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Archives of Iranian Medicine

Amin Talebi Bezmin Abadi
No abstract text is available yet for this article.
June 1, 2018: Archives of Iranian Medicine
Atefeh Ghasemnejad, Ehsan Mostafavi
Dr. Ahmad Fayaz is one of the famous scientists in Iran in the field of rabies, and the most prominent person in controlling and prevention programs in the country in recent decades. One of his most important scientific achievements was introducing a new rabies vaccine produced in human diploid cell cultures to treat people exposed to rabies infection. Following that, anti-rabies serum therapy and injection of five doses of the cellular vaccine were entered into WHO protocol. Dr. Fayaz, as an expert and consultant of WHO, traveled to several countries and recommended appropriate ways to control rabies...
June 1, 2018: Archives of Iranian Medicine
Hadis Musavi, Hamideh Rahimi, Wesam Kooti, Ruhollah Dorostkar, Milad Azami, Maedeh Sharghi, Hadis Ashrafi-Zadeh, Mohammad Firoozbakht, Ramezan Ali Taheri
BACKGROUND: The probability of HIV transmission through contaminated blood and blood products is eye catching. 5%-10% of blood products are contaminated with HIV. Therefore, it is essential to provide safe blood supply to prevent transmission of infectious diseases. Current systematic review and meta-analysis was conducted to evaluate the weighted prevalence of HIV in Iranian blood donors. METHODS: This study was reported according to PRISMA checklist for systematic reviews and meta- analysis...
June 1, 2018: Archives of Iranian Medicine
Saffiyeh Saboormaleki, Hamid Sadeghian, Ahmad Reza Bahrami, Ala Orafaie, Maryam M Matin
BACKGROUND: Prostate cancer is one of the leading causes of cancer related deaths in males worldwide. Overexpression of 15-lipoxygenase-1 (15-LOX-1) enzyme and high activity of its metabolic pathway is reported to be a driver for prostate cancer malignancy. Farnesyloxycoumarin derivatives (3f, 4f and 7f) inhibit lipoxygenase enzyme. We hypothesized that farnesyloxycoumarins may exert an anti-cancer effect on prostate cancer cells due to their 15-LOX-1 inhibitory potential. METHODS: The enzyme inhibitory activity of 3f, 4f and 7f was initially evaluated on PC-3 and DU145 prostate cancer cell lines...
June 1, 2018: Archives of Iranian Medicine
Hamidreza Bahmani Bohloli, Soheil Nazarian, Majid Habibi, Mozhgan Fallahnia, Azam Zare, Ardeshir Bahmanimehr
BACKGROUND: Blood gas analysis is very important in the patients with respiratory problems. Arterial puncture may cause complications such as pain, local hematoma, infection and nerve injury. The procedure itself can be technically difficult. In contrast, venous sampling is an easier procedure with fewer complications. Therefore, this study aims to determine the possibility of replacement of venous blood gas (VBG) values by ABG values in ICU wards admitted patients. METHODS: In this study, 155 paired blood gas samples collected from patients admitted to ICU wards in Motahari hospital, Marvdasht, Fars, Iran...
June 1, 2018: Archives of Iranian Medicine
Kenan Erdem, Yilmaz Ozbay
BACKGROUND: Coronary artery anomalies (CAAs) include clinically and anatomically diverse types of congenital heart defects occurring in a complicated spectrum. The aim of the present study is to describe congenital anomalies of coronary arteries (CAs) and their variations, and also identify the prevalence of these anomalies in our center. METHODS: The study included a total of 6237 consecutive patients. Cine-angiographies and digital data of all patients undergoing coronary angiography (CAG) were reviewed by at least 2 independent and experienced observers...
June 1, 2018: Archives of Iranian Medicine
Hatice Ataş, Filiz Canpolat, Fatma Eskioglu
BACKGROUND: Patients with Behcet's disease (BD) are recognized with increased risk for venous and/or arterial thrombosis. Thrombotic tendency of BD is not known. Vascular injury, loss and dysfunction/hyperfunction of endothelial cells are believed to play a role in thrombosis development. Injury and inflammation due to vasculitis can cause platelet response with increase in mean platelet volume (MPV) and thrombosis in BD. In this study, we aimed to compare the levels of MPV between patients with BD and healthy controls, and also show its effect on thrombosis...
June 1, 2018: Archives of Iranian Medicine
Sahar Alimirzaie, Ashraf Mohamadkhani, Sahar Masoudi, Erin Sellars, Paolo Boffetta, Reza Malekzadeh, Mohammad R Akbari, Akram Pourshams
BACKGROUND: Pancreatic cancer is the fourth most common cause of mortality due to cancer, globally. It has a poor prognosis and is usually diagnosed at later stages when tumor resection is not possible. Heritability for pancreatic cancer is relatively high and clinically significant. METHODS: A group of 24 pancreatic cancer patients with young age at onset, from a referral hospital in Tehran University of Medical Sciences were screened for mutations in 710 cancer relevant genes using next generation sequencing technology...
June 1, 2018: Archives of Iranian Medicine
Rambod Mozafari, Ali Asadollahi-Amin
No abstract text is available yet for this article.
May 1, 2018: Archives of Iranian Medicine
Neslihan Çelik, Onur Çelik, Onur Ünal
Chickenpox, an infection of childhood with vesicular skin rash, is caused by varicella-zoster virus (VZV). Although the infection is rare in adults, it can cause serious complications Varicella pneumonia is the most encountered complication. In this report, a VZV pneumonia case in a previously healthy adult is presented. The patient was treated with early intravenous acyclovir and both clinical and radiographic recovery has been observed.
May 1, 2018: Archives of Iranian Medicine
Mehdi Javanbakht, Ahmad Reza Jamshidi, Hamid Reza Baradaran, Zahra Mohammadi, Atefeh Mashayekhi, Farhad Shokraneh, Mohsen Rezai Hamami, Raziyeh Yazdani Bakhsh, Hossien Shabaninejad, Sajad Delavari, Arash Tehrani
BACKGROUND: Recent evidence from prospective cohort studies show a relationship between consumption of dairy foods and cardiovascular diseases (CVDs) and type 2 diabetes mellitus (T2DM). This association highlights the importance of dairy foods consumption in prevention of these diseases and also reduction of associated healthcare costs. The aim of this study was to estimate avoidable healthcare costs of CVD and T2D through adequate dairy foods consumption in Iran. METHODS: This was a multistage modelling study...
May 1, 2018: Archives of Iranian Medicine
Kamal Dumaidi, Amer Al-Jawabreh
BACKGROUND: Pertussis caused by Bordetella pertussis is a vaccine-preventable disease causing whooping cough in humans of all ages. This study reports infection rate of pertussis in Palestine between the years 2004-2008 from archived nasopharyngeal samples collected from clinically- suspected cases. METHODS: A convenience archived DNA samples collected from 267 clinically-suspected pertussis cases were investigated for B. pertussis. Laboratory diagnosis was done by examining all DNA samples using polymerase chain reaction (PCR)...
May 1, 2018: Archives of Iranian Medicine
Arash Rashidian, Mohammad Arab, Mohammadreza Vaez Mahdavi, Koimars Ashtarian, Hakimeh Mostafavi
BACKGROUND: Health systems have a set of limited resources for meeting the needs of communities. Health priority setting based on criteria and values is inevitable in such situation. This paper aims to identify the social values that are considered in Iranian health system. METHODS: This qualitative study was conducted in 3 steps including collecting national documents and literature review, interviewing key informants, and a 2 round Delphi. Interviews and documents were analyzed through thematic framework analysis...
May 1, 2018: Archives of Iranian Medicine
Atefeh Tavakolian, Farideh Siavoshi, Fereshteh Eftekhar
BACKGROUND: Coexistence of bacteria and yeast in a myriad of microbial communities is indicative of their intimate relationship, which could be the intracellular existence of bacteria inside yeast. In this study, the intracellular existence of bacteria inside yeast and bacterial release from amphotericin B-treated yeasts was examined using polymerase chain reaction (PCR) and microscopy. METHODS: Released bacteria, B1 from Y1 (a gastric yeast) and B2 from Y2 (an oral yeast) were identified as Staphylococcus hominis and Staphylococcus haemolyticus by biochemical tests as well as amplification of Staph-specific tuf and 16S rRNA genes...
May 1, 2018: Archives of Iranian Medicine
Alale Roozdar, Malcolm M Hayes, Bahram Pourseyedei, Hamid Zeinalinejad, Manzumeh Shamsi Meymandi, Bahram Dabiri, Shahriar Dabiri
BACKGROUND: Gene expression profiling of breast cancer has demonstrated the importance of stromal response in determining the prognosis of invasive breast cancer. The host response to breast cancer is of increasing interest to pathologists and may be a future focus for novel pharmacological treatments. METHODS: This study describes the pattern of distribution of stromal myofibroblasts using immunostains for CD10 and smooth muscle actin (SMA) in 50 primary breast cancers and their matched nodal metastases (68...
May 1, 2018: Archives of Iranian Medicine
Mohammad Zamani, Reza Alizadeh-Navaei, Yadollah Zahed Pasha
No abstract text is available yet for this article.
April 1, 2018: Archives of Iranian Medicine
Masoud Behzadifar, Meysam Behzadifar, Nicola Luigi Bragazzi
No abstract text is available yet for this article.
April 1, 2018: Archives of Iranian Medicine
Houssem Harbi, Amine Chaabouni, Rim Kallel, Nozha Toumi, Sami Fendri, Jihene Krichene, Salah Boujelbene, Rafik Mzali
Isolated macro-nodular liver tuberculosis is a very rare condition. It may mimic primitive or secondary tumors of the liver. This could delay or mislead the therapeutic management. An immunocompetent 48-year-old man with a history of non-metastatic seminoma was treated with right orchidectomy followed by 20 Gy radiotherapy. The discovery, 8 months later, of a 2 cm nodule of the hepatic dome evoked a liver metastasis. Percutaneous biopsy was not feasible. Wedge resection was performed whereas medical treatment would have sufficed, as pathologic examination of the resected specimen showed a macro-nodular hepatic tuberculosis...
April 1, 2018: Archives of Iranian Medicine
Masoumeh Hosseini, Hossein Najmabadi, Kimia Kahrizi
Calpains are a group of non-lysosomal Ca2+ -dependent cysteine proteases with numerous substrates. Calpains have been identified in almost all eukaryotes and bacteria but not in archaebacteria. In the human genome, this group of enzymes has 15 isoforms and is present ubiquitously and demonstrates tissue-specific patterns of expression. Calpains are involved in different physiological and pathological processes such as cell proliferation, migration, invasion, apoptosis and signal transduction and their roles in various disorders have been reported...
April 1, 2018: Archives of Iranian Medicine
Amir Almasi-Hashiani, Saharnaz Nedjat, Mohammad Ali Mansournia
The goal of many observational studies is to estimate the causal effect of an exposure on an outcome after adjustment for confounders, but there are still some serious errors in adjusting confounders in clinical journals. Standard regression modeling (e.g., ordinary logistic regression) fails to estimate the average effect of exposure in total population in the presence of interaction between exposure and covariates, and also cannot adjust for time-varying confounding appropriately. Moreover, stepwise algorithms of the selection of confounders based on P values may miss important confounders and lead to bias in effect estimates...
April 1, 2018: Archives of Iranian Medicine
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