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Diabetes Technology & Therapeutics

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https://www.readbyqxmd.com/read/28541796/retraction-of-rt-mcgrath-et-al-evaluation-of-blood-glucose-meter-efficacy-in-an-antenatal-diabetes-clinic-diabetes-technol-ther-2016-18-2-68-74-doi-10-1089-dia-2015-0104
#1
(no author information available yet)
No abstract text is available yet for this article.
May 25, 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28537437/-it-is-definitely-a-game-changer-a-qualitative-study-of-experiences-with-in-home-overnight-closed-loop-technology-among-adults-with-type-1-diabetes
#2
Christel Hendrieckx, Lucinda A Poole, Amin Sharifi, Dilshani Jayawardene, Margaret M Loh, Jodie C Horsburgh, Leon A Bach, Peter G Colman, Kavita Kumareswaran, Alicia J Jenkins, Richard J MacIsaac, Glenn M Ward, Benyamin Grosman, Anirban Roy, David N O'Neal, Jane Speight
BACKGROUND: This qualitative study explored trial participants' experiences of four nights of in-home closed loop. METHODS: Sixteen adults with type 1 diabetes, who completed a randomized crossover trial, were interviewed after four consecutive nights of closed-loop. Interviews were audio recorded, transcribed, and analyzed with a coding framework developed to identify the main themes. RESULTS: Participants had a mean age of 42 ± 10 years, nine were women; mean diabetes duration was 27 ± 7 years, and all were using insulin pumps...
May 24, 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28537427/overnight-counter-regulatory-hormone-levels-and-next-day-glycemia-in-adults-with-type-1-diabetes-during-closed-loop-insulin-delivery-versus-sensor-augmented-pump-with-low-glucose-suspend
#3
Anneke Graf, Glenn M Ward, Sara Vogrin, Vijaya Sundararajan, Amin Sharifi, Martin I De Bock, Dilshani Jayawardene, Margaret M Loh, Jodie C Horsburgh, Carolyn L Berthold, Nirubasini Paramalingam, Leon A Bach, Peter G Colman, Elizabeth A Davis, Benyamin Grosman, Alicia J Jenkins, Kavita Kumareswaran, Natalie Kurtz, Andrew Kyoong, Richard J MacIsaac, Anirban Roy, Timothy W Jones, David N O'Neal
No abstract text is available yet for this article.
May 24, 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28530490/role-of-continuous-glucose-monitoring-in-clinical-trials-recommendations-on-reporting
#4
Oliver Schnell, Katharine Barnard, Richard Bergenstal, Emanuele Bosi, Satish Garg, Bruno Guerci, Thomas Haak, Irl B Hirsch, Linong Ji, Shashank R Joshi, Maarten Kamp, Lori Laffel, Mathieu Chantal, William H Polonsky, Frank Snoek, Philip Home
Thanks to significant improvements in the precision, accuracy, and usability of continuous glucose monitoring (CGM), its relevance in both ambulatory diabetes care and clinical research is increasing. In this study, we address the latter perspective and derive provisional reporting recommendations. CGM systems have been available since around the year 2000 and used primarily in people with type 1 diabetes. In contrast to self-measured glucose, CGM can provide continuous real-time measurement of glucose levels, alerts for hypoglycemia and hyperglycemia, and a detailed assessment of glycemic variability...
May 22, 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28463010/behavioral-patterns-and-associations-with-glucose-control-during-12-week-randomized-free-living-clinical-trial-of-day-and-night-hybrid-closed-loop-insulin-delivery-in-adults-with-type-1-diabetes
#5
Ali Emami, Malgorzata E Willinska, Hood Thabit, Lalantha Leelarathna, Sara Hartnell, Sibylle Dellweg, Carsten Benesch, Julia K Mader, Manuel Holzer, Harald Kojzar, Thomas R Pieber, Sabine Arnolds, Mark L Evans, Roman Hovorka
OBJECTIVES: We evaluated patterns of meal intake, insulin bolus delivery, and fingerstick glucose measurements during hybrid closed-loop and sensor-augmented pump (SAP) therapy, including associations with glucose control. METHODS: Data were retrospectively analyzed from pump-treated adults with type 1 diabetes who underwent, in random order, 12 weeks free-living closed-loop (n = 32) and 12 weeks SAP (n = 33) periods. We quantified daily patterns of main meals, snacks, prandial insulin boluses, correction boluses, and fingerstick glucose measurements by analyzing data recorded on the study glucometer and on study insulin pump...
May 2, 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28459617/outpatient-closed-loop-control-with-unannounced-moderate-exercise-in-adolescents-using-zone-model-predictive-control
#6
Lauren M Huyett, Trang T Ly, Gregory P Forlenza, Suzette Reuschel-DiVirgilio, Laurel H Messer, R Paul Wadwa, Ravi Gondhalekar, Francis J Doyle, Jordan E Pinsker, David M Maahs, Bruce A Buckingham, Eyal Dassau
BACKGROUND: The artificial pancreas (AP) has the potential to improve glycemic control in adolescents. This article presents the first evaluation in adolescents of the Zone Model Predictive Control and Health Monitoring System (ZMPC+HMS) AP algorithms, and their first evaluation in a supervised outpatient setting with frequent exercise. MATERIALS AND METHODS: Adolescents with type 1 diabetes underwent 3 days of closed-loop control (CLC) in a hotel setting with the ZMPC+HMS algorithms on the Diabetes Assistant platform...
May 1, 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28459603/closed-loop-control-of-postprandial-glycemia-using-an-insulin-on-board-limitation-through-continuous-action-on-glucose-target
#7
Paolo Rossetti, Carmen Quirós, Vanessa Moscardó, Anna Comas, Marga Giménez, F Javier Ampudia-Blasco, Fabián León, Eslam Montaser, Ignacio Conget, Jorge Bondia, Josep Vehí
BACKGROUND: Postprandial (PP) control remains a challenge for closed-loop (CL) systems. Few studies with inconsistent results have systematically investigated the PP period. OBJECTIVE: To compare a new CL algorithm with current pump therapy (open loop [OL]) in the PP glucose control in type 1 diabetes (T1D) subjects. METHODS: A crossover randomized study was performed in two centers. Twenty T1D subjects (F/M 13/7, age 40.7 ± 10.4 years, disease duration 22...
May 1, 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28300428/empa-s-new-clothes-the-untold-story-of-the-empa-reg-outcome-trial
#8
Aus Alzaid
It is no secret that the diabetes community has been yearning for good news for quite some time. One outstanding issue undermining effective diabetes management has been the lack of demonstrable effects of glycemic interventions on cardiovascular (CV) outcome in people with type 2 diabetes. This, however, seems to have changed recently after the publication of the Empa-Reg Outcome Trial. The study reported an impressive reduction in CV deaths that was observed within weeks of treatment with the diabetes agent, Empagliflozin...
March 16, 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28296467/comparison-of-insulin-pump-therapy-and-multiple-daily-injections-insulin-regimen-in-patients-with-type-1-diabetes-during-ramadan-fasting
#9
Reem Alamoudi, Maram Alsubaiee, Ali Alqarni, Yousef Saleh, Saleh Aljaser, Abdul Salam, Mohsen Eledrisi
INTRODUCTION: Fasting Ramadan carries a high risk for patients with type 1 diabetes (T1DM). Data on the optimum insulin regimen in these patients are limited. OBJECTIVES: To compare glucose profiles in patients with T1DM who use continuous subcutaneous insulin infusion (CSII) compared with those who use multiple daily injections (MDI) insulin regimen during Ramadan fast. The primary outcome was rates of hypoglycemia. Other outcomes included glycemic control, number of days needed to break fasting, and acute glycemic complications...
March 15, 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28541139/factory-calibrated-continuous-glucose-sensors-the-science-behind-the-technology
#10
Udo Hoss, Erwin Satrya Budiman
The use of commercially available continuous glucose monitors for diabetes management requires sensor calibrations, which until recently are exclusively performed by the patient. A new development is the implementation of factory calibration for subcutaneous glucose sensors, which eliminates the need for user calibrations and the associated blood glucose tests. Factory calibration means that the calibration process is part of the sensor manufacturing process and performed under controlled laboratory conditions...
May 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28541138/clinical-use-of-continuous-glucose-monitoring-in-pediatrics
#11
Rayhan A Lal, David M Maahs
No abstract text is available yet for this article.
May 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28541137/clinical-use-of-continuous-glucose-monitoring-in-adults-with-type-2-diabetes
#12
Anders L Carlson, Deborah M Mullen, Richard M Bergenstal
Hemoglobin A1c is an excellent population health measure for the risk of vascular complications in diabetes, while continuous glucose monitoring (CGM) is a tool to help personalize a diabetes treatment plan. The value of CGM in individuals with type 1 diabetes (T1D) has been well demonstrated when compared with utilizing self-monitoring of blood glucose (SMBG) to guide treatment decisions. CGM is a tool for patients and clinicians to visualize the important role that diet, exercise, stress management, and the appropriate selection of diabetes medications can have in managing type 2 diabetes (T2D)...
May 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28541136/metrics-beyond-hemoglobin-a1c-in-diabetes-management-time-in-range-hypoglycemia-and-other-parameters
#13
Lorena Alarcon-Casas Wright, Irl B Hirsch
We review clinical instances in which A1C should not be used and reflect on the use of other glucose metrics that can be used, in substitution of or in combination with A1C and SMBG, to tailor an individualized approach that will result in better outcomes and patient empowerment.
May 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28541135/clinical-use-of-professional-continuous-glucose-monitoring
#14
Eugene E Wright, James R Gavin
No abstract text is available yet for this article.
May 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28541134/clinical-implications-of-accuracy-measurements-of-continuous-glucose-sensors
#15
Timothy S Bailey
The accuracy of a continuous glucose monitor (CGM) now supports its use by persons with diabetes and clinicians caring for them. This article reviews measures of CGM accuracy, factors contributing to accuracy, comparative accuracy assessment, clinical implications of CGM sensor accuracy, and recent clinical trials that have demonstrated the utility of CGMs.
May 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28541133/flash-glucose-monitoring-the-future-is-here
#16
Satish K Garg, Halis Kaan Akturk
No abstract text is available yet for this article.
May 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28541132/how-can-we-realize-the-clinical-benefits-of-continuous-glucose-monitoring
#17
Ramzi A Ajjan
Controlling glycemia in diabetes remains key to prevent complications in this condition. However, glucose levels can undergo large fluctuations secondary to daily activities, consequently creating management difficulties. The current review summarizes the basics of glucose management in diabetes by addressing the main glycemic parameters. The advantages and limitation of HbA1c, the gold standard measure of glucose control, are discussed together with the clinical importance of hypoglycemia and glycemic variability...
May 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28541131/clinical-use-of-continuous-glucose-monitoring-in-adults-with-type-1-diabetes
#18
David Slattery, Pratik Choudhary
With the emphasis on intensive management of type 1 diabetes, data from studies support frequent monitoring of glucose levels to improve glycemic control and reduce glucose variability, which can be related to an increase in macro and microvascular complications. However, few perform capillary blood glucose that frequently. There are currently two available alternatives that this review will discuss, continuous glucose monitoring (CGM) and flash glucose monitoring. CGM has become an important diagnostic and therapeutic option in optimizing diabetes management...
May 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28520532/effectiveness-of-smartguard-technology-in-the-prevention-of-nocturnal-hypoglycemia-after-prolonged-physical-activity
#19
Lenka Petruzelkova, Klara Pickova, Zdenek Sumnik, Jan Soupal, Barbora Obermannova
BACKGROUND: The prevention of postexercise nocturnal hypoglycemia after prolonged physical activity using sensor-augmented pump (SAP) therapy with predictive low-glucose management (PLGM) has not been well studied. We conducted a study at a pediatric diabetes camp to determine whether a SAP with PLGM reduces the frequency of nocturnal hypoglycemia after prolonged physical activity more effectively than a SAP with a carbohydrate intake algorithm. METHODS: During a 1-week sport camp, 20 children (aged 10-13 years) with type 1 diabetes (T1D) managed by SAP therapy either with (n = 7) or without PLGM (n = 13) were studied...
May 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28520531/artificial-pancreas-in-young-children
#20
Rebecca A Ohman-Hanson, Gregory P Forlenza
No abstract text is available yet for this article.
May 2017: Diabetes Technology & Therapeutics
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