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Brazilian Journal of Infectious Diseases

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https://www.readbyqxmd.com/read/30017854/schistosomal-liver-fibrosis-and-hepatocellular-carcinoma-case-series-of-patients-submitted-to-liver-transplantation
#1
Norma Arteiro Filgueira, Camilla Maria de Alencar Saraiva, Norma Thomé Jucá, Matheus Filgueira Bezerra, Claudio Moura Lacerda
Schistosomiasis affects approximately 207 million people in 76 countries. The association between hepatocellular carcinoma (HCC) and Schistosoma mansoni infection (SMI) has been investigated. Studies using animal models suggest that the parasite may accelerate the oncogenic process when combined with other factors, such as hepatitis C virus infection or exposure to a carcinogen. Herein, we report a case series of six HCC patients from Northeast Brazil, with negative serology for both hepatitis B and C virus, submitted to liver transplantation, whose explant showed evidence of schistosomal liver fibrosis (SLF)...
July 12, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29963991/drug-repositioning-a-new-alternative-in-infectious-diseases
#2
LETTER
Marissa Bolson Serafin, Rosmari Hörner
No abstract text is available yet for this article.
June 28, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29963990/tailoring-antimicrobials-in-febrile-neutropenia-using-faster-diagnostic-and-communication-tools-to-improve-treatment-in-the-era-of-extensively-resistant-pathogens
#3
Ingvar Ludwig Augusto de Souza, Milene Gonçalves Quiles, Bruno Cruz Boettger, Antonio Carlos Campos Pignatari, Paola Cappellano
No abstract text is available yet for this article.
June 28, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29936099/immediate-start-of-antiretroviral-why-not
#4
LETTER
Elaine Monteiro Matsuda, Luana Portes Ozório Coelho, Cintia Mayumi Ahagon, Ivana Barros Campos, Luís Fernando de Macedo Brígido
No abstract text is available yet for this article.
June 21, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29936098/an-exuberant-form-of-disseminated-histoplasmosis
#5
Débora Mânica Rockenbach, Lia Natalia Diehl Dallazem, Raíssa Londero Chemello, André Avelino Costa Beber
No abstract text is available yet for this article.
June 21, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29883585/low-variation-in-initial-cd4-cell-count-in-a-hiv-referral-center-in-salvador-brazil-from-2002-to-2015
#6
Marcela Fonseca Pereira, Estela Luz, Eduardo Martins Netto, Manoel Henrique Fonseca Barbosa, Carlos Brites
Early initiation of antiretroviral therapy increases the likelihood of effective immune restoration, quality of life, and greater life expectancy for HIV-infected individuals. We evaluated the evolution of mean CD4+ cells count at diagnosis of HIV/AIDS in Salvador, Brazil from 2002 to 2015. We identified HIV/AIDS patients older than 18 years with diagnosis of HIV infection from 2002 to 2015, who had their first laboratory evaluation at Complexo Hospitalar Prof. Edgard Santos, Federal University of Bahia. Initial mean CD4+ cells count and age, over time were evaluated...
June 6, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29879426/re-emergence-of-human-t-lymphotropic-viruses-in-west-africa
#7
REVIEW
Nneoma Confidence JeanStephanie Anyanwu, Elijah Ekah Ella, Aghogho Ohwofasa, Maryam Aminu
Human T-lymphotropic viruses (HTLV) are Deltaretroviruses that infect millions of individuals worldwide via the same transmission routes as HIV. With the aim of exposing the possible re-emergence of HTLV in West Africa since discovery, a systematic review was carried out, focusing on the distribution of the virus types and significance of frequent indeterminate reports, while highlighting the need for mandatory routine blood screening. Capturing relevant data from discovery till date, sources searched were Google Scholar, CrossRef, NCBI (PubMed), MEDLINE, Research Gate, Mendeley, abstracts of Conferences and Proceedings, organization websites and reference lists of selected papers...
June 5, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29879425/impact-of-a-h1n1-influenza-in-children-at-a-brazilian-university-hospital
#8
Gabriela Fontanella Biondo, João Carlos Santana, Patrícia M Lago, Jefferson Piva, Paulo Ricardo A Souza, Joana Genz Gaulke, Juliana M Sebben
BACKGROUND: A/H1N1 influenza is a viral disease that affects a significant part of the population mainly in winter, leading to increased number of medical consultations, hospitalizations and consequently care spending in emergency. METHODS: This is a case-series retrospective study, involving patients admitted to a tertiary hospital in southern Brazil in 2016 with a clinical diagnosis of acute respiratory infection of the influenza type and laboratory confirmation of influenza A/H1N1...
June 5, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29879424/trypanosoma-cruzi-analysis-of-two-different-strains-after-piplartine-treatment
#9
Gabriela Alves Licursi Vieira, Marco Túlio Alves da Silva, Luis Octávio Regasini, Fernando Cotinguiba, Helen Julie Laure, José César Rosa, Maysa Furlan, Regina Maria Barretto Cicarelli
The hemoflagellate protozoan, Trypanosoma cruzi, mainly transmitted by triatomine insects through blood transfusion or from mother-to-child, causes Chagas' disease. This is a serious parasitic disease that occurs in Latin America, with considerable social and economic impact. Nifurtimox and benznidazole, drugs indicated for treating infected persons, are effective in the acute phase, but poorly effective during the chronic phase. Therefore, it is extremely urgent to find innovative chemotherapeutic agents and/or effective vaccines...
June 5, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29842872/inability-to-work-due-to-chikungunya-virus-infection-impact-on-public-service-during-the-first-epidemic-in-the-state-of-cear%C3%A3-northeastern-brazil
#10
LETTER
Maria Luiza Almeida Bastos, Francileudo Santos de Abreu, Geraldo Bezerra da Silva Junior
No abstract text is available yet for this article.
May 26, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29806996/fatal-case-of-donor-derived-colistin-resistant-carbapenemase-producing-klebsiella-pneumoniae-transmission-in-cardiac-transplantation
#11
Lisia Miglioli Galvão, Anna Paula Romero de Oliveira, Aline Santos Ibanês, Jussimara Monteiro, Fernanda Inoue, Daniel Chagas Dantas, Flavio Sanchez, Daniel Wagner Santos, Cely Saad Abboud
Herein we report a fatal case of donor-derived transmission of XDR-resistant carbapenemase-producing Klebsiella pneumoniae (KPC-Kp) in cardiac transplantation. A 59-year-old male patient with non-obstructive hypertrophic cardiomyopathy underwent heart transplantation. On day 5 post-operation, blood cultures from the donor were positive for colistin-resistant carbapenemase-producing K. pneumoniae (ColR KPC-Kp) susceptible only to amikacin. Recipient blood cultures were also positive for ColR KPC-Kp with the same sensitivity profile as the donor isolate with an identical PFGE pattern...
May 26, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29787713/interferon-gamma-release-assay-performance-in-northeastern-brazil-influence-of-the-ifng-874-a-t-polymorphism
#12
Valdirene Leão Carneiro, Maria Teresita Bendicho, Rosalina Guedes Santos, Marilda Casela, Eduardo M Netto, Scarlet Torres Moraes Mota, Iza Cristina Araújo Pina, Roberto Meyer Nascimento, Songeli Menezes Freire, Theolis Barbosa
INTRODUCTION: Latent tuberculosis infection diagnosis based on the release of interferon-gamma in cultures of peripheral blood cells stimulated with Mycobacterium tuberculosis antigens has replaced the tuberculin skin test in many countries with low tuberculosis prevalence. The IFN-γ production can be influenced by genetic polymorphisms, of which the IFNG+874 (rs62559044) locus is the most studied. We investigated the possible influence of the IFNG+874 A/T polymorphism on interferon-gamma test performance...
May 19, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29782827/prevalence-and-risk-factors-of-mild-chronic-renal-failure-in-hiv-infected-patients-influence-of-female-gender-and-antiretroviral-therapy
#13
Marina Pontello Cristelli, Joan Carles Trullàs, Federico Cofán, Naira Rico, Christian Manzardo, Juan Ambrosioni, Josep Lluis Bedini, Asunción Moreno, Fritz Diekmann, Jose Maria Miro
BACKGROUND: In people living with HIV, much is known about chronic kidney disease, defined as a glomerular filtration rate under 60mL/min. However, there is scarce data about prevalence and risk factors for milder impairment (60-89mL/min). OBJECTIVE: The present study aims to assess the influence of sex, antiretroviral therapy, and classical risk factors on the occurrence of mild decreased renal function in a large Spanish cohort of HIV-infected patients. METHODS: Cross-sectional, single center study, including all adult HIV-1-infected patients under antiretroviral treatment with at least two serum creatinine measures during 2014, describing the occurrence of and the risk factors for mildly decreased renal function (eGFR by CKD-EPI creatinine equation of 60-89mL/min)...
May 18, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29752892/high-vertical-hiv-transmission-rate-in-the-midwest-region-of-brazil
#14
Vanessa Terezinha Gubert de Matos, Fabiani de Morais Batista, Naiara Valera Versage, Clarice Souza Pinto, Vanessa Marcon de Oliveira, Érica Freire de Vasconcelos-Pereira, Roberta Barbeta Dos Rios de Matos, Márcia Maria Ferrairo Janini Dal Fabbro, Ana Lúcia Lyrio de Oliveira
OBJECTIVES: To estimate vertical HIV transmission rate in a capital city of the Midwest region of Brazil and describe the factors related to transmission. METHODS: A descriptive epidemiological study based on the analysis of secondary data from the Notifiable Diseases Information System (SINAN). The analysis considered all HIV-infected pregnant women with delivery in Campo Grande-MS in the years 2007-2013 and their HIV-exposed infants. RESULTS: A total of 218 births of 176 HIV-infected pregnant women were identified during the study period, of which 187 infants were exposed and uninfected, 19 seroconverted, and 12 were still inconclusive in July 2015...
May 9, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29752891/effectiveness-and-tolerability-of-direct-acting-antivirals-for-chronic-hepatitis-c-patients-in-a-southern-state-of-brazil
#15
Vinicius Lins Ferreira, Helena Hiemisch Lobo Borba, Astrid Wiens, Maria Lucia Alves Pedroso, Vanessa Ferreira de Camargo Radunz, Cláudia Alexandra Pontes Ivantes, Aline Satie Oba Kuniyoshi, Roberto Pontarolo
BACKGROUND: This study aimed to evaluate the clinical effectiveness in terms of sustained virological response and tolerability of available second generation direct-acting antivirals in Brazilian patients. METHODS: This was a retrospective observational study conducted in six centers in Southern Brazil. The sample comprised adult patients who were chronically infected with hepatitis C virus, regardless of virus genotype, fibrosis stage, or prior treatment. Statistical analysis was performed to compare the effectiveness among the treatments, and also to uncover the factors influencing the achievement of sustained virological response...
May 9, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29684320/initial-evaluation-of-universal-immunization-with-a-single-dose-against-hepatitis-a-virus-in-central-brazil
#16
Wagner Izidoro de Brito, Eduardo Rodrigues Alves-Junior, Rode Martinho de Oliveira, Francisco José Dutra Souto
Vaccination against the hepatitis A virus (HAV) administered in two doses has been used effectively in universal child immunization programs in several countries. A single-dose vaccination was adopted in some low-income countries in an attempt to reduce costs without losing effectiveness. In 2014, single-dose universal vaccination was introduced in Brazil for children aged two years. Since such strategy is still not universally accepted, its efficacy should be compared to the two-dose strategy. To assess the humoral response after the single-dose HAV vaccination schedule, a cross-sectional study was conducted in Primavera do Leste, in Mato Grosso state, Central Brazil, including 265 children vaccinated through the National Immunization Program...
April 21, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29684319/lipid-accumulation-product-index-in-hiv-infected-patients-a-marker-of-cardiovascular-risk
#17
Milena Maria Moreira Guimarães, Dirceu Bartolomeu Greco, Allyson Nogueira Moreira, Nathalia Sernizon Guimarães, Cláudia Maria Vilas Freire, Bruna Guimarães Rolfs, Lucas José de Campos Machado
The lipid accumulation product (LAP) index is an emerging cardiovascular risk marker. We aimed to assess the accuracy of this index as a marker of cardiovascular risk in HIV-infected patients. A cross-sectional study of 133 HIV-infected patients on antiretroviral drugs and 20 non-infected controls was conducted at the outpatient clinic of a referral center of infectious and parasitic diseases. Evaluations included LAP index, homeostasis model assessment (HOMA) index, anthropometric measurements, blood pressure, glucose tolerance test, and cholesterol and triglyceride levels...
April 20, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29679545/the-impact-of-ocular-tuberculosis-on-vision-after-two-months-of-intensive-therapy
#18
Suzana Batista Vereza de Oliveira, Ângelo Ferreira Passos, David Jamil Hadad, Lorena Zbyszynski, Pedro Sousa de Almeida Júnior, Luiz Guilherme Schmidt Castellani, Reynaldo Dietze, Moisés Palaci
Tuberculosis is an infectious disease of global importance with major economic and social burden accounting for 25% of all avoidable deaths in developing countries. Extrapulmonary involvement may occur either in association with clinically apparent pulmonary tuberculosis or in isolation. This cross-sectional descriptive study aimed to evaluate the impact of ocular tuberculosis in visual acuity at baseline and after two months of intensive anti-tuberculous therapy. A sample of 133 pulmonary tuberculosis patients, seven disseminated tuberculosis, and three pleural tuberculosis patients was evaluated...
April 19, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29625021/hepatitis-c-viral-load-in-hcv-monoinfected-and-hcv-hiv-1-hcv-htlv-1-2-and-hcv-hiv-htlv-1-2-co-infected-patients-from-s%C3%A3-o-paulo-brazil
#19
Fabiana Aparecida Alves, Karoline Rodrigues Campos, Marcílio Figueiredo Lemos, Regina Célia Moreira, Adele Caterino-de-Araujo
Co-infections of hepatitis C virus (HCV) and either human immunodeficiency virus type 1 (HIV-1), human T-cell lymphotropic virus type 1 (HTLV-1) or type 2 (HTLV-2) have been described as having an impact on HCV viremia and subsequent disease progression. HCV load in serum samples from 622 patients (343 males, 279 females; median age 50.8 years) from São Paulo/southeast Brazil was analyzed using the Abbott Real Time HCV assay (Abbott Molecular Inc., IL, USA). Samples were obtained from HCV-monoinfected (n=548), HCV/HIV-1- (n=41), HCV/HTLV-1- (n=16), HCV/HTLV-2- (n=8), HCV/HIV/HTLV-1- (n=4), and HCV/HIV/HTLV-2-co-infected (n=5) patients, and results were compared among the groups and according to sex...
March 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29605537/furuncular-myiasis-due-to-cordylobia-anthropophaga-in-a-latin-american-resident
#20
LETTER
Beuy Joob, Viroj Wiwanitkit
No abstract text is available yet for this article.
March 2018: Brazilian Journal of Infectious Diseases
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