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Ideggyógyászati Szemle

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https://www.readbyqxmd.com/read/30113797/atypical-type-of-hirayama-disease-onset-of-proximal-upper-extremity
#1
Zeynep Özözen Ayas, Kıyasettin Asil
Hirayama disease is a rare, benign motor neuron disease. It has been proposed that the dura mater's posterior wall lacks sufficient elasticity in the lower cervical region and this causes the tense dura part to displace anteriorly upon flexion. The disease is described as involving unilateral upper extremity with a distal-onset. We reported weakness and atrophy of the proximal part of an extremity in a 45-year-old man who is diagnosed with Hirayama disease. Proximal onset is a rare type of Hirayama Disease...
July 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/30113796/can-high-uric-acid-levels-be-an-independent-risk-factor-for-acute-ischemic-stroke-due-to-large-artery-atherosclerosis
#2
Türkan Acar, Yesim Güzey Aras, Sıdıka Sinem Gül, Atılgan Bilgehan Acar
Background and purpose: Uric acid is a molecule that is known to act as a natural antioxidant in acute oxidative stress conditions such as acute ischemic stroke (AIS). Although there are several studies on the prognostic value of serum uric acid (UA) level, especially the AIS, its importance in ischemic stroke is still controversial. Our aim in this study is to investigate whether the serum UA level is an indicative biomarker in the large-artery atherosclerosis in the AIS etiology. Methods: Of the patients admitted to Sakarya University Training and Research Hospital Department of Neurology between January 2017 and November 2017, 91 hospitalized patients, who had AIS diagnosis and had their uric acid levels measured, were analyzed retrospectively...
July 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/30113795/novel-structured-mri-reporting-system-in-neonatal-hypoxic-ischemic-encephalopathy-issues-of-development-and-first-use-experiences
#3
Andrea Lakatos, Márton Kolossváry, Miklós Szabó, Ágnes Jermendy, Zsolt Bagyura, Péter Barsi, Gábor Rudas, Lajos R Kozák
Background and purpose: To develop an evidence-based, standardized structured reporting (SR) method for brain MRI examinations in neonatal hypoxic-ischemic encephalopathy (HIE) suitable both for clinical and research use. Methods: SR template development was based on comprehensive review of the pertinent literature with the basic sections and subdivisions of the template defined according to MRI sequences (both conventional and diffusion-weighted, MR-spectroscopy (MRS), and T2*-weighted imaging), and the items targeted on age-related imaging patterns of HIE...
July 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/30113794/-early-experience-with-minimal-invasive-treatment-of-thirty-one-thoracolumbar-injury-cases
#4
Ádám Varga, Róbert Veres, Péter Elek, Zoltán Mencser, Zoltán Rideg, Pál Barzó
The authors report on their experience with minimal invasive treatment of thirtyone thoracolumbar injury cases. The medical charts, radiological documentation (preop CT and MRI scans, postop CT scans at 3 and 6 months) were analysed retrospectively. All pedicle screws were inserted appropriately, there was no neurological deterioration or surgical site infection postoperatively. There were three cases of radiological loss of correction, however, these were clinically irrelevant. There were no screw loosening or implant failure observed...
July 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/30113793/-strategies-of-using-the-new-antiepileptic-drugs-for-epilepsy-in-adults
#5
REVIEW
János Nikl
The new antiepileptic drugs have not changed the basic pharmacological treatment principles of epilepsy, but they have given greater choice in focal and in generalized epilepsies as well. The new drugs are not necessarily more effective than traditional drugs, but they have favourable pharmacokinetic characteristics, fewer interactions and better adverse effect profile in the acute and chronic phase of the treatment. They generally show a lower teratogenicity risk than the standard antiepileptics, although carbamazepine, one of the standard drugs can be used and zonisamide, a new one must be avoid in pregnancy...
July 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/30113792/isocitrate-dehydrogenase-mutations-in-defining-the-biology-of-and-supporting-clinical-decision-making-in-glioblastoma
#6
REVIEW
Ferenc Kálovits, Márton Tompa, Ádám Nagy, Bernadette Kálmán
Background and purpose: Oncogenesis is related to a sequential accumulation of somatic mutations. Comprehensive characterizations of the genomic landscapes have been completed recently for several tumors, glioblastoma being among the first ones. Our own translational research studies have been focused on defining molecular subtypes of glioblastoma in the clinical setting because of an expected prognostic and therapeutic utility of the information. Somatic mutations in genes of the isocitrate dehydrogenase (IDH) enzyme family appear to be among the best-defined biomarkers that also influence tumor behavior and confer clinical utility...
July 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/30113791/-paradigm-shift-in-management-of-patients-with-vertigo-and-imbalance
#7
REVIEW
Andrea Mike, T László Tamás
Dizziness is one of the most common causes of medical visits. Management of the dizzy patient may be challenging both for the general practitioner, in emergency departments, and special clinics, as behind a seemingly homogeneous clinical presentation several very different etiologies may occur. Research of the last two century enriched our knowledge about physiology and pathophysiology of the vestibular system. Much knowledge is now available about the labyrinth being able to sense head motions and gravity, processing of afferent vestibular stimuli, reflectory oculomotor and postural control, or recovery of the vestibular system...
July 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29889464/what-is-the-real-effect-of-pregabalin-in-patients-with-diabetic-neuropathic-pain-do-patients-suffer-from-less-pain-or-do-they-less-care-about-it
#8
Cağdaş Erdoğan, Nedim Ongun, Selim Tümkaya, Hakan Alkan, Neşe Öztürk
Background and purpose: Depression and anxiety are frequent in patients with chronic diseases such as diabetic neuropathic pain. The pain seems to be more severe in patients in whom depressive findings accompanied pain symptoms. Pregabalin was reported to have positive effects on anxiety and depression. This brings out the question, whether the pain relief effect of pregabalin is due to its analgesic effect or to its effects on mood? The aim of this study is to find out whether the positive effect of pregabalin in patients with diabetic neuropathic pain is limited to its effect on pain...
May 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29889463/assessment-of-mental-health-of-carers-according-to-patient-stage-of-idiopathic-parkinson-s-disease
#9
Hülya Olgun Yazar, Tamer Yazar, Esra Yancar Demir, Soner Cankaya, Özgür Enginyurt
Background and purpose: In this study the aim was to collect data to assess the mental health of carers for patients with diagnosis of idiopathic Parkinson's disease (IPD) according to disease stage and to examine precautions to reduce the patient and disease load on carers. Methods: The study included 144 patients with staging according to modified Hoehn and Yahr criteria and 144 patient relatives who provided care support for patients every day, for some or all of the day, and who were over the age of 18 years and accepted participation in the research...
May 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29889462/retrospective-comparison-of-efficacy-of-levetiracetam-and-lacosamide-add-on-treatments-in-patients-with-partial-onset-seizure
#10
Türkan Acar, Yeşim Güzey Aras
Background and purpose: The study aims to retrospectively compare the efficacy of lacosamide (LCS) and levetiracetam (LEV) in add-on treatment in patients with partial-onset epilepsy. Methods: Patients who have been followed-up for at least one year due to diagnosis of partial epilepsy between September 2014 and December 2017 and who had no seizure control, despite using at least two antiepileptic monotherapies, and therefore undergone LEV or LCS add-on treatment were retrospectively reviewed...
May 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29889461/-assessment-of-health-related-quality-of-life-among-epileptic-patients-in-the-context-of-coping-strategies-and-subjective-disease-perception
#11
Daniella Kováts, Noémi Császár-Nagy, Vera Juhos, Viola Sallay, Judit Békés, Dániel Fabó, Anna Kelemen, Tamás Kurimay
Background and purpose: Psychosocial condition and life quality of epileptic patients are greatly determined by the existence of the disease-related comorbid disorders, like depression, anxiety, and the subjective disease perception, as well as the neuropsychological consequences of the seizures.It has been examined in patients living with epilepsy how subjective disease perception and coping strategies influence life quality, comorbid depression and the condition of anxiety. Methods: Study patients were asked to fill in a self-completion questionnaire, which examined their psychosocial condition (HADS, Beck Depression Scale), life quality (Qolie-31), coping strategies (FKV-LIS), and subjective disease perception (IPQ-R), as well as sociodemographic and disease variables...
May 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29889460/evaluation-of-ischemic-stroke-patients-with-systemic-cancer
#12
Ufuk Emre, Taskin Gunes, Irem Pinar, Furuzan Kokturk, Esengul Liman, Orhan Yağiz
Background and purpose: In cancer patients, an ischemic stroke can be seen as both a direct effect of cancer and a complication of treatment. This condition can negatively affect the follow-up and treatment of these patients. For this research, we aimed to evaluate the clinical features, stroke types and etiological features of ischemic stroke patients with histories of cancer or found to have cancer during the aetiological investigation. Methods: We retrospectively evaluated 100 patients (57 males, 43 females) who were hospitalized with acute stroke and determined to have the presence of cancer or a cancer history during the aetiological investigation between 2011 and 2016...
May 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29889459/-relationship-between-patent-foramen-ovale-and-cryptogenic-stroke-in-a-retrospective-hospital-based-study
#13
Péter Böjti, Noémi Eszter Bartha, Zsolt May, Dániel Bereczki, Szilvia Fülöp, Zoltán Szakács, Géza Szilágyi
Background and purpose: After routine workup, 23-25% of ischemic strokes etiology remains unknown, i.e. cryptogenic. However, according to international results pathogenic patent foramen ovale (PFO) reveals in 25% of these cases. Aim of our retrospective study to prove the substantial etiological role of PFO-related stroke (PFO-RS) in cryptogenic strokes (CS), and to identify age related differences in stroke etiology. Methods: All new ischemic strokes of 2014-2015 were classified by ASCOD (Atherosclerosis, Small-vessel disease, Cardiac pathology, Other, Dissection) phenotyping...
May 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29889458/is-stroke-indeed-a-monday-morning-disease
#14
András Folyovich, Anna Béres-Molnár K, Judit Gimesi-Országh, Lajos Katona, Dávid Biczó, Károly Vörös, Gábor Gőbl, András Ajtay, Dániel Bereczki
Background and purpose: The therapeutic time window of acute stroke is short. Decision on the use of intravenous thrombolysis is based on well-defined criteria. Any delay in the transport to a designated stroke centre decreases the odds of therapeutic success. In Hungary, the admission rate of stroke patients peaks on Monday, the number gradually decreasing by the end of the week. This phenomenon has long been suggested to be due to the lack of emergency care approach. According to the literature, however, returning to work following a holiday is a risk factor for acute stroke...
May 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29889457/-pharmacological-and-nonpharmacological-treatment-of-insomnias-with-regard-to-sleep-medicine
#15
REVIEW
Béla Faludi, Renáta Rozgonyi
Insomnia - one of the most prevalent sleep complain - has a great impact on the everyday life. Basically two different form of insomnia can be defined: the insomnia disorder and the co-morbid insomnias. To treat adequately determination of background pathology is essential, which is based on the help of Sleep Medicine Centers. According to the newest guidelines, the treatment of insomnia disorder is based on cognitive behavioural therapies followed by pharmaceutical intervention. In this review we provide the short description of cognitive behavioural therapies and basic principles of hypnotic drugs...
May 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29889473/a-rare-aetiology-of-stroke-myxomatous-aneurysm-caused-by-atrial-myxoma
#16
Erkan Acar, Zeynep Ozdemir, Hatem Hakan Selcuk, Eda Coban, Aysun Soysal
Atrial myxoma is a rare cause of stroke. In this report we present the case of a 52-year-old female patient who went to hospital suffering from a headache. Her neurological examination was normal except for a positive Babinski sign on the left. In the superolateral of the right, a Sylvian fissure consistent with a thrombosed aneurysm was detected using computerised tomography (CT). Diffusion MRI showed an acute infarction on the right MCA area. Transthorasic Echocardiography and ECG were normal. A -16×4 mm-sized fusiform perpendicular aneurysm on the M2 segment Sylvian curve of right MCA and a -6×4 mm-sized dissecting aneurysm on P3 segment of the left posterior cerebral artery (PCA) were observed in cerebral angiography...
March 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29889472/a-case-with-angiographic-demonstration-of-isolated-anterior-spinal-artery-occlusion
#17
Vasfiye Burcu Dogan, Batuhan Kara, Hakan Hatem Selcuk, Ayten Ceyhan Dirican, Ayhan Koksal
Anterior spinal artery syndrome (ASAS) is a rare syndrome which occurs due to thrombosis of anterior spinal artery (ASA) which supplies anterior two thirds of the spinal cord. A 27-year-old female patient was admitted to emergency clinic with sudden onset neck pain, sensory loss and weakness in proximal upper extremities which occurred at rest. Thrombophilia assessment tests were negative. Echocardiography was normal. Serum viral markers were negative. In cerebrospinal fluid (CSF) examination, cell count and biochemistry was normal, oligoclonal band was negative, viral markers for herpes simplex virus (HSV) type-1 and type-2, Brucella, Borrellia, Treponema pallidum, Tuberculosis were negative...
March 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29889471/-perinatal-stroke-from-symptoms-to-follow-up
#18
Eszter Vojcek, Márta Csécsei, Edina Flach, Gábor Rudas, Rózsa Gráf, Erzsébet Princzkel
Background and purpose: We aimed to analyze patient characteristics of term neonates with the diagnosis of stroke between 2006 and 2017 at the 3rd level Neonatal Intensive Care Unit of the Szent János Hospital. Methods: We conducted a retrospective and prospective analysis including 18 newborns with stroke. Presentation, imaging methods, etiology and clinical context were discussed. All patients had a follow-up at 2 years of age or later. Subject of the study - In the past 10 years 17 term born and one premature neonate born at 36 weeks of age were diagnosed with stroke in our unit...
March 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29889470/-schizotypal-traits-and-verbal-creativity
#19
Nikolett Fejes, Sándor Rózsa, Anita Must
Background and purpose: The relationship of schizophrenia and its milder, subclinical forms, with creativity has been in the centre of theoretical interest for decades, however, the systematic research of the topic only prevailed more recently. Purpose - Here we aimed to examine the connection between different schizotypal and non-schizotypal personality traits and verbal creativity in a nonclinical sample. We also investigated the correspondence of two schizotypy inventories, the Oxford-Liverpool Inventory of Feelings and Experiences and a special character configuration of the Temperament and Character Inventory associated with schizotypy...
March 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29889469/-changes-of-cognitive-functions-in-healthy-aging
#20
Dóra Juhász, Dezső Németh
Background and purpose: Introduction - Mental health has crucial role in our life. Cognitive changes or decline can lead to many difficulties in daily routine of older people (e.g. organization of daily activities), which can, consequently, influence their well-being. Therefore it is an important question, which cognitive abilities are affected by age-related decline. Methods: In our study we aimed to investigate the changes of cognitive abilities in healthy older adults between 61 and 85 years of age compared to the performance of younger adults...
March 30, 2018: Ideggyógyászati Szemle
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