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International Journal of Neuropsychopharmacology

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https://www.readbyqxmd.com/read/28340122/potential-role-of-patients-cyp3a-status-in-clozapine-pharmacokinetics
#1
Katalin Tóth, Gábor Csukly, Dávid Sirok, Ales Belic, Ádám Kiss, Edit Háfra, Máté Déri, Ádám Menus, István Bitter, Katalin Monostory
Background: The atypical antipsychotic clozapine is effective in treatment-resistant schizophrenia; however, the success or failure of clozapine therapy is substantially affected by the variables that impact the clozapine blood concentration. Thus, elucidating the inter-individual differences in clozapine pharmacokinetics can facilitate the personalized therapy. Methods: Since potential role in clozapine metabolism is assigned to CYP1A2, CYP2C19, CYP2D6 and CYP3A enzymes, the association between the patients' CYP-status (CYP genotypes, CYP expression) and clozapine clearance was evaluated in 92 psychiatric patients...
March 18, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28340169/histamine-receptors-in-the-cross-talk-between-periphery-and-brain
#2
Maria Lindskog
No abstract text is available yet for this article.
March 15, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28340244/bupropion-administration-increases-resting-state-functional-connectivity-in-dorso-medial-prefrontal-cortex
#3
Ewelina Rzepa, Zola Dean, Ciara McCabe
Background: Patients on the selective serotonergic re-uptake inhibitors (SSRI) like citalopram report emotional blunting. We have shown previously that citalopram reduces resting-state functional connectivity (RSFC) in healthy volunteers in a number of brain regions including the dorso-medial prefrontal cortex, which may be related to its clinical effects. Bupropion is a dopaminergic and noradrenergic re-uptake inhibitor (DNRI) and is not reported to cause emotional blunting. However how bupropion affects RSFC in healthy controls remains unknown...
March 11, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28339814/modulating-oxidative-stress-relieves-stress-induced-behavioral-and-cognitive-impairments-in-rats
#4
Naimesh Solanki, Ankita Salvi, Gaurav Patki, Samina Salim
Background: Persistent psychological stress often leads to anxiety disorders and depression. Benzodiazepines and selective serotonin reuptake inhibitors are popular treatment options but have limited efficacy, supporting the need for alternative treatment. Based on our recent preclinical work suggesting a causal link between neurobehavioral deficits and elevated oxidative stress, we hypothesized that interventions that mitigate oxidative stress can attenuate/overcome neurobehavioral deficits...
February 24, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28339795/erratum
#5
(no author information available yet)
No abstract text is available yet for this article.
February 24, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28339691/z-guggulsterone-produces-antidepressant-like-effects-in-mice-through-activation-of-the-bdnf-signaling-pathway
#6
Chao Huang, Wen-Feng Hu, Ji-Li Wang, Peng Wang, Yu Gong, Li-Juan Tong, Bo Jiang, Wei Zhang, Yi-Bin Qin, Zhuo Chen, Rong-Rong Yang
Background: Z-guggulsterone, an active compound extracted from the gum resin of the tree commiphora mukul, has been shown to improve animal memory deficits via activating the brain-derived neurotrophic factor (BDNF) signaling pathway. Here, we investigated the antidepressant-like effect of Z-guggulsterone in a chronic unpredictable stress (CUS) mouse model of depression. Methods: The effects of Z-guggulsterone were assessed in mice tail suspension test (TST), forced swimming test (FST)...
February 21, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28204607/aripiprazole-once-monthly-400-mg-comparison-of-pharmacokinetics-tolerability-and-safety-of-deltoid-versus-gluteal-administration
#7
Arash Raoufinia, Timothy Peters-Strickland, Anna-Greta Nylander, Ross A Baker, Anna Eramo, Na Jin, Patricia Bricmont, Jennifer Repella, Robert D McQuade, Peter Hertel, Frank Larsen
No abstract text is available yet for this article.
February 15, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28204487/cry-baby-cry-expression-of-distress-as-a-biomarker-and-modulator-in-autism-spectrum-disorder
#8
Gianluca Esposito, Noboru Hiroi, Maria Luisa Scattoni
No abstract text is available yet for this article.
February 15, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28201726/discontinuation-efficacy-and-safety-of-cholinesterase-inhibitors-for-alzheimer-s-disease-a-meta-analysis-and-meta-regression-of-44-randomized-clinical-trials-enrolling-16-245-patients
#9
Lídia Blanco-Silvente, Xavier Castells, Marc Saez, Maria Antònia Barceló, Josep Garre-Olmo, Joan Vilalta-Franch, Dolors Capellà
No abstract text is available yet for this article.
February 13, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28199677/use-of-a-spin-strategy-can-result-in-unreliable-research-findings
#10
Yasuyuki Okumura
No abstract text is available yet for this article.
February 11, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28199666/the-role-of-dopamine-d1-and-d3-receptors-in-n-methyl-d-aspartate-nmda-glycineb-site-regulated-complex-cognitive-behaviors-following-repeated-morphine-administration
#11
Yunpeng Wang, Fangyuan Yin, Hao Guo, Jing Zhang, Peng Yan, Jianghua Lai
No abstract text is available yet for this article.
February 11, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28177082/5-ht2a-agonists-a-novel-therapy-for-functional-neurological-disorders
#12
Alexander Bryson, Olivia Carter, Trevor Norman, Richard Kanaan
No abstract text is available yet for this article.
February 8, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28177081/the-working-memory-and-dorsolateral-prefrontal-hippocampal-functional-connectivity-changes-in-long-term-survival-breast-cancer-patients-treated-with-tamoxifen
#13
Xingui Chen, Xiaoxuan He, Longxiang Tao, Jingjing Li, Jiaonan Wu, Chunyan Zhu, Fengqiong Yu, Lei Zhang, Jingjie Zhang, Bensheng Qiu, Yongqiang Yu, Kai Wang
No abstract text is available yet for this article.
February 8, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28165131/structural-integrity-in-the-sustained-antidepressant-effect-of-ketamine
#14
Pauline Belujon
No abstract text is available yet for this article.
February 6, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28165117/decreased-nucleus-accumbens-expression-of-psychiatric-disorder-risk-gene-cacna1c-promotes-susceptibility-to-social-stress
#15
Chantelle E Terrillion, T Chase Francis, Adam C Puche, Mary Kay Lobo, Todd D Gould
No abstract text is available yet for this article.
February 6, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28158790/igfbp2-produces-rapid-acting-and-long-lasting-effects-in-rat-models-of-post-traumatic-stress-disorder-via-a-novel-mechanism-associated-with-structural-plasticity
#16
Jeffrey Burgdorf, Elizabeth M Colechio, Nayereh Ghoreishi-Haack, Amanda L Gross, Christopher S Rex, Xiao-Lei Zhang, Patric K Stanton, Roger A Kroes, Joseph R Moskal
No abstract text is available yet for this article.
February 1, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28158734/activation-of-extracellular-signal-regulated-kinases-erk-1-2-in-the-locus-coeruleus-contributes-to-pain-related-anxiety-in-arthritic-male-rats
#17
Gisela Borges, Cristina Miguelez, Fani Neto, Juan Antonio Micó, Luisa Ugedo, Esther Berrocoso
No abstract text is available yet for this article.
February 1, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28158336/distinct-antidepressant-like-and-cognitive-effects-of-antidepressants-with-different-mechanisms-of-action-in-middle-aged-female-mice
#18
Yan Li, Connie Sanchez, Maria Gulinello
No abstract text is available yet for this article.
February 1, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28158462/nmda-glutamate-receptor-antagonism-and-the-heritable-risk-for-alcoholism-new-insights-from-a-study-of-nitrous-oxide
#19
John H Krystal, Ismene L Petrakis, Stephanie O'Malley, Suchitra Krishnan-Sarin, Godfrey Pearlson, Gihyun Yoon
No abstract text is available yet for this article.
January 31, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28339618/telomere-length-oxidative-stress-inflammation-and-bdnf-levels-in-siblings-of-patients-with-bipolar-disorder-implications-for-accelerated-cellular-aging
#20
Mirela Paiva Vasconcelos-Moreno, Gabriel Rodrigo Fries, Carolina Gubert, Bárbara Tietböhl Martins Quadros Dos Santos, Adam Fijtman, Juliana Sartori, Pamela Ferrari, Lucas Kich Grun, Mariana Migliorini Parisi, Fátima Theresinha Costa Rodrigues Guma, Florencia Maria Barbé-Tuana, Flávio Kapczinski, Adriane Ribeiro Rosa, Lakshmi N Yatham, Marcia Kauer-Sant'Anna
Background: Growing evidence supports the existence of neurobiological trait abnormalities in individuals at genetic risk for bipolar disorder. The aim of this study was to examine potential differences in brain-derived neurotrophic factor, cytokines, oxidative stress, and telomere length markers between patients with bipolar disorder, their siblings, and healthy controls. Methods: Thirty-six patients with bipolar disorder type I, 39 siblings, and 44 healthy controls were assessed...
January 30, 2017: International Journal of Neuropsychopharmacology
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