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Arquivos de Gastroenterologia

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[This corrects the article doi: 10.1590/S0004-28032016000300001].
October 2016: Arquivos de Gastroenterologia
Sabrina Alves Fernandes, Silvia Bona, Carlos Thadeu Schmidt Cerski, Norma Possa Marroni, Claudio Augusto Marroni
Background: The inherent complications of cirrhosis include protein-calorie malnutrition and micronutrient deficiencies.Changes in taste are detrimental to the nutritional status, and the mechanism to explain these changes is not well documented in the cirrhotic patients. Objective: To evaluate the taste buds of cirrhotic rats. Methods: Fourteen male Wistar rats were evaluated. After 16 weeks, the liver was removed to histologically diagnose cirrhosis, and blood was collected to perform liver integrity tests...
October 2016: Arquivos de Gastroenterologia
Luiz Gustavo de Quadros, Roberto Luiz Kaiser, Manoel Dos Passos Galvão, Josemberg Marins Campos, Marcelo Falcão de Santana, Alvaro Antonio Bandeira Ferraz
Background: A multitude of endoscopic findings post-gastric bypass procedures have been previously reported in the literature, but to our knowledge, no present rules exist that could guide clinicians regarding which findings should be actively sought, once an initial finding is identified. Objective: To identify co-occurrence patterns among endoscopic findings of patients having undergone past gastric bypass procedure. Methods: Our registry involves all consecutive patients undergoing an upper endoscopic evaluation after a gastric bypass procedure...
October 2016: Arquivos de Gastroenterologia
Janaína Guilhem Muniz, Vera Lucia Sdepanian, Ulysses Fagundes
Background: Celiac disease is a permanent intolerance induced by gluten, which is expressed by T-cell mediated enteropathy, and has a high prevalence in the general population. There is evidence of a strong genetic predisposition to celiac disease. Objective: To determine the prevalence of genetic markers HLA-DQ2 and HLA-DQ8 in blood donors from São Paulo and measure human recombinant tissue transglutaminase antibody IgA class in HLA-DQ2 and HLA-DQ8 positive donors...
October 2016: Arquivos de Gastroenterologia
Ludmilla S Camargo, Jonas Ac Silveira, José Aac Taddei, Ulysses Fagundes
Background: Allergic proctocolitis is a disease that affects infants in the first months. The change in feed is the primary factor for clinical improvement and maintenance of the nutritional status of the infant. Objective: Study the anthropometric evolution of infants with allergic proctocolitis at diagnosis and 1 to 6 months after nutritional intervention. Methods: A retrospective cohort of infants with allergic proctocolitis diagnosis followed at the Pediatric Gastroenterology Institute of São Paulo (IGASTROPED), Brazil...
October 2016: Arquivos de Gastroenterologia
Júlio Rocha Pimenta, Alexandre Rodrigues Ferreira, Paulo Fernando Souto Bittencourt, Camilo Brandão de Resende, Eleonora Druve Tavares Fagundes, Isabela Maria Lopes da Silva
Background: The efficacy of nonselective β-blocker and endoscopic procedures, such as endoscopic variceal ligation, as primary prophylaxis of variceal hemorrhage in cirrhotic adults was demonstrated by numerous controlled trials, but in pediatric population, few are the number of studies. Objective: The objective of this study is to evaluate the primary prophylaxis with β-blocker in cirrhotic children and adolescents with portal hypertension. Methods: This is a cohort study encompassing 26 cirrhotic patients...
October 2016: Arquivos de Gastroenterologia
Flavia Feijó Nunes, Lílian Bassani, Sabrina Alves Fernandes, Maria Eugênia Deutrich, Bianca Coccaro Pivatto, Cláudio Augusto Marroni
Background: Patients with liver disease often present protein-energy malnutrition. The assessment of food intake is very important in the investigation regarding the "health-disease" process. Objective: To assess dietary intake of cirrhotic patients through food record during 3 days, correlating it with the nutritional status of the patient and the stage of the disease. Methods: Cirrhotic outpatients from the Santa Casa de Misericórdia Hospital, RS, Brazil, were assessed...
October 2016: Arquivos de Gastroenterologia
Giórgia de Souza Marasca, André Luiz Machado, Nélson Alexandre Kretzmann, Adaliany Cecília da Silva Souza, Angelo Alves de Mattos, Dimas Kliemann, Cristiane Valle Tovo, Ana Beatriz Gorini da Veiga
Background: Due to the high prevalence of co-infection by hepatitis C virus (HCV) and human immunodeficiency virus (HIV) and the severity of these infections, the understanding of the biological mechanisms involved in these processes, including viral behavior and host genetic profile, is of great importance for patient treatment and for public health policies.Some single nucleotide polymorphisms (SNPs) in the human genome, such as the SNP rs1045642 (C3435T) in the MDR1 gene, have been reported to be associated to the sustained virological response (SVR) to HCV treatment in HCV-HIV co-infected patients...
October 2016: Arquivos de Gastroenterologia
Marcelo de Melo Andrade Coura, Silvana Marques Silva, Romulo Medeiros de Almeida, Miles Castedo Forrest, João Batista Sousa
Background: Anal sphincter tone is routinely assessed by digital rectal examination in patients with fecal incontinence, although its accuracy in detecting sphincter defects or separating competent from incompetent muscles has not been established. Objective: In this setting, we aimed to evaluate the accuracy of digital rectal examination in grading anal defects in order to separate small from extensive cases as depicted on 3D endoanal ultrasound, using a scoring sphincter defect and correlate anal tone to anal pressures...
October 2016: Arquivos de Gastroenterologia
José Luis Braga de Aquino, Marcelo Manzano Said, Douglas Alexandre Rizzanti Pereira, Vânia Aparecida Leandro-Merhi, Paula Casals do Nascimento, Virgínia Vieitez Reis
Background: Since Chagas disease has esophageal manifestations with different degrees of involvement, the best surgical option is controversial, especially for patients with advanced chagasic megaesophagus and recurrent symptoms after previous treatment. Objective: To assess the early and late outcomes of esophagocardioplasty in a series of patients with advanced recurrent chagasic megaesophagus. Methods: This descriptive study included 19 older patients with recurrent megaesophagus grade III/IV and positive immunofluorescence for Chagas disease...
October 2016: Arquivos de Gastroenterologia
Carlos Fernando de Magalhães Francesconi, Marta Brenner Machado, Flavio Steinwurz, Rodrigo Bremer Nones, Flávio Antonio Quilici, Wilson Roberto Catapani, Sender Jankiel Miszputen, Mauro Bafutto
Background: Primary hypolactasia is a common condition where a reduced lactase activity in the intestinal mucosa is present. The presence of abdominal symptoms due to poor absorption of lactose, which are present in some cases, is a characteristic of lactose intolerance. Objective: Evaluate the efficacy of a product containing exogenous lactase in tablet form compared to a reference product with proven effectiveness in patients with lactose intolerance. Methods: Multicentre, randomized, parallel group, single-blind, comparative non-inferiority study...
October 2016: Arquivos de Gastroenterologia
Magali Dalla Nora, Rosmari Hörner, Diego Michelon De Carli, Marta Pires da Rocha, Amanda Faria de Araujo, Renato Borges Fagundes
Background: The diagnosis of H. pylori infection can be performed by non-invasive and invasive methods.The identification through a fecal antigen test is a non-invasive, simple, and relatively inexpensive test. Objective: To determine the diagnostic performance of fecal antigen test in the identification of H. pylori infection. Methods: H. pylori antigens were identified in the stools of dyspeptic patients undergoing upper gastrointestinal endoscopy...
October 2016: Arquivos de Gastroenterologia
Júlia Silveira Vianna, Ivy Bastos Ramis, Daniela Fernandes Ramos, Andrea VON Groll, Pedro Eduardo Almeida da Silva
Background: Helicobacter pylori has a worldwide distribution and is associated with the pathogenesis of various diseases of the digestive system. Treatment to eradicate this microorganism involves the use of a combination of antimicrobials, such as amoxicillin, metronidazole, clarithromycin, and levofloxacin, combined with proton pump inhibitors. Although the current therapy is effective, a high rate of treatment failure has been observed, mainly because of the acquisition of point mutations, one of the major resistance mechanisms developed by H...
October 2016: Arquivos de Gastroenterologia
Maria do Carmo Friche Passos
No abstract text is available yet for this article.
October 2016: Arquivos de Gastroenterologia
Coskun Ozturker, Ergenekon Karagoz, Huseyin Onur Sildiroglu
No abstract text is available yet for this article.
July 2016: Arquivos de Gastroenterologia
Carlos Walter Sobrado, Raquel Franco Leal, Lucas Faraco Sobrado
The main objectives of clinical therapy in Crohn's disease are clinical and endoscopic remission without the use of corticosteroids for long periods of time, prevention of hospitalization and surgery, and improvement of quality of life. The main limitation of drug therapy is the loss of response over the long term, which makes incorporation of new drugs to the therapeutic arsenal necessary. This review analyses the main drugs currently used in clinical treatment of Crohn's disease.
July 2016: Arquivos de Gastroenterologia
Danusa Rossi, Lucas Homercher Galant, Claudio Augusto Marroni
BACKGROUND: Fatigue is a common complaint in patients with liver disease and may be considered a disabling symptom, affecting their quality of life and mental health. The Brazilian version of the Fatigue Severity Scale showed sensitivity to assess fatigue in some populations, but has not been tested in cirrhotic individuals. OBJECTIVE: The aim of this study was to evaluate the reliability of the Fatigue Severity Scale and association with depression and quality of life in patients with liver cirrhosis...
July 2016: Arquivos de Gastroenterologia
Gustavo Andrade de Paulo, Fernanda Prata Borges Martins, Erika Pereira de Macedo, Manoel Ernesto Peçanha Gonçalves, Angelo Paulo Ferrari
BACKGROUND: - Adequate bowel preparation is critical for the quality of colonoscopy. Despite reported occurrence of colonic explosion due to methane and hydrogen production by bacterial fermentation during colonoscopy, gas exchange during the procedure is believed to be effective in lowering existing methane concentration, allowing for safe utilization of mannitol for bowel preparation. Thus, mannitol is widely used for bowel cleansing prior to colonoscopy, considering its low cost and effectiveness for bowel preparation...
July 2016: Arquivos de Gastroenterologia
Ernesto Quaresma Mendonça, Lucas Snioka Zuretti, Thiago Panzani, Marianny Sulbaran, Christiano Makoto Sakai, Paulo Sakai
BACKGROUND: Endoscopic treatment of superficial gastrointestinal tumors is routinely performed, however the advantages and shortcomings of submucosal pressure-jet dissection is still debated. OBJECTIVE: - Aiming to compare this technique with conventional submucosal dissection, a study was designed in pigs. METHODS: - Areas of the antral mucosa of the stomach with a diameter of 2 cm2 (6 per animal) were marked, and resected by means of the hybrid-knife (experimental technique), and Flush-knife or IT-knife (controls)...
July 2016: Arquivos de Gastroenterologia
Maristella de Araújo Carvalho Sousa, Raymundo Paraná, Luís Jesuíno de Oliveira Andrade
BACKGROUND: - Exposure to viral antigens that share amino acid sequence similar with self- antigens might trigger autoimmune diseases in genetically predisposed individuals, and the molecular mimicry theory suggests that epitope mimicry between the virus and human proteins can activate autoimmune disease. OBJECTIVE: - The purpose of this study is to explore the possible sequence similarity between the amino acid sequences of thyroid self-protein and hepatitis C virus proteins, using databanks of proteins and immunogenic peptides, to explain autoimmune thyroid disease...
July 2016: Arquivos de Gastroenterologia
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