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Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine

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https://www.readbyqxmd.com/read/29458325/comparison-of-continuous-wave-doppler-ultrasound-monitor-and-echocardiography-to-assess-cardiac-output-in-intensive-care-patients
#1
Brendan E Smith, Veronica M Madigan
No abstract text is available yet for this article.
March 2018: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/29458324/smoking-cessation-therapy-in-australian-and-new-zealand-intensive-care-units-a-multicentre-point-prevalence-study
#2
Forbes McGain, Matthew L Durie, Samantha Bates, Christine M Polmear, Jason Meyer, Craig J French
OBJECTIVE: To obtain an accurate estimate of smoking prevalence and smoking cessation support practices, including nicotine replacement therapy (NRT), in Australian and New Zealand intensive care units (ICUs). DESIGN, SETTING AND PARTICIPANTS: Cross-sectional, observational study using data obtained from adult ICUs participating in the Australian and New Zealand Intensive Care Society Clinical Trials Group Point Prevalence Program in 2016. MAIN OUTCOME MEASURES: Prevalence and intensity of current smoking, baseline characteristics of smokers in comparison with non-smokers and frequency of NRT use while admitted to the ICU...
March 2018: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/29458323/a-randomised-controlled-trial-to-determine-the-effectiveness-of-a-radial-arterial-catheter-dressing
#3
Clare Healy, Ian Baldwin, Judy Currey, Andrea Driscoll
OBJECTIVE: To reduce radial arterial catheter failure in patients admitted to an adult intensive care unit (ICU). DESIGN: A randomised controlled trial. SETTING: A single site, large metropolitan tertiary referral public hospital. PARTICIPANTS: Three hundred participants admitted to an adult ICU were enrolled between 25 May and 13 September 2015. INTERVENTIONS: Participants were randomly assigned to one of two treatment groups (a polyurethane adhesive keyhole dressing or a polyurethane adhesive keyhole dressing together with a polyurethane semipermeable transparent dressing)...
March 2018: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/29458322/predicting-recovery-from-acute-kidney-injury-in-critically-ill-patients-development-and-validation-of-a-prediction-model
#4
Theis S Itenov, Rasmus Ehrenfried Berthelsen, Jens-Ulrik Jensen, Thomas A Gerds, Lars M Pedersen, Ditte Strange, Katrin Thormar, Jesper Løken, Mads H Andersen, Hamid Tousi, Nanna Reiter, Jens D Lundgren, Morten H Bestle
OBJECTIVE: Intensive care unit (ICU) patients with acute kidney injury (AKI) who recover kidney function within 28 days experience less severe chronic kidney impairment and have increased long term survival. The aims of this study were to develop and validate a risk prediction model to identify these patients. DESIGN: Observational study with development and validation of a risk prediction model. SETTING: Nine academic ICUs in Denmark. PARTICIPANTS: Development cohort of critically ill patients with AKI at ICU admission from the Procalcitonin and Survival Study cohort (n = 568), validation cohort of adult patients with AKI admitted to two university hospitals in Denmark in 2012-13 (n = 766)...
March 2018: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/29458321/differential-effects-of-isotonic-and-hypotonic-4-albumin-solution-on-intracranial-pressure-and-renal-perfusion-and-function
#5
Naoya Iguchi, Junko Kosaka, Joseph Bertolini, Clive N May, Yugeesh R Lankadeva, Rinaldo Bellomo
OBJECTIVES: Albumin is used to resuscitate trauma patients but may increase intracranial pressure (ICP). Its effects on renal blood flow and function are unknown. Our aim was to examine the effects of hypertonic albumin on ICP and renal function, and if any effects are due to the hypotonicity of the solution containing albumin or to albumin itself. DESIGN, SETTING AND SUBJECTS: Cross-over, randomised controlled experimental study of six adult Merino ewes in the animal facility of a research institute...
March 2018: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/29458320/evaluation-of-urea-and-creatinine-change-during-continuous-renal-replacement-therapy-effect-of-blood-flow-rate
#6
Nigel Fealy, Leanne Aitken, Eugene du Toit, Michael Bailey, Ian Baldwin
OBJECTIVE: To determine if faster blood flow rate (BFR) has an effect on solute maintenance in continuous renal replacement therapy. DESIGN: Prospective randomised controlled trial. SETTING: 24-bed, single centre, tertiary level intensive care unit. PARTICIPANTS: Critically ill adults requiring continuous renal replacement therapy (CRRT). INTERVENTIONS: Patients were randomised to receive one of two BFRs: 150 mL/min or 250 mL/min...
March 2018: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/29458319/proportional-assist-ventilation-versus-pressure-support-ventilation-in-weaning-ventilation-a-pilot-randomised-controlled-trial
#7
John Botha, Cameron Green, Ian Carney, Kavi Haji, Sachin Gupta, Ravindranath Tiruvoipati
OBJECTIVE: Proportional assist ventilation with load-adjustable gain factors (PAV+) is a mode of ventilation that provides assistance in proportion to patient effort. This may have physiological and clinical advantages when compared with pressure support ventilation (PSV). Our objective was to compare these two modes in patients being weaned from mechanical ventilation. DESIGN: Prospective randomised controlled trial comparing PSV with PAV+. SETTING: University-affiliated, tertiary referral intensive care unit (ICU)...
March 2018: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/29458318/protocol-summary-and-statistical-analysis-plan-for-the-intensive-care-unit-randomised-trial-comparing-two-approaches-to-oxygen-therapy-icu-rox
#8
Diane M Mackle, Michael J Bailey, Richard W Beasley, Rinaldo Bellomo, Victoria L Bennett, Adam M Deane, Glenn M Eastwood, Simon Finfer, Ross C Freebairn, Edward Litton, Natalie J Linke, Colin J McArthur, Shay P McGuinness, Rakshit Panwar, Paul J Young
BACKGROUND: The balance of risks and benefits of conservative v standard care oxygen strategies for patients who are invasively ventilated in the intensive care unit (ICU) is uncertain. OBJECTIVE: To describe the study protocol and statistical analysis plan for the ICU randomised trial comparing two approaches to oxygen therapy (ICU-ROX). DESIGN, SETTING AND PARTICIPANTS: Protocol for a multicentre, randomised, participant and outcome assessor-blinded, standard care-controlled, parallel-group, two-sided superiority trial to be conducted in up to 22 ICUs in Australia and New Zealand...
March 2018: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/29458317/statistical-analysis-plan-for-the-augmented-versus-routine-approach-to-giving-energy-trial-target
#9
(no author information available yet)
BACKGROUND: The Augmented versus Routine Approach to Giving Energy Trial (TARGET) is a 4000-patient randomised, double-blind controlled trial designed to evaluate whether enteral delivery of recommended energy goals using a 1.5 kcal/mL enteral nutrition formulation improves clinical outcomes, compared with a 1 kcal/mL enteral nutrition formulation delivered at the same goal rate, in critically ill patients receiving invasive mechanical ventilation. OBJECTIVE: In keeping with best practice, and in accordance with other trials conducted by the investigators, a pre-specified statistical analysis plan has been described and made public before completion of patient recruitment and data collection into the TARGET trial...
March 2018: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/29458316/study-protocol-for-the-augmented-versus-routine-approach-to-giving-energy-trial-target
#10
(no author information available yet)
BACKGROUND: Nutrition is routinely provided to critically ill patients who are mechanically ventilated and remain in the intensive care unit for more than a few days. Nasogastric feeding, which is standard practice for patients who are unable to tolerate oral nutrition, typically delivers less than 60% of the recommended energy requirements. It remains uncertain whether the delivery of about 100% of the recommended energy goals via the enteral route will affect survival and other important clinical outcomes...
March 2018: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/29458315/the-disconnect-between-nutrition-guidelines-and-evidence-how-much-protein-should-i-prescribe-to-this-critically-ill-patient
#11
Adam M Deane, Sandra L Peake, Marianne J Chapman
No abstract text is available yet for this article.
March 2018: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/29297629/pharmacodynamics-of-intravenous-frusemide-bolus-in-critically-ill-patients
#12
Luca Cioccari, Rinaldo Bellomo
No abstract text is available yet for this article.
December 2017: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/29202262/pharmacodynamics-of-intravenous-frusemide-bolus-in-critically-ill-patients
#13
LETTER
Frank Shann
No abstract text is available yet for this article.
December 2017: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/29202261/intensive-care-unit-randomised-trial-comparing-two-approaches-to-oxygen-therapy-icu-rox-results-of-the-pilot-phase
#14
RANDOMIZED CONTROLLED TRIAL
Paul J Young, Diane M Mackle, Michael J Bailey, Richard W Beasley, Victoria L Bennett, Adam M Deane, Glenn M Eastwood, Simon Finfer, Ross C Freebairn, Edward Litton, Natalie J Linke, Colin J McArthur, Shay P McGuinness, Rakshit Panwar, Rinaldo Bellomo
OBJECTIVE: The objective of the intensive care unit randomised trial comparing two approaches to oxygen therapy (ICU-ROX) pilot phase, which included the first 100 patients of an overall sample of 1000, was to examine feasibility. DESIGN: Investigator-initiated, prospective, parallel-group, pilot randomised controlled trial. SETTING: Six medical-surgical intensive care units (ICUs) in Australia and New Zealand, with participants recruited from September 2015 through June 2016...
December 2017: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/29202260/interobserver-agreement-for-post-mortem-renal-histopathology-and-diagnosis-of-acute-tubular-necrosis-in-critically-ill-patients
#15
MULTICENTER STUDY
Neil J Glassford, Alison Skene, Maria B Guardiola, Matthew J Chan, Sean M Bagshaw, Rinaldo Bellomo, Kim Solez
BACKGROUND: The renal histopathology of critically ill patients dying with acute kidney injury (AKI) in intensive care units of high income countries remains uncertain. METHODS: Retrospective observational assessment of interobserver agreement in the reporting of renal post mortem histopathology, and the ability of pathologists blinded to the clinical context to independently identify the presence of pre-mortem AKI from digital images of histological sections from 34 critically ill patients dying in teaching hospitals in Australia and Canada...
December 2017: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/29202259/bedside-lung-ultrasound-in-the-care-of-the-critically-ill
#16
Máté Rudas, Sam Orde, Marek Nalos
OBJECTIVE: To describe the technique and review the utility of bedside lung ultrasound in acute care. SUMMARY: Lung ultrasound is a useful point-of-care investigation in acute care, especially in patients with dyspnoea or haemodynamic instability. Although normal lung parenchyma is not accessible to ultrasound, distinctive artefacts arising from parietal and visceral pleura indirectly imply the presence of normal lung. As aeration of lung tissue reduces with disease process, visual assessment of several pathologic entities by ultrasound becomes possible...
December 2017: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/29202258/the-spice-iii-study-protocol-and-analysis-plan-a-randomised-trial-of-early-goaldirected-sedation-compared-with-standard-care-in-mechanically-ventilated-patients
#17
RANDOMIZED CONTROLLED TRIAL
Yahya Shehabi, Andrew B Forbes, Yaseen Arabi, Frances Bass, Rinaldo Bellomo, Suhaini Kadiman, Belinda D Howe, Colin McArthur, Michael C Reade, Ian Seppelt, Jukka Takala, Steve Webb, Matthew P Wise
BACKGROUND: Sedation strategy in critically ill patients who are mechanically ventilated is influenced by patient-related factors, choice of sedative agent and the intensity or depth of sedation prescribed. The impact of sedation strategy on outcome, in particular when delivered early after initiation of mechanical ventilation, is uncertain. OBJECTIVES: To present the protocol and analysis plan of a large randomised clinical trial investigating the effect of a sedation strategy, in critically ill patients who are mechanically ventilated, based on a protocol targeting light sedation using dexmedetomidine as the primary sedative, termed "early goal-directed sedation", compared with usual practice...
December 2017: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/29202257/maintenance-fluid-practices-in-paediatric-intensive-care-units-in-australia-and-new-zealand
#18
Shailesh Bihari, Ben Gelbart, Ian Seppelt, Kelly Thompson, Nicola Watts, Shivesh Prakash, Marino Festa, Andrew Bersten
BACKGROUND: Maintenance fluid administration is a common practice in paediatric intensive care units (PICUs), contributing to daily fluid intake and fluid balance, but little is known about this practice. OBJECTIVES: To determine the volume and type of maintenance fluid delivered to PICU patients, and to assess changes in practice compared with a previous time point. METHODS: A prospective, observational, single-day, point prevalence study of paediatric patients from 11 Australian and New Zealand PICUs, conducted in 2014...
December 2017: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/29202256/long-term-mortality-of-critically-ill-patients-with-diabetes-who-survive-admission-to-the-intensive-care-unit
#19
Yasmine Ali Abdelhamid, Mark P Plummer, Mark E Finnis, Vishwanath Biradar, Shailesh Bihari, Palash Kar, Stewart Moodie, Michael Horowitz, Jonathan E Shaw, Liza K Phillips, Adam M Deane
OBJECTIVE: Long-term outcomes of critically ill patients with diabetes are unknown. Our objectives were to evaluate the effect of diabetes on both long-term survival rates and the average number of years of life lost for patients admitted to an intensive care unit who survived to hospital discharge. DESIGN AND PARTICIPANTS: A data linkage study evaluating all adult patients in South Australia between 2004 and 2011 who survived hospitalisation that required admission to a public hospital ICU...
December 2017: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/29202255/patterns-of-organ-donation-in-children-in-australia-and-new-zealand
#20
Tarryn Corkery-Lavender, Johnny Millar, Elena Cavazzoni, Ben Gelbart
OBJECTIVES: Paediatric organ donation (OD) represents a small proportion of total OD in Australia and New Zealand. Our aim was to describe the patterns of paediatric OD, specifically, the demographic characteristics and donation outcomes over two time periods. DESIGN: We performed a retrospective study using national OD and intensive care registry data from intensive care units in Australia and New Zealand from 1 January 2000 to 31 December 2015. Data were analysed between two time periods...
December 2017: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
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