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Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology

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https://www.readbyqxmd.com/read/28952239/hallmarks-in-history-of-esophageal-carcinoma
#1
Marianna Karamanou, Kostas Markatos, Theodoros G Papaioannou, George Zografos, George Androutsos
Esophageal cancer is one of the deadliest cancers due to its aggressive behavior and poor survival. It was mentioned in the works of ancient Chinese and Arabo-islamic physicians, centuries before the recognition of high incidence in the Asian esophageal cancer belt. Till the 19th century the disease was considered incurable and the main goal of the proposed treatments was to alleviate dysphagia and pain. The introduction of esophagoscope in 1868 by Adolf Kussmaul (1822-1902) contributed to the observation of the living esophagus and to the diagnosis of esophageal pathologies, paving the way for new therapeutic approaches...
July 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28952238/prognosis-of-women-with-invasive-pleomorphic-lobular-carcinoma-compared-with-classical-invasive-lobular-carcinoma-still-debatable-issue
#2
Kadri Altundag
No abstract text is available yet for this article.
July 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28952237/the-role-of-nutrition-in-the-prevention-of-prostatic-adenocarcinoma
#3
Charalampos Fragkoulis, Ioannis Glykas, Ioannis Gkialas, Konstantinos Ntoumas
No abstract text is available yet for this article.
July 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28952236/should-patients-with-her2-loss-after-neoadjuvant-treatment-still-be-treated-with-adjuvant-trastuzumab-treatment
#4
Kadri Altundag
No abstract text is available yet for this article.
July 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28952235/anatomical-variations-in-the-human-body
#5
Christos-David Papaloucas, Ioanna Kantzou, Georgios Sarris, Vassilis Kouloulias
No abstract text is available yet for this article.
July 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28952234/synchronous-double-primary-gastric-tumors-sarcoma-and-adenocarcinoma
#6
Tania Triantafyllou, Haridimos Markogiannakis, Georgios Zografos, Dimitrios Theodorou
No abstract text is available yet for this article.
July 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28952233/t1-invasive-breast-lobular-tumor-and-ductal-carcinoma-with-her-2-positive-characteristics-is-it-rationale-to-use-adjuvant-trastuzumab
#7
Kadri Altundag
No abstract text is available yet for this article.
July 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28952232/novel-techniques-for-morphometric-and-geometrical-analysis-in-squamous-intraepithelial-lesions-on-cervical-smears
#8
Evangelos Tsiambas, Christos Riziotis, Ismini Mavrikos, Elias Armatas, Efstratios Patsouris
No abstract text is available yet for this article.
July 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28952231/metastasis-acquired-changes-in-clinically-actionable-genes-in-triple-negative-breast-cancer-patients-with-central-nervous-system-metastases-focus-on-her2-targeted-therapies
#9
Kadri Altundag
No abstract text is available yet for this article.
July 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28952230/how-can-we-effectively-address-the-paraneoplastic-dermatomyositis-diagnosis-risk-factors-and-treatment-options
#10
Ioannis Zerdes, Maria Tolia, Michail Nikolaou, Nikolaos Tsoukalas, Louloudenia Velentza, Jiannis Hajiioannou, Michail Mitsis, George Kyrgias
PURPOSE: Dermatomyositis (DM) represents an auto-immune inflammatory myopathy. In this review, we analyzed the incidence of DM as a clinical manifestation highlighting the peculiar clinical and treatment characteristics of this disease when occurring in the context of different malignancies. METHODS: A systematic literature review was performed based on database search in PubMed/Medline and included English articles until December 2016. RESULTS: In up to 20% of cases DM appears as a paraneoplastic syndrome associated with multiple malignancies such as ovarian, breast, prostate, lung, nasopharyngeal and colorectal cancer, and non-Hodgkin lymphomas...
July 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28952229/the-function-of-dream-gene-mediated-by-nf-kb-signal-pathway-in-the-pathogenesis-of-osteosarcoma
#11
Jize Qian, Mignbo Lv, Wenbo Zhang
PURPOSE: To explore the function of DREAM gene mediated by NF-kB signal pathway in the pathogenesis of osteosarcoma. METHODS: This study included 13 Sprague Dawley (SD) rats with osteosarcoma (treatment group) and 13 healthy rats (control group). NF-kB, DREAM and P105 mRNAs expression levels were determined using quantitative PCR (qPCR). The expression levels of NF-kB, DREAM and P105 proteins were evaluated using ELISA and western blot. Also, DREAM protein expression in rats was determined by immunofluorescence...
July 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28952228/differentiation-between-progression-and-pseudoprogresion-by-arterial-spin-labeling-mri-in-patients-with-glioblastoma-multiforme
#12
Marija Jovanovic, Sandra Radenkovic, Tatjana Stosic-Opincal, Slobodan Lavrnic, Svetlana Gavrilovic, Biljana Lazovic-Popovic, Ivan Soldatovic, Ruzica Maksimovic
PURPOSE: To compare arterial spin labeling (ASL) perfusion technique with the clinically established dynamic susceptibility contrast-enhanced (DSC) perfusion weighted-imaging (PWI), and to determine its value in routine MRI evaluation of disease progression in patients with glioblastoma multiforme (GBM). METHODS: A prospective intraindividual study was performed in 31 patients with histologically proven GBM who had clinical and/or radiological deterioration after treatment, including surgery, radiotherapy and therapy with temozolomide...
July 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28952227/analysis-of-the-status-of-egfr-ros1-and-met-genes-in-non-small-cell-lung-adenocarcinoma
#13
Qiong Wang, Yali Lv, Mei Zhong, Fengwei Zhu, Lixin Wei, Huaiyin Shi
PURPOSE: To investigate the status and distribution of epidermal growth factor receptor (EGFR), hepatocyte growth factor receptor (MET), and receptor tyrosine kinase (ROS1) genes in patients with non-small cell lung (NSCL) adenocarcinoma. METHODS: The copy number of the MET gene was detected using fluorescence in situ hybridization (FISH). The splice mutation in exon 14 gene was detected by Sanger sequencing. The mutations in EGFR and the fusion of the ROS1 gene were detected using the fluorescence real-time quantitative PCR method (RT-qPCR)...
July 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28952226/chemoradiotherapy-after-gemcitabine-plus-erlotinib-in-patients-with-locally-advanced-pancreatic-cancer
#14
Eunji Kim, Kyubo Kim, Eui Kyu Chie, Do-Youn Oh, Yong Tae Kim
PURPOSE: To evaluate the outcomes of chemoradiotherapy (CRT) after neoadjuvant chemotherapy consisting of gemcitabine and erlotinib for unresectable locally advanced pancreatic cancer. METHODS: Between 2010 and 2014, 24 patients with unresectable pancreatic cancer received neoadjuvant gemcitabine/erlotinib followed by CRT. There were 9 men and 15 women, and median age was 61 years (range 48-77). Radiotherapy (RT) was delivered to the tumor and regional lymph nodes with a median dose of 50...
July 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28952225/vhl-tgfbi-signaling-is-involved-in-the-synergy-between-5-aza-2-deoxycytidine-and-paclitaxel-against-human-renal-cell-carcinoma
#15
Donghao Shang, Shaozhong Xian, Tiandong Han, Xuanhao Li, Yuting Liu
PURPOSE: To analyse the role of von Hippel-Lindau (VHL) and transforming growth factor β-induced (TGFBI) in synergistic mechanisms of 5-aza-2'-deoxycytidine (DAC) and paclitaxel (PTX) against renal cell carcinoma (RCC). METHODS: To elucidate the role in the synergy between DAC and PTX against RCC cells, TGFBI expression was regulated using siRNA technology and an expression vector containing the full-length cDNA for TGFBI was also transfected into RCC cells. The proliferation of RCC cells was evaluated using the WST-1 assay and TGFBI expression was detected by real-time PCR (RT-PCR), and Western blot...
July 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28952224/increased-expression-of-platelet-derived-growth-factor-receptor-%C3%AE-on-trephine-biopsies-correlates-with-advanced-myeloma
#16
Antonios Bilalis, Evi Pouliou, Maria Roussou, Asimina Papanikolaou, Anna Tassidou, Theophanis Economopoulos, Evangelos Terpos
PURPOSE: Multiple myeloma (MM), a major cause of cancer mortality, is considered the second most frequent haematological malignancy in Europe. Angiogenesis is a multifactorial process that drives the tumorigenesis in solid tumors and in MM. The platelet derived growth factor (PDGF) receptors are cell surface tyrosine kinase receptors and play an important role in angiogenesis, cancer cell proliferation and dissemination. Few studies have been conducted regarding the expression of PDGF receptors and the correlation with clinical-pathological parameters and prognosis in MM...
July 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28952223/protein-z-pz-and-plasminogen-activator-inhibitor-1-pai-1-plasma-levels-in-patients-with-previously-untreated-hodgkin-lymphoma-hl
#17
Georgios Boutsikas, Evangelos Terpos, Athanasios Markopoulos, Athanasios Papatheodorou, Angeliki Stefanou, George Georgiou, Zacharoula Galani, Veroniki Komninaka, Vasileios Telonis, Ioannis Anagnostopoulos, Lila Dimitrakopoulou, Konstantinos Anargyrou, Konstantinos Tsionos, Dimitrios Christoulas, Maria Gonianaki, Theophanis Giannikos, Styliani Kokoris, Kostas Konstantopoulos, John Meletis, Maria K Angelopoulou, Anthi Travlou, Theodoros P Vassilakopoulos
PURPOSE: The role of Protein Z (PZ) in conditions, such as thrombosis, inflammation or cancer, is under investigation. Plasminogen Activator Inhibitor-1 (PAI-1) is an acute phase reactant that promotes thrombosis and tumorigenesis. Subject of this work was to study PZ and PAI-1 in patients with Hodgkin Lymphoma (HL), a malignancy with inflammatory background and relatively low incidence of thrombosis. METHODS: Newly diagnosed patients were enrolled in the study...
July 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28952222/significance-of-the-detection-of-tim-3-and-foxj1-in-prostate-cancer
#18
Yong Lan, Xiaohui Hu, Kehua Jiang, Wei Yuan, Fu Zheng, Hongbo Chen
PURPOSE: This study sought to identify and evaluate the diagnostic value of T-cell immunoglobulin domain and mucin-3 (TIM-3) and forkhead box protein J1 (FOXJ1) expression in prostate cancer. METHODS: Thirty prostate cancer patients and 30 individuals with benign prostatic hyperplasia diagnosed and treated at the Central Hospital of Enshi Autonomous Prefecture between March 2016 and October 2016 were selected for this study. The expression of TIM-3 and FOXJ1 in patient prostate tissue was detected by immunohistochemistry and reverse transcription-polymerase chain reaction (RT-PCR)...
July 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28952221/research-of-the-effect-of-mir-663-on-the-proliferation-of-prostate-cancer-cells-and-the-correlations-of-mir-663-with-pathological-grade-and-clinical-stage
#19
Shifeng Wang, Jingsong Liu, Changming Li, Xue Yang
PURPOSE: To investigate the effect of miR-663 on the proliferation of prostate cancer (PCa) cells, and the correlations of miR-663 with pathological grade and clinical stage. METHODS: PC-3 and DU-145 PCa cell lines were transfected by artificially synthesized miR-663 and its antisense plasmid, and cell proliferation was assessed using 5-ethynyl-2'-deoxyuridine and methyl thiazolyl tetrazolium assays. Real-time polymerase chain reaction (RT-PCR) was applied to assess the expression of miR-663 in tissue samples collected from 46 patients who were diagnosed with PCa but did not receive any treatment...
July 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28952220/cetuximab-versus-nimotuzumab-for-the-treatment-of-advanced-nasopharyngeal-carcinoma-a-network-meta-analysis
#20
Cheng Yuan, Xin-Hua Xu, Lu Xu, Yang Liu, Min Sun, Li-Hua Ni, Xiao-Long Wang, Zhuo Chen, Kun Zhang, Hua-Li Wan, Guang Zeng
PURPOSE: We conducted a network meta-analysis to evaluate the efficacy and toxicity of cetuximab and nimotuzumab in the treatment of advanced nasopharyngeal carcinoma (NPC). METHODS: A systematic literature search was performed though Pubmed, Embase, Cochran Library, China National Knowledge Infrastructure (CNKI), Chinese Biomedical (CBM) and Wanfang databases. Totally, 19 randomized controlled trials (RCTs) (n=1201) met the study selection criteria and were incorporated in this network meta-analysis...
July 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
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