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Neurorehabilitation and Neural Repair

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https://www.readbyqxmd.com/read/29199503/smart-arm-training-with-outcome-triggered-electrical-stimulation-in-subacute-stroke-survivors-with-severe-arm-disability-a-randomized-controlled-trial
#1
Ruth N Barker, Kathryn S Hayward, Richard G Carson, David Lloyd, Sandra G Brauer
BACKGROUND: Stroke survivors with severe upper limb disability need opportunities to engage in task-oriented practice to achieve meaningful recovery. OBJECTIVE: To compare the effect of SMART Arm training, with or without outcome-triggered electrical stimulation to usual therapy, on arm function for stroke survivors with severe upper limb disability undergoing inpatient rehabilitation. METHODS: A prospective, multicenter, randomized controlled trial was conducted with 3 parallel groups, concealed allocation, assessor blinding and intention-to-treat analysis...
December 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29192535/prism-adaptation-in-rehabilitation-no-additional-effects-of-prism-adaptation-on-neglect-recovery-in-the-subacute-phase-poststroke-a-randomized-controlled-trial
#2
Antonia F Ten Brink, Johanna M A Visser-Meily, Martijn J Schut, Mirjam Kouwenhoven, Anja L H Eijsackers, Tanja C W Nijboer
BACKGROUND: Patients with neglect ignore or respond slower to contralesional stimuli. Neglect negatively influences independence in activities of daily living (ADL). Prism adaptation (PA) is one of the most frequently studied treatments, yet there is little evidence regarding positive effects on neglect behavior in ADL. OBJECTIVE: To assess whether PA in the subacute phase ameliorates neglect in situations of varying complexity. METHODS: A total of 70 neglect patients admitted for inpatient stroke rehabilitation received either PA or sham adaptation (SA) for 2 weeks, with full access to standard treatment...
November 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29192534/intensive-communicative-therapy-reduces-symptoms-of-depression-in-chronic-nonfluent-aphasia
#3
Bettina Mohr, Benjamin Stahl, Marcelo L Berthier, Friedemann Pulvermüller
BACKGROUND: Patients with brain lesions and resultant chronic aphasia frequently suffer from depression. However, no effective interventions are available to target neuropsychiatric symptoms in patients with aphasia who have severe language and communication deficits. OBJECTIVE: The present study aimed to investigate the efficacy of 2 different methods of speech and language therapy in reducing symptoms of depression in aphasia on the Beck Depression Inventory (BDI) using secondary analysis (BILAT-1 trial)...
November 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29153039/higher-anxiety-symptoms-predict-progressive-hippocampal-atrophy-in-the-chronic-stages-of-moderate-to-severe-traumatic-brain-injury
#4
Alex R Terpstra, Todd A Girard, Brenda Colella, Robin E A Green
BACKGROUND: In the chronic stages of moderate-severe traumatic brain injury (TBI), progressive hippocampal volume loss-continuing well after acute neurological insults have resolved-has now been well documented. Previous research in other populations suggests that elevated anxiety symptoms are associated with compromise to the medial temporal lobes. OBJECTIVE: To examine whether higher anxiety symptoms predict greater hippocampal volume loss in moderate-severe TBI...
November 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29145773/forced-use-of-the-paretic-leg-induced-by-a-constraint-force-applied-to-the-nonparetic-leg-in-individuals-poststroke-during-walking
#5
Chao-Jung Hsu, Janis Kim, Elliot J Roth, William Z Rymer, Ming Wu
BACKGROUND: Individuals with stroke usually show reduced muscle activities of the paretic leg and asymmetrical gait pattern during walking. OBJECTIVE: To determine whether applying a resistance force to the nonparetic leg would enhance the muscle activities of the paretic leg and improve the symmetry of spatiotemporal gait parameters in individuals with poststroke hemiparesis. METHODS: Fifteen individuals with chronic poststroke hemiparesis participated in this study...
November 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29139337/do-people-with-severe-traumatic-brain-injury-benefit-from-making-errors-a-randomized-controlled-trial-of-error-based-and-errorless-learning
#6
Tamara Ownsworth, Jennifer Fleming, Robyn Tate, Elizabeth Beadle, Janelle Griffin, Melissa Kendall, Julia Schmidt, Amanda Lane-Brown, Mathilde Chevignard, David H K Shum
BACKGROUND: Errorless learning (ELL) and error-based learning (EBL) are commonly used approaches to rehabilitation for people with traumatic brain injury (TBI). However, it is unknown whether making errors is beneficial in the learning process to promote skills generalization after severe TBI. OBJECTIVE: To compare the efficacy of ELL and EBL for improving skills generalization, self-awareness, behavioral competency, and psychosocial functioning after severe TBI...
November 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29130824/longitudinal-structural-and-functional-differences-between-proportional-and-poor-motor-recovery-after-stroke
#7
Adrian G Guggisberg, Pierre Nicolo, Leonardo G Cohen, Armin Schnider, Ethan R Buch
BACKGROUND: Evolution of motor function during the first months after stroke is stereotypically bifurcated, consisting of either recovery to about 70% of maximum possible improvement ("proportional recovery, PROP") or in little to no improvement ("poor recovery, POOR"). There is currently no evidence that any rehabilitation treatment will prevent POOR and favor PROP. OBJECTIVE: To perform a longitudinal and multimodal assessment of functional and structural changes in brain organization associated with PROP...
November 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29130805/rehabilitative-success-after-brain-trauma-by-augmenting-a-subtherapeutic-dose-of-environmental-enrichment-with-galantamine
#8
Patricia B de la Tremblaye, Jody L Wellcome, Benjamin Wells de Witt, Jeffrey P Cheng, Elizabeth R Skidmore, Corina O Bondi, Anthony E Kline
BACKGROUND: Environmental enrichment (EE) confers benefits after traumatic brain injury (TBI) when provided daily for > 6 hours, but not 2 or 4 hours, which more accurately reflects the daily amount of clinical rehabilitation. The lack of benefit with sub-therapeutic EE suggests that augmentation with galantamine (GAL), which enhances cognition after TBI, may be indicated to confer benefits. OBJECTIVE: To test the hypothesis that 2 and 4 hours of EE paired with GAL will provide benefits comparable to 24 hours of EE alone...
November 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29130396/upper-limb-coordination-in-individuals-with-stroke-poorly-defined-and-poorly-quantified
#9
Yosuke Tomita, Marcos R M Rodrigues, Mindy F Levin
BACKGROUND: The identification of deficits in interjoint coordination is important in order to better focus upper limb rehabilitative treatment after stroke. The majority of standardized clinical measures characterize endpoint performance, such as accuracy, speed, and smoothness, based on the assumption that endpoint performance reflects interjoint coordination, without measuring the underlying temporal and spatial sequences of joint recruitment directly. However, this assumption is questioned since improvements of endpoint performance can be achieved through different degrees of restitution or compensation of upper limb motor impairments based on the available kinematic redundancy of the system...
November 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29130382/less-affected-hand-function-in-children-with-hemiparetic-unilateral-cerebral-palsy-a-comparison-study-with-typically-developing-peers
#10
Tonya L Rich, Jeremiah S Menk, Kyle D Rudser, Timothy Feyma, Bernadette T Gillick
BACKGROUND: Neurorehabilitation interventions in children with unilateral cerebral palsy (UCP) target motor abilities in daily life yet deficits in hand skills persist. Limitations in the less-affected hand may affect overall bimanual hand skills. OBJECTIVE: To compare hand function, by timed motor performance on the Jebsen-Taylor Test of Hand Function (JTTHF) and grip strength of children with UCP to children with typical development (CTD), aged 8 to 18 years old...
November 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29090654/the-twist-algorithm-predicts-time-to-walking-independently-after-stroke
#11
Marie-Claire Smith, P Alan Barber, Cathy M Stinear
BACKGROUND AND OBJECTIVE: The likelihood of regaining independent walking after stroke is of concern to patients and their families and influences hospital discharge planning. The objective of this study was to explore factors that could be combined in an algorithm for predicting whether and when a patient will walk independently after stroke. METHODS: Adults with new lower limb weakness were recruited within 3 days of having a stroke. Clinical assessment, transcranial magnetic stimulation, and magnetic resonance imaging were completed 1 to 2 weeks poststroke...
October 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29082783/impairments-in-spatiotemporal-gait-adaptation-during-obstacle-navigation-in-huntington-s-disease
#12
Naznine Anwar, Izelle Labuschagne, Katrina Simpson, Luke Smith, Nellie Georgiou-Karistianis
BACKGROUND: Navigating obstacles whilst walking might be associated with poorer balance and a higher risk of falling in individuals with symptomatic Huntington's disease (symp-HD). However, this issue has not been investigated within the literature. OBJECTIVE: A unique obstacle navigation experiment was designed to examine adaptive gait patterns in order to identify spatiotemporal gait characteristics that might be associated with poorer balance and a higher risk of falling in symp-HD...
October 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29081250/effects-of-training-intensity-on-locomotor-performance-in-individuals-with-chronic-spinal-cord-injury-a-randomized-crossover-study
#13
Gabrielle Brazg, Meghan Fahey, Carey L Holleran, Mark Connolly, Jane Woodward, Patrick W Hennessy, Brian D Schmit, T George Hornby
BACKGROUND: Many physical interventions can improve locomotor function in individuals with motor incomplete spinal cord injury (iSCI), although the training parameters that maximize recovery are not clear. Previous studies in individuals with other neurologic injuries suggest the intensity of locomotor training (LT) may positively influence walking outcomes. However, the effects of intensity during training of individuals with iSCI have not been tested. OBJECTIVE: The purpose of this pilot, blinded-assessor randomized trial was to evaluate the effects of LT intensity on walking outcomes in individuals with iSCI...
October 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29072556/a-home-based-telerehabilitation-program-for-patients-with-stroke
#14
Lucy Dodakian, Alison L McKenzie, Vu Le, Jill See, Kristin Pearson-Fuhrhop, Erin Burke Quinlan, Robert J Zhou, Renee Augsberger, Xuan A Tran, Nizan Friedman, David J Reinkensmeyer, Steven C Cramer
BACKGROUND: Although rehabilitation therapy is commonly provided after stroke, many patients do not derive maximal benefit because of access, cost, and compliance. A telerehabilitation-based program may overcome these barriers. We designed, then evaluated a home-based telerehabilitation system in patients with chronic hemiparetic stroke. METHODS: Patients were 3 to 24 months poststroke with stable arm motor deficits. Each received 28 days of telerehabilitation using a system delivered to their home...
October 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29233072/improving-the-development-monitoring-and-reporting-of-stroke-rehabilitation-research-consensus-based-core-recommendations-from-the-stroke-recovery-and-rehabilitation-roundtable
#15
Marion F Walker, Tammy C Hoffmann, Marian C Brady, Catherine M Dean, Janice J Eng, Amanda J Farrin, Cynthia Felix, Anne Forster, Peter Langhorne, Elizabeth A Lynch, Kathryn A Radford, Katharina S Sunnerhagen, Caroline L Watkins
Recent reviews have demonstrated that the quality of stroke rehabilitation research has continued to improve over the last four decades but despite this progress, there are still many barriers in moving the field forward. Rigorous development, monitoring and complete reporting of interventions in stroke trials are essential in providing rehabilitation evidence that is robust, meaningful and implementable. An international partnership of stroke rehabilitation experts committed to develop consensus-based core recommendations with a remit of addressing the issues identified as limiting stroke rehabilitation research in the areas of developing, monitoring and reporting stroke rehabilitation interventions...
October 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29233071/biomarkers-of-stroke-recovery-consensus-based-core-recommendations-from-the-stroke-recovery-and-rehabilitation-roundtable
#16
Lara A Boyd, Kathryn S Hayward, Nick S Ward, Cathy M Stinear, Charlotte Rosso, Rebecca J Fisher, Alexandre R Carter, Alex P Leff, David A Copland, Leeanne M Carey, Leonardo G Cohen, D Michele Basso, Jane M Maguire, Steven C Cramer
The most difficult clinical questions in stroke rehabilitation are "What is this patient's potential for recovery?" and "What is the best rehabilitation strategy for this person, given her/his clinical profile?" Without answers to these questions, clinicians struggle to make decisions regarding the content and focus of therapy, and researchers design studies that inadvertently mix participants who have a high likelihood of responding with those who do not. Developing and implementing biomarkers that distinguish patient subgroups will help address these issues and unravel the factors important to the recovery process...
October 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29233070/editorial
#17
Randolph J Nudo
No abstract text is available yet for this article.
October 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28934920/agreed-definitions-and-a-shared-vision-for-new-standards-in-stroke-recovery-research-the-stroke-recovery-and-rehabilitation-roundtable-taskforce
#18
Julie Bernhardt, Kathryn S Hayward, Gert Kwakkel, Nick S Ward, Steven L Wolf, Karen Borschmann, John W Krakauer, Lara A Boyd, S Thomas Carmichael, Dale Corbett, Steven C Cramer
The first Stroke Recovery and Rehabilitation Roundtable established a game changing set of new standards for stroke recovery research. Common language and definitions were required to develop an agreed framework spanning the four working groups: translation of basic science, biomarkers of stroke recovery, measurement in clinical trials and intervention development and reporting. This paper outlines the working definitions established by our group and an agreed vision for accelerating progress in stroke recovery research...
September 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28934919/editorial
#19
Randolph J Nudo
No abstract text is available yet for this article.
September 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28934918/standardized-measurement-of-sensorimotor-recovery-in-stroke-trials-consensus-based-core-recommendations-from-the-stroke-recovery-and-rehabilitation-roundtable
#20
Gert Kwakkel, Natasha A Lannin, Karen Borschmann, Coralie English, Myzoon Ali, Leonid Churilov, Gustavo Saposnik, Carolee Winstein, Erwin E H van Wegen, Steven L Wolf, John W Krakauer, Julie Bernhardt
Finding, testing and demonstrating efficacy of new treatments for stroke recovery is a multifaceted challenge. We believe that to advance the field, neurorehabilitation trials need a conceptually rigorous starting framework. An essential first step is to agree on definitions of sensorimotor recovery and on measures consistent with these definitions. Such standardization would allow pooling of participant data across studies and institutions aiding meta-analyses of completed trials, more detailed exploration of recovery profiles of our patients and the generation of new hypotheses...
September 2017: Neurorehabilitation and Neural Repair
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