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Pediatrics International: Official Journal of the Japan Pediatric Society

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https://www.readbyqxmd.com/read/28901668/dilatation-of-the-ductus-arteriosus-by-diazoxide-in-fetal-and-neonatal-rats
#1
Katsuaki Toyoshima, Kazuo Momma, Tetsuko Ishii, Toshio Nakanishi
BACKGROUND: Diazoxide, an ATP-sensitive potassium channel opener, is the main therapeutic agent for treating hyperinsulinemic hypoglycemia. We aimed to determine the in vivo ductus-dilating effects of diazoxide in fetal and neonatal rats. METHODS: Near-term rat pups delivered via a cesarean section were housed at 33°C. After rapid whole-body freezing, The ductus arteriosus (DA) diameter was measured using a microscope and a micrometer. Full-term pregnant rats (gestational day 21) were intraperitoneally injected with diazoxide (10 and 100 mg/kg) 4 h before delivery, and the neonatal DA diameter was measured at 0, 30, or 60 min after birth...
September 13, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28892213/evaluation-of-longitudinal-and-radial-left-ventricular-functions-using-two-and-three-dimensional-echocardiography-before-and-after-intravenous-immunoglobulin-administration-in-patients-with-acute-kawasaki-disease
#2
Ikuo Hashimoto, Yu Saitou, Nao Sakata, Ko Shibata
BACKGROUND: The relationship between left ventricular (LV) function and longitudinal or radial contraction has not yet been elucidated in patients with acute Kawasaki disease (KD), especially before and after intravenous immunoglobulin (IVIG) administration. METHODS: We studied 28 KD patients without coronary aneurysms (average 3.2 years). The LV end-diastolic volume (LVEDV), end-systolic volume (LVESV), stroke volume (LVSV), and ejection fraction (LVEF) were assessed using three-dimensional echocardiography before IVIG, after IVIG administration, and in the convalescent phase...
September 11, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28892211/early-menarche-is-associated-with-non-alcoholic-fatty-liver-disease-in-adulthood
#3
Kyung Hee Yi, Jin Soon Hwang, Se Won Lim, Jun Ah Lee, Dong Ho Kim, Jung Sub Lim
BACKGROUND: The aim of this study was to examine the association between early menarche (<12 years) and non-alcoholic fatty liver disease (NAFLD) in premenopausal women and to explore whether it is mediated by adult obesity and insulin resistance. METHODS: We analyzed data of premenopausal women, aged 15 or older, from the Korea National Health and Nutrition Examination Survey (2007-2009). We divided the women into 3 groups: early menarche, reference (12.00-15...
September 11, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28891268/pediatric-respiratory-tract-diseases-chronological-trends-and-perspectives
#4
Houda Ben Ayed, Sourour Yaïch, Maïssa Ben Jmaa, Jihene Jedidi, Mariem Ben Hmida, Maroua Trigui, Mondher Kassis, Raouf Karray, Yosra Mejdoub, Habib Feki, Jamel Damak
BACKGROUND: We aimed to draw the epidemiological profile of respiratory tract diseases (RTD) among children in the region of Sfax and to evaluate their current trends over a 13-year period. METHODS: We conducted a retrospective study including all children hospitalized with RTD aged under 14 years. We collected data from the regional morbidity register of the university hospital of Sfax from 2003 to 2015. RESULTS: We included 10797 cases with RTD among 49880 pediatric hospitalizations (21...
September 10, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28891253/effect-of-traditional-chinese-and-western-medicine-on-nocturnal-enuresis-in-children-and-its-influencing-factors-a-randomized-controlled-trial
#5
Yanli Ma, Xiaomei Liu, Ying Shen
BACKGROUND: Nocturnal enuresis (NE) is a common pediatric developmental disorder. Desmopressin is frequently used for NE and is an evidence-based therapy.The Suoquan capsule is a Chinese medicine commonly used for treating NE in children but is poorly understood by most scholars. METHODS: A total of 369 children with NE were randomized to receive treatments consisting of Suoquan, desmopressin plus Suoquan, desmopressin, or behavioral interventions for two months...
September 10, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28871612/a-short-cut-diagnostic-tool-in-cystinosis-bone-marrow-aspiration
#6
Serra Sürmeli Döven, Ali Delibaş, Uğur Raşit Karacan, Selma Ünal
BACKGROUND: Cystinosis is a rare metabolic genetic disorder caused by a mutation in the cystinosin lysosomal cystine transporter (CTNS) gene. The diagnosis of nephropathic cystinosis (NC) is made by observing corneal cystine crystals and/or measuring the cystine content of leukocytes. Analysis by the CTNS gene mutation confirms the diagnosis of cystinosis. But leukocyte cystine level measurement and CTNS gene analysis haven't been widely available and cystine crystals in the cornea may not be apparent in the first months of life...
September 4, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28862773/trends-in-outcomes-of-very-preterm-infants-in-romania-a-tale-of-three-cities
#7
Laura Mihaela Suciu, Lucian Puscasiu, Manuela Cucerea, Bela Szabo, Maria Livia Ognean, Olimpia Petrescu, Dan Ștefan Sîmpălean, Edward F Bell
BACKGROUND: Although survival of preterm infants has improved, prematurity remains the second-leading cause of death before 5 years of age in Romania. Data on the changing mortality of Romanian preterm infants born before 29 weeks of gestation have not been available. METHODS: We performed the present study to compare outcomes of infants of gestational age 25-28 weeks born in 2007-2010 (n=247) with those born in 2011-2014 (n=235). Data were analyzed from 3 tertiary neonatal intensive care centers...
September 1, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28857439/shprintzen-goldberg-syndrome-associated-with-first-cervical-vertebra-defects
#8
Tomohiro Saito, Takaya Nakane, Hideaki Yagasaki, Atsushi Naito, Kanji Sugita
No abstract text is available yet for this article.
August 31, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28856790/msh2-deletion-with-crebbp-and-kras-mutations-in-pediatric-high-hyperdiploid-acute-lymphoblastic-leukemia
#9
Jun-Ichi Ueyama, Mizuka Miki, Keisuke Okuno, Shohei Eto, Akira Shimada
No abstract text is available yet for this article.
August 30, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28856776/malnutrition-caused-by-unexpectedly-low-protein-concentration-in-breast-milk
#10
Yuya Nakano, Chizu Hirabayashi, Masahiko Murase, Katsumi Mizuno, Kazuo Itabashi
No abstract text is available yet for this article.
August 30, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28856764/polymicrobial-bloodstream-infection-in-an-immunocompetent-child
#11
Akane Ono, Hiroshi Yamaguchi, Yusuke Ito, Masashi Kasai
No abstract text is available yet for this article.
August 30, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28851072/association-of-zinc-and-copper-with-clinical-parameters-in-preterm-newborn
#12
Chiharu Kojima, Hiromichi Shoji, Ikeda Naho, Tomohiro Kitamura, Ken Hisata, Toshiaki Shimizu
BACKGROUND: As preterm infants are born at a time of rapid fetal growth, they are at the risk of deficiencies of essential nutrients for brain development, including zinc (Zn) and copper (Cu). This study aimed to evaluate the relationship between serum Cu or Zn levels and gestational age (GA), anthropometric parameters at birth in preterm infants. METHODS: This is a retrospective study of infants less than 35 weeks GA from January 2010 to August 2012. We corrected the data from medical records of 59 preterm infants at birth including GA, anthropometric parameters, serum levels of Cu and Zn...
August 29, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28846833/loss-of-surfacten-%C3%A2-during-bolus-administration-using-a-feeding-catheter
#13
Kazumichi Fujioka, Jumpei Kuroda, Keiji Yamana, Kazumoto Iijima, Ichiro Morioka
BACKGROUND: Surfactant replacement therapy is widely used for treating neonatal respiratory distress syndrome. However, insufficient evidence is available on the use of Surfacten(®) (S-TA). This study aimed to determine the inadvertent loss of S-TA during instillation via feeding catheters with different bore sizes. METHODS: In this bench-based study, we measured the weight of syringes and tubes before and after surfactant administration by using a high-accuracy balance, and determined the amount of S-TA lost in tubes...
August 28, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28833971/the-evaluation-of-the-therapeutic-outcomes-of-umbilical-hernia
#14
Makoto Hayashida, Takashi Shimozono, Satoru Meiri, Jun Kurogi, Naoto Yamashita, Toshinobu Ifuku, Yoshiko Yamamura, Etsuko Tanaka, Shigeki Ishii, Hidemi Shimonodan, Yuka Mihara, Keiichiro Kono, Keigo Nakatani, Toshihiro Nishiguchi
BACKGROUND: An adhesive strapping for umbilical hernia has been reevaluated as a promising treatment. We evaluated the influence of adhesive strapping on the outcome of umbilical hernia. METHODS: We retrospectively evaluated patients with umbilical hernia patients who were referred to our institution from April 2011 to December 2015. Patients who were treated with adhesive strapping were compared with an observation alone group. The adhesive strapping group was also sub-divided into two groups; the cure group and the treatment failure group...
August 18, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28833913/trends-of-urinary-beta-2-microglobulin-levels-and-bronchopulmonary-dysplasia-in-preterm-infants
#15
Yoshio Shima, Sakae Kumasaka, Shigeru Nishimaki
BACKGROUND: The developmental process of bronchopulmonary dysplasia is not identical between very preterm infants born small-for-gestational age and those born appropriate-for-gestational age. In this study, we compared the pattern of the inflammatory response in infants of each group, by measuring urinary beta-2-microglobulin as an alternative, concise, and less- invasive biomarker. METHODS: Urinary beta-2-microglobulin levels and clinical details were examined at birth and 4 weeks of age in 146 very preterm infants...
August 18, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28833908/regional-difference-of-infant-25ohd-levels-in-pilot-study-of-japan-environment-and-children-s-study
#16
Tadayuki Ayabe, Kiwako Yamamoto-Hanada, Hidetoshi Mezawa, Mizuho Konishi, Kazue Ishitsuka, Mayako Saito, Maki Fukami, Takehiro Michikawa, Shin Yamazaki, Ayako Senju, Koichi Kusuhara, Toshihiro Kawamoto, Masafumi Sanefuji, Kiyoko Kato, Masako Oda, Hiroshi Mitsubuchi, Takahiko Katoh, Yukifumi Monden, Nathan Mise, Fujio Kayama, Hirohisa Saito, Yukihiro Ohya
BACKGROUND: In recent years, a resurgence in the number of infants with vitamin D deficiency has been noted. In addition to seasonal differences in exposure to ultraviolet (UV) rays, regional differences in dietary habits and lifestyles may affect susceptibility to vitamin D deficiency. However, no studies have been conducted on infants in multiple regions of Japan to determine the extent of differences in vitamin D status. METHODS: The levels of 25-hydroxyvitamin D (25OHD) were measured by radioimmunoassay in 126 infants aged 2 to 4 years, who participated in the Pilot Study of the Japan Environment and Children's Study (JECS) by the Ministry of Environment of Japan...
August 18, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28815860/anxieties-felt-by-ccss-after-treatment-and-the-need-for-continued-support
#17
Naoko Iwai, Akira Shimada, Atsushi Iwai, Sonoe Yamaguchi, Hirokazu Tsukahara, Megumi Oda
BACKGROUND: Childhood cancer survivors (CCSs) and their family members continue to live in fear even after treatment is concluded due to concerns about late effects and recurrences. The consequent long-term psychological burden requires long-term follow-up suited to the anxieties and needs of CCSs, which is why we have conducted the present survey. METHODS: We conducted a questionnaire survey at medical facilities in the Chugoku and Shikoku regions of Japan with CCSs who had survived for at least 5 years following treatment, and their family members...
August 16, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28809080/congenital-complete-atrioventricular-block-with-pulmonary-hypertension
#18
Akiko Komori, Mamoru Ayusawa, Masataka Kato, Takahiro Nakamura, Shori Takahashi
No abstract text is available yet for this article.
August 14, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28802084/the-parameters-that-help-to-differentiate-biliary-atresia-from-other-diseases
#19
Makoto Hayashida, Toshiharu Matsuura, Yoshiaki Kinoshita, Genshiro Esumi, Koichiro Yoshimaru, Yusuke Yanagi, Yoshiaki Takahashi, Tomoaki Taguchi
BACKGROUND: The diagnosis of biliary atresia (BA) is still challenging. The aim of this study was to analyze the clinical features and parameters that contribute to a diagnosis of BA. METHODS: From January 2000 to December 2013, 37 patients who underwent operative cholangiography were evaluated retrospectively. The patients were divided into two groups: a BA group, and a group with other cholestatic diseases (non-BA group). The demographic data and preoperative liver function test results were analyzed...
August 12, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28802081/association-between-creativity-and-physical-fitness-in-primary-school-aged-children
#20
Pedro Ángel Latorre Román, Felipe García Pinillos, Antonio Pantoja Vallejo, Beatriz Berrios Aguayo
AIM: To analyse the relationship between creativity and physical fitness in elementary school children. METHOD: Data were collected from 308 primary school students in southern Spain, ranging in age from 8 to 12 years (M=9.72, SD=1.25). They performed a fitness test battery and the PIC-N questionnaire test was used to analyse creativity. RESULTS: Significant differences were found between sexes. Boys showed better physical fitness but there were no sex differences on creativity...
August 12, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
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