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Human Fertility: Journal of the British Fertility Society

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https://www.readbyqxmd.com/read/28152641/a-review-of-paediatric-and-adolescent-gynaecology-services-in-a-tertiary-outpatient-clinic
#1
Mugdha Kulkarni, Julie Glanville, Sally Phillot, Adam Balen
Adolescence is a distinctive stage in human development during which many simple and complex medical conditions can present for the first time. Paediatric and adolescent gynaecological conditions need careful multidisciplinary clinical management with a sensitive approach understanding the patients' psychological and physiological circumstances. The objective of this study is to review the tertiary paediatric and adolescent gynaecology service in Leeds, United Kingdom and to present an overview of the various conditions that present to such a clinic...
February 2, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28142296/probiotic-supplementation-and-the-effects-on-weight-loss-glycaemia-and-lipid-profiles-in-women-with-polycystic-ovary-syndrome-a-randomized-double-blind-placebo-controlled-trial
#2
Shahnaz Ahmadi, Mehri Jamilian, Maryam Karamali, Maryam Tajabadi-Ebrahimi, Parvaneh Jafari, Mohsen Taghizadeh, Mohammad Reza Memarzadeh, Zatollah Asemi
The aim of the current study was to assess the effects of probiotic supplementation on weight loss, glycaemia and lipid profiles in women with polycystic ovary syndrome (PCOS). In a randomized, double-blind, placebo-controlled trial, 60 women with PCOS were randomized to receive probiotic capsule (n = 30) or placebo (n = 30) for 12 weeks. Consumption of probiotic supplements resulted in a significant reduction in weight (-0.5 ± 0.4 vs. +0.1 ± 1.0 kg, p = 0.004) and BMI (-0.2 ± 0...
February 1, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28142289/time-lapse-imaging-is-it-time-to-incorporate-this-technology-into-routine-clinical-practice
#3
Priya Bhide, Abha Maheshwari, Rachel Cutting, Susan Seenan, Anita Patel, Khalid Khan, Roy Homburg
Time-lapse imaging (TLI) systems for embryo incubation, assessment and selection are a novel technology available to in vitro fertilization (IVF) clinics. However, there is uncertainty about their clinical and cost-effectiveness and insufficient good quality evidence to warrant their routine use. Despite this, enthusiastic commercial marketing and slipping clinical equipoise have led to the widespread hasty introduction of this technology into practice, often at a considerable expense to the patient. We have reviewed the published literature and aim to summarize the strengths, weaknesses, opportunities and threats of these systems...
February 1, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28118765/lines
#4
Jacqui O'kane
I wrote this poem while marveling at the birth of my now 4-year-old daughter. My husband Stephen and I had tried to conceive for several months, and we were overjoyed when Sophie finally arrived. Embarking on the fertility journey again - this time with deeper awareness of my own subfertility - I reflect anew on the treasures and travails of pregnancy. Specifically, I have noticed that my greatest hopes hinge on the most miniscule lines of a home pregnancy test. That such small lines could subsume sublime significance is a wonder to me...
January 24, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28112003/predictors-of-twin-pregnancy-after-ovarian-stimulation-and-intrauterine-insemination-in-women-with-unexplained-infertility
#5
Arie Berkovitz, Tal Biron-Shental, Yael Pasternak, Reuven Sharony, Anat Hershko-Klement, Amir Wiser
Multi-foetal gestation is a well-known, adverse outcome of infertility treatment. Maternal and obstetrical complications are more frequent in multiple pregnancies compared to singletons. The aim of this study was to determine parameters that affect the risk for multiple pregnancies after ovarian stimulation (OS) with intrauterine insemination (IUI). We retrospectively evaluated all cases of OS with IUI cycles that ended with successful clinical pregnancy. A total of 259 pregnancies were analysed (175 singletons, 63 twins and 21 triplets)...
January 22, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28111995/the-association-of-different-auto-antibodies-against-ovarian-tissues-and-gonadotropins-and-poor-ovarian-response-in-intracytoplasmic-sperm-injection-cycles
#6
Ladan Mohammadi Yeganeh, Ashraf Moini, Mandana Hemmat, Reza Salman Yazdi, Narges Bagheri Lankarani, Shabnam Khodabakhshi, Arash Behbahanian
This study aimed to assess the possible association between ovarian auto-antibodies and poor ovarian response to controlled ovarian hyperstimulation (COH) in patients undergoing intracytoplasmic sperm injection (ICSI) cycles. In total, 42 poor responders and 43 male factor subjects were enrolled in the study and underwent either a standard long gonadotropin-releasing hormone (GnRH) agonist or antagonist protocol. Anti-ovarian, anti-oocyte, anti-zona pellucida (anti-ZP) and anti-gonadotropin antibodies in their sera and follicular fluid (FF) were measured by an enzyme-linked immunosorbent assay technique (ELISA)...
January 22, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28111993/parents-are-rapidly-getting-older-in-south-korea
#7
Kitae Sohn
While scholars and policymakers have investigated the causes and consequences of low fertility, they have neglected a related issue: advanced parental age. This is an important issue because advanced parental age adversely affects babies in the short and long run. South Korea recently topped the list of low-fertility countries, and so this study examined the trends in parental age in this country. We analysed all births between 1997 and 2014, the census for 2000 and 2010, and aggregate marriage data to report the trends in age at first marriage, interval from marriage to first birth, and parental age at first birth and at all births...
January 22, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28076980/status-of-sperm-born-oocyte-activating-factors-pawp-plc%C3%AE-and-sperm-chromatin-in-uncapacitated-capacitated-and-acrosome-reacted-conditions
#8
Marziyeh Tavalaee, Kazem Parivar, Abdol-Hossein Shahverdi, Kamran Ghaedi, Mohammad Hossein Nasr-Esfahani
The aim of this study was to investigate the value of sperm factors PAWP and PLCζ involved in oocyte activation and sperm chromatin status, as indicators of sperm quality during uncapacitated, capacitated and acrosome-reacted conditions. Semen samples collected from 10 normozoospermic men and sperm factors PAWP, PLCζ, protamine deficiency and DNA fragmentation evaluated in fresh samples, processed sample by DGC (density gradient centrifugation), capacitated and acrosome reacted sperm, using immunofluorescence and flow cytometry...
January 12, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27973924/sexual-dysfunction-in-female-patients-with-type-2-diabetes-mellitus-a-cross-sectional-single-centre-study-among-turkish-patients
#9
Ercan Tuncel, Onur Durgun, Hande Peynirci, Canan Ersoy
The aim of the study was to assess the prevalence of female sexual function and related factors in Turkish women with type 2 diabetes mellitus (T2DM). A total of 93 female patients diagnosed with T2DM (age 48.0 ± 7.2 years (Mean ± SD) were included. Data on age, diabetes age, HbA1c level, educational level, diabetes treatment, diabetes-related complications, co-morbid disorders and concomitant medications were recorded, as were the scores obtained using a Female Sexual Function Index (FSFI) questionnaire...
December 14, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27931129/comparison-of-intracytoplasmic-sperm-injection-with-testicular-spermatozoa-success-in-infertile-men-with-obstructive-and-non-obstructive-azoospermia-a-retrospective-analysis
#10
Ibrahim Yalcin, Bulent Berker, Yavuz Emre Sukur, Korhan Kahraman, Can Ates
The aim of this study was to compare the outcome of intracytoplasmic sperm injection (ICSI) and embryo transfer between couples with infertility due to male non-obstructive azoospermia (NOA) and obstructive azoospermia (OA). A retrospective analysis of 234 couples with azoospermia who were treated by ICSI and embryo transfer between January 2007 and October 2010 was performed. There were 61 couples in NOA group and 173 couples in OA group. Fertilization rates, pregnancy and clinical pregnancy rates were the main outcome measures...
December 8, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27927044/dehydroepiandrosterone-dhea-supplementation-and-ivf-outcome-in-poor-responders
#11
Olga Triantafyllidou, George Sigalos, Nikos Vlahos
Ovarian stimulation of poor ovarian responders still remains a challenging issue. The incidence of poor responders among infertile women is reported in 9-24% IVF cycles and is associated with very low clinical pregnancy rates. Different treatments have been reported in the literature in an attempt to identify the best stimulation protocol for those patients. Administration of dehydroepiandrosterone acetate (DHEA) was suggested as a promising treatment. It is well known that androgens can influence ovarian follicular growth, augment steroidogenesis, promote follicular recruitment and increase the number of primary and pre-antral follicles...
December 7, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27819492/hba-score-in-relation-to-donor-semen-profiles-and-live-birth-rates-a-preliminary-study
#12
C Michailidou-Ahmed, A A Sharpe, E V Burrell, J A Blower, N Potdar
We sought to determine whether sperm donor selection could be improved by using the hyaluronan binding assay (HBA) score to predict live birth rates (LBRs) in donor insemination treatments. Thirty donor samples were included: five fresh samples to assess whether HBA score is affected by cryopreservation and 25 frozen samples from donors whose sperm gave rise to known live births, divided into three groups, with success rates ≥50%, <50-33% and <33%, to examine whether HBA score correlates with LBRs...
December 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27796134/professor-henry-j-leese-honorary-member-of-the-european-society-of-human-reproduction-and-embryology
#13
Daniel R Brison
No abstract text is available yet for this article.
December 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27734719/artificial-oocyte-activation-after-intracytoplasmic-morphologically-selected-sperm-injection-a-prospective-randomized-sibling-oocyte-study
#14
Batu Aydinuraz, Enver Kerem Dirican, Safak Olgan, Ozlem Aksunger, Onur Kadir Erturk
This study aimed to evaluate the effect of artificial oocyte activation (AOA) by calcium ionophore after intracytoplasmic morphologically selected sperm injection (IMSI) on fertilization, cleavage rate and embryo quality. A total of 194 oocytes from 21 cycles from women with a history of low fertilization rate accompanying teratozoospermia were enrolled over a 3-month period. Mature oocytes from each patient were randomly allocated into two groups after IMSI. In the study group, half of the patients' oocytes (n = 97) were exposed to AOA, and in the control group (n = 97), AOA was not applied...
December 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27706954/sexual-functioning-and-quality-of-life-of-hong-kong-chinese-women-with-infertility-problem
#15
Sue Seen-Tsing Lo, Wai-Ming Kok
Infertility is estimated to affect 10-15% of couples in industrialized countries and many of them are under tremendous stress. Stress can lead to poor quality of life and sexual dysfunction in general, but little is known about their prevalence in infertile women. We, therefore, conducted this cross-sectional survey in two primary care subfertility clinics between August 2012 and April 2013. A total of 159 women completed two validated Chinese questionnaires: Female Sexual Function Index and core Fertility Quality of Life...
December 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27701914/fertility-knowledge-and-the-timing-of-first-childbearing-a-cross-sectional-study-in-japan
#16
Eri Maeda, Fumiaki Nakamura, Jacky Boivin, Yasuki Kobayashi, Hiroki Sugimori, Hidekazu Saito
Although fertility educational initiatives have increased in developed countries to prevent infertility and to broaden fertility choices, the relationship between knowledge and behaviour is still poorly understood. In order to investigate the association between fertility knowledge and timing of childbearing, we investigated male and female participants between 35 and 44 years of age who had children (n = 640) from an online survey conducted in Japan in 2013. The age at which participants actually gave birth to or fathered their first child was compared between those who were aware for at least a decade of age-related decline in female fertility (hereinafter, those with past fertility knowledge) and those without...
December 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27636744/weigh-and-wait-the-prospect-of-mitochondrial-gene-replacement
#17
Liang Xu, Rui Shi
Mitochondrial DNA transfer has recently received attention from physicians. The transfer techniques place genetic material from the egg nucleus of a woman with a mitochondrial DNA mutation into a healthy donated egg from which the nuclear DNA was removed. This technology intends to reconstruct a mitochondria-competent egg to produce a baby. Three approaches: (1) pronuclear transfer; (2) metaphase II spindle transfer (ST); and (3) polar body (PB) transfer, have been proposed and applied in animal models with very low levels of heteroplasmy...
December 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27636590/uncertainty-associated-with-assessing-semen-volume-are-volumetric-and-gravimetric-methods-that-different
#18
Bryan Woodward, Nicole Gossen, Jessica Meadows, Mathew Tomlinson
The World Health Organization laboratory manual for the examination of human semen suggests that an indirect measurement of semen volume by weighing (gravimetric method) is more accurate than a direct measure using a serological pipette. A series of experiments were performed to determine the level of discrepancy between the two methods using pipettes and a balance which had been calibrated to a traceable standard. The median weights of 1.0ml and 5.0ml of semen were 1.03 g (range 1.02-1.05 g) and 5.11 g (range 4...
December 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27624529/grade-of-the-inner-cell-mass-but-not-trophectoderm-predicts-live-birth-in-fresh-blastocyst-single-transfers
#19
Jessica Subira, Jo Craig, Karen Turner, Aysha Bevan, Eric Ohuma, Enda McVeigh, Tim Child, Muhammad Fatum
Debate continues over which morphological parameter is most important in selecting blastocysts for transfer. We aimed to investigate which parameter more accurately predicts the occurrence of a live birth by designing a retrospective cohort study of 1084 fresh elective single blastocyst transfers. Primary outcome was live birth rate (LBR) and secondary outcomes were implantation, clinical pregnancy and early pregnancy loss rates. Blastocyst expansion and inner cell mass (ICM), but not trophoectoderm, were associated with LBR in the definitive multivariable regression analysis...
December 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27563936/the-experience-of-infertility-treatment-the-male-perspective
#20
Shafali Talisa Arya, Bridget Dibb
Current research surrounding infertility is focused primarily on women alone, thus removing men from the fertility equation. However, alternative research has indicated that, although men also experience infertility, there is a paucity of research on men. Therefore, very little is understood about the experiences of infertility from the male perspective. This study adopted a qualitative approach in an attempt to explore the infertility experience from the perspective of men. Fifteen men who had experienced infertility were interviewed to explore their experiences...
December 2016: Human Fertility: Journal of the British Fertility Society
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