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Brazilian Journal of Infectious Diseases

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https://www.readbyqxmd.com/read/28759747/clonal-dissemination-of-vancomycin-resistant-enterococcus-faecium-st412-in-a-brazilian-region
#1
Geraldo da Silva Alves, Monalessa Fábia Pereira, Lais de Lima Bride, Ana Paula Ferreira Nunes, Ricardo Pinto Schuenck
Vancomycin-resistant Enterococcus faecium (VREfm) has emerged as an important global nosocomial pathogen, and this trend is associated with the spread of high-risk clones. Here, we determined the genetic and phenotypic features of 93 VREfm isolates that were obtained from patients in 13 hospitals in Vitória, Espírito Santo, Brazil, during 2012-2013. All the isolates were vancomycin-resistant and harbored the vanA gene. Only 6 (6.5%) of the VREfm isolates showed the ability to form biofilm. The 93 isolates analyzed belong to a single pulsed-field gel electrophoresis lineage and presented six subtypes...
July 28, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28759746/serum-markers-as-an-aid-in-the-diagnosis-of-pulmonary-fungal-infections-in-aids-patients
#2
Ana Isabela Passos, Rachel Polo Dertkigil, Marcelo de Carvalho Ramos, Ariane BussoLopes, Cibele Tararan, Erivan Olinda Ribeiro, Angélica Zaninelli Schreiber, Plinio Trabasso, Mariangela Ribeiro Resende, Maria Luiza Moretti
INTRODUCTION: The etiology of pulmonary infections in HIV patients is determined by several variables including geographic region and availability of antiretroviral therapy. MATERIALS AND METHODS: A cross-sectional prospective study was conducted from 2012 to 2016 to evaluate the occurrence of pulmonary fungal infection in HIV-patients hospitalized due to pulmonary infections. Patients' serums were tested for (1-3)-β-D-Glugan (BG), galactomannan, and lactate dehydrogenase (LDH)...
July 28, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28732190/comparison-of-the-acc-aha-and-framingham-algorithms-to-assess-cardiovascular-risk-in-hiv-infected-patients
#3
Lauro Ferreira da Silva Pinto Neto, Fernanda Rezende Dias, Flavia Feres Bressan, Carolina Rocio Oliveira Santos
The aim of this study was to compare the predictions of Framingham cardiovascular (CV) risk score (FRS) and the American College of Cardiology/American Heart Association (ACC/AHA) risk score in an HIV outpatient clinic in the city of Vitoria, Espirito Santo, Brazil. In a cross-sectional study 341 HIV infected patients over 40 years old consecutively recruited were interviewed. Cohen's kappa coefficient was used to assess agreement between the two algorithms. 61.3% were stratified as low risk by Framingham score, compared with 54% by ACC/AHA score (Spearman correlation 0...
July 18, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28711456/a-cross-sectional-study-assessing-the-pharyngeal-carriage-of-neisseria-meningitidis-in-subjects-aged-1-24-years-in-the-city-of-embu-das-artes-s%C3%A3-o-paulo-brazil
#4
Lily Yin Weckx, Rosana Fiorini Puccini, Antónia Machado, Maria Gisele Gonçalves, Suely Tuboi, Eliana de Barros, Raghavendra Devadiga, Eduardo Ortega-Barria, Romulo Colindres
Meningococcal carriage is a prerequisite for invasive infection. This cross-sectional study assessed the pharyngeal carriage prevalence in healthy subjects aged 1-24 years in Embu das Artes city, São Paulo, Brazil. Pharyngeal swabs were examined for the presence of Neisseria meningitidis. The isolates were tested for different serogroups using agglutination and polymerase chain reaction. A logistic regression model assessed any independent association between Neisseria meningitidis carriage and various risk factors...
July 13, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28711455/recommendations-for-outpatient-parenteral-antimicrobial-therapy-in-brazil
#5
REVIEW
Priscila R Oliveira, Vladimir C Carvalho, Sergio Cimerman, Ana Lucia Munhoz Lima
A panel of national experts was convened by the Brazilian Infectious Diseases Society in order to determine the recommendations for outpatient parenteral antimicrobial therapy (OPAT) in Brazil. The following aspects are covered in the document: organization of OPAT programs; patient evaluation and eligibility criteria, including clinical and sociocultural factors; diagnosis of eligibility; venous access and antimicrobial infusion devices; protocols for antimicrobial use and monitoring and cost-effectiveness...
July 13, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28704642/infections-after-shoulder-arthroplasty-are-correlated-with-higher-anesthetic-risk-score-a-case-control-study-in-brazil
#6
Leonardo Hideto Nagaya, Mauro José Costa Salles, Lucas Sadawo Chagas Takikawa, Marcelo Fregoneze, Pedro Doneux, Luciana Andrade da Silva, Guilherme do Val Sella, Alberto Naoki Miyazaki, Sergio Luiz Checchia
PURPOSES: Shoulder arthroplasty (SA) has been performed by many years for the treatment of several conditions, including osteoarthritis and proximal humeral fractures following trauma. Surgical site infection (SSI) following SA remains a challenge, contributing to increased morbidity and costs. Identification of risk factors may help implementing adequate strategies to prevent infection. We aimed to identify pre- and intra-operative risk factors associated with deep infections after SA...
July 10, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28692823/high-hiv-infection-prevalence-in-a-group-of-men-who-have-sex-with-men
#7
Raquel Maria Cardoso Torres, Marly Marques da Cruz, André Reynaldo Santos Périssé, Denise Ribeiro Franqueira Pires
Brazil is characterized by a concentrated AIDS epidemic, it has a prevalence of less than 1% in the general population. However, there are higher rates in specific populations, especially in men who have sex with men. The study's aim was to analyze the association between sociodemographic characteristics, sexual practices, sexual behaviors and the HIV infection in a group of men who have sex with men. Secondary data was collected between June 2014 and September 2015 in a research of cross-sectional design in the city of Rio de Janeiro, Brazil...
July 8, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28688628/will-mayaro-virus-be-responsible-for-the-next-outbreak-of-an-arthropod-borne-virus-in-brazil
#8
REVIEW
Danillo Lucas Alves Esposito, Benedito Antonio Lopes da Fonseca
Mayaro virus (MAYV) is an alphavirus from the Togaviridae family and is transmitted mainly by Hemagogus mosquitoes. This virus circulates in high-density tropical forests or rural areas of Central and South America causing a disease characterized by high-grade fever, maculopapular skin rash and marked arthralgia that, in some patients, can persist for long periods after infection and may be misinterpreted as chikungunya. Although only a few outbreaks involving this virus have been reported, in the last years the number of MAYV infections has increased in the central and northern regions of Brazil...
July 6, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28688627/human-parechovirus-sepsis-like-illness-and-pulmonary-infection
#9
LETTER
Luíne Rosele Renaud Vidal, Bárbara Cavalli, Sérgio Monteiro de Almeida, Sônia Mara Raboni, Meri Bordignon Nogueira
No abstract text is available yet for this article.
July 6, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28648813/rapid-spread-of-an-ongoing-outbreak-of-zika-virus-disease-in-pregnant-women-in-a-mexican-hospital
#10
Elvira Garza-González, Soraya Mendoza-Olazarán, Raúl R Campos, Ricardo Téllez-Marroquín, Donato Saldívar-Rodríguez, Juan A Soria-López, Abel Santos, Samantha Flores-Treviño, Adrián Camacho-Ortiz
In the first nine weeks of implementation of a Zika Virus Preparedness Plan in a Mexican Public Hospital, we cared for 221 pregnant women with any signal or symptom suggesting ZIKV infection and 99 (44.8%) patients were found to be positive for ZIKV. The median age of patients was 25.3 years (range 13-49). Symptoms in PCR-positive patients were rash (91.4%) followed by headache (53.1%), myalgia (46.9%), arthralgia (45.7%), pruritus (35.8%), retroocular pain (29.6%), conjunctivitis (21%), and fever (21%). The women's epidemiologic exposure history indicates local transmission and a community outbreak...
June 22, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28641091/increasing-rates-of-clostridium-difficile-infection-in-mexican-hospitals
#11
Laura Palau Dávila, Elvira Garza-González, Patricia Rodríguez-Zulueta, Rayo Morfín-Otero, Eduardo Rodríguez-Noriega, Diana Villar-Compte, Juan C Rodríguez-Aldama, Adrián Camacho-Ortiz
INTRODUCTION: The epidemiology of Clostridium difficile infection (CDI) has changed in the last two decades. There is a lack of information regarding incidence and severity of CDI, especially in the developing world. METHODS: This was a retrospective and observational study from four hospitals of three Mexican cities. Patients were diagnosed with CDI when presented with loose stools and had at least one of the following tests positive: toxins assay, real-time PCR, or an endoscopic image compatible with pseudomembranous colitis...
June 19, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28628760/tuberculosis-incidence-among-people-living-with-hiv-aids-with-virological-failure-of-antiretroviral-therapy-in-salvador-bahia-brazil
#12
Monaliza Cardozo Rebouças, Márcio Oliveira da Silva, Tatiana Haguihara, Carlos Brites, Eduardo Martins Netto
Antiretroviral therapy (ART) for HIV has led to increased survival of HIV-infected patients. However, tuberculosis (TB) remains the leading opportunistic infection and cause of death among people living with HIV/AIDS (PLWHA). TB has been shown to be a good predictor of virological failure among PLWHA. This study aimed to evaluate the incidence of TB and its consequences among individuals diagnosed with virological failure of HIV. This was a retrospective cohort study involving PLWHA being followed-up in an AIDS reference center in Salvador, Bahia, Brazil...
June 16, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28623676/unrecognized-pediatric-and-adult-family-members-of-children-with-acute-brucellosis
#13
Dilek Yılmaz Çiftdoğan, Selda Aslan
BACKGROUND AND AIM: Brucellosis is an infectious, contagious and zoonotic disease that occurs worldwide. The family members of an index case of brucellosis may be especially susceptible, due to sharing the same source of infection and similar risk factors for brucellosis. In this study, we propose to screen pediatric and adult family members of brucellosis index cases for detecting additional unrecognized infected family members. MATERIALS AND METHODS: 114 family members of 41 pediatric patients with brucellosis were evaluated...
June 14, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28623675/development-of-a-prototype-immunochromatographic-test-for-rapid-diagnosis-of-respiratory-adenovirus-infection
#14
Inarei Paulini, Joselma Siqueira-Silva, Luciana Thomaz, Leticia Rocha, Charlotte Harsi, Nancy Bellei, Celso Granato
Human adenoviruses comprise an important group of etiologic agents that are responsible for various diseases in adults and children, such as respiratory, ocular, gastroenteric, and urinary infections. In immunocompromised and organ-transplanted individuals, these agents can cause generalized infections. Rapid diagnostic methods for detecting these infectious agents are not widely available. The aim of this work was to produce monoclonal and polyclonal anti-adenovirus antibodies to be used in a rapid diagnostic test for respiratory infections...
June 14, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28609647/a-case-of-chronic-lacrimal-canaliculitis-revisiting-the-role-of-actinomyces-israelii
#15
LETTER
Srujana Mohanty, Subhrajyoti Sahu, Sucheta Parija, Ashok K Praharaj
No abstract text is available yet for this article.
June 10, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28606416/intrauterine-fetal-death-due-to-congenital-cytomegalovirus-cmv-infection
#16
Stefano Licci
No abstract text is available yet for this article.
June 9, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28606415/identification-of-hepatitis-b-virus-a1762t-g1764a-double-mutant-strain-in-patients-in-southern-brazil
#17
Adaliany Souza, Giórgia Marasca, Nélson Kretzmann-Filho, Aline Dall-Bello, Dimas Kliemann, Cristiane Tovo, Ana Veiga
Infection by hepatitis B virus (HBV) is a worldwide public health problem. Chronic HBV infection with high viral replication may lead to cirrhosis and/or hepatocellular carcinoma. Mutant HBV strains, such as the HBV A1762T/G1764A double mutant, have been associated with poor prognosis and higher risk of the patient for developing cirrhosis and/or hepatocellular carcinoma. This study analyzed the presence of the HBV A1762T/G1764A double mutant in patients with chronic HBV and its association with clinical parameters such as viral load, aminotransferases, and HBV antigens...
June 9, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28606414/high-prevalence-of-hepatitis-e-virus-antibodies-in-sao-paulo-southeastern-brazil-analysis-of-a-group-of-blood-donors-representative-of-the-general-population
#18
Ana Maria Passos-Castilho, Mônica Renata Reinaldo, Anne de Sena, Celso F H Granato
Brazil is a non-endemic country for hepatitis E virus (HEV) infection with seroprevalence from 1% to 4% in blood donors and the general population. However, data on seroprevalence of HEV in the country are still limited. This study evaluated the prevalence of past or present HEV infection in a group of blood donors representative of the general population of the city of Sao Paulo, Southeastern Brazil. Serum samples from 500 blood donors were tested from July to September 2014 by serological and molecular methods...
June 9, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28606413/leishmania-donovani-infection-activates-tlr-2-4-expressions-and-tgf-%C3%AE-mediated-apoptosis-in-renal-tissues
#19
Vinod Kumar, Neeraj Tiwari, Mallikarjun Rao Gedda, Rizwanul Haque, Rakesh K Singh
The present study was aimed to identify the underlying mechanisms of improper renal function in Leishmania donovani infection that causes VL. Mice (BALB/c) were infected with L. donovani and different parameters for proteinuria were assessed. The levels of superoxide anion (O2(-)), hydrogen peroxide (H2O2), lipid peroxidation (MDA), inflammatory cytokines, and toll-like receptor (TLR) 2 and 4 expression were found significantly elevated at 60th day in these animals and declined at 90th day post infection. However, TGF-β and caspase 3 activities were higher at 90th day in comparison to 60th day post infection...
June 9, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28602616/salivary-anti-pgl-1-igm-may-indicate-active-transmission-of-mycobacterium-leprae-among-young-people-under-16-years-of-age
#20
Alexandre Casimiro de Macedo, José Evandro Cunha, Juliana Navarro Ueda Yaochite, Clodis Maria Tavares, Aparecida Tiemi Nagao-Dias
Considering that the main route of Mycobacterium leprae transmission is the upper respiratory tract, detection of salivary antibodies can be a useful tool for diagnosing early infection. The study aimed to analyze salivary anti-PGL-1 IgA and IgM antibodies in 169 children aged 4-16 years old, who lived nearby or inside the house of multibacillary or paucibacillary leprosy patients in two endemic cities in Alagoas State - Brazil. Salivary anti-PGL-1 antibodies were quantified by modified ELISA method. The frequency of contact and clinical form of the index case were significantly associated with salivary antibodies levels...
June 8, 2017: Brazilian Journal of Infectious Diseases
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