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Arquivos de Gastroenterologia

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https://www.readbyqxmd.com/read/28327826/efficacy-of-tacrolimus-for-induction-of-remission-in-patients-with-moderate-to-severe-ulcerative-colitis-a-systematic-review-and-meta-analysis
#1
Juan Lasa, Pablo Olivera
BACKGROUND: There is evidence that shows that calcineurin inhibitors may be useful for the treatment of severe ulcerative colitis. However, evidence regarding the efficacy of tacrolimus for remission induction in this setting is scarce. OBJECTIVE: To develop a systematic review on the existing evidence regarding the clinical efficacy of tacrolimus for the induction of remission in patients with moderate-to-severe ulcerative colitis. METHODS: A literature search was undertaken from 1966 to August 2016 using MEDLINE, Embase, LILACS and the Cochrane Library...
March 16, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28327825/genotype-association-gstm1-null-and-gastric-cancer-evidence-based-meta-analysis
#2
Rívian Xavier Ribeiro, Cícera Isabella Leão Leite Nascimento, Antonio Márcio Teodoro Cordeiro Silva
BACKGROUND: Gastric cancer is the fourth most common cancer in men and the sixth among women, except for non-melanoma skin tumors, in Brazil. Epidemiological evidences reveal the multifactorial etiology of this cancer, highlighting risk factors such as: infection by the bacterium Helicobacter pylori, advanced age, smoking, chronic alcohol abuse, eating habits and genetic polymorphisms. Considering the context of genetic polymorphisms, there is the absence of the GSTM1 gene. The lack of GSTM1 function to detoxify xenobiotics and promote defense against oxidative stress leads to increased DNA damage, promoting gastric carcinogenesis...
March 16, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28327824/screening-of-wild-fruit-trees-with-gastroprotective-activity-in-different-experimental-models
#3
Luciane Angela Nottar Nesello, Adriana Campos, Roseane Leandra da Rosa, Sérgio Faloni de Andrade, Valdir Cechinel
BACKGROUND: Given the increase of people with gastrointestinal disorders, the search for alternative treatments with fewer side effects is vital, as well as the demand for food or plants that can help protect the stomach. OBJECTIVE: The aim of this study was to evaluate the gastroprotective action of the extracts of wild fruit trees of Myrcianthes pungens (guabiju); Inga vera Willd. (ingá-banana) and Marlierea tomentosa Cambess. (guarapuruna) in in vivo pharmacological models...
March 16, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28327823/ex-vivo-model-of-rabbit-intestinal-epithelium-applied-to-the-study-of-colonization-by-enteroaggregative-escherichia-coli
#4
Ricardo Luís Lopes Braga, Ana Claudia Machado Pereira, Paula Azevedo Dos Santos, Angela Corrêa Freitas-Almeida, Ana Cláudia de Paula Rosa
BACKGROUND: The diarrheal syndrome is considered a serious public health problem all over the world and is considered a major cause of morbidity and mortality in developing countries. The high incidence of enteroaggregative Escherichia coli in diarrheal syndromes classified as an emerging pathogen of gastrointestinal infections. After decades of study, your pathogenesis remains uncertain and has been investigated mainly using in vitro models of adhesion in cellular lines. OBJECTIVE: The present study investigated the interaction of enteroaggregative Escherichia coli strains isolated from childhood diarrhea with rabbit ileal and colonic mucosa ex vivo, using the in vitro organ culture model...
March 16, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28327822/impact-of-roux-en-y-gastric-bypass-surgery-rygb-on-metabolic-syndrome-components-and-on-the-use-of-associated-drugs-in-obese-patients
#5
Vilma Maria Junges, Jarbas Marinho Cavalheiro, Eliana Franzoi Fam, Vera Elizabeth Closs, João Feliz Moraes, Maria Gabriela Gottlieb
BACKGROUND: The prevalence of obesity and metabolic syndrome is increasing worldwide and both behavior modification and drug therapy have low adherence. Gastric bypass has shown effective results in both reducing weight and improving comorbidities. OBJECTIVE: To evaluate the impact of Roux-en-Y Gastric Bypass Surgery (RYGB) on both metabolic syndrome components and the use of associated drugs in obese patients. METHODS: Historical cohort of patients subjected to Roux-en-Y Gastric Bypass Surgery (RYGB) between January 2007 and March 2014 in a private clinic...
March 16, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28273277/esophageal-motility-in-men-and-women-evaluated-by-high-resolution-manometry
#6
Tarciana Vieira Costa, Roberto Oliveira Dantas
BACKGROUND: Esophageal motility has been described in the literature as having differences between men and women. Most of these investigations use the water perfusion method for esophageal manometry. In this investigation the esophageal motility of men and women was compared with high-resolution manometry of the esophagus. OBJECTIVE: To compare the esophageal motility of men and women with the high-resolution manometry method for esophageal manometry, performed in the sitting position...
February 23, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28273276/sim-brasil-study-women-s-gastrointestinal-health-gastrointestinal-symptoms-and-impact-on-the-brazilian-women-quality-of-life
#7
Ana Paula Wolf Tasca Del'arco, Pamela Magalhães, Flávio Antônio Quilici
BACKGROUND: Gastrointestinal symptoms seem to affect more women, due to hormonal and emotional issues, impacting the quality of life. The emotional state can affect the bowel functioning through a bidirectional communication system between the gut and the brain involving the neuroendocrine system. Altered bowel functioning and gastrointestinal symptoms can alter quality of life. OBJECTIVE: The SIM study aimed to describe, characterize and quantify gastrointestinal symptoms reported by Brazilian women, their causes, feelings and impact...
February 23, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28273275/assessing-the-sleep-quality-and-depression-anxiety-stress-in-irritable-bowel-syndrome-patients
#8
Nadieh Baniasadi, Mohammad Moein Dehesh, Elham Mohebbi, Mahdy Hayatbakhsh Abbasi, Zohreh Oghabian
BACKGROUND: Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders with chronic abdominal pain and altered bowel habit without any organic reason. Sleep disorders may be associated to IBS. OBJECTIVE: We aimed to assess sleep disturbances and depression-anxiety-stress in IBS patients. METHODS: In this analytical cross sectional study from November 2013 to May 2014, A total of 123 IBS patients were recruited by simple random sampling...
February 23, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28273274/effects-of-probiotic-intake-on-intestinal-bifidobacteria-of-celiac-patients
#9
Flávia Martinello, Camila Fontana Roman, Paula Alves de Souza
BACKGROUND: Healthy individuals exhibit a significantly higher concentration of faecal bifidobacteria in comparison to celiac patients. Even though there are potential benefits in probiotic usage, they have been little explored as an adjunctive therapy in celiac disease. OBJECTIVE: This study aimed at the comparison of faecal bifidobacteria concentration and pH among celiac patients and healthy subjects before and after the daily intake of 100 g of yogurt containing probiotic for a thirty-day period...
February 23, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28273273/prevalence-of-small-intestine-bacterial-overgrowth-in-patients-with-gastrointestinal-symptoms
#10
Carolina Piedade Martins, Caio Henrique Amorim Chaves, Maurício Gustavo Bravim de Castro, Isabel Cristina Gomes, Maria do Carmo Friche Passos
BACKGROUND: Small intestine bacterial overgrowth is a heterogeneous syndrome characterized by an increase in the number and/or the presence of atypical microbiota in the small intestine. The symptoms of small intestine bacterial overgrowth are unspecific, encompassing abdominal pain/distension, diarrhea and flatulence. Due to the increased cost and complexity for carrying out the jejunal aspirate, the gold standard for diagnosis of the syndrome, routinely the hydrogen (H 2 ) breath test has been used, utilizing glucose or lactulose as substrate, which is able to determine, in the exhaled air, the H 2 concentration produced from the intestinal bacterial metabolism...
February 23, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28198916/relationship-between-nutritional-status-and-the-clinical-outcomes-of-patients-with-and-without-neoplasms-according-to-multiple-correspondence-analysis
#11
Vânia Aparecida Leandro-Merhi, José Luiz Braga de Aquino
BACKGROUND: For many years, many studies have reported undesirable outcomes that may occur during the hospital stay of patients diagnosed with malnutrition or even at some nutritional risk. OBJECTIVE: To investigate the relationship between nutritional status and clinical outcomes during hospital stay using the multiple correspondence analysis technique. METHODS: This cross-sectional study included 600 patients with and without neoplasms. The following data were collected: subjective global assessment, nutritional indicators, nutritional risk screening, anthropometric data (body mass index (BMI), mid-upper arm circumference (MUAC), mid-upper arm muscle circumference (MUAMC), triceps skinfold thickness (TST), recent weight loss (RWL)), and habitual energy intake (HEI/ER <75%)...
February 13, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28198915/personality-traits-anger-and-psychiatric-symptoms-related-to-quality-of-life-in-patients-with-newly-diagnosed-digestive-system-cancer
#12
Noemi Peres Honorato, Luciene Vaccaro de Morais Abumusse, Daniel Pereira Coqueiro, Vanessa de Albuquerque Citero
BACKGROUND: The presence of psychiatric symptoms, anger, and personality characteristics are factors that affect the quality of life of newly diagnosed digestive system cancer patients. OBJECTIVE: This study aims to identify which stable characteristics of the individual's personality interfere with quality of life, even when reactive emotional characteristics of falling ill are controlled. METHODS: A cross-sectional study was performed at the Oncology Clinic ( Hospital das Clínicas ), Marília/SP, Brazil, in which 50 adult patients with digestive system cancer and diagnosed less than 6 months answered the State-Trait Anger Expression Inventory, Temperament and Character Inventory, Hospital Anxiety and Depression Scale and WHOQOL-BREF...
February 13, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28198914/action-of-vitamin-e-on-experimental-severe-acute-liver-failure
#13
Fabiano Moraes Miguel, Elizângela Gonçalves Schemitt, Josieli Raskopf Colares, Renata Minuzzo Hartmann, Maria Isabel Morgan-Martins, Norma Possa Marroni
BACKGROUND: Severe Acute Liver Failure (ALF) is a life-threatening clinical syndrome characterized by hepatocyte necrosis, loss of hepatic architecture, and impairment of liver functions. One of the main causes of ALF is hepatotoxicity from chemical agents, which damage hepatocytes and result in increase of reactive oxygen species. The vitamin E isoform is the one with the strongest biological antioxidant activity. OBJECTIVE: To evaluate the antioxidant effect of vitamin E in this ALF model...
February 13, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28198913/body-composition-in-patients-with-crohn-s-disease-and-ulcerative-colitis
#14
Ivi Ribeiro Back, Sonia Silva Marcon, Natalia Moreno Gaino, Daniela Salate Biagioni Vulcano, Mariana de Souza Dorna, Ligia Yukie Sassaki
BACKGROUND: The nutritional status of individuals with inflammatory bowel diseases is directly related to the severity of the disease and is associated with poor prognosis and the deterioration of immune competence. OBJECTIVE: To assess the nutritional status and the body composition of outpatients with inflammatory bowel diseases. METHODS: A cross-sectional study was conducted with clinical and nutritional assessment of patients with Crohn's disease and ulcerative colitis...
February 13, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28198912/inflammatory-bowel-disease-outpatient-treatment-profile
#15
Rachael Miranda Dos Santos, Ana Teresa Pugas Carvalho, Kelly Dos Santos Silva, Selma Petra Chaves Sá, Aparecida Helena Dos Santos, Millene Ramos Sandinha
BACKGROUND: Crohn's disease and ulcerative colitis are the two major forms of inflammatory bowel disease. The incidence and prevalence of both conditions have increased and are progressively increasing. These diseases are frequently recurrent and clinically highly severe. In Brazil, the lack of epidemiological data related to such diseases has left these patients in a vulnerable state and contributed to increased morbidity. OBJECTIVE: To describe the profiles of patients with inflammatory bowel disease treated in an outpatient service in Brazil...
February 13, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28079246/is-total-lymphocyte-count-related-to-nutritional-markers-in-hospitalized-older-adults
#16
Vânia Aparecida Leandro-Merhi, Vitória Negri Bráz, José Luis Braga de Aquino
BACKGROUND: - Older patients are commonly malnourished during hospital stay, and a high prevalence of malnutrition is found in hospitalized patients aged more than 65 years. OBJECTIVE: - To investigate whether total lymphocyte count is related to other nutritional markers in hospitalized older adults. METHODS: - Hospitalized older adults (N=131) were recruited for a cross-sectional study. Their nutritional status was assessed by the Nutritional Risk Screening (NRS), anthropometry, and total lymphocyte count...
January 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28079245/gastric-and-jejunal-histopathological-changes-in-patients-undergoing-bariatric-surgery
#17
COMPARATIVE STUDY
Rosemary Simões Nomelini Rodrigues, Élia Cláudia de Souza Almeida, Júverson Alves Terra, Lucinda Calheiros Guimarães, Ana Cristina da Rocha Duque, Renata Margarida Etchebehere
BACKGROUND: - Morbid obesity is a multifactorial disease that is increasingly treated by surgery. OBJECTIVE: - To evaluate gastric histopathological changes in obese, and to compare with patients who underwent gastrojejunal bypass and the jejunal mucosa after the surgery. METHODS: - This is an observational study performed at a tertiary public hospital, evaluating endoscopic biopsies from 36 preoperative patients and 35 postoperative. RESULTS: - In the preoperative group, 80...
January 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28079244/preoperative-multidisciplinary-program-for-bariatric-surgery-a-proposal-for-the-brazilian-public-health-system
#18
Elinton Adami Chaim, José Carlos Pareja, Martinho Antonio Gestic, Murillo Pimentel Utrini, Everton Cazzo
BACKGROUND: - Bariatric surgery has become the gold standard treatment for morbid obesity, but access to surgery remains difficult and low compliance to postoperative follow-up is common. To improve outcomes, enable access and optimize follow-up, we developed a multidisciplinary preoperative approach for bariatric surgery. OBJECTIVE: - To determine the impact of this program in the outcomes of bariatric surgery in the Brazilian public health system. METHODS: - A prospective evaluation of the individuals who underwent a preoperative multidisciplinary program for bariatric surgery and comparison of their surgical outcomes with those observed in the prospectively collected historical database of the individuals who underwent surgery before the beginning of the program...
January 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28079243/serum-levels-of-vitamin-a-visual-function-and-ocular-surface-after-bariatric-surgery
#19
Luana Paula Nogueira de Araújo Brandão, Lucio Vilar, Bernardo Menelau Cavalcanti, Pedro Henrique Amorim Brandão, Tiago Eugênio Faria E Arantes, Josemberg Marins Campos
BACKGROUND: - Bariatric surgery is the most effective treatment for severe obesity, but the surgery increases the risk of developing nutritional deficiencies, such as vitamin A deficiency. In human metabolism, vitamin A plays a role in vision. OBJECTIVE: - To evaluate serum vitamin A, visual function and ocular surface of patients undergoing bariatric surgery. METHODS: - A cross-sectional and analytical study was conduced with 28 patients undergoing bariatric surgery for at least 6 months...
January 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28079242/application-of-baros-questionnaire-in-obese-patients-undergoing-bariatric-surgery-with-2-years-of-evolution
#20
Caetano de Queiroz, José Afonso Sallet, Pedro Gabriel Melo DE Barros E Silva, Luzia da Gloria Pereira de Sousa Queiroz, Jélis Arenas Pimentel, Paulo Clemente Sallet
BACKGROUND: -In recent decades, the high prevalence of obesity in the general population has brought serious concerns in terms of public health. Contrarily to conventional treatment involving dieting and physical exercising, often ineffective in generating long term results, bariatric opera-tions have been an effective method for sustained weight loss in morbidly obese individuals. The Bariatric Analysis and Reporting Outcome System (BAROS) is an objective and recognized system in the overall evaluation of results after bariatric surgery...
January 2017: Arquivos de Gastroenterologia
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