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Surgical Infections

Jodie Morris, Natasha Kelly, Lisa Elliott, Andrea Grant, Matthew Wilkinson, Kaushik Hazratwala, Peter McEwen
BACKGROUND: Despite significant advancements in surgical protocols and biomaterials for orthopedics, peri-prosthetic joint infection (PJI) remains a leading cause of implant failure. Staphylococcus aureus nasal colonization is an established risk factor for PJI, with methicillin-sensitive S. aureus a leading cause of orthopedic implant-related infections. The purpose of these in vitro studies was to investigate the antibacterial activity of a tailored bacteriophage cocktail against planktonic and biofilm-associated S...
September 12, 2018: Surgical Infections
Viktor Gabriel, Areg Grigorian, Jacquelyn L Phillips, Sebastian D Schubl, Cristobal Barrios, Marija Pejcinovska, Eugene Won, Jeffry Nahmias
BACKGROUND: Clostridium difficile infection (CDI) is now the most common cause of health-care-associated infection and carries a mortality rate ranging from 5-30%. Previously, trauma patients in whom CDI developed were thought to represent a unique younger at-risk population. This study aimed to establish the incidence of CDI among adult trauma patients. We hypothesized that these patients would have increased risk of death, intensive care unit (ICU) length of stay (LOS), and hospital LOS compared with trauma patients without CDI...
September 11, 2018: Surgical Infections
Jared M Huston, Brian S Zuckerbraun, Laura J Moore, James M Sanders, Therese M Duane
BACKGROUND: Acute diverticulitis occurs in 25% of individuals with diverticular disease and is associated with significant morbidity and mortality rates. Disease severity is classified as uncomplicated or complicated, with the latter including perforation, fistula, obstruction, or distant abscess. Uncomplicated diverticulitis often improves without surgery or invasive therapies. Administration of antibiotics is a standard of care for treatment of acute uncomplicated diverticulitis. However, recent data suggest antibiotics do not influence outcomes significantly...
September 11, 2018: Surgical Infections
Cory R Evans, John P Sharpe, Joseph M Swanson, G Christopher Wood, Timothy C Fabian, Martin A Croce, Louis J Magnotti
BACKGROUND: An integral part of ventilator-associated pneumonia (VAP) therapy is the appropriate choice of empiric antibiotics. Our previous experience demonstrated adherence to an empiric therapy pathway was associated with only modest changes in organisms causing VAP. The purpose of the current study was to evaluate the impact of a restrictive antibiotic policy for VAP in trauma patients on the incidence and sensitivities of causative pathogens since the previous study. PATIENTS AND METHODS: Patients with VAP diagnosed on bronchoalveolar lavage since the previous study were stratified by age, gender, mechanism of injury, and injury severity...
September 11, 2018: Surgical Infections
Rahel Meier, Thomas Wirth, Esther Vögelin, Parham Sendi
BACKGROUND: Implant-related infections in hand surgery are dreaded complications, potentially leading to loss of finger joint function or amputation. Knowledge about the clinical presentation and treatment concepts of these infections is limited. The aim of this study is to present a consecutive series of patients with implant-related infections of the finger joints and wrist. PATIENTS AND METHODS: We identified 25 patients with 29 implant-related infections. Infections were categorized as osteosynthesis-related infections (ORIs) or arthroplasty-related infections (ARIs)...
September 7, 2018: Surgical Infections
Katsuki Danno, Chu Matsuda, Susumu Miyazaki, Takamichi Komori, Megumi Nakanishi, Masaaki Motoori, Masaki Kashiwazaki, Kazumasa Fujitani
BACKGROUND AND PURPOSE: For patients at high risk, such as those with lower-gastrointestinal perforations, it is important to establish a preventive method that reduces the incidence of surgical site infections (SSIs) significantly. We applied negative-pressure wound therapy (NPWT) as part of a delayed primary closure approach to prevent SSIs. This study evaluated the value of this technique. METHODS: We included prospectively 28 patients undergoing abdominal surgery for peritonitis caused by a lower-gastrointestinal perforation between May 2014 and November 2015...
September 5, 2018: Surgical Infections
Li-Xia Yin, Bao-Min Chen, Ge-Fei Zhao, Qi-Feng Yuan, Qi Xue, Ke Xu
BACKGROUND: Surgical site infection (SSI) surveillance has become increasingly important during the peri-operative period of esophagectomy with cervical anastomosis (McKeown esophagectomy). This study sought to clarify the risk factors for SSI and to develop a stratification scoring system to predict SSI after esophagectomy with cervical anastomosis. PATIENTS AND METHODS: All patients who underwent elective esophagectomy with cervical anastomosis were studied between January 2010 and December 2016 in the Chinese Academy of Medical Sciences Cancer Hospital (CAMS)...
September 5, 2018: Surgical Infections
Zaid Al-Qurayshi, Sarah M Baker, Meghan Garstka, Christopher Ducoin, Mary Killackey, Ronald L Nichols, Emad Kandil
BACKGROUND: Post-operative infection (POI) is a serious complication in all surgical disciplines and can derail a patient's treatment and recovery course. In this analysis, we examine national trends, risk factors, and costs associated with POI. METHODS: Using the Nationwide Inpatient Sample (NIS) for the years available for data analysis at the time of this study (2003-2010), we performed a cross-sectional study of adult (≥18 years) inpatients with POI and designated Clinical Classification Software (CCS) procedural class codes for the operations performed...
September 5, 2018: Surgical Infections
Gabriel Gonzalez, Esteban Montemayor, James M Sanders, Mandy Burton, Jeffrey M Tessier, Therese M Duane
BACKGROUND: Diverticulitis remains a common disease encountered in the acute care setting. Management strategies have been developed to guide treatment decisions based on imaging. By using a multi-faceted clinical pathway approach, a standardized method of diagnosing and categorizing disease severity can be performed in order to guide appropriate management. This study evaluated provider compliance with an institutional clinical pathway designed to guide management of diverticulitis. METHODS: An institutional clinical pathway was developed to manage diverticulitis, including radiologic classification, primary service line assignment, interventional strategies, and antimicrobial treatment...
September 4, 2018: Surgical Infections
Reham AlJehani, Mohammed Nassif, Nora Trabulsi, Arub Asiri, Oyoon AlGhofaily
BACKGROUND: We sought to evaluate the practice of double gloving among surgeons and to determine the factors that affect compliance with such practice at King Abdulaziz University Hospital (KAUH). METHODS: A survey was conducted among surgeons in active training from all departments at KAUH through the use of a questionnaire from May through July 2017. RESULTS: Of the 220 surgeons who worked at KAUH, 183 agreed to participate in the study for a response rate of 83...
August 24, 2018: Surgical Infections
Meresa Gebremedhin Weldu, Haileselasie Berhane, Negassie Berhe, Kebede Haile, Yosef Sibhatu, Tsehaynesh Gidey, Kahsay Amare, Hiwot Zelalem, Rahel Mezemir, Tsegay Hadgu, Kesete Birhane
BACKGROUND: Surgical site infections (SSIs) are the most common hospital-acquired infection among surgical patients and remains a major clinical issue. In Ethiopia, despite many studies, the magnitude and associated factors of SSIs are not well documented and differ among regions. The aim of this study was to identify the magnitude and associated factors of SSIs in Suhul Hospital, Northern Ethiopia. METHODS: An institution-based cross-sectional study was conducted from February 2-March 31, 2016, in Shire Suhul Hospital...
August 20, 2018: Surgical Infections
Cristina Mondelo García, José María Gutiérrez Urbón, Cristina Pérez Sanz, María Isabel Martín Herranz
BACKGROUND: There is extensive evidence of the efficacy of anti-microbial drugs in preventing infections from surgical efforts. Our objective was to describe the results obtained in our annual surgical antibiotic prophylaxis (SAP) audit in the years 2013-2017. METHODS: This was a retrospective observational study of SAP in surgical procedures carried out between 2013 and 2017 in a tertiary-level hospital. We examined the results from the services of general surgery, vascular surgery, neurosurgery, the breast unit, otolaryngology, maxillofacial surgery, traumatology, urology, pediatric surgery, gynecology, and plastic surgery...
August 10, 2018: Surgical Infections
Paul E Marik
BACKGROUND: In general, patients with sepsis die from the host response to the infecting pathogen rather than from the infecting pathogen itself. Four patterns of death have been identified in sepsis, namely vasoplegic shock, single-organ respiratory failure (acute respiratory distress syndrome [ARDS]), multi-system organ failure (MSOF), and persistent MSOF with ongoing inflammation and immunosuppression with recurrent infections (persistent inflammation-immunosuppression and catabolism syndrome [PICS])...
July 24, 2018: Surgical Infections
Jared A Forrester, Brittany Lynn Powell, Joseph D Forrester, Christina Fast, Thomas G Weiser
BACKGROUND: Surgical infections are a major cause of morbidity and mortality in low- and middle-income countries (LMICs). Inadequately reprocessed surgical instruments can be a vector for pathogens. Little has been published on the current state of surgical instrument reprocessing in LMICs. METHODS: We performed a scoping review of English-language articles in PubMed, Web of Science, and Google Scholar databases describing current methods, policies, and barriers to surgical instrument reprocessing in LMICs...
August 2018: Surgical Infections
Bradley Buck, David Fumo, Karan Arora, Samay Jain, Puneet Sindhwani
BACKGROUND: Ciprofloxacin is given to patients routinely prior to trans-rectal prostate biopsy. However bacterial resistance to this antibiotic has increased nationally resulting in increased infectious complications after prostate biopsy. In our study we aimed to quantify the percentage of older northwestern Ohio males harboring ciprofloxacin-resistant bacteria in the rectal vault and to assess if resistance is increasing over time. METHODS: After Institutional Review Board approval, a retrospective chart review of all patients who underwent rectal swab culture within the Department of Urology at The University of Toledo Medical Center between January 1, 2012 and December 31, 2015 was completed...
August 2018: Surgical Infections
(no author information available yet)
No abstract text is available yet for this article.
August 2018: Surgical Infections
Devin R Halleran, Amanda J Onwuka, Amy E Lawrence, Beth C Fischer, Katherine J Deans, Peter C Minneci
BACKGROUND: Laser hair depilation has shown promise in small series of patients with pilonidal sinus disease. The purpose of this study was to review the published literature on laser hair depilation in pilonidal disease to determine its effect on disease recurrence. METHODS: The PubMed, Embase, and Cochrane Central Register of Controlled Trials databases were searched to identify all studies published through December 1, 2017 that examined the role of laser hair depilation in the treatment of pilonidal sinus disease...
August 2018: Surgical Infections
Oliver S Eng, Mustafa Raoof, Michael P O'Leary, Michael W Lew, Mark T Wakabayashi, I Benjamin Paz, Laleh G Melstrom, Byrne Lee
BACKGROUND: Maintenance of peri-operative normothermia remains a global quality metric for hospitals. Hypothermia is associated with surgical site infections (SSIs) in colorectal surgery. Patients undergoing cytoreductive surgery (CRS) with hyperthermic intra-peritoneal chemotherapy (HIPEC) can experience multiple complications post-operatively. We sought to investigate the association of peri-operative hypothermia with SSIs in patients undergoing CRS/HIPEC at our institution. PATIENTS AND METHODS: Patients undergoing CRS/HIPEC from 2009-2017 were identified retrospectively from a prospectively collected institutional database...
August 2018: Surgical Infections
Addison K May
No abstract text is available yet for this article.
August 2018: Surgical Infections
Harjeet Singh, Gautham Krishnamurthy, Jayapal Rajendran, Vishal Sharma, Harshal Mandavdhare, Hemanth Kumar, Thakur Deen Yadav, Rakesh Kumar Vasishta, Rajinder Singh
BACKGROUND: The role of surgery in abdominal tuberculosis is being redefined, as many patients will be candidates for endoscopic dilatation rather than open surgery. METHODS: A retrospective analysis was done of the surgical procedures performed in patients with abdominal tuberculosis in a large tertiary-care center in North India. Details such as clinical presentations, previous history of tuberculosis, any anti-tubercular therapy (ATT), Mantoux skin test results, and the surgical procedures and findings were recorded...
August 2018: Surgical Infections
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