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Neurorehabilitation and Neural Repair

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https://www.readbyqxmd.com/read/28818006/the-role-of-the-bdnf-val66met-polymorphism-in-recovery-of-aphasia-after-stroke
#1
Riemke G A de Boer, Kerstin Spielmann, Majanka H Heijenbrok-Kal, Rick van der Vliet, Gerard M Ribbers, W Mieke E van de Sandt-Koenderman
BACKGROUND: Brain-derived neurotrophic factor (BDNF) is assumed to play a role in mediating neuroplasticity after stroke. Carriers of the function-limiting Val66Met (rs6265) single nucleotide polymorphism (SNP) may have a downregulation in BDNF secretion, which may lead to a poorer prognosis after stroke compared to noncarriers in motor learning and motor function recovery. The present study investigates whether this polymorphism may also affect the recovery of poststroke aphasia (ie, language impairment)...
August 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28786309/improved-walking-capacity-and-muscle-strength-after-functional-power-training-in-young-children-with-cerebral-palsy
#2
Liesbeth F van Vulpen, Sonja de Groot, Eugene Rameckers, Jules G Becher, Annet J Dallmeijer
BACKGROUND: Strength training programs for children with cerebral palsy (CP) showed inconclusive evidence for improving walking, despite improvements in strength. Recent studies have suggested that strength training with high movement velocity is more effective for improving walking than traditional resistance training. OBJECTIVE: The purpose of this study was to evaluate the effect of functional high-velocity resistance training (power-training) to improve muscle strength and walking capacity of children with CP...
August 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28786307/neuroplastic-changes-induced-by-cognitive-rehabilitation-in-traumatic-brain-injury-a-review
#3
Valentina Galetto, Katiuscia Sacco
BACKGROUND: Cognitive deficits are among the most disabling consequences of traumatic brain injury (TBI), leading to long-term outcomes and interfering with the individual's recovery. One of the most effective ways to reduce the impact of cognitive disturbance in everyday life is cognitive rehabilitation, which is based on the principles of brain neuroplasticity and restoration. Although there are many studies in the literature focusing on the effectiveness of cognitive interventions in reducing cognitive deficits following TBI, only a few of them focus on neural modifications induced by cognitive treatment...
August 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28786305/ten-meters-walking-speed-in-spinal-cord-injured-patients-does-speed-predict-who-walks-and-who-rolls
#4
Lysanne van Silfhout, Allard J F Hosman, Ronald H M A Bartels, Michael J R Edwards, Rainer Abel, Armin Curt, Henk van de Meent
BACKGROUND: Walking speed is assumed to be a key factor in regaining ambulation after spinal cord injury (SCI). However, from the literature it remains unclear which walking speed usually results in independent community ambulation. OBJECTIVE: The primary aim of this study was to determine at which walking speed SCI patients tend to walk in the community instead of using a wheelchair. The secondary aim was to investigate clinical conditions that favor independent ambulation in the community...
August 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28786303/lower-extremity-motor-impairments-in-ambulatory-chronic-hemiparetic-stroke-evidence-for-lower-extremity-weakness-and-abnormal-muscle-and-joint-torque-coupling-patterns
#5
Natalia Sánchez, Ana Maria Acosta, Roberto Lopez-Rosado, Arno H A Stienen, Julius P A Dewald
Although global movement abnormalities in the lower extremity poststroke have been studied, the expression of specific motor impairments such as weakness and abnormal muscle and joint torque coupling patterns have received less attention. We characterized changes in strength, muscle coactivation and associated joint torque couples in the paretic and nonparetic extremity of 15 participants with chronic poststroke hemiparesis (age 59.6 ± 15.2 years) compared with 8 age-matched controls. Participants performed isometric maximum torques in hip abduction, adduction, flexion and extension, knee flexion and extension, ankle dorsi- and plantarflexion and submaximal torques in hip extension and ankle plantarflexion...
August 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28758519/perturbation-during-treadmill-training-improves-dynamic-balance-and-gait-in-parkinson-s-disease-a-single-blind-randomized-controlled-pilot-trial
#6
Simon Steib, Sarah Klamroth, Heiko Gaßner, Cristian Pasluosta, Björn Eskofier, Jürgen Winkler, Jochen Klucken, Klaus Pfeifer
BACKGROUND: Gait and balance dysfunction are major symptoms in Parkinson's disease (PD). Treadmill training improves gait characteristics in this population but does not reflect the dynamic nature of controlling balance during ambulation in everyday life contexts. OBJECTIVE: To evaluate whether postural perturbations during treadmill walking lead to superior effects on gait and balance performance compared with standard treadmill training. METHODS: In this single-blind randomized controlled trial, 43 PD patients (Hoehn & Yahr stage 1-3...
July 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28741434/robot-applied-resistance-augments-the-effects-of-body-weight-supported-treadmill-training-on-stepping-and-synaptic-plasticity-in-a-rodent-model-of-spinal-cord-injury
#7
Erika Hinahon, Christina Estrada, Lin Tong, Deborah S Won, Ray D de Leon
BACKGROUND: The application of resistive forces has been used during body weight-supported treadmill training (BWSTT) to improve walking function after spinal cord injury (SCI). Whether this form of training actually augments the effects of BWSTT is not yet known. OBJECTIVE: To determine if robotic-applied resistance augments the effects of BWSTT using a controlled experimental design in a rodent model of SCI. METHODS: Spinally contused rats were treadmill trained using robotic resistance against horizontal (n = 9) or vertical (n = 8) hind limb movements...
July 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28691645/a-single-bout-of-high-intensity-interval-training-improves-motor-skill-retention-in-individuals-with-stroke
#8
Jean-Francois Nepveu, Alexander Thiel, Ada Tang, Joyce Fung, Jesper Lundbye-Jensen, Lara A Boyd, Marc Roig
BACKGROUND: One bout of high-intensity cardiovascular exercise performed immediately after practicing a motor skill promotes changes in the neuroplasticity of the motor cortex and facilitates motor learning in nondisabled individuals. OBJECTIVE: To determine if a bout of exercise performed at high intensity is sufficient to induce neuroplastic changes and improve motor skill retention in patients with chronic stroke. METHODS: Twenty-two patients with different levels of motor impairment were recruited...
July 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28691601/task-specific-and-functional-effects-of-speed-focused-elliptical-or-motor-assisted-cycle-training-in-children-with-bilateral-cerebral-palsy-randomized-clinical-trial
#9
Diane L Damiano, Christopher J Stanley, Laurie Ohlrich, Katharine E Alter
BACKGROUND: Locomotor training using treadmills or robotic devices is commonly utilized to improve gait in cerebral palsy (CP); however, effects are inconsistent and fail to exceed those of equally intense alternatives. Possible limitations of existing devices include fixed nonvariable rhythm and too much limb or body weight assistance. OBJECTIVE: To quantify and compare effectiveness of a motor-assisted cycle and a novel alternative, an elliptical, in CP to improve interlimb reciprocal coordination through intensive speed-focused leg training...
July 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28691582/the-next-step-in-understanding-impaired-reactive-balance-control-in-people-with-stroke-the-role-of-defective-early-automatic-postural-responses
#10
Digna de Kam, Jolanda M B Roelofs, Amber K B D Bruijnes, Alexander C H Geurts, Vivian Weerdesteyn
BACKGROUND AND OBJECTIVE: Postural muscle responses are often impaired after stroke. We aimed to identify the contribution of deficits in very early postural responses to poorer reactive balance capacity, with a particular focus on reactive stepping as a key strategy for avoiding falls. METHODS: A total of 34 chronic stroke survivors and 17 controls were subjected to translational balance perturbations in 4 directions. We identified the highest perturbation intensity that could be recovered without stepping (single stepping threshold [SST]) and with maximally 1 step (multiple stepping threshold [MST])...
July 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28675943/do-activity-level-outcome-measures-commonly-used-in-neurological-practice-assess-upper-limb-movement-quality
#11
Marika Demers, Mindy F Levin
BACKGROUND: Movement is described in terms of task-related end point characteristics in external space and movement quality (joint rotations in body space). Assessment of upper-limb (UL) movement quality can assist therapists in designing effective treatment approaches for retraining lost motor elements and provide more detailed measurements of UL motor improvements over time. OBJECTIVE: To determine the extent to which current activity level outcome measures used in neurological practice assess UL movement quality...
July 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28639486/estimated-prevalence-of-the-target-population-for-brain-computer-interface-neurotechnology-in-the-netherlands
#12
Elmar G M Pels, Erik J Aarnoutse, Nick F Ramsey, Mariska J Vansteensel
BACKGROUND: People who suffer from paralysis have difficulties participating in society. Particularly burdensome is the locked-in syndrome (LIS). LIS patients are not able to move and speak but are cognitively healthy. They rely on assistive technology to interact with the world and may benefit from neurotechnological advances. Optimal research and design of such aids requires a well-defined target population. However, the LIS population is poorly characterized and the number of patients in this condition is unknown...
June 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28803535/robotic-assistance-for-training-finger-movement-using-a-hebbian-model-a-randomized-controlled-trial
#13
Justin B Rowe, Vicky Chan, Morgan L Ingemanson, Steven C Cramer, Eric T Wolbrecht, David J Reinkensmeyer
BACKGROUND: Robots that physically assist movement are increasingly used in rehabilitation therapy after stroke, yet some studies suggest robotic assistance discourages effort and reduces motor learning. OBJECTIVE: To determine the therapeutic effects of high and low levels of robotic assistance during finger training. METHODS: We designed a protocol that varied the amount of robotic assistance while controlling the number, amplitude, and exerted effort of training movements...
August 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28803534/moving-rehabilitation-research-forward-developing-consensus-statements-for-rehabilitation-and-recovery-research
#14
Julie Bernhardt, Karen Borschmann, Lara Boyd, S Thomas Carmichael, Dale Corbett, Steven C Cramer, Tammy Hoffmann, Gert Kwakkel, Sean Savitz, Gustavo Saposnik, Marion Walker, Nick Ward
Stroke recovery is the next frontier in stroke medicine. While growth in rehabilitation and recovery research is exponential, a number of barriers hamper our ability to rapidly progress the field. Standardized terminology is absent in both animal and human research, methods are poorly described, recovery biomarkers are not well defined, and we lack consistent timeframes or measures to examine outcomes. Agreed methods and conventions for developing, monitoring, evaluating and reporting interventions directed at improving recovery are lacking, and current approaches are often not underpinned by biology...
August 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28803533/corrigendum
#15
(no author information available yet)
Kuczynski AM, Dukelow SP, Semerau JA, Kirton A. Robotic quantification of position sense in children with perinatal stroke. Neurorehabil Neural Repair. 2016;30:762-772. doi:10.1177/1545968315624781.
August 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28803532/in-memoriam
#16
Randolph J Nudo
No abstract text is available yet for this article.
August 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28803531/editorial
#17
Randolph J Nudo
No abstract text is available yet for this article.
August 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28803530/enhancing-the-alignment-of-the-preclinical-and-clinical-stroke-recovery-research-pipeline-consensus-based-core-recommendations-from-the-stroke-recovery-and-rehabilitation-roundtable-translational-working-group
#18
Dale Corbett, S Thomas Carmichael, Timothy H Murphy, Theresa A Jones, Martin E Schwab, Jukka Jolkkonen, Andrew N Clarkson, Numa Dancause, Tadeusz Weiloch, Heidi Johansen-Berg, Michael Nilsson, Louise D McCullough, Mary T Joy
Stroke recovery research involves distinct biological and clinical targets compared to the study of acute stroke. Guidelines are proposed for the pre-clinical modeling of stroke recovery and for the alignment of pre-clinical studies to clinical trials in stroke recovery.
August 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28691602/somatosensory-feedback-to-the-cheek-during-virtual-visual-feedback-therapy-enhances-pain-alleviation-for-phantom-arms
#19
Akimichi Ichinose, Yuko Sano, Michihiro Osumi, Masahiko Sumitani, Shin-Ichiro Kumagaya, Yasuo Kuniyoshi
BACKGROUND: Patients who suffer from phantom limb pain can perceive tactile stimuli applied to the cheek on their affected side as if it were coming from their phantom limb, a phenomenon called "referred sensation." OBJECTIVES: To investigate the analgesic effect produced by tactile feedback provided to the cheek during neurorehabilitation using visual feedback. METHODS: Nine participants with phantom upper limb pain performed virtual reality neurorehabilitation exercises in which they repeatedly touched a target object with a virtual representation of their affected limb...
August 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28612647/in-memoriam
#20
(no author information available yet)
No abstract text is available yet for this article.
July 2017: Neurorehabilitation and Neural Repair
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