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Catheterization and Cardiovascular Interventions

Jing-Jing Xu, Ying Song, Ping Jiang, Zhan Gao, Jian-Xin Li, Jue Chen, Yue-Jin Yang, Run-Lin Gao, Bo Xu, Jin-Qing Yuan
OBJECTIVES: To evaluate the effect of prior stroke on long-term outcomes in patients undergoing percutaneous coronary interventions (PCI). BACKGROUND: Patients with coronary heart disease (CHD) and prior stroke history have more serious clinical and angiographic conditions, which make the choice of treatment strategy complex. METHODS: A total of 10,724 consecutive patients who underwent PCI from January 2013 to December 2013 were enrolled...
November 13, 2018: Catheterization and Cardiovascular Interventions
Junhua Ge, Jian Li, Bingzi Dong, Xianfeng Ning, Bo Hou
OBJECTIVES: We aimed to investigate the determinants of thrombus burden (TB) and the impact of thrombus aspiration (TA) on outcome in young adults with ST segment elevation myocardial infarction (STEMI). BACKGROUND: The determinants of TB in young STEMI patients are not fully understood now. METHODS: The 182 young (age ≤ 45 years) STEMI patients, who underwent coronary angiography and percutaneous coronary intervention (PCI) in our hospital from January 2013 to September 2016, were included...
November 12, 2018: Catheterization and Cardiovascular Interventions
Kothandam Sivakumar, Bijesh Viswambaran, Sudipta Bhattacharjya
OBJECTIVES: To study the feasibility of closure of large atrial septal defects (ASDs) using occluder devices >38 mm and assess the midterm complications. BACKGROUND: Feasibility and safety of large occluders >38 mm and their follow-up are largely unknown. METHODS: All patients with ASDs closed using devices >38 mm were retrospectively analyzed. Since outcome of patients receiving 40 mm devices were known before, patients receiving 40 mm devices were compared with those receiving 42-46 mm devices on demographic, hemodynamic parameters and procedural characteristics...
November 12, 2018: Catheterization and Cardiovascular Interventions
Andrew B Ho, Markku Kaarne, Michael Mullen, Nicholas Hayes
Tricuspid regurgitation in the context of hypoplastic left heart syndrome (HLHS) carries a significant burden of both mortality and morbidity. We report successful hybrid trans-atrial implantation of an Edwards Sapien XT valve into a dysfunctional bioprosthetic valve in the tricuspid position of a 9-year-old patient with HLHS. There was an immediate fall in the Fontan pressures combined with significant clinical improvement and the valve continues to function well nearly 3 years post implant. To the best of our knowledge, this is the first described implantation of a transcatheter valve in this specific position and anatomy...
November 12, 2018: Catheterization and Cardiovascular Interventions
Giorgio Quadri, Enrico Cerrato, Cristina Rolfo, Ferdinando Varbella
A young woman admitted with a diagnosis of NSTE-ACS underwent coronary angiography which showed LAD spontaneous coronary artery dissection treated with magnesium-made bioresorbable scaffold. We report 1-year angiographic and OCT findings.
November 12, 2018: Catheterization and Cardiovascular Interventions
Brian H Morray, Thomas K Jones, James Y Coe, Roland Gitter, Jose Zunzunegui Martinez, Daniel R Turner, Robert G Gray, Te-Hsin Lung, Darren P Berman, Daniel S Levi
OBJECTIVES: This study describes procedural and 1-year outcomes of the 16 mm Melody PB1016 valve in patients with dysfunctional RVOT conduits. BACKGROUND: The Melody PB1016 is a standard Melody valve produced from a 16 mm bovine jugular vein and is intended for deployment up to 20 mm. METHODS: This is a prospective, non-randomized, multicenter study of the procedural and short-term outcomes of Melody PB1016 TPV replacement within dysfunctional RVOT conduits...
November 12, 2018: Catheterization and Cardiovascular Interventions
Patrick J Goleski, Kenta Nakamura, Emily Liebeskind, Adam C Salisbury, J Aaron Grantham, James M McCabe, William L Lombardi
OBJECTIVES: To determine whether a variation of an abandoned antegrade percutaneous coronary intervention (PCI) technique, termed subintimal tracking and reentry (STAR), could be a safe and effective strategy to contend with complex coronary chronic total occlusions (CTO) when other strategies fail. BACKGROUND: Complex CTOs require advanced techniques such as the retrograde approach, which is associated with higher complication rates than antegrade strategies. METHODS: The medical records of 32 consecutive patients who underwent deferred stenting following STAR (DSS) between January 2015 and May 2017 at a high-volume referral center were retrospectively reviewed...
November 9, 2018: Catheterization and Cardiovascular Interventions
Najibullah Habib, Bakhtawar K Mahmoodi, Maarten J Suttorp, Johannes C Kelder, Selma C Tromp, Uday Sonker, Jan Van der Heyden
AIMS: To identify risk factors for composite outcome of mortality, stroke or myocardial infarction in patients with severe carotid stenosis undergoing staged carotid artery stenting (CAS) with subsequent cardiac surgery. METHODS AND RESULTS: In this prospective observational study, we enrolled 643 consecutive patients with both symptomatic (i.e., with history of stroke) and asymptomatic severe carotid artery disease, who required cardiac surgery. Generally, cardiac surgery was planned 30 days after the CAS procedure...
November 9, 2018: Catheterization and Cardiovascular Interventions
Christian Butter, Hidehiro Kaneko, Grit Tambor, Masahiko Hara, Michael Neuss, Frank Hoelschermann
OBJECTIVES: Novel automated computed tomography (CT) software (Valve ASSIST 2) has been developed for transcatheter aortic valve implantation (TAVI), which not only provides three-dimensional (3D) reconstruction of multidetector (MD) CT images, but also enables intraprocedural real-time fusion of fluoroscopic and MDCT images. We aimed to clarify the reproducibility and accuracy of this software in the aortic annulus assessment and verify the potential of intraprocedural integrated MDCT imaging for TAVI...
November 8, 2018: Catheterization and Cardiovascular Interventions
Roberto Spina, Omar Khalique, Susheel Kodali, Vinayak N Bapat
Transcatheter aortic valve replacement (TAVR) is not currently approved for pure native valve aortic incompetence, and is typically performed on a compassionate basis in selected patients who are at high risk for conventional surgery. We describe the first use of TAVR to treat iatrogenic severe acute pure aortic incompetence following mitral valve surgery. A 71-year-old gentleman developed life-threatening acute aortic regurgitation (AR) within hours of a very challenging fifth open heart mitral valve replacement...
November 8, 2018: Catheterization and Cardiovascular Interventions
Shabana Shahanavaz, Toby Rockefeller, Ramzi Nicolas, David Balzer
Transcatheter pulmonary valve replacement (TPVR) is now common practice in patients with significant pulmonary regurgitation (PR), stenosis (PS), or mixed pulmonary valve disease. While the Melody valve (Medtronic, Inc.) and its delivery system were specifically designed for use in the right ventricular outflow tract (RVOT), Sapien valves (XT and S3, Edwards Lifesciences, Inc.) and their delivery systems (Novaflex and Commander) were not. As a result, placement of Sapien valves in the RVOT can be challenging secondary to the stiffness of the current delivery system...
November 8, 2018: Catheterization and Cardiovascular Interventions
Tomo Ando, Oluwole Adegbala, Pedro A Villablanca, Alexandros Briasoulis, Hisato Takagi, Cindy L Grines, Theodore Schreiber, Tamim Nazif, Susheel Kodali, Luis Afonso
OBJECTIVES: To assess the in-hospital outcomes of transcatheter aortic valve replacement (TAVR) vs. surgical aortic valve replacement (SAVR) in non-teaching hospitals. BACKGROUND: TAVR has become widely available in the United States. However, the comparative outcomes of TAVR vs. SAVR in non-teaching hospitals are largely under explored. METHODS: We queried the Nationwide Inpatient Sample database from 2011 to September 2015 to identify those who were 50 years or above and underwent either trans-arterial TAVR or SAVR at non-teaching hospital...
November 8, 2018: Catheterization and Cardiovascular Interventions
Atsushi Sakaoka, Serge D Rousselle, Hitomi Hagiwara, Armando Tellez, Brad Hubbard, Kenichi Sakakura
OBJECTIVES: We aimed to investigate the safety of radiofrequency (RF)-renal denervation (RDN) on branch renal arteries (RAs) in a porcine model. BACKGROUND: The efficacy of RF-RDN was enhanced by treatment of the branch RA, in addition to the main RA. However, there are concerns regarding the safety of RF-RDN on branch RA because of their smaller diameter and proximity to the kidney. METHODS: RF was delivered to 24 RA from 12 swine. A total of 8 RA from 4 swine were untreated...
November 8, 2018: Catheterization and Cardiovascular Interventions
Babikir Kheiri, Mohammed Osman, Ahmed Abdalla, Tarek Haykal, Pranay V Pandrangi, Adam Chahine, Sahar Ahmed, Khansa Osman, Ghassan Bachuwa, Mustafa Hassan, Deepak L Bhatt
OBJECTIVES: This study aimed to evaluate the efficacy and safety of personalized genotype-guided selection of antiplatelet therapy versus standard of care in patients undergoing percutaneous coronary intervention (PCI). BACKGROUND: Clopidogrel is the most frequently used P2Y12 receptor antagonist in patients with coronary artery disease. However, genetic variations of clopidogrel are associated with inter-individual response variability which could limit its efficacy...
November 7, 2018: Catheterization and Cardiovascular Interventions
Cameron Dowling, Sami Firoozi, Niamh Doyle, Daniel J Blackman, Christopher J Malkin, Michael S Cunnington, Smriti Saraf, Mamta H Buch, Richard Levy, Saqib Chowdhary, Mark S Spence, Ganesh Manoharan, Colum G Owens, Paul F Brennan, David Roberts, Ranjit More, Andrew Wiper, Hesham K Abdelaziz, Darren Mylotte, Antoinette Neylon, Niamh Martin, Federico Mercanti, Stephen Dorman, Vasileios Panoulas, Miles Dalby, Mavin N Kashyap, Tito Kabir, Jan Kovac, Kosmas Kontoprias, Iqbal S Malik, Mikhail W Ghada, Sayan Sen, Neil Ruparelia, Ozan M Demir, Angela Frame, Neal G Uren, Richard Anderson, Thirumaran Rajathurai, Luke Tapp, Lauren Deegan, Ever Grech, Ian Hall, Melanie Neville, Rajiv Rampat, David Hildick-Smith, Michael Mullen, Simon Kennon, Pavan Chandrala, Sagar Doshi, Stephen J Brecker
OBJECTIVES: The UK & Ireland Implanters' registry is a multicenter registry which reports on real-world experience with novel transcatheter heart valves. BACKGROUND: The 34 mm Evolut R transcatheter aortic valve is a self-expanding and fully recapturable transcatheter aortic valve, designed to treat patients with a large aortic annulus. METHODS: Between January 2017 and April 2018, clinical, procedural and 30-day outcome data were prospectively collected from all patients receiving the 34 mm Evolut R valve across 17 participating centers in the United Kingdom and Ireland...
November 5, 2018: Catheterization and Cardiovascular Interventions
Prasad Gunasekaran, Dusan Stanojevic, Taylor Drees, John Fritzlen, Megan Haghnegahdar, Matthew McCullough, Rajat Barua, Ashwani Mehta, Eric Hockstad, Mark Wiley, Matthew Earnest, Peter Tadros, Randall Genton, Kamal Gupta
OBJECTIVES: To assess the prognostic significance of high vs. low grade coronary artery ectasia (CAE) and the impact of antithrombotic or anticoagulant therapy on adverse cardiac outcomes. BACKGROUND: There is paucity of knowledge on the impact of angiographic characteristics in CAE or that of antithrombotic or anticoagulant therapy on outcomes. METHODS AND RESULTS: In this retrospective study, we reviewed angiograms and medical records of all cases of confirmed CAE (2001-2011)...
November 4, 2018: Catheterization and Cardiovascular Interventions
Sammy Elmariah, Sunil V Rao, Cindy L Grines, Kirk N Garratt, Ronald P Caputo, Timothy D Henry, Srihari S Naidu, Narinder Bhalla, Bill Gagliardi, John Venditto
No abstract text is available yet for this article.
November 4, 2018: Catheterization and Cardiovascular Interventions
Hitinder S Gurm, Kreton Mavromatis, Barry Bertolet, Dean J Kereiakes, Amit P Amin, Atman P Shah, George S Hanzel, Siddhartha Rao, Joseph L Thomas, Gautam Kumar
OBJECTIVE: To evaluate contrast media (CM) volume (CMV) saved using the DyeVert™ Plus Contrast Reduction System (DyeVert Plus System, Osprey Medical) in patients undergoing diagnostic coronary angiogram (CAG) and/or percutaneous coronary interventional (PCI) procedures performed with manual injections. BACKGROUND: Current guidelines advocate for monitoring and minimization of the total volume of CM in chronic kidney disease (CKD) patients undergoing invasive cardiac procedures...
November 4, 2018: Catheterization and Cardiovascular Interventions
Nicholas Isom, Reza Masoomi, Axel Thors, Matthew Bunte, Anand Prasad, Kirk Hance, Kamal Gupta
BACKGROUND/OBJECTIVES: Orbital atherectomy (OA) is routinely being used for plaque modification to facilitate percutaneous revascularization in patients with peripheral arterial disease (PAD) and arterial calcification. Guidewire fracture (GWF) during OA, though anecdotally described, has not been studied in a systematic manner. We conducted a review of the Manufacturer and User Facility Device Experience (MAUDE) database to study the reports of wire fracture and its management and consequences...
November 1, 2018: Catheterization and Cardiovascular Interventions
Brandon D Morrical, Joseph A Dearani, Allison K Cabalka
We present a case of a 7-year-old boy with a history of multiple mitral valve interventions and subsequent Melody valve placement in the mitral position, who presented with acute mitral stenosis due to complete fracture of the Melody stent. He was born early with severe mitral and tricuspid insufficiency due to valvular dysplasia, and ended up with 4 sternotomies before the age of 2 due to mitral valve dysfunction and recurrent prosthetic valve thrombosis. He then developed mixed stenosis and regurgitation at age 6, and to avoid another sternotomy, valve-in-valve therapy with off-label use of a 20-mm Melody valve was done with hybrid procedure via trans-apical approach...
October 31, 2018: Catheterization and Cardiovascular Interventions
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