journal
MENU ▼
Read by QxMD icon Read
search

Breast Cancer: the Journal of the Japanese Breast Cancer Society

journal
https://www.readbyqxmd.com/read/30218304/surgical-and-oncological-safety-of-nipple-sparing-mastectomy-in-an-asian-population
#1
Yvonne Ying-Ru Ng, Veronique Kiak-Mien Tan, Wan Sze Pek, Jasmine Hui-Er Chang, Yirong Sim, Kong Wee Ong, Wei Sean Yong, Preetha Madhukumar, Chow Yin Wong, Yee Siang Ong, Bien Keem Tan, Benita Kiat Tee Tan
BACKGROUND: Nipple-sparing mastectomy (NSM) allows for excellent postmastectomy reconstruction aesthetics and is used for both therapeutic and risk-reducing purposes. Reservations regarding the potential for locoregional recurrence and concerns about nipple-areolar complex (NAC) necrosis remain amongst many surgeons. We review the surgical and oncological outcomes after NSM in our institution. METHODS: All NSM cases at the National Cancer Centre Singapore and Singapore General Hospital between 2005 and 2015 were reviewed...
September 14, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/30209686/expression-of-the-rac1-rhoa-and-cxcr4-proteins-and-their-interaction-as-risk-factors-for-infiltration-to-the-nipple-areola-complex-in-operable-breast-carcinoma
#2
Yusuf Heriady, Dimyati Achmad, Bethy S Hernowo, Ahmad Faried, Darmadji Ismono, Dany Hilmanto
BACKGROUND: Nipple areola complex (NAC) infiltration in operable breast carcinoma (OBC) is associated with local recurrence. NAC infiltration in OBC suggests that RAC1, RHOA and CXCR4 proteins are risk factors for migration and infiltration of OBC to NAC. This study aims to analyze the expression and interactions of these proteins as risk factors for NAC infiltration in OBC. MATERIALS AND METHODS: This is an analytic observational cross-sectional study coupled with a categorical comparative study in each 40 subjects of OBC with and without NAC infiltration...
September 12, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/30194662/evaluation-of-health-related-quality-of-life-via-the-computer-based-health-evaluation-system-ches-for-japanese-metastatic-breast-cancer-patients-a-single-center-pilot-study
#3
Yuichiro Kikawa, Yukimasa Hatachi, Gerhard Rumpold, Mariko Tokiwa, Sayaka Takebe, Takatsugu Ogata, Hironaga Satake, Hironori Kato, Akihito Tsuji, Hisateru Yasui, Bernhard Holzner
BACKGROUND: The main purposes of metastatic breast cancer (MBC) treatment are to prolong survival and maintain health-related quality of life (HRQOL). Compliance with the HRQOL assessment can be poor, particularly among patients who receive long-term treatment. One possible solution to overcoming this problem is to engage in real-time home monitoring by having patients report outcomes on their personal electronic devices. The objective of this study was to investigate compliance with HRQOL monitoring from home among MBC patients using the Computer-Based Health Evaluation System (CHES) to collect patient data...
September 7, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/30191397/chemotherapy-and-targeted-therapy-for-breast-cancer-patients-with-hepatitis-c-virus-infection
#4
Soha Talima, Hebatallah Kaseem, Nemaat Kaseem
BACKGROUND: Hepatitis C virus infection (HCV) is a major health problem in Egypt. Breast cancer is the most common cancer among Egyptian women. Considering that both diseases are frequent in the Egyptian population, it is likely that many women are affected by both. PURPOSE: To evaluate patient safety and applicability of chemotherapy in chronic hepatitis C virus-infected patients with breast cancer. SUBJECTS AND METHODS: We performed retrospective survey of 58 Egyptian patients diagnosed with both diseases...
September 6, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/30182250/breast-cancer-patients-with-brain-metastasis-undergoing-gkrs
#5
Maysa Abu-Khalaf, Sivraj Muralikrishnan, Christos Hatzis, Deepti Canchi, James B Yu, Veronica Chiang
BACKGROUND: Breast cancer (BC) is the second most common cause of brain metastasis in the United States. Compared to whole brain radiation therapy (WBRT), treatment with gamma-knife radiosurgery (GKRS) offers a better chance at neurocognitive preservation. The goal of our retrospective study is to report the overall survival (OS) in patients receiving GKRS and to identify factors that improve survival outcomes. METHODS: The records of 80 patients with primary BC treated with GKRS at the Yale Comprehensive Cancer Center between 2000 and 2013 were reviewed...
September 4, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/30151780/fat-necrosis-after-breast-conserving-oncoplastic-surgery
#6
Haruka Nakada, Masayuki Inoue, Kazushige Furuya, Hideki Watanabe, Kou Ikegame, Yuko Nakayama, Masato Ohmori, Hiroshi Nakagomi
BACKGROUND: Fat necrosis is a subjective early as well as delayed complication, which sometimes mimics local recurrence and ruins the quality of life by pain and poor cosmetic result. While, the frequency and severity of fat necrosis are important issues that breast surgeons should explain to the patient, these data are not revealed well. METHODS: A total of 1476 patients who underwent breast surgery from January 2000 to December 2012 were enrolled in the present study...
August 27, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/30136077/exposure-to-violence-in-breast-cancer-patients-systematic-review
#7
REVIEW
Dilek Aygin, Havva Bozdemir
RESULTS: The nine studies included were reviewed under two titles as descriptive and qualitative. Based on the results of six descriptive studies, it was determined that the majority of these studies focused on violence and abuse in childhood; depression is high among breast cancer patients exposed to violence; healing is unfavorably influenced among breast cancer patients exposed to spouse violence or abuse/violence in childhood; physical, emotional and functional welfare/comforts are restricted and quality of life is low during disease process; there is positive correlation between advanced-stage cancer and history of violence; they hesitate to ask the clinical staff for support...
August 22, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/30069785/histogram-analysis-of-quantitative-pharmacokinetic-parameters-on-dce-mri-correlations-with-prognostic-factors-and-molecular-subtypes-in-breast-cancer
#8
Ken Nagasaka, Hiroko Satake, Satoko Ishigaki, Hisashi Kawai, Shinji Naganawa
BACKGROUND: Breast cancer heterogeneity influences poor prognoses thorough therapy resistance. This study quantitatively evaluated intratumoral heterogeneity through a histogram analysis of dynamic contrast-enhanced MRI (DCE-MRI) pharmacokinetic parameters, and determined correlations with prognostic factors and molecular subtypes. METHODS: We retrospectively investigated 101 invasive ductal breast cancers from 99 women who underwent preoperative DCE-MRI between July 2012 and November 2014...
August 1, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/30066060/oestrogen-receptor-negative-progesterone-receptor-positive-phenotype-of-invasive-breast-carcinoma-in-japan-re-evaluated-using-immunohistochemical-staining
#9
Hajime Kuroda, Nozomi Muroi, Mitsuhiro Hayashi, Oi Harada, Kazuei Hoshi, Eisuke Fukuma, Akihito Abe, Keiichi Kubota, Yasuo Imai
BACKGROUND: The existence of progesterone receptor (PgR) expression in oestrogen receptor (ER)-negative breast carcinoma is controversial. Here, we re-evaluated ER-negative/PgR-positive (ER-/PgR+) carcinoma cases by immunohistochemical staining (IHC). MATERIALS AND METHODS: We selected patients who underwent surgery for primary breast carcinoma from our databases at Dokkyo Medical University Hospital and Kameda General Hospital. Among the 9844 patients, the largest series in Japan, 27 (0...
July 31, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/30056526/younger-breast-cancer-patients-under-the-age-of-35-might-have-a-better-disease-free-survival-if-they-received-ovarian-function-suppression-more-than-3-years
#10
LETTER
Kadri Altundag
No abstract text is available yet for this article.
July 28, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/30054855/effect-of-denosumab-on-low-bone-mineral-density-in-postmenopausal-japanese-women-receiving-adjuvant-aromatase-inhibitors-for-non-metastatic-breast-cancer-24-month-results
#11
Katsuhiko Nakatsukasa, Hiroshi Koyama, Yoshimi Ouchi, Hisako Ono, Kouichi Sakaguchi, Takayuki Matsuda, Makoto Kato, Takashi Ishikawa, Kimito Yamada, Mana Yoshimura, Kei Koizumi, Teruhisa Sakurai, Hideo Shigematsu, Shunji Takahashi, Shinichiro Taira, Masato Suzuki, Kazutaka Narui, Naoki Niikura, Yoshie Hasegawa, Daishu Miura, Eiichi Konishi, Tetsuya Taguchi
BACKGROUND: Aromatase inhibitors (AI) have been established as the gold-standard therapy for postmenopausal patients. Worldwide, adjuvant denosumab at a dose of 60 mg twice per year reduces the risk of clinical fractures in postmenopausal patients with breast cancer who received AI. However, the efficacy of denosumab in the treatment of AI-associated bone loss had not been prospectively evaluated in Japan. Previously, we reported the 12-month effect of denosumab in Japanese patients for the first time; the primary endpoint was the change in the percentage of bone mineral density (BMD) of the lumbar spine from baseline to 12 months...
July 27, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/30039340/cdkn2a-p16ink4a-variants-association-with-breast-cancer-and-their-in-silico-analysis
#12
REVIEW
Ayesha Aftab, Shaheen Shahzad, Hafiz Muhammad Jafar Hussain, Ranjha Khan, Samra Irum, Sobia Tabassum
CDKN2A was first identified as melanoma predisposition tumour suppressor gene and has been successively studied. The previous researches have not established any noteworthy association with breast cancer. Therefore, through extensive literature search and in-silico analysis, we have tried to focus on the role of CDKN2A in breast cancer. CDKN2A variants in breast cancer were collected from different databases. The overall percentage of variants (approximately 5.8%) and their incidence frequency in breast cancer cases were found to be very low as compared to the number of samples screened in different studies...
July 23, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/30039339/trastuzumab-emtansine-plus-pertuzumab-in-japanese-patients-with-her2-positive-metastatic-breast-cancer-a-phase-ib-study
#13
Emi Noguchi, Kenji Tamura, Masaya Hattori, Jun Horiguchi, Nobuaki Sato, Kazumitsu Kanatani, Kiyoshi Matsunaga, Hiroji Iwata, Yasuhiro Fujiwara
PURPOSE: To investigate the safety, pharmacokinetics, and efficacy of trastuzumab emtansine (T-DM1) in combination with pertuzumab in Japanese patients with human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer. PATIENTS AND METHODS: Patients with HER2-positive advanced or recurrent breast cancer who had received trastuzumab and chemotherapy-containing therapies were eligible. Patients received T-DM1 (3.6 mg/kg) with full-dose pertuzumab (a loading dose of 840 mg and then 420 mg) intravenously every 3 weeks...
July 23, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/30027391/could-sentinel-lymph-node-biopsy-be-exempted-for-ductal-carcinoma-in-situ-after-mastectomy
#14
LETTER
Jiqiao Yang, Qing Lv
No abstract text is available yet for this article.
July 19, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/30022435/quantitative-proteome-and-lysine-succinylome-analyses-provide-insights-into-metabolic-regulation-in-breast-cancer
#15
Chenchen Liu, Ying Liu, Lei Chen, Mingjun Zhang, Wei Li, Huaidong Cheng, Bo Zhang
BACKGROUND: Breast cancer, the most common invasive cancer and cause of cancer-related death in women worldwide, is a multifactorial, complex disease, and many molecular players and mechanisms underlying the complexity of its clinical behavior remain unknown. METHODS: To explore the molecular features of breast cancer, quantitative proteome and succinylome analyses in breast cancer were extensively studied using quantitative proteomics techniques, anti-succinyl lysine antibody-based affinity enrichment, and high-resolution LC-MS/MS analysis...
July 18, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/30019283/oncoplastic-approach-to-excisional-breast-biopsies-a-randomized-controlled-phase-2a-trial
#16
Volkan Doğru, Muhittin Yaprak, Emel Durmaz, Özlenen Özkan, Ayhan Mesci, Ömer Özkan, Vahit Özmen, Cumhur Arıcı
BACKGROUND: Oncoplastic surgery has been used in breast cancer patients for better cosmetic outcome over the last decades. The aim of this prospective randomized study is to show its place in excisional breast biopsy. METHODS: An oncoplastic approach excision was compared with conventional excisional breast biopsies. The study included 80 patients, of whom half received oncoplastic intervention and half received the conventional. The primary endpoint was the cosmetic result...
July 17, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/29992486/effects-of-a-combined-exercise-plus-diet-program-on-cardiorespiratory-fitness-of-breast-cancer-patients
#17
K Okumatsu, T Tsujimoto, K Wakaba, A Seki, R Kotake, T Yamauchi, S Hirayama, H Kobayashi, H Yamauchi, K Tanaka
BACKGROUND: Decreases in cardiorespiratory fitness among breast cancer patients have often been reported in previous studies, affecting patients' health and survival. Peak oxygen uptake ([Formula: see text]) is the gold standard for assessing cardiorespiratory fitness and is inversely correlated with cardiovascular disease among women with breast cancer. Some previous studies have reported that aerobic exercise and proper diet positively influence [Formula: see text]. However, almost all studies have been conducted in the Western countries, and few studies are investigating on Asian women who have lower BMI compared with Western ones...
July 10, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/29981009/quantitative-assessment-and-risk-factors-for-nipple-areolar-complex-malposition-after-nipple-sparing-mastectomy
#18
Takaya Makiguchi, Hideharu Nakamura, Takaaki Fujii, Satoshi Yokoo
PURPOSE: Nipple sparing mastectomy (NSM) for breast cancer preserves the nipple-areola complex (NAC) and has limited the extent of the scar, giving good cosmetic results. However, NAC malposition may occur. The aim of this study is to evaluate NAC malposition after NSM and to determine factors associated with malposition in two-stage reconstruction. METHODS: The subjects were 46 patients who underwent unilateral NSM, without contralateral mastopexy or reduction surgery, in two-stage reconstruction using an expander with implant or flap replacement...
July 6, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/29974352/up-regulated-lncrna-afap1-as1-indicates-a-poor-prognosis-and-promotes-carcinogenesis-of-breast-cancer
#19
Dachang Ma, Cheng Chen, Jun Wu, Honglei Wang, Duoming Wu
BACKGROUND: Long noncoding RNAs (lncRNAs) have been reported to play crucial roles in breast cancer. This study aimed to determine the clinical significance and biological functions of lncRNA AFAP1-AS1 in breast cancer. METHODS: The expression of AFAP1-AS1 in breast cancer tissue and adjacent normal tissue from 160 patients and breast cancer cell lines were determined by qRT-PCR. The clinical characteristics of patients were collected to analyse the correlation between AFAP1-AS1 expression and malignancy status...
July 5, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/29971631/cd44v9-as-a-poor-prognostic-factor-of-triple-negative-breast-cancer-treated-with-neoadjuvant-chemotherapy
#20
Eriko Tokunaga, Aya Fujita, Katsumi Takizawa, Kimiko Baba, Sayuri Akiyoshi, Yoshiaki Nakamura, Hideki Ijichi, Takanobu Masuda, Chinami Koga, Wakako Tajiri, Shinji Ohno, Kenichi Taguchi, Mayumi Ishida
BACKGROUND: Neoadjuvant chemotherapy (NAC) is the standard therapeutic strategy for triple-negative breast cancer (TNBC). TNBC patients with residual disease after NAC have a significantly worse survival than those with pathological complete response (pCR); however, there is no apparent prognostic factor for non-pCR patients. Cancer stemness or epithelial-mesenchymal transition (EMT) might influence the sensitivity to chemotherapy. PATIENTS AND METHODS: Forty-eight patients with TNBC who were treated with NAC were available were included in this study...
July 3, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
journal
journal
34671
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"