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Journal of Medical Economics

Ankit Shah, Margaret Duncan, Nipun Atreja, Kei Sing Tai, Mugdha Gore
OBJECTIVE: Opioid use disorder (OUD) can be managed with medication assisted therapy (MAT) (methadone [MET], buprenorphine [BUP], or extended-release naltrexone [XR-NTX]) or counseling alone (non-pharmacological therapy [NPT]). The objective of this study was to evaluate healthcare resource utilization and costs associated with XR-NTX compared with alternative treatments for opioid dependence. METHODS: Adults with a diagnosis of opioid dependence who initiated treatment with XR-NTX, BUP, MET, or NPT between January 1, 2011 and December 31, 2014 were identified in the Truven Health MarketScan Commercial administrative claims database...
January 10, 2018: Journal of Medical Economics
Peter Carney, Derek O'Boyle, Aidan Larkin, Chris McGuigan, Killian O'Rourke
AIMS: This paper evaluates the impact of multiple sclerosis (MS) in Ireland and estimates the associated direct, indirect, and intangible costs to society based on a large nationally representative sample. MATERIALS AND METHODS: A questionnaire was developed to capture the demographics, disease characteristics, healthcare use, informal care, employment, and wellbeing. Referencing international studies, standardised survey instruments were included (e.g., CSRI, MFIS-5, EQ-5D) or adapted (EDSS) for inclusion in an online survey platform...
January 10, 2018: Journal of Medical Economics
Kiyomi Suwa, Reiko Yoshikawa, Kosuke Iwasaki, Ataru Igarashi
AIMS: Short-term effects of smoking cessation (SC) on overall health care costs are unclear. We aimed to compare the short-term medical costs between patients with SC outpatient visits (SCOVs) and those without SCOVs, consisting of SCOV itself and overall medical costs. MATERIALS AND METHODS: This study is a retrospective, observational study using a Japanese employee-based health insurance claims database (January 1, 2005-December 31, 2013). We analyzed individuals who were registered as smokers based on their medical checkup details...
January 9, 2018: Journal of Medical Economics
Justin Whetten, David N van der Goes, Huy Tran, Mark Moffett, Colin Semper, Howard Yonas
AIMS: Access to Critical Cerebral Emergency Support Services (ACCESS) was developed as a low-cost solution to providing neuro-emergent consultations to rural hospitals in New Mexico that do not offer comprehensive stroke care. ACCESS is a two-way audio visual program linking remote emergency department physicians and their patients to stroke specialists. ACCESS also has an education component in which hospitals receive training from stroke specialists on the triage and treatment of patients...
January 9, 2018: Journal of Medical Economics
Eytan M Stein, Gaetano Bonifacio, Dominick Latremouille-Viau, Annie Guerin, Sherry Shi, Patrick Gagnon-Sanschagrin, Owanate Briggs, George J Joseph
OBJECTIVE: To describe the setting, duration, and costs of induction and consolidation chemotherapy for adults with newly diagnosed acute myeloid leukemia (AML), who are candidates for standard induction chemotherapy, in the United States. METHODS: Adults newly diagnosed with AML who received standard induction chemotherapy in an inpatient setting were identified from the Truven Health Analytics MarketScan (2006-2015) and SEER-Medicare (2007-2011) databases. Patients were observed from induction therapy start to the first of hematopoietic stem cell transplant, 180 days after induction discharge, health plan enrollment/data availability end, or death...
January 5, 2018: Journal of Medical Economics
Dechang Chen, Xianyao Wan, Eliza Kruger, Can Chen, Xiaomeng Yue, Liang Wang, Jiuhong Wu
AIMS: Guidelines on treating invasive candidiasis recommend initial treatment with a broad-spectrum echinocandin (e.g., micafungin); then switching to fluconazole if isolates prove sensitive (de-escalation strategy). This study aimed to evaluate the cost-effectiveness of de-escalation from micafungin versus escalation from fluconazole from a Chinese public payers perspective. MATERIALS AND METHODS: Cost-effectiveness was estimated using a decision analytic model, in which patients begin treatment with fluconazole 400 mg/day (escalation) or micafungin 100 mg/day (de-escalation)...
January 5, 2018: Journal of Medical Economics
Andrea Barnow, Laura Goldstein, Iftekhar Kalsekar, Ray Liao, Rahul Khanna
OBJECTIVE: The purpose of this study was to examine the relationship between hospital volume of prior THERMOCOOL SMARTTOUCH Catheter use and health and economic outcomes among hospitalized patients with atrial fibrillation (AF) undergoing ablation using this device. MATERIALS AND METHODS: Patients aged ≥18 years with a primary diagnosis of AF undergoing ablation treatment using the THERMOCOOL SMARTTOUCH Catheter between January 2014 and June 2016 were identified from the Premier hospital database with the first date of such procedure being defined as the index date...
January 3, 2018: Journal of Medical Economics
Claire Ep Brough, Alan Haycox
No abstract text is available yet for this article.
January 3, 2018: Journal of Medical Economics
Jill Dreyfus, Gary Delhougne, Bobbie James, Julie Gayle, Curtis Waycaster
AIMS: Describe the utilization of clostridial collagenase ointment (CCO) and medicinal honey debridement methods in real-world inpatient and outpatient hospital settings among pressure ulcer (PU) patients and compare the frequency of healthcare re-encounters between CCO- and medicinal honey-treated patients. MATERIALS AND METHODS: De-identified hospital discharge records for patients receiving CCO or medicinal honey methods of debridement and having an ICD-9 code for PU were extracted from the U...
January 3, 2018: Journal of Medical Economics
Anita Chawla, Miranda Peeples, Nanxin Li, Rachel Anhorn, Jason Ryan, James Signorovitch
AIMS: To assess the frequency of biopsies and molecular diagnostic testing (human DNA/RNA analysis), anti-cancer drug use (genomically-matched targeted therapy [GMTT], unmatched targeted therapy [UTT], endocrine therapy [ET], and chemotherapy [CT]), and medical service costs among adults with metastatic cancer. METHODS: Adults diagnosed with metastatic breast, non-small cell lung (NSCLC), colorectal, head and neck, ovarian, and uterine cancer (2010Q1-2015Q1) were identified in the OptumHealth Care Solutions claims database and followed from first metastatic diagnosis for ≥1 month and until end of data availability...
January 3, 2018: Journal of Medical Economics
Cristoforo Incorvaia, Bruna L Gritti, Erminia Ridolo
No abstract text is available yet for this article.
January 3, 2018: Journal of Medical Economics
Catherine Waweru, Anna Steenrod, Claudia Wolff, Simon Eggington, David Jay Wright, Kathleen W Wyrwich
No abstract text is available yet for this article.
January 3, 2018: Journal of Medical Economics
Sebastian Gonzalez-McQuire, Kwee Yong, Henri Leleu, Francesco S Mennini, Alain Flinois, Carlotta Gazzola, Paul Schoen, Marco Campioni, Lucy DeCosta, Leah Fink
AIMS: To assess the real-world healthcare resource utilization (HRU) and costs associated with different treatment regimens used in the management of patients with relapsed multiple myeloma in the UK, France, and Italy. METHODS: Retrospective medical chart review of characteristics, time to progression, level of response, HRU during treatment, and adverse events (AEs). Data collection started on 1 June 2015 and was completed on 15 July 2015. In the 3 months before record abstraction, eligible patients had either disease progression after receiving one of their country's most commonly prescribed regimens or had received best supportive care and died...
December 26, 2017: Journal of Medical Economics
Oleg Borisenko, Vasily Lukyanov, Isabelle Debergh, Bruno Dillemans
AIMS: This study presents the cost-effectiveness analysis of bariatric surgery in Belgium from a third-party payer perspective for a lifetime and ten-year horizon. MATERIALS AND METHODS: A decision analytic model incorporating Markov process was developed to compare the cost-effectiveness of gastric bypass, sleeve gastrectomy, and adjustable gastric banding against conventional medical management (CMM). In the model, patients could undergo surgery, experience post-surgery complications, type 2 diabetes, cardiovascular diseases, or die...
December 22, 2017: Journal of Medical Economics
Bernd Brüggenjürgen, Thomas Reinhold
BACKGROUND: While specific immunotherapy (SIT) has been proven to be cost effective for the treatment of allergic rhinitis compared to symptomatic treatment, there is a lack of European studies in which sublingual (SLIT) and subcutaneous (SCIT) immunotherapy were compared. The present analysis is focused on the cost-effectiveness of SCIT compared to SLIT and symptomatic treatment of grass pollen allergy in Austria, Spain and Switzerland. It will address specific properties of the underlying healthcare systems...
December 22, 2017: Journal of Medical Economics
Xavier Badia, Peter Trainer, N R Biermasz, J Tiemensma, Agata Carreño, Montse Roset, Anna Forsythe, Susan M Webb
AIMS: Estimate a preference-based single index for the disease specific instrument (AcroQOL) by mapping it onto the EQ-5D to assist in future economic evaluations. MATERIALS AND METHODS: A sample of 245 acromegaly patients with AcroQoL and EQ-5D scores was obtained from three previously published European studies. The sample was split into two: one sub-sample to construct the model (algorithm construction sample, n = 184) and the other one to confirm it (validation sample, n = 61)...
December 20, 2017: Journal of Medical Economics
Claire de Oliveira, Joyce Cheng, Jürgen Rehm, Paul Kurdyak
AIMS: Previous work found that, among high-cost patients, those with a majority of mental health and addiction (MHA)-related costs (>50%) incur over 30% more costs than other high-cost patients. However, this work did not examine other high-cost patients in depth or whether they had any MHA-related costs. The objective of this analysis was to examine the role of MHA-related care among other high-cost patients. METHODS: Using administrative healthcare data from Ontario, Canada, this study selected all patients in the 90th percentile of the cost distribution in 2012...
December 20, 2017: Journal of Medical Economics
(no author information available yet)
No abstract text is available yet for this article.
December 11, 2017: Journal of Medical Economics
Eric Keuffel, Peter A McCullough, Thomas M Todoran, Emmanouil S Brilakis, Swetha R Palli, Michael P Ryan, Candace Gunnarsson
OBJECTIVE: Determine the net economic impact of switching from low-osmolar contrast media (LOCM) to iso-osmolar contrast media (IOCM; iodixanol) in patients undergoing inpatient coronary or peripheral angioplasty in the United States (US). METHODS: A budget impact model (BIM) was developed from a hospital perspective. Nationally representative procedural and contrast media prevalence rates, along with MARCE (major adverse renal cardiovascular event) incidence and episode-related cost data were derived from Premier Hospital Data (October 2014 to September 2015)...
December 11, 2017: Journal of Medical Economics
Shelly Ikeme, Luca Weltert, Kevin M Lewis, Gerhard Bothma, Daniela Cianciulli, Nicole Pay, Josh Epstein, Erik Kuntze
BACKGROUND: A recent randomized controlled trial showed that patients undergoing ascending aorta surgery treated with HEMOPATCH to control bleeding had a significantly better hemostasis success rate than with dry or wet gauze compression or similar standard of care (SOC). OBJECTIVE: To compare the cost-effectiveness using two different agents for hemostasis (HEMOPATCH vs dry or wet gauze compression or similar SOC) in cardiac surgery from the European hospital perspective...
December 7, 2017: Journal of Medical Economics
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