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Reports of Practical Oncology and Radiotherapy

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https://www.readbyqxmd.com/read/27920612/long-term-clinical-toxicity-of-radiation-therapy-in-prostate-cancer-patients-with-inflammatory-bowel-disease
#1
Matthew M Gestaut, Gregory P Swanson
AIM: The study's aim was to examine the clinical impact of radiation therapy (RT) on GI toxicity in Inflammatory Bowel Disease (IBD) patients. BACKGROUND: IBD has long been considered a risk factor for increased bowel toxicity from RT; however, minimal evidence exists on patients with prostate cancer (PC) and IBD. MATERIALS AND METHODS: The tumor registry was queried for patients with IBD and PC from the years 1990-2013. A retrospective review was conducted for patients who received RT...
January 2017: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/27920611/products-based-on-olive-oil-betaine-and-xylitol-in-the-post-radiotherapy-xerostomia
#2
Margarita Martín, Alicia Marín, Mario López, Olga Liñán, Felipe Alvarenga, David Büchser, Laura Cerezo
AIM: The objective of this study was determining if the use of products based in olive oil, betaine and xylitol are efficacious to decrease the impact of the dry mouth in the quality of life of the patients with xerostomia due to radiotherapy treatment. BACKGROUND: Following therapeutic irradiation of the head and neck, patients with profound xerostomia have complaints associated with oral dryness, speech, and taste. There is no strong evidence that any topical therapy is effective for relieving the symptom of dry mouth...
January 2017: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/27920610/volumetric-image-guided-highly-conformal-radiotherapy-of-the-prostate-bed-toxicity-analysis
#3
Gianluca Ingrosso, Alessandra Carosi, Daniela di Cristino, Elisabetta Ponti, Andrea Lancia, Alessandra Murgia, Claudia Bruni, Pasquale Morelli, Franca Pietrasanta, Riccardo Santoni
AIM: To evaluate toxicity of high conformal image-guided radiotherapy of the prostate bed. BACKGROUND: Radiotherapy of the prostate bed has a pivotal role in the post-operative and salvage settings, but few clinical data are available on the use of daily image guidance in combination with highly conformal techniques, and data on long-term results are lacking. MATERIALS AND METHODS: We analyzed 118 patients irradiated on the prostate bed using conformal plans processed with a micro-multileaf collimator, and daily checking treatment set-up with a cone-beam CT system...
January 2017: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/27843413/effectiveness-of-radiotherapy-for-metastatic-spinal-cord-compression-in-patients-with-short-life-expectancy
#4
Alexandra Giraldo, Sergi Benavente, Mónica Ramos, Ramona Vergés, Odimar Coronil, Lina Arbeláez, Xavier Maldonado, Manuel Altabas, Meritxell Mollà, Victoria Reyes, Begoña Navalpotro, Jordi Giralt
AIM: To analyze the effect of radiotherapy (RT) in patients with metastatic spinal cord compression (MSCC) and poor prognosis in our center. BACKGROUND: RT is an effective treatment for MSCC. MATERIALS AND METHODS: Prospective evaluation on patients with MSCC and limited survival (according to Rades' scale), and treated with single-dose 8 Gy RT (February 2013-August 2014). Pain, ambulatory status and sphincter control were recorded. Pain relief was evaluated following the International Bone Metastases Consensus Working Party Guidelines...
January 2017: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/27829820/simulation-of-positron-emitters-for-monitoring-of-dose-distribution-in-proton-therapy
#5
Mohsen Mashayekhi, Ali Asghar Mowlavi, Sayyed Bijan Jia
AIM: The purpose of this work was to estimate the dependency between the produced positron emitters and the proton dose distribution as well as the dependency between points of annihilation and the proton dose distribution. BACKGROUND: One important feature of proton therapy is that, through the non-elastic nuclear interaction of protons with the target nuclei such as (12)C, (14)N and (16)O, it produces a small number of positron-emitting radioisotopes along the beam-path...
January 2017: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/27829819/presenting-and-simulating-an-innovative-model-of-liver-phantom-and-applying-two-methods-for-dosimetry-of-it-in-neutron-radiation-therapy
#6
Seyed Alireza Mousavi Shirazi, Ali Pazirandeh, Gholamreza Jahanfarnia, Mitra Athari Allaf
AIM: A new model of liver phantom is defined, then this model is simulated by MCNPX code for dosimetry in neutron radiation therapy. Additionally, an analytical method is applied based on neutrons collisions and mathematical equations to estimate absorbed doses. Finally, the results obtained from two methods are compared to each other to justify the approach. BACKGROUND: The course of treatment by neutron radiation can be implemented to treat cancerous tissues, although this method has not yet been widespread...
January 2017: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/27818615/why-do-we-need-irradiation-of-internal-mammary-lymph-nodes-in-patients-with-breast-cancer-analysis-of-lymph-flow-and-radiotherapy-studies
#7
Novikov Sergey Nikolaevich, Kanaev Sergey Vasilevich
AIM: Using clinical data and results of lymphoscintigraphy to calculate probability of internal mammary lymph node (IMLN) invasion by breast cancer (BC). To evaluate clinical value of lymphoscintigraphy as the guide for irradiation of IMLN. METHODS: Using the data of eight published studies that analyzed lymph flow from primary BC (4541pts) after intra-peri-tumoral injection of nanosized 99mTc-colloids we determined probability of lymph-flow from internal-central and external BC to IMLN...
January 2017: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/27790075/practical-issues-regarding-angular-and-energy-response-in-in-vivo-intraoperative-electron-radiotherapy-dosimetry
#8
Juan López-Tarjuelo, Ana Bouché-Babiloni, Virginia Morillo-Macías, Agustín Santos-Serra, Carlos Ferrer-Albiach
AIM: To estimate angular response deviation of MOSFETs in the realm of intraoperative electron radiotherapy (IOERT), review their energy dependence, and propose unambiguous names for detector rotations. BACKGROUND: MOSFETs have been used in IOERT. Movement of the detector, namely rotations, can spoil results. MATERIALS AND METHODS: We propose yaw, pitch, and roll to name the three possible rotations in space, as these unequivocally name aircraft rotations...
January 2017: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/27790074/effects-of-siemens-tt-d-carbon-fiber-table-top-on-beam-attenuation-and-build-up-region-of-6%C3%A2-mv-photon-beam
#9
Asma Sheykhoo, Sara Abdollahi, Mohammad Hadi Hadizadeh Yazdi, Mahdi Ghorbani, Mohammad Mohammadi
AIM: This study deals with Monte Carlo simulations of the effects which the 550 TXT carbon fiber couch can have on the relevant parameters of a 6 MV clinical photon beam in three field sizes. BACKGROUND: According to the reports issued by the International Commission on Radiation Units and Measurements (ICRU), the calculated dose across a high gradient distribution should be within 2% of the relative dose, or within 0.2 cm of the isodose curve position in the target volume...
January 2017: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/27790073/dosimetric-influence-of-filtered-and-flattening-filter-free-photon-beam-on-rapid-arc-ra-radiotherapy-planning-in-case-of-cervix-carcinoma
#10
Lalit Kumar, Girigesh Yadav, Kothanda Raman Samuvel, Manindra Bhushan, Pawan Kumar, Mahammood Suhail, Manoj Pal
AIM: To investigate the dosimetric influence of filtered and flattening filter free (FFF) photon beam of 6 and 10 MV energies on cervix RA radiotherapy planning and to find possibilities to develop the clinically acceptable RA plans with FFFB photon beam and explore their potential benefits to cervix cancer patients. BACKGROUND: FFF photon beams enhances the treatment delivery by increased dose rate which results in shorter treatment time, this shorter treatment time reduces intrafraction motion and enhance comfort to the patients...
January 2017: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/27790072/dosimetric-influence-of-photon-beam-energy-and-number-of-arcs-on-volumetric-modulated-arc-therapy-in-carcinoma-cervix-a-planning-study
#11
Girigesh Yadav, Manindra Bhushan, Abhinav Dewan, Upasna Saxena, Lalit Kumar, Deepika Chauhan, Kothanda Raman, Swarupa Mitra, Mahammood Suhail
AIM: Aim of the present study was to compare the dosimetric impact of different photon beam energies and number of arcs in the treatment of carcinoma cervix. BACKGROUND: Carcinoma cervix is a common cancer in women worldwide with a high morbidity rate. Radiotherapy is used to treat such tumours. Volumetric Modulated Arc Therapy (VMAT) is considered superior to other techniques with multiple arcs and energies. MATERIALS AND METHODS: Twenty patients with carcinoma cervix underwent radiotherapy in a prospective observation study conducted at our institute...
January 2017: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/27721672/an-empirical-method-for-automatic-determination-of-maximum-number-of-segments-in-dmpo-based-imrt-for-head-and-neck-cases
#12
Vaitheeswaran Ranganathan, K Joseph Maria Das
AIM: An empirical scheme called "anatomy-guided segment counting (AGSC)" is proposed for automatic selection of maximum number of segments (NOS) for direct machine parameter optimization (DMPO). BACKGROUND: Direct machine parameter optimization (DMPO) requires the user to define the maximum number of segments (NOS) in order to proceed with an optimization process. Till date there is no established approach to arrive at an optimal and case-specific maximum NOS in DMPO, and this step is largely left to the planner's experience...
November 2016: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/27721671/prostate-intensity-modulated-radiotherapy-planning-in-seven-mouse-clicks-development-of-a-class-solution-for-cancer
#13
Maree Wood, Amara Fonseca, David Sampson, Andrew Kovendy, Justin Westhuyzen, Thomas Shakespeare, Kirsty Turnbull
AIM: The aim of the retrospective study was to develop a planning class solution for prostate intensity-modulated radiotherapy (IMRT) that achieved target and organs-at-risk (OAR) doses within acceptable departmental protocol criteria using the Monaco treatment planning system (Elekta-CMS Software, MO, USA). BACKGROUND: Advances in radiation therapy technology have led to a re-evaluation of work practices. Class solutions have the potential to produce highly conformal plans in a time-efficient manner...
November 2016: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/27721670/comprehensive-assessment-of-somnolence-syndrome-in-patients-undergoing-radiation-to-the-brain
#14
Ritika R Harjani, Janaki Manur Gururajachar, Umamaheswari Krishnaswamy
AIM: The aim of this prospective study was to assess Somnolence Syndrome (SS) in patients undergoing radiation to the brain. BACKGROUND: SS is one of the sequelae of radiation to the brain, which is observed within three months of radiation. This is a self-limiting condition and a failure to diagnose leads to unnecessary investigations. This study was undertaken to objectively and subjectively analyze the occurrence, clinical presentation and severity of SS. MATERIALS AND METHODS: Thirty-three patients receiving radiation to the brain were included in the study...
November 2016: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/27721669/asymptomatic-internal-carotid-artery-occlusion-after-gamma-knife-radiosurgery-for-pituitary-adenoma-report-of-two-cases-and-review-of-the-literature
#15
Giorgio Spatola, Laura Frosio, Marco Losa, Antonella Del Vecchio, Martina Piloni, Pietro Mortini
BACKGROUND: Gamma knife radiosurgery is an effective and safe treatment modality in the management of pituitary adenomas. Internal carotid occlusion is a rare but possible complication of Gamma Knife Radiosurgery for lesions within the cavernous sinus. AIM: To stress the importance of considering the Internal carotid artery as an organ at risk in cavernous sinus invading adenomas and reduce the dose delivered to this structure whenever possible. CASE DESCRIPTION: We report two cases of asymptomatic occlusion of the intracavernous segment of the internal carotid artery seven years after treatment in acromegalic patients...
November 2016: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/27708554/individually-optimized-stereotactic-radiotherapy-for-pancreatic-head-tumors-a-planning-feasibility-study
#16
Milly Buwenge, Savino Cilla, Alessandra Guido, Lucia Giaccherini, Gabriella Macchia, Francesco Deodato, Silvia Cammelli, Francesco Cellini, Gian C Mattiucci, Vincenzo Valentini, Markus Stock, Alessio G Morganti
AIM: Aim of this study was to perform a planning feasibility analysis of a 3-level dose prescription using an IMRT-SIB technique. BACKGROUND: Radiation therapy of locally advanced pancreatic cancer should administer a minimum dose to the duodenum and a very high dose to the vascular infiltration areas to improve the possibility of a radical resection. MATERIALS AND METHODS: Fifteen patients with pancreatic head adenocarcinoma and vascular involvement were included...
November 2016: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/27698593/hypofractionated-accelerated-radiotherapy-in-t1-3-n0-cancer-of-the-larynx-a-prospective-cohort-study-with-historical-controls
#17
Zbigniew Szutkowski, Andrzej Kawecki, Andrzej Jarząbski, Zofia Laskus, Romuald Krajewski, Wojciech Michalski, Paweł Kukołowicz
AIM: The goal of this prospective study was to assess the effectiveness of a hypofractionated accelerated regime in treatment of the larynx cancer. BACKGROUND: Multiple radiotherapy delivery regimes are used for treatment of the larynx cancer. Hypofractionated regimes could provide similar results with reduced use of radiotherapy facilities. MATERIAL AND METHODS: 223 patients with squamous cell carcinoma of the upper or middle larynx have been treated with 63 Gy delivered in 28 fractions of 2...
November 2016: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/27698592/treatment-planning-study-of-volumetric-modulated-arc-therapy-and-three-dimensional-field-in-field-techniques-for-left-chest-wall-cancers-with-regional-lymph-nodes
#18
Heping Xu, Gillian Hatcher
AIM: This study aims to investigate whether there are dosimetric advantages to using VMAT (Volumetric Modulated Arc Therapy) for left-sided chest-wall patients over the three-dimensional conformal field-in-field (FinF) technique. BACKGROUND: There is a lack of dosimetric studies dedicated for chest-wall patients. Potential dosimetric advantage could be obtained using VMAT due to complex geometry of PTVs (Planning Target Volumes) and OARs (Organs at Risk) in chest-wall and lymph nodes...
November 2016: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/27698591/spiderplan-a-tool-to-support-decision-making-in-radiation-therapy-treatment-plan-assessment
#19
Tiago Ventura, Maria do Carmo Lopes, Brigida Costa Ferreira, Leila Khouri
AIM: In this work, a graphical method for radiotherapy treatment plan assessment and comparison, named SPIDERplan, is proposed. It aims to support plan approval allowing independent and consistent comparisons of different treatment techniques, algorithms or treatment planning systems. BACKGROUND: Optimized plans from modern radiotherapy are not easy to evaluate and compare because of their inherent multicriterial nature. The clinical decision on the best treatment plan is mostly based on subjective options...
November 2016: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/27698590/dosimetric-feasibility-of-an-off-breast-isocenter-technique-for-whole-breast-cancer-radiotherapy
#20
Juan-Francisco Calvo-Ortega, Sandra Moragues, Miquel Pozo, Joan Casals
AIM: To investigate the viability of placing the treatment isocenter at the patient midline for breast cancer radiotherapy in order to avoid the risk of collisions during image-guided setup and treatment delivery. BACKGROUND: The use of kilovoltage orthogonal setup images has spread in last years in breast radiotherapy. There is a potential risk of an imaging system-patient collision when the isocenter is laterally placed. MATERIALS AND METHODS: Twenty IMRT plans designed by placing the isocenter within the breast volume ("plan_ref"), were retrospectively replanned by shifting the isocenter at the patient's midline ("plan_off-breast")...
November 2016: Reports of Practical Oncology and Radiotherapy
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