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Surgical Infections

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https://www.readbyqxmd.com/read/28339315/identification-of-asymptomatic-prosthetic-joint-infection-microbiologic-and-operative-treatment-outcomes
#1
Przemysław L Bereza, Alicja Ekiel, Aleksandra Auguściak-Duma, Małgorzata Aptekorz, Iwona Wilk, Piotr Wojciechowski, Damian J Kusz, Gayane Martirosian
BACKGROUND: This prospective study investigated the role of mechanical and biological factors in aseptic implant loosening or presumed silent prosthetic joint infection (PJI). METHODS: Thirty-seven patients were investigated. Microbiologic and molecular methods were used to detect bacteria on the surface of the failed implants removed during revision arthroplasty. Histopathologic analysis was performed. The influence of body mass index (BMI) and various co-morbidities on implant failure also was determined...
March 24, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28332921/leaving-the-skin-incision-open-may-not-be-as-beneficial-as-we-have-been-taught
#2
Jack C He, Brenda M Zosa, David Schechtman, Brian Brajcich, Jonathan C Savakus, Amanda L Wojahn, Derek Z Wang, Jeffrey A Claridge
BACKGROUND: Currently, various methods of skin closures are used in contaminated and dirty abdominal wounds without solid, evidence-based guidance. This study investigates whether closure methods affect surgical site infection (SSI) and other incisional complications. We hypothesize that open management of the skin would have the lowest complications, including SSI. PATIENTS AND METHODS: Patients age ≥18 who underwent trauma laparotomy (TL) or damage control laparotomy (DCL) from 2008-2013 and had class III/IV wounds were included...
March 23, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28267427/prevention-of-biomaterial-infection-by-pre-operative-incubation-with-human-cells
#3
Ramón Pérez-Tanoira, Antti A Aarnisalo, Kari K Eklund, Xia Han, Antti Soininen, Veli-Matti Tiainen, Jaime Esteban, Teemu J Kinnari
BACKGROUND: Cells of tissues and biofilm forming bacteria compete for the living space on the surface of an implant. We hypothesized the incubation of the implant (titanium, polydimethylsiloxane, and polystyrene surface) with human cells before implantation as a strategy to prevent bacterial adhesion and biofilm formation. METHODS: After 24 hours of incubation with human osteogenic sarcoma SaOS-2 cells (1 × 10(5) cells/mL), the materials were incubated for 4...
March 7, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28266902/soluble-triggering-receptor-expressed-on-myeloid-cells-1-as-a-novel-marker-for-abdominal-sepsis
#4
Xiaofei Song, Yucheng Song, Xuedong Zhang, Huanzhou Xue
BACKGROUND: The aim of the study was to investigate the concentration and diagnostic significance of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) in acute abdominal conditions. METHODS: Plasma specimens were obtained from 68 patients with abdominal sepsis, 60 patients with systemic inflammatory response syndrome (SIRS), and 60 healthy individuals. The sepsis group was divided into the survival and death groups according to the 28-d outcome...
March 7, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28266900/right-colectomy-and-abdominal-perineal-resection-for-cancer-do-urinary-tract-infections-impact-outcomes
#5
John G Armstrong, Chien-Hsun Li, Junlin Liao, John C Byrn
BACKGROUND: We aim to assess the patient factors and concomitant infectious outcomes associated with urinary tract infection (UTI) occurrence and the impact of UTI on length of stay (LOS), re-admission, and death in a colorectal surgical population. PATIENTS AND METHODS: National Surgical Quality Improvement Program User Data for right colectomy and abdominal perineal resection (APR) procedures for cancer between 2006 and 2012 were analyzed. Concomitant infectious complications and timing of UTI diagnosis, inpatient versus outpatient, were considered...
March 7, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28177854/risk-factors-for-30-day-hospital-re-admission-with-an-infectious-complication-after-lower-extremity-vascular-procedures
#6
Joseph C Melvin, Jamie B Smith, Robin L Kruse, Todd R Vogel
BACKGROUND: Lowering the 30-d re-admission rate after vascular surgery offers the potential to improve healthcare quality. This study evaluated re-admission associated with infections after open and endovascular lower extremity (LE) procedures for peripheral artery disease (PAD). METHODS: Patients admitted for elective LE procedures for PAD were selected from the Cerner Health Facts(®) database. Chi-square analysis evaluated the characteristics of the index admission associated with infection at 30-d re-admission...
February 8, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28165882/role-of-combined-post-operative-venous-lactate-and-48-hours-c-reactive-protein-values-on-the-etiology-and-predictive-capacity-of-organ-space-surgical-site-infection-after-elective-colorectal-operation
#7
Montserrat Juvany, Xavier Guirao, Joan Carles Oliva, Jose M Badía Pérez
BACKGROUND: C-reactive protein (CRP) has been assessed to detect organ-space surgical site infection (OSI). Nevertheless, data about peri-operative oxygen debt and surgical stress-elicited biologic markers to explain and allow for the early detection of OSI are lacking. We analyzed immediate post-operative venous lactate, early CRP levels, and intra-operative hemodynamic values on the capacity to predict OSI after elective colorectal operation. PATIENTS AND METHODS: Patients undergoing an elective colorectal surgical procedure with anastomosis between March 2013 and August 2014 were included and assessed prospectively...
February 6, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28128684/aortic-graft-infections-after-emergency-and-non-emergency-reconstruction-incidence-treatment-and-long-term-outcome
#8
Jennifer Pettersson, Alireza Daryapeyma, Peter Gillgren, Rebecka Hultgren
BACKGROUND: Aortic graft infections (AGI) are rare, with an incidence of 0.6%-3% among patients with aortic grafts. Most previous reports are based on single-center material with limited follow-up. Because of the paucity of these cases, the optimal treatment remains unclear. A factor possibly affecting the mortality rate of these infections is whether the index procedure was emergency or elective. The aim of this study was to investigate the incidence of AGI and assess the long-term outcome after emergency and non-emergency aortic reconstruction in a large population...
January 27, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28099093/patients-with-infectious-endocarditis-and-drug-dependence-have-worse-clinical-outcomes-after-valvular-surgery
#9
Anthony Lemaire, Viktor Dombrovskiy, Siavash Saadat, George Batsides, Aziz Ghaly, Alan Spotnitz, Leonard Y Lee
BACKGROUND: Patients with infective endocarditis (IE) are at high risk for post-operative morbidity and death, which might be associated with drug abuse. The purpose of this study is to evaluate the impact of drug dependence on outcomes in patients who have IE and undergo valvular surgery (VS). PATIENTS AND METHODS: The Nationwide/National Inpatient Sample 2001-2012 was queried to select patients with IE who had elective VS using International Classification of Diseases, Ninth Revision, Clinical Modification diagnosis and procedure codes...
January 18, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28092497/polymyxin-b-hemoperfusion-for-sepsis-and-septic-shock-a-systematic-review-and-meta-analysis
#10
Takero Terayama, Kazuma Yamakawa, Yutaka Umemura, Morio Aihara, Satoshi Fujimi
BACKGROUND: To evaluate the efficacy and safety of direct hemoperfusion with polymyxin B-immobilized fiber (PMX-DHP) therapy in patients with sepsis. DESIGN: A systematic review and meta-analysis of four major databases: Cochrane Central Register of Controlled Trials, MEDLINE, Scopus, and Science Citation Index Expanded. STUDY SELECTION: Randomized controlled trials comparing PMX-DHP with conventional therapy on the outcome of mortality in patients with severe sepsis/septic shock...
January 16, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28085576/contact-isolation-precautions-in-trauma-patients-an-analysis-of-infectious-complications
#11
Mark E Hamill, Christopher R Reed, Sandy L Fogel, Eric H Bradburn, Kinga A Powers, Katie M Love, Christopher C Baker, Bryan R Collier
BACKGROUND: Victims of traumatic injuries represent a population at risk for a wide variety of complications. Contact isolation (CI) is a set of restrictions designed to help prevent the transmission of medically significant organisms in the healthcare setting. A growing body of literature demonstrates that CI can have significant implications for the individual isolated patient. Our goal was to characterize the use of contact isolation at our Level I trauma center and investigate the association of CI with infectious complications...
January 13, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28080292/effect-of-the-endoclear-%C3%A2-device-on-biofilm-in-endotracheal-tubes
#12
James M Bardes, Dana Gray, Alison Wilson
BACKGROUND: Organisms trapped in biofilms cause more than 80% of medical infections. Significant investments are being made to develop methods of removing these biofilms. The endOclear(®) device is reported to remove biofilm from endotracheal tubes (ETTs) and to decrease pneumonia rates and ventilator time. METHODS: This was an observational study performed at a university Level 1 trauma center intensive care unit. A series of 40 ETTs were collected at extubation, with half of the patients having been treated daily with the endOclear(®) device...
January 12, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28061321/effect-of-subcutaneous-sterile-vitamin-e-ointment-on-incisional-surgical-site-infection-after-elective-laparoscopic-colorectal-cancer-surgery
#13
David Alias, Jaime Ruiz-Tovar, Ana Moreno, Belen Manso, Gustavo Diaz, Manuel Duran, Damian Garcia-Olmo
BACKGROUND: Despite several interventions having been adopted to reduce the incidence of incisional surgical site infection (SSI), it still remains a challenge for surgeons, because incisional SSI is a common cause of health-care-associated infection, leading to increased morbidity, prolonged hospital stay, patient discomfort, and increased sanitary costs. The aim of this study was to evaluate the effect on incisional SSI of vitamin E ointment in the subcutaneous tissue of patients undergoing a laparoscopic colorectal surgical procedure...
January 6, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28212069/correction-to-surg-infect-2016-17-2-191-197
#14
(no author information available yet)
No abstract text is available yet for this article.
February 2017: Surgical Infections
https://www.readbyqxmd.com/read/28048964/variability-in-antibiotic-regimens-for-surgical-necrotizing-enterocolitis-highlights-the-need-for-new-guidelines
#15
Brian P Blackwood, Catherine J Hunter, Julia Grabowski
BACKGROUND: Necrotizing enterocolitis or NEC is the most common gastrointestinal emergency in the newborn. The etiology of NEC remains unknown, and treatment consists of antibiotic therapy and supportive care with the addition of surgical intervention as necessary. Unlike most surgical diseases, clear guidelines for the type and duration of peri-operative antibiotic therapy have not been established. Our aim was to review the antibiotic regimen(s) applied to surgical patients with NEC within a single neonatal intensive care unit (NICU) and to evaluate outcomes and help develop guidelines for antibiotic administration in this patient population...
February 2017: Surgical Infections
https://www.readbyqxmd.com/read/28048948/mechanism-of-injury-may-influence-infection-risk-from-early-blood-transfusion
#16
Charles A Karcutskie, Jonathan P Meizoso, Juliet J Ray, Davis B Horkan, Xiomara D Ruiz, Carl I Schulman, Nicholas Namias, Kenneth G Proctor
BACKGROUND: Blood transfusion is a known risk factor for infection in trauma patients. Differences based on mechanism of injury have not been well described. We hypothesize that infection risk in trauma patients with early blood transfusion is different based on blunt or penetrating mechanism of injury. PATIENTS AND METHODS: Adults admitted to the trauma intensive care unit from January 2010 through January 2015 were reviewed retrospectively. Those receiving transfusion after 24 h were excluded...
February 2017: Surgical Infections
https://www.readbyqxmd.com/read/28009535/optimizing-vancomycin-release-from-calcium-phosphate-based-cement-by-carboxymethyl-cellulose-for-prevention-of-osteomyelitis
#17
Boren Lin, Ciara Caldwell, Sarit Bhaduri, Vijay Goel, Anand Agarwal
No abstract text is available yet for this article.
February 2017: Surgical Infections
https://www.readbyqxmd.com/read/28005468/age-and-its-impact-on-outcomes-with-intra-abdominal-infection
#18
Drew Farmer, Jeffrey M Tessier, James M Sanders, Robert G Sawyer, Ori D Rotstein, E P Dellinger, Pamela A Lipsett, Joseph Cuschieri, Preston Miller, Charles H Cook, Christopher A Guidry, Reza Askari, Billy J Moore, Therese M Duane
BACKGROUND: Age has been shown to play a significant role in the etiology of complicated intra-abdominal infections (cIAIs), but the correlation between age and outcomes after therapy was not investigated in the Study to Optimize Peritoneal Infection Therapy (STOP-IT) trial. PATIENTS AND METHODS: Data were obtained by post hoc analysis of the STOP-IT trial database. Patients were stratified by age <65 or ≥65 years. Primary outcomes were surgical site infection (SSI), recurrent IAI (recIAI), and death...
February 2017: Surgical Infections
https://www.readbyqxmd.com/read/28004988/biosynthetic-grafts-to-replace-infected-prosthetic-vascular-bypasses-a-single-center-experience
#19
Ingolf Töpel, Theresa Stigler, Isabelle Ayx, Thomas Betz, Christian Uhl, Markus Steinbauer
BACKGROUND: There are only a few options to replace infected infrainguinal synthetic vascular grafts in the absence of suitable autologous veins. To use a biosynthetic vascular graft (Omniflow(®)II) might be a valuable alternative. METHODS: We retrospectively analyzed the clinical course of 29 patients who underwent replacement of an infected infrainguinal vascular prosthesis (Szilagyi 3) by an Omniflow(®)II graft. RESULTS: Because of the lack of suitable autologous veins, 15 above-knee femoro-popliteal, 5 below-knee femoro-popliteal, and 9 femoro-tibial bypasses were replaced with biosynthetic grafts...
February 2017: Surgical Infections
https://www.readbyqxmd.com/read/28004986/smoking-and-risk-of-surgical-site-infection-after-spinal-surgery-a-systematic-review-and-meta-analysis
#20
Lingde Kong, Zhao Liu, Fei Meng, Yong Shen
BACKGROUND: The effect of smoking on the risk of surgical site infection (SSI) after spinal surgery remains controversial. Therefore, we conducted a meta-analysis to determine whether there is an association between smoking and the risk of SSI and to calculate the relative risk of infections attributable to smoking. METHODS: We performed a literature search of cohort and case-control studies in the MEDLINE, Embase, and ISI Web of Science databases. Sensitivity and subgroup analyses were performed to test the robustness of overall estimates of risk and to investigate potential sources of heterogeneity...
February 2017: Surgical Infections
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