journal
MENU ▼
Read by QxMD icon Read
search

Current Hypertension Reports

journal
https://www.readbyqxmd.com/read/28197835/selenium-vanadium-and-chromium-as-micronutrients-to-improve-metabolic-syndrome
#1
REVIEW
Sunil K Panchal, Stephen Wanyonyi, Lindsay Brown
Trace metals play an important role in the proper functioning of carbohydrate and lipid metabolism. Some of the trace metals are thus essential for maintaining homeostasis, while deficiency of these trace metals can cause disorders with metabolic and physiological imbalances. This article concentrates on three trace metals (selenium, vanadium, and chromium) that may play crucial roles in controlling blood glucose concentrations possibly through their insulin-mimetic effects. For these trace metals, the level of evidence available for their health effects as supplements is weak...
March 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28233242/ambiguities-in-the-guidelines-for-the-management-of-arterial-hypertension-indian-perspective-with-a-call-for-global-harmonization
#2
REVIEW
Harmeet Singh Rehan, Abhinav Grover, A P S Hungin
Many medical professional societies have formulated guidelines to treat hypertension, but there existed differences with respect to diagnosis, blood pressure (BP) targets, pharmacotherapy of hypertension, and grades of evidence. A MEDLINE search for hypertension guidelines was performed to compare Indian guidelines for hypertension (IGH) with these guidelines. A majority of the guidelines had consensus on the cutoff value (140/90 mmHg, recorded twice) to diagnose hypertension. The Joint National Committee 8 (JNC 8), IGH, Japanese Society of hypertension (JSH), Canadian Hypertension Education Program (CHEP), and American Society of Hypertension/International Society of Hypertension (ASH/ISH) guidelines provide a higher BP target for the elderly hypertensive populations, while the National Institute for Health and Care Excellence (NICE) and European Society of Hypertension (ESH) guidelines provided a lower BP target for the elderly patients...
February 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28233241/preeclampsia-a-cardiorenal-syndrome-in-pregnancy
#3
REVIEW
Andrew Smyth, Claudio Ronco, Vesna D Garovic
No abstract text is available yet for this article.
February 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28233240/effects-of-intrauterine-growth-restriction-and-female-sex-on-future-blood-pressure-and-cardiovascular-disease
#4
REVIEW
Gwendolyn K Davis, Ashley D Newsome, Norma B Ojeda, Barbara T Alexander
PURPOSE OF THE REVIEW: It is well-established that the age-related increase in blood pressure is augmented after menopause. Yet, the prevalence of hypertension is enhanced in low birth weight women relative to normal birth weight counterparts by 60 years of age suggesting that adverse influences during fetal life heighten cardiovascular risk in later life. RECENT FINDINGS: A changing hormonal milieu may contribute to increased cardiovascular risk that occurs after the menopausal transition...
February 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28233239/novel-cardiac-intracrine-mechanisms-based-on-ang-1-12-chymase-axis-require-a-revision-of-therapeutic-approaches-in-human-heart-disease
#5
REVIEW
Santiago Reyes, Jasmina Varagic, Sarfaraz Ahmad, Jessica VonCannon, Neal D Kon, Hao Wang, Leanne Groban, Che Ping Cheng, Louis J Dell'Italia, Carlos M Ferrario
PURPOSE OF THE REVIEW: Drugs targeting the renin-angiotensin system (RAS), namely angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers, are the most commonly prescribed drugs for patients with or at risk for cardiovascular events. However, new treatment strategies aimed at mitigating the rise of the heart failure pandemic are warranted because clinical trials show that RAS blockers have limited benefits in halting disease progression. The main goal of this review is to put forward the concept of an intracrine RAS signaling through the novel angiotensin-(1-12)/chymase axis as the main source of deleterious angiotensin II (Ang II) in cardiac maladaptive remodeling leading to heart failure (HF)...
February 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28233238/plasticity-of-renin-cells-in-the-kidney-vasculature
#6
REVIEW
R Ariel Gomez, Maria Luisa S Sequeira Lopez
During development, renin cells are precursors for arteriolar smooth muscle, mesangial cells, and interstitial pericytes. Those seemingly differentiated descendants retain the memory to re-express renin when there is a threat to homeostasis. Understanding how such molecular memory is constructed and regulated would be crucial to comprehend cell identity which is, in turn, intimately linked to homeostasis.
February 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28233237/current-perspectives-on-systemic-hypertension-in-heart-failure-with-preserved-ejection-fraction
#7
REVIEW
Marty C Tam, Ran Lee, Thomas M Cascino, Matthew C Konerman, Scott L Hummel
Heart failure with preserved ejection fraction (HFpEF) is a prevalent but incompletely understood syndrome. Traditional models of HFpEF pathophysiology revolve around systemic HTN and other causes of increased left ventricular afterload leading to left ventricular hypertrophy (LVH) and diastolic dysfunction. However, emerging models attribute the development of HFpEF to systemic proinflammatory changes secondary to common comorbidities which include HTN. Alterations in passive ventricular stiffness, ventricular-arterial coupling, peripheral microvascular function, systolic reserve, and chronotropic response occur...
February 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28233236/role-of-mitochondrial-dysfunction-in-hypertension-and-obesity
#8
REVIEW
Vicente Lahera, Natalia de Las Heras, Antonio López-Farré, Walter Manucha, León Ferder
Mitochondria are essential for the maintenance of normal physiological function of tissue cells. Mitochondria are subject to dynamic processes in order to establish a control system related to survival or cell death and adaptation to changes in the metabolic environment of cells. Mitochondrial dynamics includes fusion and fission processes, biogenesis, and mitophagy. Modifications of mitochondrial dynamics in organs involved in energy metabolism such as the pancreas, liver, skeletal muscle, and white adipose tissue could be of relevance for the development of insulin resistance, obesity, and type 2 diabetes...
February 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28185122/multidisciplinary-approach-in-the-treatment-of-resistant-hypertension
#9
REVIEW
S A Potthoff, O Vonend
With its high prevalence and the eminent number of undetected or poorly controlled patients, the management of arterial hypertension is still a challenging task. Uncontrolled blood pressure is the major adjustable risk factor for cardiovascular end organ damage for coronary heart disease, heart failure, stroke, and renal disease. Patients with resistant hypertension often need a multidisciplinary approach in order to control their blood pressure sustainably. In cooperation with hypertension specialists, the underlying cause for therapy resistance should be evaluated...
January 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28176250/hot-topic-global-burden-of-treating-hypertension-what-is-the-role-of-the-emergency-department
#10
REVIEW
Aaron M Brody, Vijaya A Kumar, Phillip D Levy
Hypertension (HTN) is the most common modifiable risk factor for cardiovascular disease (CVD) morbidity and mortality worldwide. Lower- and middle-income countries (LMICs) are projected to bear the vast majority of this disease burden, but local and regional health care delivery systems in these countries are ill equipped to meet this need. Emergency care is receiving increased recognition as a crucial component of public and community health. The rapid evolution of emergency care in LMICs provides a unique opportunity to develop innovative strategies, incorporating existing strengths of emergency departments, to address this paradigm shift in the disease burden associated with HTN on a global scale...
January 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28168678/lipidomics-in-the-study-of-hypertension-in-metabolic-syndrome
#11
REVIEW
Hemant Kulkarni, Manju Mamtani, John Blangero, Joanne E Curran
PURPOSE OF REVIEW: The entire gamut of changes in the lipid profile that precede, predict, and correlate with hypertension in metabolic syndrome is unknown. RECENT FINDINGS: The power, resolution, and accuracy of lipidomic assay technologies have brought us to the threshold of another information explosion. Understanding of hypertension and its pathophysiology especially within the setting of metabolic syndrome has been greatly improved by recent lipidomic studies...
January 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28155021/anti-angiogenesis-and-preeclampsia-in-2016
#12
REVIEW
Susanne Schrey-Petersen, Holger Stepan
PURPOSE OF REVIEW: Preeclampsia remains one of the most important complications in pregnancy worldwide. With this review, we aim to give an overview on important research findings over the last years and their effects on current clinical management. RECENT FINDINGS: The association between preeclampsia and altered angiogenesis is nowadays widely accepted. Only during the last years, assessment of angiogenic factors such as the soluble fms-like tyrosine kinase-1-to-placental growth factor (sFlt-1/PlGF) ratio has become available to everyday clinical practice with commercially available automated measurements...
January 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28150134/renal-artery-stenosis-in-patients-with-resistant-hypertension-stent-it-or-not
#13
REVIEW
Patricia Van der Niepen, Patrick Rossignol, Jean-Philippe Lengelé, Elena Berra, Pantelis Sarafidis, Alexandre Persu
After three large neutral trials in which renal artery revascularization failed to reduce cardiovascular and renal morbidity and mortality, renal artery stenting became a therapeutic taboo. However, this is probably unjustified as these trials have important limitations and excluded patients most likely to benefit from revascularization. In particular, patients with severe hypertension were often excluded and resistant hypertension was either poorly described or not conform to the current definition. Effective pharmacological combination treatment can control blood pressure in most patients with renovascular hypertension...
January 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28102522/present-and-future-of-interventional-treatment-of-resistant-hypertension
#14
REVIEW
Ayhan Yoruk, Sinan S Tankut, John P Gassler, John D Bisognano
The increasing prevalence of hypertension, a significant cause of disability and premature death throughout the world, is a major public health concern. This is especially true for the subset of patients who suffer from resistant hypertension, which is associated with a fourfold greater risk of cardiovascular events as compared to those hypertensive patients able to achieve target blood pressure. Though quite daunting in number and ill effect, hypertension remains the most common and the most important modifiable risk factor for coronary heart disease, congestive heart failure, peripheral vascular disease, stroke, and chronic kidney disease...
January 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28091868/the-un-observed-automated-office-blood-pressure-measurement-technique-used-in-the-sprint-study-points-to-a-standard-target-office-systolic-blood-pressure-140%C3%A2-mmhg
#15
REVIEW
Sverre E Kjeldsen, Giuseppe Mancia
The SPRINT study investigators used the un-observed automated office blood pressure measurement technique. When their achieved systolic blood pressure is corrected, target systolic blood pressure for most people remains unchanged: <140mmHg for prevention of cardiovascular diseases and death.
January 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28091867/arterial-aortic-stiffness-in-patients-with-resistant-hypertension-from-assessment-to-treatment
#16
REVIEW
James E Sharman, Pierre Boutouyrie, Stéphane Laurent
PURPOSE OF REVIEW: The purpose of the review is to examine whether measurement of aortic stiffness could be especially value-adding for risk stratification and treatment among patients with resistant hypertension (RH). RECENT FINDINGS: Adverse arterial remodeling and increased aortic stiffness is associated with RH, and it may be of additional clinical benefit to measure aortic stiffness in these patients. However, there is insufficient evidence to determine whether aortic stiffness is excessively high relative to the level of blood pressure (BP) among people with RH...
January 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28083801/unravelling-the-lesser-known-facets-of-angiotensin-ii-type-1-receptor
#17
REVIEW
Mayank Chaudhary, Shashi Chaudhary
PURPOSE OF REVIEW: Hypertension is an important risk factor in various pathologies. Despite enormous advancements in health sciences, the number of hypertensive individuals is increasing worldwide. The complex interplay between genetic and epigenetic factors seems to be a promising pathway to exploring the pathophysiology of hypertension. RECENT FINDINGS: Various single gene and genome wide association studies have generated huge but non-reproducible data that highlights the role of some additional but as yet unidentified factor(s) in disease outcome...
January 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/27889904/how-to-screen-for-non-adherence-to-antihypertensive-therapy
#18
REVIEW
Pankaj Gupta, Prashanth Patel, Robert Horne, Heather Buchanan, Bryan Williams, Maciej Tomaszewski
The quality of assessment of non-adherence to treatment in hypertensive is poor. Within this review, we discuss the different methods used to assess adherence to blood-pressure-lowering medications in hypertension patients. Subjective reports such as physicians' perceptions are inaccurate, and questionnaires completed by patients tend to overreport adherence and show a low diagnostic specificity. Indirect objective methods such as pharmacy database records can be useful, but they are limited by the robustness of the recorded data...
December 2016: Current Hypertension Reports
https://www.readbyqxmd.com/read/27878563/asymptomatic-elevated-bp-and-the-hypertensive-insurgency
#19
REVIEW
Candace D McNaughton, Phillip Levy
No abstract text is available yet for this article.
December 2016: Current Hypertension Reports
https://www.readbyqxmd.com/read/27837398/role-of-microrna-in-endothelial-dysfunction-and-hypertension
#20
REVIEW
Miruna Nemecz, Nicoleta Alexandru, Gabriela Tanko, Adriana Georgescu
PURPOSE OF REVIEW: Hypertension is either a cause or a consequence of the endothelial dysfunction and a major risk factor for cardiovascular disease (CVD). In vitro and in vivo studies established that microRNAs (miRNAs) are decisive for endothelial cell gene expression and function in various pathological conditions associated with CVD. This review provides an overview of the miRNA role in controlling the key connections between endothelial dysfunction and hypertension. RECENT FINDINGS: Herein we summarize the present understanding of mechanisms underlying hypertension and its associated endothelial dysfunction as well as the miRNA role in endothelial cells with accent on the modulation of renin-angiotensin-aldosterone-system, nitric oxide, oxidative stress and on the control of vascular inflammation and angiogenesis in relation to endothelial dysfunction in hypertension...
December 2016: Current Hypertension Reports
journal
journal
34706
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"