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Journal of Cardiovascular Magnetic Resonance

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https://www.readbyqxmd.com/read/27931223/pattern-and-prognostic-value-of-cardiac-involvement-in-patients-with-late-onset-pompe-disease-a-comprehensive-cardiovascular-magnetic-resonance-approach
#1
Matthias Boentert, Anca Florian, Bianca Dräger, Peter Young, Ali Yilmaz
BACKGROUND: Pompe disease is an autosomal recessive disorder caused by deficiency of the lysosomal α-1,4-glucosidase leading to accumulation of glycogen in target tissues with progressive organ failure. While the early infantile-onset form is characterized by early severe hypertrophic cardiomyopathy with cardiac and respiratory failure, clinically relevant cardiomyopathy seems to be uncommon in patients with late-onset Pompe disease, and the prevalence and nature of myocardial abnormalities are still to be clarified...
December 7, 2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27908279/co-existing-intracranial-and-extracranial-carotid-artery-atherosclerotic-plaques-and-recurrent-stroke-risk-a-three-dimensional-multicontrast-cardiovascular-magnetic-resonance-study
#2
Yilan Xu, Chun Yuan, Zechen Zhou, Le He, Donghua Mi, Rui Li, Yuanyuan Cui, Yilong Wang, Yongjun Wang, Gaifen Liu, Zhuozhao Zheng, Xihai Zhao
BACKGROUND: As a systemic disease, atherosclerosis commonly affects intracranial and extracranial carotid arteries simultaneously which is defined as co-existing plaques. Previous studies demonstrated that co-existing atherosclerotic diseases are significantly associated with ischemic cerebrovascular events. The aim of this study was to investigate the characteristics of co-existing intracranial and extracranial carotid atherosclerotic plaques and their relationships with recurrent stroke by using 3D multi-contrast magnetic resonance (MR) vessel wall imaging...
December 2, 2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27899132/cardiac-t1-mapping-and-extracellular-volume-ecv-in-clinical-practice-a-comprehensive-review
#3
REVIEW
Philip Haaf, Pankaj Garg, Daniel R Messroghli, David A Broadbent, John P Greenwood, Sven Plein
Cardiovascular Magnetic Resonance is increasingly used to differentiate the aetiology of cardiomyopathies. Late Gadolinium Enhancement (LGE) is the reference standard for non-invasive imaging of myocardial scar and focal fibrosis and is valuable in the differential diagnosis of ischaemic versus non-ischaemic cardiomyopathy. Diffuse fibrosis may go undetected on LGE imaging. Tissue characterisation with parametric mapping methods has the potential to detect and quantify both focal and diffuse alterations in myocardial structure not assessable by LGE...
November 30, 2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27890014/chagas-heart-disease-gender-differences-in-myocardial-damage-assessed-by-cardiovascular-magnetic-resonance
#4
Antonildes N Assunção, Michael Jerosch-Herold, Rodrigo L Melo, Alejandra V Mauricio, Liliane Rocha, Jorge A Torreão, Fabio Fernandes, Barbara M Ianni, Charles Mady, José A F Ramires, Roberto Kalil-Filho, Carlos E Rochitte
BACKGROUND: Since a male-related higher cardiovascular morbidity and mortality in patients with Chagas' heart disease has been reported, we aimed to investigate gender differences in myocardial damage assessed by cardiovascular magnetic resonance (CMR). METHODS AND RESULTS: Retrospectively, 62 seropositive Chagas' heart disease patients referred to CMR (1.5 T) and with low probability of having significant coronary artery disease were included in this analysis...
November 28, 2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27884152/use-of-self-gated-radial-cardiovascular-magnetic-resonance-to-detect-and-classify-arrhythmias-atrial-fibrillation-and-premature-ventricular-contraction
#5
Eve Piekarski, Teodora Chitiboi, Rebecca Ramb, Li Feng, Leon Axel
BACKGROUND: Arrhythmia can significantly alter the image quality of cardiovascular magnetic resonance (CMR); automatic detection and sorting of the most frequent types of arrhythmias during the CMR acquisition could potentially improve image quality. New CMR techniques, such as non-Cartesian CMR, can allow self-gating: from cardiac motion-related signal changes, we can detect cardiac cycles without an electrocardiogram. We can further use this data to obtain a surrogate for RR intervals (valley intervals: VV)...
November 25, 2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27876066/in-vivo-cardiovascular-magnetic-resonance-of-2d-vessel-wall-diffusion-anisotropy-in-carotid-arteries
#6
Peter Opriessnig, Harald Mangge, Rudolf Stollberger, Hannes Deutschmann, Gernot Reishofer
BACKGROUND: Diffusion weighted (DW) cardiovascular magnetic resonance (CMR) has shown great potential to discriminate between healthy and diseased vessel tissue by evaluating the apparent diffusion coefficient (ADC) along the arterial axis. Recently, ex vivo studies on porcine arteries utilizing diffusion tensor imaging (DTI) revealed a circumferential fiber orientation rather than an organization in axial direction, suggesting dominant diffusion perpendicular to the slice direction. In the present study, we propose a method to access tangential and radial diffusion of carotids in vivo by utilizing a pulse sequence that enables high resolution DW imaging in combination with a two-dimensional (2D) diffusion gradient direction sampling scheme perpendicular to the longitudinal axis of the artery...
November 23, 2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27866473/top-100-cited-articles-in-cardiovascular-magnetic-resonance-a-bibliometric-analysis
#7
REVIEW
Muhammad Shahzeb Khan, Waqas Ullah, Irbaz Bin Riaz, Nizar Bhulani, Warren J Manning, Srini Tridandapani, Faisal Khosa
BACKGROUND: With limited health care resources, bibliometric studies can help guide researchers and research funding agencies towards areas where reallocation or increase in research activity is warranted. Bibliometric analyses have been published in many specialties and sub-specialties but our literature search did not reveal a bibliometric analysis on Cardiovascular Magnetic Resonance (CMR). The main objective of the study was to identify the trends of the top 100 cited articles on CMR research...
November 21, 2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27855705/myocardial-t1-mapping-at-3t-using-saturation-recovery-reference-values-precision-and-comparison-with-molli
#8
Sebastian Weingärtner, Nadja M Meßner, Johannes Budjan, Dirk Loßnitzer, Uwe Mattler, Theano Papavassiliu, Frank G Zöllner, Lothar R Schad
BACKGROUND: Myocardial T1-mapping recently emerged as a promising quantitative method for non-invasive tissue characterization in numerous cardiomyopathies. Commonly performed with an inversion-recovery (IR) magnetization preparation at 1.5T, the application at 3T has gained due to increased quantification precision. Alternatively, saturation-recovery (SR) T1-mapping has recently been introduced at 1.5T for improved accuracy. Thus, the purpose of this study is to investigate the robustness and precision of SR T1-mapping at 3T and to establish accurate reference values for native T1-times and extracellular volume fraction (ECV) of healthy myocardium...
November 18, 2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27846845/relationship-between-native-papillary-muscle-t1-time-and-severity-of-functional-mitral-regurgitation-in-patients-with-non-ischemic-dilated-cardiomyopathy
#9
Shingo Kato, Shiro Nakamori, Sébastien Roujol, Francesca N Delling, Shadi Akhtari, Jihye Jang, Tamer Basha, Sophie Berg, Kraig V Kissinger, Beth Goddu, Warren J Manning, Reza Nezafat
BACKGROUND: Functional mitral regurgitation is one of the severe complications of non-ischemic dilated cardiomyopathy (DCM). Non-contrast native T1 mapping has emerged as a non-invasive method to evaluate myocardial fibrosis. We sought to evaluate the potential relationship between papillary muscle T1 time and mitral regurgitation in DCM patients. METHODS: Forty DCM patients (55 ± 13 years) and 20 healthy adult control subjects (54 ± 13 years) were studied...
November 16, 2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27846914/review-of-journal-of-cardiovascular-magnetic-resonance-2015
#10
REVIEW
D J Pennell, A J Baksi, S K Prasad, R H Mohiaddin, F Alpendurada, S V Babu-Narayan, J E Schneider, D N Firmin
There were 116 articles published in the Journal of Cardiovascular Magnetic Resonance (JCMR) in 2015, which is a 14 % increase on the 102 articles published in 2014. The quality of the submissions continues to increase. The 2015 JCMR Impact Factor (which is published in June 2016) rose to 5.75 from 4.72 for 2014 (as published in June 2015), which is the highest impact factor ever recorded for JCMR. The 2015 impact factor means that the JCMR papers that were published in 2013 and 2014 were cited on average 5...
November 15, 2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27839514/objective-criteria-for-septal-fibrosis-in-non-ischemic-dilated-cardiomyopathy-validation-for-the-prediction-of-future-cardiovascular-events
#11
Yoko Mikami, Aidan Cornhill, Bobak Heydari, Sebastien X Joncas, Fahad Almehmadi, Mohammed Zahrani, Mahmoud Bokhari, John Stirrat, Raymond Yee, Naeem Merchant, Carmen P Lydell, Andrew G Howarth, James A White
BACKGROUND: Expert subjective reporting of mid-wall septal fibrosis on late gadolinium enhancement (LGE) images has been shown to predict major cardiovascular outcomes in patients with non-ischemic dilated cardiomyopathy (NIDCM). This study aims to establish objective criteria for non-experts to report clinically relevant septal fibrosis and compare its performance by such readers versus experts for the prediction of cardiovascular events. METHODS: LGE cardiovascular magnetic resonance (CMR) was performed in 118 consecutive patients with NIDCM (mean age 57 ± 14, 42 % female) and the presence of septal fibrosis scored by expert readers...
November 14, 2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27832796/antecedent-hypertension-and-myocardial-injury-in-patients-with-reperfused-st-elevation-myocardial-infarction
#12
Sebastian J Reinstadler, Thomas Stiermaier, Charlotte Eitel, Mohammed Saad, Bernhard Metzler, Suzanne de Waha, Georg Fuernau, Steffen Desch, Holger Thiele, Ingo Eitel
BACKGROUND: Antecedent hypertension is associated with poor outcome in patients with ST-elevation myocardial infarction (STEMI). Whether differences in myocardial salvage, infarct size and microvascular injury contribute to the adverse outcome is unknown. We investigated the association between antecedent hypertension and cardiovascular magnetic resonance (CMR) parameters of myocardial salvage and damage in a multicenter CMR substudy of the AIDA-STEMI trial (Abciximab Intracoronary versus intravenously Drug Application in ST-elevation myocardial infarction)...
November 11, 2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27842548/infarct-size-following-complete-revascularization-in-patients-presenting-with-stemi-a-comparison-of-immediate-and-staged-in-hospital-non-infarct-related-artery-pci-subgroups-in-the-cvlprit-study
#13
Jamal N Khan, Sheraz A Nazir, John P Greenwood, Miles Dalby, Nick Curzen, Simon Hetherington, Damian J Kelly, Daniel Blackman, Arne Ring, Charles Peebles, Joyce Wong, Thiagarajah Sasikaran, Marcus Flather, Howard Swanton, Anthony H Gershlick, Gerry P McCann
BACKGROUND: The CvLPRIT study showed a trend for improved clinical outcomes in the complete revascularisation (CR) group in those treated with an immediate, as opposed to staged in-hospital approach in patients with multivessel coronary disease undergoing primary percutaneous intervention (PPCI). We aimed to assess infarct size and left ventricular function in patients undergoing immediate compared with staged CR for multivessel disease at PPCI. METHODS: The Cardiovascular Magnetic Resonance (CMR) substudy of CvLPRIT was a multicentre, prospective, randomized, open label, blinded endpoint trial in PPCI patients with multivessel disease...
November 9, 2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27817748/dark-blood-late-enhancement-imaging
#14
Peter Kellman, Hui Xue, Laura J Olivieri, Russell R Cross, Elena K Grant, Marianna Fontana, Martin Ugander, James C Moon, Michael S Hansen
BACKGROUND: Bright blood late gadolinium enhancement (LGE) imaging typically achieves excellent contrast between infarcted and normal myocardium. However, the contrast between the myocardial infarction (MI) and the blood pool is frequently suboptimal. A large fraction of infarctions caused by coronary artery disease are sub-endocardial and thus adjacent to the blood pool. It is not infrequent that sub-endocardial MIs are difficult to detect or clearly delineate. METHODS: In this present work, an inversion recovery (IR) T2 preparation was combined with single shot steady state free precession imaging and respiratory motion corrected averaging to achieve dark blood LGE images with good signal to noise ratio while maintaining the desired spatial and temporal resolution...
November 7, 2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27814739/benefits-of-chronic-total-coronary-occlusion-percutaneous-intervention-in-patients-with-heart-failure-and-reduced-ejection-fraction-insights-from-a-cardiovascular-magnetic-resonance-study
#15
Montserrat Cardona, Victoria Martín, Susanna Prat-Gonzalez, José Tomás Ortiz, Rosario Jesús Perea, Teresa Maria de Caralt, Mónica Masotti, Félix Pérez-Villa, Manel Sabaté
BACKGROUND: Chronic total occlusion percutaneous coronary intervention (CTO-PCI) can improve angina and left ventricular ejection fraction (LVEF). These benefits were not assessed in populations with heart failure with reduced ejection fraction (HFrEF). We studied the effect of CTO-PCI on left ventricular function and clinical parameters in patients with HFrEF. METHODS: Using cardiovascular magnetic resonance (CMR), we studied 29 patients with HFrEF and evidence of viability and/or ischemia in the territory supplied by a CTO who were successfully treated with CTO-PCI...
November 5, 2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27809867/coronary-microvascular-function-and-myocardial-fibrosis-in-women-with-angina-pectoris-and-no-obstructive-coronary-artery-disease-the-ipower-study
#16
Naja Dam Mygind, Marie Mide Michelsen, Adam Pena, Abbas Ali Qayyum, Daria Frestad, Thomas Emil Christensen, Adam Ali Ghotbi, Nynne Dose, Rebekka Faber, Niels Vejlstrup, Philip Hasbak, Andreas Kjaer, Eva Prescott, Jens Kastrup
BACKGROUND: Even in absence of obstructive coronary artery disease women with angina pectoris have a poor prognosis possibly due to coronary microvascular disease. Coronary microvascular disease can be assessed by transthoracic Doppler echocardiography measuring coronary flow velocity reserve (CFVR) and by positron emission tomography measuring myocardial blood flow reserve (MBFR). Diffuse myocardial fibrosis can be assessed by cardiovascular magnetic resonance (CMR) T1 mapping. We hypothesized that coronary microvascular disease is associated with diffuse myocardial fibrosis...
November 4, 2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27802802/improved-high-resolution-pediatric-vascular-cardiovascular-magnetic-resonance-with-gadofosveset-enhanced-3d-respiratory-navigated-inversion-recovery-prepared-gradient-echo-readout-imaging-compared-to-3d-balanced-steady-state-free-precession-readout-imaging
#17
Animesh Tandon, Sassan Hashemi, W James Parks, Michael S Kelleman, Denver Sallee, Timothy C Slesnick
BACKGROUND: Improved delineation of vascular structures is a common indication for cardiovascular magnetic resonance (CMR) in children and requires high spatial resolution. Currently, pre-contrast 3D, respiratory navigated, T2-prepared, fat saturated imaging with a bSSFP readout (3D bSSFP) is commonly used; however, these images can be limited by blood pool inhomogeneity and exaggeration of metal artifact. We compared image quality of pediatric vasculature obtained using standard 3D bSSFP to 3D, respiratory navigated, inversion recovery prepared imaging with a gradient echo readout (3D IR GRE) performed after administration of gadofosveset trisodium (GT), a blood pool contrast agent...
November 2, 2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27788681/native-t1-values-identify-myocardial-changes-and-stratify-disease-severity-in-patients-with-duchenne-muscular-dystrophy
#18
Laura J Olivieri, Peter Kellman, Robert J McCarter, Russell R Cross, Michael S Hansen, Christopher F Spurney
BACKGROUND: Duchenne muscular dystrophy (DMD) is an X-linked, inherited disorder causing dilated cardiomyopathy with variable onset and progression. Currently we lack objective markers of the effect of therapies targeted towards preventing progression of subclinical cardiac disease. Thus, our aim was to compare the ability of native T1 and extracellular volume (ECV) measurements to differentiate risk of myocardial disease in DMD and controls. METHODS: Twenty boys with DMD and 16 age/gender-matched controls without history predisposing to cardiac fibrosis, but with a clinical indication for cardiovascular magnetic resonance (CMR) evaluation, underwent CMR with contrast...
October 28, 2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27782857/increased-left-ventricular-myocardial-extracellular-volume-is-associated-with-longer-cardiopulmonary-bypass-times-biventricular-enlargement-and-reduced-exercise-tolerance-in-children-after-repair-of-tetralogy-of-fallot
#19
Eugénie Riesenkampff, Wietske Luining, Mike Seed, Paweena Chungsomprasong, Cedric Manlhiot, Bernadette Elders, Brian W McCrindle, Shi-Joon Yoo, Lars Grosse-Wortmann
BACKGROUND: Unfavorable left ventricular (LV) remodelling may be associated with adverse outcomes after Tetralogy of Fallot (TOF) repair. We sought to assess T1 cardiovascular magnetic resonance (CMR) markers of diffuse LV myocardial fibrosis in children after TOF repair, and associated factors. METHODS: In this prospective, cross-sectional study, native (=non-contrast) T1 times and extracellular volume fraction (ECV) were quantified in the LV myocardium using CMR...
October 26, 2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27765061/cardiovascular-magnetic-resonance-patterns-of-biopsy-proven-cardiac-involvement-in-systemic-sclerosis
#20
Patrick Krumm, Karin A L Mueller, Karin Klingel, Ulrich Kramer, Marius S Horger, Tanja Zitzelsberger, Reinhard Kandolf, Meinrad Gawaz, Konstantin Nikolaou, Bernhard D Klumpp, Joerg C Henes
BACKGROUND: To determine morphological and functional cardiovascular magnetic resonance (CMR) patterns in histopathologically confirmed myocardial involvement in patients with systemic sclerosis (SSc). METHODS: Twenty patients (6 females; mean age 41 ± 11 years) with histopathologically proven cardiac involvement in SSc in the years 2008-2016 were retrospectively evaluated. Morphological, functional and late gadolinium enhancement (LGE) images were acquired in standard angulations at 1...
October 21, 2016: Journal of Cardiovascular Magnetic Resonance
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