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Neurorehabilitation and Neural Repair

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https://www.readbyqxmd.com/read/28691645/a-single-bout-of-high-intensity-interval-training-improves-motor-skill-retention-in-individuals-with-stroke
#1
Jean-Francois Nepveu, Alexander Thiel, Ada Tang, Joyce Fung, Jesper Lundbye-Jensen, Lara A Boyd, Marc Roig
BACKGROUND: One bout of high-intensity cardiovascular exercise performed immediately after practicing a motor skill promotes changes in the neuroplasticity of the motor cortex and facilitates motor learning in nondisabled individuals. OBJECTIVE: To determine if a bout of exercise performed at high intensity is sufficient to induce neuroplastic changes and improve motor skill retention in patients with chronic stroke. METHODS: Twenty-two patients with different levels of motor impairment were recruited...
July 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28691602/somatosensory-feedback-to-the-cheek-during-virtual-visual-feedback-therapy-enhances-pain-alleviation-for-phantom-arms
#2
Akimichi Ichinose, Yuko Sano, Michihiro Osumi, Masahiko Sumitani, Shin-Ichiro Kumagaya, Yasuo Kuniyoshi
BACKGROUND: Patients who suffer from phantom limb pain can perceive tactile stimuli applied to the cheek on their affected side as if it were coming from their phantom limb, a phenomenon called "referred sensation." OBJECTIVES: To investigate the analgesic effect produced by tactile feedback provided to the cheek during neurorehabilitation using visual feedback. METHODS: Nine participants with phantom upper limb pain performed virtual reality neurorehabilitation exercises in which they repeatedly touched a target object with a virtual representation of their affected limb...
July 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28691601/task-specific-and-functional-effects-of-speed-focused-elliptical-or-motor-assisted-cycle-training-in-children-with-bilateral-cerebral-palsy-randomized-clinical-trial
#3
Diane L Damiano, Christopher J Stanley, Laurie Ohlrich, Katharine E Alter
BACKGROUND: Locomotor training using treadmills or robotic devices is commonly utilized to improve gait in cerebral palsy (CP); however, effects are inconsistent and fail to exceed those of equally intense alternatives. Possible limitations of existing devices include fixed nonvariable rhythm and too much limb or body weight assistance. OBJECTIVE: To quantify and compare effectiveness of a motor-assisted cycle and a novel alternative, an elliptical, in CP to improve interlimb reciprocal coordination through intensive speed-focused leg training...
July 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28691582/the-next-step-in-understanding-impaired-reactive-balance-control-in-people-with-stroke-the-role-of-defective-early-automatic-postural-responses
#4
Digna de Kam, Jolanda M B Roelofs, Amber K B D Bruijnes, Alexander C H Geurts, Vivian Weerdesteyn
BACKGROUND AND OBJECTIVE: Postural muscle responses are often impaired after stroke. We aimed to identify the contribution of deficits in very early postural responses to poorer reactive balance capacity, with a particular focus on reactive stepping as a key strategy for avoiding falls. METHODS: A total of 34 chronic stroke survivors and 17 controls were subjected to translational balance perturbations in 4 directions. We identified the highest perturbation intensity that could be recovered without stepping (single stepping threshold [SST]) and with maximally 1 step (multiple stepping threshold [MST])...
July 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28675943/do-activity-level-outcome-measures-commonly-used-in-neurological-practice-assess-upper-limb-movement-quality
#5
Marika Demers, Mindy F Levin
BACKGROUND: Movement is described in terms of task-related end point characteristics in external space and movement quality (joint rotations in body space). Assessment of upper-limb (UL) movement quality can assist therapists in designing effective treatment approaches for retraining lost motor elements and provide more detailed measurements of UL motor improvements over time. OBJECTIVE: To determine the extent to which current activity level outcome measures used in neurological practice assess UL movement quality...
July 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28639486/estimated-prevalence-of-the-target-population-for-brain-computer-interface-neurotechnology-in-the-netherlands
#6
Elmar G M Pels, Erik J Aarnoutse, Nick F Ramsey, Mariska J Vansteensel
BACKGROUND: People who suffer from paralysis have difficulties participating in society. Particularly burdensome is the locked-in syndrome (LIS). LIS patients are not able to move and speak but are cognitively healthy. They rely on assistive technology to interact with the world and may benefit from neurotechnological advances. Optimal research and design of such aids requires a well-defined target population. However, the LIS population is poorly characterized and the number of patients in this condition is unknown...
June 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28612647/in-memoriam
#7
(no author information available yet)
No abstract text is available yet for this article.
July 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28604171/abnormal-eeg-responses-to-tms-during-the-cortical-silent-period-are-associated-with-hand-function-in-chronic-stroke
#8
Whitney A Gray, Jacqueline A Palmer, Steven L Wolf, Michael R Borich
BACKGROUND: Abnormal brain excitability influences recovery after stroke at which time a prolonged transcranial magnetic stimulation (TMS)-induced electromyographic silent period is thought to reflect abnormal inhibitory interneuron excitability. Cortical excitability can be probed directly during the silent period using concurrent electroencephalography (EEG) of TMS-evoked responses. OBJECTIVE: The primary study objectives were to characterize TMS-evoked cortical potentials (TEPs) using EEG and to investigate associations with persistent hand and arm motor dysfunction in individuals with chronic stroke...
July 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28595509/rehabilitation-for-individuals-with-genetic-degenerative-ataxia-a-systematic-review
#9
Sarah C Milne, Louise A Corben, Nellie Georgiou-Karistianis, Martin B Delatycki, Eppie M Yiu
BACKGROUND: Treatment of genetic degenerative ataxia is currently based on symptom management and maintenance of function. However, utilization of rehabilitation is limited due to a lack of evidence supporting its efficacy. OBJECTIVE: This systematic review evaluated rehabilitation interventions for individuals with genetic degenerative ataxia. In addition, long-term outcomes from rehabilitation and optimal duration and intensity of rehabilitation were examined...
July 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28587561/short-term-motor-learning-and-retention-during-visually-guided-walking-in-persons-with-multiple-sclerosis
#10
Kayla McGowan, Shaila M Gunn, Galina Vorobeychik, Daniel S Marigold
BACKGROUND: The ability to adapt, a form of short-term motor learning, and retain this adaptation, is essential for rehabilitation and for day-to-day living. Yet little research is available on this topic in persons with multiple sclerosis (PwMS), particularly in relation to complex walking tasks. OBJECTIVE: To determine the ability of PwMS to learn and retain a novel relationship between visual input and motor output-or visuomotor map-during visually guided walking...
July 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28587545/skilled-reach-performance-correlates-with-corpus-callosum-structural-integrity-in-individuals-with-mild-motor-impairment-after-stroke-a-preliminary-investigation
#11
Jill Campbell Stewart, Michael O'Donnell, Kaci Handlery, Carolee J Winstein
BACKGROUND: Recovery of arm function after stroke is often incomplete. An improved understanding of brain structure-motor behavior relationships is needed for the development of novel and targeted rehabilitation interventions. OBJECTIVE: To examine the relationship between skilled reach performance and the integrity of two putative white matter motor pathways, corticospinal tract and corpus callosum, after stroke. METHODS: Eleven individuals with chronic stroke (poststroke duration, mean 62...
July 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28583011/cognitive-training-and-noninvasive-brain-stimulation-for-cognition-in-parkinson-s-disease-a-meta-analysis
#12
Blake J Lawrence, Natalie Gasson, Romola S Bucks, Lakkhina Troeung, Andrea M Loftus
BACKGROUND: Many people with Parkinson's disease (PD) experience cognitive decline. It is not known whether cognitive training or noninvasive brain stimulation are effective at alleviating cognitive deficits in PD. OBJECTIVE: To examine cognitive training and non-invasive brain stimulation interventions for cognition in PD. METHODS: An extensive search was conducted of published and unpublished studies in online databases. Studies were selected if they were controlled trials examining standard (not individualized) or tailored (individualized) cognitive training, repetitive transcranial magnetic stimulation (rTMS), or transcranial direct current stimulation (tDCS) in PD, with outcomes measured by standardized neuropsychological tests...
July 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28454498/efficacy-of-citalopram-on-acute-ischemic-stroke-outcome-a-randomized-clinical-trial
#13
Daryoush Savadi Oskouie, Ehsan Sharifipour, Homayoun Sadeghi Bazargani, Mazyar Hashemilar, Masoud Nikanfar, Saeed Ghazanfari Amlashi, Zahra Abbaszade, Elyar Sadeghihokmabadi, Reza Rikhtegar, Samad E J Golzari
BACKGROUND AND PURPOSE: Ischemic stroke (IS) is one of the main causes of death and disability in the adult population, and recovery from it is a major health concern worldwide. The aim of the present study was to evaluate the effectiveness of citalopram on 3-mounth outcome of nondepressed acute IS patients. METHODS: In a randomized, placebo-controlled clinical trial, 144 patients with acute IS were studied for 3 months. In one group, the patients received oral citalopram 20 mg (once daily), and in the other group, they received placebo...
July 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28506150/chronic-stroke-survivors-improve-reaching-accuracy-by-reducing-movement-variability-at-the-trained-movement-speed
#14
Ulrike Hammerbeck, Nada Yousif, Damon Hoad, Richard Greenwood, Jörn Diedrichsen, John C Rothwell
BACKGROUND: Recovery from stroke is often said to have "plateaued" after 6 to 12 months. Yet training can still improve performance even in the chronic phase. Here we investigate the biomechanics of accuracy improvements during a reaching task and test whether they are affected by the speed at which movements are practiced. METHOD: We trained 36 chronic stroke survivors (57.5 years, SD ± 11.5; 10 females) over 4 consecutive days to improve endpoint accuracy in an arm-reaching task (420 repetitions/day)...
June 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28506149/a-short-and-distinct-time-window-for-recovery-of-arm-motor-control-early-after-stroke-revealed-with-a-global-measure-of-trajectory-kinematics
#15
Juan C Cortes, Jeff Goldsmith, Michelle D Harran, Jing Xu, Nathan Kim, Heidi M Schambra, Andreas R Luft, Pablo Celnik, John W Krakauer, Tomoko Kitago
BACKGROUND: Studies demonstrate that most arm motor recovery occurs within three months after stroke, when measured with standard clinical scales. Improvements on these measures, however, reflect a combination of recovery in motor control, increases in strength, and acquisition of compensatory strategies. OBJECTIVE: To isolate and characterize the time course of recovery of arm motor control over the first year poststroke. METHODS: Longitudinal study of 18 participants with acute ischemic stroke...
June 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28506148/large-scale-phase-synchrony-reflects-clinical-status-after-stroke-an-eeg-study
#16
Teiji Kawano, Noriaki Hattori, Yutaka Uno, Keiichi Kitajo, Megumi Hatakenaka, Hajime Yagura, Hiroaki Fujimoto, Tomomi Yoshioka, Michiko Nagasako, Hironori Otomune, Ichiro Miyai
BACKGROUND AND PURPOSE: Stroke-induced focal brain lesions often exert remote effects via residual neural network activity. Electroencephalographic (EEG) techniques can assess neural network modifications after brain damage. Recently, EEG phase synchrony analyses have shown associations between the level of large-scale phase synchrony of brain activity and clinical symptoms; however, few reports have assessed such associations in stroke patients. OBJECTIVE: The aim of this study was to investigate the clinical relevance of hemispheric phase synchrony in stroke patients by calculating its correlation with clinical status...
June 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28506147/long-term-outcome-after-survival-of-a-cardiac-arrest-a-prospective-longitudinal-cohort-study
#17
Véronique R M Moulaert, Caroline M van Heugten, Ton P M Gorgels, Derick T Wade, Jeanine A Verbunt
BACKGROUND: A cardiac arrest can lead to hypoxic brain injury, which can affect all levels of functioning. OBJECTIVE: To investigate 1-year outcome and the pattern of recovery after surviving a cardiac arrest. METHODS: This was a multicenter, prospective longitudinal cohort study with 1 year of follow-up (measurements 2 weeks, 3 months, 1 year). On function level, physical/cardiac function (New York Heart Association Classification), cognition (Cognitive Log [Cog-log], Cognitive Failures Questionnaire), emotional functioning (Hospital Anxiety and Depression Scale, Impact of Event Scale), and fatigue (Fatigue Severity Scale) were assessed...
June 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28506146/the-impact-of-shoulder-abduction-loading-on-volitional-hand-opening-and-grasping-in-chronic-hemiparetic-stroke
#18
Yiyun Lan, Jun Yao, Julius P A Dewald
BACKGROUND: Up to 60% of individuals with moderate to severe chronic hemiparetic stroke experience excessive involuntary wrist/finger flexion that constrains functional hand movements including hand opening. It's not known how stroke-induced brain injury impacts volitional hand opening and grasping forces as a result of the expression of abnormal coupling between shoulder abduction and wrist/finger flexion or the flexion synergy. OBJECTIVE: The goal of this study is to understand how shoulder abduction loading affects volitional hand opening and grasping forces in individuals with moderate to severe chronic hemiparetic stroke...
June 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28337932/stroke-lesions-in-a-large-upper-limb-rehabilitation-trial-cohort-rarely-match-lesions-in-common-preclinical-models
#19
Matthew A Edwardson, Ximing Wang, Brent Liu, Li Ding, Christianne J Lane, Caron Park, Monica A Nelsen, Theresa A Jones, Steven L Wolf, Carolee J Winstein, Alexander W Dromerick
BACKGROUND: Stroke patients with mild-moderate upper extremity motor impairments and minimal sensory and cognitive deficits provide a useful model to study recovery and improve rehabilitation. Laboratory-based investigators use lesioning techniques for similar goals. OBJECTIVE: To determine whether stroke lesions in an upper extremity rehabilitation trial cohort match lesions from the preclinical stroke recovery models used to drive translational research. METHODS: Clinical neuroimages from 297 participants enrolled in the Interdisciplinary Comprehensive Arm Rehabilitation Evaluation (ICARE) study were reviewed...
June 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28413945/body-machine-interface-enables-people-with-cervical-spinal-cord-injury-to-control-devices-with-available-body-movements-proof-of-concept
#20
Farnaz Abdollahi, Ali Farshchiansadegh, Camilla Pierella, Ismael Seáñez-González, Elias Thorp, Mei-Hua Lee, Rajiv Ranganathan, Jessica Pedersen, David Chen, Elliot Roth, Maura Casadio, Ferdinando Mussa-Ivaldi
This study tested the use of a customized body-machine interface (BoMI) for enhancing functional capabilities in persons with cervical spinal cord injury (cSCI). The interface allows people with cSCI to operate external devices by reorganizing their residual movements. This was a proof-of-concept phase 0 interventional nonrandomized clinical trial. Eight cSCI participants wore a custom-made garment with motion sensors placed on the shoulders. Signals derived from the sensors controlled a computer cursor. A standard algorithm extracted the combinations of sensor signals that best captured each participant's capacity for controlling a computer cursor...
May 2017: Neurorehabilitation and Neural Repair
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