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Human Fertility: Journal of the British Fertility Society

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https://www.readbyqxmd.com/read/29383942/the-association-between-trans-fatty-acids-infertility-and-fetal-life-a-review
#1
Hande Çekici, Yasemin Akdevelioğlu
Trans fatty acids (TFAs) are thought to affect reproductive health by causing adverse effects on sperm morphology and ovum quality as a result of changing membrane lipid composition which, in turn, leads to impairment in metabolic pathways. This literature review examines the evidence for the effects of dietary TFAs on male and female infertility. Studies conducted between 2007 and 2017 on the effect of dietary TFAs on human reproductive health and fetal life have been included. They indicate that TFA intakes are inversely proportional to sperm concentration and total sperm count and exhibit a positive correlation with asthenospermia, as well as an adverse association on sperm concentration and semen quality...
January 31, 2018: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/29363381/clinical-outcomes-of-magnetic-activated-sperm-sorting-in-infertile-men-candidate-for-icsi
#2
Niloofar Ziarati, Marziyeh Tavalaee, Mehrnoosh Bahadorani, Mohammad Hossein Nasr Esfahani
Magnetic activated cell sorting (MACS) with annexin V microbeads deselected apoptotic sperm with externalized phosphatidylserine (PS) residues on their surface and decrease chance of such sperm to be inseminated. Therefore, the aim of this study was to evaluate efficiency of MACS procedure in a prospective randomized trial. Sixty-two semen samples were allocated into two groups and processed according to: (i) a combination of MACS with density gradient centrifugation (MACS-DGC) as study group (N = 29); and (ii) DGC alone as a control group (N = 33)...
January 24, 2018: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/29338469/assessing-efficacy-of-day-3-embryo-time-lapse-algorithms-retrospectively-impacts-of-dataset-type-and-confounding-factors
#3
Yanhe Liu, Katie Feenan, Vincent Chapple, Phillip Matson
This study investigated the efficacy of four published day 3 embryo time-lapse algorithms based on different types of datasets (known implantation data [KID] and single embryo transfer [SET]), and the confounding effect of female age and conventional embryo morphology. Four algorithms were retrospectively applied to three types of datasets generated at Fertility North between February 2013 and December 2014: (a) KID dataset (n = 270), (b) a subset of SET (n = 144, end-point = implantation), and (c) SET (n = 144, end-point = live birth), respectively...
January 16, 2018: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/29298394/fertility-preservation-for-medical-reasons-in-girls-and-women-british-fertility-society-policy-and-practice-guideline
#4
Ephia Yasmin, Neerujah Balachandren, Melanie C Davies, Georgina L Jones, Sheila Lane, Raj Mathur, Lisa Webber, Richard A Anderson
Fertility preservation in the female poses several challenges due to the invasive nature of the techniques available to achieve it. The guideline aims to bring together the evidence available for the measures for fertility preservation and their outcome. The guideline addresses fertility preservation for medical reasons and includes both oncological and non-oncological causes. The techniques that the guideline considers are: (i) embryo and oocyte cryopreservation; (ii) ovarian tissue cryopreservation; (iii) GnRH agonist suppression and (iv) ovarian transposition...
January 3, 2018: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/29172797/infertility-providers-and-patients-views-and-experiences-concerning-doctor-shopping-in-the-usa
#5
Robert Klitzman
Many questions arise concerning how infertility patients decide whether, how much and why or why not to consult more than one doctor and change physicians. To explore this issue, a total of 37 US in vitro fertilization (IVF) providers and patients were interviewed in-depth. Many infertility patients feel disappointed with infertility providers, especially after treatment failure, and then struggle to evaluate and weigh relative 'bedside manner' against technical skills, finances and hope, facing dilemmas of which doctor to choose, whether and how much, to 'shop around', how to do so, and whether and how much to give doctors 'second chances'...
November 26, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/29172789/morphometric-analysis-of-human-oocytes-using-time-lapse-does-it-predict-embryo-developmental-outcomes
#6
Azita Faramarzi, Mohammad Ali Khalili, Marjan Omidi
The aim of this prospective study was to evaluate the relationship between morphometric parameters of metaphase II (MII) oocytes and the morphokinetic behaviour of subsequent embryos derived by intra-cytoplasmic sperm injection (ICSI). The association between oocyte morphometry: (whole oocyte), ooplasm, width of zona pellucida (ZP) and perivitelline space (PVS) and first polar body (PB) with embryo morphokinetic variables, including time of second PB extrusion (tPB2), pronuclei appearance (tPN), pronuclei fading (tPNf), formation of two to eight cells (t2 to t8) and irregular cleavage events [uneven at two cells stage, cell fusion (Fu) and trichomonas mitoses (TM)] were assessed...
November 24, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28423955/double-ovarian-stimulation-duostim-protocol-for-fertility-preservation-in-female-oncology-patients
#7
Nikolaos Tsampras, Della Gould, Cheryl T Fitzgerald
This article describes a revised ovarian stimulation protocol (DuoStim) for fertility preservation in female oncology patients which aims to maximise the number of gametes obtained with subsequent improvement in cumulative birth rate, without delaying cancer treatment. Ten patients diagnosed with malignancy between September 2014 and October 2015 were included. The patients were treated with the DuoStim protocol, undergoing two consecutive ovarian stimulation cycles and two oocyte retrievals. The primary outcome was the number of oocytes collected and vitrified during each oocyte retrieval and in total...
December 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/29091012/conflicts-of-interest-in-australia-s-ivf-industry-an-empirical-analysis-and-call-for-action
#8
Brette Blakely, Jane Williams, Christopher Mayes, Ian Kerridge, Wendy Lipworth
In Australia, the growing assisted reproductive technologies (ART) industry has recently received some public criticism. Much of this criticism centres on the concern that doctors are increasingly motivated by profit, rather than patient interests. These concerns appear to suggest that the growing business of ART generates conflicts of interest (COI) for clinicians. While media reports may be rhetorically compelling, claims that ART practice is distorted by COI must be supported by empirical evidence. This preliminary study sought to engage with people involved with the ART industry and map out their concerns related to COI in ART...
November 1, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/29057680/the-association-of-renin-angiotensinogen-system-genes-polymorphisms-and-idiopathic-recurrent-pregnancy-loss
#9
Mohammad Mehdi Heidari, Mozhgan Sheikholeslami, Mahdieh Yavari, Mehri Khatami, Seyed Mohammad Seyedhassani
The most common complication of pregnancy is idiopathic recurrent pregnancy loss (RPL). To identify the contribution of gene polymorphisms to this condition, we evaluated the association between RPL and the angiotensinogen (AGT), angiotensin receptor 1 (AGTR1) and Angiotensinogen converting enzyme (ACE). In this case-control study, the frequency of AGT (rs4762 and rs699), AGTR1 (rs5186) and ACE insertion/deletion (rs4340) polymorphisms in 202 idiopathic RPL women was compared with 210 women with no history of abortion, using tetra-primer ARMS-PCR...
October 23, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28975815/office-hysteroscopic-guided-selective-tubal-chromopertubation-acceptability-feasibility-and-diagnostic-accuracy-of-this-new-diagnostic-non-invasive-technique-in-infertile-women
#10
Gaspare Carta, Patrizia Palermo, Chiara Pasquale, Valeria Conte, Ruggero Pulcinella, Stefano Necozione, Vincenza Cofini, Felice Patacchiola
The aim of this study was to evaluate accuracy, tolerability and side effects of office hysteroscopic-guided chromoperturbations in infertile women without anaesthesia. Forty-nine infertile women underwent the procedure to evaluate tubal patency and the uterine cavity. Women with unilateral or bilateral tubal stenosis at hysteroscopy with chromoperturbation, and women with bilateral tubal patency who did not conceive during the period of six months, underwent laparoscopy with chromoperturbation. The results obtained from hysteroscopy and laparoscopy in the assessment of tubal patency were compared...
October 4, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28974117/association-of-c3953t-transition-in-interleukin-1%C3%AE-gene-with-idiopathic-male-infertility-in-an-iranian-population
#11
Tayyebeh Zamani-Badi, Mohammad Karimian, Abolfazl Azami-Tameh, Hossein Nikzad
In this study we investigate the association of C3953T transition single nucleotide polymorphism in the fifth exon of the interleukin 1β gene with idiopathic male infertility. In a case-control study, blood samples were collected from 230 fertile and 207 infertile men who referred to the Kashan IVF centre. Genotypes of samples at the C3953T location were determined by polymerase chain reaction-restriction fragment length polymorphism. The data showed a significant association of TT genotype (OR = 2.49, 95%CI = 1...
October 3, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28969458/sitting-on-the-editorial-fence
#12
Allan A Pacey
No abstract text is available yet for this article.
October 2, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28969455/the-impact-of-cigarette-smoking-on-protamines-1-and-2-transcripts-in-human-spermatozoa
#13
Mohammed Hamad, Nyaz Shelko, Mathias Montenarh, Mohammed Eid Hammadeh
This study was conducted to evaluate the relation between cigarette smoking, semen quality and ratios of protamine mRNAs in smokers and non-smokers. Spermatozoa from 123 men and 64 smokers and 59 non-smokers whose female partners attended an assisted reproduction and andrology laboratory were evaluated. Protamine mRNA was extracted from purified sperm, reverse-transcribed and subjected to real-time quantitative PCR using specific primer pairs for protamine 1 (PRM1) and protamine 2 (PRM2). The main outcomes showed that PRM1 mRNA levels in smokers were significantly lower (p = 0...
October 2, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28960100/corrected-cholesterol-a-novel-marker-for-predicting-semen-post-thaw-quality-a-pilot-study
#14
Chey G Dearing, Kevin S Lindsay
Semen cryopreservation is the recommended method for protecting the fertility of men before they undergo iatrogenic treatments. However, post-thaw sperm quality is highly variable between and within individuals. Thus, prediction of post-thaw quality has not been achieved with great certainty. Men (n = 101) attending our andrology clinic each produced a single ejaculate for semen analysis and semen cryopreservation. Post-thaw semen quality was examined for associations with traditional and novel semen and seminal plasma parameters...
September 29, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28934899/knowledge-about-and-attitude-towards-fertility-preservation-in-young-female-cancer-patients-a-cross-sectional-online-survey
#15
Corinne Urech, Verena Ehrbar, Jacky Boivin, Madleina Müller, Judith Alder, Rosanna Zanetti Dällenbach, Christoph Rochlitz, Sibil Tschudin
Recent advances in cancer therapy have resulted in an increased number of long-term cancer survivors. However, because of their treatment, women might be confronted with impaired fertility. The options of fertility preservation (FP) techniques are increasing. The goal of this study was to assess knowledge about, and attitudes towards, fertility preservation in young female cancer patients. A cross-sectional online survey was conducted including 155 former female cancer patients from English and German speaking countries...
September 22, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28881151/jean-marian-purdy-remembered-the-hidden-life-of-an-ivf-pioneer
#16
Roger Gosden
Jean Purdy is almost forgotten as one of the British trio that introduced clinical IVF to the world. An unlikely pioneer, she qualified as a nurse but through indefatigable effort and unstinting loyalty to a programme that faced vitriolic opposition she became the clinical embryologist for the first IVF baby. In 1980, she helped to launch fertility services as the 'Technical Director' of Bourn Hall Clinic, near Cambridge. Although Robert Edwards and Patrick Steptoe generously credited her role in research and clinical care, a premature death in 1985 at age 39 robbed her of the reward of witnessing the blossoming of assisted reproductive technologies for patients around the world...
September 7, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28635413/the-high-responder-a-review-of-pathophysiology-and-outcomes-during-ivf-treatment
#17
Mariano Mascarenhas, Adam H Balen
This review attempts to summarize the known literature on high responders to ovarian stimulation during assisted reproductive techniques (ART). Response to gonadotrophins is subject to significant interindividual and intercycle variation, thus carrying a risk of high response or poor response to ovarian stimulation regimens. The main risk for high responders is the development of ovarian hyperstimulation syndrome (OHSS) which is associated with significant morbidity. Hence, the definition of high responders in the literature has primarily focussed on risk factors for OHSS...
September 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28814113/intracytoplasmic-sperm-injection-using-hyaluronic-acid-or-polyvinylpyrrolidone-a-time-lapse-sibling-oocyte-study
#18
Yanhe Liu, Katie Feenan, Vincent Chapple, Peter Roberts, Phillip Matson
This study evaluated the effect of sperm selection and intracytoplasmic sperm injection (ICSI) on subsequent fertilization and embryo development using the hyaluronic acid-based SpermSlow™ (HA-ICSI) compared to injection with polyvinylpyrrolidone (PVP-ICSI). A total of 206 metaphase II oocytes were collected from 21 prospectively enrolled ICSI cycles at Fertility North between July 2014 and March 2015. Sibling oocytes were randomized into HA-ICSI and PVP-ICSI (n = 103 per group). Subsequent fertilization outcomes and embryo development in terms of qualitative and quantitative time-lapse measures following three-day culture in the Embryoscope™ were compared...
August 17, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28758506/exposure-to-modern-widespread-environmental-endocrine-disrupting-chemicals-and-their-effect-on-the-reproductive-potential-of-women-an-overview-of-current-epidemiological-evidence
#19
Anetta Karwacka, Dorota Zamkowska, Michał Radwan, Joanna Jurewicz
Growing evidence indicates that exposure to widespread, environmental contaminants called endocrine disruptors (EDCs) negatively affects animal and human reproductive health and has been linked to several diseases including infertility. This review aims to evaluate the impact of environmental exposure to endocrine disrupting chemicals [phthalates, parabens, triclosan, bisphenol A (BPA), organochlorine (PCBs) and perfluorinated (PFCs) compounds] on the reproductive potential among women, by reviewing most recently published literature...
July 31, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28743202/is-fertility-associated-with-the-number-of-siblings-of-the-couple-evidence-from-india
#20
Manas Ranjan Pradhan, Jitendra Gouda
The influence of family on an individual's fertility has long been an important topic of interest in fertility research. Although studies conducted mostly in developed countries found a significant bearing of fertility of the parents on the fertility of the children, there is a lack of formal research around this topic in India. The present study analyses the effect of sibling size of husband and wife on the completed family size of women using information of 5506 ever-married women aged 45-49 years incorporated in the India Human Development Survey-II (2011-2012)...
July 26, 2017: Human Fertility: Journal of the British Fertility Society
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