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Veterinary Clinical Pathology

Lisa C Viesselmann, Ricardo Videla, Bente Flatland
BACKGROUND: The Heska Element POC ("EPOC") is a blood gas instrument intended for use with canine, feline, and equine whole blood; no verification for use with camelid specimens has been reported. OBJECTIVES: Using camelid specimens and commercial quality control materials (QCM), we investigatee EPOC analytical performance and establish EPOC camelid reference intervals (RIs). METHODS: Camelid blood (n = 124) was analyzed using the EPOC (pH, pCO2 , pO2 , HCO3 , base excess, SO2 , sodium, potassium, chloride, ionized calcium, TCO2 , anion gap, HCT, HGB, glucose, lactate, and creatinine); plasma was analyzed using a Roche Cobas c501 (sodium, potassium, chloride, TCO2 , anion gap, glucose, and creatinine)...
July 12, 2018: Veterinary Clinical Pathology
Taher N Elmeshreghi, Tamara L Grubb, Stephen A Greene, Claude A Ragle, Jane A Wardrop
BACKGROUND: Point-of-care analyzers can provide a rapid turnaround time for critical blood test results. Agreement between the Enterprise Point-of-Care (EPOC) and bench-top laboratory analyzers is important to determine the clinical reliability of the EPOC. OBJECTIVES: The aim of the study was (1) to evaluate the precision (repeatability) of blood gas values measured by the EPOC and (2) to determine the level of agreement between the EPOC and Nova Critical Care Express (Nova CCX) for the assessment of arterial pH, blood gases, and electrolyte variables in canine and equine blood...
July 9, 2018: Veterinary Clinical Pathology
Omar Gonzales-Viera, Kerriann Casey, M Kevin Keel
No abstract text is available yet for this article.
July 9, 2018: Veterinary Clinical Pathology
Laura Z Haysom, Tekla M Lee-Fowler, Elizabeth A Spangler
BACKGROUND: Storage and temperature significantly impact bronchoalveolar lavage fluid (BALF) analysis, and shipment of samples to diagnostic laboratories is often necessary. Alternative sample preparation methods could limit storage and temperature effects. OBJECTIVES: This study aimed to determine if airway wash samples that were fixed in formalin after being embedded in Histogel or Gelfoam gave comparable results to fresh cytocentrifuged or sediment smear preparations for the evaluation of cell morphology...
June 27, 2018: Veterinary Clinical Pathology
Susan P Boyd, Matthew P Best
A healthy 14-year-old, male neutered, Miniature Poodle was found to have a persistent erythrocyte macrocytosis and reticulocytosis with a normal and stable HCT. The hematologic features of macrocytosis, increased Howell-Jolly bodies, and metarubricytosis, in the absence of anemia or other cytopenias, combined with the cytologic evidence of bone marrow erythroid dysplasia, including megaloblastosis, binuclearity, increased mitotic activity, and nuclear fragmentation, are consistent with previous reports of congenital dyserythropoiesis termed poodle macrocytosis...
June 27, 2018: Veterinary Clinical Pathology
Mara S Varvil, Lorraine A Corriveau, Craig A Thompson
No abstract text is available yet for this article.
June 25, 2018: Veterinary Clinical Pathology
Joseph Cyrus Parambeth, Annalisa M Hernandez, Mary B Nabity, Karen E Russell, Alexandra N Myers, Melanie L Puchot, Kate E Creevy, Jonathan A Lidbury
No abstract text is available yet for this article.
June 11, 2018: Veterinary Clinical Pathology
Christof A Bertram, Kristina Dietert, Laura Pieper, Nancy A Erickson, Ann K Barton, Robert Klopfleisch
BACKGROUND: During bronchoalveolar lavage fluid (BALF) sample preparation in horses, several technical aspects can affect sample variability. To date, the effects of different fixatives on prepared equine BALF films have been insufficiently investigated. OBJECTIVES: This study aimed to determine the effect of various on-slide fixation methods on cell quality, including spray fixation of wet films, and acetone and methanol fixation of air-dried samples in comparison with unfixed, air-dried films...
June 8, 2018: Veterinary Clinical Pathology
Sarah C Roode, Heather R Shive, Willemijn Hoorntje, Jennifer Bernard, Devorah M Stowe, Roy R Pool, Carol B Grindem
A 20-month-old female spayed Staffordshire Terrier (22.3 kg) presented to the Orthopedic Surgery Service at North Carolina State University Veterinary Teaching Hospital for evaluation of a 6-week history of toe-touching to nonweight-bearing lameness in the right hind limb. Radiographs of the right stifle revealed a multiloculated lytic lesion of the distal femur, with a large open lytic zone centrally, numerous osseous septations peripherally, and focal areas of cortical thinning and loss. An aspirate of the right distal femoral lesion yielded mildly cloudy serosanguineous fluid...
May 21, 2018: Veterinary Clinical Pathology
Ashleigh W Newman, Midori G Asakawa, Tracy Stokol
No abstract text is available yet for this article.
May 14, 2018: Veterinary Clinical Pathology
Graham Stock, Nikola Pantchev, Majda Globokar
No abstract text is available yet for this article.
May 9, 2018: Veterinary Clinical Pathology
Austin K Viall, Alejandro Larios Mora, Matthew T Brewer, Joseph S Smith, Amanda J Kreuder, Ryan M Breuer, Amanda J Fales-Williams
No abstract text is available yet for this article.
May 7, 2018: Veterinary Clinical Pathology
Angela B Royal, Brian Jochems
No abstract text is available yet for this article.
May 7, 2018: Veterinary Clinical Pathology
Maggie R McCourt, Alexandra M Dieterly, Paige E Mackey, Shane D Lyon, Theresa E Rizzi, Jerry W Ritchey
An 8-year-old, intact female, mixed-breed dog presented to the Oklahoma State University Boren Veterinary Medical Teaching Hospital for evaluation of progressive lameness and joint effusion of multiple joints. Physical examination revealed joint effusion of the elbow, hock, and stifle joints bilaterally, enlarged left axillary and right popliteal lymph nodes, a subcutaneous mass over the left elbow, and a subcutaneous mass involving the left second and third mammary glands. Cytologic examination of the mammary mass, enlarged lymph nodes, and joint fluid from most affected joints revealed a monomorphic population of loosely cohesive neoplastic epithelial cells...
May 7, 2018: Veterinary Clinical Pathology
Katarzyna Paździor-Czapula, Iwona Otrocka-Domagała, Patrycja Myrdek, Mateusz Mikiewicz, Michał Gesek
Dirofilaria repens is an endemic, zoonotic parasite of carnivores, causing subcutaneous dirofilariasis, which is mostly asymptomatic. The aim of this study was to describe 22 cases of canine subcutaneous dirofilariasis. The cytologic and histopathologic samples were collected from dogs, which presented with various clinical signs such as cutaneous/subcutaneous nodules, hydropericardium, ascites, and lymphadenomegaly. The cytologic or histopathologic examination revealed purulent, pyogranulomatous, granulomatous or eosinophilic dermatitis/panniculitis, and the presence of D repens microfilariae or adults...
June 2018: Veterinary Clinical Pathology
Daniel Bergman, Anders Larsson, Helene Hansson-Hamlin, Anna Svensson, Bodil Ström Holst
BACKGROUND: Interfering antibodies in human serum and plasma are known to react with mammalian antibodies in immunoassays and cause false-positive test results. Although this phenomenon was recently shown in companion animals, knowledge regarding immunoassay interference in veterinary medicine is very limited. OBJECTIVES: The aims of this study were to set up a species-independent immunoassay procedure to detect interference in serum samples, to screen for interference in a cross-section of canine and feline patient samples from an animal hospital, and to determine if the detected interference could be neutralized using an immunoassay based on nonmammalian reagents...
June 2018: Veterinary Clinical Pathology
Wendy Sprague
No abstract text is available yet for this article.
June 2018: Veterinary Clinical Pathology
Valarie A Pallatto, Molly A Bechtold
A 9-year-old spayed female English Mastiff was referred for outpatient ultrasound due to a 3-week history of weight loss, vomiting, and decreased appetite. Abdominal ultrasound showed multiple splenic masses of varying sizes and serum chemistry panel showed hyperglobulinemia. Cytologic examination of fine-needle aspirates of the splenic masses indicated a mast cell and plasma cell collision tumor. Results of serum and urine protein electrophoresis and immunofixation indicated the plasma cell neoplasia was producing IgA immunoglobulins...
June 2018: Veterinary Clinical Pathology
Filipe Fontes Pinto, Ricardo Marcos
No abstract text is available yet for this article.
June 2018: Veterinary Clinical Pathology
Pasquale Santoro
No abstract text is available yet for this article.
June 2018: Veterinary Clinical Pathology
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