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Biological Research for Nursing

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https://www.readbyqxmd.com/read/28413933/primer-in-genetics-and-genomics-article-3-explaining-human-diversity-the-role-of-dna
#1
Catherine Y Read
Genetic variation lays the foundation for diversity and enables humans to adapt to changing environments. The order of the nucleotides adenine, guanine, cytosine, and thymine on the deoxyribonucleic acid (DNA) molecules of the nuclear chromosomes and mitochondrial DNA (mtDNA) plays an important role in normal cell division, tissue development, and reproduction but is susceptible to alteration from a large number of random, inherited, or environmental events. Variations can range from a change in a single nucleotide to duplication of entire chromosomes...
May 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28413931/glucose-variations-and-activity-are-strongly-coupled-in-sleep-and-wake-in-young-adults-with-type-1-diabetes
#2
Sarah S Farabi, David W Carley, Lauretta Quinn
BACKGROUND: Glucose variations are common throughout sleep and wakefulness in people with type 1 diabetes mellitus (T1DM). The objective of this investigation was to characterize the time-varying coupling between glucose and unstructured physical activity over a 60-hr period in young adults with T1DM. The hypothesis was that coupling would differ during sleep versus wakefulness and would exhibit circadian variations. METHOD: Young adults with T1DM treated with an insulin pump participated in the study...
May 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28413930/relationship-of-genetic-variants-with-procedural-pain-anxiety-and-distress-in-children
#3
Anne L Ersig, Debra L Schutte, Jennifer Standley, Elizabeth Leslie, Bridget Zimmerman, Charmaine Kleiber, Kirsten Hanrahan, Jeffrey C Murray, Ann Marie McCarthy
OBJECTIVE: This study used a candidate gene approach to examine genomic variation associated with pain, anxiety, and distress in children undergoing a medical procedure. STUDY DESIGN: Children aged 4-10 years having an IV catheter insertion were recruited from three Midwestern children's hospitals. Self-report measures of pain, anxiety, and distress were obtained as well as an observed measure of distress. Samples were collected from children and biological parents for analysis of genomic variation...
May 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/27646016/a-systematic-review-of-dna-methylation-and-preterm-birth-in-african-american-women
#4
Veronica Barcelona de Mendoza, Michelle L Wright, Comfort Agaba, Laura Prescott, Alexandra Desir, Cindy A Crusto, Yan V Sun, Jacquelyn Y Taylor
BACKGROUND: The causes of many cases of preterm birth (PTB) remain enigmatic. Increased understanding of how epigenetic factors are associated with health outcomes has resulted in studies examining DNA methylation (DNAm) as a contributing factor to PTB. However, few studies on PTB and DNAm have included African American women, the group with the highest rate of PTB. METHODS: The objective of this review was to systematically analyze the existing studies on DNAm and PTB among African American women...
May 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28198200/roux-en-y-gastric-bypass
#5
V E Fernández-Ruiz, D Armero-Barranco, J M Xandri-Graupera, J A Paniagua-Urbano, M Solé-Agustí, J Mulero
BACKGROUND: Roux-en-Y gastric bypass (RYGB) is considered the gold standard for gastric bypass, displaying better results for metabolic disorders than other surgical procedures over the long term. The aim of this study was to determine the effects of bariatric surgery, in particular the RYGB technique, on metabolic syndrome (MS) and other biochemical parameters implicit in the comorbid conditions associated with obesity, as well as to explore the influence of this surgical procedure on psychiatric comorbidity in the study population...
March 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28198198/comparative-evaluation-of-pain-stress-neuropeptide-y-acth-and-cortisol-levels-between-a-conventional-postoperative-care-protocol-and-a-fast-track-recovery-program-in-patients-undergoing-major-abdominal-surgery
#6
Maria Kapritsou, Elizabeth D Papathanassoglou, Evangelos Bozas, Dimitrios P Korkolis, Evangelos A Konstantinou, Ioannis Kaklamanos, Margarita Giannakopoulou
BACKGROUND: Fast-track (FT) postoperative protocol in oncological patients after major abdominal surgery reduces complications and length of postoperative stay compared to the conventional (CON) protocol. However, stress and pain responses have not been compared between the two protocols. OBJECTIVES: To compare stress, pain, and related neuropeptidic responses (adrenocorticotropic hormone [ACTH], cortisol, and neuropeptide Y [NPY]) between FT and CON protocols. METHOD: A clinical trial with repeated measurements was conducted (May 2012 to May 2014) with a sample of 63 hepatectomized or pancreatectomized patients randomized into two groups: FT ( n = 29) or CON ( n = 34)...
March 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28198197/research-in-medical-surgical-nursing
#7
Julio Fernández-Garrido, Omar Cauli
No abstract text is available yet for this article.
March 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/27655993/effects-of-music-intervention-on-state-anxiety-and-physiological-indices-in-patients-undergoing-mechanical-ventilation-in-the-intensive-care-unit
#8
Chiu-Hsiang Lee, Chien-Ying Lee, Ming-Yi Hsu, Chiung-Ling Lai, Yi-Hui Sung, Chung-Ying Lin, Long-Yau Lin
Patients in intensive care units (ICUs) often experience stress and anxiety. Although stress and anxiety can be pharmacologically attenuated, some drugs cause adverse side effects such as bradycardia, immobility, and delirium. There is thus a need for an alternative treatment with no substantial adverse effects. Music intervention is a potential alternative. In the present study, we used cortisol levels, subjective questionnaires, and physiological parameters to explore the anxiety-reducing effects of music intervention in a sample of ICU patients on mechanical ventilation...
March 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/27306279/chlorhexidine-bathing-effects-on-health-care-associated-infections
#9
Janette Denny, Cindy L Munro
BACKGROUND: Health-care-associated infections (HAIs), infections that patients contract during the course of their hospitalization, are receiving a growing amount of attention. Heavy skin bacterial colonization aids in the transmission and development of HAIs. Nurses frequently use bathing with chlorhexidine gluconate (CHG) to reduce patients' cutaneous microbial burden. This intervention has been shown to have promising but mixed results in the prevention of HAIs. PURPOSE: This article reviews the literature for evidence on the impact of CHG bathing on HAIs...
March 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28436235/the-effect-of-epidural-analgesia-alone-and-in-association-with-other-variables-on-the-risk-of-cesarean-section
#10
Antonio Herrera-Gómez, Elvira De Luna-Bertos, Javier Ramos-Torrecillas, Francisco Manuel Ocaña-Peinado, Olga García-Martínez, Concepción Ruiz
INTRODUCTION: Epidural analgesia (EA) is the most widespread pharmacologic method of labor pain relief. There remains disagreement, however, regarding its adverse effects. The objective of this study was to determine the effect of EA administration on the risk of cesarean delivery and its causes (e.g., stalled labor, risk of loss of fetal well-being, among others) and the degree to which this effect may be modulated by mother-, newborn-, and labor-related variables. METHOD: A retrospective cohort observational study was conducted including all deliveries in a Spanish public hospital between March 2010 and March 2013 ( N = 2,450; EA = 562, non-EA = 1,888)...
January 1, 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28436234/comparison-of-hemodynamic-responses-in-the-prefrontal-cortex-according-to-differences-in-self-efficacy
#11
Kazuki Hirao
Although self-efficacy has been used extensively in the field of nursing (e.g., as an outcome measure of nursing interventions), its underlying nature is poorly understood. Investigation of the relationship between self-efficacy and brain activation will help explain the fundamental nature of self-efficacy. In this study, we compared prefrontal activation measured with near-infrared spectroscopy (NIRS) across 89 undergraduate students categorized into three groups based on their General Self-Efficacy Scale scores: low self-efficacy ( n = 59), moderate self-efficacy ( n = 17), and high self-efficacy ( n = 13)...
January 1, 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28427273/association-of-exclusive-breastfeeding-duration-with-systemic-inflammation-markers-in-adolescents-a-cross-sectional-study
#12
Emilio González-Jiménez, Jacqueline Schmidt-RioValle, Laura Sinausía, Javier S Perona
BACKGROUND: Breastfeeding duration has been associated with less low-grade inflammation in healthy adolescents, but there is scarce information regarding obese subjects. This study aimed to evaluate whether exclusive breastfeeding is related to serum concentrations of inflammatory markers in a population of Spanish adolescents. METHOD: A cross-sectional study was performed on 1,001 adolescents (13.2 ± 1.2 years) randomly recruited from schools in southeast Spain...
January 1, 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28399640/associations-of-maternal-testosterone-and-cortisol-levels-with-health-outcomes-of-mothers-and-their-very-low-birth-weight-infants
#13
June Cho, Xiaogang Su, Diane Holditch-Davis
OBJECTIVE: Although the roles of testosterone and cortisol in various health problems have been extensively investigated, little is known about their associations with health outcomes in mothers and their very-low-birth weight (VLBW) infants when maternal testosterone and cortisol are examined together during the postpartum period. METHOD: The 101 mother-VLBW infant pairs were recruited from the neonatal intensive care unit of a tertiary medical center in the southeastern United States...
January 1, 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28374630/cumulative-risk-and-physiological-stress-responses-in-african-american-adolescents
#14
Wendy Kliewer, Jo Lynne W Robins
OBJECTIVE: To investigate associations between components of cumulative risk (CR) and physiological stress responses in African American adolescents and evaluate emotion regulation as a mediator and sex as a moderator of these associations. METHODS: Cortisol and salivary alpha amylase (sAA) were collected in adolescents ( N = 205; 55% female; 12.1 ± 1.6 years at baseline) as part of a longitudinal study of stress and adjustment in families. CR was assessed at baseline and emotion regulation was assessed at baseline and 2 years later at Wave 3 (W3) using caregiver and adolescent reports...
January 1, 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28359165/testing-a-resilience-training-program-in-police-recruits
#15
Sandra L Ramey, Yelena Perkhounkova, Maria Hein, Nicole L Bohr, Amanda A Anderson
BACKGROUND: Stress from multiple sources is inherent in law enforcement. However, it is possible to modify responses to stress with resilience training that includes teaching techniques to modify emotional and physical responses to stress, interface with mental health professionals, and practice sessions to improve self-regulation of responses to stress including coherence, a measure of heart rate variability. A gap exists in the research, however, regarding evaluation of the duration of effects after the initial resilience training...
January 1, 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28347147/oxytocin-augmentation-in-spontaneously-laboring-nulliparous-women
#16
Nicole S Carlson, Elizabeth J Corwin, Nancy K Lowe
BACKGROUND: Synthetic oxytocin, the primary tool for labor augmentation, is less effective among obese women, leading to more unplanned cesarean deliveries for slow labor progress. It is not known if obese women require higher doses of oxytocin due to maternal, fetal, or labor factors related to maternal obesity. OBJECTIVES: This study had two main objectives: (1) examine the influence of maternal body mass index (BMI) on hourly doses of oxytocin from augmentation initiation until vaginal delivery in obese women; and (2) examine the influence of other maternal, fetal, and labor factors on hourly doses of oxytocin in obese women...
January 1, 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28205449/variations-in-comt-and-ntrk2-influence-symptom-burden-in-women-undergoing-breast-cancer-treatment
#17
Erin E Young, Debra Lynch Kelly, Insop Shim, Kyle M Baumbauer, Angela Starkweather, Debra E Lyon
Women with breast cancer frequently report distressing symptoms during and after treatment that can significantly erode quality of life (QOL). Symptom burden among women with breast cancer is of complex etiology and is likely influenced by disease, treatment, and environmental factors as well as individual genetic differences. The purpose of the present study was to examine the relationships between genetic polymorphisms within Neurotrophic tyrosine kinase receptor 1 (NTRK1), Neurotrophic tyrosine kinase receptor 2 (NTRK2), and catechol-O-methyltransferase ( COMT) and patient symptom burden of QOL, pain, fatigue, anxiety, depression, and sleep disturbance before, during, and after treatment for breast cancer in a subset of participants ( N = 51) in a randomized clinical trial of a novel symptom-management modality for women with breast cancer undergoing chemotherapy...
January 1, 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28196427/neurocognitive-function-is-associated-with-serum-iron-status-in-early-adolescents
#18
Xiaopeng Ji, Naixue Cui, Jianghong Liu
OBJECTIVE: The association between iron and neurocognition remains underexplored in adolescents, and the neurocognitive effects of low and high iron levels have yet to be established. The aim of this study was to investigate the relationships of low and high iron levels with neurocognitive domains in early adolescents. METHOD: The sample comprised 428 adolescents (12.0 ± 0.4 years) from Jintan, China. Serum iron concentrations were analyzed from venous blood samples and classified into low, normal, and high levels according to the clinical reference range 75-175 μg/dl...
January 1, 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28135825/il-10-gene-polymorphisms-and-self-medication-with-over-the-counter-nonsteroidal-anti-inflammatory-drugs
#19
Stephen J Walsh
BACKGROUND: Genetic influences on self-medication with over-the-counter (OTC) drugs merit investigation. For example, patients frequently use OTC nonsteroidal anti-inflammatory drugs (NSAIDs) to treat inflammation, but the inflammatory response is also affected by endogenous cytokines whose production varies across polymorphisms of their encoding genes. In the case of interleukin 10 (IL-10), literature suggests that a single nucleotide polymorphism (SNP) in the promoter region of the cytokine's gene (-1082 A > G [rs1800896]) influences production with higher levels associated with G variant alleles...
January 1, 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28135824/primer-in-genetics-and-genomics-article-2-advancing-nursing-research-with-genomic-approaches
#20
Hyunhwa Lee, Jessica Gill, Taura Barr, Sijung Yun, Hyungsuk Kim
PURPOSE: Nurses investigate reasons for variable patient symptoms and responses to treatments to inform how best to improve outcomes. Genomics has the potential to guide nursing research exploring contributions to individual variability. This article is meant to serve as an introduction to the novel methods available through genomics for addressing this critical issue and includes a review of methodological considerations for selected genomic approaches. APPROACH: This review presents essential concepts in genetics and genomics that will allow readers to identify upcoming trends in genomics nursing research and improve research practice...
January 1, 2017: Biological Research for Nursing
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