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European Journal of Nutrition

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https://www.readbyqxmd.com/read/28735358/il-10-and-tgf-%C3%AE-unbalanced-levels-in-neutrophils-contribute-to-increase-inflammatory-cytokine-expression-in-childhood-obesity
#1
Nayara I Medeiros, Rafael T Mattos, Carlos A Menezes, Rafaelle C G Fares, André Talvani, Walderez O Dutra, Fabrício Rios-Santos, Rodrigo Correa-Oliveira, Juliana A S Gomes
PURPOSE: Obesity is a multifactorial disease, associated with metabolic disorders, chronic low-grade inflammation, and impaired immunity. This study aimed to evaluate the childhood obesity-associated effects on neutrophil activation and cytokine production. METHODS: We evaluated activation and recognition markers and cytokine production in neutrophils from the peripheral blood of children with obesity and normal weight using multicolor flow cytometry. RESULTS: We demonstrate a higher frequency of neutrophils in childhood obesity group (CO) compared to normal-weight group (NW)...
July 22, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28733927/nut-intake-and-5-year-changes-in-body-weight-and-obesity-risk-in-adults-results-from-the-epic-panacea-study
#2
Heinz Freisling, Hwayoung Noh, Nadia Slimani, Véronique Chajès, Anne M May, Petra H Peeters, Elisabete Weiderpass, Amanda J Cross, Guri Skeie, Mazda Jenab, Francesca R Mancini, Marie-Christine Boutron-Ruault, Guy Fagherazzi, Verena A Katzke, Tilman Kühn, Annika Steffen, Heiner Boeing, Anne Tjønneland, Cecilie Kyrø, Camilla P Hansen, Kim Overvad, Eric J Duell, Daniel Redondo-Sánchez, Pilar Amiano, Carmen Navarro, Aurelio Barricarte, Aurora Perez-Cornago, Konstantinos K Tsilidis, Dagfinn Aune, Heather Ward, Antonia Trichopoulou, Androniki Naska, Philippos Orfanos, Giovanna Masala, Claudia Agnoli, Franco Berrino, Rosario Tumino, Carlotta Sacerdote, Amalia Mattiello, H Bas Bueno-de-Mesquita, Ulrika Ericson, Emily Sonestedt, Anna Winkvist, Tonje Braaten, Isabelle Romieu, Joan Sabaté
PURPOSE: There is inconsistent evidence regarding the relationship between higher intake of nuts, being an energy-dense food, and weight gain. We investigated the relationship between nut intake and changes in weight over 5 years. METHODS: This study includes 373,293 men and women, 25-70 years old, recruited between 1992 and 2000 from 10 European countries in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Habitual intake of nuts including peanuts, together defined as nut intake, was estimated from country-specific validated dietary questionnaires...
July 21, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28730375/higher-dietary-glycemic-index-but-not-glycemic-load-is-associated-with-a-lower-prevalence-of-depressive-symptoms-in-a-cross-sectional-study-of-young-and-middle-aged-japanese-women
#3
Naoko Minobe, Kentaro Murakami, Satomi Kobayashi, Hitomi Suga, Satoshi Sasaki
OBJECTIVE: Epidemiologic evidence on the associations between dietary glycemic index (GI) and glycemic load (GL) and depressive symptoms is not only limited, particularly in Asian populations where dietary GI and GL are typically higher than in Western countries, but also inconclusive. This cross-sectional study examined these associations in Japanese women. METHODS: Subjects were 3963 young (age 18-years) and 3826 middle-aged (mean age 47.8 years) Japanese women...
July 20, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28725942/l-arginine-supplementation-prevents-allodynia-and-hyperalgesia-in-painful-diabetic-neuropathic-rats-by-normalizing-plasma-nitric-oxide-concentration-and-increasing-plasma-agmatine-concentration
#4
Lusliany J Rondón, M C Farges, N Davin, B Sion, A M Privat, M P Vasson, A Eschalier, C Courteix
PURPOSE: Neuropathic pain is a common diabetic complication. It is characterized by symptoms of spontaneous and stimulus-evoked pain including hyperalgesia and allodynia. L-Arginine is a common precursor of many metabolites of biological interest, in particular, nitric oxide (NO), ornithine, and hence polyamines. In central nervous system, NO, glutamate, and polyamines share an N-methyl-D-aspartate (NMDA) receptor-mediated effect. We hypothesized that a variation in arginine metabolism caused by diabetes may contribute to development and maintenance of neuropathic pain and to the worsening of clinical and biological signs of diabetes...
July 19, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28721562/reduced-energy-availability-implications-for-bone-health-in-physically-active-populations
#5
REVIEW
Maria Papageorgiou, Eimear Dolan, Kirsty J Elliott-Sale, Craig Sale
PURPOSE: The present review critically evaluates existing literature on the effects of short- and long-term low energy availability (EA) on bone metabolism and health in physically active individuals. METHODS: We reviewed the literature on the short-term effects of low EA on markers of bone metabolism and the long-term effects of low EA on outcomes relating to bone health (bone mass, microarchitecture and strength, bone metabolic markers and stress fracture injury risk) in physically active individuals...
July 18, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28718016/blackcurrant-anthocyanins-stimulated-cholesterol-transport-via-post-transcriptional-induction-of-ldl-receptor-in-caco-2-cells
#6
Bohkyung Kim, Minkyung Bae, Young-Ki Park, Hang Ma, Tao Yuan, Navindra P Seeram, Ji-Young Lee
PURPOSES: We previously showed that polyphenol-rich blackcurrant extract (BCE) showed a hypocholesterolemic effect in mice fed a high fat diet. As direct cholesterol removal from the body via the intestine has been recently appreciated, we investigated the effect of BCE on the modulation of genes involved in intestinal cholesterol transport using Caco-2 cells as an in vitro model. METHODS: Caco-2 cells were treated with BCE to determine its effects on mRNA and protein expression of genes important for intestinal cholesterol transport, low-density lipoprotein (LDL) uptake, cellular cholesterol content, and cholesterol transport from basolateral to apical membrane of Caco-2 cell monolayers...
July 17, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28718015/capable-and-credible-challenging-nutrition-science
#7
EDITORIAL
Bart Penders, Anna Wolters, Edith F Feskens, Fred Brouns, Machteld Huber, Els L M Maeckelberghe, Gerjan Navis, Theo Ockhuizen, Jogchum Plat, Jan Sikkema, Marianne Stasse-Wolthuis, Pieter van 't Veer, Marcel Verweij, Jan de Vries
Nutrition science has enriched our understanding of how to stay healthy by producing valuable knowledge about the interaction of nutrients, food, and the human body. Nutrition science also has raised societal awareness about the links between food consumption and well-being, and provided the basis for food regulations and dietary guidelines. Its collaborative and interdisciplinary research has accomplished much, scientifically and socially. Despite this, nutrition science appears to be in crisis and is currently confronted with a public reluctance to trust nutritional insights...
July 17, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28718014/protein-hydrolysate-from-canned-sardine-and-brewing-by-products-improves-tnf-%C3%AE-induced-inflammation-in-an-intestinal-endothelial-co-culture-cell-model
#8
Elsa F Vieira, John Van Camp, Isabel M P L V O Ferreira, Charlotte Grootaert
PURPOSE: The anti-inflammatory activity of sardine protein hydrolysates (SPH) obtained by hydrolysis with proteases from brewing yeast surplus was ascertained. METHODS: For this purpose, a digested and desalted SPH fraction with molecular weight lower than 10 kDa was investigated using an endothelial cell line (EA.hy926) as such and in a co-culture model with an intestinal cell line (Caco-2). Effects of SPH <10 kDa on nitric oxide (NO) production, reactive oxygen species (ROS) inhibition and secretion of monocyte chemoattractant protein 1 (MCP-1), vascular endothelial growth factor (VEGF), chemokine IL-8 (IL-8) and intercellular adhesion molecule-1 (ICAM-1) were evaluated in TNF-α-treated and untreated cells...
July 17, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28712053/soy-isoflavone-consumption-and-age-at-pubarche-in-adolescent-males
#9
Gina Segovia-Siapco, Peter Pribis, Keiji Oda, Joan Sabaté
PURPOSE: Isoflavones have estrogenic properties that may adversely affect pubertal development of boys. We examined if soy isoflavone consumption is associated with age at pubarche (first onset of pubic hair) in a male population with a wide range of soy intake. METHODS: Boys aged 12-18 years (n = 248) who attended schools around Adventist universities in Southern California and Michigan self-reported their age at pubarche. Intake of soy isoflavones was assessed using a validated Web-based food frequency questionnaire; consumption levels were designated as low, moderate, and high...
July 15, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28707217/baseline-glucoregulatory-function-moderates-the-effect-of-dairy-milk-and-fruit-juice-on-postprandial-cognition-in-healthy-young-adults
#10
Jason R Anderson, Misty A W Hawkins, John Updegraff, John Gunstad, Mary Beth Spitznagel
PURPOSE: Few studies have examined acute cognitive effects of dairy products. Prior work suggests baseline glucoregulatory function may moderate the relationship between macronutrient profile and postprandial cognition. This study examined the role of glucoregulatory function in postprandial cognition after milk, fruit juice, and a water control. We hypothesized juice would improve cognition in those with lower fasting glucose, while milk would improve cognition in those with higher fasting glucose...
July 13, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28702720/soft-drinks-consumption-is-associated-with-nonalcoholic-fatty-liver-disease-independent-of-metabolic-syndrome-in-chinese-population
#11
Ge Meng, Bo Zhang, Fei Yu, Chunlei Li, Qing Zhang, Li Liu, Hongmei Wu, Yang Xia, Xue Bao, Hongbin Shi, Qian Su, Yeqing Gu, Liyun Fang, Huijun Yang, Bin Yu, Shaomei Sun, Xing Wang, Ming Zhou, Qiyu Jia, Huanli Jiao, Bangmao Wang, Qi Guo, Livia A Carvalhoa, Zhong Sun, Kun Song, Ming Yu, Kaijun Niu
PURPOSE: Excessive consumption of soft drinks is associated with nonalcoholic fatty liver disease (NAFLD). However, the association between soft drinks consumption and NAFLD is unclear in non-Caucasian adults with relatively low soft drinks consumption. The aim of this study was to assess the association between soft drinks consumption and NAFLD in Chinese adults. METHODS: A cross-sectional study was conducted with 26,790 adults living in Tianjin, China. NAFLD (with elevated alanine aminotransferase [ALT]) was diagnosed by the liver ultrasonography and serum ALT concentrations...
July 12, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28702719/dietary-iron-intake-and-availability-are-related-to-maternal-education-level-in-overweight-obese-adolescents
#12
Chaleelak Thongprasert, Carol Hutchinson, Warapone Satheannoppakao, Mathuros Tipayamongkholgul
PURPOSE: To compare intakes of dietary iron and enhancers and inhibitors of iron absorption between overweight/obese (OW/OB) adolescents and their normal weight (NW) peers, and between parental education levels stratified by weight status. METHODS: This was a comparative cross-sectional study of adolescents (n 121 OW/OB and n 102 NW) aged 12-14 years, attending a secondary school in Nonthaburi province, Thailand. Socio-demographic data were obtained from participants' parents using a questionnaire...
July 12, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28699087/effects-of-endurance-training-on-autophagy-and-apoptotic-signaling-in-visceral-adipose-tissue-of-prolonged-high-fat-diet-fed-rats
#13
Sílvia Rocha-Rodrigues, Inês O Gonçalves, Jorge Beleza, António Ascensão, José Magalhães
PURPOSE: Autophagy and apoptosis play critical roles in both development and tissue homeostasis in response to (patho)physiological stimuli, such as high-fat diet (HFD) and endurance training (ET). Therefore, we aimed to investigate how ET modulates autophagy and apoptotic-related signaling in visceral adipose tissue of long-standing HFD-fed rats. METHODS: The study was conducted over a 17-week period on Sprague-Dawley rats, which were divided into four groups (n = 8/group): standard diet sedentary (STD+SED), high-fat diet sedentary (HFD+SED), standard diet ET (STD+ET) and high-fat diet ET (HFD+ET)...
July 11, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28695325/a-modified-response-of-nafld-patients-with-non-significant-fibrosis-in-nutritional-counseling-according-to-gckr-rs1260326
#14
Andriana C Kaliora, Ioanna Panagiota Kalafati, Aristea Gioxari, Anastasia Diolintzi, Alexandros Kokkinos, George V Dedoussis
AIM: To investigate the association between GCKR gene and nutritional treatment in NAFLD-related biomarkers. METHODS: This was an open-label and single-arm clinical trial in 44 overweight or obese adults with NAFLD receiving nutritional counseling for 6 months. Nutritional data, MedDietScore, clinical, biochemical, inflammatory and oxidative stress biomarkers were evaluated before and after intervention. Further, we genotyped GCKR rs1260326 and in T-allele carriers and non-Τ-carriers we assessed associations between the GCKR variant and nutritional counseling related to change in all biomarkers evaluated...
July 10, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28695324/the-effect-of-almonds-on-vitamin-e-status-and-cardiovascular-risk-factors-in-korean-adults-a-randomized-clinical-trial
#15
Hana Jung, C-Y Oliver Chen, Jeffrey B Blumberg, Ho-Kyung Kwak
PURPOSE: Almonds have shown to beneficially modify some cardiovascular risk factors in clinical trials conducted in diverse ethnic populations but this relationship has never been tested in Koreans. Thus, we tested the impact of almonds consumed as a snack within the context of a typical Korean diet on cardiovascular risk factors. METHODS: We conducted a randomized, crossover trial in a free-living setting with a 2-week run-in period, two 4-week intervention phases, and a 2-week washout period between interventions...
July 10, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28687934/co-administration-of-a-konjac-based-fibre-blend-and-american-ginseng-panax-quinquefolius-l-on-glycaemic-control-and-serum-lipids-in-type-2-diabetes-a-randomized-controlled-cross-over-clinical-trial
#16
Alexandra L Jenkins, Linda M Morgan, Jacqueline Bishop, Elena Jovanovski, David J A Jenkins, Vladimir Vuksan
PURPOSE: Use of polypharmacy in the treatment of diabetes is the norm; nonetheless, optimal control is often not achieved. Konjac-glucomannan-based fibre blend (KGB) and American ginseng (AG) have individually been shown to improve glycaemia and CVD risk factors in type 2 diabetes. The aim of this study was to determine whether co-administration of KGB and AG could improve diabetes control beyond conventional treatment. METHOD: Thirty-nine participants with type 2 diabetes (6...
July 7, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28687933/cellular-zinc-homeostasis-modulates-polarization-of-thp-1-derived-macrophages
#17
Laura Dierichs, Veronika Kloubert, Lothar Rink
PURPOSE: Polarization of macrophages by environmental stimuli leads to the characteristic of different phenotypes that exhibit distinct functions, ranging in a continuous spectrum from pro-inflammatory M1 up to immunoregulatory and wound-healing M2 macrophages. Diseases like cancer, allergic asthma or diabetes are associated with an M1/M2 imbalance. Owing to the importance of the essential trace element zinc for the immune system and its involvement in signal transduction as a second messenger, we investigated the impact of zinc on M1 and M2 polarization of macrophages in vitro...
July 7, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28676973/chronic-consumption-of-fructose-in-combination-with-trans-fatty-acids-but-not-with-saturated-fatty-acids-induces-nonalcoholic-steatohepatitis-with-fibrosis-in-rats
#18
Sugeedha Jeyapal, Uday Kumar Putcha, Venkata Surekha Mullapudi, Sudip Ghosh, Anil Sakamuri, Suryam Reddy Kona, Sai Santosh Vadakattu, Chandana Madakasira, Ahamed Ibrahim
PURPOSE: Consumption of Western diet high in fat and fructose has been attributed to the recent epidemic of nonalcoholic fatty liver disease (NAFLD). However, the impact of specific fatty acids on the progression of NAFLD to nonalcoholic steatohepatitis (NASH) is poorly understood. In the present study, we investigated the chronic effects of consumption of fructose in combination with saturated fatty acids (SFA) or trans fatty acids (TFA) on the development of NAFLD. METHODS: Male Sprague-Dawley rats were randomly assigned to six isocaloric starch/high fructose (44% of calories), high fat (39% calories) diet containing either starch-peanut oil, fructose-peanut oil, fructose-palmolein, fructose-clarified butter, fructose-coconut oil or fructose-partially hydrogenated vegetable oil and fed for 24 weeks...
July 4, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28667457/the-dietary-form-of-choline-during-lactation-affects-maternal-immune-function-in-rats
#19
N S Dellschaft, C Richard, E D Lewis, S Goruk, R L Jacobs, J M Curtis, C J Field
PURPOSE: The present study was designed to determine the effects of both choline form and availability on maternal immune function during lactation. METHODS: Sprague-Dawley rats were randomized to one of the three diets 24-48 h before parturition and fed ad libitum until 21 days postnatal: 1 g/kg choline as free choline (C, n = 11), the current form, and amount of choline in commercial diets; 1 g/kg choline as phosphatidylcholine (PC1, n = 11); or 2.5 g/kg choline as PC (PC2...
June 30, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28656391/antioxidant-activity-of-whole-grain-highland-hull-less-barley-and-its-effect-on-liver-protein-expression-profiles-in-rats-fed-with-high-fat-diets
#20
Xuejuan Xia, Guannan Li, Yuxiao Xing, Yongbo Ding, Tingyuan Ren, Jianquan Kan
PURPOSE: Whole grain exhibits potential for regulating lipid levels, possibly because of its antioxidant activity. This study aims to investigate the antioxidant activity of whole grain highland hull-less barley (WHLB) and its effect on liver protein expression profiles in rats fed with high-fat diets. METHODS: Antioxidant activity of WHLB was investigated in vitro by analyzing phenolic and pentosan contents and oxygen radical absorbance capacity (ORAC). Proteins involved in lipid regulation were investigated in vivo by analyzing liver protein expression profiles in Sprague-Dawley rats fed with high-fat diet (HFD) with or without WHLB...
June 27, 2017: European Journal of Nutrition
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