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European Journal of Heart Failure

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https://www.readbyqxmd.com/read/29457358/crt-survey-ii-a-european-society-of-cardiology-survey-of-cardiac-resynchronisation-therapy-in-11-088-patients-who-is-doing-what-to-whom-and-how
#1
Kenneth Dickstein, Camilla Normand, Angelo Auricchio, Nigussie Bogale, John G Cleland, Anselm K Gitt, Christoph Stellbrink, Stefan D Anker, Gerasimos Filippatos, Maurizio Gasparini, Gerhard Hindricks, Carina Blomström Lundqvist, Piotr Ponikowski, Frank Ruschitzka, Giovanni Luca Botto, Alan Bulava, Gabor Duray, Carsten Israel, Christophe Leclercq, Peter Margitfalvi, Óscar Cano, Chris Plummer, Nedim Umutay Sarigul, Maciej Sterlinski, Cecilia Linde
BACKGROUND: Cardiac resynchronisation therapy (CRT) reduces morbidity and mortality in appropriately selected patients with heart failure and is strongly recommended for such patients by guidelines. A European Society of Cardiology (ESC) CRT survey conducted in 2008-2009 showed considerable variation in guideline adherence and large individual, national and regional differences in patient selection, implantation practice and follow-up. Accordingly, two ESC associations, the European Heart Rhythm Association and the Heart Failure Association, designed a second prospective survey to describe contemporary clinical practice regarding CRT...
February 19, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29457328/cognitive-performance-in-late-adolescence-and-long-term-risk-of-early-heart-failure-in-swedish-men
#2
Martin Lindgren, Peter Eriksson, Annika Rosengren, Josefina Robertson, Linus Schiöler, Maria Schaufelberger, David Åberg, Kjell Torén, Margda Waern, Maria Åberg
AIMS: Heart failure (HF) incidence appears to increase among younger individuals, raising questions of how risk factors affect the younger population. We investigated the association of cognitive performance in late adolescence with long-term risk of early HF. METHODS AND RESULTS: We followed a cohort of Swedish men enrolled in mandatory military conscription in 1968-2005 (n = 1 225 300; mean age 18.3 years) until 2014 for HF hospitalization, using data from the Swedish National Inpatient Registry...
February 19, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29431288/heart-brain-interactions-in-patients-with-heart-failure-including-takotsubo-syndrome-a-need-to-monitor-autonomic-sympathetic-activity
#3
REVIEW
John E Madias
No abstract text is available yet for this article.
February 12, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29431287/comparison-of-cardiopulmonary-based-risk-models-with-a-clinical-heart-failure-risk-model
#4
EDITORIAL
Wayne C Levy, Todd F Dardas
No abstract text is available yet for this article.
February 12, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29431285/east-asia-may-have-a-better-1-year-survival-following-an-acute-heart-failure-episode-compared-with-europe-results-from-an-international-observational-cohort
#5
LETTER
Eiichi Akiyama, Lucas N L Van Aelst, Mattia Arrigo, Johan Lassus, Òscar Miró, Jelena Čelutkienė, Dong-Ju Choi, Alain Cohen-Solal, Shiro Ishihara, Katsuya Kajimoto, Said Laribi, Aldo Pietro Maggioni, Justina Motiejunaite, Christian Mueller, Jiri Parenica, Jin Joo Park, Naoki Sato, Jindrich Spinar, Jian Zhang, Yuhui Zhang, Kazuo Kimura, Kouichi Tamura, Etienne Gayat, Alexandre Mebazaa
No abstract text is available yet for this article.
February 12, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29431284/increased-blood-lactate-is-prevalent-and-identifies-poor-prognosis-in-patients-with-acute-heart-failure-without-overt-peripheral-hypoperfusion
#6
Robert Zymliński, Jan Biegus, Mateusz Sokolski, Paweł Siwołowski, Sylwia Nawrocka-Millward, John Todd, Ewa A Jankowska, Waldemar Banasiak, Gad Cotter, John G Cleland, Piotr Ponikowski
AIMS: Lactate is produced by anaerobic metabolism and may reflect inadequate tissue perfusion in conditions such as acute heart failure (AHF). We evaluated the prevalence and clinical significance of elevated blood lactate on admission in patients with AHF. METHODS AND RESULTS: We enrolled 237 patients with AHF (mean age 67 ± 12 years; 70% men) presenting without overt clinical evidence of peripheral hypoperfusion ('warm haemodynamic profile'). Median (upper and lower quartiles) blood lactate on admission was 1...
February 12, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29431256/heart-failure-with-mid-range-ejection-fraction-in-charm-characteristics-outcomes-and-effect-of-candesartan-across-the-entire-ejection-fraction-spectrum
#7
Lars H Lund, Brian Claggett, Jiankang Liu, Carolyn S Lam, Pardeep S Jhund, Giuseppe M Rosano, Karl Swedberg, Salim Yusuf, Christopher B Granger, Marc A Pfeffer, John J V McMurray, Scott D Solomon
AIMS: We tested the hypothesis that candesartan improves outcomes in heart failure (HF) with mid-range ejection fraction [HFmrEF; ejection fraction (EF) 40-49%]. METHODS AND RESULTS: In 7598 patients enrolled in the CHARM Programme (HF across the spectrum of EF), we assessed characteristics, outcomes and treatment effect of candesartan according to EF. Patients with HFmrEF (n = 1322, 17%) were similar to those with HF with reduced EF (HFrEF; n = 4323, 57%) with respect to some characteristics, and intermediate between HFrEF and HF with preserved EF (HFpEF; n = 1953, 26%) with respect to others...
February 12, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29431254/guideline-recommendations-for-cardiac-resynchronization-therapy-evolve-but-does-clinical-practice-match-the-pace
#8
EDITORIAL
Camilla Normand, Kenneth Dickstein
No abstract text is available yet for this article.
February 12, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29431251/effect-of-sacubitril-valsartan-on-recurrent-events-in-the-prospective-comparison-of-arni-with-acei-to-determine-impact-on-global-mortality-and-morbidity-in-heart-failure-trial-paradigm-hf
#9
Ulrik M Mogensen, Jianjian Gong, Pardeep S Jhund, Li Shen, Lars Køber, Akshay S Desai, Martin P Lefkowitz, Milton Packer, Jean L Rouleau, Scott D Solomon, Brian L Claggett, Karl Swedberg, Michael R Zile, Guenther Mueller-Velten, John J V McMurray
AIMS: Recurrent hospitalizations are a major part of the disease burden in heart failure (HF), but conventional analyses consider only the first event. We compared the effect of sacubitril/valsartan vs. enalapril on recurrent events, incorporating all HF hospitalizations and cardiovascular (CV) deaths in PARADIGM-HF, using a variety of statistical approaches advocated for this type of analysis. METHODS AND RESULTS: In PARADIGM-HF, a total of 8399 patients were randomized and followed for a median of 27 months...
February 12, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29405611/efficacy-and-safety-of-intermittent-intravenous-outpatient-administration-of-levosimendan-in-patients-with-advanced-heart-failure-the-lion-heart-multicentre-randomised-trial
#10
Josep Comín-Colet, Nicolás Manito, Javier Segovia-Cubero, Juan Delgado, José Manuel García Pinilla, Luis Almenar, María G Crespo-Leiro, Alessandro Sionis, Teresa Blasco, Domingo Pascual-Figal, Francisco Gonzalez-Vilchez, José Luis Lambert-Rodríguez, María Grau, Jordi Bruguera
AIMS: The LION-HEART study was a multicentre, double-blind, randomised, parallel-group, placebo-controlled trial evaluating the efficacy and safety of intravenous administration of intermittent doses of levosimendan in outpatients with advanced chronic heart failure. METHODS AND RESULTS: Sixty-nine patients from 12 centres were randomly assigned at a 2:1 ratio to levosimendan or placebo groups, receiving treatment by a 6-hour intravenous infusion (0.2 μg/kg/min without bolus) every 2 weeks for 12 weeks...
February 6, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29405554/six-month-outcome-after-transcatheter-edge-to-edge-repair-of-severe-tricuspid-regurgitation-in-patients-with-heart-failure
#11
Mathias Orban, Christian Besler, Daniel Braun, Michael Nabauer, Marion Zimmer, Martin Orban, Thilo Noack, Julinda Mehilli, Christian Hagl, Joerg Seeburger, Michael Borger, Axel Linke, Holger Thiele, Steffen Massberg, Joerg Ender, Philipp Lurz, Jörg Hausleiter
AIMS: Severe tricuspid regurgitation (TR) is common in patients with right-sided heart failure (HF) and causes substantial morbidity and mortality. Treatment options beyond medical therapy are limited for high-risk patients. Transcatheter edge-to-edge tricuspid valve (TV) repair showed procedural safety and short-term efficacy. Impact on mid-term outcome is unclear. This dual-centre observational study evaluates the mid-term safety, efficacy and clinical outcome after edge-to-edge TV repair for severe TR in patients with HF...
February 6, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29405513/renin-angiotensin-system-inhibition-it-s-been-a-long-but-fruitful-journey
#12
EDITORIAL
John J V McMurray
No abstract text is available yet for this article.
February 6, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29405511/a-flattening-oxygen-consumption-trajectory-phenotypes-disease-severity-and-poor-prognosis-in-patients-with-heart-failure-with-reduced-mid-range-and-preserved-ejection-fraction
#13
Dejana Popovic, Ross Arena, Marco Guazzi
BACKGROUND: In heart failure (HF), a flattening oxygen consumption (VO2 ) trajectory during cardiopulmonary exercise test (CPET) reflects an acutely compromised cardiac output. We hypothesized that a flattening VO2 trajectory is helpful in phenotyping disease severity and prognosis in HF with either reduced (HFrEF), mid-range (HFmrEF), or preserved (HFpEF) ejection fraction. METHODS AND RESULTS: Overall, 319 HF patients (198 HFrEF, 80 HFmrEF, and 41 HFpEF) underwent CPET...
February 6, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29388294/you-do-something-to-me-something-deep-inside
#14
EDITORIAL
Walter M van den Bergh, Joep M Droogh, Kevin Damman
No abstract text is available yet for this article.
January 31, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29368374/the-promise-of-patient-reported-outcomes-one-step-closer-to-routine-care
#15
EDITORIAL
Jonathan G Howlett
No abstract text is available yet for this article.
January 25, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29368369/recent-developments-and-controversies-in-transcatheter-aortic-valve-implantation
#16
REVIEW
Noman Ali, Peysh A Patel, Steven J Lindsay
Interventional cardiology has been revolutionised by transcatheter aortic valve implantation (TAVI), which has become established as the benchmark treatment for severe aortic stenosis in patients at high risk for surgical aortic valve replacement (AVR). Increased procedural familiarity and progression in device technology has enabled improvements to be made in complication rates, which have led to a commensurate expansion in the use of TAVI; it is now a viable alternative to AVR in patients at intermediate surgical risk, and has been used in cohorts such as those with bicuspid aortic valves or pure, severe aortic regurgitation...
January 25, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29336093/heart-failure-with-mid-range-ejection-fraction-causes-and-consequences
#17
EDITORIAL
Jasper Tromp, Adriaan A Voors, Carolyn S P Lam
No abstract text is available yet for this article.
January 16, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29333691/the-innate-immune-system-in-chronic-cardiomyopathy-a-european-society-of-cardiology-esc-scientific-statement-from-the-working-group-on-myocardial-function-of-the-esc
#18
REVIEW
Stefan Frantz, Ines Falcao-Pires, Jean-Luc Balligand, Johann Bauersachs, Dirk Brutsaert, Michele Ciccarelli, Dana Dawson, Leon J de Windt, Mauro Giacca, Nazha Hamdani, Denise Hilfiker-Kleiner, Emilio Hirsch, Adelino Leite-Moreira, Manuel Mayr, Thomas Thum, Carlo G Tocchetti, Jolanda van der Velden, Gilda Varricchi, Stephane Heymans
Activation of the immune system in heart failure (HF) has been recognized for over 20 years. Initially, experimental studies demonstrated a maladaptive role of the immune system. However, several phase III trials failed to show beneficial effects in HF with therapies directed against an immune activation. Preclinical studies today describe positive and negative effects of immune activation in HF. These different effects depend on timing and aetiology of HF. Therefore, herein we give a detailed review on immune mechanisms and their importance for the development of HF with a special focus on commonalities and differences between different forms of cardiomyopathies...
January 15, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29333673/predicting-heart-failure-one-size-does-not-fit-all
#19
EDITORIAL
Jasper Tromp, Peter van der Meer
No abstract text is available yet for this article.
January 15, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29333669/blood-pressure-and-goal-titration-of-neurohormonal-antagonists-the-tortoise-wins-again
#20
EDITORIAL
Hector O Ventura, Mandeep R Mehra
No abstract text is available yet for this article.
January 15, 2018: European Journal of Heart Failure
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