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Surgical Infections

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https://www.readbyqxmd.com/read/28792850/literature-review-of-criteria-for-defining-recipient-site-infection-after-oral-oncologic-surgery-with-simultaneous-reconstruction
#1
Masaya Akashi, Junya Kusumoto, Akiko Sakakibara, Kazunobu Hashikawa, Shungo Furudoi, Takahide Komori
BACKGROUND: The lack of uniformity of criteria for defining recipient-site infection after oral oncologic surgery with simultaneous reconstruction is problematic despite numerous studies on this issue. This study aimed to investigate the difference in the criteria for defining recipient-site infection after oral oncologic surgery with reconstruction. METHODS: A Medline search was performed via PUBMED using the following combinations of key terms that were tagged in the title, abstract, or both: "surgical site infection-head neck," "surgical site infection-oral cancer," "antibiotic prophylaxis-head neck," and "surgical site infection-oral carcinoma...
August 9, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28771110/temporary-intra-operative-portocaval-shunts-post-operative-infections-and-mid-term-survival-after-cava-sparing-liver-transplantation
#2
Maximilian Weniger, Joachim Andrassy, Thomas Weig, Beatrice Grabein, Alexander Crispin, Markus Rentsch, Christian Siebers, Alexandr Bazhin, Jan G D'Haese, Werner Hartwig, Jens Werner, Markus Guba, Eugen Faist, Sebastian Pratschke, Martin K Angele
BACKGROUND: Temporary intra-operative portocaval shunts (TPCS) are believed to improve outcomes after cava-sparing liver transplantation. We hypothesize that decompression of the portal venous system via a TPCS reduces gut congestion, thereby decreasing bacterial translocation. Thus, we sought to clarify whether transplantation with a TPCS alters rates of post-operative infections and survival. PATIENTS AND METHODS: Patients undergoing liver transplantation (n = 189) were stratified by usage of a TPCS and the type of intra-operative antibiotic prophylaxis...
August 3, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28759335/tubercular-abdominal-cocoon-systematic-review-of-an-uncommon-form-of-tuberculosis
#3
Vishal Sharma, Harjeet Singh, Harshal S Mandavdhare
BACKGROUND: Abdominal cocoon formation is an uncommon manifestation of abdominal tuberculosis that is characterized by the formation of a fibrous membrane-like sac around the small intestinal loops. Appropriate treatment and outcomes are uncertain Objectives: To review the clinical presentation, treatment, and outcomes for tubercular abdominal cocoon (TAC). PATIENTS AND METHODS: We included studies published in the English language and listed in EMBASE or PubMed...
July 31, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28759327/factors-of-pelvic-infection-and-death-in-patients-with-open-pelvic-fractures-and-rectal-injuries
#4
Wenhao Song, Dongsheng Zhou, Weicheng Xu, Guoming Zhang, Chunhui Wang, Daodi Qiu, Jinlei Dong
BACKGROUND: Open pelvic fractures associated with rectal injuries are uncommon. They often cause serious pelvic infection, even death. This combination of injuries has been reviewed infrequently. Herein, we report factors associated with pelvic infection and death in a group of patients with open pelvic fractures and concurrent rectal injuries. METHODS: We retrospectively reviewed the records of patients with open pelvic fractures and rectal injuries who were treated at our institution from January 2010-April 2014...
July 31, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28731836/mortality-rate-and-antibiotic-resistance-in-complicated-diverticulitis-report-of-272-consecutive-patients-worldwide-a-prospective-cohort-study
#5
Federico Coccolini, Mattia Trevisan, Giulia Montori, Massimo Sartelli, Fausto Catena, Marco Ceresoli, Antonio Costanzo, Arianna Heyer, Luca Ansaloni
BACKGROUND: Complicated diverticulitis (CD) is a common problem for surgeons. In treating it, as a general principle, every verified source of infection should be controlled. Supplementary antimicrobial management involves a delicate balance of optimizing empirical therapy while reducing unnecessary antibiotic use. The necessity to know the most frequent infecting pathogens and their spectra of resistance is becoming pivotal. The aim of this study was to determine the microbiologic profile of complicated intra-abdominal infections (IAIs) secondary to CD, to analyze the role of empirical antimicrobial therapy, and to describe the clinical aspects of CD worldwide...
July 21, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28686144/synovial-fluid-%C3%AE-defensin-as-a-biomarker-for-peri-prosthetic-joint-infection-a-systematic-review-and-meta-analysis
#6
Bin Li, Fei Chen, Yi Liu, Guokang Xu
BACKGROUND: Total joint arthroplasty (TJA) has been one of the most beneficial interventions for treating patients suffering from joint disorders. However, peri-prosthetic joint infection (PJI) is a serious complication that often accompanies TJA and the diagnosis of PJI is remains difficult. Questions remain regarding whether certain biomarkers can be valuable in the diagnosis of PJI. PATIENTS AND METHODS: We conducted our systematic review by searching PubMed, Embase, Web of Science, the Cochrane Library, and Science Direct with the key words "periprosthetic joint infection," "synovial fluid," and "α-defensin...
July 7, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28654355/a-prognostic-scoring-tool-for-cesarean-organ-space-surgical-site-infections-derivation-and-internal-validation
#7
Srisuda Assawapalanggool, Nongyao Kasatpibal, Supatra Sirichotiyakul, Rajin Arora, Watcharin Suntornlimsiri
BACKGROUND: Organ/space surgical site infections (SSIs) are serious complications after cesarean delivery. However, no scoring tool to predict these complications has yet been developed. This study sought to develop and validate a prognostic scoring tool for cesarean organ/space SSIs. METHODS: Data for case and non-case of cesarean organ/space SSI between January 1, 2007 and December 31, 2012 from a tertiary care hospital in Thailand were analyzed. Stepwise multivariable logistic regression was used to select the best predictor combination and their coefficients were transformed to a risk scoring tool...
June 27, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28650745/longer-duration-antimicrobial-therapy-does-not-prevent-treatment-failure-in-high-risk-patients-with-complicated-intra-abdominal-infections
#8
Taryn E Hassinger, Christopher A Guidry, Ori D Rotstein, Therese M Duane, Heather L Evans, Charles H Cook, Patrick J O'neill, John E Mazuski, Reza Askari, Lena M Napolitano, Nicholas Namias, Preston R Miller, E Patchen Dellinger, Raul Coimbra, Christine S Cocanour, Kaysie L Banton, Joseph Cuschieri, Kimberley Popovsky, Robert G Sawyer
BACKGROUND: Recent studies have suggested the length of treatment of intra-abdominal infections (IAIs) can be shortened without detrimental effects on patient outcomes. However, data from high-risk patient populations are lacking. We hypothesized that patients at high risk for treatment failure will benefit from a longer course of antimicrobial therapy. METHODS: Patients enrolled in the Study to Optimize Peritoneal Infection Therapy (STOP-IT) trial were evaluated retrospectively to identify risk factors associated with treatment failure, which was defined as the composite outcome of recurrent IAI, surgical site infection, or death...
June 26, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28650734/clostridium-difficile-associated-colitis-post-transplant-is-not-associated-with-elevation-of-tacrolimus-concentrations
#9
Hugo J R Bonatti, Karim W Sadik, Elizabeth Krebs, Costi D Sifri, Timothy L Pruett, Robert G Sawyer
BACKGROUND: Diarrhea is a common condition after solid organ transplant (SOT); Clostridium difficile-associated colitis (CDAC) is one of the most common infections after SOT. We documented previously that some types of enteritis are associated with an elevation of tacrolimus (TAC) trough concentrations by interfering with the drug's complex metabolism. PATIENTS AND METHODS: Tacrolimus concentrations of 25 SOT recipients including 12 renal and 13 liver recipients before, during, and after CDAC were analyzed retrospectively...
June 26, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28631985/effect-of-a-standardized-protocol-of-antibiotic-therapy-on-surgical-site-infection-after-laparoscopic-surgery-for-complicated-appendicitis
#10
Hyoung-Chul Park, Min Jeong Kim, Bong Hwa Lee
BACKGROUND: Although it is accepted that complicated appendicitis requires antibiotic therapy to prevent post-operative surgical infections, consensus protocols on the duration and regimens of treatment are not well established. This study aimed to compare the outcome of post-operative infectious complications in patients receiving old non-standardized and new standard antibiotic protocols, involving either 5 or 10 days of treatment, respectively. METHODS: We enrolled 1,343 patients who underwent laparoscopic surgery for complicated appendicitis between January 2009 and December 2014...
June 20, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28613991/microbial-characteristics-of-nosocomial-infections-and-their-association-with-the-utilization-of-hand-hygiene-products-a-hospital-wide-analysis-of-78-344-cases
#11
Song Liu, Meng Wang, Gefei Wang, Xiuwen Wu, Wenxian Guan, Jianan Ren
BACKGROUND: Nosocomial infections are the main adverse events during health care delivery. Hand hygiene is the fundamental strategy for the prevention of nosocomial infections. Microbial characteristics of nosocomial infections in the Asia-Pacific region have not been investigated fully. Correlation between the use of hand hygiene products and the incidence of nosocomial infections is still unknown. This study investigates the microbial characteristics of nosocomial infections in the Asia-Pacific region and analyzes the association between the utilization of hand hygiene products and the incidence of nosocomial infections...
June 14, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28581895/safety-and-efficacy-of-alginate-adhesion-barrier-gel-in-compromised-intestinal-anastomosis
#12
Ankit A Chaturvedi, Simon T K Yauw, Roger M L M Lomme, Thijs Hendriks, Harry van Goor
BACKGROUND: For any anti-adhesive barrier developed for abdominal surgery, the use under conditions in which anastomotic healing is compromised needs to be investigated. The current study evaluates the effect of a new ultrapure alginate gel on early healing of high-risk anastomoses in the ileum and compares this with the gold standard used in clinical practice. MATERIALS AND METHODS: In 75 adult male Wistar rats, a 5 mm ileal segment was resected and continuity was restored by construction of an inverted anastomosis...
June 5, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28557648/ventral-hernia-repair-a-meta-analysis-of-randomized-controlled-trials
#13
Julie L Holihan, Craig Hannon, Christopher Goodenough, Juan R Flores-Gonzalez, Kamal M Itani, Oscar Olavarria, Jiandi Mo, Tien C Ko, Lillian S Kao, Mike K Liang
BACKGROUND: From the patient's perspective, a ventral hernia (VH) can cause pain, adversely affect function, increase size, cosmetically distort the abdomen, and incarcerate/strangulate abdominal contents. The only known "cure" for a VH is surgical repair. The aim of this study was to review systematically the published randomized controlled trials (RCTs) of the surgical care of VH. METHOD: A search of the Ovid, MEDLINE, EMBASE, and Cochrane databases was performed to obtain reports of RCTs on the use of mesh reinforcement in abdominal wall hernia repair...
May 30, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28557559/aggressive-antimicrobial-initiation-for-suspected-intensive-care-unit-acquired-infection-is-associated-with-decreased-long-term-survival-after-critical-illness
#14
Christopher A Guidry, Tjasa Hranjec, Puja M Shah, Zachary C Dietch, Taryn E Hassinger, Nathan R Elwood, Robert G Sawyer
BACKGROUND: The long-term significance of early and prolonged antibiotic use in critically ill patients is yet to be described. Several studies suggest that antimicrobial exposure may have as yet unrecognized long-term effects on clinically meaningful outcomes. Our group previously conducted a quasi-experimental, before and after observational cohort study of hemodynamically stable surgical patients suspected of having an intensive care unit-acquired infection. This study demonstrated that aggressive initiation of antimicrobial therapy was associated with increased 30-day deaths...
May 30, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28537533/risk-of-infection-and-blood-transfusion-in-trauma
#15
Charles A Karcutskie, Nicholas Namias
No abstract text is available yet for this article.
May 24, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28537483/mechanism-of-injury-and-risk-from-early-blood-transfusion
#16
Beuy Joob, Viroj Wiwanitkit
No abstract text is available yet for this article.
May 24, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28654375/re-effect-of-the-endoclear-%C3%A2-device-on-biofilm-in-endotracheal-tubes
#17
James M Bardes, Dana Gray, Alison Wilson
No abstract text is available yet for this article.
July 2017: Surgical Infections
https://www.readbyqxmd.com/read/28614043/antibiotics-vs-appendectomy-for-acute-uncomplicated-appendicitis-in-adults-review-of-the-evidence-and-future-directions
#18
Jared M Huston, Lillian S Kao, Phillip K Chang, James M Sanders, Sara Buckman, Charles A Adams, Christine S Cocanour, Sarah E Parli, Julia Grabowski, Jose Diaz, Jeffrey M Tessier, Therese M Duane
BACKGROUND: Acute appendicitis is the most common abdominal surgical emergency in the United States, with a lifetime risk of 7%-8%. The treatment paradigm for complicated appendicitis has evolved over the past decade, and many cases now are managed by broad-spectrum antibiotics. We determined the role of non-operative and operative management in adult patients with uncomplicated appendicitis. METHODS: Several meta-analyses have attempted to clarify the debate. Arguably the most influential is the Appendicitis Acuta (APPAC) Trial...
July 2017: Surgical Infections
https://www.readbyqxmd.com/read/28561600/current-pneumonia-surveillance-methodology-similar-underestimation-in-trauma-and-surgical-patients-in-the-intensive-care-unit
#19
Brenda M Zosa, Joseph F Golob, Kristen J Conrad-Schnetz, David Schechtman, Laura A Kreiner, Jeffrey A Claridge
BACKGROUND: In 2013, the Centers for Disease Control and Prevention (CDC) developed new surveillance definitions for ventilator-associated events (VAE), leading to concerns that hospitals may be underreporting the true incidence of ventilator-associated pneumonias (VAPs). We sought to compare rates of clinically diagnosed VAP with CDC defined possible VAPs (PVAPs) in patients with a VAE in the surgical/trauma intensive care unit (STICU). HYPOTHESIS: Significant difference exists between rates of clinical VAP and PVAP in patients with at least one VAE...
July 2017: Surgical Infections
https://www.readbyqxmd.com/read/28557651/effects-of-a-new-hospital-wide-surgical-consultation-protocol-in-patients-with-clostridium-difficile-colitis
#20
Gwendolyn M van der Wilden, George C Velmahos, Yuchiao Chang, Ed Bajwa, Walter J O'Donnell, Kathleen Finn, N Stuart Harris, D Dante Yeh, David R King, Marc A de Moya, Peter J Fagenholz
BACKGROUND: Fulminant Clostridium difficile colitis (fCDC) occurs in 2%-8% of patients with CDC and carries a high death rate. Prompt operation may reduce death. Our aim was to determine whether a standardized hospital-wide protocol for surgical referral in CDC would result in earlier surgical consultation, earlier identification of patients who could benefit from surgical therapy, and reduced deaths from fCDC. METHODS: A multidisciplinary team developed consensus criteria for surgical consultation...
July 2017: Surgical Infections
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