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Journal of Cardiovascular Magnetic Resonance

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https://www.readbyqxmd.com/read/28806996/improved-passive-catheter-tracking-with-positive-contrast-for-cmr-guided-cardiac-catheterization-using-partial-saturation-psat
#1
Mari Nieves Velasco Forte, Kuberan Pushparajah, Tobias Schaeffter, Israel Valverde Perez, Kawal Rhode, Bram Ruijsink, Mazen Alhrishy, Nicholas Byrne, Amedeo Chiribiri, Tevfik Ismail, Tarique Hussain, Reza Razavi, Sébastien Roujol
BACKGROUND: Cardiac catheterization is a common procedure in patients with congenital heart disease (CHD). Although cardiovascular magnetic resonance imaging (CMR) represents a promising alternative approach to fluoroscopy guidance, simultaneous high contrast visualization of catheter, soft tissue and the blood pool remains challenging. In this study, a novel passive tracking technique is proposed for enhanced positive contrast visualization of gadolinium-filled balloon catheters using partial saturation (pSAT) magnetization preparation...
August 15, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28800739/sources-of-variability-in-quantification-of-cardiovascular-magnetic-resonance-infarct-size-reproducibility-among-three-core-laboratories
#2
Igor Klem, Einar Heiberg, Lowie Van Assche, Michele A Parker, Han W Kim, John D Grizzard, Håkan Arheden, Raymond J Kim
BACKGROUND: Acute myocardial infarct (AMI) size depicted by late gadolinium enhancement cardiovascular magnetic resonance (CMR) is increasingly used as an efficacy endpoint in randomized trials comparing AMI therapies. Infarct size is quantified using manual planimetry (MANUAL), visual scoring (VISUAL), or automated techniques using signal-intensity thresholding (AUTO). Although AUTO is considered the most reproducible, prior studies did not account for the subjective determination of endocardial/epicardial borders, which all methods require...
August 11, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28784140/patterns-of-cmr-measured-longitudinal-strain-and-its-association-with-late-gadolinium-enhancement-in-patients-with-cardiac-amyloidosis-and-its-mimics
#3
Lynne K Williams, Julian F Forero, Zoran B Popovic, Dermot Phelan, Diego Delgado, Harry Rakowski, Bernd J Wintersperger, Paaladinesh Thavendiranathan
BACKGROUND: Regional variability of longitudinal strain (LS) has been previously described with echocardiography in patients with cardiac amyloidosis (CA), however, the reason for this variability is not completely evident. We sought to describe regional patterns in LS using feature-tracking software applied to cardiovascular magnetic resonance (CMR) cine images in patients with CA, hypertrophic cardiomyopathy (HCM), and Anderson-Fabry's disease (AFD) and to relate these patterns to the distribution of late gadolinium enhancement (LGE)...
August 7, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28768519/synthetic-hematocrit-derived-from-the-longitudinal-relaxation-of-blood-can-lead-to-clinically-significant-errors-in-measurement-of-extracellular-volume-fraction-in-pediatric-and-young-adult-patients
#4
Frank J Raucci, David A Parra, Jason T Christensen, Lazaro E Hernandez, Larry W Markham, Meng Xu, James C Slaughter, Jonathan H Soslow
BACKGROUND: Extracellular volume fraction (ECV) is altered in pathological cardiac remodeling and predicts death and arrhythmia. ECV can be quantified using cardiovascular magnetic resonance (CMR) T1 mapping but calculation requires a measured hematocrit (Hct). The longitudinal relaxation of blood has been used in adults to generate a synthetic Hct (estimate of true Hct) but has not been validated in pediatric populations. METHODS: One hundred fourteen children and young adults underwent a total of 163 CMRs with T1 mapping...
August 2, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28768517/automated-assessments-of-circumferential-strain-from-cine-cmr-correlate-with-lvef-declines-in-cancer-patients-early-after-receipt-of-cardio-toxic-chemotherapy
#5
Marie-Pierre Jolly, Jennifer H Jordan, Giselle C Meléndez, Gary R McNeal, Ralph B D'Agostino, W Gregory Hundley
BACKGROUND: In patients with cancer receiving potentially cardio-toxic chemotherapy, measurements of left ventricular (LV) circumferential or longitudinal strain are often used clinically to identify myocardial dysfunction. Using a new software algorithm, we sought to determine in individuals receiving treatment for cancer the association between automated assessments of LV mean mid-wall circumferential strain and conventional measures of LV ejection fraction (EF) both obtained from cardiovascular magnetic resonance (CMR) cine balanced steady-state free-precession (bSSFP) white-blood acquisitions...
August 2, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28764773/quantification-of-both-the-area-at-risk-and-acute-myocardial-infarct-size-in-st-segment-elevation-myocardial-infarction-using-t1-mapping
#6
Heerajnarain Bulluck, Matthew Hammond-Haley, Marianna Fontana, Daniel S Knight, Alex Sirker, Anna S Herrey, Charlotte Manisty, Peter Kellman, James C Moon, Derek J Hausenloy
BACKGROUND: A comprehensive cardiovascular magnetic resonance (CMR) in reperfused ST-segment myocardial infarction (STEMI) patients can be challenging to perform and can be time-consuming. We aimed to investigate whether native T1-mapping can accurately delineate the edema-based area-at-risk (AAR) and post-contrast T1-mapping and synthetic late gadolinium (LGE) images can quantify MI size at 1.5 T. Conventional LGE imaging and T2-mapping could then be omitted, thereby shortening the scan duration...
August 1, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28750642/cmr-fluoroscopy-right-heart-catheterization-for-cardiac-output-and-pulmonary-vascular-resistance-results-in-102-patients
#7
Toby Rogers, Kanishka Ratnayaka, Jaffar M Khan, Annette Stine, William H Schenke, Laurie P Grant, Jonathan R Mazal, Elena K Grant, Adrienne Campbell-Washburn, Michael S Hansen, Rajiv Ramasawmy, Daniel A Herzka, Hui Xue, Peter Kellman, Anthony Z Faranesh, Robert J Lederman
BACKGROUND: Quantification of cardiac output and pulmonary vascular resistance (PVR) are critical components of invasive hemodynamic assessment, and can be measured concurrently with pressures using phase contrast CMR flow during real-time CMR guided cardiac catheterization. METHODS: One hundred two consecutive patients underwent CMR fluoroscopy guided right heart catheterization (RHC) with simultaneous measurement of pressure, cardiac output and pulmonary vascular resistance using CMR flow and the Fick principle for comparison...
July 27, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28750637/quantification-of-myocardium-at-risk-in-st-elevation-myocardial-infarction-a-comparison-of-contrast-enhanced-steady-state-free-precession-cine-cardiovascular-magnetic-resonance-with-coronary-angiographic-jeopardy-scores
#8
Rodney De Palma, Peder Sörensson, Dinos Verouhis, John Pernow, Nawzad Saleh
BACKGROUND: Clinical outcome following acute myocardial infarction is predicted by final infarct size evaluated in relation to left ventricular myocardium at risk (MaR). Contrast-enhanced steady-state free precession (CE-SSFP) cardiovascular magnetic resonance imaging (CMR) is not widely used for assessing MaR. Evidence of its utility compared to traditional assessment methods and as a surrogate for clinical outcome is needed. METHODS: Retrospective analysis within a study evaluating post-conditioning during ST elevation myocardial infarction (STEMI) treated with coronary intervention (n = 78)...
July 27, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28750632/impact-of-bileaflet-mitral-valve-prolapse-on-quantification-of-mitral-regurgitation-with-cardiac-magnetic-resonance-a-single-center-study
#9
Gabriella Vincenti, Pier Giorgio Masci, Tobias Rutz, Jonathan De Blois, Milan Prša, Xavier Jeanrenaud, Juerg Schwitter, Pierre Monney
BACKGROUND: To quantify mitral regurgitation (MR) with CMR, the regurgitant volume can be calculated as the difference between the left ventricular (LV) stroke volume (SV) measured with the Simpson's method and the reference SV, i.e. the right ventricular SV (RVSV) in patients without tricuspid regurgitation. However, for patients with prominent mitral valve prolapse (MVP), the Simpson's method may underestimate the LV end-systolic volume (LVESV) as it only considers the volume located between the apex and the mitral annulus, and neglects the ventricular volume that is displaced into the left atrium but contained within the prolapsed mitral leaflets at end systole...
July 27, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28724418/improved-recovery-of-regional-left-ventricular-function-after-pci-of-chronic-total-occlusion-in-stemi-patients-a-cardiovascular-magnetic-resonance-study-of-the-randomized-controlled-explore-trial
#10
Joëlle Elias, Ivo M van Dongen, Loes P Hoebers, Dagmar M Ouweneel, Bimmer E P M Claessen, Truls Råmunddal, Peep Laanmets, Erlend Eriksen, René J van der Schaaf, Dan Ioanes, Robin Nijveldt, Jan G Tijssen, Alexander Hirsch, José P S Henriques
BACKGROUND: The Evaluating Xience and left ventricular function in PCI on occlusiOns afteR STEMI (EXPLORE) trial did not show a significant benefit of percutaneous coronary intervention (PCI) of the concurrent chronic total occlusion (CTO) in ST-segment elevation myocardial infarction (STEMI) patients on global left ventricular (LV) systolic function. However a possible treatment effect will be most pronounced in the CTO territory. Therefore, we aimed to study the effect of CTO PCI compared to no-CTO PCI on the recovery of regional LV function, particularly in the CTO territory...
July 19, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28720123/cardiovascular-magnetic-resonance-in-an-adult-human-population-serial-observations-from-the-multi-ethnic-study-of-atherosclerosis
#11
REVIEW
Kihei Yoneyama, Bharath A Venkatesh, David A Bluemke, Robyn L McClelland, João A C Lima
The Multi-Ethnic Study of Atherosclerosis (MESA) is the first large-scale multi-ethnic population study in the U.S. to use advanced cardiovascular magnetic resonance (CMR) imaging. MESA participants were free of cardiovascular disease at baseline between 2000 and 2002, and were followed up between 2009 and 2011 with repeated CMR examinations as part of MESA. CMR allows the clinician to visualize and accurately quantify volume and dimensions of all four cardiac chambers; measure systolic and diastolic ventricular function; assess myocardial fibrosis; assess vessel lumen size, vessel wall morphology, and vessel stiffness...
July 18, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28679397/local-coronary-wall-eccentricity-and-endothelial-function-are-closely-related-in-patients-with-atherosclerotic-coronary-artery-disease
#12
Allison G Hays, Micaela Iantorno, Michael Schär, Monica Mukherjee, Matthias Stuber, Gary Gerstenblith, Robert G Weiss
BACKGROUND: Coronary endothelial function (CEF) in patients with coronary artery disease (CAD) varies among coronary segments in a given patient. Because both coronary vessel wall eccentricity and coronary endothelial dysfunction are predictors of adverse outcomes, we hypothesized that local coronary endothelial dysfunction is associated with local coronary artery eccentricity. METHODS: We used 3 T coronary CMR to measure CEF as changes in coronary cross-sectional area (CSA) and coronary blood flow (CBF) during isometric handgrip exercise (IHE), a known endothelial-dependent stressor, in 29 patients with known CAD and 16 healthy subjects...
July 6, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28676061/hemorrhage-promotes-inflammation-and-myocardial-damage-following-acute-myocardial-infarction-insights-from-a-novel-preclinical-model-and-cardiovascular-magnetic-resonance
#13
Nilesh R Ghugre, Mihaela Pop, Reuben Thomas, Susan Newbigging, Xiuling Qi, Jennifer Barry, Bradley H Strauss, Graham A Wright
BACKGROUND: Myocardial hemorrhage is a frequent complication following reperfusion in acute myocardial infarction and is predictive of adverse outcomes. However, it remains unsettled whether hemorrhage is simply a marker of a severe initial ischemic insult or directly contributes to downstream myocardial damage. Our objective was to evaluate the contribution of hemorrhage towards inflammation, microvascular obstruction and infarct size in a novel porcine model of hemorrhagic myocardial infarction using cardiovascular magnetic resonance (CMR)...
July 4, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28662717/nonenhanced-mr-angiography-of-the-pulmonary-arteries-using-single-shot-radial-quiescent-interval-slice-selective-qiss-a-technical-feasibility-study
#14
Robert R Edelman, Robert I Silvers, Kiran H Thakrar, Mark D Metzl, Jose Nazari, Shivraman Giri, Ioannis Koktzoglou
BACKGROUND: For evaluation of the pulmonary arteries in patients suspected of pulmonary embolism, CT angiography (CTA) is the first-line imaging test with contrast-enhanced MR angiography (CEMRA) a potential alternative. Disadvantages of CTA include exposure to ionizing radiation and an iodinated contrast agent, while CEMRA is sensitive to respiratory motion and requires a gadolinium-based contrast agent. The primary goal of our technical feasibility study was to evaluate pulmonary arterial conspicuity using breath-hold and free-breathing implementations of a recently-developed nonenhanced approach, single-shot radial quiescent-interval slice-selective (QISS) MRA...
June 30, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28659144/impaired-right-ventricular-contractile-function-in-childhood-obesity-and-its-association-with-right-and-left-ventricular-changes-a-cine-dense-cardiac-magnetic-resonance-study
#15
Linyuan Jing, Arichanah Pulenthiran, Christopher D Nevius, Abba Mejia-Spiegeler, Jonathan D Suever, Gregory J Wehner, H Lester Kirchner, Christopher M Haggerty, Brandon K Fornwalt
BACKGROUND: Pediatric obesity is a growing public health problem, which is associated with increased risk of cardiovascular disease and premature death. Left ventricular (LV) remodeling (increased myocardial mass and thickness) and contractile dysfunction (impaired longitudinal strain) have been documented in obese children, but little attention has been paid to the right ventricle (RV). We hypothesized that obese/overweight children would have evidence of RV remodeling and contractile dysfunction...
June 28, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28645326/improving-visualization-of-4d-flow-cardiovascular-magnetic-resonance-with-four-dimensional-angiographic-data-generation-of-a-4d-phase-contrast-magnetic-resonance-cardioangiography-4d-pc-mrca
#16
Mariana Bustamante, Vikas Gupta, Carl-Johan Carlhäll, Tino Ebbers
Magnetic Resonance Angiography (MRA) and Phase-Contrast MRA (PC-MRA) approaches used for assessment of cardiovascular morphology typically result in data containing information from the entire cardiac cycle combined into one 2D or 3D image. Information specific to each timeframe of the cardiac cycle is, however, lost in this process. This study proposes a novel technique, called Phase-Contrast Magnetic Resonance CardioAngiography (4D PC-MRCA), that utilizes the full potential of 4D Flow CMR when generating temporally resolved PC-MRA data to improve visualization of the heart and major vessels throughout the cardiac cycle...
June 23, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28637508/hyperpolarized-13-c-urea-myocardial-first-pass-perfusion-imaging-using-velocity-selective-excitation
#17
Maximilian Fuetterer, Julia Busch, Sophie M Peereboom, Constantin von Deuster, Lukas Wissmann, Miriam Lipiski, Thea Fleischmann, Nikola Cesarovic, Christian T Stoeck, Sebastian Kozerke
BACKGROUND: A velocity-selective binomial excitation scheme for myocardial first-pass perfusion measurements with hyperpolarized (13)C substrates, which preserves bolus magnetization inside the blood pool, is presented. The proposed method is evaluated against gadolinium-enhanced (1)H measurements in-vivo. METHODS: The proposed excitation with an echo-planar imaging readout was implemented on a clinical CMR system. Dynamic myocardial stress perfusion images were acquired in six healthy pigs after bolus injection of hyperpolarized (13)C urea with the velocity-selective vs...
June 21, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28424090/targeted-endomyocardial-biopsy-guided-by-real-time-cardiovascular-magnetic-resonance
#18
Christina Unterberg-Buchwald, Christian Oliver Ritter, Verena Reupke, Robin Niklas Wilke, Christine Stadelmann, Michael Steinmetz, Andreas Schuster, Gerd Hasenfuß, Joachim Lotz, Martin Uecker
BACKGROUND: Endomyocardial biopsies (EMB) are an important diagnostic tool for myocarditis and other infiltrative cardiac diseases. Routinely, biopsies are obtained under fluoroscopic guidance with a substantial radiation burden. Despite procedural success, there is a large sampling error caused by missing the affected myocardium. Therefore, multiple (>6) biopsies are taken in the clinical setting. In cardiovascular magnetic resonance (CMR), late gadolinium enhancement (LGE) depicts areas of affected myocardium in myocarditis or in other infiltrative cardiomyopathies...
April 19, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28395671/longitudinal-assessment-of-right-ventricular-structure-and-function-by-cardiovascular-magnetic-resonance-in-breast-cancer-patients-treated-with-trastuzumab-a-prospective-observational-study
#19
Ashita Barthur, Christine Brezden-Masley, Kim A Connelly, Vinita Dhir, Kelvin K W Chan, Rashida Haq, Anish Kirpalani, Joseph J Barfett, Laura Jimenez-Juan, Gauri R Karur, Djeven P Deva, Andrew T Yan
BACKGROUND: There are limited data on the effects of trastuzumab on the right ventricle (RV). Therefore, we sought to evaluate the temporal changes in right ventricular (RV) structure and function as measured by cardiovascular magnetic resonance (CMR), and their relationship with left ventricular (LV) structure and function in breast cancer patients treated with trastuzumab. METHODS: Prospective, longitudinal, observational study involving 41 women with HER2+ breast cancer who underwent serial CMR at baseline, 6, 12, and 18 months after initiation of trastuzumab...
April 10, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28385161/myocardial-perfusion-cardiovascular-magnetic-resonance-optimized-dual-sequence-and-reconstruction-for-quantification
#20
Peter Kellman, Michael S Hansen, Sonia Nielles-Vallespin, Jannike Nickander, Raquel Themudo, Martin Ugander, Hui Xue
BACKGROUND: Quantification of myocardial blood flow requires knowledge of the amount of contrast agent in the myocardial tissue and the arterial input function (AIF) driving the delivery of this contrast agent. Accurate quantification is challenged by the lack of linearity between the measured signal and contrast agent concentration. This work characterizes sources of non-linearity and presents a systematic approach to accurate measurements of contrast agent concentration in both blood and myocardium...
April 7, 2017: Journal of Cardiovascular Magnetic Resonance
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