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Breast Cancer: the Journal of the Japanese Breast Cancer Society

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https://www.readbyqxmd.com/read/27896661/erratum-to-breast-reconstruction-using-free-medial-circumflex-femoral-artery-perforator-flaps-intraoperative-anatomic-study-and-clinical-results
#1
Mai Shibuya, Toshihiko Satake, Reiko Nakasone, Marina Ogawa, Mayu Muto, Kazutaka Narui, Kazunori Yasumura, Takashi Ishikawa, Jiro Maegawa
No abstract text is available yet for this article.
November 28, 2016: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/27882505/antitumor-immunity-and-advances-in-cancer-immunotherapy
#2
EDITORIAL
Tomoharu Sugie, Masakazu Toi
No abstract text is available yet for this article.
November 23, 2016: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/27878697/nf%C3%AE%C2%BAbp65-transcription-factor-modulates-resistance-to-doxorubicin-through-abc-transporters-in-breast-cancer
#3
Kobra Velaei, Nasser Samadi, Sina Soltani, Balal Barazvan, Jafar Soleimani Rad
BACKGROUND: Shedding light on chemoresistance biology of breast cancer could contribute to enhance the clinical outcome. Intrinsic or acquired resistance to chemotherapy is a major problem in breast cancer treatment. METHODS AND MATERIALS: The NFκB pathway by siRNAP65 and JSH-23 as a translocational inhibitor of NFκBP65 in the doxorubicin-resistant MCF-7 (MCF-7/Dox) and MCF-7 cells was blocked. Then, the ABC transporter expression and function were assessed by real-time qRT-PCR and flow cytometry, respectively...
November 23, 2016: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/27878446/accuracy-assessment-methods-of-tissue-marker-clip-placement-after-11-gauge-vacuum-assisted-stereotactic-breast-biopsy-comparison-of-measurements-using-direct-and-conventional-methods
#4
Hidetoshi Yatake, Yuka Sawai, Toshio Nishi, Yoshiaki Nakano, Ayaka Nishimae, Toshizo Katsuda, Koichi Yabunaka, Yoshihiro Takeda, Hideo Inaji
BACKGROUND: The objective of the study was to compare direct measurement with a conventional method for evaluation of clip placement in stereotactic vacuum-assisted breast biopsy (ST-VAB) and to evaluate the accuracy of clip placement using the direct method. METHODS: Accuracy of clip placement was assessed by measuring the distance from a residual calcification of a targeted calcification clustered to a clip on a mammogram after ST-VAB. Distances in the craniocaudal (CC) and mediolateral oblique (MLO) views were measured in 28 subjects with mammograms recorded twice or more after ST-VAB...
November 22, 2016: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/27873170/overcalling-low-risk-findings-grouped-amorphous-calcifications-found-at-screening-mammography-associated-with-minimal-cancer-risk
#5
Madoka Iwase, Hiroko Tsunoda, Kanako Nakayama, Emiko Morishita, Naoki Hayashi, Koyu Suzuki, Hideko Yamauchi
BACKGROUND: Because of the increasing availability of screening mammography and spread of information about its benefits, the incidence of early breast cancer has been increasing in Japan. However, screening mammography can result in overdiagnoses or false positives, causing in some subjects undergoing unnecessary invasive procedures. The current mammography guidelines recommend further investigation of subjects with grouped amorphous calcifications; this recommendation may have resulted in overdiagnoses or false positives...
November 21, 2016: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/27848085/long-non-coding-rna-tug1-promotes-cell-proliferation-and-metastasis-in-human-breast-cancer
#6
Teng Li, Yun Liu, Haifeng Xiao, Guanghui Xu
BACKGROUND: Long non-coding RNAs (LncRNAs) utilize a wide variety of mechanisms to regulate RNAs or proteins on the transcriptional or post-transcriptional levels. Accumulating studies have identified numerous LncRNAs to exert critical effects on different physiological processes, genetic disorders, and human diseases. MATERIALS AND METHODS: Both clinical tissues from breast cancer patients and cultured cells were used for the qRT-PCR analysis. Specific siRNAs were included to assess the roles of TUG1 with cell viability assay, transwell assay, and cell apoptosis assay, respectively...
November 15, 2016: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/27838870/evaluation-of-the-sonographic-visibility-and-sonographic-appearance-of-the-breast-biopsy-marker-ultraclip-%C3%A2-placed-in-phantoms-and-patients
#7
Naomi Sakamoto, Yukari Ogawa, Yuko Tsunoda, Eisuke Fukuma
PURPOSE: To evaluate the usefulness of the UltraClip(®) dual trigger breast tissue marker (UltraClip) for sonographic localization, we investigate the sonographic visibility and sonographic appearance of the UltraClip placed in phantoms and patients. MATERIALS AND METHODS: Ten UltraClips were placed in the target lesions in the phantoms. After the ultrasound examination of the UltraClip, the ultrasound images were compared to the real appearance of the UltraClip obtained by cutting the phantoms...
November 12, 2016: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/27837442/non-calcified-ductal-carcinoma-in-situ-of-the-breast-comparison-of-diagnostic-accuracy-of-digital-breast-tomosynthesis-digital-mammography-and-ultrasonography
#8
Xiaohui Su, Qing Lin, Chunxiao Cui, Wenjian Xu, Zhimin Wei, Jie Fei, Lili Li
BACKGROUND: To retrospectively compare the diagnostic accuracy of digital breast tomosynthesis (DBT), digital mammography (DM), and ultrasonography (US) in non-calcified ductal carcinoma in situ (DCIS, include DCIS with micro-invasion). PATIENTS AND METHODS: Ninety-eight patients with non-calcified DCIS (include DCIS with micro-invasion) were enrolled in our study. Breast carcinoma in situ was confirmed by surgical pathologic evaluation. Our Institutional Review Board granted approval and the participating women provided written informed consent...
November 11, 2016: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/27837441/tp53-codon-72-polymorphism-and-breast-cancer-risk-in-bangladeshi-population
#9
Amir Hossain, Gazi Md Monjur Murshid, Md Nazmul Hasan Zilani, Fahrima Islam, Razia Sultana, Tamanna Sultana, Md Golam Hossain, Md Mustafizur Rahman
BACKGROUND: Breast cancer, a hereditary or heterogeneous sporadic disease, is the most common cancer in women worldwide. The tumor suppressor TP53 gene has been found to be the most commonly mutated genes in many types of human cancers, including breast cancer. This study aimed to investigate the association of codon 72 polymorphism of TP53 gene with breast cancer risk in Bangladeshi females. METHODS: The study included 125 cases and 125 healthy controls. Genotyping and polymorphism were determined by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis...
November 11, 2016: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/27812996/effect-of-the-childhood-trauma-on-the-adjustment-to-cancer-in-the-patients-with-breast-cancer
#10
Hulya Guveli, Murat Emin Guveli, Fatma Sen, Serap Oflaz, Necla Gurdal, Makbule Tambas, Seden Kucucuk, Adnan Aydıner, Mine Ozkan
BACKGROUND: Early identification of patients coping poorly is important for compliance with treatment and control of distress. This study aims to investigate the effect of the childhood trauma experience on the type of reaction and adjustment that the person exhibits to the cancer among the patients with breast cancer. METHODS: This cross-sectional study enrolled 310 patients with breast cancer. The effect of the childhood trauma and the psychological condition on the adjustment to cancer was investigated by assessing the adjustment to cancer, the experiences of childhood trauma and psychological status of the subjects using mental adjustment to cancer scale (MAC), childhood trauma questionnaire (CTQ28), Beck Depression Inventory (BDI) and Beck anxiety inventory (BAI)...
November 3, 2016: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/27796923/recent-development-of-targeted-approaches-for-the-treatment-of-breast-cancer
#11
V L Maruthanila, R Elancheran, A B Kunnumakkara, S Kabilan, Jibon Kotoky
Breast cancer is the most prominent cause of cancer death in women worldwide. The highlights of this review are to provide an overview of the targeted therapeutic agents, challenges with metastatic breast cancer (MBCa), mechanisms of action through Hedgehog/Gli 1 signaling pathway and future prospective. Over a decade of success, several drugs have been approved and are in the advanced stages of clinical trials that target the receptors such as estrogen receptor, growth factor receptor, receptor activator of nuclear factor kappa-B, etc...
October 31, 2016: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/27730528/body-mass-index-and-menopausal-disorders-during-menopause-affect-vasomotor-symptoms-of-postmenopausal-japanese-breast-cancer-patients-treated-with-anastrozole-a-prospective-multicenter-cohort-study-of-patient-reported-outcomes
#12
Kaori Tane, Chiyomi Egawa, Shintaro Takao, Kazuhiko Yamagami, Masaru Miyashita, Masashi Baba, Shigetoshi Ichii, Muneharu Konishi, Yuichiro Kikawa, Junya Minohata, Toshitaka Okuno, Keisuke Miyauchi, Kazuyuki Wakita, Hirofumi Suwa, Takashi Hashimoto, Masayuki Nishino, Takashi Matsumoto, Toshiharu Hidaka, Yutaka Konishi, Yoko Sakoda, Akihiro Miya, Masahiro Kishimoto, Hidefumi Nishikawa, Seishi Kono, Ikuo Kokufu, Isao Sakita, Koushiro Kitatsuji, Koushi Oh, Kouhei Akazawa, Yasuo Miyoshi
BACKGROUND: Adverse events related to endocrine therapies have a major impact not only on patients' quality of life but also on treatment discontinuation. Although vasomotor symptoms induced by aromatase inhibitors are frequently recognized, risk factors, especially for Japanese women, are not well reported. To identify risk factors for vasomotor symptoms of Japanese breast cancer patients treated with adjuvant anastrozole, we conducted a prospective cohort study based on patient-reported outcomes (PROs)...
October 12, 2016: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/27730527/erratum-to-genetic-variants-of-esr1-and-sgsm3-are-associated-with-the-susceptibility-of-breast-cancer-in-the-chinese-population
#13
Tan Tan, Kai Zhang, Wenjun Chen
No abstract text is available yet for this article.
October 11, 2016: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/27709424/gastrointestinal-microbiome-and-breast-cancer-correlations-mechanisms-and-potential-clinical-implications
#14
Jiqiao Yang, Qiuwen Tan, Qingyu Fu, Yaojie Zhou, Yuanyuan Hu, Shenli Tang, Yuting Zhou, Junhui Zhang, Juanjuan Qiu, Qing Lv
Gastrointestinal microbiome plays as a symbiont which provides protection effect against invading pathogens, aids in the immune system development, nutrient reclamation and absorption as well as molecule breakdown. And it may avert carcinogenesis through these biological activities. By now, studies have been carried out to elaborate the association between gastrointestinal microbiome and breast cancer. It has been implicated that breast cancer was substantially associated with estrogen-dependent and estrogen-independent functions of gastrointestinal microbiome...
October 5, 2016: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/27687626/a-study-of-tumor-heterogeneity-in-a-case-with-breast-cancer
#15
Haruka Nakada, Hiroshi Nakagomi, Yosuke Hirotsu, Kenji Amemiya, Hitoshi Mochizuki, Masayuki Inoue, Toshio Oyama, Masao Omata
Tumor heterogeneity has been suggested based on clinical and pathological findings. Several clinical findings can be explained by tumor evolution during progression and metastasis. We herein report a case of metastatic breast cancer indicated tumor heterogeneity by clinical findings and a genomic analysis. A 64-year-old woman with advanced breast cancer was treated with primary chemotherapy, to which primary tumor responded. After a 6 month treatment pause, lung, liver, and skin metastases developed and her serum tumor markers were elevated...
September 29, 2016: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/27639877/mammographic-extent-of-microcalcifications-and-oestrogen-receptor-expression-affect-preoperative-breast-carcinoma-in-situ-size-estimation
#16
Maria Vernet-Tomas, Sergi Mojal, Rocío Gamero, Pau Nicolau, Ana Rodríguez-Arana, Francisco Plancarte, Josep M Corominas, Laia Serrano-Munne, Ramon Carreras, Dolors Sabadell
BACKGROUND: The aim of our study was to establish which clinical, radiologic and pathologic factors could predict the risk of under- and overestimation of the breast ductal carcinoma in situ (DCIS) size when preoperatively measuring the maximum mammographic extent of microcalcifications (MEM). METHODS: We made a retrospective review of patients with a DCIS treated in our Breast Unit between May 2005 and May 2012. Clinical, pathologic and radiologic data were evaluated as possible predictive factors for over- or underestimation of DCIS size when measuring MEM...
September 17, 2016: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/27628678/post-relapse-survival-in-patients-with-the-early-and-late-distant-recurrence-in-estrogen-receptor-positive-her2-negative-breast-cancer
#17
Akiko Ogiya, Kieko Yamazaki, Rie Horii, Tadahiko Shien, Yoshiya Horimoto, Norikazu Masuda, Touko Inao, Mitsuchika Hosoda, Naoko Ishida, Tomofumi Osako, Masato Takahashi, Yumi Endo, Yuichiro Miyoshi, Hiroyuki Yasojima, Nobumoto Tomioka, Hiroko Yamashita
BACKGROUND: Few studies have been performed on post-relapse survival in patients with the early and late distant recurrence in estrogen receptor (ER)-positive, HER2-negative breast cancer. METHODS: A total of 205 patients with the early distant recurrence and 134 patients with the late distant recurrence of ER-positive, HER2-negative breast cancer who had undergone breast surgery or neoadjuvant chemotherapy between January 2000 and December 2004 were registered from nine institutions...
September 15, 2016: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/27624602/breast-reconstruction-using-free-medial-circumflex-artery-perforator-flaps-intraoperative-anatomic-study-and-clinical-results
#18
Mai Shibuya, Toshihiko Satake, Reiko Nakasone, Marina Ogawa, Mayu Muto, Kazutaka Narui, Kazunori Yasumura, Takashi Ishikawa, Jiro Maegawa
BACKGROUND: A free fascioadipocutaneous flap obtained from the medial thigh is suitable for breast reconstruction in Asian women with a small-to-moderate breast size. In this region, both a medial circumflex femoral artery perforator flap (MCFAp flap) and a posterior medial thigh perforator flap (PMTp flap) are options, based on perforators from the deep femoral vessels. Here, we evaluated the anatomic basis of the medial circumflex femoral artery (MCFA) perforators from the medial circumflex femoral vessels...
September 13, 2016: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/27605223/possible-supplemental-breast-cancer-screening-modalities
#19
Takayoshi Uematsu
No abstract text is available yet for this article.
September 7, 2016: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/27600636/current-trends-and-outcomes-of-breast-reconstruction-following-nipple-sparing-mastectomy-results-from-a-national-multicentric-registry-with-1006-cases-over-a-6-year-period
#20
Donato Casella, Claudio Calabrese, Lorenzo Orzalesi, Ilaria Gaggelli, Lorenzo Cecconi, Caterina Santi, Roberto Murgo, Stefano Rinaldi, Lea Regolo, Claudio Amanti, Manuela Roncella, Margherita Serra, Graziano Meneghini, Massimiliano Bortolini, Vittorio Altomare, Carlo Cabula, Francesca Catalano, Alfredo Cirilli, Francesco Caruso, Maria Grazia Lazzaretti, Icro Meattini, Lorenzo Livi, Luigi Cataliotti, Marco Bernini
BACKGROUND: Reconstruction options following nipple-sparing mastectomy (NSM) are diverse and not yet investigated with level IA evidence. The analysis of surgical and oncological outcomes of NSM from the Italian National Registry shows its safety and wide acceptance both for prophylactic and therapeutic cases. A further in-depth analysis of the reconstructive approaches with their trend over time and their failures is the aim of this study. METHODS: Data extraction from the National Database was performed restricting cases to the 2009-2014 period...
September 6, 2016: Breast Cancer: the Journal of the Japanese Breast Cancer Society
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