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Surgical Infections

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https://www.readbyqxmd.com/read/30004836/serum-amyloid-a-as-an-early-marker-of-infectious-complications-after-laparoscopic-surgery-for-colorectal-cancer
#1
Mateusz Wierdak, Magdalena Pisarska, Beata Kuśnierz-Cabala, Jan Witowski, Piotr Major, Piotr Ceranowicz, Andrzej Budzyński, Michał Pędziwiatr
BACKGROUND: Our aim was to evaluate the usefulness of serum amyloid A (SAA) measurements in comparison with C-reactive protein (CRP) in the early prediction of infectious complications among patients undergoing laparoscopic surgery for colorectal cancer Methods: Consecutive patients undergoing laparoscopic resection for colorectal cancer were analyzed prospectively. All subjects had the Enhanced Recovery After Surgery protocol implemented. Blood samples were taken from all patients and SAA and CRP were measured on the day of surgery and on the three consecutive post-operative days (PODs)...
July 13, 2018: Surgical Infections
https://www.readbyqxmd.com/read/29979638/high-prevalence-of-vim-kpc-and-ndm-expression-among-surgical-site-infection-pathogens-in-patients-having-emergency-surgery
#2
Amani A El-Kholy, Mervat G Elanany, May M Sherif, Maha A Gad
BACKGROUND: The rate of surgical site infection (SSI) in patients who undergo emergency operations is higher than in other patients. Previous studies showed an increasing role of gram- negative pathogens (GNP) in SSI. We aimed to identify GNP causing SSIs after emergency surgery, to characterize the carbapenemase-resistance genes in carbapenem-resistant pathogens (CRPs), and to identify the risk factors for SSI caused by CRP. METHOD: We conducted a one-year prospective study from September 2014 in the Emergency Hospital of Cairo University Hospitals...
July 6, 2018: Surgical Infections
https://www.readbyqxmd.com/read/29920159/diagnosis-of-periprosthetic-joint-infection-using-polymerase-chain-reaction-an-updated-systematic-review-and-meta-analysis
#3
Yang Jun, Liu Jianghua
BACKGROUND: We aim to update a meta-analysis to evaluate the efficiency of polymerase chain reaction (PCR) for diagnosis of periprosthetic joint infection (PJI) because different types of PCR assays have yielded variable diagnostic efficiency from 2013. METHODS: We conducted our systematic review by searching for keywords in online databases from 2013 to May 2017. Studies were chosen based on inclusion and exclusion criteria and the quality of included studies was assessed...
June 19, 2018: Surgical Infections
https://www.readbyqxmd.com/read/29893614/bowel-perforation-resulting-in-necrotizing-soft-tissue-infection-of-the-abdomen-flank-and-lower-extremities
#4
Disha Kumar, Nicolás W Cortés-Penfield, Hanine El-Haddad, Daniel M Musher
BACKGROUND: Fournier's gangrene is a necrotizing soft-tissue infection (NSTI) that often originates from a break in bowel integrity and affects the perineum, anus, or genitalia. Although the pathogenesis is similar, NSTI caused by a break in bowel integrity less commonly presents as infection of other sites. OBJECTIVE: To characterize NSTIs originating from bowel perforation and presenting as infection of the abdominal wall, flank, or thigh but that largely spare the perineum, anus, and genitalia...
June 12, 2018: Surgical Infections
https://www.readbyqxmd.com/read/29883278/recent-anti-microbial-exposure-is-associated-with-more-complications-after-elective-surgery
#5
Christopher A Guidry, Puja S Shaw, Zachary C Dietch, Nathan R Elwood, Elizabeth D Krebs, J Hunter Mehaffey, Robert G Sawyer
BACKGROUND: Recent anti-microbial exposure has been associated with poor outcomes after infection in a mixed population. We hypothesized that recent anti-microbial exposure would be associated with poor outcomes of elective surgery. METHODS: From August 2015 to August 2016, all elective surgical patients were questioned prospectively about anti-microbial exposure during the prior three months. Multivariable models were used to calculate risk-adjusted odds ratios for anti-microbial exposure controlling for surgeon influence...
June 8, 2018: Surgical Infections
https://www.readbyqxmd.com/read/29874152/efficacy-of-pre-operative-antimicrobial-prophylaxis-in-patients-undergoing-pancreatoduodenectomy-a-multi-center-retrospective-analysis
#6
Judith E K R Hentzen, Marloes A Smit, Marjan J Bruins, Coen G B M Rupert, Jennifer Schreinemakers, Gijs J H M Ruijs, Gijs A Patijn
BACKGROUND: The most common complications after pancreaticoduodenectomy (PD) are infectious, despite the standard use of cefazolin and metronidazole prophylaxis. Pre-operative biliary drainage (PBD) is a well-known risk factor for infectious complications. The objective was to identify the pathogens in intra-operative bile cultures in patients undergoing PD-with and without PBD-to determine the optimal antimicrobial prophylaxis regimen. PATIENTS AND METHODS: Patients who underwent PD between 2009 and 2016 were identified retrospectively in three major teaching hospitals in The Netherlands...
June 6, 2018: Surgical Infections
https://www.readbyqxmd.com/read/29870307/high-rate-of-major-morbidity-after-surgical-excision-for-pilonidal-disease
#7
Joseph J López, Jennifer N Cooper, Devin R Halleran, Katherine J Deans, Peter C Minneci
BACKGROUND: Recurrent pilonidal disease has been reported to occur in up to 30% of patients after their initial infection. Surgical resection is often performed to prevent recurrence of disease, however, morbidity after surgical excision from incision complications and disease recurrence is common. The aim of this study was to quantify major morbidity after initial pilonidal excision. PATIENTS AND METHODS: Patients with pilonidal disease who had initial excision procedures between 2011-2013 at hospitals reporting data to the Pediatric Health Information System (PHIS) were included...
June 5, 2018: Surgical Infections
https://www.readbyqxmd.com/read/29812994/consequences-of-implementing-a-better-blood-culture-system
#8
Sarah E Posillico, Joseph F Golob, Brenda M Zosa, Nitin Sajankila, Laura A Kreiner, Jeffrey A Claridge
BACKGROUND: Blood cultures (BCx) are the gold standard for diagnosing blood stream infections. However, contamination remains a challenge and can increase cost, hospital days, and unnecessary antibiotic use. National goals are to keep overall BCx contamination rates to ≤3%. Our healthcare system recently moved to a BCx system with better organism recovery, especially for gram-negative, fastidious, and anaerobic bacteria. The study objectives were to determine the benefits/consequences of implementing a more sensitive blood culture system, specifically on contamination rates...
May 29, 2018: Surgical Infections
https://www.readbyqxmd.com/read/29750599/peri-operative-nasal-eradication-therapy-prevents-staphylococcus-aureus-surgical-site-infections-in-aortoiliac-surgery
#9
Jasper C M Langenberg, Jan A J W Kluytmans, Paul G H Mulder, Jannie Romme, Gwan H Ho, Lyckle Van Der Laan
BACKGROUND: Surgical site infections (SSIs) cause considerable morbidity and deaths among patients undergoing vascular surgery. Pre-operative screening and subsequent treatment of nasal Staphylococcus aureus carriers with mupirocin and chlorhexidine reduces the risk of SSIs in cardiothoracic and orthopedic surgery. The aim of this study was to investigate the effect of this screen-and-treat strategy on the development of SSI in patients undergoing aortoiliac surgery. METHODS: A prospective study was performed that enrolled an intervention cohort comprising all patients undergoing aortoiliac surgery from February 2013 to December 2016...
May 11, 2018: Surgical Infections
https://www.readbyqxmd.com/read/29727259/sepsis-screening-tools-in-the-era-of-sepsis-3-0
#10
Xianshi Zhou, Ye Ye, Guanghua Tang
No abstract text is available yet for this article.
May 4, 2018: Surgical Infections
https://www.readbyqxmd.com/read/29717917/higher-versus-lower-dose-of-cefotetan-or-cefoxitin-for-surgical-prophylaxis-in-patients-weighing-one-hundred-twenty-kilograms-or-more
#11
Mary Banoub, Melanie S Curless, Janessa M Smith, Andrew S Jarrell, Sara E Cosgrove, Clare Rock, Edina Avdic
BACKGROUND: Clinical practice guidelines recommend a 2-g dose of cefotetan and cefoxitin for surgical prophylaxis. Pharmacokinetic data suggest benefit from higher cefotetan and cefoxitin dosing in obese patients. However, clinical studies examining higher dosing strategies in this at-risk population are lacking. The purpose of this study was to determine whether 3 g of cefotetan or cefoxitin administered pre-operatively for patients who weigh 120 kg or more is associated with a lower proportion of surgical site infection (SSI) compared with 2 g...
May 2, 2018: Surgical Infections
https://www.readbyqxmd.com/read/29717911/epidemiology-of-trauma-related-infections-among-a-combat-casualty-cohort-after-initial-hospitalization-the-trauma-infectious-disease-outcomes-study
#12
David R Tribble, Margot R Krauss, Clinton K Murray, Tyler E Warkentien, Bradley A Lloyd, Anuradha Ganesan, Lauren Greenberg, Jiahong Xu, Ping Li, M Leigh Carson, William Bradley, Amy C Weintrob
BACKGROUND: The Trauma Infectious Disease Outcomes Study (TIDOS) cohort follows military personnel with deployment-related injuries in order to evaluate short- and long-term infectious complications. High rates of infectious complications have been observed in more than 30% of injured patients during initial hospitalization. We present data on infectious complications related to combat trauma after the initial period of hospitalization. PATIENTS AND METHODS: Data related to patient care for military personnel injured during combat operations between June 2009 and May 2012 were collected...
May 2, 2018: Surgical Infections
https://www.readbyqxmd.com/read/29708848/clostridium-difficile-infection-in-trauma-surgery-and-medical-patients-admitted-to-the-intensive-care-unit
#13
Richard R Watkins, Caroline Mangira, Farid Muakkassa, Curtis J Donskey, Nairmeen A Haller
BACKGROUND: Clostridium difficile infection (CDI) causes significant morbidity and mortality rates, especially for patients in the intensive care unit (ICU). Data comparing trauma and surgery patients with CDI in the ICU with medical patients with CDI in the ICU are limited. METHODS: In a single-center study, we analyzed retrospective data from 25 trauma patients and 13 surgery patients aged 18 years or older who had CDI and had been admitted to the ICU. A comparison group of 156 medical patients aged 18 years or greater who had CDI and were admitted to the ICU also was identified...
April 30, 2018: Surgical Infections
https://www.readbyqxmd.com/read/29683405/longitudinal-evaluation-of-plasma-concentrations-of-presepsin-in-patients-after-severe-trauma-a-prospective-observational-study
#14
Christian Koch, Sophie Ruhrmann, Michael Pöhlmann, Emmanuel Schneck, Borros Arneth, Thomas Zajonz, Michael Sander, Markus A Weigand, Florian Uhle
BACKGROUND: The high mortality rate of patients suffering from severe trauma is based not only on the mechanism of injury, but also on the higher risk for development of subsequent infections. Therefore, the early recognition of infection after severe trauma is of particular importance for patient outcome. However, early diagnosis is often masked by the consequences of the sterile, damage-triggered immune response. Our study sought to analyze the course of soluble CD14-subtype (sCD14-ST, presepsin) compared with clinically established inflammatory and infectious biomarkers in a cohort of patients with severe trauma...
April 23, 2018: Surgical Infections
https://www.readbyqxmd.com/read/29957139/a-case-of-severe-lumbar-necrotizing-soft-tissue-infection-from-an-ileal-pouch-fistula
#15
Theodore Delmonico, Andrew H Stephen, Daithi S Heffernan
BACKGROUND: Necrotizing soft tissue infection (NSTI) is a rapidly progressive infection characterized by tissue necrosis, septic shock, and is associated with a high risk of death. Key aspects of successful treatment include early recognition and emergent surgical source control. Necrotizing soft tissue infection may occur from a range of etiologies but may also occur rarely from gastrointestinal routes. We report a case of severe lumbar NSTI arising from an ileal pouch fistula in a patient with inflammatory bowel disease...
July 2018: Surgical Infections
https://www.readbyqxmd.com/read/29957138/early-onset-prosthetic-valve-endocarditis-experience-at-a-cardiothoracic-surgical-hospital-2006-2016
#16
Rafael Quaresma Garrido, José Oscar Dos Reis Brito, Ralph Fernandes, Giovanna Ferraiuoli Barbosa, Marcelo Goulart Correia, Wilma Felix Golebiovski, Clara Weksler, Cristiane C Lamas
BACKGROUND: Early onset prosthetic valve endocarditis (EO-PVE) is an serious complication associated with heart valve replacement surgery. OBJECTIVES: To describe the epidemiologic, clinical, and laboratory profile of patients with EO-PVE in a cardiac surgical hospital. PATIENTS AND METHODS: A retrospective analysis of an endocarditis database, implemented prospectively, with a post hoc study driven by analysis of cases of adults with definite endocarditis occurring up to 12 months after heart valve surgery...
July 2018: Surgical Infections
https://www.readbyqxmd.com/read/29893620/femoral-osteomyelitis-caused-by-cladophialophora-in-a-patient-without-known-immunocompromise
#17
Nirbhay S Jain, Christopher B Horn, Adrian A Coleoglou Centeno, Obeid N Ilahi, John E Mazuski, Grant V Bocchichio, Laurie J Punch
BACKGROUND: Chronic osteomyelitis associated with a stage IV decubitus ulcer is a challenging condition to manage, characterized by frequent relapses and need for long-term anti-microbial therapy. Although gram-positive cocci are the most common causes, fungal infections have been reported, usually in immunocompromised hosts. We present a case of Cladophialophora osteomyelitis in a patient without known immunocompromised that was managed with a Girdlestone pseudoarthroplasty. CASE REPORT: A 70-year-old male presented to our emergency room with fever, right hip pain, and purulent drainage from a right greater trochanter stage IV decubitus ulcer...
July 2018: Surgical Infections
https://www.readbyqxmd.com/read/29847211/effective-disinfection-of-a-burn-unit-after-two-cases-of-sepsis-caused-by-multi-drug-resistant-acinetobacter-baumannii
#18
Luís Cobrado, Ana Pinto Silva, Cidália Pina-Vaz, Acácio Rodrigues
BACKGROUND: The healthcare environment is a potential source of microbial pathogens, which may promote infectious cross-transmission. Terminal automated cleaning methods such as hydrogen peroxide systems have proven to be more successful than manual techniques. The aim of this study was to evaluate the effectiveness of an automated aerosolized hydrogen peroxide/silver cations dry-mist system. The goal was to prevent microbial transmission to patients in a clinical setting after two cases of sepsis caused by multi-drug resistant Acinetobacter baumannii had been diagnosed in a burn unit that relied on manual cleaning techniques...
July 2018: Surgical Infections
https://www.readbyqxmd.com/read/29791301/the-significance-of-interleukin-6-in-the-early-detection-of-surgical-site-infections-after-definitive-operation-for-gastrointestinal-fistulae
#19
Dongming Zhang, Jianan Ren, Mohamed-Omar Arafeh, Robert G Sawyer, Qiongyuan Hu, Xiuwen Wu, Gefei Wang, Guosheng Gu, Jiang Hu, Mingzhang Li
BACKGROUND: Surgical site infections (SSIs) are among the most common complications after definitive treatment for intestinal fistulae. Serum inflammatory markers including white blood cell count (WBC), C-reactive protein (CRP), interleukin-6 (IL-6), as well as procalcitonin (PCT) have been used to help diagnosis post-operative complications. OBJECTIVE: The goal of this study was to assess the clinical value of inflammatory markers, specifically IL-6, in predicting SSIs after intestinal fistulae resection...
July 2018: Surgical Infections
https://www.readbyqxmd.com/read/29791270/potential-for-spread-of-hand-infection-after-elastic-exsanguination
#20
Scott Farner, Laxminarayan Bhandari, David Tate
No abstract text is available yet for this article.
July 2018: Surgical Infections
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