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Journal of Medicinal Food

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https://www.readbyqxmd.com/read/29328869/inflammatory-bowel-diseases-and-fermentable-oligosaccharides-disaccharides-monosaccharides-and-polyols-an-overview
#1
Sandra Maria Barbalho, Ricardo de Alvares Goulart, Ana Luíza de Carvalho Aranão, Pamela Grazielle Correa de Oliveira
Inflammatory bowel diseases (IBDs) are mainly represented by ulcerative colitis and Crohn's disease, and the increase in the incidence tends to follow the rapid industrialization and lifestyle of modern societies. FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides, and polyols) consist of molecules that are poorly absorbed in the small intestine and are fermented by bacteria in the colon leading to symptoms such as bloating, flatulence, diarrhea, and abdominal pain. Reduction of the ingestion of FODMAP could reduce the symptoms and improve the quality of life...
January 12, 2018: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29319408/efficacy-and-safety-of-tremella-fuciformis-in-individuals-with-subjective-cognitive-impairment-a-randomized-controlled-trial
#2
Soonhyun Ban, Suji L Lee, Hyeonseok S Jeong, Soo Mee Lim, Shinwon Park, Young Sun Hong, Jieun E Kim
The efficacy and safety of Tremella fuciformis (TF) as a nutritional supplement were assessed in individuals with subjective cognitive impairment (SCI). Seventy-five individuals with SCI were enrolled in an 8-week, randomized, double-blind, placebo-controlled trial of TF (600 mg/day, n = 30 or 1200 mg/day, n = 30) or placebo (n = 15). The primary outcome measure was changes in total scores of the subjective memory complaint questionnaire. The secondary outcome measures were changes in performance on short-term memory and executive functions, which were assessed using standardized cognitive tests...
January 10, 2018: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29319388/woohwangcheongsimwon-prevents-high-fat-diet-induced-memory-deficits-and-induces-sirt1-in-mice
#3
Hyunwoo Park, Mia Kim, Im-Joon Shin, Jonghee Park, Soo Yong Bang, Chunsik Yi, Myoung-Ae Kim, Jae-Hwan Lew, Joo Won Suh, Sungho Maeng
Woohwangcheongsimwon (WHC) is a mixture of herbal medicines that is widely prescribed in Korean traditional medicine. SIRT1 is known for its regulatory roles in energy metabolism, oxidative stress, and circadian rhythms. This study was designed to determine whether WHC can increase and mimic the biological reactions of SIRT1 activation. Ten-month-old male mice were divided into four groups: nontreated normal diet (ND), nontreated high-fat diet (HFD), WHC-treated ND, and WHC-treated HFD. Body weight and cognitive functions were evaluated after treatment...
January 10, 2018: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29315019/time-and-intervention-effects-of-daily-almond-intake-on-the-changes-of-lipid-profile-and-body-composition-among-free-living-healthy-adults
#4
Yanan Liu, Hyo-Jeong Hwang, Hyun-Sook Kim, Hyunjin Park
Favorable health benefits of almond have been shown in several previous studies. However, repeated measures, randomized, controlled trials to investigate the changes due to almond intake based on the time effects have not yet been reported. The current study was conducted to evaluate the effects of daily almond intake on changes in body composition and lipid profiles for 20 weeks with four measurements among healthy adults. Participants in the almond group showed favorable changes on blood lipid profiles, including levels of triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and non-high-density lipoprotein (non-HDL-C) after consuming 56 g of almond per day for 20 weeks compared with those at baseline...
January 9, 2018: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29315017/amylase-trypsin-inhibitors-in-wheat-and-other-cereals-as-potential-activators-of-the-effects-of-nonceliac-gluten-sensitivity
#5
Yolanda Reig-Otero, Jordi Mañes, Lara Manyes
Nonceliac gluten sensitivity (NCGS) is a gluten-related gastrointestinal disorder distinct from celiac disease (CD) and gluten allergy that is not easy to diagnose due to the lack of biomarkers. It is characterized by intestinal symptoms and extraintestinal manifestations with the consumption of gluten-containing foods. In contrast to CD, NCGS patients do not present a genetic predisposition or intestinal villi atrophy. Recent studies question the proinflammatory triggering activity of α-gliadin fraction contained in wheat, since it has been demonstrated that the amylase-trypsin inhibitors (ATIs) exert a strong activating effect on the innate immune response...
January 9, 2018: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29315003/anti-obesity-effect-of-allium-hookeri-leaf-extract-in-high-fat-diet-fed-mice
#6
Seyeon Park, Kihoon No, Joomin Lee
Allium hookeri has been widely cultivated and used as a vegetable and medicine in Asia, but its anti-obesity effects have not been previously reported. In this study, the effects of a leaf extract of A. hookeri on obesity were investigated by administering a high-fat diet (HFD) to mice. Male Institute of Cancer Research mice (n = 32; 5 weeks old) were randomly divided into four groups: normal-diet group, HFD group, HFD containing 200 mg/kg/day A. hookeri leaf extract (HFD-A1), and HFD containing 400 mg/kg/day A...
January 9, 2018: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29298102/deer-bone-extract-supplementation-for-mild-to-moderate-knee-osteoarthritis-symptoms-a-randomized-double-blind-placebo-controlled-trial
#7
Dongseok Shin, Eun Ae Kim, Yoon Young Kim, Min Seo Kim, Jong Hoon Kim, Chang Won Ahn, Soo-Hyun Park, Ki Won Lee, Jae Hwa Kim, Ji Yeon Kim
In this randomized, double-blind, placebo-controlled study, we evaluated the efficacy of deer bone extract (DBE) in participants with knee osteoarthritis (OA). We enrolled 50 participants aged 50-70 years, having knee OA with a Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score ≥5.0. The participants were assigned to the placebo or DBE group (550 mg/day) for 12 weeks. The outcome measures were as follows: pain score on the visual analog scale (VAS); WOMAC score; and blood and urine biomarkers...
January 3, 2018: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29271701/red-ginseng-oil-inhibits-tpa-induced-transformation-of-skin-epidermal-jb6-cells
#8
Van-Long Truong, Ah-Ng Tony Kong, Woo-Sik Jeong
Red ginseng oil (RGO) has been shown to possess anti-inflammatory and hepatoprotective activity. In this study, we evaluated the inhibitory effect of RGO on 12-O-tetradecanoylphorbol-13-acetate (TPA)-stimulated neoplastic transformation of JB6 P+ cells. RGO pretreatment abolished the transformation of JB6 P+ cells challenged by TPA. RGO suppressed the transactivation of activator protein-1 (AP-1) and nuclear factor kappa B (NF-κB) transcription factors as well as protein levels of cyclooxygenase-2, cyclin D1, cyclin E, and Bcl-2 in the TPA-treated cells...
December 22, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29271694/beneficial-effects-of-kimchi-a-korean-fermented-vegetable-food-on-pathophysiological-factors-related-to-atherosclerosis
#9
Hyun Ju Kim, Jeong Sook Noh, Yeong Ok Song
Atherosclerosis is a progressive disease that is characterized by accumulation of lipids and fibrous elements in large arteries. Its etiology is involved with pathophysiological factors such as lipoprotein oxidation, inflammation, and dyslipidemia. Kimchi is a Korean fermented vegetable side dish made with vegetables and kimchi condiments. To date, numerous in vitro, in vivo, and human studies have cited the health benefits of kimchi. 3-(4'-Hydroxyl-3',5'-dimethoxyphenyl)propionic acid is one of the active compounds of kimchi, and its antioxidant and anti-atherosclerosclerotic effects have been reported...
December 22, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29261010/effect-of-chlorogenic-acid-administration-on-glycemic-control-insulin-secretion-and-insulin-sensitivity-in-patients-with-impaired-glucose-tolerance
#10
Laura Y Zuñiga, Martha C Aceves-de Aceves-de la Mora, Manuel González-Ortiz, Julia L Ramos-Núñez, Esperanza Martínez-Abundis
Chlorogenic acid has been described as a novel polyphenol with metabolic effects on glucose homeostasis. The aim of this study was to evaluate the effect of chlorogenic acid administration on glycemic control, insulin secretion, and insulin sensitivity in patients with impaired glucose tolerance (IGT). A randomized, double-blind, placebo-controlled clinical trial was performed in 30 patients with IGT; 15 patients randomly assigned to oral chlorogenic acid received 400 mg three times per day for 12 weeks, and the other 15 patients received placebo in the same way...
December 20, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29261008/the-medicinal-mushroom-grifola-gargal-ameliorates-allergic-bronchial-asthma
#11
Etsuko Harada, Corina N D'Alessandro-Gabazza, Masaaki Toda, Toshihiro Morizono, Toshiaki Totoki, Taro Yasuma, Kota Nishihama, Tetsu Kobayashi, Toshimitsu Sumiya, Hirokazu Kawagishi, Esteban C Gabazza
Grifola gargal Singer, a medicinal mushroom, has been found to be effective for the prevention and treatment of various chronic inflammatory diseases. However, the effects of G. gargal on allergic diseases are unknown. The present study investigated the effect of G. gargal extract on allergic bronchial asthma. Asthma was induced in mice by ovalbumin sensitization and inhalation. The grade of asthma was compared between mice fed with chow containing G. gargal extract and mice given standard chow. The human mast cell and eosinophilic cell lines were used for in vitro studies...
December 20, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29261006/feeding-obese-diabetic-mice-a-genistein-diet-induces-thermogenic-and-metabolic-change
#12
Schuyler Rockwood, Tom L Broderick, Layla Al-Nakkash
Obesity is associated with elevated plasma levels of glucocorticoids and reduced levels of thyroid hormones, both known to effect food intake and energy expenditure. Furthermore, tissue specific glucocorticoid metabolism is altered in obesity, increasing insulin resistance and cardiometabolic risk. The goal of this study was to examine whether these metabolic disturbances can be prevented with the isoflavone genistein in the ob/ob mouse, a model that resembles the phenotype in human obesity. Male ob/ob mice, aged 5 weeks, were fed either a genistein-rich diet (600 mg/kg) or a genistein-free diet for 4 weeks...
December 20, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29227176/metabolomics-approach-in-the-study-of-the-well-defined-polyherbal-preparation-zyflamend
#13
Eric D Tague, Allen K Bourdon, Amber MacDonald, Maggie S Lookadoo, Edward D Kim, Wesley M White, Paul D Terry, Shawn R Campagna, Brynn H Voy, Jay Whelan
Zyflamend is a highly controlled blend of 10 herbal extracts that synergistically impact multiple cell signaling pathways with anticancer and anti-inflammatory properties. More recently, its effects were shown to also modify cellular energetics, for example, activation of fatty acid oxidation and inhibition of lipogenesis. However, its general metabolic effects in vivo have yet to be explored. The objective of this study was to characterize the tissue specific metabolomes in response to supplementation of Zyflamend in mice, with a comparison of equivalent metabolomics data generated in plasma from humans supplemented with Zyflamend...
December 11, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29216438/antiulcerative-activity-of-milk-proteins-hydrolysates
#14
Wilman Carrillo, Karin Maia Monteiro, Daniel Martínez-Maqueda, Mercedes Ramos, Isidra Recio, João Ernesto de Carvalho
Several studies have shown the protective effect of dairy products, especially α-lactalbumin and derived hydrolysates, against induced gastric ulcerative lesions. The mucus strengthening represents an important mechanism in the defense of gastrointestinal mucosa. Previously, a hydrolysate from casein (CNH) and a hydrolysate from whey protein concentrate rich in β-lactoglobulin (WPH) demonstrated a stimulatory activity on mucus production in intestinal goblet cells. The aim of this work was to evaluate the possible antiulcerative activity of these two hydrolysates in an ethanol-induced ulcer model in rats...
December 7, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29215298/echinacea-purpurea-protects-against-restraint-stress-induced-immunosuppression-in-balb-c-mice
#15
Seonyoung Park, Mak-Soon Lee, Sunyoon Jung, Seohyun Lee, Oran Kwon, Matthias Heinrich Kreuter, Tania Perrinjaquet-Moccetti, Bokkee Min, Seong Ho Yun, Yangha Kim
Echinacea purpurea has been widely used for the prevention and treatment of upper respiratory tract infections and the common cold. The restraint stress has been reported to suppress a broad spectrum of immune functions. The aim of this study was to investigate the protective effects of the pressed juice of E. purpurea (L.) Moench (EFLA®894; Echinacea) against restraint stress-induced immunosuppression in BALB/c mice. Echinacea significantly normalized the restraint stress-induced reduction in splenocyte proliferation and splenic natural killer (NK) cell activity (P < ...
December 7, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29172966/antiquorum-sensing-activity-of-seed-oils-from-oleaginous-plants-and-protective-effect-during-challenge-with-chromobacterium-violaceum
#16
Macrina Pérez-López, Rodolfo García-Contreras, Marcos Soto-Hernández, José Salud Rodríguez-Zavala, Mariano Martínez-Vázquez, Francisco Javier Prado-Galbarro, Israel Castillo-Juárez
Seed oils from oleaginous plants are rich in fatty acids (FAs) that play important roles in the health of the consumers. Recent studies indicate that FA also can play an important role in communication and regulation of virulence in bacteria. Nevertheless, evidence demonstrating protection against bacterial infections mediated by their quorum sensing inhibition (QSI) activity is scarce. In this study, sunflower, chia, and amaranth oils, were assayed for their QSI capacity by inhibiting violacein production and alkaline exoprotease activity of Chromobacterium violaceum...
November 27, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29172901/correction-to-j-med-food-2017-20-1113-1120-doi-10-1089-jmf-2017-3951
#17
(no author information available yet)
No abstract text is available yet for this article.
November 27, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29161525/sea-cucumber-lipid-soluble-extra-fraction-prevents-ovalbumin-induced-allergic-airway-inflammation
#18
Da-In Lee, Shin Ae Kang, Anisuzzaman Md, U-Cheol Jeong, Feng Jin, Seok-Joong Kang, Jeong-Yeol Lee, Hak Sun Yu
In a previous study, our research group demonstrated that sea cucumber (Apostichopus japonicus) extracts ameliorated allergic airway inflammation through CD4(+)CD25(+)Foxp3(+) T (regulatory T; Treg) cell activation and recruitment to the lung. In this study, we aimed to determine which components of sea cucumber contribute to the amelioration of airway inflammation. We used n-hexane fractionation to separate sea cucumber into three phases (n-hexane, alcohol, and solid) and evaluated the ability of each phase to elevate Il10 expression in splenocytes and ameliorate symptoms in mice with ovalbumin (OVA)/alum-induced asthma...
November 21, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29131698/the-anti-inflammatory-and-antioxidant-effects-of-salvia-officinalis-on-lipopolysaccharide-induced-inflammation-in-rats
#19
Umut Kerem Kolac, Mehmet Cengiz Ustuner, Neslihan Tekin, Derya Ustuner, Emine Colak, Emre Entok
Salvia officinalis, which has a high phenolic acid and flavonoid content, is a powerful antioxidant and anti-inflammatory herb. Inflammation plays an important role in the pathophysiology of many diseases and could cause damage by means of oxidative stress. The aim of this study was to investigate the anti-inflammatory and antioxidant activity of S. officinalis formed lipopolysaccharide (LPS)-induced experimental inflammation model. Four- to five-month-old 42 female Wistar albino rats were divided into six groups...
November 13, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29125913/standardized-kaempferia-parviflora-extract-enhances-exercise-performance-through-activation-of-mitochondrial-biogenesis
#20
Mi-Bo Kim, Taeyoon Kim, Changhee Kim, Jae-Kwan Hwang
Exercise enhances mitochondrial biogenesis in skeletal muscle. Increased mitochondrial function and content can contribute to the improvement in skeletal muscle function and the benefits of exercise by increasing the response to energy demands. The effect of standardized Kaempferia parviflora extract (KPE) on exercise performance was accessed in L6 myotubes and C57BL/6J mice. KPE significantly activated peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) and increased mitochondrial density in L6 myotubes...
November 10, 2017: Journal of Medicinal Food
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