Neimat A Yassin, Maha Abdelsalam, Amr M El-Sabbagh, Amira I Morsy, Amira A Haleem, Ibrahim El-Shenbaby, Gehan A El Wakeel, Ayman Hammad, Nashwa Hamdy, Dena M Abd-El Ghafaar, Eman B Elmarghany, Mai S Korkor, Riham Eid
Although many drugs are available for childhood systemic lupus erythematosus (SLE) treatment, the adverse effects and poor response in some cases make it crucial to find new drugs targeting various pathways in disease pathogenesis to improve overall outcomes. This study aimed to (i) investigate the effect of Panobinostat on cultured lymphocytes obtained from children with active SLE and (ii) to compare that effect with standard drugs used in SLE, such as Prednisone and hydroxychloroquine. The study included 24 SLE active patients, divided into four equal groups...
October 2023: Egyptian Journal of Immunology