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European Journal of Heart Failure

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https://www.readbyqxmd.com/read/28653458/left-ventricular-only-pacing-in-heart-failure-patients-with-normal-atrioventricular-conduction-improves-global-function-and-left-ventricular-regional-mechanics-compared-with-biventricular-pacing-an-adaptive-cardiac-resynchronization-therapy-sub-study
#1
Kevin V Burns, Ryan M Gage, Antonia E Curtin, John Gorcsan, Alan J Bank
AIMS: Right ventricular (RV) pacing can impair left ventricular (LV) function. When timed with native RV activation, LV-only pacing may cause greater improvements in LV function than biventricular pacing. This study compared the chronic effects of cardiac resynchronization therapy (CRT) on LV mechanics between biventricular pacing and LV-only pacing in patients with normal atrioventricular (AV) conduction. METHODS AND RESULTS: The Adaptive CRT (aCRT) algorithm provides LV-only pacing timed with native RV activation when the AV interval is normal (≤200 ms during sinus rhythm)...
June 26, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28653358/peripartum-cardiomyopathy-for-the-clinician-the-known-and-the-unknown
#2
EDITORIAL
Uri Elkayam
No abstract text is available yet for this article.
June 26, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28639369/a-network-analysis-to-compare-biomarker-profiles-in-patients-with-and-without-diabetes-mellitus-in-acute-heart-failure
#3
Abhinav Sharma, Biniyam G Demissei, Jasper Tromp, Hans L Hillege, John G Cleland, Christopher M O'Connor, Marco Metra, Piotr Ponikowski, John R Teerlink, Beth A Davison, Michael M Givertz, Daniel M Bloomfield, Howard Dittrich, Dirk J van Veldhuisen, Gad Cotter, Justin A Ezekowitz, Mohsin A F Khan, Adriaan A Voors
AIMS: It is unclear whether distinct pathophysiological processes are present among patients with acute heart failure (AHF), with and without diabetes. Network analysis of biomarkers may identify correlative associations that reflect different pathophysiological pathways. METHODS AND RESULTS: We analysed a panel of 48 circulating biomarkers measured within 24 h of admission for AHF in a subset of patients enrolled in the PROTECT trial. In patients with and without diabetes, we performed a network analysis to identify correlations between measured biomarkers...
June 21, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28627079/persistently-misunderstood-and-malignant-the-case-of-heart-failure-vs-cancer
#4
EDITORIAL
Simon Stewart
No abstract text is available yet for this article.
June 19, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28627045/heart-rate-and-its-reduction-in-chronic-heart-failure-and-beyond
#5
REVIEW
Aleksandra Nikolovska Vukadinović, Davor Vukadinović, Jeffrey Borer, Martin Cowie, Michel Komajda, Mitja Lainscak, Karl Swedberg, Michael Böhm
Heart rate (HR) is associated with cardiovascular outcomes in all the stages of the cardiovascular continuum as well as in patients with pulmonary, cerebrovascular, and renal disease, sepsis, cancer, and erectile dysfunction. In patients with cardiovascular disease, but also in the general population, increased HR represents an important indicator of mortality with each acceleration of HR over 70 b.p.m. increasing the risk. In patients in sinus rhythm with chronic heart failure with reduced ejection fraction (HFrEF), a HR >70 b...
June 19, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28626904/do-real-world-data-support-and-extend-our-ability-to-predict-reverse-remodelling-following-cardiac-resynchronization-therapy-based-on-qrs-morphology-and-width
#6
EDITORIAL
Torkel Steen, Kenneth Dickstein
No abstract text is available yet for this article.
June 19, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28597606/the-mortality-risk-of-deferring-optimal-medical-therapy-in-heart-failure-a-systematic-comparison-against-norms-for-surgical-consent-and-patient-information-leaflets
#7
Sameer Zaman, Saman S Zaman, Timothy Scholtes, Matthew J Shun-Shin, Carla M Plymen, Darrel P Francis, Graham D Cole
AIMS: The prescription of optimal medical therapy for heart failure is often delayed despite compelling evidence of a reduction in mortality. We calculated the absolute risk resulting from delayed prescription of therapy. For comparison, we established the threshold applied by clinicians when discussing the risk for death associated with an intervention, and the threshold used in official patient information leaflets. METHODS AND RESULTS: We undertook a meta-analysis of randomized controlled trials to calculate the excess mortality caused by deferral of medical therapy for 1 year...
June 8, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28597526/primum-non-nocere-the-dangers-of-deferring-heart-failure-therapy
#8
EDITORIAL
Michael Böhm, Ulrich Laufs, Felix Mahfoud, Stephan H Schirmer, Ingrid Kindermann
No abstract text is available yet for this article.
June 8, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28597497/right-ventricular-dysfunction-in-left-sided-heart-failure-with-preserved-versus-reduced-ejection-fraction
#9
Lena Bosch, Carolyn S P Lam, Lingli Gong, Siew Pang Chan, David Sim, Daniel Yeo, Fazlur Jaufeerally, Kui Toh Gerard Leong, Hean Yee Ong, Tze Pin Ng, Arthur Mark Richards, Fatih Arslan, Lieng H Ling
BACKGROUND: Right ventricular (RV) dysfunction is recognized as a major prognostic factor in left-sided heart failure (HF). However, the relative contribution of RV dysfunction in HF with preserved (HFpEF) vs. reduced ejection fraction (HFrEF) is unclear. METHODS AND RESULTS: Right ventricular longitudinal strain (RVLS), tricuspid annular plane systolic excursion (TAPSE) and pulmonary artery systolic pressure (PASP) were determined by echocardiography in 657 age- and gender-matched groups of patients with HFpEF [left ventricular ejection fraction (LVEF) ≥50%; n=219] and HFrEF (LVEF <50%; n=219) and in controls without HF (n=219) from an Asian population-based cohort study...
June 8, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28597481/peripartum-cardiomyopathy-in-denmark-a-retrospective-population-based-study-of-incidence-management-and-outcome
#10
Anne S Ersbøll, Marianne Johansen, Peter Damm, Steen Rasmussen, Niels G Vejlstrup, Finn Gustafsson
AIM: Population-based European studies of peripartum cardiomyopathy (PPCM) are few. We aimed to estimate the nationwide incidence and outcome of PPCM in Denmark during 2005-2014. METHODS AND RESULTS: The Danish National Birth Register and the Danish National Patient Register were linked and searched for cardiomyopathy and heart failure ICD-10 diagnoses in a period of nine months before to 12 months after a delivery from 1 January 2005 through 31 December 2014. Diagnoses were validated and additional data were extracted from patient charts...
June 8, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28585276/hypertrophic-cardiomyopathy-in-mitochondrial-disorders-description-of-an-uncommon-clinical-case
#11
Fabio Marsico, Claudia D'Andrea, Antonio Parente, Fabiana De Martino, Letizia Capasso, Francesco Raimondi, Stefania Paolillo, Santo Dellegrottaglie, Caterina Marciano, Bruno Trimarco, Pasquale Perrone Filardi
No abstract text is available yet for this article.
June 6, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28580774/clinical-utility-of-biomarkers-in-heart-failure
#12
EDITORIAL
Christian Mueller
No abstract text is available yet for this article.
June 5, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28580770/evaluating-pulmonary-congestion-with-lung-ultrasound-and-the-need-to-take-the-next-steps-in-heart-failure
#13
EDITORIAL
Johan Lassus
No abstract text is available yet for this article.
June 5, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28580728/late-graft-failure-in-heart-transplant-recipients-incidence-risk-factors-and-clinical-outcomes
#14
Ángela López-Sainz, Eduardo Barge-Caballero, Gonzalo Barge-Caballero, David Couto-Mallón, María J Paniagua-Martin, Leticia Seoane-Quiroga, Carmen Iglesias-Gil, José M Herrera-Noreña, José J Cuenca-Castillo, José M Vázquez-Rodríguez, María G Crespo-Leiro
AIM: To analyse the incidence, risk factors and clinical outcomes of late graft failure after heart transplantation. METHODS AND RESULTS: We conducted an observational, single-centre study based on 547 patients who underwent cardiac transplantation from 1991 to 2014 and who survived the in-hospital postoperative period. Late graft failure was defined as the first hospitalization due to this condition after discharge. Over a mean follow-up of 8.4 ± 6, 178 (32...
June 5, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28580664/improving-heart-failure-health-is-there-a-secret-swedish-sauce
#15
EDITORIAL
Adam D DeVore, Adrian F Hernandez
No abstract text is available yet for this article.
June 5, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28580625/mineralocorticoid-receptor-antagonist-pattern-of-use-in-heart-failure-with-reduced-ejection-fraction-findings-from-biostat-chf
#16
João Pedro Ferreira, Patrick Rossignol, Jean-Loup Machu, Abhinav Sharma, Nicolas Girerd, Stefan D Anker, John G Cleland, Kenneth Dickstein, Gerasimos Filippatos, Hans L Hillege, Chim C Lang, Jozine Ter Maaten, Marco Metra, Leong Ng, Piotr Ponikowski, Nilesh J Samani, Dirk J van Veldhuisen, Aeilko H Zwinderman, Adriaan Voors, Faiez Zannad
AIMS: Mineralocorticoid receptor antagonists (MRAs) are recommended (unless contraindicated) to all patients with heart failure with reduced ejection fraction (HFrEF). However, MRAs are still largely underused in routine clinical practice. This study aims to describe the determinants and pattern of use of MRAs in HFrEF. METHODS AND RESULTS: BIOSTAT-CHF is a European multicentre, prospective study which enrolled patients suboptimally treated with angiotensin-converting enzyme inhibitors/angiotensin receptor blockers (ACEi/ARBs) and/or beta-blockers, with the aim of optimizing guideline-based use of these agents...
June 5, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28580623/the-relationship-of-circulating-relaxin-2-concentrations-with-short-term-prognosis-in-patients-with-acute-heart-failure-the-relahf-study
#17
Pablo Herrero-Puente, Belén Prieto-García, María García-García, Pere Llorens, Francisco Javier Martín-Sánchez, Javier Jacob, Alexandre Mebazaa, Christian Mueller, Alan S Maisel, Víctor Gil, Pablo García-Hernandez, Òscar Miró
AIMS: This study aimed to determine the frequency of detectable relaxin-2 concentrations and associated factors in patients with acute heart failure (AHF) and to establish relationships with short-term outcome and clinical and analytical parameters. METHODS AND RESULTS: We performed a prospective, analytical, observational, multicentre study with cohort follow-up. We collected sociodemographic variables, previous history, basal status, previous treatment, vital signs, electrocardiographic and analytical data in the emergency department...
June 5, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28560782/benefit-of-cardiopoietic-mesenchymal-stem-cell-therapy-on-left-ventricular-remodelling-results-from-the-congestive-heart-failure-cardiopoietic-regenerative-therapy-chart-1-study
#18
John R Teerlink, Marco Metra, Gerasimos S Filippatos, Beth A Davison, Jozef Bartunek, Andre Terzic, Bernard J Gersh, Thomas J Povsic, Timothy D Henry, Bertrand Alexandre, Christian Homsy, Christopher Edwards, Aymeric Seron, William Wijns, Gad Cotter
AIMS: Left ventricular (LV) reverse remodelling is an important marker of improved outcomes in patients with advanced heart failure (HF). We examined the impact of the intramyocardial administration of bone-marrow-derived, lineage-directed, autologous cardiopoietic mesenchymal stem cells (C3BS-CQR-1) on LV remodelling in patients with advanced HF enrolled in the CHART-1 study. METHODS AND RESULTS: Patients (n=351) with symptomatic advanced HF secondary to ischaemic heart disease, and reduced LV ejection fraction (LVEF <35%) were randomized to receive C3BS-CQR-1 or a sham procedure...
May 31, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28560745/aspirin-in-heart-failure-don-t-throw-the-baby-aspirin-out-with-the-bathwater
#19
EDITORIAL
Raffaele De Caterina
No abstract text is available yet for this article.
May 31, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28560824/emphasis-on-abdominal-obesity-as-a-modifier-of-eplerenone-effect-in-heart-failure-hypothesis-generating-signals-from-emphasis-hf
#20
EDITORIAL
Ali Ahmed, Marc R Blackman, Michel White, Stefan D Anker
No abstract text is available yet for this article.
May 30, 2017: European Journal of Heart Failure
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