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Nuclear Medicine Review. Central & Eastern Europe

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https://www.readbyqxmd.com/read/29319141/the-use-of-67ga-scintigraphy-in-patients-with-sarcoidosis
#1
Ewa Malinowska, Anna Doboszyńska, Anna Śliwińska, John R Buscombe, Grzegorz Kulesza, Beata Moczulska, Jarosław B Ćwikła
Sarcoidosis is a systemic disease of unknown aetiology characterised by the formation of noncaseating granulomas in various organs and tissues. The various imaging modalities that are useful in the investigation of lesions, staging and establishing indications for treatment include: conventional radiography, CT, MRI, and scintigraphy with 67Ga, 201Tl, 99mTc sestamibi, and somatostatin receptor scintigraphy (SRS) as well as 18F-FDG-PET/CT. This paper discusses the most commonly used of the scintigraphic technique, gallium (67Ga) citrate) and its role in the evaluation and monitoring of patients with sarcoidosis...
January 10, 2018: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/29319140/significance-of-splenic-uptake-on-somatostatin-receptor-imaging-studies
#2
Ismet Sarikaya, Ali Sarikaya, Naheel Alnafisi, Saud Alenezi
Spleen shows high physiological uptake on radionuclide somatostatin receptor (SSTR) imaging studies. Autoradiography and immunohistochemistry studies showed that SSTRs are mainly located in the red pulp of the spleen. In this review article we will summarize the significance of splenic uptake in SSTR imaging studies and will also present high resolution splenic images of Ga-68 DOTANOC PET in which splenic distribution of the radiotracer appears to be correlating with the distribution of red pulp.
January 10, 2018: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/29319139/the-role-of-99mtc-dtpa-retrobulbar-spect-in-staging-and-follow-up-of-graves-orbitopathy
#3
László Galuska, Sándor Barna, József Varga, Ildikó Garai, Endre V Nagy
The pathogenesis of Graves' orbitopathy (GO) is not completely understood. Coexistent hyperfunction of the thyroid gland is frequent; however, GO may also coexist with hypo- or euthyrodism. The course of GO is largely independent of thyroid function, although elevated serum TSH is known to negatively interfere with GO course. GO is severe in 10 % of the cases; sight threatening complications may also develop. A successful therapy of GO requires the assesment of both the severity and activity of orbital inflammation...
January 10, 2018: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/29319138/calibration-factor-fluctuations-for-radiological-protection-instruments-used-in-nuclear-medicine-departments-experience-from-clor
#4
Kamil Szewczak, Iwona Słonecka, Katarzyna Wołoszczuk, Zuzanna Podgórska, Łukasz Modzelewski
The paper presents the capabilities of CLOR's facility for calibrating radiological protection instruments and the important conclusions drawn from the results of calibrating instruments used in Nuclear Medicine Departments in Poland. The analysis was based on results of the certified calibration of chosen instruments. The result for five types of instruments dedicated for dose rate and contamination measurements were presented. They prove the importance of the calibration process. They show that the calibration factor for one particular instrument may fluctuate by 50% in a one year period as well as by more than 100% for two instruments of the same type...
January 10, 2018: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/29319137/a-study-on-drug-delivery-tracing-with-radiolabeled-mesoporous-hydroxyapatite-nanoparticles-conjugated-with-2dg-dox-for-breast-tumor-cells
#5
Mahdiyeh Shamsi, Jafar Majidi Zolbanin, Babak Mahmoudian, Naime Majidi Zolbanin, Leili Aghebati Maleki, Mohammad Asghari Jafarabadi, Jalil Pirayesh Islamian
BACKGROUND: Mesoporous nanoparticles have a great potential in targeted therapy approaches due to their ideal properties for encapsulation of various drugs, proteins and also biologically active molecules. MATERIAL AND METHODS: We used mesoporous hydroxyapatite (HA) nanoparticles as a drug carrier and developed radiolabeled mesoporous HA containing of 2-deoxy-D-glucose (2DG) and Doxorubicin (DOX) with technetium-99m (99mTc) for imaging in in vitro and in vivo studies...
January 10, 2018: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/29319136/the-use-of-99mtc-phytate-for-assessment-the-protective-effect-of-vitamin-e-against-hepatotoxicity-induced-by-methotrexat-in-rat
#6
Hossein Amirfakhrian, Seyed Mohammad Abedi, Hossein Sadeghi, Soheil Azizi, Seyed Jalal Hosseinimehr
In this study, we investigated the protective effect of vitamin E against methotrexate (MTX)-induced hepatotoxicity by quantitative liver 99mTc-phytate uptake and liver imaging and to compare its effect with histopathology in rat. Rats were divided into five groups as control, solvent, Vit E (100 mg/kg), MTX (20 mg/kg), Vit E + MTX and. Vit E was intraperitoneally administrated for 17 days before MTX injection and continued for 4 days. 99mTc-phytate was injected through the tail of rats after the drug administration...
January 10, 2018: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/29319135/radiosynoviorthesis-of-acromioclavicular-joint-using-169er-citrate-prospective-evaluation-of-efficacy
#7
Marika Vereb, Knut Liepe, Manfred Fischer, Lucia Kaliska, Lucia Noskovicova, Sona Balogova
BACKGROUND: There is a clinical need for therapeutic alternative in patients with persisting painful arthritis of AC-joint and failure of previous treatments. However, no radiopharmaceutical is currently explicitly approved for radiosynoviorthesis of acromioclavicular joint. The aim of our study was to prospectively assess the efficacy and safety of radiosynoviorthesis of acromioclavicular joint using erbium-169 citrate. MATERIAL AND METHODS: Radiosynoviorthesis of acromioclavicular joint was performed in 51 consecutive patients (18 males, 33 females) mean age 64...
January 10, 2018: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/29319134/diagnostic-accuracy-of-planar-spect-and-spect-ct-parathyroid-scintigraphy-protocols-in-patients-with-hyperparathyroidism
#8
Yutapong Raruenrom, Daris Theerakulpisut, Nantaporn Wongsurawat, Charoonsak Somboonporn
BACKGROUND: Several parathyroid scintigraphy protocols have been used for preoperative localization of hyperfunctioning parathyroid glands in patients with hyperparathyroidism. The aim of this study is to compare the diagnostic accuracy of various parathyroid scintigraphy protocols. MATERIAL AND METHODS: A retrospective diagnostic accuracy study with histopathology as the reference standard was done. Five imaging protocols were investigated including planar dual tracer Tc-99m pertechnetate/Tc-99m sestamibi (DT), planar dual phase Tc-99m sestamibi (DP), and combined dual tracer dual phase (DTDP) protocols, as well as add-on single photon emission computed tomography (SPECT), and single photon emission computed tomography/computed tomography (SPECT/CT)...
January 10, 2018: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/29319133/the-assessment-of-testosterone-and-radioisotopic-index-of-bone-metabolism-and-bone-mineral-density-in-men-with-testosterone-deficiency-after-one-year-of-testosterone-therapy
#9
Wieslaw Tryniszewski, Grzegorz Kamiński, Zbigniew Maziarz, Michal Nowak, Mariusz Gadzicki, Maciej Radek
BACKGROUND: Testosterone deficiency in men is characterized by typical symptoms of hypogonadism and negative influence on the preservation of bone mass. In this study, we analysed the relationship between testosterone concentration and bone metabolism. Moreover, we assessed the impact of one-year compensation of testosterone deficiency in elderly men on bone metabolism and bone mineral density. Radioisotopic methods of bone metabolism assessment provide new research opportunities. MATERIALS AND METHODS: Men with total testosterone concentration (TT) ≤ 3 ng/ml were included into this study...
January 10, 2018: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/29319132/evaluation-of-changes-in-perfusion-defect-and-left-ventricular-systolic-function-using-tc-99m-tetrofosmin-single-photon-emission-computed-tomography-over-3-month-period-in-patients-of-acute-myocardial-infarction-undergoing-primary-angioplasty
#10
Anil Kumar Avs, P G Kumar, Ajay Swami, Yiteedra Dinker
BACKGROUND: After a primary transluminal coronary angioplasty (PTCA) following AMI (acute myocardial infarction), the perfusion defect and LV (left ventricular) function recover/change over a period of time. The analysis immediately after the procedure may not be true depiction of the exact success of the procedure. There is varying and scanty information available on the natural course of changes in these parameters after a successful PTCA. We hypothesized that majority of change occurs at 3-4 month period...
January 10, 2018: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/29442356/editorial
#11
Grzegorz Kamiński
No abstract text is available yet for this article.
2018: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/29442355/calendar-of-events-2018-overview
#12
Calendar Of Events
No abstract text is available yet for this article.
2018: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/29442354/in-memoriam
#13
In Memoriam
Professor Julian Liniecki, the doyen of nuclear medicine in Poland, co-founder as well as first and long-term (1998-2010) Editor-in-Chief of Nuclear Medicine Review - Central & Eastern Europe passed away on November 25, 2017 at the age of 87.
2018: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/29442349/18f-fdg-avid-sclerosing-angiomatoid-nodular-transformation-sant-of-spleen-on-pet-ct-a-rare-mimicker-of-metastasis
#14
Punit Sharma
Sclerosing Angiomatoid Nodular Transformation (SANT) is a rare benign vascular tumor of spleen. It consists of multiple angiomatoid nodules surrounded by dense fibrous tissue that often coalesces centrally to form a scar, which is considered to be a characteristic feature. These are usually asymptomatic and incidentally detected on imaging for other underlying pathology. SANTs can be 18F-Fluorodeoxyglucose (18F-FDG) avid on positron emission tomography-computed tomography (PET-CT) and thus can lead to false positive finding in oncological patients...
2018: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/29442348/quantitation-in-dextrocardia-on-myocardial-perfusion-imaging-how-to-perform-quantitative-analysis-using-cedars-sinai-software
#15
Mohsen Qutbi, Mehdi Soltanshahi, Mojtaba Ansari, Hoda Hashemi, Isa Neshandar Asli, Babak Shafiei
Dextrocardia, although a rare cardiac abnormality, carries the same risk for cardiac events as other people. SPECT Myocardial perfusion imaging is a potentially helpful diagnostic tool in patients with dextrocardia. Because of swapping of lateral and septal walls on SPECT slices, although visual analysis is possible, quantitation is substantially limited. Here, we introduce a simple practical method to make quantitative analysis feasible and accurate.
2018: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/29442347/f-18-fdg-pet-ct-in-pulmonary-artery-sarcoma-clinical-vignette
#16
Stjepan Hmelik, Margareta Dobrenić, Dražen Huić
Pulmonary artery sarcomas (PAS's) are extremely rare malignant tumors that arise from the endothelial lining of the pulmonary arteries. On CT scans PAS's appear as intraluminal filling defects in the pulmonary arteries, mimicking pulmonary embolism (PE). Due to the similarities in radiographic features as well as in clinical presentation, PAS's are usually misdiagnosed as pulmonary embolism. Since PASs are F-18 FDG avid, F-18 FDG PET/CT scan is a useful imaging tool for differentiating between these two conditions, as shown in this case report...
2018: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/29442346/modification-of-a-two-blood-sample-method-used-for-measurement-of-gfr-with-99mtc-dtpa
#17
Marian J Surma, Anna Płachcińska, Jacek Kuśmierek
BACKGROUND: Measurements of GFR may be performed with a slope/intercept method (S/I), using only two blood samples taken in strictly defined time points. The aim of the study was to modify this method in order to extend time intervals suitable for blood sampling. Modification was based on a variation of a Russel et al. model parameter, selection of time intervals suitable for blood sampling and assessment of uncertainty of calculated results. MATERIAL AND METHODS: Archived values of GFR measurements of 169 patients with different renal function, from 5...
2018: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/28555452/selected-abstracts-of-the-20th-congress-of-the-hevesy-gy%C3%A3-rgy-hungarian-society-of-nuclear-medicine-budapest-may-25-27-2017
#18
Garai Ildikó
No abstract text is available yet for this article.
2017: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/28555451/editorial
#19
Grzegorz Kamiński
No abstract text is available yet for this article.
2017: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/28555450/usefulness-of-parametric-renal-clearance-images-in-the-assessment-of-basic-risk-factors-for-renalnal-clearance-images-in-the-assessment-of-basic-risk-factors-for-renal-scarring-in-children-with-recurrent-urinary-tract-infections
#20
Ewa Pietrzak-Stelasiak, Małgorzata Bieńkiewicz, Wojciech Woźnicki, Krystyna Bubińska, Magdalena Kowalewska-Pietrzak, Anna Płachcińska, Jacek Kuśmierek
BACKGROUND: Clinically confirmed incidents of acute pyelonephritis (APN) following recurrent infections of urinary tract (UTI) form basic risk factors for renal scarring in children. Vesico-uretheral reflux (VUR) of higher grade is additional risk factor for this scarring. Opinions on diagnostic value of summed sequential images of renal uptake phase (SUM) of dynamic renal scintigraphy in detection of renal scars are diverse. However, several publications point to higher diagnostic efficacy of clearance parametric images (PAR) generated from this study...
2017: Nuclear Medicine Review. Central & Eastern Europe
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