodontitis group (n = 15). The saliva levels of resistin were assessed by enzyme-linked immunosorbent assay. Comparisons of resistin levels between the two groups were made with the Mann-Whitney Test. RESULTS: The chronic periodontitis group showed significantly higher resistin levels than the control group (P = 0...
2018: Chinese Journal of Dental Research
Jian Jiao, Jing Ren Zhao, Li Zhang, Dong Shi, Rui Fang Lu, Huan Xin Meng
OBJECTIVE: To explore associations between mean discrepancy values for the first and second molars (MDVFSs) and generalised aggressive periodontitis (GAgP) using hospital-based periodontal examination records from a large Chinese population. METHODS: Data from consecutive patients diagnosed as having chronic periodontitis (CP, n = 51,849) and GAgP (n = 2,706) were included. Patient ages, gender, smoking status, mean full-mouth probing depth (PD), and mean full-mouth attachment loss (AL), as well as MDVFSs for PD and AL, were extracted...
2018: Chinese Journal of Dental Research
Jin Ye Fu, Chen Ping Zhang, Jing Gao, Jian Feng Luo, Jiang Li, Jia Wei Zheng
OBJECTIVE: To evaluate the temporal trend of inpatients with smoking-associated oral cancer in Shanghai and its surrounding areas and to forecast the public health burden in the next decade. METHODS: Data of inpatients with oral cancer were retrieved from Shanghai Ninth People's Hospital during a 15-year period. The annual numbers of inpatients were compared by Chi-test. The hospitalization expenditures were compared by Student's t test. The trend analysis and inpatient forecasting were performed by exponential smoothing, regression models, and the forecasting function in Excel software...
2018: Chinese Journal of Dental Research
Hayes Wong, Brian E Cairns
OBJECTIVE: To investigate whether nerve growth factor (NGF) alters glutamate expression in sensory fibres and glutamate concentration in the masseter muscle of female rats. METHODS: Ten female rats were injected with NGF (25 µg/ml, 10 μl) and vehicle into the right and left masseter muscles, respectively. Immunohistochemistry and microdialysis were performed after 3 days to evaluate glutamate expression and concentration in the muscle. RESULTS: The frequency of expression of glutamate in the nerve fibres innervating the masseter muscle was significantly greater 3 days after NGF (56 ± 5%) than after vehicle (39 ± 5%) injection...
2018: Chinese Journal of Dental Research
Yingci Liu, Atsushi Arai, Terresa Kim, Sol Kim, No-Hee Park, Reuben H Kim
OBJECTIVE: To identify and verify the histone modifier during osteoclastogenesis. METHODS: Murine macrophage-like cell line, RAW 264.7 cells, or murine bone marrow macrophages (BMMs) were treated with a receptor activator of nuclear factor B ligand (RANKL) alone or RANKL with macrophage colony-stimulating factor (M-CSF), respectively, to induce differentiation of osteoclast. Quantitative real-time polymerase chain reaction (qRT-PCR) was used to screen different arrays of histone demethylases...
2018: Chinese Journal of Dental Research
Long Wei Lv, Yun Song Liu, Ping Zhang, Ming Gu, Xiang Song Bai, Chun Yang Xiong, Yong Sheng Zhou
OBJECTIVE: To explore graphene's effects on the gene expression profile of mesenchymal stem cells, and to reveal the mechanisms of graphene-guided osteogenic differentiation. METHODS: Human adipose-derived mesenchymal stem cells (hASCs) were cultured on single-layer graphene-coated titanium disks or titanium disks in proliferation medium (control) or osteoinduction medium for 7 days before RNA extraction. After library construction and RNA sequencing, identification of differentially expressed genes was performed through Limma package of R platform, with a cut-off value of log fold change (logFC) > = |1|...
2018: Chinese Journal of Dental Research
Yuan Zhu, Ping Zhang, Ran Li Gu, Yun Song Liu, Yong Sheng Zhou
Over the past few decades, scientific research into neural crest-derived stem cells has progressed rapidly. The migration and differentiation of neural crest-derived stem cells has been an interesting area of research. Stem cells within teeth originating from the embryonic neural crest have attracted increasing attention in clinical and scientific research because they are easy to obtain and have superb stemness. The stem cells within the teeth include dental pulp stem cells (DPSCs), dental follicle stem cells (DFSCs), stem cells from apical papilla (SCAPs), stem cells from human exfoliated deciduous teeth (SHEDs), and periodontal ligament stem cells (PDLSCs)...
2018: Chinese Journal of Dental Research
Jing Wang, Lu He
OBJECTIVE: To investigate the psychological condition of Chinese patients with or without a primary complaint of halitosis. METHODS: The psychological condition of 196 Chinese patients who visited the Department of Periodontics was evaluated using the Cornell Medical Index (CMI) health questionnaire. The breath malodour of all patients was scored using the organoleptic test (OLT). RESULTS: More than half of patients (53.1%) complaining of halitosis actually demonstrated pseudo-halitosis...
2018: Chinese Journal of Dental Research
Ichiro Ogura, Yoshihiko Sasaki, Takaaki Oda, Mikiko Sue, Kazuhide Hayama
OBJECTIVE: To assess the correlation between conventional magnetic resonance (MR) imaging and MR sialography of parotid glands with salivary gland scintigraphy in patients with Sjögren's syndrome. METHODS: A retrospective study was conducted on eight patients with Sjögren's syndrome who underwent MR imaging and salivary gland scintigraphy. Conventional MR imaging techniques, such as T1-weighted images (T1WI), T2-weighted images (T2WI), and short TI inversion recovery images (STIR) were used for changes of fat signal in the parotid gland, while the MR sialography were used for ducts dilation of the parotid gland...
2018: Chinese Journal of Dental Research
Lu Gao, Yan Gu, Feng Chen, Qing Wei Ma
OBJECTIVE: To develop standard experimental methods to minimise technical variance in matrix preparation for MALDI-TOF MS (matrix-assisted laser desorption/ionisation time-offlight) profiling. METHODS: Matrix factors in saliva and serum samples of 20 healthy volunteers were examined, assuring their peptide components using seven different matrix type/preparation methods, HCCA(a-cyano-4-hydroxycinnamic acid)/SM(sample/matrix), SA(sinapinic acid)/DD(dried droplet), SA/SM, DHB(2...
2018: Chinese Journal of Dental Research
Jia Qi Wu, Jiu Hui Jiang, Li Xu, Cheng Liang, Xiu Jing Wang, Yunyang Bai
OBJECTIVE: To identify a panel of differentially expressed candidate biomarkers for patients undergoing accelerated osteogenic orthodontics (AOO). METHODS: This study included 36 saliva samples taken from six Class III surgical patients at six time points: the date before the corticotomy procedure (T1) and at 1 week, 2 weeks, 1 month, 2 months and 6 months after the procedure (T2, T3, T4, T5 and T6, respectively). After the maxillary dental arch was aligned and levelled, AOO procedures were performed in the maxillary alveolar bone...
2018: Chinese Journal of Dental Research
Gang Chen, Ming Yan, Rong Rong Li, Wan Tao Chen
OBJECTIVE: To investigate the Sonic Hedgehog (SHH) signalling molecules and activated leukocyte cell adhesion molecule (ALCAM) expression in the mechanisms regulating invasion and metastasis in oral squamous cell carcinoma (OSCC). METHODS: The expressions of SHH signalling molecules Gli family zinc finger 1/2 (Gli1/Gli2), as well as ALCAM expression, was analysed in 101 OSCC patients by immunohistochemistry. The potential relationship between Gli1/Gli2 and ALCAM in regard to invasion and metastasis were studied by western blot, invasion and wound-healing assays...
2018: Chinese Journal of Dental Research
Atsuko Miyazawa, James Washington, Eve L Bingham, Shiuhyang Kuo, Stephen E Feinberg
OBJECTIVE: To develop a bioreactor for automated culture, maintenance, and collection of normal human keratinocytes using an enzyme-free propagation method. METHODS: The culture of normal human epithelial keratinocytes was compared in two culture methods - a study team-developed automated bioreactor utilising an enzyme-free passage method, and a manual culture method. Cell size, glucose utilisation, and the proliferative capacity of the two cultures were evaluated...
2018: Chinese Journal of Dental Research
Moon-Jong Kim, Hong-Seop Kho
Burning mouth syndrome (BMS) is a chronic pain condition characterised by a persistent burning sensation in clinically normal oral mucosa. BMS most commonly occurs in middleaged and elderly women. Various local and systemic factors can cause oral burning symptoms. When all possible local and systemic factors are excluded, burning mouth symptoms can be diagnosed as BMS. Psychophysical tests and histopathological data suggest the involvement of peripheral and central neuropathic mechanisms in BMS etiopathogenesis...
2018: Chinese Journal of Dental Research
Guangyan Yu
No abstract text is available yet for this article.
2018: Chinese Journal of Dental Research
Balamanikandasrinivasan Chandrasekaran, Nanditha Suresh, Senthilkumar Muthusamy
Supernumerary teeth are hyperdontic variants due to abnormalities during tooth development. Here, we report a case on regeneration of bony defect, which ensued following extraction of two supernumerary teeth in the mandibular premolar region, using a combination of bone grafts and platelet-rich fibrin. To the best of our knowledge, it is the first time synergistic use of biomaterials with bone grafts have been used for this type of management.
2017: Chinese Journal of Dental Research
Shi Yu Tian, Lin Tang, Chun Yan Zheng
OBJECTIVE: To investigate electric pulp test thresholds at different sites on healthy incisors and premolars and determine appropriate test sites. METHODS: Overall, 47 volunteers aged 20 to 30 years were recruited, and 163 incisors and 140 premolars were tested at several sites with an Electric Pulp Tester. One-way analysis of variance and a Tukey test were used to analyse the threshold values among different tooth types and sites. RESULTS: The lowest threshold value for incisors was identified on the incisal edge...
2017: Chinese Journal of Dental Research
Ichiro Ogura, Takaaki Oda, Mikiko Sue, Yoshihiko Sasaki, Kazuhide Hayama
OBJECTIVE: To assess the gallium-67 (67Ga) scintigraphy in differential diagnosis of malignant tumours from non-tumorous lesions of the maxilla. METHODS: Nineteen patients with malignant tumours (six cases of squamous cell carcinoma and one case of malignant melanoma) and non-tumorous lesions (seven cases of maxillary sinusitis and five cases of postoperative maxillary changes) in the maxilla underwent 67Ga and bone scintigraphy with CT and MRI. The statistical analysis with respect to comparison between imaging features of 67Ga and bone scintigraphy and maxillary lesions was performed with the Pearson's chi-squared test...
2017: Chinese Journal of Dental Research
Xian Zhou, Xiu Lian Hu, Jian Hui Li, Ye Lin
OBJECTIVE: To evaluate the effectiveness and clinical results of a new crestal sinus lift technique used to elevate the sinus floor simultaneously with bone grafts and implant placement. METHODS: Eleven patients underwent this crestal sinus lift technique performed using an SCA KIT. The mean residual bone height was 6.4 mm (range: 4.1 mm to 8.6 mm). Bio-Oss collagen was used as the graft material, and 12 implants were simultaneously placed after sinus augmentation...
2017: Chinese Journal of Dental Research
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