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Current Cardiology Reports

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https://www.readbyqxmd.com/read/28785990/telestroke
#1
REVIEW
Oana M Dumitrascu, Bart M Demaerschalk
PURPOSE OF REVIEW: This study aims to describe the current state of telestroke clinical applications and policies, in addition to key technical and operational aspects of the telemedicine practice. RECENT FINDINGS: Delivery of telestroke services for neurovascular care expanded from the intravenous alteplase decision and administration in acute emergency department settings to a continuum of services in mobile and inpatient stroke units, intensive care units, virtual stroke clinics, rehabilitation, and clinical research...
September 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28779286/where-does-inflammation-fit
#2
REVIEW
Luigi M Biasucci, Giulio La Rosa, Daniela Pedicino, Alessia D'Aiello, Mattia Galli, Giovanna Liuzzo
PURPOSE OF REVIEW: This review focuses on the complex relationship between inflammation and the onset of acute coronary syndrome and heart failure. RECENT FINDINGS: In the last few years, two important lines of research brought new and essential information to light in the pathogenesis of acute coronary syndrome: a) the understanding of the immune mediate mechanisms of inflammation in Ischemic Heart Disease (IHD) and b) evidence that the inflammatory mechanisms associated with atherosclerosis and its complications can be modulated by anti-inflammatory molecules...
September 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28779285/radiofrequency-ablation-in-arrhythmogenic-right-ventricular-cardiomyopathy-arvc
#3
REVIEW
Jorge Romero, Michael Grushko, David F Briceño, Andrea Natale, Luigi Di Biase
PURPOSE OF REVIEW: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a heritable form of cardiomyopathy, typically with autosomal dominant transmission, shown to be a defect in the cardiac desmosomes, with distinct regional and histopathological features. Clinically, this can ultimately result in bi-ventricular failure and/or malignant ventricular tachycardia (VT) via reentrant circuits created by patchy scar formation. We sought to review the current treatment for ventricular arrhythmias in the setting of ARVC, with particular attention to radiofrequency (RF) ablation and its varied techniques, along with potential therapies in the ablation spectrum...
September 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28779284/cholesterol-management-in-the-era-of-pcsk9-inhibitors
#4
REVIEW
Anna Svatikova, Stephen L Kopecky
PURPOSE OF REVIEW: Cholesterol management in the current era is discussed. Aggressive reduction of low density lipoprotein (LDL) cholesterol plays a key role in primary and secondary prevention of heart disease. Statins are the recommended first-line therapy in patients with hyperlipidemia; however, additional complementary approaches are frequently needed for patients who fail to reach their target LDL. RECENT FINDINGS: Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors are novel drugs that provide dramatic lowering of LDL and promise outcome benefit...
September 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28752280/complementary-role-of-echocardiography-and-cardiac-magnetic-resonance-in-hypertrophic-cardiomyopathy
#5
REVIEW
Waseem Hindieh, Raymond Chan, Harry Rakowski
PURPOSE OF REVIEW: This review discusses the complementary roles of echocardiography and cardiac magnetic resonance in the diagnosis and management of patients with hypertrophic cardiomyopathy (HCM). RECENT FINDINGS: Imaging using novel echocardiographic techniques and cardiac magnetic resonance (CMR) imaging in HCM has demonstrated incremental utility in diagnosis and management guidance. Application of 3-D imaging has improved assessment of left ventricular (LV) mass and volume by echocardiography...
September 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28752279/ablative-radiotherapy-as-a-noninvasive-alternative-to-catheter-ablation-for-cardiac-arrhythmias
#6
REVIEW
Paul C Zei, Scott Soltys
PURPOSE OF REVIEW: Stereotactic radioablation is a commonly utilized technology to noninvasively treat solid tumors with precision and efficacy. Using a robotic arm mounted delivery system, multiple low-dose ionizing radiation beams are delivered from multiple angles, concentrating ablative energy at the target tissue. Recently, this technology has been evaluated for treatment of cardiac arrhythmias. This review will present the basic underlying principles, proof-of-principle studies, and clinical experience with stereotactic arrhythmia radioablation...
September 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28752278/predictors-and-therapy-of-cardiomyopathy-caused-by-frequent-ventricular-ectopy
#7
REVIEW
Ghaith Sharaf Dabbagh, Frank Bogun
PURPOSE OF REVIEW: The aim of this review is to describe predictors and therapeutic principles for PVC-induced cardiomyopathy. RECENT FINDINGS: PVC-induced cardiomyopathy is a treatable condition resulting in a reversible form of cardiomyopathy. PVC-induced cardiomyopathy has only recently been recognized as an entity that causes a reversible form of cardiomyopathy. The mechanism of development of PVC-induced cardiomyopathy has not yet been elucidated, although dyssynchrony appears to play a major role...
September 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28752277/myocardial-tissue-engineering-for-regenerative-applications
#8
REVIEW
Buntaro Fujita, Wolfram-Hubertus Zimmermann
PURPOSE OF REVIEW: This review provides an overview of the current state of tissue-engineered heart repair with a special focus on the anticipated modes of action of tissue-engineered therapy candidates and particular implications as to transplant immunology. RECENT FINDINGS: Myocardial tissue engineering technologies have made tremendous advances in recent years. Numerous different strategies are under investigation and have reached different stages on their way to clinical translation...
September 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28752276/nutrition-education-for-cardiologists-the-time-has-come
#9
REVIEW
Stephen Devries, Andrew M Freeman
PURPOSE OF REVIEW: Nutrition is a cornerstone of cardiovascular health, yet the training of cardiovascular specialists in nutrition has been called into question. This report summarizes the current state of nutrition education in the training of cardiovascular specialists and offers recommendations for curricular enhancements. RECENT FINDINGS: Medical students receive an average of fewer than 20 h of nutrition education, largely confined to basic sciences and discussion of vitamin deficiency states...
September 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28752275/the-impact-of-antihypertensive-medications-on-bone-mineral-density-and-fracture-risk
#10
REVIEW
Joshua I Barzilay, Barry R Davis, Sara L Pressel, Alokananda Ghosh, Rachel Puttnam, Karen L Margolis, Paul K Whelton
PURPOSE OF REVIEW: This review summarizes the impact of thiazide diuretics on fracture risk in older hypertensive individuals. RECENT FINDINGS: We performed a post hoc evaluation of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial, a randomized, prospective, double blind hypertension study comparing a thiazide-like diuretic, a calcium channel blocker (CCB), and an angiotensin converting enzyme inhibitor (ACEi). We examined the risk of hip and pelvic fractures during the in-trial period (n = 22,180 participants; mean 4...
September 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28752274/renal-artery-stenosis-new-findings-from-the-coral-trial
#11
REVIEW
Rajesh Gupta, Salem Assiri, Christopher J Cooper
PURPOSE OF REVIEW: The goal of this review is to summarize recent advances in the field and highlight important new insights from the Cardiovascular Outcomes in Renal Atherosclerotic Lesions (CORAL) trial regarding the optimal management of patients with renal artery stenosis (RAS). RECENT FINDINGS: The CORAL trial demonstrated that subjects with RAS had similar outcomes whether randomized to optimal medical therapy alone or optimal medical therapy plus renal artery stenting...
September 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28801790/cardiovascular-disease-the-nitric-oxide-pathway-and-risk-of-cognitive-impairment-and-dementia
#12
REVIEW
Blossom C M Stephan, Stephanie L Harrison, Hannah A D Keage, Abrar Babateen, Louise Robinson, Mario Siervo
PURPOSE OF REVIEW: In this review, we summarise the evidence on the association between cardiovascular disease (CVD) and cognitive impairment and explore the role of the nitric oxide (NO) pathway as a causal mechanism. RECENT FINDINGS: Evidence from epidemiological studies suggests that the presence of CVD and its risk factors in midlife is associated with an increased risk of later life cognitive impairment and dementia. It is unclear what is driving this association but risk may be conveyed via an increase in neurodegeneration (e...
August 11, 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28795289/beyond-pulmonary-vein-isolation-the-role-of-additional-sites-in-catheter-ablation-of-atrial-fibrillation
#13
REVIEW
Li-Wei Lo, Yenn-Jiang Lin, Shih-Lin Chang, Yu-Feng Hu, Fa-Po Chung, Shih-Ann Chen
PURPOSE OF REVIEW: Pulmonary vein (PV) isolation is the cornerstone of atrial fibrillation (AF) ablation. However, the long-term procedural outcome remains suboptimal and there is a frequent need for repeat ablation procedure, especially in patients with non-paroxysmal AF. The review article summarizes the rationales, recent evidences, and strategies of ablation of extra-PV sites and its clinical outcomes. RECENT FINDINGS: It is a consensus that durable PV isolations are a definite therapy in patients with paroxysmal AF...
August 9, 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28744764/the-miracle-baby-grows-up-hypoplastic-left-heart-syndrome-in-the-adult
#14
REVIEW
Matthew Lewis, Marlon Rosenbaum
PURPOSE OF REVIEW: Hypoplastic left heart syndrome (HLHS) is characterized by underdevelopment of the mitral valve, left ventricle, and aorta and is ultimately palliated with a single-ventricle repair. Universally fatal in infancy prior to the advent of modern surgical techniques, the majority of HLHS patients will now reach adulthood. However, despite improvements in early survival, the HLHS population continues to face significant morbidity and early mortality. This review delineates common sources of patient morbidity and highlights areas in need of additional research for this growing segment of the adult congenital heart disease population...
August 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28688022/mitral-valve-disease-a-comprehensive-review
#15
REVIEW
Serge C Harb, Brian P Griffin
PURPOSE OF REVIEW: This review aims to provide a comprehensive assessment of mitral valve disease, both mitral stenosis and mitral regurgitation, starting with an overview of the valve anatomy. RECENT FINDINGS: The advent of three-dimensional imaging has allowed a better representation of the valve anatomy. Rheumatic disease is still the number one cause of mitral stenosis worldwide and percutaneous balloon mitral valvuloplasty remains the therapy of choice when indicated and in anatomically eligible patients...
August 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28667405/utilizing-hybrid-techniques-to-maximize-clinical-outcomes-in-congenital-heart-disease
#16
REVIEW
David W Bearl, Gregory A Fleming
PURPOSE OF REVIEW: The past couple of decades have brought tremendous advances to the field of pediatric and adult congenital cardiology. Recent collaborations between interventional cardiologists and cardiac surgeons have sparked novel innovative hybrid procedures that provide potentially safer, faster, and less invasive alternatives to the management of many diseases. This paper will review the most recent advances in hybrid interventions in the field of pediatric and adult congenital cardiology...
August 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28660552/adverse-remodeling-and-reverse-remodeling-after-myocardial-infarction
#17
REVIEW
Ankeet S Bhatt, Andrew P Ambrosy, Eric J Velazquez
PURPOSE OF REVIEW: The purpose of this review it to summarize the current literature on remodeling after myocardial infarction, inclusive of pathophysiological considerations, imaging modalities, treatment strategies, and future directions. RECENT FINDINGS: As patients continue to live longer after myocardial infarction (MI), the prevalence of post-MI heart failure continues to rise. Changes in the left ventricle (LV) after MI involve complex interactions between cellular and extracellular components, under neurohormonal regulation...
August 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28656481/heart-failure-with-preserved-ejection-fraction-and-future-pharmacological-strategies-a-glance-in-the-crystal-ball
#18
REVIEW
Carsten Tschöpe, Sophie Van Linthout, Behrouz Kherad
PURPOSE OF REVIEW: The current definition of heart failure is mainly based on an inappropriate measure of cardiac function, i.e., left ventricular ejection fraction (LVEF). The initial sole entity, heart failure with reduced ejection fraction (HFrEF, LVEF <40%), was complemented by the addition of heart failure with preserved ejection fraction (HFpEF, LVEF ≥50%) and most recently, heart failure with mid-range ejection fraction (HFmrEF, LVEF 40-49%). Initially, HFpEF was believed to be a purely left ventricular diastolic dysfunction...
August 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28653131/novel-risk-stratification-assays-for-acute-coronary-syndrome
#19
REVIEW
Haitham M Ahmed, Stanley L Hazen
PURPOSE OF REVIEW: Since identification of aspartate aminotransferase as the first cardiac biomarker in the 1950s, there have been a number of new markers used for myocardial damage detection over the decades. There have also been several generations of troponin assays, each with progressively increasing sensitivity for troponin detection. Accordingly, the "standard of care" for myocardial damage detection continues to change. The purpose of this paper is to review the clinical utility, biological mechanisms, and predictive value of these various biomarkers in contemporary clinical studies...
August 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28646446/innovations-in-the-endovascular-management-of-critical-limb-ischemia-retrograde-tibiopedal-access-and-advanced-percutaneous-techniques
#20
REVIEW
Jihad A Mustapha, Larry J Diaz-Sandoval, Fadi Saab
PURPOSE OF REVIEW: Retrograde tibiopedal access and interventions have contributed to advance of endovascular techniques to treat critical limb ischemia (CLI) patients. This review encompasses the spectrum from advanced diagnostic imaging and technical therapeutic approaches for infrapopliteal occlusions, to a discussion of current standards and future directions. RECENT FINDINGS: Contemporary studies of infrapopliteal angioplasty show suboptimal short-term and 1-year clinical outcomes...
August 2017: Current Cardiology Reports
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