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Cerebrum: the Dana Forum on Brain Science

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https://www.readbyqxmd.com/read/27408679/a-new-approach-for-epilepsy
#1
Ray Dingledine, Bjørnar Hassel
About one-third of the 65 million people worldwide affected by epilepsy are treatment-resistant, and the degree to which they suffer from seizures and convulsions can vary widely. Problems occur when nerve cells in the brain fail to communicate properly. A new study has found that inhibiting an enzyme that is critical in metabolic communication has an anti-seizure effect in epileptic mice. These findings, the authors believe, may very well initiate a shift to new therapeutic approaches.
May 2016: Cerebrum: the Dana Forum on Brain Science
https://www.readbyqxmd.com/read/27408678/the-neuro-funding-rollercoaster
#2
Harry M Tracy
Compared to the money dedicated to cancer and cardiology, funding for neuroscience research has lagged behind for decades. But things are starting to change. From the White House's Brain Initiative to the Ice Bucket Challenge for ALS to some recent sizeable gifts to universities, money for brain research appears to be on the rise. But, as our author explains, research and development funding from private and corporate lenders for cognitive neuroscience-an area that he has spent years tracking-is also vital to the quality of life for millions of people...
May 2016: Cerebrum: the Dana Forum on Brain Science
https://www.readbyqxmd.com/read/27408677/imaging-the-neural-symphony
#3
Karel Svoboda
Since the start of the new millennium, a method called two-photon microscopy has allowed scientists to peer farther into the brain than ever before. Our author, one of the pioneers in the development of this new technology, writes that "directly observing the dynamics of neural networks in an intact brain has become one of the holy grails of brain research." His article describes the advances that led to this remarkable breakthrough-one that is helping neuroscientists better understand neural networks.
March 2016: Cerebrum: the Dana Forum on Brain Science
https://www.readbyqxmd.com/read/27408676/the-malignant-protein-puzzle
#4
Lary C Walker, Mathias Jucker
When most people hear the words malignant and brain, cancer immediately comes to mind. But our authors argue that proteins can be malignant too, and can spread harmfully through the brain in neurodegenerative diseases that include Alzheimer's, Parkinson's, CTE, and ALS. Studying how proteins such as PrP, amyloid beta, tau, and others aggregate and spread, and kill brain cells, represents a crucial new frontier in neuroscience.
March 2016: Cerebrum: the Dana Forum on Brain Science
https://www.readbyqxmd.com/read/27408675/david-casarett-s-stoned-a-doctor-s-case-for-medical-marijuana
#5
Bradley E Alger
With legal cannabis sales at $5.4 billion in 2015 and expected to rise by another billion this year in the United States, legalization and marijuana's impact on health is a hot topic of national debate. Casarett, a physician at the University of Pennsylvania, immerses himself in the culture, science, and smoke of medical marijuana in order to sort out the truth behind the buzz. Our reviewer, who has authored more than 120 research papers and reviews on the regulation of synaptic inhibition and endocannabinoids, tell us what the author got right, but also overlooked on his journey to learn more about a complex and controversial subject...
March 2016: Cerebrum: the Dana Forum on Brain Science
https://www.readbyqxmd.com/read/27408674/the-changing-face-of-recreational-drug-use
#6
Michael H Baumann
Our author writes that recent data from the United Nations Office of Drugs and Crime indicate that 540 different drugs classified as new psychoactive substances (NPS) have been identified worldwide as of 2014, and this number is expected to rise. His article describes the complexity of the NPS problem, what is known about the molecular mechanisms of action, and the pharmacological effects of NPS. It also highlights some of the considerable challenges in dealing with this emerging issue.
January 2016: Cerebrum: the Dana Forum on Brain Science
https://www.readbyqxmd.com/read/27408673/lithium-to-the-rescue
#7
Richard S Jope, Charles B Nemeroff
Lithium, an element that Mother Nature has put in some drinking water sources, has been used for its curative powers for centuries. Today, it's given in capsule form as a mood stabilizer for bipolar disorder and depression. New research, however, reveals its role as a neuroprotector, and suggests that a better understanding of the role enzymes modulated by lithium play could lead to new treatments for Alzheimer's disease, Parkinson's disease, multiple sclerosis, and other neurodegenerative disorders.
January 2016: Cerebrum: the Dana Forum on Brain Science
https://www.readbyqxmd.com/read/27408672/john-seamon-s-memory-movies-what-films-can-teach-us-about-memory
#8
Alan A Stone
From trauma to amnesia to senior moments, memory has been a major plot line in films since the 1942 classic, Random Harvest. John Seamon, an author and professor of psychology whose research includes how a camera aids memory and the impact of storytelling on memory, has shifted his lens to focus on how memory has been portrayed in one of the world's most beloved art forms.
January 2016: Cerebrum: the Dana Forum on Brain Science
https://www.readbyqxmd.com/read/27420921/failure-to-replicate-sound-the-alarm
#9
John P A Ioannidis
Science has always relied on reproducibility to build confidence in experimental results. Now, the most comprehensive investigation ever done about the rate and predictors of reproducibility in social and cognitive sciences has found that regardless of the analytic method or criteria used, fewer than half of the original findings were successfully replicated. While a failure to reproduce does not necessarily mean the original report was incorrect, the results suggest that more rigorous methods are long overdue...
November 2015: Cerebrum: the Dana Forum on Brain Science
https://www.readbyqxmd.com/read/27408671/review-tales-from-both-sides-of-the-brain
#10
REVIEW
Theodor Landis
Our brain has two hemispheres that specialize in different jobs-the right side processes spatial and temporal information, and the left side controls speech and language. How these two sides come together to create one mind is explained by pioneering neuroscientist Michael Gazzaniga in his new book, Tales from Both Sides of the Brain : A Life in Neuroscience (Ecco/Harper Collins, 2015). Gazzaniga is director of the SAGE Center for the Study of the Mind at the University of California, Santa Barbara, and a Dana Alliance member...
November 2015: Cerebrum: the Dana Forum on Brain Science
https://www.readbyqxmd.com/read/27408670/frances-e-jensen-s-the-teenage-brain
#11
Marisa M Silveri
The unpredictable and sometimes incomprehensible moods and behaviors of a teenager can be a head-scratching mystery-especially to parents. Hormones, boredom, social media, peer pressure, and drugs and alcohol are just a few of the factors to consider. Frances E. Jensen, M.D., professor and chair of neurology at the University of Pennsylvania and the mother of two sons who are now in their twenties (along with Washington Post health and science reporter and Pulitzer Prize winner Amy Ellis Nutt) look at the emerging science of the adolescent brain and provide advice based on Jensen's own research and experience as a single mother...
November 2015: Cerebrum: the Dana Forum on Brain Science
https://www.readbyqxmd.com/read/27408669/cognitive-skills-and-the-aging-brain-what-to-expect
#12
Diane B Howieson
Whether it's a special episode on the PBS series, "The Secret Life of the Brain" or an entire issue dedicated to the topic in the journal Science, a better understanding of the aging brain is viewed as a key to an improved quality of life in a world where people live longer. Despite dementia and other neurobiological disorders that are associated with aging, improved imaging has revealed that even into our seventies, our brains continue producing new neurons. Our author writes about how mental health functions react to the normal aging process, including why an aging brain may even form the basis for wisdom...
November 2015: Cerebrum: the Dana Forum on Brain Science
https://www.readbyqxmd.com/read/27358667/the-binge-and-the-brain
#13
Alice V Ely, Anne Cusack
Who hasn't dipped into that pint of Häagen-Dazs with the best of intentions and ended up finishing the entire container? Knowing where the line is when it comes to out-of-control impulse consumption is at the heart of binge-eating disorder (BED), a newly recognized mental condition that effects affects millions of people and that we are just beginning to better understand-from both a neurobiological and clinical standpoint.
September 2015: Cerebrum: the Dana Forum on Brain Science
https://www.readbyqxmd.com/read/27358666/no-end-in-sight-the-abuse-of-prescription-narcotics
#14
Theodore J Cicero
From teenagers dying from heroin overdoses to crime tied to Vicodin and OxyContin addiction to road fatalities in which sedatives and muscle relaxants are involved, 20,000 deaths in the United States in 2014 were attributed to problems associated with narcotics and prescription drug use. Our author, whose research involves the neurobiological basis of drug addiction, traces the history and evolution of narcotics and leans on his clinical experience to discuss why certain drugs are powerful, addicting-and dangerous...
September 2015: Cerebrum: the Dana Forum on Brain Science
https://www.readbyqxmd.com/read/27358665/review-leon-n-cooper-s-science-and-human-experience-values-culture-and-the-mind
#15
Gary S Lynch
Why are we reviewing a book written by someone who shared in the 1972 Nobel Prize in Physics for work on superconductivity? Because shortly after winning the prize, Leon N. Cooper transitioned into brain research-specifically, the biological basis of memory. He became director of the Brown University Institute for Brain and Neural Systems, whose interdisciplinary program allowed him to integrate research on the brain, physics, and even philosophy. His new book tackles a diverse spectrum of topics and questions, including these: Does science have limits? Where does order come from? Can we understand consciousness?...
July 2015: Cerebrum: the Dana Forum on Brain Science
https://www.readbyqxmd.com/read/27358664/schizophrenia-hope-on-the-horizon
#16
Patrick F Sullivan
In July 2014, an international consortium of schizophrenia researchers co-founded by the author mounted the largest biological experiment in the history of psychiatry and found eighty new regions in the genome associated with the illness. With many more avenues for exploring the biological underpinnings of schizophrenia now available to neuroscientists, hope may be on the way for the estimated 2.4 million Americans and 1 in 100 people worldwide affected by the illness, one in which drugs have limited impact and there is no known cure...
July 2015: Cerebrum: the Dana Forum on Brain Science
https://www.readbyqxmd.com/read/27358663/the-holy-grail-of-psychiatry
#17
Charles B Nemeroff
"Holy Grail" is a well-known metaphor for the eternal spiritual pursuit for truth and wisdom. It suggests that in order for us to find what no one has found, we must search where few have looked. In 2013, a group led by Helen Mayberg published a groundbreaking paper that sought an answer to one of the most discussed conundrums in psychiatry and neuroscience: Can specific patterns of brain activity indicate how a depressed person will respond to treatment with medication or psychotherapy? Our author examines the findings and discusses their potential impact on treatment for a public health problem that affects millions of people worldwide...
July 2015: Cerebrum: the Dana Forum on Brain Science
https://www.readbyqxmd.com/read/26380036/new-movement-in-neuroscience-a-purpose-driven-life
#18
Adam Kaplin, Laura Anzaldi
No abstract text is available yet for this article.
May 2015: Cerebrum: the Dana Forum on Brain Science
https://www.readbyqxmd.com/read/26380035/tau-er-of-power
#19
Kenneth S Kosik
No abstract text is available yet for this article.
May 2015: Cerebrum: the Dana Forum on Brain Science
https://www.readbyqxmd.com/read/26034529/review-power-foods-for-the-brain
#20
David O Kennedy
No abstract text is available yet for this article.
March 2015: Cerebrum: the Dana Forum on Brain Science
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