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Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research

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https://www.readbyqxmd.com/read/30314628/systematic-review-and-network-meta-analysis-of-treatments-for-chemotherapy-naive-patients-with-asymptomatic-mildly-symptomatic-metastatic-castration-resistant-prostate-cancer
#1
REVIEW
Rachael McCool, Kelly Fleetwood, Julie Glanville, Mick Arber, Howard Goodall, Shevani Naidoo
OBJECTIVES: To estimate the relative effectiveness of enzalutamide in chemotherapy-naive metastatic castration-resistant prostate cancer by conducting a systematic literature review and a network meta-analysis (NMA). METHODS: A systematic literature review identified randomized controlled trials comparing enzalutamide, abiraterone/prednisone, radium-223, sipuleucel-T, or docetaxel with each other or placebo in chemotherapy-naive or mixed populations (with and without prior chemotherapy) with asymptomatic/mildly symptomatic metastatic castration-resistant prostate cancer...
October 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/30314627/model-comparisons-of-the-effectiveness-and-cost-effectiveness-of-vaccination-a-systematic-review-of-the-literature
#2
REVIEW
Mélanie Drolet, Élodie Bénard, Mark Jit, Raymond Hutubessy, Marc Brisson
OBJECTIVES: To describe all published articles that have conducted comparisons of model-based effectiveness and cost-effectiveness results in the field of vaccination. Specific objectives were to 1) describe the methodologies used and 2) identify the strengths and limitations of the studies. METHODS: We systematically searched MEDLINE and Embase databases for studies that compared predictions of effectiveness and cost-effectiveness of vaccination of two or more mathematical models...
October 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/30314626/test-retest-reliability-of-eq-5d-5l-valuation-techniques-the-composite-time-trade-off-and-discrete-choice-experiments
#3
Fredrick Dermawan Purba, Joke A M Hunfeld, Reinier Timman, Aulia Iskandarsyah, Titi Sahidah Fitriana, Sawitri S Sadarjoen, Jan Passchier, Jan J V Busschbach
OBJECTIVES: To explore the test-retest reliability of the composite time trade-off (C-TTO) and discrete choice experiment (DCE) used in the Indonesian five-level EuroQol five-dimensional questionnaire (EQ-5D-5L) valuation study. METHODS: A representative sample aged 17 years and older was recruited from the Indonesian general population by stratified quota sampling with respect to residence, sex, and age. Trained interviewers conducted computer-assisted face-to-face interviews using the EuroQol valuation technology...
October 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/30314625/estimating-a-dutch-value-set-for-the-pediatric-preference-based-chu9d-using-a-discrete-choice-experiment-with-duration
#4
Donna Rowen, Brendan Mulhern, Katherine Stevens, Jan Hendrik Vermaire
OBJECTIVE: This article presents the development of the Dutch value set for the Child Health Utility 9D, a pediatric preference-based measure of quality of life that can be used to generate quality-adjusted life-years. METHODS: A large online survey was conducted using a discrete choice experiment including a duration attribute with adult members of the Netherlands general population (N = 1276) who were representative in terms of age, gender, marital status, employment, education, and region...
October 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/30314624/accuracy-of-linking-vr-12-and-promis-global-health-scores-in-clinical-practice
#5
Brittany R Lapin, Tyler G Kinzy, Nicolas R Thompson, Ajit Krishnaney, Irene L Katzan
OBJECTIVES: To examine the accuracy of general health cross-walk tables in a clinical sample of patients with spine disorders. Published tables (Schalet BD, Rothrock NE, Hays RD, et al. Linking physical and mental health summary scores from the Veterans RAND 12-Item Health Survey (VR-12) to the PROMIS(®) Global Health Scale. J Gen Intern Med 2015;30:1524-30) link scores from the Veterans RAND 12-Item Health Survey (VR-12) to the 10-Item Patient-Reported Outcome Measurement Information System (PROMIS), a global health scale metric for both mental (GMH) and physical (GPH) summary scores...
October 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/30314623/french-patients-with-hepatitis-c-treated-with-direct-acting-antiviral-combinations-the-effect-on-patient-reported-outcomes
#6
Patrice Cacoub, Marc Bourliere, Tarik Asselah, Victor De Ledinghen, Philippe Mathurin, Christophe Hézode, Linda Henry, Maria Stepanova, Zobair M Younossi
BACKGROUND: In addition to high efficacy, new anti-hepatitis C virus (HCV) regimens improve patient-reported outcomes (PROs), which must be considered by policymakers in different countries when deciding upon treatment coverage. OBJECTIVE: To assess PROs of French patients with HCV treated with different antiviral regimens. METHODS: French patients with HCV from 11 clinical trials were included. PROs were measured before, during, and after treatment (Short Form-36 version 2, Functional Assessment of Chronic Illness Therapy-Fatigue, Chronic Liver Disease Questionnaire-HCV, and Work Productivity and Activity Index: Specific Health Problem)...
October 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/30314622/does-selecting-covariates-using-factor-analysis-in-mapping-algorithms-improve-predictive-accuracy-a-case-of-predicting-eq-5d-5l-and-sf-6d-utilities-from-the-women-s-health-questionnaire
#7
Billingsley Kaambwa, Caroline Smith, Sheryl de Lacey, Julie Ratcliffe
BACKGROUND: In addition to theoretical justifications, many statistical methods have been used for selecting covariates to include in algorithms mapping nonutility measures onto utilities. However, it is not clear whether using exploratory factor analysis (EFA) as one such method improves the predictive ability of these algorithms. OBJECTIVE: This question is addressed within the context of mapping a non-utility-based outcome, the core 23-item Women's Health Questionnaire (WHQ-23), onto two utility instruments: five-level EuroQol five-dimensional questionnaire (EQ-5D-5L) and the six-dimensional health state short form (derived from short form 36 health survey) (SF-6D)...
October 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/30314621/development-of-a-patient-reported-outcome-measure-for-geriatric-care-the-older-persons-and-informal-caregivers-survey-short-form
#8
Angelina M M Santoso, Jennifer E Lutomski, Cynthia S Hofman, Silke F Metzelthin, Jeanet W Blom, Philip J van der Wees, Marcel G M Olde Rikkert, René J F Melis
BACKGROUND: The Older Persons and Informal Caregivers Minimum Data Set (TOPICS-MDS) is a standardized data set that was developed to evaluate the quality of multidimensional geriatric care. There is an inherent need to reduce the number of TOPICS-MDS survey items to core outcomes to allow it to be more easily applied as a patient-reported outcome measure in clinical settings. OBJECTIVES: To create a TOPICS-short form (TOPICS-SF) and examine its validity. METHODS: Data in the TOPICS-MDS from persons aged 65 years and older in the Netherlands were used for the following analyses...
October 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/30314620/assessing-rationality-in-discrete-choice-experiments-in-health-an-investigation-into-the-use-of-dominance-tests
#9
Tommi Tervonen, Tabea Schmidt-Ott, Kevin Marsh, John F P Bridges, Matthew Quaife, Ellen Janssen
BACKGROUND: Dominance tests are often applied to test for the rationality in the choice behavior of participants in discrete choice experiments (DCEs). OBJECTIVES: To examine how dominance tests have been implemented in recent DCE applications in health and discuss their theoretical and empirical interpretation. METHODS: Health-related DCEs published in 2015 were reviewed for the inclusion of tests on choice behavior. For studies that implemented a dominance test, information on application and interpretation of the test was extracted...
October 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/30314619/association-between-higher-generic-drug-use-and-medicare-part-d-star-ratings-an-observational-analysis
#10
Natalie Hohmann, Richard Hansen, Kimberly B Garza, Ilene Harris, Zippora Kiptanui, Jingjing Qian
BACKGROUND: Increasing generic drug use, due to potential for cost savings and drug access, is a viable consideration for Medicare prescription drug plans to achieve high star ratings and improve quality of plan offerings for Medicare beneficiaries. OBJECTIVE: To examine the association between contract-level proportion of generic drugs dispensed (pGDD) and Medicare Part D star ratings. METHODS: This was a retrospective study of linked 2011 Medicare Part D star rating data with contract-level pGDD data...
October 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/30314618/a-generic-model-for-follicular-lymphoma-predicting-cost-life-expectancy-and-quality-adjusted-life-year-using-uk-population-based-observational-data
#11
Han-I Wang, Eve Roman, Simon Crouch, Eline Aas, Cathy Burton, Russell Patmore, Alexandra Smith
OBJECTIVES: To use real-world data to develop a flexible generic decision model to predict cost, life expectancy, and quality-adjusted life-years (QALYs) for follicular lymphoma (FL) in the general patient population. METHODS: All patients newly diagnosed with FL in the UK's population-based Haematological Malignancy Research Network (www.hmrn.org) between 2004 and 2011 were followed until 2015 (N = 740). Treatment pathways, QALYs, and costs were incorporated into a discrete event simulation to reflect patient heterogeneity, including age and disease management...
October 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/30314617/focused-ultrasound-thalamotomy-and-other-interventions-for-medication-refractory-essential-tremor-an-indirect-comparison-of-short-term-impact-on-health-related-quality-of-life
#12
REVIEW
Bryony E Langford, Christian J A Ridley, Rebecca C Beale, Sophie C L Caseby, William J Marsh, Lance Richard
BACKGROUND: Up to 50% of essential tremor patients are refractory to medication and require alternative treatment to achieve tremor relief. This study aimed to identify and analyze evidence supporting the use of the emerging magnetic resonance-guided focused ultrasound (MRgFUS) compared to alternative stimulatory and ablative interventions for the treatment of medication-refractory essential tremor: radiofrequency thalamotomy, unilateral deep brain stimulation (DBS), and stereotactic radiosurgery...
October 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/30314616/researchers-patients-and-stakeholders-evaluating-comparative-effectiveness-research-a-mixed-methods-study-of-the-pcori-reviewer-experience
#13
Laura P Forsythe, Lori B Frank, Rachel Hemphill, A Tsahai Tafari, Victoria Szydlowski, Michael Lauer, Christine Goertz, Steven Clauser
OBJECTIVES: The Patient-Centered Outcomes Research Institute (PCORI) includes patients and stakeholders alongside scientists in reviewing research applications using unique review criteria including patient-centeredness and patient and/or stakeholder engagement. To support extension of this unique collaborative model to other funders, information from the reviewers on the review process is needed to understand how scientists and nonscientists evaluate research proposals together. Thus, this study aimed to describe reviewers' perspectives of the interactions during the in-person review panel; to examine the value and challenges of including scientists, patients, and stakeholders together; and to understand the perceived importance of PCORI's review criteria...
October 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/30314615/unique-review-criteria-and-patient-and-stakeholder-reviewers-analysis-of-pcori-s-approach-to-research-funding
#14
Laura P Forsythe, Lori B Frank, A Tsahai Tafari, Sarah S Cohen, Michael Lauer, Steven Clauser, Christine Goertz, Suzanne Schrandt
OBJECTIVE: The Patient-Centered Outcomes Research Institute (PCORI) uses a unique approach to Merit Review that includes patients and stakeholders as reviewers with scientists, and includes unique review criteria (patient-centeredness and active engagement of end users in the research). This study assessed the extent to which different reviewer types influence review scores and funding outcomes, the emphasis placed on technical merit compared to other criteria by a multistakeholder panel, and the impact of the in-person discussion on agreement among different reviewer types...
October 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/30314614/vaccination-programs-economic-and-leadership-considerations
#15
EDITORIAL
Kenneth Y Hartigan-Go
No abstract text is available yet for this article.
October 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/30314613/economic-analysis-of-vaccination-programs
#16
REVIEW
Josephine Mauskopf, Baudouin Standaert, Mark P Connolly, Anthony J Culyer, Louis P Garrison, Raymond Hutubessy, Mark Jit, Richard Pitman, Paul Revill, Johan L Severens
This report provides recommendations for budget holders and decision makers in high-, middle, and low-income countries requiring economic analyses of new vaccination programs to allocate scarce resources given budget constraints. ISPOR's Economic Evaluation of Vaccines Designed to Prevent Infectious Disease: Good Practices Task Force wrote guidelines for three analytic methods and solicited comments on them from external reviewers. Cost-effectiveness analyses use decision-analytic models to estimate cumulative changes in resource use, costs, and changes in quality- or disability-adjusted life-years attributable to changes in disease outcomes...
October 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/30224119/correction
#17
(no author information available yet)
No abstract text is available yet for this article.
September 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/30224118/quality-adjusted-life-years-without-constant-proportionality
#18
Benjamin M Craig, Kim Rand, Henry Bailey, Peep F M Stalmeier
BACKGROUND: A quality-adjusted life-year is a common unit of measurement in health valuation. Under its constant proportionality assumption, the value of a quality-adjusted life span is defined as the product of preference weight and life span. OBJECTIVES: To empirically identify an alternative functional relationship between life span and value by relaxing the constant proportionality assumption. METHODS: Using an online survey, 5367 respondents completed 30 to 40 paired comparisons where each involved a choice between two health outcomes: one with a longer life span and health problems (five-level EuroQol five-dimensional questionnaire) and the other with a shorter life span and no problems (time trade-off pair)...
September 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/30224117/evaluating-the-content-validity-of-four-performance-outcome-measures-in-patients-with-elective-hip-replacements-and-hip-fractures
#19
Rachel Ballinger, Cicely Kerr, Fiona Mowbray, Elizabeth Nicole Bush
OBJECTIVES: To assess the content validity of performance outcome (PerfO) measures for use with patients undergoing hip fracture (HF) surgery and elective total hip replacement (eTHR). METHODS: This study was a substudy of a broader evaluation of measurement properties of PerfO measures. The PerfO measures assessed were timed up and go (TUG), four-step stair climb (4SC), long stair climb (LSC), and repeated chair stand (RCS). For this substudy, HF and eTHR participants were interviewed to evaluate the relevance and difficulty of each PerfO measure...
September 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/30224116/evaluation-of-the-measurement-properties-of-four-performance-outcome-measures-in-patients-with-elective-hip-replacements-elective-knee-replacements-or-hip-fractures
#20
Helen Doll, Brittany Gentile, Elizabeth Nicole Bush, Rachel Ballinger
OBJECTIVES: To evaluate the measurement properties of four performance outcome (PerfO) measures (timed up and go, four-step stair climb, long stair climb, and repeated chair stand) in three patient populations(elective total hip replacement [eTHR], elective total knee replacement [eTKR], and hip fracture [HF]). METHODS: A cross-sectional and longitudinal design was used to assess the PerfO measurement properties using the US Food and Drug Administration guidance for industry around patient-reported outcome measures to support labeling claims...
September 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
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