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European Journal of Heart Failure

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https://www.readbyqxmd.com/read/30549171/defining-a-frequent-admitter-phenotype-among-patients-with-repeat-heart-failure-admissions
#1
Yun Yun Go, Reinhard Sellmair, John C Allen, Anders Sahlén, Heerajnarain Bulluck, David Sim, Fazlur R Jaufeerally, Michael R MacDonald, Zhan Yun Lim, Ping Chai, Seet Yoong Loh, Jonathan Yap, Carolyn S P Lam
AIMS: We aimed to identify a 'frequent admitter' phenotype among patients admitted for acute decompensated heart failure (HF). METHODS AND RESULTS: We studied 10 363 patients in a population-based prospective HF registry (2008-2012), segregated into clusters based on their 3-year HF readmission frequency trajectories. Using receiver-operating characteristic analysis, we identified the index year readmission frequency threshold that most accurately predicts HF admission frequency clusters...
December 13, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/30549159/left-ventricular-reverse-remodelling-predicts-long-term-outcomes-in-patients-with-functional-mitral-regurgitation-undergoing-mitraclip-therapy-results-from-a-multicentre-registry
#2
Marianna Adamo, Cosmo Godino, Cristina Giannini, Andrea Scotti, Riccardo Liga, Salvatore Curello, Claudia Fiorina, Ermanna Chiari, Giuliano Chizzola, Alessandro Abbenante, Emanuele Visco, Luca Branca, Francesca Fiorelli, Eustachio Agricola, Stefano Stella, Carlo Lombardi, Antonio Colombo, Anna Sonia Petronio, Marco Metra, Federica Ettori
AIMS: To explore whether left ventricular reverse remodelling (LVRR) is a predictor of outcomes in patients with functional mitral regurgitation (FMR) undergoing MitraClip procedure. METHODS AND RESULTS: We analysed 184 consecutive patients with FMR who underwent successful MitraClip procedure. LVRR was defined as a reduction in left ventricular end-systolic volume ≥ 10% from baseline to 6 months. LVRR was observed in 79 (42.9%) patients. Compared with non-LVRR, LVRR patients were more likely to be females, less likely to have an ischaemic aetiology of mitral regurgitation or a prior (<6 months) heart failure (HF) hospitalization, and had smaller left ventricular dimensions...
December 13, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/30548129/predicting-one-year-mortality-in-heart-failure-using-the-surprise-question-a-prospective-pilot-study
#3
Sam Straw, Rowenna Byrom, John Gierula, Maria F Paton, Aaron Koshy, Richard Cubbon, Michael Drozd, Mark Kearney, Klaus K Witte
BACKGROUND: The Surprise Question: 'would you be surprised if this patient were to die within the next year?' has been shown to predict mortality in patients with chronic kidney disease and cancer. This prospective study aimed to determine whether the Surprise Question could identify heart failure patients with a prognosis of less than 1 year, and whether the Surprise Question can be used by different healthcare professionals. METHODS AND RESULTS: Overall, 129 consecutive patients admitted with decompensated heart failure were included...
December 11, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/30548089/impact-of-diabetes-and-sex-in-heart-failure-with-reduced-ejection-fraction-patients-from-the-asian-hf-registry
#4
Chanchal Chandramouli, Tiew-Hwa Katherine Teng, Wan Ting Tay, Jonathan Yap, Michael R MacDonald, Jasper Tromp, Limin Yan, Bambang Siswanto, Eugenio B Reyes, Tachapong Ngarmukos, Cheuk-Man Yu, Chung-Lieh Hung, Inder Anand, A Mark Richards, Lieng Hsi Ling, Judith G Regensteiner, Carolyn S P Lam
AIMS: To examine sex differences in clinical characteristics, echocardiographic features, quality of life and 1-year death or heart failure (HF) hospitalization outcomes in patients with/without diabetes mellitus (DM). METHODS AND RESULTS: Utilizing the Asian Sudden Cardiac Death in HF (ASIAN-HF) registry, 5255 patients (mean age 59.6 ± 13.1, 78% men) with symptomatic HF with reduced ejection fraction (HFrEF) were stratified by DM status to address the research aims...
December 10, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/30537261/the-prognostic-value-of-troponin-t-and-n-terminal-pro-b-type-natriuretic-peptide-alone-and-in-combination-in-heart-failure-patients-with-and-without-diabetes
#5
Rasmus Rørth, Pardeep S Jhund, Søren L Kristensen, Akshay S Desai, Lars Køber, Jean L Rouleau, Scott D Solomon, Karl Swedberg, Michael R Zile, Milton Packer, John J V McMurray
AIMS: We examined the prognostic importance of N-terminal pro B-type natriuretic peptide (NT-proBNP) and troponin T (TnT) in heart failure patients with and without diabetes. METHODS AND RESULTS: We measured NT-proBNP and TnT in the biomarker substudy of the Prospective Comparison of ARNI With ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure trial (PARADIGM-HF). Of 1907 patients, 759 (40%) had diabetes. Median TnT in patients with diabetes was 18 (interquartile range 11-27) ng/L and 13 (9-21) ng/L in those without (P < 0...
December 10, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/30537243/can-advanced-analytics-fix-modern-medicine-s-problem-of-uncertainty-imprecision-and-inaccuracy
#6
EDITORIAL
Tariq Ahmad, James V Freeman, Folkert W Asselbergs
No abstract text is available yet for this article.
December 10, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/30537163/medication-dosing-for-heart-failure-with-reduced-ejection-fraction-opportunities-and-challenges
#7
REVIEW
Catherine N Marti, Gregg C Fonarow, Stefan D Anker, Clyde Yancy, Muthiah Vaduganathan, Stephen J Greene, Ali Ahmed, James L Januzzi, Mihai Gheorghiade, Gerasimos Filippatos, Javed Butler
Multiple drug classes have shown incremental benefits in heart failure with reduced ejection fraction. Most of these trials were designed to achieve specific doses of the investigational agent. Clinical practice guidelines recommend using the same target dosing of therapies, as tolerated. However, with the increasing number of available therapies, clinicians face the challenge of simultaneously using several drugs, achieving target doses, and managing side effects that are often overlapping. Blood pressure, renal function, hyperkalaemia, and other factors may impede achieving target doses of all medications, leaving clinicians with dilemmas as to how to sequence and dose these various classes of drugs...
December 10, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/30536678/heart-failure-with-reduced-ejection-fraction-comparison-of-patient-characteristics-and-clinical-outcomes-within-asia-and-between-asia-europe-and-the-americas
#8
Pooja Dewan, Pardeep S Jhund, Li Shen, Mark C Petrie, William T Abraham, M Atif Ali, Chen-Huan Chen, Akshay S Desai, Kenneth Dickstein, Jun Huang, Songsak Kiatchoosakun, Kee-Sik Kim, Lars Køber, Wen-Ter Lai, Yuhua Liao, Ulrik M Mogensen, Byung-Hee Oh, Milton Packer, Jean L Rouleau, Victor Shi, Antonio S Sibulo, Scott D Solomon, Piyamitr Sritara, Karl Swedberg, Hiroyuki Tsutsui, Michael R Zile, John J V McMurray
AIMS: Nearly 60% of the world's population lives in Asia but little is known about the characteristics and outcomes of Asian patients with heart failure with reduced ejection fraction (HFrEF) compared to other areas of the world. METHODS AND RESULTS: We pooled two, large, global trials, with similar design, in 13 174 patients with HFrEF (patient distribution: China 833, India 1390, Japan 209, Korea 223, Philippines 223, Taiwan 199 and Thailand 95, Western Europe 3521, Eastern Europe 4758, North America 613, and Latin America 1110)...
December 10, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/30520546/idarucizumab-for-the-reversal-of-dabigatran-in-patients-undergoing-heart-transplantation
#9
LETTER
Jan M Van Keer, Thomas Vanassche, Walter Droogne, Steffen Rex, Filip Rega, Johan Van Cleemput, Peter Verhamme
No abstract text is available yet for this article.
December 6, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/30520545/effects-of-sacubitril-valsartan-on-neprilysin-targets-and-the-metabolism-of-natriuretic-peptides-in-chronic-heart-failure-a-mechanistic-clinical-study
#10
Hélène Nougué, Théo Pezel, François Picard, Malha Sadoune, Mattia Arrigo, Florence Beauvais, Jean-Marie Launay, Alain Cohen-Solal, Nicolas Vodovar, Damien Logeart
AIM: This study aimed at evaluating the effects of sacubitril/valsartan on neprilysin (NEP), and the metabolism of natriuretic peptides in heart failure (HF) and providing additional mechanistic information on the mode of action of the drug. METHODS AND RESULTS: We enrolled 73 chronic HF patients who were switched from angiotensin-converting enzyme inhibitor or angiotensin receptor blocker to sacubitril/valsartan. In addition to clinical and echocardiographic assessment, plasma biomarkers were measured at baseline, day 30 and day 90 after initiation of treatment...
December 6, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/30520544/prognostic-value-of-multiple-repeated-biomarkers-in-pulmonary-arterial-hypertension-associated-with-congenital-heart-disease
#11
LETTER
Alexandra C van Dissel, Ilja M Blok, Aeilko H Zwinderman, Arie P J van Dijk, Anthonie L Duijnhouwer, Robbert J de Winter, Barbara J M Mulder, Berto J Bouma
No abstract text is available yet for this article.
December 6, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/30520538/near-home-heart-failure-care
#12
EDITORIAL
Amy Groenewegen, Frans H Rutten
No abstract text is available yet for this article.
December 6, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/30520536/relation-between-post-myocardial-infarct-remodelling-and-gelatinase-activity-in-patients-enrolled-in-the-tiptop-trial
#13
LETTER
Giampaolo Cerisano, Piergiovanni Buonamici, Angela Migliorini, Alberto Santini, Rossella Marcucci, Anna Maria Gori, Matteo Becatti, Chiara Zocchi, Martina Berteotti, Renato Valenti
No abstract text is available yet for this article.
December 6, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/30508266/evolving-disruption-in-left-ventricular-assist-systems-forgiving-but-not-yet-forgettable
#14
EDITORIAL
Mandeep R Mehra
No abstract text is available yet for this article.
December 3, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/30485612/effectiveness-of-the-european-society-of-cardiology-heart-failure-association-website-heartfailurematters-org-and-an-e-health-adjusted-care-pathway-in-patients-with-stable-heart-failure-results-of-the-e-vita-hf-randomized-controlled-trial
#15
Kim P Wagenaar, Berna D L Broekhuizen, Tiny Jaarsma, Ilse Kok, Arend Mosterd, Frank F Willems, Gerard C M Linssen, Willem R P Agema, Sander Anneveldt, Carolien M H B Lucas, Herman F J Mannaerts, Elly M C J Wajon, Kenneth Dickstein, Maarten J Cramer, Marcel A J Landman, Arno W Hoes, Frans H Rutten
BACKGROUND: Efficient incorporation of e-health in patients with heart failure (HF) may enhance health care efficiency and patient empowerment. We aimed to assess the effect on self-care of (i) the European Society of Cardiology/Heart Failure Association website 'heartfailurematters.org' on top of usual care, and (ii) an e-health adjusted care pathway leaving out 'in person' routine HF nurse consultations in stable HF patients. METHODS AND RESULTS: In a three-group parallel-randomized trial in stable HF patients from nine Dutch outpatient clinics, we compared two interventions ( heartfailurematters...
November 28, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/30485595/clinical-and-research-implications-of-serum-versus-plasma-potassium-measurements
#16
LETTER
Lauren B Cooper, Gianluigi Savarese, Juan-Jesus Carrero, Barna Szabo, Tomas Jernberg, Åsa Jonsson, Catarina Dahlbom, Ulf Dahlström, Anders Larson, Lars H Lund
No abstract text is available yet for this article.
November 28, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/30485591/cardiac-contractility-modulation-mechanisms-of-action-in-heart-failure-with-reduced-ejection-fraction-and-beyond
#17
REVIEW
Carsten Tschöpe, Behrouz Kherad, Oliver Klein, Axel Lipp, Florian Blaschke, David Gutterman, Daniel Burkhoff, Nazha Hamdani, Frank Spillmann, Sophie Van Linthout
Heart failure (HF) is responsible for substantial morbidity and mortality and is increasing in prevalence. Although there has been remarkable progress in the treatment of HF with reduced ejection fraction (HFrEF), morbidity and mortality are still substantial. Cardiac contractility modulation (CCM) signals, consisting of biphasic high-voltage bipolar signals delivered to the right ventricular septum during the absolute refractory period, have been shown to improve symptoms, exercise tolerance and quality of life and reduce the rate of HF hospitalizations in patients with ejection fractions (EF) between 25% and 45%...
November 28, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/30474896/exercise-training-in-patients-with-ventricular-assist-devices-a-review-of-the-evidence-and-practical-advice-a-position-paper-from-the-committee-on-exercise-physiology-and-training-and-the-committee-of-advanced-heart-failure-of-the-heart-failure-association
#18
Stamatis Adamopoulos, Ugo Corrà, Ioannis D Laoutaris, Massimo Pistono, Pier Giuseppe Agostoni, Andrew J S Coats, Maria G Crespo Leiro, Justien Cornelis, Constantinos H Davos, Gerasimos Filippatos, Lars H Lund, Tiny Jaarsma, Frank Ruschitzka, Petar M Seferovic, Jean-Paul Schmid, Maurizio Volterrani, Massimo F Piepoli
Exercise training (ET) and secondary prevention measures in cardiovascular disease aim to stimulate early physical activity and to facilitate recovery and improve health behaviours. ET has also been proposed for heart failure patients with a ventricular assist device (VAD), to help recovery in the patient's functional capacity. However, the existing evidence in support of ET in these patients remains limited. After a review of current knowledge on the causes of the persistence of limitation in exercise capacity in VAD recipients, and concerning the benefit of ET in VAD patients, the Heart Failure Association of the European Society of Cardiology has developed the present document to provide practical advice on implementing ET...
November 26, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/30468294/endothelial-dysfunction-and-cellular-repair-in-heart-failure-with-preserved-ejection-fraction-response-to-a-single-maximal-exercise-bout
#19
LETTER
Andreas B Gevaert, Paul J Beckers, Amaryllis H Van Craenenbroeck, Katrien Lemmens, Caroline M Van De Heyning, Hein Heidbuchel, Christiaan J Vrints, Emeline M Van Craenenbroeck
No abstract text is available yet for this article.
November 23, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/30468292/heart-failure-with-preserved-ejection-fraction-in-asia-the-far-side-of-the-moon
#20
EDITORIAL
Michele Senni, Annamaria Iorio, Petar Seferović
No abstract text is available yet for this article.
November 23, 2018: European Journal of Heart Failure
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