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Wiener Klinische Wochenschrift

Peter Valent, Emir Hadzijusufovic, Thomas Grunt, Heidrun Karlic, Barbara Peter, Harald Herrmann, Gregor Eisenwort, Gregor Hoermann, Axel Schulenburg, Michael Willmann, Rainer Hubmann, Medhat Shehata, Edgar Selzer, Karoline V Gleixner, Thomas Rülicke, Wolfgang R Sperr, Brigitte Marian, Michael Pfeilstöcker, Hubert Pehamberger, Felix Keil, Ulrich Jäger, Christoph Zielinski
In 2008 the Ludwig Boltzmann Cluster Oncology (LBC ONC) was established on the basis of two previous Ludwig Boltzmann Institutes working in the field of hematology and cancer research. The general aim of the LBC ONC is to improve treatment of hematopoietic neoplasms by eradicating cancer-initiating and disease-propagating cells, also known as leukemic stem cells (LSC) in the context of leukemia. In a first phase, the LBC ONC characterized the phenotype and molecular aberration profiles of LSC in various malignancies...
July 13, 2018: Wiener Klinische Wochenschrift
Olaf Kahl
There are various arthropods (e.g. insects, chiggers, mites, ticks) that take one or more blood meals on terrestrial vertebrates in the course of their lifetime. Among them are ixodid ticks (Acari, Ixodidae), all of which are obligately hematophagous. Their parasitic lifestyle predestines them to act as transmitters or vectors of microparasites, often pathogenic to humans and/or domestic animals. The list of ixodid tick-borne pathogens is long, encompassing viruses, bacteria, protozoans, and nematodes. The present mini-review gives a brief overview of the most relevant biological attributes that make ixodid ticks very efficient vectors compared with other hematophagous arthropod taxa...
July 13, 2018: Wiener Klinische Wochenschrift
Christian Smolle, Gerald Sendlhofer, Janos Cambiaso-Daniel, Michaela Sljivich, Herwig Friedl, Lars-Peter Kamolz, Gernot Brunner
BACKGROUND: In Austria, elaborate definitions exist for the undesirable medical events side effect, adverse event, complication and medical malpractice. We aimed at investigating whether the official definitions for the abovementioned terms can be understood by a sample population representing a cross-section of the Austrian population. METHODS: In this study 1021 Austrian citizens were interviewed. Demographic parameters (age, gender, occupation, level of education, monthly income, number of inhabitants at place of residence) were assessed...
July 12, 2018: Wiener Klinische Wochenschrift
Ante Tonkic, Jonatan Vukovic, Pavle Vrebalov Cindro, Valdi Pesutic Pisac, Marija Tonkic
Helicobacter pylori infections represent an important factor in the pathogenesis of chronic gastritis, peptic ulcer, MALT lymphoma and gastric adenocarcinoma. The recently published Maastricht V/Florence consensus report indicated that the urea breath test using 13 C urea still remains the best non-invasive test to diagnose H. pylori infections with high sensitivity and specificity. Among the stool antigen tests, the ELISA monoclonal antibody test is a rational option. Effective therapy should be based only on susceptibility testing in regions with documented high clarithromycin resistance (>15%)...
June 29, 2018: Wiener Klinische Wochenschrift
H Trimmel, R Helbok, T Staudinger, W Jaksch, B Messerer, H Schöchl, R Likar
Correction to: Wien Klin Wochenschr 2017 The article S(+)-ketamine Current trends in emergency and intensive caremedicine, written by Helmut Trimmel, Raimund Helbok, Thomas Staudinger, Wolfgang Jaksch, Brigitte Messerer, Herbert Schöchl and Rudolf Likar, was ….
June 29, 2018: Wiener Klinische Wochenschrift
Bernhard Scheiner, Paul René Stammet, Sebastian Pokorny, Theresa Bucsics, Philipp Schwabl, Andrea Brichta, Johannes Thaler, Katharina Lampichler, Ahmed Ba-Ssalamah, Cihan Ay, Arnulf Ferlitsch, Michael Trauner, Mattias Mandorfer, Thomas Reiberger
BACKGROUND: Non-malignant portal vein thrombosis (PVT) is common in patients with advanced liver disease. Anticoagulation (AC) increases the chances of recanalization and may improve liver function in patients with cirrhosis. AIM: We retrospectively assessed the course of non-malignant PVT in patients receiving AC. METHODS: Parameters related to hepatic injury (aspartate aminotransferase [AST]/alanine aminotransferase [ALT]), severity of disease (ascites) and synthesis function (albumin) as well as AC, rates of PVT regression/progression and AC-associated complications were documented...
June 18, 2018: Wiener Klinische Wochenschrift
Herwig Czech, Christiane Druml, Paul Weindling
No abstract text is available yet for this article.
June 8, 2018: Wiener Klinische Wochenschrift
Yiğit Çanga, Tolga Sinan Güvenç, Ali Nazmi Çalık, Mehmet Baran Karataş, Evliya Akdeniz, Gizem Yüksel, Ayşe Emre
BACKGROUND: Warfarin-related nephropathy (WRN) is a complication of warfarin over-anticoagulation that is associated with acute and/or chronic renal dysfunction and increased mortality. The long-term effects of warfarin on renal function has not been adequately studied in patients with a mechanical prosthetic valve (MPV). AIM: To study the time-dependent effects of over-anticoagulation on renal function in patients with a MPV. METHODS: A total of 193 patients who underwent MPV implantation and were followed up in this study were eligible for inclusion...
June 4, 2018: Wiener Klinische Wochenschrift
Christoph Edlinger, Marcel Granitz, Vera Paar, Christian Jung, Alexander Pfeil, Sarah Eder, Bernhard Wernly, Jürgen Kammler, Klaus Hergan, Uta C Hoppe, Clemens Steinwender, Michael Lichtenauer, Alexander Kypta
BACKGROUND: Leadless pacemaker systems are an important upcoming device in clinical rhythmology. Currently two different products are available with the Micra system (Medtronic) being the most used in the clinical setting to date. The possibility to perform magnetic resonance imaging (MRI) is an important feature of modern pacemaker devices. Even though the Micra system is suitable for MRI, little is yet known about its impact on artifacts within the images. OBJECTIVE: The aim of our ex vivo study was to perform cardiac MRI to quantify the artifacts and to evaluate if artifacts limit or inhibit the assessment of the surrounding myocardium...
May 23, 2018: Wiener Klinische Wochenschrift
Irene M Lang
Guidelines and recommendations are designed to guide physicians in making decisions in daily practice. Guidelines provide a condensed summary of all available evidence at the time of the writing process. Recommendations take into account the risk-benefit ratio of particular diagnostic or therapeutic means and the impact on outcome, but not monetary or political considerations. Guidelines are not substitutes but are complementary to textbooks and cover the European Society of Cardiology (ESC) core curriculum topics...
May 23, 2018: Wiener Klinische Wochenschrift
Yusuf I Alihanoglu, Bekir S Yildiz, Emin E Özcan, Ismail D Kilic, Deniz S Kuru, Ozgur Taskoylu, Halil Tanriverdi, Havane A Kaftan, Harun Evrengul
Correction to: Wien Klin Wochenschr 2015 The original version of this article unfortunately contained a mistake. The first names of Dr. Ismail Dogu Kilic were interchanged.
May 7, 2018: Wiener Klinische Wochenschrift
Konstantin D Bergmeister, Martin Aman, Bruno K Podesser
BACKGROUND: New regulations for working hours of medical doctors have been implemented in Austria based on the European directive 2003/88/EG, limiting on-duty working hours to 48 h per week. Clinical work is, therefore, substantially reduced compared to previous decades, and little is known on physician and students' opinions on this matter. We illustrate survey results concerning on-job training, its difficulties, and implications for restricted working hours. METHODS: We conducted an internal survey among M...
April 27, 2018: Wiener Klinische Wochenschrift
(no author information available yet)
No abstract text is available yet for this article.
July 2018: Wiener Klinische Wochenschrift
Philipp Wohlfarth
No abstract text is available yet for this article.
July 2018: Wiener Klinische Wochenschrift
(no author information available yet)
No abstract text is available yet for this article.
June 2018: Wiener Klinische Wochenschrift
(no author information available yet)
No abstract text is available yet for this article.
June 2018: Wiener Klinische Wochenschrift
Jianmei Zhang, Wenbin Chen, Li Fang, Qiu Li, Xu Zhang, Haiqing Zhang, Qingbo Guan, Rang Zhao, Chongbo Yang, Fei Jing
Nonalcoholic fatty liver disease (NAFLD) currently represents the most common hepatic disease worldwide and is closely linked to cardiovascular disease, obesity and diabetes mellitus. This study aimed to investigate NAFLD and its influence on different monocyte subpopulations to determine the presence of significant associations. A total of 3 monocyte subpopulations were investigated, i.e. classical (CD14++CD16-), intermediate (CD14++CD16+) and non-classical (CD14+CD16++). Of the participants 261 were included in this study (n = 53 with NAFLD, n = 208 controls)...
June 2018: Wiener Klinische Wochenschrift
Firuzan Sari Kundt, Nina Enthaler, Anna Maria Dieplinger, Michael Studnicka, Anna Knoll, Jürgen Osterbrink, Tim Johansson, Maria Flamm
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a frequent disease of the lungs. Its prevalence was estimated to be 26% in the Global Initiative for Chronic Obstructive Lung Disease (GOLD) I and 11% for GOLD II-IV in Austria. Globally, it ranks third in mortality rate. The particular challenge is that care for these patients falls short due to the lack of structured integrated care. The aim was to assess the current status of multiprofessional COPD care in Austria and identify gaps and potentials...
June 2018: Wiener Klinische Wochenschrift
Gabriele Reiger, Ralf Zwick, Bernd Lamprecht, Christian Kähler, Otto Chris Burghuber, Arschang Valipour
BACKGROUND: Chronic obstructive pulmonary disease (COPD) represents a major global health problem; however, there are no data regarding clinical phenotypes of these patients in Austria. METHODS: This was an analysis from the Austrian cohort of the cross-sectional Phenotypes of COPD in Central and Eastern Europe (POPE) study, which was offered to patients with stable COPD in a real-life setting. Patients were recruited at 5 different outpatient facilities in 3 different provinces in Austria...
June 2018: Wiener Klinische Wochenschrift
Konstantin D Bergmeister, Martin Aman, Bruno K Podesser
Correction to: Wien Klin Wochenschr 2018 The original version of this article unfortunately contained a mistake. The presentation of the sentence "limiting on-duty working hours to 58h per week." was incorrect. The correct limitation of the on-duty working ….
June 2018: Wiener Klinische Wochenschrift
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