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Current Hypertension Reports

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https://www.readbyqxmd.com/read/30006901/the-effects-of-oral-taurine-on-resting-blood-pressure-in-humans-a-meta-analysis
#1
REVIEW
Mark Waldron, Stephen David Patterson, Jamie Tallent, Owen Jeffries
PURPOSE OF REVIEW: The aims of this meta-analysis were to investigate the effects of orally administered isolated taurine on resting systolic blood pressure (SBP) and diastolic blood pressure (DBP) in humans. RECENT FINDINGS: There is growing evidence that taurine deficiency is associated with hypertension and that oral supplementation can have antihypertensive effects in humans. However, these investigations have been conducted across a number of decades and populations and have not been collectively reviewed...
July 13, 2018: Current Hypertension Reports
https://www.readbyqxmd.com/read/29992526/an-overview-of-metabolic-phenotyping-in-blood-pressure-research
#2
REVIEW
Ioanna Tzoulaki, Aikaterini Iliou, Emmanuel Mikros, Paul Elliott
PURPOSE OF THE REVIEW: This review presents the analytical techniques, processing and analytical steps used in metabolomics phenotyping studies, as well as the main results from epidemiological studies on the associations between metabolites and high blood pressure. RECENT FINDINGS: A variety of metabolomic approaches have been applied to a range of epidemiological studies to uncover the pathophysiology of high blood pressure. Several pathways have been suggested in relation to blood pressure including the possible role of the gut microflora, inflammatory, oxidative stress, and lipid pathways...
July 10, 2018: Current Hypertension Reports
https://www.readbyqxmd.com/read/29992504/orexins-sleep-and-blood-pressure
#3
REVIEW
Mariusz Sieminski, Jacek Szypenbejl, Eemil Partinen
PURPOSE OF REVIEW: The aim of this review was to summarize collected data on the role of orexin and orexin neurons in the control of sleep and blood pressure. RECENT FINDINGS: Although orexins (hypocretins) have been known for only 20 years, an impressive amount of data is now available regarding their physiological role. Hypothalamic orexin neurons are responsible for the control of food intake and energy expenditure, motivation, circadian rhythm of sleep and wake, memory, cognitive functions, and the cardiovascular system...
July 10, 2018: Current Hypertension Reports
https://www.readbyqxmd.com/read/29992362/visceral-adipose-tissue-accumulation-and-residual-cardiovascular-risk
#4
REVIEW
Thierry H Le Jemtel, Rohan Samson, Gregory Milligan, Abhishek Jaiswal, Suzanne Oparil
PURPOSE OF THE REVIEW: Low-grade systemic inflammation increases residual cardiovascular risk. The pathogenesis of low-grade systemic inflammation is not well understood. RECENT FINDINGS: Visceral adipose tissue accumulates when the subcutaneous adipose tissue can no longer store excess nutrients. Visceral adipose tissue inflammation initially facilitates storage of nutrients but with time become maladaptive and responsible for low-grade systemic inflammation. Control of low-grade systemic inflammation requires reversal of visceral adipose tissue accumulation with intense and sustained aerobic exercise or bariatric surgery...
July 10, 2018: Current Hypertension Reports
https://www.readbyqxmd.com/read/29992361/the-role-of-uric-acid-in-preeclampsia-is-uric-acid-a-causative-factor-or-a-sign-of-preeclampsia
#5
REVIEW
Olive P Khaliq, Tadashi Konoshita, Jagidesa Moodley, Thajasvarie Naicker
PURPOSE OF REVIEW: Because of the significant discrepancies on this topic, this review will focus on the role of uric acid in PE, uric acid as a predictor of preeclampsia and fetal growth retardation. We considered eligible review and original articles relevant to the research question. RECENT FINDINGS: Hypertensive disorders of pregnancy such as preeclampsia (PE) are a major cause of both maternal and fetal morbidity and mortality worldwide. Uric acid has been reported as a key factor contributing to the pathogenesis of PE...
July 10, 2018: Current Hypertension Reports
https://www.readbyqxmd.com/read/29980951/potential-role-of-antihypertensive-medications-in-preventing-excessive-arterial-stiffening
#6
REVIEW
Guanghong Jia, Annayya R Aroor, Luis A Martinez-Lemus, James R Sowers
PURPOSE OF REVIEW: Increased arterial stiffness, an abnormal structural and functional change in the vascular wall, is a precursor for hypertension, coronary heart disease, stroke, and associated cardiovascular disease (CVD). The aim of this paper is to review the etiology of arterial stiffening and potential therapeutic approaches to modulate arterial fibrosis and stiffness. RECENT FINDINGS: The Framingham Heart Study demonstrated that arterial stiffness is an independent predictor of CVD and related morbidity and mortality...
July 6, 2018: Current Hypertension Reports
https://www.readbyqxmd.com/read/29980938/sympathetic-nervous-system-sleep-and-hypertension
#7
REVIEW
Gino Seravalle, Giuseppe Mancia, Guido Grassi
To evaluate the relation between sleep alterations, with or without breathing disorders, and incidence of hypertension and other cardiovascular diseases RECENT FINDINGS: Several studies have clearly shown the mechanisms linking sleep disorders and cardiovascular diseases. The sympathetic hyperactivity seems to play a fundamental role in favoring and sustaining the increase in blood pressure values. Several other mechanisms also contribute to this effect and to the increase cardiovascular risk. The mechanisms responsible for the increase in blood pressure values in subjects with alteration in sleep quantity and quality, with or without breathing disorders, have been clearly established...
July 6, 2018: Current Hypertension Reports
https://www.readbyqxmd.com/read/29980866/evaluation-and-management-of-stage-2-hypertension-in-pediatric-patients
#8
REVIEW
Yosuke Miyashita, Coral Hanevold
PURPOSE OF REVIEW: To update the definition and clinical practice of stage 2 hypertension (HTN) in pediatrics. RECENT FINDINGS: The 2017 American Academy of Pediatrics Clinical Practice Guideline (AAP CPG) for Screening and Management of High Blood Pressure in Children and Adolescent includes new normative blood pressure tables for children and adolescents ages 1 to 17 years and new definitions for stage 2 HTN. This review will highlight these aspects as well as new recommendations in the guideline specific to stage 2 HTN...
July 6, 2018: Current Hypertension Reports
https://www.readbyqxmd.com/read/29980865/future-direction-for-using-artificial-intelligence-to-predict-and-manage-hypertension
#9
REVIEW
Chayakrit Krittanawong, Andrew S Bomback, Usman Baber, Sripal Bangalore, Franz H Messerli, W H Wilson Tang
PURPOSE OF REVIEW: Evidence that artificial intelligence (AI) is useful for predicting risk factors for hypertension and its management is emerging. However, we are far from harnessing the innovative AI tools to predict these risk factors for hypertension and applying them to personalized management. This review summarizes recent advances in the computer science and medical field, illustrating the innovative AI approach for potential prediction of early stages of hypertension. Additionally, we review ongoing research and future implications of AI in hypertension management and clinical trials, with an eye towards personalized medicine...
July 6, 2018: Current Hypertension Reports
https://www.readbyqxmd.com/read/29974262/arterial-stiffness-in-hypertension-an-update
#10
REVIEW
Korshie Dumor, Michael Shoemaker-Moyle, Ravi Nistala, Adam Whaley-Connell
PURPOSE OF REVIEW: To update and review novel insights into the mechanisms, measurements, and therapeutic approaches to arterial stiffness. RECENT FINDINGS: Arterial (e.g., vascular) stiffness has been shown over time to prognosticate for cardiovascular and kidney outcomes. In this context, there has been increased interest behind the mechanisms that drive arterial stiffness beyond aging and interest in how to apply newer technologies in measurement of arterial stiffness...
July 4, 2018: Current Hypertension Reports
https://www.readbyqxmd.com/read/29971699/immigration-and-acculturation-impact-on-health-and-well-being-of-immigrants
#11
REVIEW
Talma Rosenthal
Among migrants who arrived in the USA and Europe, communicable diseases such as dermatologic, gastrointestinal, and respiratory infections are frequent; non-communicable diseases including chronic diseases such as hypertension and diabetes, and vaccine-preventable diseases are also prevalent. Refugees are often not up to date on routine immunizations and screenings for chronic diseases and cancer. In addition, many immigrants have trauma-related mental health problems, which are often not addressed by the healthcare systems where they reside...
July 3, 2018: Current Hypertension Reports
https://www.readbyqxmd.com/read/29971645/peripartum-cardiomyopathy-and-preeclampsia-overlapping-diseases-of-pregnancy
#12
REVIEW
Pavan Parikh, Lori Blauwet
PURPOSE OF REVIEW: Hypertensive disorders of pregnancy (HDP) often result in cardiac dysfunction and have been variably included as a risk factor for peripartum cardiomyopathy (PPCM). However, there is debate regarding the relationship between the two entities. RECENT FINDINGS: Diastolic dysfunction appears to be more predominant among gravidas with HDP, while systolic dysfunction predominates in PPCM. However, this finding is not consistent in all studies. Recent examinations of mortality and morbidity associated with PPCM in the setting of HDP do not demonstrate a predominant pattern with a mixture of results...
July 3, 2018: Current Hypertension Reports
https://www.readbyqxmd.com/read/29971632/preeclampsia-and-related-cardiovascular-risk-common-genetic-background
#13
REVIEW
Michalina Lisowska, Tadeusz Pietrucha, Agata Sakowicz
PURPOSE OF REVIEW: Preeclampsia (PE) is a hypertensive disorder exclusive for pregnancy. It affects women all over the world and poses a great threat to life, both for mother and child. No definitive treatment exists and placenta delivery comprises the only known cure for PE. One of the most severe complications observed in preeclamptic women is the occurrence of cardiovascular diseases (CVDs) later in life. RECENT FINDINGS: Both PE and CVDs share some of their pathogenic pathways and gene variations...
July 3, 2018: Current Hypertension Reports
https://www.readbyqxmd.com/read/29959593/management-of-vegf-targeted-therapy-induced-hypertension
#14
REVIEW
Stefano Caletti, Anna Paini, Maria Antonietta Coschignano, Carolina De Ciuceis, Matteo Nardin, Roberto Zulli, Maria Lorenza Muiesan, Massimo Salvetti, Damiano Rizzoni
PURPOSE OF REVIEW: From a physiological point of view, VEGFs (vascular endothelial growth factors) and their receptors (VEGFR) play a critical role in vascular development angiogenesis, endothelial function, and vascular tone. On the pathological side, VEGF-VEGFR signaling may induce dysregulated angiogenesis, which contributes to the growth and to the spread of tumors, being essential for neoplastic proliferation and invasion. RECENT FINDINGS: Pharmacological inhibition of VEGF-VEGFR is now a cornerstone in the treatment of many malignancies; however, treatment with VEGF inhibitors is commonly associated with an increase in blood pressure values...
June 29, 2018: Current Hypertension Reports
https://www.readbyqxmd.com/read/29909538/resistant-hypertension-time-to-consider-the-best-fifth-anti-hypertensive-treatment
#15
REVIEW
Andrea Pio-Abreu, Luciano F Drager
PURPOSE OF REVIEW: Resistant hypertension (RH) is a growing clinical condition worldwide associated with target-organ damage and poor prognosis compared to non-resistant counterparts. The purpose of this review is to perform a critical evaluation of preferable drug choices for managing RH highlighting the evidence that significant proportion of patients remained uncontrolled despite using four anti-hypertensive drugs. RECENT FINDINGS: Until recently, the fourth drug therapy was main derived from personal opinion or small interventional studies...
June 16, 2018: Current Hypertension Reports
https://www.readbyqxmd.com/read/29909475/stress-genes-and-hypertension-contribution-of-the-isiah-rat-strain-study
#16
REVIEW
Olga E Redina, Arcady L Markel
PURPOSE OF REVIEW: Acute psychoemotional stress is one of the causes of a sharp increase in blood pressure. However, the question if the stress may promote the hypertensive disease development is still open. This review aims, firstly, to show that the genetically determined enhanced responsiveness to stress is linked to sustained hypertension development and, secondly, to characterize the main physiological mechanisms and genetic factors implicated in the pathogenesis of stress-sensitive hypertension...
June 16, 2018: Current Hypertension Reports
https://www.readbyqxmd.com/read/29904903/nurse-s-contribution-to-alleviate-non-adherence-to-hypertension-treatment
#17
REVIEW
G Georgiopoulos, Z Kollia, V Katsi, D Oikonomou, C Tsioufis, D Tousoulis
PURPOSE OF REVIEW: Hypertension consists a major risk factor for cardiovascular events. Despite the proven effectiveness of antihypertensive treatment, approximately half of hypertensive patients have inadequate blood pressure control. Non-adherence to medication has been shown to be an important barrier to achieving adequate blood pressure control and nurse interventions can substantially improve therapeutic compliance. We sought to evaluate the role of nurse interventions in alleviating non-adherence to medication in patients with hypertension by performing a systematic review of the literature for all relevant articles...
June 15, 2018: Current Hypertension Reports
https://www.readbyqxmd.com/read/29892919/resistant-hypertension-in-pregnancy-how-to-manage
#18
REVIEW
Maria Rita Bortolotto, Rossana Pulcineli Vieira Francisco, Marcelo Zugaib
PURPOSE OF REVIEW: The concept of resistant hypertension may be changed during pregnancy by the physiological hemodynamic changes and the particularities of therapy choices in this period. This review discusses the management of pregnant patients with preexisting resistant hypertension and also of those who develop severe hypertension in gestation and puerperium. RECENT FINDINGS: The main cause of severe hypertension in pregnancy is preeclampsia, and differential diagnosis must be done with secondary or primary hypertension...
June 11, 2018: Current Hypertension Reports
https://www.readbyqxmd.com/read/29892833/treatment-of-hypertension-in-chronic-kidney-disease
#19
REVIEW
Rigas G Kalaitzidis, Moses S Elisaf
PURPOSE OF REVIEW: Chronic kidney disease (CKD) is recognized as a worldwide epidemic. Hypertension commonly coexists with CKD and its prevalence is progressively increasing as kidney function declines. RECENT FINDINGS: For patients with established CKD and/or diabetes with albuminuria, the updated hypertension guidelines have recommended a blood pressure (BP) goal < 130/80 mmHg. Blood pressure level above 130/80 mmHg in CKD patients requires lifestyle modifications and multiple antihypertensive medications...
June 11, 2018: Current Hypertension Reports
https://www.readbyqxmd.com/read/29884931/interplay-between-the-renin-angiotensin-system-the-canonical-wnt-%C3%AE-catenin-pathway-and-ppar%C3%AE-in-hypertension
#20
REVIEW
Alexandre Vallée, Bernard L Lévy, Jacques Blacher
PURPOSE OF REVIEW: Heterogeneous causes can determinate hypertension. RECENT FINDINGS: The renin-angiotensin system (RAS) has a major role in the pathophysiology of blood pressure. Angiotensin II and aldosterone are overexpressed during hypertension and lead to hypertension development and its cardiovascular complications. In several tissues, the overactivation of the canonical WNT/β-catenin pathway leads to inactivation of peroxisome proliferator-activated receptor gamma (PPARγ), while PPARγ stimulation induces a decrease of the canonical WNT/β-catenin pathway...
June 9, 2018: Current Hypertension Reports
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