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Journal of Cardiovascular Magnetic Resonance

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https://www.readbyqxmd.com/read/28231838/continuous-measurement-of-aortic-dimensions-in-turner-syndrome-a-cardiovascular-magnetic-resonance-study
#1
Dhananjay Radhakrishnan Subramaniam, William A Stoddard, Kristian H Mortensen, Steffen Ringgaard, Christian Trolle, Claus H Gravholt, Ephraim J Gutmark, Goutham Mylavarapu, Philippe F Backeljauw, Iris Gutmark-Little
BACKGROUND: Severity of thoracic aortic disease in Turner syndrome (TS) patients is currently described through measures of aorta size and geometry at discrete locations. The objective of this study is to develop an improved measurement tool that quantifies changes in size and geometry over time, continuously along the length of the thoracic aorta. METHODS: Cardiovascular magnetic resonance (CMR) scans for 15 TS patients [41 ± 9 years (mean age ± standard deviation (SD))] were acquired over a 10-year period and compared with ten healthy gender and age-matched controls...
February 24, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28222749/the-impact-of-trans-catheter-aortic-valve-replacement-induced-left-bundle-branch-block-on-cardiac-reverse-remodeling
#2
Laura E Dobson, Tarique A Musa, Akhlaque Uddin, Timothy A Fairbairn, Owen J Bebb, Peter P Swoboda, Philip Haaf, James Foley, Pankaj Garg, Graham J Fent, Christopher J Malkin, Daniel J Blackman, Sven Plein, John P Greenwood
BACKGROUND: Left bundle branch block (LBBB) is common following trans-catheter aortic valve replacement (TAVR) and has been linked to increased mortality, although whether this is related to less favourable cardiac reverse remodeling is unclear. The aim of the study was to investigate the impact of TAVR induced LBBB on cardiac reverse remodeling. METHODS: 48 patients undergoing TAVR for severe aortic stenosis were evaluated. 24 patients with new LBBB (LBBB-T) following TAVR were matched with 24 patients with a narrow post-procedure QRS (nQRS)...
February 22, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28215181/effect-of-cellular-and-extracellular-pathology-assessed-by-t1-mapping-on-regional-contractile-function-in-hypertrophic-cardiomyopathy
#3
Peter P Swoboda, Adam K McDiarmid, Bara Erhayiem, Graham R Law, Pankaj Garg, David A Broadbent, David P Ripley, Tarique A Musa, Laura E Dobson, James R Foley, Graham J Fent, Stephen P Page, John P Greenwood, Sven Plein
BACKGROUND: Regional contractile dysfunction is a frequent finding in hypertrophic cardiomyopathy (HCM). We aimed to investigate the contribution of different tissue characteristics in HCM to regional contractile dysfunction. METHODS: We prospectively recruited 50 patients with HCM who underwent cardiovascular magnetic resonance (CMR) studies at 3.0 T including cine imaging, T1 mapping and late gadolinium enhancement (LGE) imaging. For each segment of the American Heart Association model segment thickness, native T1, extracellular volume (ECV), presence of LGE and regional strain (by feature tracking and tissue tagging) were assessed...
February 20, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28209163/cardiovascular-magnetic-resonance-myocardial-feature-tracking-using-a-non-rigid-elastic-image-registration-algorithm-assessment-of-variability-in-a-real-life-clinical-setting
#4
Pedro Morais, Alberto Marchi, Julie A Bogaert, Tom Dresselaers, Brecht Heyde, Jan D'hooge, Jan Bogaert
BACKGROUND: Cardiovascular magnetic resonance myocardial feature tracking (CMR-FT) is a promising technique for quantification of myocardial strain from steady-state free precession (SSFP) cine images. We sought to determine the variability of CMR-FT using a non-rigid elastic registration algorithm recently available in a commercial software package (Segment, Medviso) in a real-life clinical setting. METHODS: Firstly, we studied the variability in a healthy volunteer who underwent 10 CMR studies over five consecutive days...
February 17, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28196494/assessment-of-myocardial-injury-after-reperfused-infarction-by-t1%C3%AF-cardiovascular-magnetic-resonance
#5
Rutger H Stoffers, Marie Madden, Mohammed Shahid, Francisco Contijoch, Joseph Solomon, James J Pilla, Joseph H Gorman, Robert C Gorman, Walter R T Witschey
BACKGROUND: The evolution of T1ρ and of other endogenous contrast methods (T2, T1) in the first month after reperfused myocardial infarction (MI) is uncertain. We conducted a study of reperfused MI in pigs to serially monitor T1ρ, T2 and T1 relaxation, scar size and transmurality at 1 and 4 weeks post-MI. METHODS: Ten Yorkshire swine underwent 90 min of occlusion of the circumflex artery and reperfusion. T1ρ, T2 and native T1 maps and late gadolinium enhanced (LGE) cardiovascular magnetic resonance (CMR) data were collected at 1 week (n = 10) and 4 weeks (n = 5)...
February 15, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28222756/proximal-aortic-stiffening-in-turner-patients-may-be-present-before-dilation-can-be-detected-a-segmental-functional-mri-study
#6
Daniel G H Devos, Katya De Groote, Danilo Babin, Laurent Demulier, Yves Taeymans, Jos J Westenberg, Luc Van Bortel, Patrick Segers, Eric Achten, Jean De Schepper, Ernst Rietzschel
BACKGROUND: To study segmental structural and functional aortic properties in Turner syndrome (TS) patients. Aortic abnormalities contribute to increased morbidity and mortality of women with Turner syndrome. Cardiovascular magnetic resonance (CMR) allows segmental study of aortic elastic properties. METHOD: We performed Pulse Wave Velocity (PWV) and distensibility measurements using CMR of the thoracic and abdominal aorta in 55 TS-patients, aged 13-59y, and in a control population (n = 38;12-58y)...
February 13, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28183320/real-time-phase-contrast-flow-cardiovascular-magnetic-resonance-with-low-rank-modeling-and-parallel-imaging
#7
Aiqi Sun, Bo Zhao, Yunduo Li, Qiong He, Rui Li, Chun Yuan
BACKGROUND: Conventional phase-contrast cardiovascular magnetic resonance (PC-CMR) employs cine-based acquisitions to assess blood flow condition, in which electro-cardiogram (ECG) gating and respiration control are generally required. This often results in lower acquisition efficiency, and limited utility in the presence of cardiovascular pathology (e.g., cardiac arrhythmia). Real-time PC-CMR, without ECG gating and respiration control, is a promising alternative that could overcome limitations of the conventional approach...
February 10, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28173819/cardiovascular-magnetic-resonance-evaluation-of-symptomatic-severe-aortic-stenosis-association-of-circumferential-myocardial-strain-and-mortality
#8
Tarique Al Musa, Akhlaque Uddin, Peter P Swoboda, Timothy A Fairbairn, Laura E Dobson, Anvesha Singh, Pankaj Garg, Christopher D Steadman, Bara Erhayiem, Ananth Kidambi, David P Ripley, Adam K McDiarmid, Philip Haaf, Daniel J Blackman, Sven Plein, Gerald P McCann, John P Greenwood
BACKGROUND: It is unknown whether circumferential strain is associated with prognosis after treatment of aortic stenosis (AS). We aimed to characterise strain in severe AS, using myocardial tagging cardiovascular magnetic resonance (CMR), prior to and following Transcatheter Aortic Valve Implantation (TAVI) and Surgical Aortic Valve Replacement (SAVR), and determine whether abnormalities in strain were associated with outcome. METHODS: CMR was performed pre- and 6 m post-intervention in 98 patients (52 TAVI, 46 SAVR; 77 ± 8 years) with severe AS...
February 8, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28162089/transient-left-atrial-dysfunction-is-a-feature-of-takotsubo-syndrome
#9
Thomas Stiermaier, Tobias Graf, Christian Möller, Charlotte Eitel, Jakob Ledwoch, Steffen Desch, Matthias Gutberlet, Gerhard Schuler, Holger Thiele, Ingo Eitel
BACKGROUND: Takotsubo syndrome (TTS) is characterized by a transient left and/or right ventricular dysfunction as a consequence of a distinctive pattern of regional wall motion abnormalities. However, a systematic evaluation of the left atrial (LA) function in patients with TTS is lacking. The aim of the present study was therefore to comprehensively assess LA performance indexes and function in patients with TTS. METHODS: We compared LA function assessed by volumetric indexes derived from fractional volume changes in cardiovascular magnetic resonance (CMR) between 125 TTS patients and 125 patients with anterior ST-segment elevation myocardial infarction (STEMI)...
February 6, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28178995/reference-ranges-for-cardiac-structure-and-function-using-cardiovascular-magnetic-resonance-cmr-in-caucasians-from-the-uk-biobank-population-cohort
#10
Steffen E Petersen, Nay Aung, Mihir M Sanghvi, Filip Zemrak, Kenneth Fung, Jose Miguel Paiva, Jane M Francis, Mohammed Y Khanji, Elena Lukaschuk, Aaron M Lee, Valentina Carapella, Young Jin Kim, Paul Leeson, Stefan K Piechnik, Stefan Neubauer
BACKGROUND: Cardiovascular magnetic resonance (CMR) is the gold standard method for the assessment of cardiac structure and function. Reference ranges permit differentiation between normal and pathological states. To date, this study is the largest to provide CMR specific reference ranges for left ventricular, right ventricular, left atrial and right atrial structure and function derived from truly healthy Caucasian adults aged 45-74. METHODS: Five thousand sixty-five UK Biobank participants underwent CMR using steady-state free precession imaging at 1...
February 3, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28143545/histological-validation-of-cardiovascular-magnetic-resonance-t1-mapping-markers-of-myocardial-fibrosis-in-paediatric-heart-transplant-recipients
#11
Seiko Ide, Eugenie Riesenkampff, David A Chiasson, Anne I Dipchand, Paul F Kantor, Rajiv R Chaturvedi, Shi-Joon Yoo, Lars Grosse-Wortmann
BACKGROUND: Adverse fibrotic remodeling is detrimental to myocardial health and a reliable method for monitoring the development of fibrotic remodeling may be desirable during the follow-up of patients after heart transplantation (HTx). Quantification of diffuse myocardial fibrosis with cardiovascular magnetic resonance (CMR) has been increasingly applied and validated histologically in adult patients with heart disease. However, comparisons of CMR findings with histological fibrosis burden in children are lacking...
February 1, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28132648/experimental-validation-of-contrast-enhanced-ssfp-cine-cmr-for-quantification-of-myocardium-at-risk-in-acute-myocardial-infarction
#12
David Nordlund, Mikael Kanski, Robert Jablonowski, Sasha Koul, David Erlinge, Marcus Carlsson, Henrik Engblom, Anthony H Aletras, Håkan Arheden
BACKGROUND: Accurate assessment of myocardium at risk (MaR) after acute myocardial infarction (AMI) is necessary when assessing myocardial salvage. Contrast-enhanced steady-state free precession (CE-SSFP) is a recently developed cardiovascular magnetic resonance (CMR) method for assessment of MaR up to 1 week after AMI. Our aim was to validate CE-SSFP for determination of MaR in an experimental porcine model using myocardial perfusion single-photon emission computed tomography (MPS) as a reference standard and to test the stability of MaR-quantification over time after injecting gadolinium-based contrast...
January 30, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28125995/analysis-of-spatiotemporal-fidelity-in-quantitative-3d-first-pass-perfusion-cardiovascular-magnetic-resonance
#13
Lukas Wissmann, Alexander Gotschy, Claudio Santelli, Kerem Can Tezcan, Sandra Hamada, Robert Manka, Sebastian Kozerke
BACKGROUND: Whole-heart first-pass perfusion cardiovascular magnetic resonance (CMR) relies on highly accelerated image acquisition. The influence of undersampling on myocardial blood flow (MBF) quantification has not been systematically investigated yet. In the present work, the effect of spatiotemporal scan acceleration on image reconstruction accuracy and MBF error was studied using a numerical phantom and validated in-vivo. METHODS: Up to 10-fold scan acceleration using k-t PCA and k-t SPARSE-SENSE was simulated using the MRXCAT CMR numerical phantom framework...
January 27, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28143574/feasibility-of-real-time-mr-thermal-dose-mapping-for-predicting-radiofrequency-ablation-outcome-in-the-myocardium-in-vivo
#14
Solenn Toupin, Pierre Bour, Matthieu Lepetit-Coiffé, Valéry Ozenne, Baudouin Denis de Senneville, Rainer Schneider, Alexis Vaussy, Arnaud Chaumeil, Hubert Cochet, Frédéric Sacher, Pierre Jaïs, Bruno Quesson
BACKGROUND: Clinical treatment of cardiac arrhythmia by radiofrequency ablation (RFA) currently lacks quantitative and precise visualization of lesion formation in the myocardium during the procedure. This study aims at evaluating thermal dose (TD) imaging obtained from real-time magnetic resonance (MR) thermometry on the heart as a relevant indicator of the thermal lesion extent. METHODS: MR temperature mapping based on the Proton Resonance Frequency Shift (PRFS) method was performed at 1...
January 25, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28110638/assessing-exercise-cardiac-reserve-using-real-time-cardiovascular-magnetic-resonance
#15
Thu-Thao Le, Jennifer Ann Bryant, Alicia Er Ting, Pei Yi Ho, Boyang Su, Raymond Choon Chye Teo, Julian Siong-Jin Gan, Yiu-Cho Chung, Declan P O'Regan, Stuart A Cook, Calvin Woon-Loong Chin
BACKGROUND: Exercise cardiovascular magnetic resonance (ExCMR) has great potential for clinical use but its development has been limited by a lack of compatible equipment and robust real-time imaging techniques. We developed an exCMR protocol using an in-scanner cycle ergometer and assessed its performance in differentiating athletes from non-athletes. METHODS: Free-breathing real-time CMR (1.5T Aera, Siemens) was performed in 11 athletes (5 males; median age 29 [IQR: 28-39] years) and 16 age- and sex-matched healthy volunteers (7 males; median age 26 [interquartile range (IQR): 25-33] years)...
January 23, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28187739/the-global-cardiovascular-magnetic-resonance-registry-gcmr-of-the-society-for-cardiovascular-magnetic-resonance-scmr-its-goals-rationale-data-infrastructure-and-current-developments
#16
Raymond Y Kwong, Steffen E Petersen, Jeanette Schulz-Menger, Andrew E Arai, Scott E Bingham, Yucheng Chen, Yuna L Choi, Ricardo C Cury, Vanessa M Ferreira, Scott D Flamm, Kevin Steel, W Patricia Bandettini, Edward T Martin, Leelakrishna Nallamshetty, Stefan Neubauer, Subha V Raman, Erik B Schelbert, Uma S Valeti, Jie Jane Cao, Nathaniel Reichek, Alistair A Young, Lyuba Fexon, Misha Pivovarov, Victor A Ferrari, Orlando P Simonetti
BACKGROUND: With multifaceted imaging capabilities, cardiovascular magnetic resonance (CMR) is playing a progressively increasing role in the management of various cardiac conditions. A global registry that harmonizes data from international centers, with participation policies that aim to be open and inclusive of all CMR programs, can support future evidence-based growth in CMR. METHODS: The Global CMR Registry (GCMR) was established in 2013 under the auspices of the Society for Cardiovascular Magnetic Resonance (SCMR)...
January 20, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28095878/black-blood-thrombus-imaging-bti-a-contrast-free-cardiovascular-magnetic-resonance-approach-for-the-diagnosis-of-non-acute-deep-vein-thrombosis
#17
Guoxi Xie, Hanwei Chen, Xueping He, Jianke Liang, Wei Deng, Zhuonan He, Yufeng Ye, Qi Yang, Xiaoming Bi, Xin Liu, Debiao Li, Zhaoyang Fan
BACKGROUND: Deep vein thrombosis (DVT) is a common but elusive illness that can result in long-term disability or death. Accurate detection of thrombosis and assessment of its size and distribution are critical for treatment decision-making. In the present study, we sought to develop and evaluate a cardiovascular magnetic resonance (CMR) black-blood thrombus imaging (BTI) technique, based on delay alternating with nutation for tailored excitation black-blood preparation and variable flip angle turbo-spin-echo readout, for the diagnosis of non-acute DVT...
January 18, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28088917/effects-of-heart-valve-prostheses-on-phase-contrast-flow-measurements-in-cardiovascular-magnetic-resonance-a-phantom-study
#18
Johanna Richau, Matthias A Dieringer, Julius Traber, Florian von Knobelsdorff-Brenkenhoff, Andreas Greiser, Carsten Schwenke, Jeanette Schulz-Menger
BACKGROUND: Cardiovascular Magnetic Resonance is often used to evaluate patients after heart valve replacement. This study systematically analyses the influence of heart valve prostheses on phase contrast measurements in a phantom trial. METHODS: Two biological and one mechanical aortic valve prostheses were integrated in a flow phantom. B0 maps and phase contrast measurements were acquired at a 1.5 T MR scanner using conventional gradient-echo sequences in predefined distances to the prostheses...
January 16, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28081721/splenic-t1-mapping-a-novel-quantitative-method-for-assessing-adenosine-stress-adequacy-for-cardiovascular-magnetic-resonance
#19
Alexander Liu, Rohan S Wijesurendra, Rina Ariga, Masliza Mahmod, Eylem Levelt, Andreas Greiser, Mario Petrou, George Krasopoulos, John C Forfar, Rajesh K Kharbanda, Keith M Channon, Stefan Neubauer, Stefan K Piechnik, Vanessa M Ferreira
BACKGROUND: Perfusion cardiovascular magnetic resonance (CMR) performed with inadequate adenosine stress leads to false-negative results and suboptimal clinical management. The recently proposed marker of adequate stress, the "splenic switch-off" sign, detects splenic blood flow attenuation during stress perfusion (spleen appears dark), but can only be assessed after gadolinium first-pass, when it is too late to optimize the stress response. Reduction in splenic blood volume during adenosine stress is expected to shorten native splenic T1, which may predict splenic switch-off without the need for gadolinium...
January 13, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28122618/submillimeter-diffusion-tensor-imaging-and-late-gadolinium-enhancement-cardiovascular-magnetic-resonance-of-chronic-myocardial-infarction
#20
Farhad Pashakhanloo, Daniel A Herzka, Susumu Mori, Muz Zviman, Henry Halperin, Neville Gai, David A Bluemke, Natalia A Trayanova, Elliot R McVeigh
BACKGROUND: Knowledge of the three-dimensional (3D) infarct structure and fiber orientation remodeling is essential for complete understanding of infarct pathophysiology and post-infarction electromechanical functioning of the heart. Accurate imaging of infarct microstructure necessitates imaging techniques that produce high image spatial resolution and high signal-to-noise ratio (SNR). The aim of this study is to provide detailed reconstruction of 3D chronic infarcts in order to characterize the infarct microstructural remodeling in porcine and human hearts...
January 11, 2017: Journal of Cardiovascular Magnetic Resonance
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