Read by QxMD icon Read

Nutritional Neuroscience

Andrew M Taylor, Hannah D Holscher
OBJECTIVE: Pre-clinical evidence suggests that the gastrointestinal microbiota contributes to mood and behavior disorders. Among humans, diet quality and patterns, which also impact the gastrointestinal microbiota, have been linked to depression, anxiety, and stress. This review summarizes findings from clinical studies using dietary intervention to improve depression, anxiety, or stress and the role the gastrointestinal microbiota may have in these disorders. METHODS: A literature search was conducted using the keywords microbiome, microbiota, depression, anxiety, stress, diet, dietary pattern, diet quality, fiber, prebiotics, probiotics, and mood...
July 9, 2018: Nutritional Neuroscience
Krystal Iacopetta, Lyndsey E Collins-Praino, Femke T A Buisman-Pijlman, Jiajun Liu, Amanda D Hutchinson, Mark R Hutchinson
BACKGROUND: The clinical and preclinical exploration of the therapeutic properties of vitamin D have significantly increased in the past decade, owing to the growing associative evidence suggesting vitamin D is neuroprotective. However, whether depletion of vitamin D contributes to the onset of neurological disorders or is a symptom of neurological disease has yet to be defined. Much remains unclear about the causal role of vitamin D and the method of use and forms of vitamin D. OBJECTIVES: We sought to quantitatively assess if neuroprotective benefits from vitamin D in neurodegenerative diseases are dependent on route of administration: comparing the effect of endogenously sourced vitamin D from UV exposure to exogenously derived vitamin D through synthetic supplementation...
July 9, 2018: Nutritional Neuroscience
Júlia Varga, Nikolett Petra Dér, Nóra Zsindely, László Bodai
OBJECTIVES: Green tea infusion contains a complex mixture of polyphenolic compounds that were shown to provide health benefits. It was previously demonstrated that (-)-epigallocatechin-3-gallate, one of the major polyphenols present in green tea, has a suppressing effect on various aspects of pathogenesis in models of Huntington's disease (HD), an inherited neurodegenerative disorder. In this study, we aimed to investigate, whether green tea infusion prepared as for human consumption has similar positive effects...
July 4, 2018: Nutritional Neuroscience
(no author information available yet)
No abstract text is available yet for this article.
July 2, 2018: Nutritional Neuroscience
Betul Kisioglu, Reyhan Nergiz-Unal
The influence of HFCS (high fructose corn syrup - free fructose) and sucrose (bound fructose) on fetal appetite signals is unknown. This study aimed to determine the effects of HFCS or sucrose on the peptide-mediated appetite regulation in fetal programming of obesity. Sprague Dawley female rats were administered feed and plain water (control) or water containing maltodextrin (vehicle), sucrose, fructose, or HFCS (20%, w/v) for 12 weeks before mating and throughout pregnancy and lactation (ndams = 31; npups = 207)...
July 1, 2018: Nutritional Neuroscience
Michael Munroe, Ziad S Mahmassani, Svyatoslav Dvoretskiy, Justin J Reid, Benjamin F Miller, Karyn Hamilton, Justin S Rhodes, Marni D Boppart
β-hydroxy β-methylbutyrate (HMB) is a nutritional supplement purported to enhance skeletal muscle mass and strength, as well as cognitive function in older adults. The purpose of this study was to determine the potential for long-term HMB supplementation to preserve muscle function and cognition in aged mice, as well as provide evidence of a link between vessel-associated pericyte function and outcomes. Four- (Adult/Ad) and 17 month-old (Aged/Ag) C57BL/6J mice consumed chow containing 600 mg/kg BW/day of either Ca-HMB (Ad, n=16; Ag, n=17) or Ca-Lactate (Ad, n=16; Ag, n=17) for 6 months...
June 19, 2018: Nutritional Neuroscience
Mantzorou Maria, Vadikolias Konstantinos, Pavlidou Eleni, Serdari Aspasia, Vasios Georgios, Tryfonos Christina, Giaginis Constantinos
INTRODUCTION: Cognitive impairment and malnutrition are two important public health issues in the elderly, which have been associated with their mental health. AIMS: This study aims to evaluate the nutritional status of an elderly population in Greece, and its association with the grade of cognitive decline, anthropometric measures and psychological status. MATERIALS AND METHODS: A total of 2092 elderly men and women were enrolled from seven Greek cities...
June 19, 2018: Nutritional Neuroscience
Fahimeh Haghighatdoost, Awat Feizi, Ahmad Esmaeilzadeh, Ammar Hassanzadeh Keshteli, Hamidreza Roohafza, Hamid Afshar, Peyman Adibi
OBJECTIVE: Although dietary patterns have been evaluated in relation to psychological disorders, their associations with psychosomatic complaints are unclear. We investigated relations of dietary patterns with psychosomatic complaints profiles. METHODS: In this cross-sectional study, a total of 3363 adults were included. Dietary intakes and psychosomatic complaints were assessed using self-administered Persian validated questionnaires. Dietary patterns and psychosomatic symptom profiles were identified using exploratory factor analysis...
June 18, 2018: Nutritional Neuroscience
Gabriela Vera-Rivera, María-Isabel Miranda, José Alejandro Rangel-Hernández, Dennys Badillo-Juárez, Daniela Fregoso-Urrutia, Seraid Caynas-Rojas
Food palatability and caloric content are crucial factors in guiding diet choice and amount consumed; as a result, sweet caloric tastes are associated with a positive hedonic value. Recent evidence in rodents indicates that consumption of artificial (non-caloric) sweeteners, in which sweet taste is dissociated from normal caloric consequences, could induce changes in energy and body weight regulation, suggesting that sweeteners not only modify intake and appetitive behavior, but could also change taste-learning processes...
June 4, 2018: Nutritional Neuroscience
Heloísa Mirelle Costa Monteiro, Débora Carneiro de Mendonça, Mariana Séfora Bezerra Sousa, Angela Amancio-Dos-Santos
OBJECTIVES: This investigation studied whether physical exercise could modulate cortical spreading depression (CSD) propagation velocity in adult rat offspring from dams that had received a high-fat (HF) diet during lactation. METHODS: Wistar male rats suckled by dams fed either control (C) or HF diet ad libitum. After weaning, pups received standard laboratory chow. From 40 to 60 days of life, half of the animals exercised on a treadmill (group E); the other half remained sedentary (group S)...
June 1, 2018: Nutritional Neuroscience
Neil Victor Yang, Emanuela Pannia, Diptendu Chatterjee, Ruslan Kubant, Mandy Ho, Rola Hammoud, Zdenka Pausova, G Harvey Anderson
BACKGROUND: Folic acid plays an important role in early brain development of offspring, including proliferation and differentiation of neural stem cells known to impact the function of food intake regulatory pathways. Excess (10-fold) intakes of folic acid in the gestational diet have been linked to increased food intake and obesity in male rat offspring post-weaning. OBJECTIVE: The present study examined the effects of folic acid content in gestational diets on the development and function of two hypothalamic neuronal populations, neuropeptide Y (NPY) and pro-opiomelanocortin (POMC), within food intake regulatory pathways of male Wistar rat offspring at birth and post-weaning...
May 30, 2018: Nutritional Neuroscience
Caitlin O B Yolland, Andrea Phillipou, David J Castle, Erica Neill, Matthew E Hughes, Cherrie Galletly, Zoe M Smith, Paul S Francis, Olivia M Dean, Jerome Sarris, Dan Siskind, Anthony W F Harris, Susan L Rossell
OBJECTIVES: Schizophrenia is a debilitating psychiatric illness associated with positive and negative symptoms as well as significant impairments in cognition. Current antipsychotic medications do not alleviate these cognitive deficits, and more effective therapeutic options are required. Increased oxidative stress and altered antioxidant levels, including glutathione (GSH) have been observed both in individuals with cognitive impairment and in people with schizophrenia. A GSH precursor, the antioxidant N-acetylcysteine (NAC) has been investigated as a novel treatment for the cognitive symptoms of schizophrenia, and recent research suggests that NAC may be a promising adjunctive treatment option...
May 30, 2018: Nutritional Neuroscience
Pallavi Sharma, Supriya Sharma, Damanpreet Singh
OBJECTIVES: Apigenin is the most common bioflavonoid known to be biologically active after systemic administration and show multiple pharmacological effects. The present study was designed to explore the role of apigenin in pentylenetetrazole (PTZ) kindling associated cognitive and behavioural impairments in the mouse model. METHODS: The animals were kindled by injecting a sub-convulsive dose of PTZ (35 mg/kg) on every alternate day, followed by 20 days treatment with apigenin at two different doses (10 and 20 mg/kg)...
May 30, 2018: Nutritional Neuroscience
A M van Opstal, A Hafkemeijer, A A van den Berg-Huysmans, M Hoeksma, C Blonk, H Pijl, S A R B Rombouts, J van der Grond
OBJECTIVES: The regulatory role of the brain in directing eating behavior becomes increasingly recognized. Although many areas in the brain have been found to respond to food cues, very little data is available after actual caloric intake. The aim of this study was to determine normal whole brain functional responses to ingestion of glucose after an overnight fast. METHODS: Twenty-five normal weight, adult males underwent functional MRI on two separate visits. In a single-blind randomized study setup, participants received either glucose solution (50 g/300 ml of water) or plain water...
May 27, 2018: Nutritional Neuroscience
Pei-Yu Wu, Mei-Yu Lin, Pei-Shan Tsai
OBJECTIVE: The alternate healthy eating index has been associated with depression. However, results reported in the literature are inconsistent. The present meta-analysis determined the association between the AHEI or AHEI-2010 and depression in adults without chronic disease. METHODS: Nine electronic databases and the reference lists of identified studies were systematically searched for studies published up to December 2016. Articles examining the association between depression and the AHEI or AHEI-2010 in adults were included...
May 27, 2018: Nutritional Neuroscience
Eliana Regina Louzada, Sandra Maria Lima Ribeiro
OBJECTIVES: We aimed to investigate the effect of a symbiotic substance on symptoms of brain disorders and inflammation in the elderly. METHODS: Forty-nine elders, both genders, assigned into two groups: S-group (synbiotic) and P-group (placebo). Evaluations at the beginning and at the end of the experiment: geriatric depressive symptoms scale-15 (GDS-15); mini-mental status examination (MMSE); % of body fat (%fat); serum IL-6, TNF-α and IL-10; serum diamine-oxidase (DAO), intestinal fatty-acid binding protein (IFABP), and lipopolysaccharide (LPS)...
May 23, 2018: Nutritional Neuroscience
Hai-Qiang Li, Long Tan, Hong-Peng Yang, Wei Pang, Tong Xu, Yu-Gang Jiang
OBJECTIVE: To examine protein changes in the hippocampus of APP/PS1 transgenic mice after blueberry extracts (BB) intervention. METHODS: Eight APP/PS1 transgenic mice were randomly assigned to Alzheimer's disease (AD)+BB group (n=4) and AD+control group (n=4). After a 16-week treatment, 2-DE and MALDI-TOF-MS were used to compare the proteomic profiles of the hippocampus in the two groups and Western blot was used to confirm the important differentially expressed proteins...
May 21, 2018: Nutritional Neuroscience
Rosimar Costa Penido, Myriam Lima Isaac, Alexandre Batista Penido
INTRODUCTION: Protein-caloric malnutrition is a public health concern in certain areas of the Brazil. It can affect growth, the auditory nervous system development and, consequently, the cognition. This study compared the Brainstem Auditory Evoked Potential (BAEP) between malnourished and eutrophic children. METHODS: A total of 111 children, aged 0-60 months, were examined: 57 were malnourished, according to the World Health Organization criteria, and 54 were normo-nourished...
May 14, 2018: Nutritional Neuroscience
Christiane de M B Almeida Leite, Maria Eliana M Schieferdecker, Caroline Frehner, Renato P Munhoz, Tetsuo Ashizawa, Hélio A G Teive
BACKGROUND: Spinocerebellar ataxias (SCAs) are a group of neurodegenerative genetic diseases characterized by movement disorders that can affect nutritional status and body composition. This study sought to assess body composition in SCA3 and SCA10 patients. METHODS: Anthropometric assessments and bioelectric impedance analysis were performed in 46 SCA3 and SCA10 patients and 76 controls of both genders. RESULTS: Of the patients, 69.6% had SCA3 and 58...
May 7, 2018: Nutritional Neuroscience
Seyed-Ali Mostafavi, Ali Khaleghi, Mohammad Reza Mohammadi, Shahin Akhondzadeh
Non-invasive electrical stimulation of the brain has recently been extensively investigated to regulate food craving. However, the existing literature is controversial and there are some important questions which need to be addressed about clinical and technical factors contributing to efficacy of this method. A systematic search was performed in reliable scientific databases, and 15 eligible studies were identified. The pooled standardized mean differences for the effects of transcranial direct current stimulation (tDCS) on Visual Analogue Scale, energy intake and food craving questionnaire were -0...
May 7, 2018: Nutritional Neuroscience
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"