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Surgical Infections

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https://www.readbyqxmd.com/read/28537533/risk-of-infection-and-blood-transfusion-in-trauma
#1
Charles A Karcutskie, Nicholas Namias
No abstract text is available yet for this article.
May 24, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28537494/survival-from-traumatic-injury-does-not-end-at-hospital-discharge-hospital-acquired-infections-increase-post-discharge-mortality
#2
Nitasha Dhiman, Ram C Rimal, Mark Hamill, Katie M Love, Daniel Lollar, Bryan Collier
BACKGROUND: Hospital-acquired infections (HAI) in trauma patients increase inpatient morbidity and mortality. However, their impact on long-term mortality is not well understood. PATIENTS AND METHODS: A retrospective trauma registry analysis of all patients admitted to an academic level I trauma center between July 1, 2008 and December 31, 2012 was performed. Patients included survived to discharge and were 18 years of age or older. Age, gender, Injury Severity Score (ISS), ventilator use, history of chronic obstructive pulmonary disease (COPD), and HAI were reviewed...
May 24, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28537483/mechanism-of-injury-and-risk-from-early-blood-transfusion
#3
Beuy Joob, Viroj Wiwanitkit
No abstract text is available yet for this article.
May 24, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28498097/the-asplenic-patient-post-insult-immunocompetence-infection-and-vaccination
#4
Brandon Dionne, Walter Dehority, Meghan Brett, Thomas R Howdieshell
BACKGROUND: Splenic injury can occur through multiple mechanisms and may result in various degrees of residual immunocompetence. Functionally or anatomically asplenic patients are at higher risk for infection, particularly with encapsulated bacteria. Vaccination is recommended to prevent infection with these organisms; however, the recommendations are routinely updated, and vaccine selection and timing are complex. METHODS: Review of the pertinent English-language literature, including the recommendations of the U...
May 12, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28486022/wound-concerns-and-healthcare-consumption-of-resources-after-colorectal-surgery-an-opportunity-for-innovation
#5
Puja M Shah, Heather L Evans, Amy Harrigan, Robert G Sawyer, Charles M Friel, Traci L Hedrick
BACKGROUND: Significant portions of patients undergoing colorectal surgical procedures have minor incision disturbances, yet very few meet definitions for surgical site infection (SSI). We sought to investigate the natural history of incision disturbances with a focus on the patient experience and resource utilization. We hypothesize that patients who have an incision disturbance consume frequent healthcare resources in the post-operative period despite the fact that most never receive a diagnosis of SSI...
May 9, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28475416/specific-clinical-profile-and-risk-factors-for-mortality-in-general-surgery-patients-with-infections-by-multi-drug-resistant-gram-negative-bacteria
#6
Ines Rubio-Perez, Elena Martin-Perez, Diego Domingo-García, Damian Garcia-Olmo
BACKGROUND: The incidence of gram-negative multi-drug-resistant (MDR) infections is increasing worldwide. This study sought to determine the incidence, clinical profiles, risk factors, and mortality of these infections in general surgery patients. PATIENTS AND METHODS: All general surgery patients with a clinical infection by gram-negative MDR bacteria were studied prospectively for a period of five years (2007-2011). Clinical, surgical, and microbiologic parameters were recorded, with a focus on the identification of risk factors for MDR infection and mortality...
May 5, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28472604/methodology-and-background-for-the-world-health-organization-global-guidelines-on-the-prevention-of-surgical-site-infection
#7
Angie Sway, Joseph S Solomkin, Didier Pittet, Claire Kilpatrick, Benedetta Allegranzi
Surgical site infections remain an important topic of concern for surgeons in all specialties and are currently the focus of global health agencies for prevention. Because patients have numerous co-morbidities that increase the risks of surgical site infections, and because of the emergence of more resistant pathogens, it is necessary to revise and update guidelines to assist surgeons in the prevention of these infections. This article will summarize the most recent WHO Global Guidelines for the prevention of Surgical Site Infection that will have applicability for surgeons in all countries...
May 4, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28472599/peri-prosthetic-knee-infection-management-spacers-loaded-with-two-or-three-antibiotic-agents
#8
David Joaquin Ortola, Domenico Fenga, Sandra Marcellino, Massimiliano Rosi, Francesco Centofanti, Michele Attilio Rosa
BACKGROUND: The purpose of this work was to compare pre-made antibiotic-loaded spacers with two commercially available antibiotic agents and custom-made cements with three antibiotic agents added. We evaluated: (a) the validity of our procedures, (b) the control of the rate of infection in the long term, (c) complications, and (d) quality of life and patient satisfaction. METHODS: A retrospective cohort study was performed on 112 consecutively treated patients between January 2010 and December 2013; 56 patients were treated with a pre-formed cement spacer (clindamycin + gentamicin), and 56 patients were treated with a spacer loaded with three antibiotic agents (clindamycin + gentamicin + vancomycin)...
May 4, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28467274/face-to-face-with-multi-resistant-pathogens-an-urgent-call-to-action-for-modern-surgeons-to-pioneer-in-antibiotic-stewardship
#9
Matthias May, Robert Obermaier, Alexander Novotny, Florian M Wagenlehner, Sabine D Brookman-May
No abstract text is available yet for this article.
May 3, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28414569/elevated-levels-of-plasma-mitochondrial-dna-are-associated-with-clinical-outcome-in-intra-abdominal-infections-caused-by-severe-trauma
#10
Qiongyuan Hu, Jianan Ren, Jie Wu, Guanwei Li, Xiuwen Wu, Song Liu, Gefei Wang, Guosheng Gu, Jieshou Li
BACKGROUND: The purpose of our study was to determine prospectively relationships between plasma mitochondrial deoxyribonucleic acid (mtDNA) concentration and clinical outcome in patients with intra-abdominal infections (IAIs) induced by severe abdominal trauma. PATIENTS AND METHODS: The DNA was isolated from serum samples taken from patients with IAIs at hospital days zero, one, and two. Plasma mtDNA concentration was assessed by real-time polymerase chain reaction (PCR)...
April 17, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28375806/microbiomic-analysis-of-intra-abdominal-infections-by-using-denaturing-high-performance-liquid-chromatography-a-prospective-observational-study
#11
Christian Koch, Anca L Amati, Andreas Hecker, Marcel Höxter, Marcus Hirschburger, Reginald Matejec, Winfried Padberg, Marcus A Weigand, Christoph Lichtenstern, Eugen Domann
BACKGROUND: Intra-abdominal infections represent a subgroup of septic syndromes with high death rates and the need for prompt and appropriate antimicrobial therapy. Conventional culture-based microbial identification has notable shortcomings in the diagnostics of polymicrobial infections. Modern culture-independent molecular methods may represent a new diagnostic approach. The current study aimed to compare the results obtained from the denaturing high-performance liquid chromatography WAVE(®) system as a culture-independent diagnostic tool with those obtained from standard culture-based microbiologic testing in the clinical setting of severe intra-abdominal sepsis...
April 4, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28375804/commentary-on-effect-of-the-endoclear-%C3%A2-device-on-biofilm-in-endotracheal-tubes
#12
Brad Vazales
No abstract text is available yet for this article.
April 4, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28375803/routine-use-of-prophylactic-antibiotics-during-laparoscopic-cholecystectomy-does-not-reduce-the-risk-of-surgical-site-infections
#13
Pinar Sarkut, Sadik Kilicturgay, Hikmet Aktas, Yilmaz Ozen, Ekrem Kaya
BACKGROUND: Laparoscopic cholecystectomy (LC) is the gold standard for the treatment of symptomatic gallbladder stones. As infections are rare in uncomplicated LC, it is widely accepted that prophylactic antibiotics need not be administered, and guidelines do not support routine antibiotic prophylaxis during elective LC. However, routine antibiotic prophylaxis for elective LC is still popular in many clinical settings. We investigated this situation in our department. METHOD: This randomized double-blind controlled study included 570 patients who underwent LC between March 2007 and February 2010...
April 4, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28353418/factors-associated-with-the-development-of-tertiary-peritonitis-in-critically-ill-patients
#14
Josep Ballus, Juan C Lopez-Delgado, Joan Sabater-Riera, Xose L Perez-Fernandez, Antoni J Betbese, Joan A Roncal
BACKGROUND: Critically ill surgical patients remain at a high risk of adverse outcomes as a result of secondary peritonitis (SP). The risk is even higher if tertiary peritonitis (TP) develops. Factors related to the development of TP, however, are scarce in the literature. The main aim of our study was to identify factors associated with the development of TP in patients with SP in the intensive care unit (ICU), and also to report differences in microbiologic patterns and antibiotic therapy in patients with the two conditions...
March 29, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28353417/do-patients-with-pre-existing-psychiatric-illness-have-an-increased-risk-of-infection-after-injury
#15
Catherine M Dickinson, Daniel R Karlin, Hector R Nunez, Shiliang A Cao, Daithi S Heffernan, Sean F Monaghan, Tareq Kheirbek, Charles A Adams, Andrew H Stephen
BACKGROUND: Trauma remains a leading cause of death and long term-morbidity. We have shown that patients who sustain traumatic injuries are at increased risk for the development of infectious complications. Psychiatric illnesses (PIs) are also noted to occur frequently among the general population. The presence of a PI has been shown to be a risk factor for the development of infections. Despite the prevalence of both traumatic injuries and psychiatric diseases, there are little data relating the impact of PI on the outcome of patients with trauma...
March 29, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28339315/identification-of-asymptomatic-prosthetic-joint-infection-microbiologic-and-operative-treatment-outcomes
#16
Przemysław L Bereza, Alicja Ekiel, Aleksandra Auguściak-Duma, Małgorzata Aptekorz, Iwona Wilk, Piotr Wojciechowski, Damian J Kusz, Gayane Martirosian
BACKGROUND: This prospective study investigated the role of mechanical and biological factors in aseptic implant loosening or presumed silent prosthetic joint infection (PJI). METHODS: Thirty-seven patients were investigated. Microbiologic and molecular methods were used to detect bacteria on the surface of the failed implants removed during revision arthroplasty. Histopathologic analysis was performed. The influence of body mass index (BMI) and various co-morbidities on implant failure also was determined...
March 24, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28266902/soluble-triggering-receptor-expressed-on-myeloid-cells-1-as-a-novel-marker-for-abdominal-sepsis
#17
Xiaofei Song, Yucheng Song, Xuedong Zhang, Huanzhou Xue
BACKGROUND: The aim of the study was to investigate the concentration and diagnostic significance of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) in acute abdominal conditions. METHODS: Plasma specimens were obtained from 68 patients with abdominal sepsis, 60 patients with systemic inflammatory response syndrome (SIRS), and 60 healthy individuals. The sepsis group was divided into the survival and death groups according to the 28-d outcome...
March 7, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28266900/right-colectomy-and-abdominal-perineal-resection-for-cancer-do-urinary-tract-infections-impact-outcomes
#18
John G Armstrong, Chien-Hsun Li, Junlin Liao, John C Byrn
BACKGROUND: We aim to assess the patient factors and concomitant infectious outcomes associated with urinary tract infection (UTI) occurrence and the impact of UTI on length of stay (LOS), re-admission, and death in a colorectal surgical population. PATIENTS AND METHODS: National Surgical Quality Improvement Program User Data for right colectomy and abdominal perineal resection (APR) procedures for cancer between 2006 and 2012 were analyzed. Concomitant infectious complications and timing of UTI diagnosis, inpatient versus outpatient, were considered...
March 7, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28541808/executive-summary-of-the-american-college-of-surgeons-surgical-infection-society-surgical-site-infection-guidelines-2016-update
#19
Kristen A Ban, Joseph P Minei, Christine Laronga, Brian G Harbrecht, Eric H Jensen, Donald E Fry, Kamal M F Itani, E Patchen Dellinger, Clifford Y Ko, Therese M Duane
Guidelines regarding the prevention, detection, and management of surgical site infections (SSIs) have been published previously by a variety of organizations. The American College of Surgeons (ACS)/Surgical Infection Society (SIS) Surgical Site Infection (SSI) Guidelines 2016 Update is intended to update these guidelines based on the current literature and to provide a concise summary of relevant topics.
May 2017: Surgical Infections
https://www.readbyqxmd.com/read/28541807/surgical-site-infection-research-opportunities
#20
Kamal M F Itani, E Patchen Dellinger, John Mazuski, Joseph Solomkin, George Allen, Joan C Blanchard, Rachel Kelz, Sandra I Berríos-Torres
Much has been done to identify measures and modify risk factors to decrease the rate of surgical site infection (SSI). Development of the Centers for Disease Control and Prevention (CDC) Core recommendations for the prevention of SSI revealed evidence gaps in six areas: Parenteral antimicrobial prophylaxis, glycemic control, normothermia, oxygenation, antiseptic prophylaxis, and non-parenteral antimicrobial prophylaxis. Using a modified Delphi process, seven SSI content experts identified nutritional status, smoking, obesity, surgical technique, and anemia as additional areas for SSI prevention research...
May 2017: Surgical Infections
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