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Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology

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https://www.readbyqxmd.com/read/28108550/cardiac-resynchronization-therapy-in-adults-with-congenital-heart-disease
#1
Zeliha Koyak, Joris R de Groot, Ahmed Krimly, Tara M Mackay, Berto J Bouma, Candice K Silversides, Erwin N Oechslin, Ulas Hoke, Lieselot van Erven, Werner Budts, Isabelle C Van Gelder, Barbara J M Mulder, Louise Harris
AIMS: In adults with congenital heart disease (CHD) heart failure is one of the leading causes of morbidity and mortality but experience with and reported outcome of cardiac resynchronization therapy (CRT) is limited. We investigated the efficacy of CRT in adults with CHD. METHODS AND RESULTS: This was a retrospective study including 48 adults with CHD who received CRT since 2003 in four tertiary referral centres. Responders were defined as patients who showed improvement in NYHA functional class and/or systemic ventricular ejection fraction by at least one category...
January 20, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28108549/relation-of-renal-dysfunction-with-incident-atrial-fibrillation-and-cardiovascular-morbidity-and-mortality-the-prevend-study
#2
Ernaldo G Marcos, Bastiaan Geelhoed, Pim Van Der Harst, Stefan J L Bakker, Ron T Gansevoort, Hans L Hillege, Isabelle C Van Gelder, Michiel Rienstra
AIMS: Renal dysfunction is a risk factor for cardiovascular disease, including atrial fibrillation (AF) and mortality. However, the exact pathobiology linking different renal dysfunction measures, such as albumin excretion or glomerular filtration rate (GFR), to cardiovascular- and AF risk are unclear. In this study, we investigated the association of several renal function measures and incident AF, and whether the relation between renal measures and outcomes is modified by AF. METHODS AND RESULTS: We examined 8265 individuals (age 49 ± 13 years, 50% women) included in the PREVEND study...
January 20, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28108548/the-effect-of-left-ventricular-pacing-on-transmural-activation-delay-in-myopathic-human-hearts
#3
Andreu Porta-Sánchez, Paul Angaran, Stéphane Massé, Krishnakumar Nair, Talha Farid, Karthikeyan Umapathy, John Asta, Sigfus Gizurarson, Kumaraswamy Nanthakumar
AIMS: Left ventricular (LV) epicardial pacing (LVEpiP) in human myopathic hearts does not decrease global epicardial activation delay compared with right ventricular (RV) endocardial pacing (RVEndoP); however, the effect on transmural activation delay has not been evaluated. To characterize the transmural electrical activation delay in human myopathic hearts during RVEndoP and LVEpiP compared with global epicardial activation delay. METHODS AND RESULTS: Explanted hearts from seven patients (5 male, 46 ± 10 years) undergoing cardiac transplantation were Langendorff-perfused and mapped using an epicardial sock electrode array (112 electrodes) and 25 transmural plunge needles (four electrodes, 2 mm spacing), for a total of 100 unipolar transmural electrodes...
January 20, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28108547/characterising-the-difference-in-electrophysiological-substrate-and-outcomes-between-heart-failure-and-non-heart-failure-patients-with-persistent-atrial-fibrillation
#4
Shouvik K Haldar, David G Jones, Habib Khan, Sandeep Panikker, Julian W E Jarman, Charlie Butcher, Eric Lim, Gareth Wynn, Dhiraj Gupta, Wajid Hussain, Vias Markides, Tom Wong
AIMS: Characterizing the differences in substrate and clinical outcome between heart failure (HF) and non-heart failure (non-HF) patients undergoing persistent atrial fibrillation (AF) ablation. METHODS AND RESULTS: Using complex fractionated electrograms (CFE) as a surrogate marker of substrate complexity, we compared the bi-atrial substrate in patients with persistent AF with and without HF, at baseline and after ablation, to determine its impact on clinical outcome...
January 20, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28096289/left-juxtaposed-right-atrial-appendage-suspected-on-a-plain-chest-radiograph
#5
Naomi Gunadeva, Ruchit Shah, Gyanendra K Sharma, Jayanth H Keshavamurthy, Arie Franco
No abstract text is available yet for this article.
January 16, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28096288/mid-regional-pro-atrial-natriuretic-peptide-to-predict-clinical-course-in-heart-failure-patients-undergoing-cardiac-resynchronization-therapy
#6
Mattia Arrigo, Quynh A Truong, Jackie Szymonifka, Mercedes Rivas-Lasarte, Heli Tolppanen, Malha Sadoune, Etienne Gayat, Alain Cohen-Solal, Frank Ruschitzka, James L Januzzi, Jagmeet P Singh, Alexandre Mebazaa
AIMS: Cardiac resynchronization therapy (CRT) induces reverse cardiac remodelling in heart failure (HF), but many patients receiving CRT remain non-responders. This study assessed the role of amino-terminal-pro-B-type natriuretic peptide (NT-proBNP), mid-regional-pro-atrial natriuretic peptide (MR-proANP), and mid-regional-pro-adrenomedullin (MR-proADM) at the time of device implantation to predict favourable clinical course (CRT response and/or risk of MACE) in HF patients receiving CRT...
January 16, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28088764/prevalence-and-long-term-prognosis-of-patients-with-narrower-than-normal-qrs-complexes
#7
Philippe Maury, Elodie Lematte, Nicolas Derval, Anne Rollin, Vanina Bongard, Alexandre Duparc, Pierre Mondoly, Christelle Cardin, Marie Sadron, Michel Galinier, Didier Carrié, Meleze Hocini, Arnaud Denis, Pierre Jaïs, Frederic Sacher, Michel Haïssaguerre, Jean Ferrieres, Jean Bernard Ruidavets
AIMS: Very narrow QRS have been reported in sudden death survivors but prevalence and prognosis role of narrow QRS is unknown. METHODS AND RESULTS: 546 healthy men between 50 and 60 years (group 1) and 373 similar patients with coronary artery disease (368 men, group 2) underwent signal averaged ECG (SA-ECG) allowing precise measurement of QRS duration. All cause-mortality was determined after 18 ± 3 years follow-up. Mean QRS duration was 97 ± 13 ms in group 1 and 103 ± 16 ms in group 2...
January 14, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28087596/a-meta-analysis-on-the-prognostic-significance-of-inferolateral-early-repolarization-pattern-in-brugada-syndrome
#8
Stamatis Georgopoulos, Konstantinos P Letsas, Tong Liu, Maria Kalafateli, Panagiotis Korantzopoulos, Gerd Bürkle, Konstantinos Vlachos, Georgios Giannopoulos, Michael Efremidis, Spyridon Deftereos, Antonios Sideris, Masahiko Takagi, Gan-Xin Yan, Joachim R Ehrlich
AIMS: The early repolarization (ER) pattern has been linked to an increased risk for arrhythmic death in various clinical settings. There are limited and conflicting data regarding the prognostic significance of ER pattern in Brugada syndrome (BS). The aim of this meta-analysis was to provide a detailed analysis of the currently available studies regarding the arrhythmic risk in patients with BS and ER pattern. METHODS AND RESULTS: Current databases were searched until May 2015...
January 13, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28087595/is-epicardial-fat-depot-associated-with-atrial-fibrillation-a-systematic-review-and-meta-analysis
#9
Maddalena Gaeta, Francesco Bandera, Federico Tassinari, Capasso Lorenzo, Miriam Cargnelutti, Gabriele Pelissero, Alexis Elias Malavazos, Cristian Ricci
AIMS: Atrial fibrillation (AF) is the leading rhythm disorder in western countries. A direct relationship between left atrium (LA) enlargement and electromechanical remodelling has been established. A causative link between epicardial fat (EF), visceral adipose tissue deposited around the heart, and AF has been hypothesized. Several reports suggested the association between EF and the presence of AF. The aim of this study was to verify the relationship between AF and EF depot, performing a meta-analysis of observational case series studies...
January 13, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28082419/implantable-cardioverter-defibrillator-therapy-among-patients-with-non-ischaemic-vs-ischaemic-cardiomyopathy-for-primary-prevention-of-sudden-cardiac-death
#10
Nelly Amara, Serge Boveda, Pascal Defaye, Didier Klug, Fréderic Treguer, Denis Amet, Marie-Cécile Perier, Daniel Gras, Vincent Algalarrondo, Abdeslam Bouzeman, Olivier Piot, Jean-Claude Deharo, Laurent Fauchier, Dominique Babuty, Pierre Bordachar, Nicolas Sadoul, Eloi Marijon, Christophe Leclercq
AIM: The magnitude of benefit related to implantable cardioverter defibrillator (ICD) therapy for primary prevention of sudden cardiac death (SCD) in non-ischaemic cardiomyopathy (NICM) and ischaemic cardiomyopathy (ICM) has not been evaluated extensively in clinical practice. METHODS AND RESULTS: Of the 5539 consecutive patients enrolled in the multicentre Défibrillateur Automatique Implantable-Prévention Primaire (DAI-PP) study (2002-12), 5485 patients (with information on underlying heart disease) were included in the present analysis: 2181 (39...
January 12, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28082418/heterogeneous-distribution-of-substrates-between-the-endocardium-and-epicardium-promotes-ventricular-fibrillation-in-arrhythmogenic-right-ventricular-dysplasia-cardiomyopathy
#11
Chin-Yu Lin, Yenn-Jiang Lin, Cheng-Hung Li, Fa-Po Chung, Men-Tzung Lo, Chen Lin, Hsiang-Chih Chang, Shih-Lin Chang, Li-Wei Lo, Yu-Feng Hu, Yao-Ting Chang, Chung-Hsing Lin, Yun-Yu Chen, Rohit Walia, Abigail Louise D Te, Shinya Yamada, Tsu-Juey Wu, Shih-Ann Chen
AIMS: Whether the distribution of scar in arrhythmogenic right ventricular cardiomyopathy (ARVC) plays a role in predicting different types of ventricular arrhythmias is unknown. This study aimed to investigate the prognostic value of scar distribution in patients with ARVC. METHODS AND RESULTS: We studied 80 consecutive ARVC patients (46 men, mean age 47 ± 15 years) who underwent an electrophysiological study with ablation. Thirty-four patients receive both endocardial and epicardial mapping...
January 12, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28073887/perioperative-predictors-of-permanent-pacing-and-long-term-dependence-following-tricuspid-valve-surgery-a-multicentre-analysis
#12
Philip L Mar, Christopher R Angus, Rajesh Kabra, Christopher K Migliore, Rohan Goswami, Leah A John, Yixi Tu, Rakesh Gopinathannair
AIMS: Permanent pacemaker placement (PPM) is often required after valvular surgery and is especially common following tricuspid valve surgery [tricuspid valve repair or replacement (TVR)]. Literature suggests that surgical intervention for isolated tricuspid valve disease is becoming more prevalent. Predictors of PPM dependency following TVR are currently unknown and would be clinically useful from a prognostication standpoint. METHODS AND RESULTS: We conducted a multicentre, retrospective study to assess perioperative factors of TVR that predispose to PPM placement and long-term PPM dependency from 2008 to 2014...
January 10, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28073886/endocardial-left-ventricular-pacing-for-cardiac-resynchronization-systematic-review-and-meta-analysis
#13
James Hugo Phillimore Gamble, Neil Herring, Matthew Ginks, Kim Rajappan, Yaver Bashir, Timothy Rider Betts
AIMS: Endocardial left ventricular (LV) pacing for Cardiac Resynchronization Therapy has been proposed as an alternative to conventional LV lead placement via the coronary sinus. In order to assess the relative benefits and risks of this technique, we have performed a meta-analysis of published reports. METHODS AND RESULTS: A systemic search was performed using online databases to identify studies of lead-based endocardial pacing. A random-effects meta-analysis was performed, to assess the rate of complications and clinical response (defined as ≥1 decrease in NYHA class)...
January 10, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28073885/reduction-of-atrial-fibrillation-burden-by-pulmonary-vein-isolation-leads-to-a-decrease-of-cd11b-expression-on-inflammatory-cells
#14
Daniel Tarnowski, Lina Plichta, Mathias Forkmann, Silvio Quick, Stefan Ulbrich, Felix Matthias Heidrich, Stephan Wiedemann, Marian Christoph, David Maximilian Poitz, Carsten Wunderlich, Karim Ibrahim, Ruth H Strasser, Christian Pfluecke
AIMS: It is hypothesized that inflammation could promote structural and electrical remodelling processes in atrial fibrillation (AF). Atrial infiltration of monocytes and granulocytes has been shown to be dependent on CD11b expression. The aim of this study was to investigate whether treatment of AF by pulmonary vein isolation (PVI) may lead to reduced inflammation, as indicated by a decrease of CD11b expression on monocytes and granulocytes. METHODS AND RESULTS: Flow-cytometric quantification analysis and determination of systemic inflammatory markers of peripheral blood were performed in 75 patients undergoing PVI 1 day before and 6 months after PVI...
January 10, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28073884/pacemaker-detected-severe-sleep-apnea-predicts-new-onset-atrial-fibrillation
#15
Andrea Mazza, Maria Grazia Bendini, Raffaele De Cristofaro, Mariolina Lovecchio, Sergio Valsecchi, Giuseppe Boriani
AIMS: Sleep apnea (SA) diagnosed on overnight polysomnography is a risk factor for atrial fibrillation (AF). Advanced pacemakers are now able to monitor intrathoracic impedance for automatic detection of SA events. METHODS AND RESULTS: We enrolled 160 consecutive recipients of a dual-chamber pacemaker endowed with the ApneaScan algorithm (Boston Scientific). If the pacemaker-measured Respiratory Disturbance Index was ≥30 episodes per hour for at least one night during the first week after implantation, SA was defined as severe...
January 10, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28073883/infective-endocarditis-and-risk-of-death-after-cardiac-implantable-electronic-device-implantation-a-nationwide-cohort-study
#16
Cengiz Özcan, Jakob Raunsø, Morten Lamberts, Lars Køber, Tommi Bo Lindhardt, Niels Eske Bruun, Marie Louise Laursen, Christian Torp-Pedersen, Gunnar Hilmar Gislason, Morten Lock Hansen
AIMS: To determine the incidence, risk factors, and mortality of infective endocarditis (IE) following implantation of a first-time, permanent, cardiac implantable electronic device (CIED). METHODS AND RESULTS: From Danish nationwide administrative registers (beginning in 1996), we identified all de-novo permanent pacemakers (PMs) and implantable cardioverter defibrillators (ICDs) together with the occurrence of post-implantation IE-events in the period from 2000-2012...
January 10, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28073882/the-role-of-superior-vena-cava-in-catheter-ablation-of-long-standing-persistent-atrial-fibrillation
#17
Kai Xu, Yuanlong Wang, Shaohui Wu, Li Zhou, Liang Zhao, Weifeng Jiang, Xiaodong Zhang, Xu Liu
AIMS: The superior vena cava (SVC) has been established as an important source of atrial fibrillation (AF). The role of SVC in long-standing persistent AF and the efficacy of empiric electrical isolation of the SVC are still unclear. The purpose of this study was to judge the role of SVC in catheter ablation of long-standing persistent AF. METHODS AND RESULTS: A total of 102 consecutive patients with long-standing persistent AF were enrolled. All patients underwent circumferential pulmonary vein isolation, complex fractionated atrial electrograms ablation, and linear ablation during the index procedure...
January 9, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28069839/incidence-of-new-onset-atrial-fibrillation-after-cavotricuspid-isthmus-ablation-for-atrial-flutter
#18
Umut Celikyurt, Sven Knecht, Michael Kuehne, Tobias Reichlin, Aline Muehl, Florian Spies, Stefan Osswald, Christian Sticherling
AIMS: In patients with cavotricuspid isthmus (CTI) ablation for atrial flutter (AFL), the decision to hold oral anticoagulation (OAC) often becomes an issue. The purpose of this study was to describe the incidence of the development of atrial fibrillation (AF) after CTI ablation in patients with documented AFL with and without a previous history of AF and to identify risk predictors for the occurrence of AF after CTI. METHODS AND RESULTS: We included 364 consecutive patients undergoing successful CTI ablation...
January 8, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28069838/incidence-of-atrial-fibrillation-detected-by-continuous-rhythm-monitoring-after-acute-myocardial-infarction-in-patients-with-preserved-left-ventricular-ejection-fraction-results-of-the-arrest-study
#19
Alexander Romanov, Martin Martinek, Helmut Pürerfellner, Shaojie Chen, Mirko De Melis, Igor Grazhdankin, Dmitry Ponomarev, Denis Losik, Artem Strelnikov, Vitaliy Shabanov, Alexander Karaskov, Evgeny Pokushalov
AIMS: Cardiac arrhythmias following acute myocardial infarction (AMI) can be associated with major adverse cardiovascular events. Data on the "real incidence" of post-MI arrhythmias are limited. We aimed to determine the rate and burden of cardiac arrhythmias by the use of insertable cardiac monitors (ICM) in patients with preserved left ventricular ejection fraction (LVEF) after AMI. METHODS AND RESULTS: In this prospective observational study, patients with LVEF ≥40% who underwent PCI within 7 days following AMI were enrolled to receive an ICM...
January 8, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28069837/high-sensitive-cardiac-troponin-t-as-a-novel-predictor-for-recurrence-of-atrial-fibrillation-after-radiofrequency-catheter-ablation
#20
Koki Nakanishi, Shota Fukuda, Hajime Yamashita, Toshifumi Hasegawa, Michihiko Kosaka, Naoya Shirai, Kenei Shimada, Junichi Yoshikawa, Atsushi Tanaka
AIMS: We aimed to determine whether elevated serum high-sensitive cardiac troponin T (hs-TnT) levels predict atrial fibrillation (AF) recurrence after pulmonary vein isolation (PVI). METHODS AND RESULTS: We included 125 consecutive patients with AF (paroxysmal, n = 79; persistent, n = 46) who underwent first-time PVI. Serum hs-TnT, high-sensitive C-reactive protein (hs-CRP), atrial natriuretic peptide, and plasma B-type natriuretic peptide levels were measured in venous samples collected before PVI...
January 8, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
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