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Veterinary Clinical Pathology

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https://www.readbyqxmd.com/read/28991391/evaluation-of-reticulocyte-hemoglobin-content-ret-he-in-the-diagnosis-of-iron-deficient-erythropoiesis-in-dogs
#1
Jannika Fuchs, Andreas Moritz, Esther Grußendorf, Jörg Lechner, Felix Neuerer, Rafael Nickel, Thomas Rieker, Claudia Schwedes, Dennis B DeNicola, James Russell, Natali Bauer
BACKGROUND: Reticulocyte hemoglobin content provided by the Siemens ADVIA (CHr) is an established marker of iron deficiency. The IDEXX ProCyte Dx hematology analyzer now provides a similar variable, reticulocyte hemoglobin equivalent (RET-He). OBJECTIVES: The objective was to evaluate RET-He and its diagnostic utility in dogs, and to calculate a cutoff value for diagnosing iron-deficient erythropoiesis (IDE). Furthermore, the prevalence of RET-He values below this cutoff value was established...
October 9, 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28902964/plasmatic-coagulation-and-fibrinolysis-in-healthy-and-otostrongylus-affected-northern-elephant-seals-mirounga-angustirostris
#2
Sarrah Kaye, Shawn Johnson, Carlos Rios, Daniel J Fletcher
BACKGROUND: Prepatent Otostrongylus arteritis results in hemorrhagic diathesis in free-ranging Northern elephant seals (Mirounga angustirostris) attributed to aberrant larval migration of the lungworm, Otostrongylus circumlitus. Clinical signs are often nonspecific, including lethargy, anorexia, and blepharospasm, but can progress to spontaneous frank hemorrhage and death within 72 hours of onset. Previously published case reports describe coagulopathy with prolonged PT and APTT, normal to elevated platelet counts, normal antithrombin concentrations, and low concentrations of fibrinogen degradation products...
September 13, 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28902958/nonregenerative-immune-mediated-anemia-associated-with-a-diffuse-large-b-cell-lymphoma-in-a-captive-jaguar-panthera-onca
#3
Monika A Keresztes, Manfred Henrich, Penelope Baloi, Sascha Gerst, Jens-Christian Rudnick, Judith Langenstein, Andreas Moritz, Natali Bauer
An 18-year-old male castrated jaguar (Panthera onca) was presented with anorexia and continuous bleeding from the oral cavity after a history of fighting with the partner animal. Clinical evaluation revealed ulcerating lesions on the gingiva and hard palate and a hematoma on the tongue. Computed tomography of the head and endoscopic examination of the esophagus and stomach were unremarkable. Hematology and clinical chemistry revealed severe nonregenerative anemia, mild thrombocytopenia, and moderate azotemia...
September 13, 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28892190/parasitemia-due-to-sarcocystis-neurona-like-infection-in-a-clinically-ill-domestic-cat
#4
Nina C Zitzer, Antoinette E Marsh, Mary Jo Burkhard, M Judith Radin, Maxey L Wellman, Maria Jugan, Valerie Parker
An 8-year-old, 6-kg, male neutered Domestic Shorthair cat was presented to The Ohio State University Veterinary Medical Center (OSU-VMC) for difficulty breathing. Physical examination and thoracic radiographs indicated pneumonia, a soft-tissue mass in the left caudal lung lobe, and diffuse pleural effusion. The effusion was classified as modified transudate. Rare extracellular elongated (~5-7 μm × 1-2 μm) zoites with a central round to oval-shaped purple to deep purple vesicular nucleus with coarsely stippled chromatin and light blue cytoplasm were seen on a peripheral blood smear...
September 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28750142/feline-leukocyte-adhesion-cd18-deficiency-caused-by-a-deletion-in-the-integrin-%C3%AE-2-itgb2-gene
#5
Thomas R Bauer, Suzanne M Pratt, Christina M Palena, Karthik Raj, Urs Giger
BACKGROUND: Leukocyte adhesion deficiency (LAD) or CD18 deficiency is an autosomal recessive immunodeficiency which has been described in people, cattle, dogs, and knockout mice. OBJECTIVES: The study goals were to characterize the clinicopathologic, immunologic, and molecular genetic features of feline LAD (FLAD) in a neutered male adult Domestic Longhair cat with severe leukocytosis and recurrent infections. METHODS: Flow cytometry evaluated surface expression of CD18 on neutrophils...
September 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28422312/what-is-your-diagnosis-cutaneous-ulcerated-nodule-in-a-geriatric-dog
#6
Marta Santos, Ana Canadas, Pablo Puente-Payo, Patrícia Dias-Pereira, Ricardo Marcos
No abstract text is available yet for this article.
September 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28422307/what-is-your-diagnosis-fine-needle-aspirate-of-a-lung-nodule-and-bronchoalveolar-lavage-from-a-dog
#7
Jelena Palić, Kathrin Busch, Stefan Unterer
No abstract text is available yet for this article.
September 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28858379/hematologic-reference-intervals-for-wild-black-vultures-coragyps-atratus
#8
Jean C A Barbara, Vivian L Ferreira, Fernanda J V Guida, Fabíola E S Prioste, Eliana R Matushima, Tânia F Raso
BACKGROUND: The Black vulture (Coragyps atratus) is the most common species of vulture and is widespread in all America. The species feeds on rotting carcasses, and large groups are frequently seen in urban areas, concentrating especially on rubbish dumps. Although C atratus is a very common species in some areas, little is known about its health in the wild. OBJECTIVES: The aim of this study was to determine hematologic RIs of wild adult Black vultures. METHODS: Blood samples were obtained from 70 wild Black vultures captured in São Paulo, Brazil...
August 31, 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28858373/electrolyte-acid-base-and-hemoglobin-oxygen-affinity-alterations-following-irradiation-and-storage-of-canine-packed-red-blood-cells
#9
Saya A Press, Edward S Cooper, Jason W Stull
BACKGROUND: Irradiation of RBC before transfusion is required to prevent transfusion-associated graft-versus-host disease for human patients undergoing hematopoietic stem cell transplantation. Additional applications for irradiated blood may exist in oncologic surgery. The effect of irradiation on canine packed RBC (pRBC) is unknown. OBJECTIVES: The aim of this study was to explore and characterize the in vitro electrolyte, acid-base, and oxygen-carrying capacity changes to pRBC immediately following irradiation and during storage...
August 31, 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28841240/preanalytic-processing-of-rat-plasma-influences-thrombin-generation-and-fibrinolysis-assays
#10
Marjory B Brooks, Alyssa P Stablein, Lynn Johnson, Albert Eric Schultze
BACKGROUND: Thrombin generation assays (TGA) have potential applications as measures of hemostatic balance in animal models. However, variations in plasma processing greatly influence human TGA, and may also impact on the translational value of TGA in animal studies. OBJECTIVES: The purpose of the study was to compare the performance characteristics of Sprague-Dawley rat plasma prepared by single vs double centrifugation protocols in TGA and fibrinolysis assays...
August 25, 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28817168/infection-with-a-novel-derogenid-trematode-in-a-flap-necked-chameleon-chamaeleo-dilepis
#11
Nancy B Collicutt, Nicole I Stacy, Heather Stockdale Walden, April Childress, Jennifer Dill, Marita Anderson, James F X Wellehan
A 2-year-old female Flap-necked chameleon (Chamaeleo dilepis) was presented with a history of anorexia. On physical examination, three 11×4×2 mm, light tan-pink, raised, gelatinous, freely movable, poorly demarcated, raised nodules were identified within the oral cavity. An impression smear contained multiple, light blue to green structures exhibiting an 18×35 μm, elliptical-shaped anterior portion and a single 1×150 μm filament with a tapered end. Initial differential etiologies included trematode ova, flagellate protozoa, fungal sporangia, plant material, and sperm...
August 17, 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28815747/what-is-your-diagnosis-erythrocyte-morphology-in-a-cow
#12
Déborah Culang, Carolyn Gara-Boivin
No abstract text is available yet for this article.
August 16, 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28815678/cutaneous-iridophoroma-in-a-green-iguana-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-iguana-iguana-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2-%C3%A2
#13
Estelle Rousselet, Carlos H De Mello Souza, James F X Wellehan, Ember D Epperson, Michael J Dark, Heather L Wamsley
An 11-year-old intact male Green iguana (Iguana iguana) was referred for treatment of a probable iridophoroma based on previous cytopathology. A periocular mass was present near the right medial canthus. Computed tomography did not show any sign of metastasis. Clinicopathologic abnormalities included lymphopenia and hyperproteinemia. Cytologic and histologic evaluations of the mass were consistent with iridophoroma. Complete surgical excision of the mass was not possible without removal of the orbit due to local tissue involvement...
August 16, 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28800150/heterozygosity-for-p2y12-receptor-gene-mutation-associated-with-postoperative-hemorrhage-in-a-greater-swiss-mountain-dog
#14
Rebecca S Flores, Mary K Boudreaux, Barbara Vasquez, Poppy Bristow, Lillian R Aronson, Kari Santoro-Beer, Mary Beth Callan
A 3-year-old, female Greater Swiss Mountain dog developed a hemoperitoneum following an exploratory laparotomy and ovariohysterectomy. Platelet count, PT, APTT, and plasma von Willebrand factor antigen concentration were within RIs. A buccal mucosal bleeding time (BMBT) was prolonged. Given the probability of a hereditary thrombopathia, the dog was administered desmopressin, fresh platelet transfusions, and aminocaproic acid to control hemorrhage. Subsequently, DNA testing for the P2Y12 receptor gene mutation identified the dog as being a heterozygote (carrier)...
August 11, 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28783866/hematologic-and-plasma-chemistry-ris-for-cultured-striped-catfish-pangasius-hypophthalmus-in-recirculating-aquaculture-systems
#15
Oscar A Galagarza, David D Kuhn, Stephen A Smith, Terry C Hrubec
BACKGROUND: Striped catfish (Pangasius hypophthalmus) is a valuable aquaculture fish species produced primarily in Southeast Asia. In the United States, it is bred as an ornamental species. Striped catfish has high productivity and great demand in numerous countries around the world, yet little is known about its normal physiology. OBJECTIVES: The objective of this study was to establish hematologic and blood chemistry RIs for healthy juvenile Striped catfish. METHODS: Blood samples were collected from 70 Striped catfish raised in recirculating aquaculture systems...
August 7, 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28750148/analytic-variability-in-the-enumeration-of-neutrophil-subpopulations-in-canine-blood
#16
Saverio Paltrinieri, Elisa Talon
BACKGROUND: Conventional differential leukocyte counts do not enumerate hyposegmented neutrophils (Hypo-PMN), ie, immature neutrophils that already lost the band morphology but are not yet completely segmented. They may be early indicators of acute inflammation. OBJECTIVES: The purpose of the study was to evaluate the analytic variability of counts of segmented neutrophils (Seg-PMN), band neutrophils (Band), hyposegmented neutrophils (Hypo-PMN), non-Bands (Hypo-PMN + Seg-PMN), and Young-PMN (Bands + Hypo-PMN) assess if Hypo- or Young-PMN identify inflammation better than Bands...
July 27, 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28745834/what-is-your-diagnosis-blood-film-from-a-black-bear-ursus-americanus
#17
Angela D Gwynn, Leslie Sharkey, Rick Gerhold, Anthony Holland, Edmund J Isaac, Shelly Michalski, Laura Teigen
No abstract text is available yet for this article.
July 26, 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28745826/comparison-of-biuret-and-refractometry-methods-for-the-serum-total-proteins-measurement-in-ruminants
#18
Panagiotis D Katsoulos, Labrini V Athanasiou, Maria A Karatzia, Nektarios Giadinis, Harilaos Karatzias, Constantin Boscos, Zoe S Polizopoulou
BACKGROUND: Determination of serum total protein concentration is commonly performed by the biuret method. Refractometric measurement is a faster and less expensive alternative but its accuracy has not been determined in ruminants. OBJECTIVE: The purpose of the study was to compare the serum total protein concentrations in cattle, sheep, and goats measured by the biuret method with those obtained by refractometry. METHODS: Serum total protein concentration was determined in 120 cattle, 67 sheep, and 58 goat blood samples refractometrically and with the biuret method...
July 26, 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28741308/what-is-your-diagnosis-lymph-node-aspirates-from-a-dog-with-prominent-lymphadenomegaly
#19
Charalampos Attipa, Fiona Brooks, Alison Wilson, Ragnhild Skulberg, Kate English
No abstract text is available yet for this article.
July 24, 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28741302/estimates-of-biologic-variation-in-specific-feline-pancreatic-lipase-concentrations-in-cats-without-clinical-or-ultrasonographic-evidence-of-pancreatitis
#20
Margaret Cohn-Urbach, Craig G Ruaux, Sarah Nemanic
BACKGROUND: Serum concentrations of feline-specific pancreatic lipase are commonly used for diagnosis and monitoring of pancreatitis in cats, but little is known regarding biologic variation of this analyte. OBJECTIVES: The purpose of the study was to determine biologic variation, index of individuality, and reference change values (RCV) for specific feline pancreatic lipase concentrations (Spec fPL) in apparently healthy cats. METHODS: Four blood samples were collected prospectively from 12 apparently healthy cats at 2-week intervals...
July 24, 2017: Veterinary Clinical Pathology
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