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Journal of Clinical Hypertension

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https://www.readbyqxmd.com/read/29338120/the-association-between-different-features-of-sleep-disordered-breathing-and-blood-pressure-a-cross-sectional-study
#1
Shayan Khoshkish, Mathias Hohl, Benedikt Linz, Michael Arzt, Felix Mahfoud, Mathias Baumert, Jakob Schöpe, Michael Böhm, Dominik Linz
Sleep disordered breathing (SDB) is highly prevalent in patients with high blood pressure (BP). Severity of SDB can be evaluated by the number of apneas and hypopneas per hour (AHI) or by measures of hypoxia. The objective of this study was to assess the association between different measures of SDB and BP. In 134 consecutive patients, polygraphy was performed to determine the AHI. Pulse oximetry was used to determine hypoxemic burden (time below 90% oxygen saturation [T90] and hypoxia load [HL], representing the integrated area above the curve of desaturation)...
January 16, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29338119/management-of-morning-hypertension-a-consensus-statement-of-an-asian-expert-panel
#2
REVIEW
Ji-Guang Wang, Kazuomi Kario, Chen-Huan Chen, Jeong-Bae Park, Satoshi Hoshide, Yong Huo, Hae-Young Lee, Yan Li, Masaki Mogi, Masanori Munakata, Sungha Park, Dingliang Zhu
Morning blood pressure (BP) surge is an important aspect of hypertension research. Morning BP monitoring could be a clinically relevant concept in the therapeutic management of hypertension and in the prevention of cardiovascular complications by defining and treating morning hypertension. Because antihypertensive medication is often taken in the morning, uncontrolled morning BP during the trough effect hours could be a hallmark of inadequate choice of antihypertensive regimen, such as the use of short- or intermediate-acting drugs, underdosing of drugs, or no use or underuse of combination therapy...
January 16, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29338118/impact-of-quality-of-research-on-patient-outcomes-in-the-institute-of-medicine-2013-report-on-dietary-sodium
#3
Aaron Lucko, Chelsea Ta Doktorchik, Norm Rc Campbell
The 2013 Institute of Medicine report entitled "Sodium Intake in Populations: Assessment of Evidence" found inconsistent evidence of health benefit with dietary sodium intake <2300 mg/d. Different studies reported benefit and harm of population dietary intake <2300 mg/d. The Institute of Medicine committee, however, did not assess whether the methodology used in each of the studies was appropriate to examine dietary sodium and health outcomes. This review investigates the association of methodological rigor and outcomes of studies in the Institute of Medicine report...
January 16, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29338113/efficacy-and-safety-of-sacubitril-valsartan-in-patients-with-essential-hypertension-uncontrolled-by-olmesartan-a-randomized-double-blind-8-week-study
#4
Deanna G Cheung, Diego Aizenberg, Vladimir Gorbunov, Kudsia Hafeez, Chien-Wei Chen, Jack Zhang
A majority of patients with hypertension fail to achieve blood pressure (BP) control despite treatment with commonly prescribed drugs. This randomized, double-blind phase III trial assessed the superiority of sacubitril/valsartan 200 mg (97/103 mg) to continued olmesartan 20 mg in reducing ambulatory systolic BP after 8-week treatment in patients with mild to moderate essential hypertension uncontrolled with olmesartan 20 mg alone. A total of 376 patients were randomized to receive either sacubitril/valsartan (n = 188) or olmesartan (n = 188)...
January 16, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29338112/benefits-and-pitfalls-of-sacubitril-valsartan-treatment-in-patients-with-hypertension
#5
Steven G Chrysant
No abstract text is available yet for this article.
January 16, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29338111/the-exaggerated-blood-pressure-response-to-exercise-in-the-sub-acute-phase-after-stroke-is-not-affected-by-aerobic-exercise
#6
Magnus O Wijkman, Klas Sandberg, Marie Kleist, Lars Falk, Paul Enthoven
The prevalence of an exaggerated exercise blood pressure (BP) response is unknown in patients with subacute stroke, and it is not known whether an aerobic exercise program modulates this response. The authors randomized 53 patients (27 women) with subacute stroke to 12 weeks of twice-weekly aerobic exercise (n = 29) or to usual care without scheduled physical exercise (n = 24). At baseline, 66% of the patients exhibited an exaggerated exercise BP response (peak systolic BP ≥210 mm Hg in men and ≥190 mm Hg in women) during a symptom-limited ergometer exercise test...
January 16, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29338110/is-it-time-to-utilize-measurement-of-arterial-stiffness-to-identify-and-reduce-the-risk-of-cognitive-impairment
#7
Simon W Rabkin
No abstract text is available yet for this article.
January 16, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29338106/morning-hypertension-in-asian-populations
#8
Costas Thomopoulos, Georgios Katsimagklis, Thomas Makris
No abstract text is available yet for this article.
January 16, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29334587/systolic-blood-pressure-as-a-potential-target-of-sigma-1-receptor-agonist-therapy
#9
LETTER
Jordana B Cohen, Michael L Perlis, Raymond R Townsend
No abstract text is available yet for this article.
January 15, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29329492/failure-to-confirm-high-blood-pressures-in-pediatric-care-quantifying-the-risks-of-misclassification
#10
Corinna Koebnick, Yasmina Mohan, Xia Li, Amy H Porter, Matthew F Daley, Gang Luo, Beatriz D Kuizon
Pediatric practice guidelines call for repeating an elevated office blood pressure (BP) at the same visit, but there are few data available to support this recommendation. We compared the visit results in children aged 3 to 17 years with a BP reading ≥95th percentile (n = 186 732) based on the initial BP and the mean of two BP readings, using electronic medical records from 2012-2015. Failure to repeat an initial BP reading ≥95th percentile would lead to a false "hypertensive" visit result in 54.1% of children who would require follow-up visits...
January 12, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29329483/recognizing-elevated-blood-pressure-in-pediatrics-the-value-of-repeated-measures
#11
Joshua Samuels, Cynthia Bell
No abstract text is available yet for this article.
January 12, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29316212/renal-artery-stenting-for-atherosclerotic-renal-artery-stenosis-identified-in-patients-with-coronary-artery-disease-does-captopril-renal-scintigraphy-predict-outcomes
#12
Spyros Stratigis, Kostas Stylianou, Periklis P Kyriazis, Eleftheria-Kleio Dermitzaki, Dimitra Lygerou, Paraskevi Syngelaki, Stavros Stratakis, Sophia Koukouraki, Fragiskos Parthenakis, Dimitrios Tsetis, Eugene Daphnis
The authors evaluated the effectiveness of percutaneous renal revascularization (PRR) with stenting for the treatment of atherosclerotic renal artery stenosis (ARAS) in patients with coronary artery disease and the usefulness of captopril renal scintigraphy for predicting clinical outcomes after PRR. Sixty-four consecutive patients, referred for evaluation of suspected ARAS, after coronary angiography, underwent baseline captopril renal scintigraphy followed by renal angiography. Forty-four patients (68.7%) were diagnosed with a significant ARAS≥ 60% and were treated with PRR plus medical therapy...
January 6, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29316211/prehypertension-is-a-comorbid-state-with-autonomic-and-metabolic-dysfunction
#13
Mi-Hyang Jung, Sang-Hyun Ihm, Dong-Hyeon Lee, Young Choi, Woo-Baek Chung, Hae Ok Jung, Kyung-Soon Hong, Ho-Joong Youn
We aimed to elucidate the role of autonomic dysfunction in the context of complex metabolic and cardiovascular changes in subjects with prehypertension. We identified 556 asymptomatic subjects without hypertension who underwent comprehensive cardiovascular exams. We obtained heart rate recovery (HRR) after peak exercise to quantitatively measure autonomic dysfunction. Of the 556 participants, 279 individuals had prehypertension and the remaining 277 had optimal BP. HRR was significantly lower in the prehypertension group (36...
January 6, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29316183/reliability-of-morning-before-dinner-and-at-bedtime-home-blood-pressure-measurements-in-patients-with-hypertension
#14
Takeshi Fujiwara, Satoshi Hoshide, Hiroshi Kanegae, Masafumi Nishizawa, Kazuomi Kario
The authors evaluated differences in the reliability of home blood pressure measurements taken in the morning, before dinner, and at bedtime. Forty-eight patients with hypertension (age range, 50-89 years; mean age, 76.4 years) measured their home blood pressure using a validated automatic information/communication technology-based device for 14 consecutive days. Those days were divided into the first seven days (1-7) and the following 8 to 14 days (days 8-14) and compared systolic blood pressure (SBP) reliability in the two periods for each measurement time point...
January 6, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29316154/lipid-profile-and-cytokines-in-hypertension-of-pregnancy-a-comparison-of-preeclampsia-therapies
#15
Yong Wang, Dandan Shi, Ling Chen
Hypertensive disorders complicating pregnancy can be classified as gestational hypertension, mild preeclampsia, and severe preeclampsia. It is necessary to evaluate and predict the grade in advance. The first study comprised 40 healthy pregnancies, 40 gestational hypertension, 40 mild preeclampsia, and 40 severe preeclampsia cases. The participants' lipid profile and cytokine levels were statistically compared. The efficacy and safety of oral nifedipine (n = 71) and intravenous labetalol (n = 72) for the treatment of severe preeclampsia were evaluated in the next study according to maternal and neonatal outcomes...
January 6, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29316147/dihydropyridine-calcium-channel-blockers-in-the-elderly-with-diabetic-nephropathy-are-they-safe
#16
LETTER
Zeid J Khitan, Antonios H Tzamaloukas, Sergey Brodsky, Joseph I Shapiro
No abstract text is available yet for this article.
January 6, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29316126/fixed-dose-combination-therapy-to-reduce-the-growing-burden-of-cardiovascular-disease-in-low-and-middle-income-countries-feasibility-and-challenges
#17
REVIEW
Jobert Richie Nansseu, Aurel T Tankeu, Joseph Kamtchum-Tatuene, Jean Jacques Noubiap
Cardiovascular disease (CVD) has become a major concern in low- and middle-income countries, which bear about 80% of the cardiovascular mortality worldwide. Curbing the burden of CVD implies the management and control of many cardiovascular risk factors that act synergistically to increase cardiovascular mortality. Such actions may require expensive polymedications in a context of limited resources. Therefore, alternative solutions for CVD prevention in low- and middle-income countries are urgently needed. In this context, the concept of a fixed-dose combination therapy, a polypill composed of drugs known to effectively treat or prevent CVD, has been proposed as a scalable strategy to overcome nonadherence to polymedications and reduce costs...
January 6, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29316224/resistant-hypertension-a-therapeutic-challenge
#18
Laura Brandani
No abstract text is available yet for this article.
January 5, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29316213/comparative-effects-of-valsartan-plus-either-cilnidipine-or-hydrochlorothiazide-on-home-morning-blood-pressure-surge-evaluated-by-information-and-communication-technology-based-nocturnal-home-blood-pressure-monitoring
#19
Takeshi Fujiwara, Naoko Tomitani, Hiroshi Kanegae, Kazuomi Kario
The authors tested the hypothesis that a valsartan/cilnidipine combination would suppress the home morning blood pressure (BP) surge (HMBPS) more effectively than a valsartan/hydrochlorothiazide combination in patients with morning hypertension, defined as systolic BP (SBP) ≥135 mm Hg or diastolic BP ≥85 mm Hg assessed by a self-measuring information and communication technology-based home BP monitoring device more than three times before either combination's administration. This was an 8-week prospective, multicenter, randomized, open-label clinical trial...
January 5, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29316186/organ-damage-changes-in-patients-with-resistant-hypertension-randomized-to-renal-denervation-or-spironolactone-the-denervhta-denervaci%C3%A3-n-en-hipertensi%C3%A3-n-arterial-study
#20
Anna Oliveras, Pedro Armario, Laia Sans, Albert Clarà, Susana Vázquez, Luis Molina, Júlia Pareja, Alejandro de la Sierra, Julio Pascual
Renal denervation and spironolactone have both been proposed for the treatment of resistant hypertension, but their effects on preclinical target organ damage have not been compared. Twenty-four patients with 24-hour systolic blood pressure ≥140 mm Hg despite receiving three or more full-dose antihypertensive drugs, one a diuretic, were randomized to receive spironolactone or renal denervation. Changes in 24-hour blood pressure, urine albumin excretion, arterial stiffness, carotid intima-media thickness, and left ventricular mass index were evaluated at 6 months...
January 5, 2018: Journal of Clinical Hypertension
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