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Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs

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https://www.readbyqxmd.com/read/30426250/long-term-maintenance-of-hemoglobin-levels-in-hemodialysis-patients-treated-with-bi-weekly-epoetin-beta-pegol-switched-from-darbepoetin-alfa-a-single-center-12-month-observational-study-in-japan
#1
Toru Kawai, Yoshie Kusano, Kyouko Yamada, Chikako Ueda, Atsushi Kawai, Takao Masaki
Recent evidence on maintenance administration of epoetin beta pegol, a continuous erythropoiesis receptor activator (CERA), in dialysis patients shows the clinical benefit of bi-weekly administration (Q2W) in improving hematopoiesis and iron use efficiency. We undertook a single-center observational study of 33 Japanese maintenance dialysis patients, whose anemia had been kept stable through weekly administration (Q1W) of darbepoetin (DA), to evaluate the effectiveness of CERA Q2W switched from DA in maintaining hemoglobin (Hb) levels over a 12-month period...
November 14, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/30406438/maintaining-lower-limb-access-with-the-hero-device
#2
Marta J Madurska, David B Kingsmore, Karen S Stevenson, Peter Thomson, Ram Kasthuri
Central venous catheters (CVC) remain a mainstay of vascular access particularly for incident patients,
but lead to central vein stenosis (CVS) in up to 1 in 6 patents. This often leads to establishing dialysis access in the groin which in turn may result in development of CVS in the lower body, although this is poorly reported. The HeRO device was designed to address CVS by bypassing the stenosed veins with a nitinol-reinforced silicone tube into the right atrium, which acts as an outflow conduit attached to an arterial inflow...
November 7, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/30386926/left-ventricular-assist-device-related-infections-does-the-time-of-onset-matter
#3
Amy L Lehnert, Amanda Hart, Sara D Brouse, Richard J Charnigo, Sarah Branam, Maya E Guglin
A frequent complication of left ventricular assist devices (LVAD) is the LVAD-associated infections (LVADIs). Contamination may occur during initial surgery/admission or at a later time. We studied the clinical manifestations and outcomes of LVADIs depending on the time of the onset. Patients implanted with LVADs at our institution between August 2009 and December 2014 were included. Patients were stratified into 2 groups based on whether the infection occurred early (< 180 days) or late (≥ 180 days) after LVAD implantation...
November 2, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/30370465/mid-to-long-term-results-of-resurfacing-hip-arthroplasty-in-japanese-patients-a-comparison-of-osteoarthritic-vs-non-osteoarthritic-patients
#4
Daisuke Inoue, Tamon Kabata, Yoshitomo Kajino, Tomoharu Takagi, Takaaki Ohmori, Junya Yoshitani, Takuro Ueno, Hiroyuki Tsuchiya
Past reports showed good mid-term results of RHA for Japanese patients. However, few reports have compared the mid- to long-term results for RHA in Japanese patients with and without osteoarthritis. Therefore, this study investigated the mid- to long-term results of RHA in Japanese patients with osteoarthritis compared to those without. We conducted a retrospective review of a consecutive series of 92 hips in 80 patients (59 men and 21 women). The minimum follow-up period was 5 years. The JOA hip scoring system was used to clinically evaluate hip function...
October 28, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/30361785/effect-of-concomitant-mitral-valve-procedures-for-severe-mitral-regurgitation-during-left-ventricular-assist-device-implantation
#5
Masashi Kawabori, Chitaru Kurihara, Ryan T Conyer, Andre C Critsinelis, Tadahisa Sugiura, Todd Rosengart, Jeffrey A Morgan
The effect of performing a concomitant mitral valve procedure (MVP) during continuous-flow left ventricular assist device (CF-LVAD) implantation has been reported for patients with moderate-to-severe mitral regurgitation (MR), but moderate MR is less of a clinical concern for CF-LVAD patients. There is a paucity of reports focusing on patients with severe MR. Thus, the purpose of this study was to analyze the effect of performing a concomitant MVP during CF-LVAD implantation in patients with severe preoperative MR...
October 25, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/30349955/omental-and-deep-inferior-epigastric-artery-perforator-flap-coverage-after-heart-transplantation-to-manage-wide-left-ventricular-assist-device-exposure-with-pocket-infection
#6
Yusuke Inatomi, Hideki Kadota, Keizo Kaku, Hiromichi Sonoda, Yoshihisa Tanoue, Akira Shiose
Infection is a serious potential complication after left ventricular assist device (LVAD) implantation. In general, infection of the device pocket, with device exposure, should be managed by early device removal and heart transplantation. However, because of the small number of donors in Japan, accelerating access to heart transplantation is often difficult and the LVAD can be widely exposed during the waiting period. We report our experience of successful heart transplantation in a patient with a widely exposed LVAD with pocket infection...
October 22, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/30311022/shape-optimization-of-a-centrifugal-blood-pump-by-coupling-cfd-with-metamodel-assisted-genetic-algorithm
#7
Behnam Ghadimi, Amir Nejat, Seyed Ahmad Nourbakhsh, Nasim Naderi
A centrifugal blood pump is a common type of pump used as a left ventricular assist device in the medical industries. Therefore, the improvement of the device bio-compatibility to reduce the blood damage and to increase the efficiency has become a major challenge. In the current work, a metamodel-assisted genetic algorithm is employed to simultaneously optimize the impeller and volute geometries of a typical centrifugal blood pump. The overall shape of the base design is inspired from HeartMate3 LVAD, and the main dimensions of the base design including inlet and outlet radius, blade angle distribution, volute cross-section area distribution, etc...
October 11, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/30311021/clinical-results-and-medical-costs-of-thoracic-endovascular-aortic-repair-in-patients-over-80-years-of-age
#8
Takashi Yamauchi, Suguru Kubota, Kosei Hasegawa, Hideki Ueda
Thoracic endovascular aortic repair (TEVAR) is expected to be minimally invasive, especially in older patients. However, clinical results of TEVAR in octogenarians including medical costs are limited. Between 2010 and 2016, a total of 57 patients over 80 years of age (mean age 84.1 ± 3.4 years) underwent TEVAR at our hospital. The proximal landing zone (PLZ) was zone 0 in 7 patients (12.3%), zone 1 in 10 patients (17.5%), zone 2 in 9 patients (15.8%), zone 3 in 13 patients (22.8%), and zone 4 in 18 patients (31...
October 11, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/30298341/driveline-angle-is-crucial-for-preventing-driveline-infection-in-patients-with-heartmate-ii-device
#9
Yorihiko Matsumoto, Satsuki Fukushima, Yusuke Shimahara, Kizuku Yamashita, Naonori Kawamoto, Kensuke Kuroda, Osamu Seguchi, Masanobu Yanase, Norihide Fukushima, Hideyuki Shimizu, Junjiro Kobayashi, Tomoyuki Fujita
We hypothesized that the externalizing direction of the driveline (the driveline angle) at the percutaneous exit site would influence the occurrence of driveline infection after left ventricular assist device implantation. From August 2013 to May 2017, 71 patients were implanted with a HeartMate II device in our center. The driveline angle was measured on anteroposterior radiography just after implantation. Risk factors for driveline infection were analyzed by uni- and multivariate analyses. Driveline infection developed in 10 (14%) patients during follow-up...
October 8, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/30291469/venovenous-extracorporeal-membrane-oxygenation-for-the-management-of-critical-airway-stenosis
#10
Yu Yamada, Toshihiro Ohata, Mutsunori Kitahara, Hisakazu Kohata, Junji Kumasawa, Michihiko Kohno
Venovenous extracorporeal membrane oxygenation (VV-ECMO) is used not only support gas transfer of patients suffering from respiratory failure, but also to manage hypoxic patients with critical airway obstruction during various procedures. We present a case in which we electively used VV-ECMO to facilitate tube placement and tracheal biopsy in a 67-year-old female with critical tracheal stenosis. The patient was transferred to our hospital for a surgical treatment after emergent tracheostomy for postoperative management of cerebral hemorrhage in right putamen...
October 5, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/30284168/rolipram-plus-sivelestat-inhibits-bone-marrow-derived-leukocytic-lung-recruitment-after-cardiopulmonary-bypass-in-a-primate-model
#11
Yukinobu Goto, Yuji Hiramatsu, Naohide Ageyama, Shoko Sato, Bryan J Mathis, Shinsuke Kitazawa, Muneaki Matsubara, Hiroaki Sakamoto, Yukio Sato
Cardiopulmonary bypass (CPB) recovery is complicated by lung inflammation from bone marrow (BM)-derived polymorphonuclear leukocytes (PMNs) and monocytes (MO). Although Sivelestat reduces inflammatory mediators and Rolipram inhibits PMN and MO activation, any kinetic effects to improve CPB recovery in vivo are unknown. We hypothesized that intraoperative co-administration of these compounds would reduce CPB-induced lung inflammation through downregulation of PMN and MO recruitment. A 2-h CPB was surgically established in cynomolgus monkeys (n = 13), and BM leukocyte release and lung recruitment were monitored postoperatively by flow cytometry with 5'-bromo-2'-deoxyuridine (BrdU) and cytokine ELISA...
October 3, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/30284167/minimal-flow-ecco-2-r-in-patients-needing-crrt-does-not-facilitate-lung-protective-ventilation
#12
Onnen Moerer, Lars-Olav Harnisch, Jürgen Barwing, Daniel Heise, Jan Florian Heuer, Michael Quintel
Extracorporeal CO2 removal (ECCO2 R) is intended to facilitate lung protective ventilation in patients with hypercarbia. The combination of continuous renal replacement therapy (CRRT) and minimal-flow ECCO2 R offers a promising concept for patients in need of both. We hypothecated that this system is able to remove enough CO2 to facilitate lung protective ventilation in mechanically ventilated patients. In 11 ventilated patients with acute renal failure who received either pre- or postdilution CRRT, minimal-flow ECCO2 R was added to the circuit...
October 3, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/30251057/differences-in-activities-of-daily-living-after-hip-arthroplasty-among-hip-resurfacing-anterolateral-tha-and-posterolateral-tha-a-propensity-score-matched-analysis
#13
Takashi Sakai, Hirohito Abe, Nobuo Nakamura, Hidetoshi Hamada, Masaki Takao, Nobuhiko Sugano
The aim was to elucidate the differences in activities of daily living (ADL) after hip arthroplasty among hip resurfacing (HRA), anterolateral total hip arthroplasty (AL-THA), and posterolateral THA (PL-THA) patients after age, sex, body mass index, bilateral/unilateral hip arthroplasty, and postoperative duration were matched using propensity scores. A total of 673 hips from 540 consecutive patients who underwent hip arthroplasty were included. A self-completed questionnaire on preoperative and postoperative ADLs was administered during postsurgical visits at least ≥ 4 years postoperatively...
September 24, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/30187234/a-systematic-review-of-effectiveness-and-economic-evaluation-of-cardiohelp-and-portable-devices-for-extracorporeal-membrane-oxygenation-ecmo
#14
REVIEW
Alireza Mahboub-Ahari, Fariba Heidari, Fatemeh Sadeghi-Ghyassi, Maryam Asadi
In recent years, there have been substantial advancements in the development of different technologies for extracorporeal membrane oxygenation (ECMO) for in-hospital and out of hospital applications. However the effectiveness of these devices is not clearly known. The objective of this study was to evaluate the cost-effectiveness of Cardiohelp compared to other portable ECMO devices. In this systematic review, we searched Medline (via Ovid), Embase, Pubmed, Cochrane Library, SCOPUS, CRD and NICE. Articles were assessed by two independent reviewers for eligibility and quality of the evidence...
September 5, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/30123956/histological-investigation-of-the-titanium-fiber-mesh-with-one-side-sealed-with-non-porous-material-for-its-application-to-the-artificial-heart-system
#15
Eiji Okamoto, Kyoko Arimura, Yoshinori Mitamura
In this study, we investigated tissue-inducing characteristics of a titanium fiber mesh disk with one surface sealed with a non-porous material. We used sintered titanium fiber mesh (Hi-Lex Co., Zellez™, Hyogo, Japan) having a titanium fiber diameter of 50 µm and volumetric porosity of the titanium fiber mesh of 87% with an average pore size of 200 µm. The titanium fiber mesh is disk-shaped with a dimeter of 5 mm and a thickness of 1.5 mm. One side of the titanium fiber mesh disk was sealed with silicone rubber adhesive that has no venomousness and the sealed titanium fiber mesh disks were implanted in rats under the skin of the dorsal region, and they were extracted in the 4th and 12th postoperative weeks...
August 20, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/30039456/continuous-hemofiltration-model-using-porcine-blood-for-comparing-filter-life
#16
Yoshitaka Kurihara, Shunichi Ueki, Kenichi Kokubo, Yuta Kobayashi, Tomoyo Ebine, Kaya Murakami, Yosuke Ushiroda, Naoko Maruyama, Hiroshi Tsukao, Kozue Kobayashi, Hirosuke Kobayashi
The purpose of the present study was to establish a continuous hemofiltration model using porcine blood to compare filter life. Continuous hemofiltration (CHF) experiments were performed using an in vitro hemofilter evaluation system utilizing porcine blood containing trisodium citrate in addition to nafamostat mesilate as anticoagulants. The lifetime of the hemofilter was evaluated using the transmembrane pressure and the pressure drop across the hemofilter at varying trisodium citrate concentrations. The porcine blood used in this experiment was considered to be in a slightly hypercoagulable state because of the continuous contact with non-biological materials and calcium inflow from substitution fluid...
September 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29951930/effect-of-obesity-on-outcomes-in-patients-who-undergo-implantation-of-a-continuous-flow-left-ventricular-assist-device
#17
LETTER
Nastasya Volkovicher, Chitaru Kurihara, Andre C Critsinelis, Masashi Kawabori, Tadahisa Sugiura, Marcos A Manon, Andrew B Civitello, Jeffrey A Morgan
No abstract text is available yet for this article.
September 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29675599/immunoadsorption-plasmapheresis-treatment-for-the-recurrent-exacerbation-of-neuromyelitis-optica-spectrum-disorder-with-a-fluctuating-anti-aquaporin-4-antibody-level
#18
Hiroaki Nishimura, Hideki Enokida, Taiji Sakamoto, Toshiyuki Takahashi, Hiroshi Hayami, Masayuki Nakagawa
The pathogenesis in the exacerbation of neuromyelitis optica spectrum disorder (NMOSD) involves mainly the serum anti-aquaporin-4 (AQP4) immunoglobulin G antibody (anti-AQP4 antibody). If high-dose corticosteroid treatment is not achieved during remission, rescue plasmapheresis is recommended. However, there are few reports on the therapeutic efficacy of repetitive immunoadsorption plasmapheresis (IAPP) for the recurrent exacerbation of NMOSD with a fluctuating anti-AQP4 antibody level. A 36-year-old man presented with a reduction of visual acuity (VA) on the right eye (OD) to 20/250...
September 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29651631/sleep-and-self-care-correlates-before-and-after-implantation-of-a-left-ventricular-assist-device-lvad
#19
Jesus M Casida, Jean E Davis, Francis D Pagani, James E Aikens, Celeste Williams, James J Yang
The impact of sleep on LVAD patients' self-care behaviors is unknown. This study examined the patterns and changes of patients sleep quality (SQ), daytime sleepiness (DS), instrumental activities of daily living (IADL), and self-care capability (SCC) before and after LVAD. In addition, the relationships among these variables were explored. This observational study consisted of 38 subjects from two VAD Centers in Michigan. The subjects completed self-reported demographics and psychometrically sound SQ, DS, IADL, and SCC questionnaires before LVAD implant and at 1, 3, and 6 months after implant...
September 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29637400/design-of-in-situ-porcine-closed-circuit-system-for-assessing-blood-contacting-biomaterials
#20
Maria Chiara Munisso, Atsushi Mahara, Tetsuji Yamaoka
The overall pre-clinical process of determining the blood compatibility of any medical device involves several stages. Although the primary purpose is to protect the patients, laboratory testing has been over-utilized for many years with a huge number of unnecessary animal tests being done routinely. Recently, the elimination of needless testing has become important in controlling the cost of healthcare and in addressing many issues related to the ethics of animal research. With this in mind, we designed a new in situ porcine closed-circuit system to study the complex interplay between platelets, coagulation proteins, and other cellular elements in pigs...
September 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
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