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Bipolar Disorders

journal
https://www.readbyqxmd.com/read/29227034/the-clinical-course-of-late-life-bipolar-disorder-looking-back-and-forward
#1
Annemiek Dols, Nicole Korten, Hannie Comijs, Sigfried Schouws, Moniek van Dijk, Ursula Klumpers, Aartjan Beekman, Ralph Kupka, Max Stek
OBJECTIVES: Little is known about the course of late-life bipolar disorder (LLBD). First, we studied patients with LLBD retrospectively with regard to age at first mood episode, onset polarity, predominant polarity and episode density and its associations with other clinical variables. Next, we examined prospectively the clinical course and its associated factors. METHODS: Data were used from a dynamic cohort (Dutch Older Bipolars [DOBi]) including 101 patients with LLBD (mean age of 68...
December 11, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/29227016/patients-with-chronic-bipolar-disorder-exhibit-widespread-increases-in-extracellular-free-water
#2
Carissa Tuozzo, Amanda E Lyall, Ofer Pasternak, Anthony C D James, Timothy J Crow, Marek Kubicki
OBJECTIVES: Bipolar disorder (BP) is a debilitating psychiatric disease that is not well understood. Previous diffusion magnetic resonance imaging (dMRI) studies of BP patients found prominent microstructural white matter (WM) abnormalities of reduced fractional anisotropy (FA). Because FA is a nonspecific measure, relating these abnormalities to a specific pathology is difficult. Here, dMRI specificity was increased by free water (FW) imaging, which allows identification of changes in extracellular space (FW) from neuronal tissue (fractional anisotropy of tissue [FA-t])...
December 11, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/29227012/superior-anti-suicidal-effects-of-electroconvulsive-therapy-in-unipolar-disorder-and-bipolar-depression
#3
Chih-Sung Liang, Chi-Hsiang Chung, Pei-Shen Ho, Chia-Kuang Tsai, Wu-Chien Chien
OBJECTIVES: Electroconvulsive therapy (ECT) has long been believed to reduce suicidal tendencies in patients with affective disorders; however, ECT recipients, who constitute the most severely ill and suicidal patients, are not eligible to participate in head-to-head randomized controlled trials. Large-scale studies are required to investigate the anti-suicidal effects of ECT vs psychopharmacotherapy. METHODS: A nationwide retrospective cohort study design was used...
December 11, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/29214732/commentary-on-methodological-recommendations-for-cognition-trials-in-bipolar-disorder-by-the-international-society-for-bipolar-disorders-targeting-cognition-task-force
#4
https://www.readbyqxmd.com/read/29214704/definition-of-the-term-mood-stabilizer
#5
Terence A Ketter
No abstract text is available yet for this article.
December 7, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/29214699/lithium-the-silver-lining-to-clouded-thinking
#6
Gin S Malhi, Tim Outhred
No abstract text is available yet for this article.
December 7, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/29168603/eye-gaze-perception-in-bipolar-disorder-self-referential-bias-but-intact-perceptual-sensitivity
#7
Beier Yao, Savanna A Mueller, Tyler B Grove, Merranda McLaughlin, Katharine Thakkar, Vicki Ellingrod, Melvin G McInnis, Stephan F Taylor, Patricia J Deldin, Ivy F Tso
OBJECTIVES: Deficits in social cognition predict poor functional outcome in severe mental illnesses such as schizophrenia and autism. However, research findings on social cognition in bipolar disorder (BD) are sparse and inconsistent. This study aimed to characterize a critical social cognitive process-eye gaze perception-and examine its functional correlates in BD to inform psychopathological mechanisms. METHODS: Thirty participants with BD, 37 healthy controls (HC), and 46 psychiatric controls with schizophrenia (SZ) completed an eye-contact perception task...
November 23, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/29148149/tinkering-at-the-margins
#8
Andrew M Chanen
No abstract text is available yet for this article.
November 17, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/29148147/altered-n170-and-mood-symptoms-in-bipolar-disorder-an-electrophysiological-study-of-configural-face-processing
#9
Ivy F Tso, Tyler B Grove, Savanna A Mueller, Lisa O'Donnell, Jinsoo Chun, Melvin G McInnis, Patricia J Deldin
OBJECTIVES: Altered social behavior during mood episodes in bipolar disorder often has detrimental and long-lasting interpersonal consequences. Abnormal face processing may play a role in linking brain functions to clinical symptoms and behavior. This study aimed to understand configural face processing in bipolar disorder as a function of basic communicative attributes of the face and mood symptoms using event-related brain potentials (ERPs). METHODS: Forty-two participants with bipolar I disorder (BP) and 43 healthy controls (HC) viewed face stimuli varying in emotion (neutral or fearful), head orientation (forward or deviated), and gaze direction (direct or averted) while ERPs were recorded...
November 17, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/29131495/old-treatment-and-new-curiosity-lithium-in-drinking-water
#10
Paul Grof
No abstract text is available yet for this article.
November 13, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/29131492/hastening-treatment-development-in-bipolar-disorder-evaluation-of-consensus-based-recommendations-for-cognition-trials
#11
Kathryn E Lewandowski
No abstract text is available yet for this article.
November 13, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/29121444/neurocognitive-functioning-clinical-course-and-functional-outcome-in-first-treatment-bipolar-i-disorder-patients-with-and-without-clinical-relapse-a-1-year-follow-up-study
#12
Christine Demmo, Trine V Lagerberg, Levi R Kvitland, Sofie R Aminoff, Tone Hellvin, Carmen Simonsen, Beathe Haatveit, Ole A Andreassen, Ingrid Melle, Torill Ueland
OBJECTIVES: Due to limited research on the association between recurrence of mood episodes and the longitudinal course of neurocognitive functioning in early phase bipolar I disorder (BD I), the impact of recurrence on neurocognition remains unclear. Further, a strong correlation between neurocognitive impairment and functional impairment has been demonstrated. The longitudinal relationship between neurocognitive impairment and functional outcome in relation to recurrence is, however, not established...
November 9, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/29120507/long-acting-risperidone-injections-in-a-pregnant-patient-with-bipolar-disorder
#13
(no author information available yet)
No abstract text is available yet for this article.
November 9, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/29116664/unraveling-the-biology-of-bipolar-disorder-using-induced-pluripotent-stem-derived-neurons
#14
REVIEW
Nathaniel D Miller, John R Kelsoe
OBJECTIVES: Bipolar disorder has been studied from numerous angles, from pathological studies to large-scale genomic studies, overall making moderate gains toward an understanding of the disorder. With the advancement of induced pluripotent stem (iPS) cell technology, in vitro models based on patient samples are now available that inherently incorporate the complex genetic variants that largely are the basis for this disorder. A number of groups are starting to apply iPS technology to the study of bipolar disorder...
November 8, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/29108106/measurement-tools-for-assessment-of-older-age-bipolar-disorder-a-systematic-review-of-the-recent-global-literature
#15
Soham Rej, William Quayle, Brent P Forester, Annemiek Dols, Jennifer Gatchel, Peijun Chen, Sarah Gough, Rebecca Fox, Martha Sajatovic, Sergio A Strejilevich, Lisa T Eyler
OBJECTIVES: More than 50% of people with bipolar disorder will be age 60 years or older by 2030. There is a need for more data to guide assessment and treatment in older age bipolar disorder (OABD); however, interpretation of findings from small, single-site studies may not be generalizable and there are few large trials. As a step in the direction of coordinated large-scale OABD data collection, it is critical to identify which measurements are currently used and identify potential gaps in domains typically assessed...
November 6, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/29024302/reduced-electroencephalogram-responses-to-standard-and-target-auditory-stimuli-in-bipolar-disorder-and-the-impact-of-psychotic-features-analysis-of-event-related-potentials-spectral-power-and-inter-trial-coherence
#16
Nancy B Lundin, Lisa A Bartolomeo, Brian F O'Donnell, William P Hetrick
BACKGROUND: Bipolar disorder (BD) is associated with reductions in the P3b event-related potential (ERP) response to target auditory stimuli, which suggests deficits in context updating. Previous studies have typically examined these responses in the temporal domain, which may not capture alterations in specific frequencies of phase-locked or induced electrophysiological activity. Therefore, the present study examined early and late ERPs in temporal and frequency domains in a bipolar sample with and without current psychotic features...
October 11, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/29024194/disrupted-cortico-limbic-connectivity-during-reward-processing-in-remitted-bipolar-i-disorder
#17
Sunny J Dutra, Vincent Man, Hedy Kober, William A Cunningham, June Gruber
OBJECTIVES: Bipolar disorder (BD) is associated with elevated reward sensitivity and persistent positive affect, yet the neural mechanisms underlying these patterns are not well understood. In the present study, we examined putative disruptions in communication within a well-known cortico-limbic reward circuit during reward processing as a potential contributing mechanism to these symptoms. METHODS: The present investigation employed a within- and between-subjects design utilizing a monetary and social incentive delay task among adults with bipolar disorder type I (BD; N = 24) and a healthy non-psychiatric control group (HC; N = 25) during functional magnetic resonance imaging (fMRI)...
October 11, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/28992395/changes-in-white-matter-microstructure-predict-lithium-response-in-adolescents-with-bipolar-disorder
#18
Vivian Kafantaris, Linda Spritzer, Vishal Doshi, Ema Saito, Philip R Szeszko
OBJECTIVES: To investigate whether response to lithium treatment in pediatric bipolar disorder can be predicted by changes in white matter microstructure in key cortico-limbic tracts involved in emotion regulation. METHODS: Eighteen clinically referred lithium-naive patients (mean age 15.5 years) were administered clinical rating scales and diffusion tensor imaging (DTI) examinations at baseline and following 4 weeks of lithium treatment. Clinical ratings were repeated following 8 weeks of treatment...
October 9, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/28987022/debate-on-defining-melancholia-a-core-mood-disorder
#19
Lucas Primo de Carvalho Alves, Neusa Sica da Rocha
OBJECTIVES: Recently, a debate article by Parker et al. was published regarding the biological type of depression, melancholia, in which they discussed its clinical presentation, particularly that involving psychomotor disturbances. However, there is one feature of melancholia that is frequently forgotten, to which this article aims to devote special attention: ruminative thoughts of guilt. METHODS: A critical review of the literature. RESULTS: The symptom of ruminative thoughts of guilt has been described historically in melancholia, and some recent data, such as neurobiological abnormalities and poor prognosis, support it as an important feature of depression...
October 7, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/28944987/the-international-society-for-bipolar-disorders-task-force-report-on-pediatric-bipolar-disorder-knowledge-to-date-and-directions-for-future-research
#20
Benjamin I Goldstein, Boris Birmaher, Gabrielle A Carlson, Melissa P DelBello, Robert L Findling, Mary Fristad, Robert A Kowatch, David J Miklowitz, Fabiano G Nery, Guillermo Perez-Algorta, Anna Van Meter, Cristian P Zeni, Christoph U Correll, Hyo-Won Kim, Janet Wozniak, Kiki D Chang, Manon Hillegers, Eric A Youngstrom
OBJECTIVES: Over the past two decades, there has been tremendous growth in research regarding bipolar disorder (BD) among children and adolescents (ie, pediatric BD [PBD]). The primary purpose of this article is to distill the extant literature, dispel myths or exaggerated assertions in the field, and disseminate clinically relevant findings. METHODS: An international group of experts completed a selective review of the literature, emphasizing areas of consensus, identifying limitations and gaps in the literature, and highlighting future directions to mitigate these gaps...
September 25, 2017: Bipolar Disorders
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