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Brazilian Journal of Infectious Diseases

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https://www.readbyqxmd.com/read/29782827/prevalence-and-risk-factors-of-mild-chronic-renal-failure-in-hiv-infected-patients-influence-of-female-gender-and-antiretroviral-therapy
#1
Marina Pontello Cristelli, Joan Carles Trullàs, Federico Cofán, Naira Rico, Christian Manzardo, Juan Ambrosioni, Josep Lluis Bedini, Asunción Moreno, Fritz Diekmann, Jose Maria Miro
BACKGROUND: In people living with HIV, much is known about chronic kidney disease, defined as a glomerular filtration rate under 60mL/min. However, there is scarce data about prevalence and risk factors for milder impairment (60-89mL/min). OBJECTIVE: The present study aims to assess the influence of sex, antiretroviral therapy, and classical risk factors on the occurrence of mild decreased renal function in a large Spanish cohort of HIV-infected patients. METHODS: Cross-sectional, single center study, including all adult HIV-1-infected patients under antiretroviral treatment with at least two serum creatinine measures during 2014, describing the occurrence of and the risk factors for mildly decreased renal function (eGFR by CKD-EPI creatinine equation of 60-89mL/min)...
May 18, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29752892/high-vertical-hiv-transmission-rate-in-the-midwest-region-of-brazil
#2
Vanessa Terezinha Gubert de Matos, Fabiani de Morais Batista, Naiara Valera Versage, Clarice Souza Pinto, Vanessa Marcon de Oliveira, Érica Freire de Vasconcelos Pereira, Roberta Barbeta Dos Rios de Matos, Márcia Maria Ferrairo Janini Dal Fabbro, Ana Lúcia Lyrio de Oliveira
OBJECTIVES: To estimate vertical HIV transmission rate in a capital city of the Midwest region of Brazil and describe the factors related to transmission. METHODS: A descriptive epidemiological study based on the analysis of secondary data from the Notifiable Diseases Information System (SINAN). The analysis considered all HIV-infected pregnant women with delivery in Campo Grande-MS in the years 2007-2013 and their HIV-exposed infants. RESULTS: A total of 218 births of 176 HIV-infected pregnant women were identified during the study period, of which 187 infants were exposed and uninfected, 19 seroconverted, and 12 were still inconclusive in July 2015...
May 9, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29752891/effectiveness-and-tolerability-of-direct-acting-antivirals-for-chronic-hepatitis-c-patients-in-a-southern-state-of-brazil
#3
Vinicius Lins Ferreira, Helena Hiemisch Lobo Borba, Astrid Wiens, Maria Lucia Alves Pedroso, Vanessa Ferreira de Camargo Radunz, Cláudia Alexandra Pontes Ivantes, Aline Satie Oba Kuniyoshi, Roberto Pontarolo
BACKGROUND: This study aimed to evaluate the clinical effectiveness in terms of sustained virological response (SVR) and tolerability of available second generation direct-acting antivirals (DAAs) in Brazilian patients. METHODS: This was a retrospective observational study conducted in six centers in Southern Brazil. The sample comprised adult patients who were chronically infected with hepatitis C virus (HCV), regardless of virus genotype, fibrosis stage, or prior treatment...
May 9, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29684320/initial-evaluation-of-universal-immunization-with-a-single-dose-against-hepatitis-a-virus-in-central-brazil
#4
Wagner Izidoro de Brito, Eduardo Rodrigues Alves-Junior, Rode Martinho de Oliveira, Francisco José Dutra Souto
Vaccination against the hepatitis A virus (HAV) administered in two doses has been used effectively in universal child immunization programs in several countries. A single-dose vaccination was adopted in some low-income countries in an attempt to reduce costs without losing effectiveness. In 2014, single-dose universal vaccination was introduced in Brazil for children aged two years. Since such strategy is still not universally accepted, its efficacy should be compared to the two-dose strategy. To assess the humoral response after the single-dose HAV vaccination schedule, a cross-sectional study was conducted in Primavera do Leste, in Mato Grosso state, Central Brazil, including 265 children vaccinated through the National Immunization Program...
April 20, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29684319/lipid-accumulation-product-index-in-hiv-infected-patients-a-marker-of-cardiovascular-risk
#5
Milena Maria Moreira Guimarães, Dirceu Bartolomeu Greco, Allyson Nogueira Moreira, Nathalia Sernizon Guimarães, Cláudia Maria Vilas Freire, Bruna Guimarães Rolfs, Lucas José de Campos Machado
The lipid accumulation product (LAP) index is an emerging cardiovascular risk marker. We aimed to assess the accuracy of this index as a marker of cardiovascular risk in HIV-infected patients. A cross-sectional study of 133 HIV-infected patients on antiretroviral drugs and 20 non-infected controls was conducted at the outpatient clinic of a referral center of infectious and parasitic diseases. Evaluations included LAP index, homeostasis model assessment (HOMA) index, anthropometric measurements, blood pressure, glucose tolerance test, and cholesterol and triglyceride levels...
April 20, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29679545/the-impact-of-ocular-tuberculosis-on-vision-after-two-months-of-intensive-therapy
#6
Suzana Batista Vereza de Oliveira, Ângelo Ferreira Passos, David Jamil Hadad, Lorena Zbyszynski, Pedro Sousa de Almeida Júnior, Luiz Guilherme Schmidt Castellani, Reynaldo Dietze, Moisés Palaci
Tuberculosis (TB) is an infectious disease of global importance with major economic and social burden accounting for 25% of all avoidable deaths in developing countries. Extrapulmonary involvement may occur either in association with clinically apparent pulmonary tuberculosis or in isolation. This cross-sectional descriptive study aimed to evaluate the impact of ocular tuberculosis in visual acuity at baseline and after two months of intensive anti-tuberculous therapy. A sample of 133 pulmonary TB patients, seven disseminated TB, and three pleural TB patients was evaluated...
April 18, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29625021/hepatitis-c-viral-load-in-hcv-monoinfected-and-hcv-hiv-1-hcv-htlv-1-2-and-hcv-hiv-htlv-1-2-co-infected-patients-from-s%C3%A3-o-paulo-brazil
#7
Fabiana Aparecida Alves, Karoline Rodrigues Campos, Marcílio Figueiredo Lemos, Regina Célia Moreira, Adele Caterino-de-Araujo
Co-infections of hepatitis C virus (HCV) and either human immunodeficiency virus type 1 (HIV-1), human T-cell lymphotropic virus type 1 (HTLV-1) or type 2 (HTLV-2) have been described as having an impact on HCV viremia and subsequent disease progression. HCV load in serum samples from 622 patients (343 males, 279 females; median age 50.8 years) from São Paulo/southeast Brazil was analyzed using the Abbott Real Time HCV assay (Abbott Molecular Inc., IL, USA). Samples were obtained from HCV-monoinfected (n=548), HCV/HIV-1- (n=41), HCV/HTLV-1- (n=16), HCV/HTLV-2- (n=8), HCV/HIV/HTLV-1- (n=4), and HCV/HIV/HTLV-2-co-infected (n=5) patients, and results were compared among the groups and according to sex...
April 3, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29605537/furuncular-myiasis-due-to-cordylobia-anthropophaga-in-a-latin-american-resident
#8
LETTER
Beuy Joob, Viroj Wiwanitkit
No abstract text is available yet for this article.
March 29, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29601791/biofilm-production-by-clinical-isolates-of-pseudomonas-aeruginosa-and-structural-changes-in-lasr-protein-of-isolates-non-biofilm-producing
#9
Jailton Lobo da Costa Lima, Lilian Rodrigues Alves, Paula Regina Luna de Araújo Jacomé, João Pacífico Bezerra Neto, Maria Amélia Vieira Maciel, Marcia Maria Camargo de Morais
INTRODUCTION: Biofilm production is an important mechanism for the survival of Pseudomonas aeruginosa and its relationship with antimicrobial resistance represents a challenge for patient therapeutics. P. aeruginosa is an opportunistic pathogen frequently associated to nosocomial infections, especially in imunocompromised hosts. OBJECTIVES: Analyze the phenotypic biofilm production in P. aeruginosa isolates, describe clonal profiles, and analyze quorum sensing (QS) genes and the occurrence of mutations in the LasR protein of non-biofilm producing isolates...
March 27, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29601790/is-visceral-leishmaniasis-the-same-in-hiv-coinfected-adults
#10
Guilherme Alves de Lima Henn, Alberto Novaes Ramos Júnior, Jeová Keny Baima Colares, Lorena Pinho Mendes, João Gabriel Colares Silveira, Anderson Alberto Façanha Lima, Bárbara Pontes Aires, Mônica Cardoso Façanha
INTRODUCTION: Visceral Leishmaniasis (VL) is the most severe form of disease caused by the Leishmania donovani complex, with significant morbidity and mortality in developing countries. Worse outcomes occur among HIV-positive individuals coinfected with Leishmania. It is unclear, however, if there are significant differences on presentation between VL patients with or without HIV coinfection. METHODS: We reviewed medical records from adult patients with VL treated at a reference healthcare center in Fortaleza - Ceará, Brazil, from July 2010 to December 2013...
March 27, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29551334/risk-behavior-score-a-practical-approach-for-assessing-risk-among-msm-in-brazil
#11
Gustavo Machado Rocha, Lígia Regina Franco Sansigolo Kerr, Carl Kendall, Mark Drew Crosland Guimarães
HIV/AIDS epidemic is not well controlled, and multiple sexual behavior factors help explain high rates of HIV infection among men who have sex with men (MSM). This article proposes to exam the use of a potential risk behavior score for HIV infection, based on the type and number of sexual partners, and condom use, and their associated factors in a sample of MSM in Brazil. A cross sectional RDS (Respondent Driven Sampling) study was performed among 3738 MSM aged 18+ years old from ten Brazilian cities. The risk behavior score was composed by the number of male partners and anal condom use in the last year with steady, casual, and commercial partners...
March 15, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29551333/scrotal-swelling-in-a-farmworker-with-paracoccidioidomycosis
#12
Daniella Braz Parente, Guilherme Felix Louza, Leonardo Hoehl Carneiro, Gláucia Zanetti, Edson Marchiori
No abstract text is available yet for this article.
March 15, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29548778/detection-of-the-meca-gene-and-identification-of-staphylococcus-directly-from-blood-culture-bottles-by-multiplex-polymerase-chain-reaction
#13
Taisa Trevizani Rocchetti, Katheryne Benini Martins, Patricia Yoshida Faccioli Martins, Rogério Antonio de Oliveira, Alessandro Lia Mondelli, Carlos Magno Castelo Branco Fortaleza, Maria de Lourdes Ribeiro de Souza da Cunha
INTRODUCTION: Staphylococcus spp. - both S. aureus, including methicillin-resistant strains (MRSA) and coagulase negative staphylococci (CoNS) - are relevant agents of healthcare-associated infections. Therefore, the rapid recognition of MRSA and methicillin-resistant CoNS from blood stream infections is critically important for patient management. It is worth noting that inappropriate empiric therapy has been associated with higher in-hospital mortality. MATERIAL AND METHODS: In this study we evaluated a multiplex polymerase chain reaction (multiplex PCR) standardized to detect Staphylococcus spp...
March 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29545017/prevalence-of-guillain-barr%C3%A3-syndrome-among-zika-virus-infected-cases-a-systematic-review-and-meta-analysis
#14
REVIEW
Ludovica Barbi, Antonio Victor Campos Coelho, Luiz Cláudio Arraes de Alencar, Sergio Crovella
Zika virus (ZIKV) is an emergent flavivirus transmitted mainly through Aedes spp. mosquitoes that is posing challenge to healthcare services in countries experiencing an outbreak. Usually ZIKV infection is mild, but in some cases it has been reported to progress into neurological diseases such as microcephaly in infants and Guillain-Barré syndrome (GBS) in adults. GBS is a debilitating autoimmune disorder that affects peripheral nerves. Since ZIKV caused massive outbreaks in South America in the past few years, we aimed to systematically review the literature and perform a meta-analysis to estimate the prevalence of GBS among ZIKV-infected individuals...
March 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29500944/rocky-mountain-spotted-fever-brain-imaging-findings
#15
Bruna Melo Coelho Loureiro, Fabiano Reis, Grazielly de Fátima Pereira, Cristina Alba Lalli
No abstract text is available yet for this article.
March 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29500943/seronegativity-to-polio-viruses-among-previously-immunized-adult-candidates-to-solid-organ-transplantation
#16
Luciana Gomes Pedro Brandão, Pedro Emmanuel Alvarenga Americano do Brasil, Silas de Souza Oliveira, Edson Elias da Silva, Guilherme Santoro Lopes
In the current effort to eliminate polio from the world, it is important to recognize and vaccinate susceptible groups, especially immunocompromised patients living in countries where attenuated polio vaccine is still used. In this report, we describe the frequency of protective antibodies in a small sample of adult SOT candidates in whom previous vaccination could be ascertained. Patients included in this report were selected among the participants of an ongoing prospective study carried out at the Reference Center for Special Immunobiologicals of the Evandro Chagas National Institute of Infectious Diseases in Rio de Janeiro, Brazil...
March 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29499169/in-vitro-basal-t-cell-proliferation-among-asymptomatic-human-t-cell-leukemia-virus-type-1-patients-co-infected-with-hepatitis-c-and-or-human-immunodeficiency-virus-type-1
#17
Tatiane Assone, Tatiana M Kanashiro, Maira P M Baldassin, Arthur Paiva, Michel E Haziot, Jerusa Smid, Augusto Penalva de Oliveira, Luiz Augusto M Fonseca, Philip J Norris, Jorge Casseb
BACKGROUND: Infection with Human T cell Leukemia Virus type 1 can be associated with myelopathy/tropical spastic paraparesis (HAM/TSP) and other inflammatory diseases. Lymphocytes from about half of Human T cell Leukemia Virus type 1-infected subjects spontaneously proliferate in vitro, and how this phenomenon relates to symptomatic disease and viral burden is poorly understood. OBJECTIVE: To evaluate T-cell proliferation in vitro among patients co-infected with Human T cell Leukemia Virus type 1/Hepatitis C Virus/Human Immunodeficiency Virus type 1...
March 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29494796/seroprevalence-of-hepatitis-e-virus-in-chronic-hepatitis-c-in-brazil
#18
Guilherme Bricks, Jorge Figueiredo Senise, Henrique Pott Junior, Giuliano Grandi, Amanda Passarini, Débora Bellini Caldeira, Dimas Carnaúba Junior, Hamilton Antonio Bonilha de Moraes, Celso Franscisco Hernandes Granato, Adauto Castelo
BACKGROUND AND AIMS: Hepatitis E virus infection in patients with underlying chronic liver disease is associated with liver decompensation and increased lethality. The seroprevalence of hepatitis E virus in patients with chronic hepatitis C in Brazil is unknown. This study aims to estimate the seroprevalence of hepatitis E virus in patients with chronic hepatitis C and to describe associated risk factors. METHODS: A total of 618 patients chronically infected with hepatitis C virus from three reference centers of São Paulo, Brazil were included...
March 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29476708/non-polarized-cytokine-profile-of-a-long-term-non-progressor-hiv-infected-patient
#19
Ana Flávia Pina, Vanessa Terezinha Gubert de Matos, Camila Mareti Bonin, Márcia Maria Ferrairo Janini Dal Fabbro, Inês Aparecida Tozetti
The HIV-1 initial viral infection may present diverse clinical and laboratory course and lead to rapid, intermediate, or long-term progression. Among the group of non-progressors, the elite controllers are those who control the infection most effectively, in the absence of antiretroviral therapy (ART). In this paper, the TH1, TH2 and TH17 cytokines profiles are described, as well as clinical and laboratory aspects of an HIV-infected patient with undetectable viral load without antiretroviral therapy. Production of IL-6, IL-10, TNF-α, IFN-γ, and IL-17 was detected; in contrast IL-4 was identified...
March 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29462596/onabotulinumtoxin-type-a-improves-lower-urinary-tract-symptoms-and-quality-of-life-in-patients-with-human-t-cell-lymphotropic-virus-type-1-associated-overactive-bladder
#20
Jose Abraão Carneiro Neto, Silvane Braga Santos, Gloria Orge Orge, Davi Tanajura, Lucia Passos, Cassius José Oliveira, Rosana Andrade, Cláudio Galeno de Melo, Ubirajara Barroso, Edgar M Carvalho
AIM: To evaluate the efficacy of the onabotulinum toxin type A in the treatment of HTLV-1 associated overactive bladder and its impact on quality of life (QoL). METHODS: Case series with 10 patients with overactive bladder refractory to conservative treatment with anticholinergic or physical therapy. They received 200Ui of onabotulinumtoxin type A intravesically and were evaluated by overactive bladder symptoms score (OABSS) and King's Health Questionnaire. RESULTS: The mean (SD) of the age was 52+14...
March 2018: Brazilian Journal of Infectious Diseases
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