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Ideggyógyászati Szemle

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https://www.readbyqxmd.com/read/29465902/-the-facets-of-creativity-in-the-light-of-bipolar-mood-alterations
#1
Réka Szakács
The link between creativity, as the highest expression form of human achievement, and bipolar disorder came into focus of scientific investigations and research. Accomplished writers, composers and visual artists show a substantially higher rate of affective disorders, prodominantly bipolar mood disorders, comparing to the general population. Then again, patients afflicted with bipolar II subtype (hypomania and depression), as well as persons presenting the mildest form of bipolar mood swings (cyclothymia) possess higher creative skills...
January 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29465901/association-of-cardiovascular-risk-factors-and-parkinson-s-disease-case-control-study-in-south-east-hungary
#2
Mária Markó-Kucsera, László Vécsei, Edit Paulik
Background and purpose: Parkinson's disease (PD) has the second highest incidence among neurodegenerative diseases in the world population. The study aimed to investigate the presence of some cardiovascular risk factors - dyslipidemia, diabetes, and hypertension - in PD patients and to compare their risk with non-PD population in South East Hungary. Methods: A case-control study was conducted at the Department of Neurology, University of Szeged, Hungary. The study included 1299 subjects out of which 620 patients were identified as cases of diagnosed PD and 679 as controls...
January 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29465900/alteration-of-mean-platelet-volume-in-the-pathogenesis-of-acute-ischemic-stroke-cause-or-consequence
#3
Zeynep Özözen Ayas, Ufuk Can
Background and purpose: Platelets have a crucial role on vascular disease which are involved in pathogenesis of ischemic stroke. Platelet size is measured as mean platelet volume (MPV) and is a marker of platelet activity. Platelets contain more dense granules as the size increases and produce more serotonin and tromboglobulin (b-TG) than small platelets. In this study, the alteration of MPV values were investigated in patients with acute stroke, who had MPV values before stroke, during acute ischemic stroke and 7 days after the stroke...
January 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29465899/electroclinical-and-prognostic-characteristics-of-epilepsy-patients-with-photosensitivity
#4
Hülya Olgun Yazar, Günay Gül, Tamer Yazar, Fulya Eren, Demet-Yandım Kuscu, Dursun Kirbas
Background and purpose: Epilepsy with photosensitivity (PSE) is one of the reflex epilepsy types with pathophysiology still unexplained. In our study we aimed to evaluate the clinical, electroencephalogram (EEG) and prognosis of patients with PSE diagnosis. Methods: A total of 44 patients with PSE diagnosis according to international classification were included in this retrospective and cross-sectional study. The age, gender, syndrome, clinical and EEG characteristics of patients, and treatment response were investigated...
January 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29465898/functional-neurotoxicity-and-tissue-metal-levels-in-rats-exposed-subacutely-to-titanium-dioxide-nanoparticles-via-the-airways
#5
Tamara Horváth, Tünde Vezér, Gábor Kozma, András Papp
Background and purpose: Nanoparticles of titanium dioxide are suspected neurotoxic agents and have numerous applications possibly resulting in human exposure by several ways including inhalation. In the present work, rats were exposed to spherical TiO2 nanoparticles of two different sizes by the intratracheal route. It was investigated how the neuro-functional alterations, detected by electrophysiological and behavioral methods, were related to the concentration of Ti in the tissue samples and what the influence of the size of the NPs was...
January 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29465897/-effects-of-nasal-provocation-with-a-single-dose-allergen-on-the-explicit-and-implicit-memory-of-physically-active-and-inactive-patients-with-ragweed-allergy
#6
Margaréta Tokodi, Eszter Csábi, Ágnes Kiricsi, Rebeka Schultz, Andor Molnár H, László Rovó, Zsolt Bella
Background and purpose: Allergy is an endemic disease and has a considerable impact on the quality of life. This study aimed to measure the effect of active allergic rhinitis on memory functions of physically active and inactive patients with ragweed allergy. Methods: Memory functions were assessed before and after allergen exposure. Participants in both groups were provoked nasally with 30 IR/mL ragweed allergen in each nostril. Explicit memory was measured with story-recalling and implicit memory was investigated with reaction time task...
January 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29465896/insights-into-the-structure-and-function-of-the-hippocampal-formation-relevance-to-parkinson-s-disease
#7
REVIEW
Orsolya Györfi, Helga Nagy, Magdolna Bokor, Szabolcs Kéri
The link between the hippocampus and declarative memory dysfunctions following the removal of the medial temporal lobe opened unexplored fields in neuroscience. In the first part of our review, we summarized current theoretical frameworks discussing the role of hippocampus in learning and memory. Several theories are highlighted suggesting that the hippocampus is responsible for assembling stimulus elements into a unitary representation that later can be utilized to simulate future events. The hippocampal formation has been implicated in a growing number of disorders, from neurodegenerative diseases to atypical cognitive ageing and depression...
January 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29465895/-clinical-neurophysiological-methods-in-diagnosis-and-treatment-of-cerebrovascular-diseases
#8
REVIEW
Ildikó Nagy, Dániel Fabó
Neurophysiological methods are gaining ground in the diagnosis and therapy of cerebrovascular disease. While the role of the EEG (electroencephalography) in the diagnosis of post-stroke epilepsy is constant, quantitative EEG para-meters, as new indicators of early efficiency after thrombolysis or in prognosis of patient's condition have proved their effectiveness in several clinical studies. In intensive care units, continuous EEG monitoring of critically ill patients became part of neurointenzive care protocols...
January 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29465894/four-cases-of-gabab-receptor-encephalitis
#9
Mónika Szőts, Morten Blaabjerg, Daniel Kondziella, Mihály Herceg, Péter Diószeghy, Gábor Bajzik, Tímea Berki, Endre Kálmán, Ferenc Nagy, Zsolt Illés
GABAB receptor (gamma-aminobutyric acid type B receptors - GABABR) encephalitis is a rare manifestation of autoimmune encephalitides. We report four cases - including the first two Hungarian patients - with some peculiar features. One patient developed subacute disorientation and almost complete loss of short-term memory, but no epilepsy. Without immunotherapy, his memory spontaneously improved up to mild cognitive impairment in six weeks. GABABR antibodies persisted in his serum, and 18 months later, FDG-PET detected abnormal mediastinal lymph nodes and small cell lung cancer (SCLC)...
July 30, 2016: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29465893/association-of-anterior-thoracic-meningocele-and-azygos-lobe-of-the-lung
#10
Fatih Ersay Deniz, Atilla Senayli, Unal Bicakci
Here we report an anterior thoracic meningocele case. Twoyears- old female patient was presented with kyphosis. Azygos lobe of the lung was also demonstrated during radiological studies. Posterolateral thoracotomy incision and extralpeural approach was performed for excision of the anterior meningocele to untether the cord. Although both anomalies are related to faulty embryogenesis and it is well known that faulty embryogenesis may also reveal coexisting abnormalities, we could not speculate a common mechanism for anterior thoracic meningocele and azygos lobe of the lung association...
July 30, 2016: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29465892/burning-mouth-syndrome-evaluation-of-clinical-and-laboratory-findings
#11
Gulistan Halac, Pinar Tekturk, Saliha Eroglu, Mehmet Ali Cikrikcioglu, Ozlem Cimendur, Elif Kilic, Talip Asil
Background and purpose: Burning mouth syndrome is a chronic and persistent painful condition characterized by burning sensation in the oral mucosa. We investigated the etiological factors of patients presented with the history of burning in the mouth who admitted our outpatient clinics over the 8-years period and who had no underlying identifiable local factors. We also tried to determine their demographic and clinical characteristics. Our aim was to investigate the association between burning mouth and psychiatric disorders such as depression and anxiety, chronic diseases like diabetes mellitus (DM) and other laboratory studies in patients complaining of solely burning in the mouth...
July 30, 2016: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29465891/gray-matter-atrophy-in-presymptomatic-huntington-s-patients
#12
András Király, Zsigmond Tamás Kincses, Nikoletta Szabó, Eszter Tóth, Gergő Csete, Péter Faragó, László Vécsei
Background and purpose: Background - Huntington's disease is a progressive disease in which neurodegeneration is on-going from the early presymptomatic phase. Development of sensitive biomarkers in this presymptomatic stage that are able to monitor the disease progression and test the efficacy of putative neuroprotective treatments are essential. Methods: Methods - Seven presymptomatic Huntington mutation carriers and ten age-matched healthy controls were recruited...
July 30, 2016: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29465890/-the-effect-of-anesthesia-on-cognitive-functions
#13
Tímea Bocskai, Kázmér Karádi, András Burián, Norbert Kovács, Lajos Bogár, László Lujber
Aim of the study - General anesthetics, arterial hypotension and hypoxia developing during anesthesia may result in impaired memory and a decline in other abilities (such as attention, concentration, linguistic and writing abilities). Our aim was to detect changes in cognitive functions due to surgery and anesthesia with controlled arterial hypotension. Materials and methods - We studied combined and intravenous anesthesia detecting pre-and postoperative cognitive functions, intraoperative haemodynamic parameters, demographic data, other data of case history and surgical data...
July 30, 2016: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29465889/-transthyretin-familial-amyloid-polyneuropathy-three-hungarian-cases-with-rare-mutations-his88arg-and-phe33leu
#14
Anita Csillik, Zoltán Pozsonyi, Krisztina Soós, István Balogh, Imre Bodó, Zsuzsanna Arányi
Introduction - Transthyretin familial amyloid polyneuropathy is a rare autosomal dominant progressive systemic disesase of adults caused by endoneural amyloid deposition due to point mutations of the transthyretin gene. It is the most severe form among hereditary polyneuropathies, being fatal within 10 years if left untreated. The disease is underdiagnosed, the late onset forms (above the age of 50) being probably more widespread than previously thought. Early diagnosis is essential as the early introduction of causal therapy (tafamidis) slows progression and prolongs survival...
July 30, 2016: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29465888/-angioneuritic-edema-in-ischaemic-stroke-patients-treated-with-rt-pa
#15
Rita Lovász, Attila Sas, Tibor Kollár, Edina Petercsák, István Fekete, Erika Bilinszki, Attila Valikovics
Data of our 254 patients who were treated with rt-PA between 1st of Jan, 2011 and 31st of Dec, 2014 were processed. We focused on angioneurotic oedema as allergic complication of thrombolysis which caused life threatening respiratory obstruction in two cases. We describe these two patients' history. Out of 254 patients six (2.3%) suffered angioneurotic edema caused respiratory obstruction in two (0.90%) cases. This occurrence is approximately 1.3-5.1% in literature. Five, out of six patients who suffered from angioneurotic oedema, had been treated with ACE inhibitors or ARB before...
July 30, 2016: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29465887/-the-role-of-zonisamide-in-the-management-of-pediatric-partial-epilepsy
#16
REVIEW
Beáta Rosdy, Katalin Kollár, Judit Móser, Mónika Mellár
In our review we discuss the group of approved antiepileptic drugs for children in Hungary. We cite the results of the review conducted by the International League Against Epilepsy on antiepileptic drug efficacy and effectiveness as initial monotherapy for newly diagnosed epileptic seizures and syndromes in pediatric age group. 25% of pediatric epilepsy is therapy resistant, so we further need new drugs, which must be investigated according to the rules of the European Medicine Agency. The ethical dilemmas of childhood drug studies lead to the situation that the new antiepileptic drugs, approved as monotherapy in adult epilepsies, are in the majority just in add-on regimen tested in pediatric patients...
July 30, 2016: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29465886/syndrome-of-trephined-underestimated-and-poorly-understood-complication-after-decompressive-craniectomy
#17
REVIEW
József Láng, Mario Ganau, Lara Prisco, Krisztina Bozsik, Péter Banczerowski
Decompressive craniectomy (DC) is still a matter of debate, with a numerous complications as expansion of haemorrhagic contusions, external cerebral herniation, subdural hygromas, post-traumatic hydrocephalus (HC). The often overlooked "syndrome of the trephined" (ST) as a delayed complication of DC also known as sinking skin flap sy initially described in 1939.ST is characterised by the neurological changes associated with alteration of the pressure/volume relationship between intracranial pressure (ICP), volume of cerebrospinal fluid (CSF), blood, and brain tissue in patients with large bone defects...
July 30, 2016: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29465885/-meningioma-and-pregnancy
#18
REVIEW
János Bencze, Gréta Varkoly, Tibor Hortobágyi
Meningiomas are one of the most frequent primary intracranial tumours, representing one-third of all intracranialneoplasms. The vast majority of meningiomas are histologically benign, but recurrence and progression is quite frequent. They occur usually between the 6th and 7th decade, the female/male ratio is 3:2. Although rare in pregnancy, when occurring, they can cause serious, life-threatening complications due to rapid growth and unfavourable localisation. There are two dominant hypothesis explaining rapid growth in pregnancy: the role of hormonal effects and hemodynamic changes...
July 30, 2016: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/27468611/-closure-of-nasocranial-fistulas-with-bath-plug-technique-and-multilayer-reconstruction
#19
Zalán Piski, András Büki, Nelli Nepp, Andráas Burián, Péter Révész, Imre Gerlinger
BACKGROUND AND PURPOSE: In case of dehiscenses developing on the anterior scull base, complete closure resulting in the cessation of the communication between the nasal cavity and the intracranial space is mandatory as soon as possible, in order to prevent serious complications. With the development of the endoscopic techniques, the endonasal management for the reconstruction has become available in recent decades. METHODS: We aim to present the reconstruction techniques applied in our department in the cases of two patients recently operated at our institute...
March 30, 2016: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/27468610/-effect-of-instrumental-surgical-fusion-on-the-quality-of-life-in-degenerative-spondylolisthesis
#20
Enikő Sáró, Ferenc Misik, Péter Banczerowski
OBJECTIVE: There is no internationally accepted guideline for treatment of spondylolisthesis in the literature, otherwise this degenerative disease has great social and economical impact. There is no hungarian study examining the efficacy of instrumented fusion procedure in surgical treatment of spondylolisthesis. In current study we examined the effectiveness of fusion technique focusing on the impact of quality of life. METHODS: Between 1st January, 2011 and 30th June, 2012 we examined a group of patients--who were operated on by instrumented fusion technique because of spondylolisthesis--, in the National Institute of Clinical Neurosciences, using the Oswestry Low Back Disability Questionnaire...
March 30, 2016: Ideggyógyászati Szemle
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