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Human Fertility: Journal of the British Fertility Society

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https://www.readbyqxmd.com/read/30058411/fertility-facts-figures-and-future-plans-an-online-survey-of-university-students
#1
Eugenie Prior, Raelia Lew, Karin Hammarberg, Louise Johnson
Most people want and expect to have children but lack of awareness about the biological limits of fertility may reduce their chance of achieving their parenthood goals. We surveyed Australian university students' intentions and expectations for future parenthood, knowledge about fertility and preferred sources of fertility information. Male and female students (n = 1215) completed an anonymous 34-item online questionnaire. Fewer than 10% did not want children. Of those who wanted children, most (75%) wanted two or more...
July 30, 2018: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/29989473/fertility-related-knowledge-and-perceptions-of-fertility-education-among-adolescents-and-emerging-adults-a-qualitative-study
#2
Jacky Boivin, Amea Sandhu, Kate Brian, China Harrison
Research shows that young people do not know much about their fertility. In the present study, we examined fertility knowledge and perceptions of a fertility educational brochure (i.e. 'A Guide to Fertility') in five focus groups with adolescents (16-18 years, n = 19) and emerging adults (21-24 years, n = 14) who were childless, not currently pregnant (or for men partner not pregnant) or trying to conceive but intending to have a child in the future. Participants (n = 33) reported having poor knowledge of a range of fertility topics and feelings of surprise, fear and concern in response to the brochure, despite perceiving benefits of the provision of fertility education and feasibility of 'A Guide to Fertility'...
July 10, 2018: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/29950120/polycyclic-aromatic-hydrocarbons-exposure-and-early-miscarriage-in-women-undergoing-in-vitro-fertilization-embryo-transfer
#3
Pei Li, Rui Hua, Keyang Li, Shengtao Ma, Biao Wu, Song Quan, Zhiqiang Yu
Various factors have been reported to be associated with early miscarriages, including microbial infection, chemical toxicity, maternal disorders and genetic abnormalities. In the present study, a prospective cohort study was conducted to investigate whether urinary concentrations of hydroxylated polycyclic aromatic hydrocarbons (OH-PAHs) were associated with early pregnancy loss in women undergoing in vitro fertilization-embryo transfer (IVF-ET). Risk of spontaneous pregnancy loss in patients exposed to PAHs was analysed using 40 patients who had experienced early pregnancy loss compared to 40 who had normal live births...
June 28, 2018: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/29793356/ongoing-pregnancies-in-patients-with-unexplained-recurrent-pregnancy-loss-adverse-obstetric-outcomes
#4
Mauro Cozzolino, Francesca Rizzello, Chiara Riviello, Chiara Romanelli, Maria Coccia Elisabetta
To investigate the incidence of adverse pregnancy outcomes in couples with an unexplained Recurrent Pregnancy Loss (RPL) history, a retrospective cohort study was conducted between 2014 and 2015. The study group (A) included couples with an unexplained RPL, and the control group (B) was composed of couples who attended the Low-Risk Antenatal Unit during the same period. On the other hand, 53 couples were included in the study group (A) and on the other hand, 65 in the control group (B). Women with previous unexplained recurrent pregnancies loss had a significantly increased risk of gestational diabetes with 12 cases (22...
May 25, 2018: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/29781316/fas-and-fasl-genetic-polymorphisms-in-women-with-recurrent-pregnancy-loss-a-case-control-study
#5
Ae Ra Han, Young Min Choi, Min A Hong, Jin Ju Kim, Sung Ki Lee, Kwang Moon Yang, Eun Chan Paik, Hyeon Jeong Jeong, Jong Kwan Jun
Aberrant apoptosis at the trophoblast-maternal interface and abnormal expression of Fas and Fas ligand (FasL) have been reported in complicated pregnancies with recurrent pregnancy losses (RPL) and preeclampsia. We assessed the prevalence of Fas and FasL genetic polymorphisms in Korean women with RPL and in fertile controls. In total, 306 women with RPL and 298 fertile controls were enrolled. Genotype distributions of Fas and FasL in RPL patients versus fertile controls were examined under the Hardy-Weinberg equilibrium...
May 20, 2018: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/30024332/2017-impact-factor
#6
Allan A Pacey
No abstract text is available yet for this article.
September 2018: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28658993/influence-of-val16ala-sod2-polymorphism-on-sperm-quality-parameters
#7
Felipe Costa, Fernanda Barbisan, Charles Elias Assmann, Andressa Duarte Seehaber, Moisés Henrique Mastella Thiago Duarte, Marta Maria Medeiros Frescura Duarte, Ivana Beatrice Mânica da Cruz
The purpose of this study was to investigate the association between the Val16Ala superoxide dismutase manganese-dependent (SOD2) single nucleotide polymorphism (SNP) and sperm reproductive parameters in a sample of Brazilian men. A potential association between this polymorphism and some oxidative biochemical parameters as well as sperm plasma cell-free DNA (cfDNA) levels were also evaluated. The study was performed using semen samples obtained from male patients that had undergone semen analysis according to the 2010 World Health Organisation (WHO) recommendations and the Val16Ala-SOD2 SNP was genotyped by polymerase chain reaction (PCR)...
September 2018: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28589740/a-survey-of-scientists-awareness-of-and-attitudes-to-the-use-of-human-blood-products-and-alternatives-in-human-assisted-reproductive-technology
#8
Kelli Peirce, Peter Roberts, Jaffar Ali, Jacqui Coombes, Phillip Matson
Scientists working in assisted reproduction [members of Scientists in Reproductive Technology (SIRT) Australia, and subscribers of the online forums EmbryoMail and Quartec] were invited to complete an online questionnaire on the use of human blood products in assisted reproductive technologies (ART). A total of 260 started the questionnaire, with 208 (80%) completing it. A total of 62% of respondents had worked in human ART ≥8 years and 68% had post-graduate qualifications. The majority (82%) reported using products of animal or human origin, with 75% knowing why protein was added to culture media and 41% not worried by this...
September 2018: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28549399/a-systematic-review-investigating-psychosocial-aspects-of-egg-sharing-in-the-united-kingdom-and-their-potential-effects-on-egg-donation-numbers
#9
Timothy Bracewell-Milnes, Srdjan Saso, Hossam Abdalla, Meen-Yau Thum
This review aims to provide an up-to-date knowledge of the psychosocial aspects of egg donation from the perspectives of the egg share donor and their recipient. It explores the motives, experiences and attitudes of egg sharers and their views towards donor anonymity and disclosure. Conclusions are made on how these findings can guide clinical practice and improve egg sharing numbers. A systematic search of peer-reviewed journals of four computerized databases was undertaken. Eleven studies were included in the review...
September 2018: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28545306/developmental-potential-of-embryos-from-cycles-containing-oocytes-with-severe-ovoid-zona-pellucida
#10
Shun Xiong, Wei Han, Weiwei Liu, Lihong Wu, Jun Xia Liu, Yang Gao, Guoning Huang
The purpose of this study was to determine the incidence of oocytes with severe ovoid zona pellucida (ZP), investigate the development potential of their sibling oocytes and the clinical outcomes from affected cycles. The data were collected from our medical records. Cycles having at least one oocyte with severe ovoid ZP were defined as the 'severe ovoid group', cycles having at least one oocyte with mild ovoid ZP were defined as the 'mild ovoid group', whereas cycles without oocytes with ovoid ZPs were defined as the 'control group' (n = 150 for each group)...
September 2018: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28523980/diverse-endometrial-mrna-signatures-during-the-window-of-implantation-in-patients-with-repeated-implantation-failure
#11
Cheng Shi, Hong Jing Han, Li Juan Fan, Jing Guan, Xing Bang Zheng, Xi Chen, Rong Liang, Xiao Wei Zhang, Kun Kun Sun, Qing Hua Cui, Huan Shen
High endometrial receptivity in the window of implantation (WOI) is essential for successful implantation. However, a diagnostic tool with high specificity for impaired endometrial receptivity remains to be developed. We collected endometrium specimens during the WOI from patients with RIF and women who conceived after one IVF/ICSI attempt. We conducted mRNA microarray on the samples followed by relevant comparative and functional analysis. Microarray analysis revealed 357 dysregulated mRNAs between the two groups...
September 2018: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28521566/quality-of-life-in-turkish-infertile-couples-and-related-factors
#12
Asli Goker, Emre Yanikkerem, Ozer Birge, Naci Kemal Kuscu
Infertility is a major life crisis affecting couples' psychosocial and physical health. We aimed to assess the quality of life in Turkish infertile couples. This cross-sectional survey was carried out in 127 infertile couples admitted to a University Hospital. The quality of life was measured using the fertility quality of life tool (FertiQoL) scale. Women had lower overall quality of life than men. Women and men who were married for fewer than 10 years had a significantly lower emotional score. Women who had a history of infertility treatment, men who have lived in the town or village men with primary infertility and men who have had primary education or lower, had lower scores for mind/body subscale...
September 2018: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28438071/time-to-re-evaluate-art-protocols-in-the-light-of-advances-in-knowledge-about-methylation-and-epigenetics-an-opinion-paper
#13
Yves Menezo, Brian Dale, Kay Elder
DNA methylation is a biochemical process that modifies gene expression without changing the underlying DNA sequence, and this represents the molecular basis for imprinting and epigenetics. Recent reports have revealed alterations in DNA methylation profiles in the placenta of babies born from assisted reproductive technologies (ART). This supports several previous observations that suggested an increase in the prevalence of imprinting diseases following ART treatment, and also fits our observations regarding the metabolism and requirements of early human embryos...
September 2018: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/29683395/ivf-s-40th-birthday
#14
Allan A Pacey
No abstract text is available yet for this article.
June 2018: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28975815/office-hysteroscopic-guided-selective-tubal-chromopertubation-acceptability-feasibility-and-diagnostic-accuracy-of-this-new-diagnostic-non-invasive-technique-in-infertile-women
#15
Gaspare Carta, Patrizia Palermo, Chiara Pasquale, Valeria Conte, Ruggero Pulcinella, Stefano Necozione, Vincenza Cofini, Felice Patacchiola
The aim of this study was to evaluate accuracy, tolerability and side effects of office hysteroscopic-guided chromoperturbations in infertile women without anaesthesia. Forty-nine infertile women underwent the procedure to evaluate tubal patency and the uterine cavity. Women with unilateral or bilateral tubal stenosis at hysteroscopy with chromoperturbation, and women with bilateral tubal patency who did not conceive during the period of six months, underwent laparoscopy with chromoperturbation. The results obtained from hysteroscopy and laparoscopy in the assessment of tubal patency were compared...
June 2018: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28881151/jean-marian-purdy-remembered-the-hidden-life-of-an-ivf-pioneer
#16
Roger Gosden
Jean Purdy is almost forgotten as one of the British trio that introduced clinical IVF to the world. An unlikely pioneer, she qualified as a nurse but through indefatigable effort and unstinting loyalty to a programme that faced vitriolic opposition she became the clinical embryologist for the first IVF baby. In 1980, she helped to launch fertility services as the 'Technical Director' of Bourn Hall Clinic, near Cambridge. Although Robert Edwards and Patrick Steptoe generously credited her role in research and clinical care, a premature death in 1985 at age 39 robbed her of the reward of witnessing the blossoming of assisted reproductive technologies for patients around the world...
June 2018: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28602104/reproductive-outcome-following-pre-implantation-genetic-diagnosis-pgd-in-the-uk
#17
Abigail Sharpe, Peter Avery, Meenakshi Choudhary
In 2013, the National Health Service Commissioning board centralized the funding in England for up to three cycles of pre-implantation genetic diagnosis (PGD) for couples who have, or are carriers of, a specific genetic disorder. This study presents the historical data of PGD cycles and their clinical outcomes in UK as extrapolated from the national data registry. Retrospective analysis of outcome of cycles undergoing pre-implantation genetic diagnosis in the UK over the past 20 years was performed from the Human Fertilisation and Embryology Authority database (n = 2974)...
June 2018: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28554223/outpatient-management-of-severe-ovarian-hyperstimulation-syndrome-a-systematic-review-and-a-review-of-existing-guidelines
#18
Amr Gebril, Haitham Hamoda, Raj Mathur
Ovarian hyperstimulation syndrome (OHSS) is a potentially serious complication of assisted reproductive treatment. Management of women with severe OHSS has traditionally included hospitalisation for close monitoring and supportive treatment. The aim of this review is to assess the evidence for safety and efficacy of outpatient management of severe OHSS. A systematic review of studies describing outpatient management options was performed. Current guidance from advisory bodies was also reviewed. Outpatient management has been found in observational studies to be safe and cost-effective compared to inpatient management...
June 2018: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28523952/is-male-factor-infertility-associated-with-midlife-low-grade-inflammation-a-population-based-study
#19
Katia Keglberg Hærvig, Lene Kierkegaard, Rikke Lund, Helle Bruunsgaard, Merete Osler, Lone Schmidt
Male factor infertility is associated with an increased risk of disease and mortality, which has been related to markers of chronic systemic inflammation. The objective of this study was to investigate the association between male factor infertility and low-grade inflammation and furthermore to examine the lifetime prevalence of male factor infertility and overall infertility (also including female and couple infertility). The study population consisted of 2140 members of the Metropolit 1953 Danish Male Birth Cohort who had participated in the Copenhagen Aging and Midlife Biobank data collection in 2009-2011...
June 2018: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28521575/high-frequency-of-de-novo-daz-microdeletion-in-sperm-nuclei-of-subfertile-men-possible-involvement-of-genome-instability-in-idiopathic-male-infertility
#20
Hossein Mozdarani, Pegah Ghoraeian, Sohail Mozdarani, Parvin Fallahi, Anahita Mohseni-Meybodi
The occurrence and diagnosis of Y-chromosome microdeletions, specifically deletions of the DAZ (Deleted in Azoospermia) genes are an important issue in male infertility. Screening Y chromosome microdeletion is mainly done using polymerase chain reaction (PCR) on blood leukocytes. However, there is some evidence indicating that presence of DAZ in somatic cells might not be indicative of its presence in the germ cell lineage. Therefore, a total of 130 men with poor semen quality were examined for presence of DAZ microdeletion in their leukocytes...
June 2018: Human Fertility: Journal of the British Fertility Society
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