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Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs

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https://www.readbyqxmd.com/read/30187234/a-systematic-review-of-effectiveness-and-economic-evaluation-of-cardiohelp-and-portable-devices-for-extracorporeal-membrane-oxygenation-ecmo
#1
REVIEW
Alireza Mahboub-Ahari, Fariba Heidari, Fatemeh Sadeghi-Ghyassi, Maryam Asadi
In recent years, there have been substantial advancements in the development of different technologies for extracorporeal membrane oxygenation (ECMO) for in-hospital and out of hospital applications. However the effectiveness of these devices is not clearly known. The objective of this study was to evaluate the cost-effectiveness of Cardiohelp compared to other portable ECMO devices. In this systematic review, we searched Medline (via Ovid), Embase, Pubmed, Cochrane Library, SCOPUS, CRD and NICE. Articles were assessed by two independent reviewers for eligibility and quality of the evidence...
September 5, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/30123956/histological-investigation-of-the-titanium-fiber-mesh-with-one-side-sealed-with-non-porous-material-for-its-application-to-the-artificial-heart-system
#2
Eiji Okamoto, Kyoko Arimura, Yoshinori Mitamura
In this study, we investigated tissue-inducing characteristics of a titanium fiber mesh disk with one surface sealed with a non-porous material. We used sintered titanium fiber mesh (Hi-Lex Co., Zellez™, Hyogo, Japan) having a titanium fiber diameter of 50 µm and volumetric porosity of the titanium fiber mesh of 87% with an average pore size of 200 µm. The titanium fiber mesh is disk-shaped with a dimeter of 5 mm and a thickness of 1.5 mm. One side of the titanium fiber mesh disk was sealed with silicone rubber adhesive that has no venomousness and the sealed titanium fiber mesh disks were implanted in rats under the skin of the dorsal region, and they were extracted in the 4th and 12th postoperative weeks...
August 20, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/30121790/interhospital-transport-of-ards-patients-on-extracorporeal-membrane-oxygenation
#3
Jan Florian Heuer, Moritz Mirschel, Annalen Bleckmann, Michael Quintel, Onnen Moerer
Veno-venous extracorporeal membrane oxygenation (ECMO) can be a lifesaving therapy for patients with severe acute respiratory distress syndrome (ARDS). ECMO is a technically complex and challenging procedure and should therefore only be performed in specialized centers. Transporting ARDS patients to ECMO centers for treatment can be dangerous because of the risk of hypoxemia during transport. This raises the question if ECMO should not be already initiated in the transferring hospital before transport. Over a 5-year period, we studied ARDS patients who had been transported to our department by our mobile ECMO team for further treatment after ECMO had already been initiated at the referring hospital...
August 18, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/30046934/oxygen-consumption-during-hypothermic-and-subnormothermic-machine-perfusions-of-porcine-liver-grafts-after-cardiac-death
#4
Noriyuki Morito, Hiromichi Obara, Naoto Matsuno, Shin Enosawa, Hiroyuki Furukawa
The use of grafts donated after cardiac death (DCD) would greatly contribute to the expansion of the donor organ pool. Machine perfusion (MP) is a promising technology to improve DCD liver grafts. Several perfusion technologies under various temperature and oxygenation conditions have been suggested and are still debated. It is important to confirm the relationship between oxygen consumption and organ conditions during MP. In this study, we analyzed oxygen consumption during oxygenated MP of porcine DCD liver grafts under different temperature conditions: hypothermic and subnormothermic...
July 25, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/30039457/thrombogenicity-and-long-term-cytokine-removal-capability-of-a-novel-asymmetric-triacetate-membrane-hemofilter
#5
Andreas Körtge, Thomas Wild, Benjamin Heskamp, Manuel Folk, Steffen Mitzner, Reinhold Wasserkort
Hemofilters applied in continuous renal replacement therapies (CRRTs) for the treatment of acute kidney injury must meet high standards in biocompatibility and permeability for middle and large molecules over extended treatment times. In general, cellulose-based membranes exhibit good biocompatibility and low fouling, and thus appear to be beneficial for CRRT. In this in vitro study, we compared a novel asymmetric cellulose triacetate (ATA) membrane with three synthetic membranes [polysulfone (PS), polyethersulfone (PES), and polyethylenimine-treated acrylonitrile/sodium methallyl sulfonate copolymer (AN69 ST)] regarding thrombogenicity and cytokine removal...
July 24, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/30039455/the-angle-of-the-outflow-graft-to-the-aorta-can-affect-recirculation-due-to-aortic-insufficiency-under-left-ventricular-assist-device-support
#6
Kei Iizuka, Tomohiro Nishinaka, Daichi Akiyama, Hirohito Sumikura, Toshihide Mizuno, Tomonori Tsukiya, Yoshiaki Takewa, Kenji Yamazaki, Eisuke Tatsumi
Aortic insufficiency (AI) is a crucial complication during continuous-flow left ventricular assist device (LVAD) support. Our previous clinical study suggested that a larger angle between the outflow graft and the aorta (O-A angle) could cause AI progression. This study examined the effect of the O-A angle on the hemodynamics of AI under LVAD support in an acute animal experimental model. An LVAD was installed in seven calves, with the inflow cannula inserted from the LV apex and with the outflow graft sutured at the ascending aorta...
July 23, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/30019120/correction-to-cerebral-oximetry-for-cardiac-surgery-a-preoperative-comparison-of-device-characteristics-and-pitfalls-in-interpretation
#7
Kensuke Kobayashi, Tadashi Kitamura, Satoshi Kohira, Shinzo Torii, Toshiaki Mishima, Hirotoki Ohkubo, Yuki Tanaka, Akihiro Sasahara, Takuma Fukunishi, Yuki Ohtomo, Rihito Horikoshi, Yuta Murai, Kagami Miyaji
In the original publication, the length unit of the SCD in Table 1 and Fig. 2 has been incorrectly published as cm. The correct length unit is mm.
July 17, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/30006787/the-biocompatibility-and-bioactivity-of-hemodialysis-membranes-their-impact-in-end-stage-renal-disease
#8
REVIEW
Michaela Kohlová, Célia Gomes Amorim, Alberto Araújo, Alice Santos-Silva, Petr Solich, Maria Conceição B S M Montenegro
End-stage renal disease is a growing health problem with increasing prevalence and high health care costs. Patients suffering from end-stage renal disease exhibit higher morbidity and mortality rates compared to the general population. These patients, who are treated using hemodialysis, typically suffer from anemia, inflammation, and oxidative stress. Inadequate dialyzer membrane biocompatibility exacerbates these negative side effects. Modifications of the composition of hemodialysis membranes have improved their biocompatibility and improve the patients' quality of life...
July 14, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29980955/efficient-co-2-removal-using-extracorporeal-lung-and-renal-assist-device
#9
Nozomi Takahashi, Taka-Aki Nakada, Shigeto Oda
We developed a novel system comprising acid infusion, membrane lung, and a continuous renal replacement therapy console for efficient CO2 removal at a low blood flow. To evaluate the new system, we used an ex vivo experimental model using swine blood. A liter of aliquoted blood adjusted to pH 7.25 and pCO2 65 mm Hg was mixed with acid (0, 10, or 20 mL of lactic or hydrochloric acid [1 mol/L]) and was immediately delivered to the system in a single pass. We collected blood samples at each point of the circuit and calculated the amount of CO2 eliminated by the membrane lung...
July 6, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29951931/risk-analysis-using-the-prognostic-nutritional-index-in-hemodialysis-dependent-patients-undergoing-cardiac-surgery
#10
Soki Kurumisawa, Koji Kawahito
The prognostic nutritional index is an effective prognostic tool used in gastrointestinal surgeries. However, its value has not been verified in cardiovascular surgeries. This study aimed to investigate its utility in hemodialysis-dependent patients undergoing cardiac surgery. We retrospectively reviewed data of 110 hemodialysis-dependent patients who underwent cardiac surgery between January 2006 and July 2016. 20 variables were evaluated for short- and long-term mortality prediction. Patients were divided into high and low prognostic nutritional index groups with values > 34 (n = 90) and ≤ 34 (n = 20), respectively...
June 27, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29943370/single-center-experience-of-the-bridge-to-bridge-strategy-using-the-nipro-paracorporeal-ventricular-assist-device
#11
Shuichi Yoshitake, Osamu Kinoshita, Kan Nawata, Yasuhiro Hoshino, Yoshifumi Itoda, Mitsutoshi Kimura, Haruo Yamauchi, Minoru Ono
Currently, we use the Nipro paracorporeal VAD (p-VAD) for initial short-term ventricular support, as a bridge to decision (BTD) or a bridge to candidacy (BTC) treatment, in Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) levels 1 and 2 patients. However, it is possible that compared to patients with primary implantable-VADs (P-iVAD), the bridge-to-bridge (BTB) patients are more likely to develop complications. This retrospective study used data from 24 consecutive BTB patients who were initially implanted with Nipro p-VAD as BTD or BTC treatments between April 2011 and March 2016, and subsequently underwent conversion to an i-VAD...
June 25, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29938392/efficacy-of-regional-saturation-of-oxygen-monitor-using-near-infrared-spectroscopy-for-lower-limb-ischemia-during-minimally-invasive-cardiac-surgery
#12
Teppei Toya, Tomoyuki Fujita, Satuki Fukushima, Yusuke Shimahara, Yuta Kume, Kizuku Yamashita, Yorihiko Matsumoto, Naonori Kawamoto, Junjiro Kobayashi
Lower limb ischemia with an occlusive cannula is a potential complication of minimally invasive cardiac surgery (MICS). We evaluated intraoperative local oxygen supply-demand balance by monitoring regional saturation of oxygen (rSO2 ) using near-infrared spectroscopy (NIRS), and analyzed the correlation between cannula size and fluctuation range of rSO2 . Fifty-four patients undergoing MICS surgery using femoral artery cannulation from April 2015 to August 2016 were enrolled. The rSO2 of both the cannulated and uncannulated lower limbs were measured using NIRS...
June 25, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29938391/left-ventricular-assist-device-implantation-after-plasma-exchange-for-heparin-induced-thrombocytopenia
#13
Shintaroh Koizumi, Hiroki Kohno, Michiko Watanabe, Togo Iwahana, Takuma Maeda, Shigeki Miyata, Yoshio Kobayashi, Goro Matsumiya
Treating a patient with heparin-induced thrombocytopenia can be challenging particularly when the patient requires urgent cardiac surgery that uses heparin for anticoagulation. We herein report a case of a 61-year-old man with idiopathic dilated cardiomyopathy associated with heparin-induced thrombocytopenia and who underwent plasma exchange to remove heparin-induced thrombocytopenia antibodies before undergoing left ventricular assist device implantation. The surgery was performed using cardiopulmonary bypass and unfractionated heparin...
June 25, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/30039456/continuous-hemofiltration-model-using-porcine-blood-for-comparing-filter-life
#14
Yoshitaka Kurihara, Shunichi Ueki, Kenichi Kokubo, Yuta Kobayashi, Tomoyo Ebine, Kaya Murakami, Yosuke Ushiroda, Naoko Maruyama, Hiroshi Tsukao, Kozue Kobayashi, Hirosuke Kobayashi
The purpose of the present study was to establish a continuous hemofiltration model using porcine blood to compare filter life. Continuous hemofiltration (CHF) experiments were performed using an in vitro hemofilter evaluation system utilizing porcine blood containing trisodium citrate in addition to nafamostat mesilate as anticoagulants. The lifetime of the hemofilter was evaluated using the transmembrane pressure and the pressure drop across the hemofilter at varying trisodium citrate concentrations. The porcine blood used in this experiment was considered to be in a slightly hypercoagulable state because of the continuous contact with non-biological materials and calcium inflow from substitution fluid...
September 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29951930/effect-of-obesity-on-outcomes-in-patients-who-undergo-implantation-of-a-continuous-flow-left-ventricular-assist-device
#15
LETTER
Nastasya Volkovicher, Chitaru Kurihara, Andre C Critsinelis, Masashi Kawabori, Tadahisa Sugiura, Marcos A Manon, Andrew B Civitello, Jeffrey A Morgan
No abstract text is available yet for this article.
September 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29675599/immunoadsorption-plasmapheresis-treatment-for-the-recurrent-exacerbation-of-neuromyelitis-optica-spectrum-disorder-with-a-fluctuating-anti-aquaporin-4-antibody-level
#16
Hiroaki Nishimura, Hideki Enokida, Taiji Sakamoto, Toshiyuki Takahashi, Hiroshi Hayami, Masayuki Nakagawa
The pathogenesis in the exacerbation of neuromyelitis optica spectrum disorder (NMOSD) involves mainly the serum anti-aquaporin-4 (AQP4) immunoglobulin G antibody (anti-AQP4 antibody). If high-dose corticosteroid treatment is not achieved during remission, rescue plasmapheresis is recommended. However, there are few reports on the therapeutic efficacy of repetitive immunoadsorption plasmapheresis (IAPP) for the recurrent exacerbation of NMOSD with a fluctuating anti-AQP4 antibody level. A 36-year-old man presented with a reduction of visual acuity (VA) on the right eye (OD) to 20/250...
September 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29651631/sleep-and-self-care-correlates-before-and-after-implantation-of-a-left-ventricular-assist-device-lvad
#17
Jesus M Casida, Jean E Davis, Francis D Pagani, James E Aikens, Celeste Williams, James J Yang
The impact of sleep on LVAD patients' self-care behaviors is unknown. This study examined the patterns and changes of patients sleep quality (SQ), daytime sleepiness (DS), instrumental activities of daily living (IADL), and self-care capability (SCC) before and after LVAD. In addition, the relationships among these variables were explored. This observational study consisted of 38 subjects from two VAD Centers in Michigan. The subjects completed self-reported demographics and psychometrically sound SQ, DS, IADL, and SCC questionnaires before LVAD implant and at 1, 3, and 6 months after implant...
September 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29637400/design-of-in-situ-porcine-closed-circuit-system-for-assessing-blood-contacting-biomaterials
#18
Maria Chiara Munisso, Atsushi Mahara, Tetsuji Yamaoka
The overall pre-clinical process of determining the blood compatibility of any medical device involves several stages. Although the primary purpose is to protect the patients, laboratory testing has been over-utilized for many years with a huge number of unnecessary animal tests being done routinely. Recently, the elimination of needless testing has become important in controlling the cost of healthcare and in addressing many issues related to the ethics of animal research. With this in mind, we designed a new in situ porcine closed-circuit system to study the complex interplay between platelets, coagulation proteins, and other cellular elements in pigs...
September 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29627867/effect-of-obesity-on-postoperative-outcomes-in-patients-with-left-ventricular-assist-device
#19
LETTER
Orhan Gokalp, Hasan Iner, Yuksel Besir, Nihan Karakas Yesilkaya, Gamze Gokalp, Kazim Ergunes, Sahin Iscan
No abstract text is available yet for this article.
September 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29616367/anatomical-study-of-the-cleveland-clinic-continuous-flow-total-artificial-heart-in-adult-and-pediatric-configurations
#20
Kiyotaka Fukamachi, Jamshid H Karimov, Nicole A Byram, Gengo Sunagawa, Raymond Dessoffy, Takuma Miyamoto, David J Horvath
The purpose of this study was to assess the smallest possible body sizes of patients in whom the Cleveland Clinic continuous-flow total artificial heart for adult (CFTAH) and pediatric configurations (P-CFTAH) can fit. One of the most critical dimensions is the vertebra-to-sternum distance at the junction of the right atrium to the inferior vena cava (V-S distance). Our previous CFTAH anatomical fitting study suggested that the CFTAH would fit patients of V-S distance ≥ 7.5 cm and the P-CFTAH of V-S distance ≥ 5...
September 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
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