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Veterinary Ophthalmology

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https://www.readbyqxmd.com/read/27905668/subconjunctival-antimicrobial-poloxamer-gel-for-treatment-of-corneal-ulceration-in-stranded-california-sea-lions-zalophus-californianus
#1
Claire A Simeone, Carmen M H Colitz, Kathleen M Colegrove, Cara L Field, Carlos Rios, Heather L Chandler, Shawn P Johnson
OBJECTIVE: Corneal ulcers are commonly encountered in pinnipeds. Prolonged oral antibiotics and topical ophthalmic solutions may not be practical to administer, and novel treatment techniques are desired. Thermodynamic gels are a potential solution because they hold antimicrobials at the site of injection, slowly releasing drug. This study investigated the clinical efficacy of antibiotic-impregnated poloxamer gel in management of corneal ulceration. ANIMAL STUDIED: Twenty-six California sea lions undergoing rehabilitation at The Marine Mammal Center...
December 1, 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27896899/characterization-of-a-novel-form-of-progressive-retinal-atrophy-in-whippet-dogs-a-clinical-electroretinographic-and-breeding-study
#2
André Tavares Somma, Juan Carlos Duque Moreno, Mario Teruo Sato, Blanche Dreher Rodrigues, Marianna Bacellar-Galdino, Laurence Mireille Occelli, Simon Michael Petersen-Jones, Fabiano Montiani-Ferreira
OBJECTIVE: To describe a form of progressive retinal atrophy (PRA) in Whippets including clinical, electroretinographic, optical coherence tomographic changes and pedigree analysis. ANIMALS STUDIED: Client-owned Whippet dogs (n = 51) living in Brazil. PROCEDURES: All animals were submitted for routine ophthalmic screening for presumed inherited ocular disease, which included the following: visual tests, such as obstacle course tests, in scotopic and photopic conditions, cotton ball test, dazzle reflex, ocular fundus evaluation by indirect ophthalmoscopy followed by fundus photography...
November 29, 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27882744/transpalpebral-exenteration-in-cattle-a-retrospective-study-of-115-cases
#3
Munashe Chigerwe, John A Angelos, Lisa Gamsjäeger, Meera C Heller
OBJECTIVE: To describe the indications for exenteration and complications associated with the procedure. ANIMALS STUDIED: 115 cattle. PROCEDURES: Medical records of cattle presented for unilateral exenteration evaluated at the University of California, Davis Veterinary Medical Teaching Hospital from January 1985 through December 2015 were reviewed. RESULTS: Median (range) age at presentation for all cattle was 6 (0.2-30) years...
November 24, 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27882675/calibration-of-the-tonovet-and-tono-pen-vet-tonometers-in-the-porcine-eye
#4
Andrew C Lewin, Paul E Miller
OBJECTIVE: The pig has an increasingly important role in ocular drug delivery models, but the most accurate tonometer in this species is unknown. The purpose of this study was to evaluate the accuracy of TonoVet and Tono-Pen Vet tonometers in the ex vivo porcine eye. PROCEDURE: Four freshly enucleated normal porcine eyes were cannulated with two 25-gauge needles; one connected via tubing to a mercury manometer calibrated continuous physiologic recorder and the other connected to a reservoir of lactated Ringer's solution on an adjustable stand...
November 24, 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27878931/abstracts
#5
(no author information available yet)
No abstract text is available yet for this article.
November 22, 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27860168/use-of-a-350-mm-2-baerveldt-glaucoma-drainage-device-to-maintain-vision-and-control-intraocular-pressure-in-dogs-with-glaucoma-a-retrospective-study-2013-2016
#6
Kathleen L Graham, David Donaldson, Francis A Billson, F Mark Billson
OBJECTIVE: To evaluate the 350-mm(2) Baerveldt glaucoma drainage device (GDD) in dogs with refractory glaucoma when modifications to address postoperative hypotony (extraluminal ligature; intraluminal stent) and the fibroproliferative response (intraoperative Mitomycin-C; postoperative oral colchicine and prednisolone) are implemented as reported in human ophthalmology. DESIGN: Retrospective case series. ANIMALS: Twenty-eight client-owned dogs (32 eyes) including seven dogs (nine eyes) with primary glaucoma and 21 dogs (23 eyes) with secondary glaucoma...
November 16, 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27862797/ocular-biometry-by-computed-tomography-in-different-dog-breeds
#7
Carolin L H Chiwitt, Stephen J Baines, Paul Mahoney, Andrew Tanner, Christine L Heinrich, Michael Rhodes, Heidi J Featherstone
OBJECTIVE: To (i) correlate B-mode ocular ultrasound (US) and computed tomography (CT) (prospective pilot study), (ii) establish a reliable method to measure the normal canine eye using CT, (iii) establish a reference guide for some dog breeds, (iv) compare eye size between different breeds and breed groups, and (v) investigate the correlation between eye dimensions and body weight, gender, and skull type (retrospective study). PROCEDURE: B-mode US and CT were performed on ten sheep cadaveric eyes...
November 11, 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27860098/epidemiology-of-ocular-disorders-presumed-to-be-inherited-in-three-large-italian-dog-breeds-in-italy
#8
Adolfo Guandalini, Nicola Di Girolamo, Daniele Santillo, Valentina Andreani, Roberta Corvi, Marina Bandini, Claudio Peruccio
OBJECTIVE: To describe the epidemiology and the types of eye disorders that are presumed to be inherited (PIED) in three large Italian dog breeds. ANIMALS: Three large Italian dog breeds: Neapolitan Mastiff (FCI code: 197), Maremma Sheepdog (FCI code: 201), and Italian Corso dog (FCI code: 343). PROCEDURES: All dogs that underwent a complete ophthalmic examination between 1992 and 2012 were included in this prospective observational study...
November 11, 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27791324/effect-of-topical-ophthalmic-latanoprost-0-005-solution-alone-and-in-combination-with-diclofenac-0-1-solution-in-healthy-horses-a-pilot-study
#9
Kyle Tofflemire, Elizabeth M Whitley, Rachel Allbaugh, Gil Ben-Shlomo, Angela Griggs, Travis Strong, R David Whitley
OBJECTIVE: To evaluate the effect of topical ophthalmic 0.005% latanoprost alone and in combination with 0.1% diclofenac on healthy horses. ANIMALS STUDIED: Twelve healthy adult horses. PROCEDURES: A randomized, masked crossover design was used with horses divided into three groups for once daily treatment in one randomly selected eye. For arm 1 of the study, Group D (n = 3) received 0.1% diclofenac, Group L (n = 3) received 0.005% latanoprost, and Group DL (n = 6) received 0...
October 28, 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27761982/assessment-of-tear-film-osmolarity-using-the-tearlab-%C3%A2-osmometer-in-normal-dogs-and-dogs-with-keratoconjunctivitis-sicca
#10
Lionel Sebbag, Shin Ae Park, Philip H Kass, David J Maggs, Mayssa Attar, Christopher J Murphy
OBJECTIVE: To evaluate repeatability and reproducibility of tear osmolarity measured using the TearLab(™) osmometer in normal dogs and to assess its diagnostic potential in dogs with keratoconjunctivitis sicca (KCS). ANIMALS STUDIED: Beagle dogs; six normal and five with KCS. PROCEDURES: Tear osmolarity and Schirmer tear test-1 (STT-1) values were obtained at various times. Normal dogs were assessed for diurnal variation and repeatability and reproducibility of measurements...
October 20, 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27734587/canine-panuveitis-a-retrospective-evaluation-of-55-cases-2000-2015
#11
Benjamin E Bergstrom, Jean Stiles, Wendy M Townsend
OBJECTIVE: To determine the most common etiologies of panuveitis in a group of dogs, patient response to therapy, and visual outcome. DESIGN: Retrospective study. MATERIALS AND METHODS: Medical records of 55 dogs diagnosed with panuveitis at the Purdue University Veterinary Teaching Hospital between December 2000 and December 2015 were reviewed. Data collected included signalment, season of diagnosis, descriptions of ocular lesions, diagnostic testing, treatment protocols, etiologic diagnoses (when determined), and visual outcome...
October 12, 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27641998/aspergillus-spp-panophthalmitis-with-intralenticular-invasion-in-dogs-report-of-two-cases
#12
Penelope J Wooff, Darryl D Dees, Leandro Teixeria
This case series describes the ocular, clinical and histologic manifestations of disseminated Aspergillosis in two dogs. Two dogs presented for severe unilateral panophthalmitis and secondary glaucoma with positive Aspergillus spp. titers. Case 1 showed no clinicopathologic systemic symptoms of fungal dissemination, however, case 2 was affected with acute renal failure. The affected eye of case 1 did not respond to medical therapy and was enucleated for comfort. The affected eye of case 2 responded to aggressive topical and systemic medical therapies, however, the patient was euthanized for acute renal failure...
September 19, 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27624923/intraocular-pressure-in-the-smallest-primate-aging-model-the-gray-mouse-lemur
#13
Marko Dubicanac, Marine Joly, Julia Strüve, Ingo Nolte, Nadine Mestre-Francés, Jean-Michel Verdier, Elke Zimmermann
OBJECTIVE: The aim of this study was to assess the practicability of common tonometers used in veterinary medicine for rapid intraocular pressure (IOP) screening, to calibrate IOP values gained by the tonometers, and to define a reference IOP value for the healthy eye in a new primate model for aging research, the gray mouse lemur. STUDIED ANIMALS AND PROCEDURES: TonoVet(®) and the TonoPen(™) measurements were calibrated manometrically in healthy enucleated eyes of mouse lemurs euthanized for veterinary reasons...
September 13, 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27624855/canine-ocular-onchocerciasis-a-retrospective-review-of-the-diagnosis-treatment-and-outcome-of-16-cases-in-new-mexico-2011-2015
#14
Nancy Johnstone McLean, Kimberly Newkirk, Coenraad M Adema
OBJECTIVE: To describe the clinical exam findings, treatment and outcomes of 16 dogs diagnosed with ocular onchocerciasis in New Mexico. MATERIALS AND METHODS: Records of dogs diagnosed by the primary author were reviewed (2011-2015). Records that were accessible and included a diagnosis of Onchocerca lupi by histopathologic or molecular identification of the nematode were included. RESULTS: Sixteen cases were included. 3/16 dogs were treated with year-round heartworm prophylaxis prior to infection...
September 13, 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27624739/heat-shock-protein-70-expression-in-the-equine-cornea
#15
Cornelia Peterson, Elizabeth Driskell, David Wilkie, Christopher Premanandan, Ralph Hamor
OBJECTIVE: Expression of the 70-kDa heat-shock protein (HSP70) has been demonstrated in normal canine corneal epithelium, and inducible expression has been suggested to facilitate wound resolution through organized migration, proliferation, and adhesion of the corneal epithelial cells. Diminished expression of HSP70 may therefore contribute to prolonged healing in the pathologic cornea of other companion animal species, including the horse. ANIMAL STUDIED: Normal and pathologic equine cornea was evaluated to determine whether the expression of HSP70 is correlated with appropriate corneal epithelial wound healing...
September 13, 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27805324/abstracts
#16
(no author information available yet)
No abstract text is available yet for this article.
November 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/26559782/molecular-mechanisms-of-suberoylanilide-hydroxamic-acid-in-the-inhibition-of-tgf-%C3%AE-1-mediated-canine-corneal-fibrosis
#17
Kristina M Gronkiewicz, Elizabeth A Giuliano, Ajay Sharma, Rajiv R Mohan
OBJECTIVE: To investigate molecular mechanisms mediating anti-fibrotic effect of SAHA in the canine cornea using an in vitro model. We hypothesized that SAHA attenuates corneal fibrosis by modulating Smad-dependent and, to a lesser extent, Smad-independent signaling pathways activated by TGF-β1, as well as matrix metalloproteinase (MMP) activity. METHODS: Cultured canine corneal fibroblasts (CCF) were incubated in the presence/absence of TGF-β1 (5 ng/mL) and SAHA (2...
November 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/26522500/retrobulbar-pigmented-peripheral-nerve-sheath-tumor-in-a-dog
#18
Elizabeth Curto, Alison B Clode, Jessica Durrant, Keith W Montgomery, Brian C Gilger
A 1-year-old male castrated Pug was referred for unilateral exophthalmos unresponsive to oral antibiotic and anti-inflammatory therapy. Clinical findings included exophthalmos of the left eye with lateral strabismus, resistance to retropulsion, and an elevated nictitans. Hematologic and biochemical analyses were within normal limits. Findings following computed tomography (CT) of the head included an expansile retrobulbar soft tissue mass with bony lysis extending into the left nasal cavity and nasopharynx...
November 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27385348/abstracts
#19
(no author information available yet)
No abstract text is available yet for this article.
September 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/26522379/bacterial-isolates-antimicrobial-susceptibility-and-clinical-characteristics-of-bacterial-keratitis-in-dogs-presenting-to-referral-practice-in-australia
#20
Kate E Hindley, Allyson D Groth, Martyn King, Kathleen Graham, F Mark Billson
OBJECTIVE: To identify clinical characteristics, bacterial isolates, and their antimicrobial susceptibility patterns in a prospective study of dogs presenting with suspected bacterial keratitis to aid selection of appropriate therapy. ANIMALS: Seventy-one client-owned dogs presenting to two referral hospitals in Australia. PROCEDURE: Corneal swabs and clinical information were collected from dogs presenting with suspect bacterial keratitis from April 2012 to December 2014...
September 2016: Veterinary Ophthalmology
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