Bing Liang, Xiongbin Chen, Min Li, Lingling Zhang, Xia Yang, Liangqin Shi, Yanju Gong, Yuanyuan Gong, Huan Xu, Xiao Wu, Zhong Jin, Yanru Wang, Luwei Liu, Xiaohong Yi, Lushuang Xie, Hua Zhong, Chongyang Shen, Yong Wang, Lan Yang
CONTEXT: Liuwei Dihuang pill (LWDH) has been used to treat postmenopausal osteoporosis (PMOP). OBJECTIVE: To explore the effects and mechanisms of action of LWDH in PMOP. MATERIALS AND METHODS: Forty-eight female Sprague-Dawley rats were divided into four groups: sham-operated (SHAM), ovariectomized (OVX), LWDH high dose (LWDH-H, 1.6 g/kg/d) and LWDH low dose (LWDH-L, 0.8 g/kg/d); the doses were administered after ovariectomy via gavage for eight weeks...
December 2024: Pharmaceutical Biology