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Human Fertility: Journal of the British Fertility Society

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https://www.readbyqxmd.com/read/27931129/comparison-of-intracytoplasmic-sperm-injection-with-testicular-spermatozoa-success-in-infertile-men-with-obstructive-and-non-obstructive-azoospermia-a-retrospective-analysis
#1
Ibrahim Yalcin, Bulent Berker, Yavuz Emre Sukur, Korhan Kahraman, Can Ates
The aim of this study was to compare the outcome of intracytoplasmic sperm injection (ICSI) and embryo transfer between couples with infertility due to male non-obstructive azoospermia (NOA) and obstructive azoospermia (OA). A retrospective analysis of 234 couples with azoospermia who were treated by ICSI and embryo transfer between January 2007 and October 2010 was performed. There were 61 couples in NOA group and 173 couples in OA group. Fertilization rates, pregnancy and clinical pregnancy rates were the main outcome measures...
December 8, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27927044/dehydroepiandrosterone-dhea-supplementation-and-ivf-outcome-in-poor-responders
#2
Olga Triantafyllidou, George Sigalos, Nikos Vlahos
Ovarian stimulation of poor ovarian responders still remains a challenging issue. The incidence of poor responders among infertile women is reported in 9-24% IVF cycles and is associated with very low clinical pregnancy rates. Different treatments have been reported in the literature in an attempt to identify the best stimulation protocol for those patients. Administration of dehydroepiandrosterone acetate (DHEA) was suggested as a promising treatment. It is well known that androgens can influence ovarian follicular growth, augment steroidogenesis, promote follicular recruitment and increase the number of primary and pre-antral follicles...
December 7, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27900886/premature-and-multiple-births-in-ivf-are-associated-with-pretreatment-circulating-lh-hcg-receptor-concentration
#3
Anne Chambers, Craig Fairbairn, Marco Gaudoin, Walter Mills, Subhasis Banerjee
The luteinizing hormone (LH) and pregnancy hormone, human chorionic gonadotrophin (hCG), share a common receptor: LH/hCG-R or LHCGR. In this prospective study involving 290 patients undergoing in vitro fertilization (IVF) and embryo transfer, we have examined whether pretreatment circulating LHCGR (sLHCGR) influences the course of pregnancy and perinatal outcome after embryo transfer. The blood samples were collected before the fertility treatment began and sLHCGR concentrations were measured using an enzyme-linked immunosorbent assay (ELISA) test...
November 30, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27894197/temporal-validation-of-a-simplified-blastocyst-grading-system
#4
Alison Richardson, Sophie Brearley, Saran Ahitan, Sarah Chamberlain, Tracey Davey, Lyndsey Zujovic, James Hopkisson, Bruce Campbell, Nick Raine-Fenning
We have recently established the clinical effectiveness and credibility of a simplified blastocyst grading system by demonstrating its prognostic potential and the inter- and intra-observer variability associated with it. To be considered clinically useful, however, the grading system also needs to be accurate (i.e. well calibrated with good discriminative ability). This study prospectively evaluates the performance of the grading system on subsequent patients from the same IVF unit in an attempt to temporally validate the model...
November 28, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27884061/embryos-cultured-in-a-time-lapse-system-result-in-superior-treatment-outcomes-a-strict-matched-pair-analysis
#5
Amy Barrie, Roy Homburg, Garry McDowell, Jeremy Brown, Charles Kingsland, Stephen Troup
A retrospective strict matched-pair analysis of 728 treatment cycles between January 2011 and September 2014 was performed. A total of 364 treatment cycles, where all embryos were cultured and examined in EmbryoScope(®), were matched to treatment cycles where all the embryos were cultured in a standard incubator with conventional morphological examination. Matching was performed for patient age, number of oocytes collected, treatment type and date of oocyte collection (± six months). The clinical (CPR), implantation (IR), live birth (LBR) and miscarriage rates (MR) were calculated and considered significant when p < 0...
November 24, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27876427/fmr1-premutation-not-only-important-in-premature-ovarian-failure-but-also-in-diminished-ovarian-reserve
#6
Ali Eslami, Kamelia Farahmand, Mehdi Totonchi, Tahereh Madani, Ummulbanin Asadpour, Shabnam Zari Moradi, Hamid Gourabi, Anahita Mohseni-Meybodi
It is recognized that FMR1 premutation expansions are associated with premature ovarian failure (POF), but their role in diminished ovarian reserve (DOR) is not clearly established. Moreover, the impact of smaller repeats at the boundary of premutation and normal is less clear. Therefore, we have compared the frequency of these intermediate (45-54 repeats) and premutation (>55) sized FMR1 CGG repeats among a patients group including 188 DOR and 173 POF women and 200 controls. FSH and LH concentrations were also compared between intermediate and premutation ranges in patients...
November 23, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27876421/prognostic-factors-for-patients-undergoing-vitrified-warmed-human-embryo-transfer-cycles-a-retrospective-cohort-study
#7
Toshifumi Takahashi, Ayumi Hasegawa, Hideki Igarashi, Mitsuyoshi Amita, Jun Matsukawa, Isao Takehara, Satoko Suzuki, Satoru Nagase
We examined the prognostic factors for pregnancy in 210 vitrified-warmed embryo transfer (ET) cycles in 121 patients. The univariate analysis showed that age, gravida, the number of cycles associated with infertility caused by endometriosis, the number of previous assisted reproductive technology (ART) treatment cycles, and the number of ICSI procedures were significantly lower in pregnant cycles compared with non-pregnant cycles. The percentages of ET using at least one intact embryo and of ET using at least one embryo that had developed further after warming were significantly higher in pregnant cycles compared with non-pregnant cycles...
November 23, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27855570/genetics-of-suspected-thrombophilia-in-serbian-females-with-infertility-including-three-cases-homozygous-for-fii-20210a-or-fv-1691a-mutations
#8
Jelena Djurovic, Oliver Stojkovic, Jelena Todorovic, Aleksandra Brajic, Sanja Stankovic, Svetlana Obradovic, Gorana Stamenkovic
Reproductive failure (recurrent foetal loss, unexplained infertility and IVF implantation failure) may be, in a number of cases, explained by thrombophilia, either acquired or inherited. Several genes contribute to thrombophilia, some with major effect (Factor V, Factor II), and some with minor effect (MTHFR, PAI-1, ATIII, etc.). The aim of this study was to estimate frequency of thrombophilia-associated genotypes (FII20210G > A, FV1691G > A, MTHFR677C > T and PAI-1 -675 4G/5G) in a group of 1631 Serbian women experiencing reproductive failure, and compare it with a healthy, female control group...
November 18, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27852138/corrigendum
#9
(no author information available yet)
No abstract text is available yet for this article.
November 17, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27848252/feasibility-and-effects-of-a-decision-aid-about-fertility-preservation
#10
Mirjam M Garvelink, Moniek M Ter Kuile, Leoni A Louwé, Carina G J M Hilders, Anne M Stiggelbout
This paper reports on the feasibility and preliminary effects of a decision aid (DA) about female fertility preservation (FP). We conducted a pilot multicentre randomized controlled trial of women with breast cancer aged 18-40 who were randomized to brochures or the DA. Over 18 months, 62 women were eligible, of which 42 were invited by their healthcare provider (74%) to participate in the study. A total of 36 women signed up for participation and 26 (72%) were randomized to brochures (n = 13) or the DA (n = 13)...
November 16, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27846734/reproductive-technologies-and-the-risk-of-congenital-heart-defects
#11
Satoru Iwashima, Takamichi Ishikawa, Hiroaki Itoh
Assisted reproductive technology (ART) has become widespread, accounting for ∼2% of all births worldwide, with a similar proportion in Japan. Our goal was to determine whether ART is associated with an increased risk of congenital heart defect (CHD). The study subjects were 2716 pregnant women (2317 in a spontaneous conception [SC] group and 399 in an assisted conception [AC] group). Of patients in the AC group, 142 were treated with ovulation-inducing agents (OIAs), 56 with artificial insemination by the husband (AIH), 159 with in vitro fertilization (IVF), and 42 with intracytoplasmic sperm injection (ICSI)...
November 16, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27844488/how-do-laboratory-embryo-transfer-techniques-affect-ivf-outcomes-a-review-of-current-literature
#12
George Sigalos, Olga Triantafyllidou, Nikos Vlahos
Over the last few years, many studies have focused on embryo selection methods, whereas little attention has been given to the standardization of the procedure of embryo transfer. In this review, several parameters of the embryo transfer procedure are examined, such as the: (i) culture medium volume and loading technique; (ii) syringe and catheters used for embryo transfer; (iii) viscosity and composition of the embryo transfer medium; (iv) environment of embryo culture; (v) timing of embryo transfer; (vi) and standardization of the embryo transfer techniques...
November 15, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27841038/experiences-of-faith-group-members-using-new-reproductive-and-genetic-technologies-a-qualitative-interview-study
#13
Jackie Leach Scully, Sarah Banks, Robert Song, Jackie Haq
This paper explores the experiences of members of faith groups deciding whether or not to use new reproductive or genetic technologies (NRGTs). It is based on 16 in-depth, semi-structured interviews with people with direct experience of NRGTs. Participants identified as members of Christian or Muslim faith traditions and had been faced with deciding whether or not to make use of novel forms of fertility treatment or genetic testing. The findings show that members of faith groups may experience specific barriers of access, and distinctive ethical difficulties, when considering the use of different forms of NRGTs...
November 14, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27825272/cost-effectiveness-of-letrozole-and-purified-urinary-fsh-in-treating-women-with-clomiphene-citrate-resistant-polycystic-ovarian-syndrome-a-randomized-controlled-trial
#14
AbdelGany Hassan, Nesreen Shehata, Amr Wahba
We aimed to compare the cost effectiveness of letrozole versus purified urinary follicle stimulating hormone (FSH) in treating patients with clomiphene citrate (CC)-resistant polycystic ovary syndrome (PCOS). This was a randomized trial conducted in Cairo University and Beni-Suef University Hospitals, Egypt. A cohort of 140 eligible women was randomized to receive either letrozole 2.5 mg twice daily for five days, or FSH using a graduated regimen starting with a dose of 75 IU. Treatment was repeated for three months if pregnancy did not occur...
November 8, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27819492/hba-score-in-relation-to-donor-semen-profiles-and-live-birth-rates-a-preliminary-study
#15
C Michailidou-Ahmed, A A Sharpe, E V Burrell, J A Blower, N Potdar
We sought to determine whether sperm donor selection could be improved by using the hyaluronan binding assay (HBA) score to predict live birth rates (LBRs) in donor insemination treatments. Thirty donor samples were included: five fresh samples to assess whether HBA score is affected by cryopreservation and 25 frozen samples from donors whose sperm gave rise to known live births, divided into three groups, with success rates ≥50%, <50-33% and <33%, to examine whether HBA score correlates with LBRs...
November 7, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27804310/efficacy-of-concurrent-administration-of-mifepristone-and-misoprostol-for-termination-of-pregnancy
#16
Manju Lata Verma, Uma Singh, Nisha Singh, Pushpa Lata Sankhwar, Sabuhi Qureshi
In this prospective randomized parallel group study, subjects with a pregnancy of less than 63 d were randomized to receive either (i) 200 mg oral mifepristone plus 400 μg misoprostol per vaginally concurrently (group A); (ii) or the administration of misoprostol after 48 h (group B). Transvaginal sonography was performed on the 14th day of misoprostol administration to confirm complete abortion. The primary outcome was to compare the rates of complete abortion in two groups. Secondary outcomes were to compare induction abortion interval, side effects and compliance...
November 2, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27802789/follicular-fluid-lipid-peroxidation-levels-in-women-with-endometriosis-during-controlled-ovarian-hyperstimulation
#17
Camila Bruna de Lima, Fernanda Bertuccez Cordeiro, Mariana Camargo, Daniel Suslik Zylbersztejn, Agnaldo Pereira Cedenho, Ricardo Pimenta Bertolla, Edson Guimarães Lo Turco
This observational study aimed to establishing a relationship between lipid peroxidation and endometriosis in women undergoing controlled ovarian hyperstimulation. A total of 79 women were divided into two groups: (i) controls (tubal or male factor); and (ii) endometriosis (stages III/IV). The endometriosis diagnosis was confirmed by videolaparoscopy and the controlled ovarian stimulation protocol was similar to all patients. Follicular fluid (FF) lipid peroxidation levels were determined through the quantification of malondialdehyde...
November 1, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27796134/professor-henry-j-leese-honorary-member-of-the-european-society-of-human-reproduction-and-embryology
#18
Daniel R Brison
No abstract text is available yet for this article.
October 31, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27778521/gender-differences-in-perception-of-psychosocial-distress-and-coping-mechanisms-among-infertile-men-and-women-in-saudi-arabia
#19
Fahad D Alosaimi, Mujahid Bukhari, Maram Altuwirqi, Mohamad Habous, Khaled Madbouly, Zeinab Abotalib, Saleh Binsaleh
The objective of the study was to evaluate the differences in psychosocial distress and coping mechanisms among infertile men and women in Saudi Arabia (SA). We performed a cross-sectional study of infertile patients (206 women and 200 men) attending infertility clinics in three referral hospitals in Riyadh, SA. A semi-structured questionnaire was developed to assess socio-demographic, clinical and psychosocial variables. Infertility-related psychosocial pressures were reported in 79 (39.7%) male and 97 (47...
October 25, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27778517/fertility-related-knowledge-and-information-seeking-behaviour-among-people-of-reproductive-age-a-qualitative-study
#20
Karin Hammarberg, Rebecca Zosel, Caroline Comoy, Sarah Robertson, Carol Holden, Mandy Deeks, Louise Johnson
Some potentially modifiable factors adversely affect fertility and pregnancy health. To inform a fertility health promotion programme, this study investigated fertility knowledge and information-seeking behaviour among people of reproductive age. This was a qualitative study involving six focus group discussions with women and men who intended to have children in the future and eight paired interviews with couples who were actively trying to conceive. Participants (n = 74) themselves generally claimed 'low' to 'average' levels of knowledge about fertility...
October 25, 2016: Human Fertility: Journal of the British Fertility Society
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