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Wiener Klinische Wochenschrift

Anselm K Gitt, Johannes Rieber, Rainer Hambrecht, Johannes Brachmann, Kristof Graf, Martin Horack, Barbara Karmann, Ami Vyas, Dominik Lautsch, Baishali Ambegaonkar, Philippe Brudi
OBJECTIVE: To document utilization of lipid-lowering therapy, attainment of low-density lipoprotein cholesterol target values, and cardiovascular outcomes in patients hospitalized for acute coronary syndrome in Germany. METHODS: The Dyslipidemia International Study II was a multicenter, observational study of the prevalence of dyslipidemia and lipid target value attainment in patients surviving any acute coronary syndrome event. Among patients on lipid-lowering therapy for ≥3 months, use of lipid-lowering therapy and lipid profiles were assessed at admission and again at 120 ± 15 days after admission (the follow-up time point)...
September 3, 2018: Wiener Klinische Wochenschrift
Katrin Hefler-Frischmuth, Christoph Grimm, Lisa Gensthaler, Elisabeth Reiser, Richard Schwameis, Lukas A Hefler
BACKGROUND: Preoperative hyponatremia and thrombocytosis are associated with perioperative morbidity in patients with epithelial ovarian cancer (EOC). The aim of the present study was to evaluate preoperative hyponatremia and thrombocytosis as prognostic parameters in patients with EOC. METHODS: In a retrospective cohort study, serum levels of sodium and thrombocyte counts were evaluated in 498 patients with EOC. Data were extracted from the prospectively maintained database...
September 3, 2018: Wiener Klinische Wochenschrift
Maja Prutki, Ana Marija Alduk, Ranko Smiljanic
No abstract text is available yet for this article.
August 31, 2018: Wiener Klinische Wochenschrift
Katharina Kerschan-Schindl, Gerold Ebenbichler, Ursula Föeger-Samwald, Harald Leiss, Christina Gesslbauer, Malvina Herceg, Georg Stummvoll, Rodrig Marculescu, Richard Crevenna, Peter Pietschmann
BACKGROUND: Chronic inflammation of rheumatoid arthritis (RA) is associated with disturbances in muscle and bone metabolism. AIM: The purpose of this study was to investigate whether endocrine regulators of myogenesis and bone metabolism in patients with rheumatoid arthritis (RA) in remission differed from unaffected healthy controls. An additional point was whether these were associated with patients' health-related functioning or particular bodily functions of the International Classification of Functioning, Disability and Health (ICF)...
August 31, 2018: Wiener Klinische Wochenschrift
Dietmar Tamandl, Ahmed Ba-Ssalamah, Gernot Böhm, Klaus Emmanuel, Rosemarie Forstner, Reinhold Függer, Benjamin Henninger, Oliver Koch, Claus Kölblinger, Hans-Jörg Mischinger, Wolfgang Schima, Helmut Schöllnast, Stefan Stättner, Klaus Kaczirek
Rapid advances in imaging technology have improved the detection, characterization and staging of colorectal liver metastases, hepatocellular carcinoma and cholangiocarcinoma. A variety of imaging modalities are available and play a pivotal role in the work-up of patients, particularly as imaging findings determine resectability. Surgery often represents the only measure that can render long-term survival possible. Imaging is also indispensable for the assessment of responses to neoadjuvant treatment and for the detection of recurrence...
August 30, 2018: Wiener Klinische Wochenschrift
Eva Asamer, Joanna Szkandera, Paul Gibiser, Anna Lena Lembeck, Tatjana Stojakovic, Peter Kornprat, Caroline Lackner, Thomas Winder, Konstantin Schlick, Herbert Stöger, Armin Gerger, Martin Pichler, Michael Stotz
BACKGROUND AND AIM: The aim of this study was to investigate the prognostic relevance of plasma amylase and lipase concerning survival of patients suffering from metastatic pancreatic cancer (PC). METHOD: This retrospective study included 351 patients with metastatic PC, who were treated in a single academic institution. Cancer-specific survival (CSS) was analyzed using the Kaplan-Meier method. To further evaluate the prognostic significance of lipase and amylase, univariate and multivariate values were calculated using Cox proportional models...
August 21, 2018: Wiener Klinische Wochenschrift
Thomas Gremmel, Alexander Niessner, Hans Domanovits, Martin Frossard, Gürkan Sengölge, Barbara Steinlechner, Thomas Sycha, Michael Wolzt, Ingrid Pabinger
The non-vitamin K antagonist oral anticoagulants (NOACs) have considerably changed clinical practice and are increasingly being used as an alternative to vitamin K antagonists (VKAs) for 3 main reasons: 1) an improved benefit-risk ratio (in particular lower rates of intracranial bleeding), 2) a more predictable effect without the need for routine monitoring, and 3) fewer food and drug interactions compared with VKAs. Currently, there are four NOACs available: the factor Xa inhibitors apixaban, edoxaban, and rivaroxaban, and the thrombin inhibitor dabigatran...
August 20, 2018: Wiener Klinische Wochenschrift
Martina Krajnc, Matevz Jan, Katja Azman Juvan, Tomislav Klokocovnik
No abstract text is available yet for this article.
August 15, 2018: Wiener Klinische Wochenschrift
Miklos Rohla, Maximilian Tscharre, Kurt Huber, Thomas W Weiss
BACKGROUND: In Austria only 41% of patients with treated hypertension (HTN) have their blood pressure (BP) controlled. This study investigated a strategy to improve BP control in primary care. METHODS: General practitioners (GPs) were randomized to interventional care vs. standard care and included patients with uncontrolled office BP > 140/90 mm Hg. In interventional care, antihypertensive therapy was up-titrated using a single pill combination (olmesartan, amlodipine and/or hydrochlorothiazde) in 4‑week intervals...
August 15, 2018: Wiener Klinische Wochenschrift
Magdalena Hoffmann, Anna K Holl, Harald Burgsteiner, Philipp Eller, Thomas R Pieber, Karin Amrein
A patient's admission to an intensive care unit (ICU) has a significant impact on family members and other relatives. In order for them to be able to cope with such a stressful situation, the availability of appropriate understandable and accessible information is crucial. The information asymmetry between relatives and medical professionals may adversely affect satisfaction of relatives and their risk of subsequent anxiety, depression and stress symptoms. The aim of this study was therefore to understand which topics are most important to the relatives of ICU patients and to quantify the perceptions of medical professionals regarding the information needs of relatives...
August 9, 2018: Wiener Klinische Wochenschrift
Igor Grabovac, Sandra Haider, Eva Winzer, Ali Kapan, Karin E Schindler, Christian Lackinger, Thomas E Dorner
OBJECTIVE: To measure health effects in lay volunteers who made home visits consisting of social interaction, nutritional and physical exercise interventions to pre-frail and frail older people (trial registration, NCT01991639). METHODS: After baseline, participants were followed-up at 12 (V1) and 24 (V2) weeks. A one-repetition maximum (1-RPM) and handgrip were measured with the Concept2®DYNO and a dynamometer. The Physical Activity Scale for the Elderly was used to assess physical activity, and Food Frequency Questionnaire and the Mediterranean Diet Adherence Screener for nutrition...
August 9, 2018: Wiener Klinische Wochenschrift
Șerban Gligor, Ioana Mozoș
Smartphone addiction is one of the most common non-drug addictions, accompanied by negative effects, such as depression, anxiety, self-disclosure, impaired academic performance, family life and human relationships. The aim of the present study was to assess the prevalence of a predisposition to smartphone use disorder in university students and to investigate the associations between the intensity of mobile phone use and several variables. A total of 150 students, from 2 universities from Timisoara, were included in the study...
August 6, 2018: Wiener Klinische Wochenschrift
Bettina Kuppelwieser, Michael Berktold, Dorothea Orth-Höller, Cornelia Lass-Flörl
No abstract text is available yet for this article.
August 2, 2018: Wiener Klinische Wochenschrift
Andreas S Fazekas, Mei Aboulghaith, Ruxandra C Kriz, Matthias Urban, Marie-Kathrin Breyer, Robab Breyer-Kohansal, Otto-Chris Burghuber, Sylvia Hartl, Georg-Christian Funk
BACKGROUND: Non-invasive ventilation (NIV) is used to treat acute hypercapnic respiratory failure (AHRF) in patients with chronic obstructive pulmonary disease (COPD); however, long-term outcomes following discharge are largely unknown. This study aimed to characterize long-term outcomes and identify associated markers in patients with COPD after surviving the first episode of HRF requiring NIV. METHODS: This study retrospectively analyzed 122 patients, mean age 62 ± 8 years, 52% female and forced expiratory volume in 1 s (FEV1) predicted 30 ± 13%, admitted with an acute hypercapnic exacerbation of COPD and receiving a first-ever NIV treatment between 2000 and 2012...
July 31, 2018: Wiener Klinische Wochenschrift
Hannes F Alber, Kurt Huber
Duration and compostion of dual antiplatelet therapy has been increasingly changed within the past few years as also indicated in the firmer ESC guidelines. The current manuscript summarizes the most important changes in dual antiplatelet therapy as shown by a recent ESC position paper and offers quick insight into these new developments.
July 20, 2018: Wiener Klinische Wochenschrift
Peter Valent, Emir Hadzijusufovic, Thomas Grunt, Heidrun Karlic, Barbara Peter, Harald Herrmann, Gregor Eisenwort, Gregor Hoermann, Axel Schulenburg, Michael Willmann, Rainer Hubmann, Medhat Shehata, Edgar Selzer, Karoline V Gleixner, Thomas Rülicke, Wolfgang R Sperr, Brigitte Marian, Michael Pfeilstöcker, Hubert Pehamberger, Felix Keil, Ulrich Jäger, Christoph Zielinski
In 2008 the Ludwig Boltzmann Cluster Oncology (LBC ONC) was established on the basis of two previous Ludwig Boltzmann Institutes working in the field of hematology and cancer research. The general aim of the LBC ONC is to improve treatment of hematopoietic neoplasms by eradicating cancer-initiating and disease-propagating cells, also known as leukemic stem cells (LSC) in the context of leukemia. In a first phase, the LBC ONC characterized the phenotype and molecular aberration profiles of LSC in various malignancies...
July 13, 2018: Wiener Klinische Wochenschrift
Olaf Kahl
There are various arthropods (e.g. insects, chiggers, mites, ticks) that take one or more blood meals on terrestrial vertebrates in the course of their lifetime. Among them are ixodid ticks (Acari, Ixodidae), all of which are obligately hematophagous. Their parasitic lifestyle predestines them to act as transmitters or vectors of microparasites, often pathogenic to humans and/or domestic animals. The list of ixodid tick-borne pathogens is long, encompassing viruses, bacteria, protozoans, and nematodes. The present mini-review gives a brief overview of the most relevant biological attributes that make ixodid ticks very efficient vectors compared with other hematophagous arthropod taxa...
July 13, 2018: Wiener Klinische Wochenschrift
Christian Smolle, Gerald Sendlhofer, Janos Cambiaso-Daniel, Michaela Sljivich, Herwig Friedl, Lars-Peter Kamolz, Gernot Brunner
BACKGROUND: In Austria, elaborate definitions exist for the undesirable medical events side effect, adverse event, complication and medical malpractice. We aimed at investigating whether the official definitions for the abovementioned terms can be understood by a sample population representing a cross-section of the Austrian population. METHODS: In this study 1021 Austrian citizens were interviewed. Demographic parameters (age, gender, occupation, level of education, monthly income, number of inhabitants at place of residence) were assessed...
July 12, 2018: Wiener Klinische Wochenschrift
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No abstract text is available yet for this article.
September 2018: Wiener Klinische Wochenschrift
(no author information available yet)
No abstract text is available yet for this article.
September 2018: Wiener Klinische Wochenschrift
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