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Brazilian Journal of Infectious Diseases

D E Corzo-León, D Perales-Martínez, A Martin-Onraet, N Rivera-Martínez, A Camacho-Ortiz, H Villanueva-Lozano
BACKGROUND: Invasive fungal infections (IFIs) affect >1.5 million people per year. Nevertheless, IFIs are usually neglected and underdiagnosed. IFIs should be considered as a public-health problem and major actions should be taken to tackle them and their associated costs. Aim To report the incidence of IFIs in four Mexican hospitals, to describe the economic cost associated with IFIs therapy and the impact of adverse events such as acute kidney injury (AKI), liver damage (LD), and ICU stay...
November 2, 2018: Brazilian Journal of Infectious Diseases
Anca Drăgănescu, Oana Săndulescu, Dragoş Florea, Ovidiu Vlaicu, Anca Streinu-Cercel, Dan Oţelea, Victoria Aramă, Monica Luminiţa Luminos, Adrian Streinu-Cercel, Maria Niţescu, Alina Ivanciuc, Rodica Bacruban, Daniela Piţigoi
BACKGROUND: Influenza continues to drive seasonal morbidity, particularly in settings with low vaccine coverage. OBJECTIVES: To describe the influenza cases and viral circulation among hospitalized patients. METHODS: A prospective study based on active surveillance of inpatients with influenza-like illness (ILI) from a tertiary hospital in Bucharest, Romania, in the season 2016/17. RESULTS: A total of 446 patients were tested, with a balanced gender distribution...
October 31, 2018: Brazilian Journal of Infectious Diseases
Alexandre Malek, Sara Isabel Gomez-Villegas, Alejandro de la Hoz, Cima Nowbakht, Cesar A Arias
A 19-year-old patient who mistakenly received two doses of influenza vaccine 10 days before presentation, was admitted with malaise, weakness, and a purpuric non-blanching rash most prominent on the ankles followed by abdominal pain and hematochezia 72h later. The diagnosis of influenza vaccine-related Henoch-Schonlein vasculitis was made. This complication, although rare, is the most common vasculitis related to immunization.
October 30, 2018: Brazilian Journal of Infectious Diseases
Fernanda H Maruyama, Thais O Morgado, Richard C Pacheco, Luciano Nakazato, Valeria Dutra
No abstract text is available yet for this article.
October 30, 2018: Brazilian Journal of Infectious Diseases
Rolando Paternina-de la Ossa, Seila Israel do Prado, Maria Célia Cervi, Denissani Aparecida Ferrari Dos Santos Lima, Roberto Martinez, Fernando Bellissimo-Rodrigues
BACKGROUND: Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is spreading worldwide, but little is known about the epidemiology of this pathogen in Brazil. OBJECTIVE: To evaluate clinical and microbiological features of children with S. aureus infections admitted to a university hospital. METHODS: This was a cross-sectional study evaluating the potential risk factors for CA-MRSA, and a retrospective cohort evaluating in-hospital clinical outcomes...
October 30, 2018: Brazilian Journal of Infectious Diseases
Karla Maria Tamez-Torres, Pedro Torres-Gonzalez, Miguel E Cervera-Hernandez, Barbara Chavez-Mazari, Corazon de Jesus Barrientos-Flores, Miriam Bobadilla-Del Valle, Alfredo Ponce-de-Leon, Jose Sifuentes-Osornio
OBJECTIVES: To determine the factors associated with MTBC-positive blood culture. METHODS: Case-control study. Sociodemographic, clinical and laboratory data were collected from 2000 to 2015. RESULTS: We reviewed medical records of 533 patients with culture-proven TB, of whom 27.2% (145/533) had blood culture available. Patients with mycobacteremia presented more frequently with abdominal TB, body mass index (BMI) <18kg/m2 , and had lower hemoglobin and albumin levels...
October 30, 2018: Brazilian Journal of Infectious Diseases
Antonio V C Coelho, Ronald R de Moura, Rafael L Guimarães, Lucas A C Brandão, Sergio Crovella
OBJECTIVE: Antiretroviral therapy (ART) saved millions from HIV-1 infection and AIDS, but some patients do not experience adequate CD4+ T cells gain despite achieving viral suppression. The genetic component of this condition is not yet completely elucidated. OBJECTIVE: To identify predictive genetic markers of immune response to ART. METHODS: Case-control study. Out of 176 HIV-infected patients recruited in the city of Recife, Northeast Brazil, 67 patients with no immunologic response were the cases and the remaining 109 patients who responded were the controls...
October 27, 2018: Brazilian Journal of Infectious Diseases
Luciana Nascimento Pinto Canela, Maria Clara de Magalhães-Barbosa, Carlos Eduardo Raymundo, Sharon Carney, Marilda Mendonca Siqueira, Arnaldo Prata-Barbosa, Antonio José Ledo Alves da Cunha
OBJECTIVES: The role of viral co-detection in children with severe acute respiratory infection is not clear. We described the viral detection profile and its association with clinical characteristics in children admitted to the Pediatric Intensive Care Unit (PICU) during the 2009 influenza A(H1N1) pandemic. METHOD: Longitudinal observational retrospective study, with patients aged 0-18 years, admitted to 11 PICUs in Rio de Janeiro, with suspected H1N1 infection, from June to November, 2009...
October 23, 2018: Brazilian Journal of Infectious Diseases
Per Lundberg, Rune Andersson, Elizabeth S Machado, Tomaz Pinheiro da Costa, Cristina Barroso Hofer
BACKGROUND: Perinatally HIV-infected children are surviving into adulthood, and getting pregnant. There is a scarcity of information on health and pregnancy outcomes in these women. AIM: To evaluate characteristics related to HIV disease and pregnancy outcomes in perinatally infected women, and to compare these women with a group of youth with behaviorally acquired HIV-infection, at a reference hospital in Rio de Janeiro, Brazil. METHODS: A cohort study...
October 16, 2018: Brazilian Journal of Infectious Diseases
Igor Vasconcelos Rocha, Danilo Elias Xavier, Karoline Rissele Henrique de Almeida, Sibele Ribeiro de Oliveira, Nilma Cintra Leal
Acinetobacter baumannii is one of the most frequent Gram-negative opportunistic pathogens associated with hospital-acquired infection worldwide. We briefly describe A. baumannii isolates that were recovered from surrounding ICU bed surfaces, exhibiting multidrug resistance phenotype and belonging to some widely spread clonal complexes of clinical A. baumannii isolates.
September 25, 2018: Brazilian Journal of Infectious Diseases
Elisabete Andrade, Daniele Rocha, Marcela Fontana-Maurell, Elaine Costa, Marisa Ribeiro, Daniela Tupy de Godoy, Antonio G P Ferreira, Amilcar Tanuri, Patrícia Alvarez, Rodrigo Brindeiro
The Brazilian Public Health Service provides pegylated alfa-interferon (αPEG-IFN) free-of-charge to treat patients infected with HCV. The primary goal of HCV therapy is the long-term elimination of HCV from the blood to reduce the risk of HCV associated complications and death. Patient viremia affects treatment duration and response, thus influencing clinical decisions. We developed a high-throughput method to perform the quantification of RNA hepatitis C virus (HCV) virus load in plasma samples to monitor patients under treatment...
September 19, 2018: Brazilian Journal of Infectious Diseases
Rafael Oliveira Dos Reis, Margarida Neves Souza, Maria Cristina Piccoli Cecconi, Loeci Timm, Nilo Ikuta, Daniel Simon, Jonas Michel Wolf, Vagner Ricardo Lunge
INTRODUCTION: Nontyphoidal Salmonella serotypes are the main cause of human food-borne infection, including several hospitalization cases in the developing countries. AIM: To detect the main serotypes and to characterize the antibiotic resistance of human non-enteric and enteric nontyphoidal Salmonella from clinical isolates in Brazil. METHODS: Salmonella serotypes were identified by microbiological and molecular methods. Susceptibility testing to antibiotics was performed by agar disk diffusion...
September 18, 2018: Brazilian Journal of Infectious Diseases
Silvana Torres, Luciana Baria Perdiz, Eduardo Alexandrino Medeiros
OBJECTIVE: To determine the incidence of surgical site infection (SSI) in patients undergoing craniotomy and to compare 12-month and 3-month post-discharge surveillance periods in terms of their impact on the incidence of SSI in those patients. METHODS: This was a retrospective cohort study involving 173 adult patients submitted to "clean" craniotomy (without previous contamination of the surgical site), with or without implants, who were followed for six months at a university hospital in the city of São Paulo, Brazil...
September 12, 2018: Brazilian Journal of Infectious Diseases
Roberto Focaccia, Adriana Silva de Moraes, Maria Luiza Alessi Ribeiro, Karla Fabiana Begosso Sampaio da Fonseca Carbonari, Bruna de Souza Quevedo
No abstract text is available yet for this article.
August 16, 2018: Brazilian Journal of Infectious Diseases
Vinícius Victor Lorenzoni, Tanise Vendruscolo Dalmolin, Laísa Nunes Franco, Afonso Luis Barth, Rosmari Hörner
No abstract text is available yet for this article.
August 7, 2018: Brazilian Journal of Infectious Diseases
André Ricardo Araujo da Silva, Thais Carolina da Silva, Gabriel José Teixeira Bom, Raissa Maria Bastos Vasconcelos, Robinson Simões Junior
INTRODUCTION: Ventilator-associated pneumonia (VAP) is one of the most common healthcare-associated infections (HAI) in neonates admitted in neonatal intensive care units (NICUs). METHODS: We did a systematic review using PRISMA methodology to identify the main etiological agents in Brazilian NICUs. Eligible studies published without period restriction were identified in PUBMED, SCIELO, LILACS and DOAJ. Studies were included if they were conducted in neonates hospitalized at NICU...
July 2018: Brazilian Journal of Infectious Diseases
Diana Carolina Quintero-Gil, Alexander Uribe-Yepes, Marta Ospina, Francisco Javier Díaz, Marlen Martinez-Gutierrez
Dengue, the most prevalent arboviral disease worldwide, is caused by any of the four dengue virus (DENV) serotypes that co-circulate constantly in hyperendemic areas such as Medellin (Colombia), and these serotypes are transmitted by mosquitoes of the genus Aedes. In this study, we evaluated the replicative capacity of strains isolated in Medellin between 2003 and 2007 in C6/36 cells and in colonies of Aedes aegypti collected during 2010-2011 from high or low-incidence areas within the same city. The phylogenetic analysis grouped isolates according to the predominant genotypes found in the Americas, and the in vitro characterization showed differences in the morphological changes induced by the isolates of each of the isolated serotypes compared to the reference serotypes...
July 2018: Brazilian Journal of Infectious Diseases
Maria Rita Polo Gascón, Mirella de Almeida Mellão, Sandra Helena Mello, Rosangela Maria Negrão, Jorge Casseb, Augusto César Penalva de Oliveira
This study evaluated the impact of urinary incontinence (UI) on sexuality, body image, mood, and quality of life of patients with myyelopathy associated with HTLV-1/tropical spastic paraparesis (HAM/TSP). The sample consisted of 31 HAM/TSP outpatients, of both sexes, followed-up at the Emílio Ribas Infectology Institute. The following instruments were used: sociodemographic questionnaire, Hospital Anxiety and Depression Scale (HAD), Body Image Assessment Scale, Sexual Quotient Female (QS-F) and Male (QS-M) Versions, King's Health Questionnaire (KHQ), and Revised OSAME Motor Disability Score...
July 2018: Brazilian Journal of Infectious Diseases
Renata N Pires, Cassia F B Caurio, Gabriele Z Saldanha, Andreza F Martins, Alessandro C Pasqualotto
INTRODUCTION: Clostridium difficile is an important cause of diarrhoea, particularly in patients receiving antibiotic therapy. Recent studies have shown that a substantial proportion of C. difficile infections are acquired in the community, as a zoonotic disease. Brazil is a large exporter of meat and so far no study has evaluated meat contamination with C. difficile spores. METHODS: Here we analysed 80 retail meat products purchased from local supermarkets in a Brazilian metropolis (Porto Alegre, Southern Brazil)...
July 2018: Brazilian Journal of Infectious Diseases
Ana Carolina Bueno Silva, Leni Marcia Anchieta, Marianna Fischer de Paula Lopes, Roberta Maia de Castro Romanelli
BACKGROUND: Technologies and life support management have enhanced the survival of preterm infants. The immune system of newborns is immature, which contributes to the occurrence of healthcare-associated infections. The overlap of several conditions with neonatal sepsis and the difficulty of diagnosis and laboratory confirmation during this period result in a tendency to over-treat neonatal sepsis. The use of antimicrobial agents is a risk factor for multidrug-resistant bacterial infections...
July 2018: Brazilian Journal of Infectious Diseases
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