journal
MENU ▼
Read by QxMD icon Read
search

Journal of Medicinal Food

journal
https://www.readbyqxmd.com/read/29131706/alzheimer-s-disease-current-status-and-future-directions
#1
Deepshikha Bhardwaj, Connie Mitra, Chandrakala Aluganti Narasimhulu, Aladdin Riad, Mitsushita Doomra, Sampath Parthasarathy
Alzheimer's disease (AD) is an age-related neurodegenerative disorder of the brain. The presence of amyloid-beta (Aβ) plaques, neurofibrillary tangles (NFTs), loss of neurons, synapses, and altered sensory perceptions, including memory loss, delineate AD. However, the cause of AD is not clearly known. Several genetic and nongenetic factors have been implicated in the disease. Of the genes, the ɛ4 allele of apolipoprotein E is the largest known genetic risk factor of AD. This review article focuses on the various genetic and other predisposing factors that account for AD, pathophysiology of the disease, and the mechanisms by which Aβ plaques and NFTs are formed and could affect AD brain...
November 13, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29131698/the-anti-inflammatory-and-antioxidant-effects-of-salvia-officinalis-on-lipopolysaccharide-induced-inflammation-in-rats
#2
Umut Kerem Kolac, Mehmet Cengiz Ustuner, Neslihan Tekin, Derya Ustuner, Emine Colak, Emre Entok
Salvia officinalis, which has a high phenolic acid and flavonoid content, is a powerful antioxidant and anti-inflammatory herb. Inflammation plays an important role in the pathophysiology of many diseases and could cause damage by means of oxidative stress. The aim of this study was to investigate the anti-inflammatory and antioxidant activity of S. officinalis formed lipopolysaccharide (LPS)-induced experimental inflammation model. Four- to five-month-old 42 female Wistar albino rats were divided into six groups...
November 13, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29125913/standardized-kaempferia-parviflora-extract-enhances-exercise-performance-through-activation-of-mitochondrial-biogenesis
#3
Mi-Bo Kim, Taeyoon Kim, Changhee Kim, Jae-Kwan Hwang
Exercise enhances mitochondrial biogenesis in skeletal muscle. Increased mitochondrial function and content can contribute to the improvement in skeletal muscle function and the benefits of exercise by increasing the response to energy demands. The effect of standardized Kaempferia parviflora extract (KPE) on exercise performance was accessed in L6 myotubes and C57BL/6J mice. KPE significantly activated peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) and increased mitochondrial density in L6 myotubes...
November 10, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29116873/the-effect-of-experimental-supplementation-with-the-klamath-algae-extract-klamin-on-attention-deficit-hyperactivity-disorder
#4
Maurizio Cremonte, Davide Sisti, Ilaria Maraucci, Simona Giribone, Evelin Colombo, Marco Bruno Luigi Rocchi, Stefano Scoglio
Attention-deficit/hyperactivity disorder (ADHD) is a chronic neurobiological condition with onset in childhood. The disorder is characterized by inattention, impulsivity, and/or motor hyperactivity, which often affect the development and social integration of affected subjects. Phenylethylamine (PEA), naturally contained in the Klamath Lake microalgae and concentrated in the Klamin(®) extract, is an endogenous molecule with a general neuromodulatory activity. It functions as an activator for the neurotransmission of dopamine and other catecholamines, and very low concentrations of PEA may be associated with specific psychological disorders such as ADHD...
November 8, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29099642/oleuropein-is-responsible-for-the-major-anti-inflammatory-effects-of-olive-leaf-extract
#5
Khaled Qabaha, Fuad Al-Rimawi, Ahmad Qasem, Saleh A Naser
Olive leaves are rich in polyphenolic compounds that are known to have antioxidant, antimicrobial, and anti-inflammatory activities. Therefore, olive leaf extract (OLE) is considered as a natural supplement. In this study we evaluated the antibacterial and the anti-inflammatory effect of OLE and its individual phenolic components in vitro. Polymorphonuclear cells (PMNCs) were isolated from the whole blood using Histopaque solution and cultured in RPMI-enriched medium. Tumor necrosis factor α (TNFα) level was determined by ELISA after 24 h of lipopolysaccharide stimulation...
November 3, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29091526/hericium-erinaceus-extract-reduces-anxiety-and-depressive-behaviors-by-promoting-hippocampal-neurogenesis-in-the-adult-mouse-brain
#6
Sun Ryu, Hyoun Geun Kim, Joo Youn Kim, Seong Yun Kim, Kyung-Ok Cho
Versatile biological activities of Hericium erinaceus (HE) have been reported in many brain diseases. However, roles of HE in major psychiatric disorders such as depression and anxiety remain to be investigated. Therefore, we evaluated whether HE could reduce anxiety and depressive behaviors in the adult mouse and its underlying mechanisms. Male C57BL/6 mice were administered HE (20 or 60 mg/kg, p.o.) or saline once a day for 4 weeks. Open field and tail suspension tests were performed 30 min after the last administration of HE, followed by forced swim test 2 days later...
November 1, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29091513/apple-cider-vinegar-attenuates-oxidative-stress-and-reduces-the-risk-of-obesity-in-high-fat-fed-male-wistar-rats
#7
Ben Hmad Halima, Gara Sonia, Khlifi Sarra, Ben Jemaa Houda, Ben Slama Fethi, Aouidet Abdallah
Metabolic syndrome is a serious consequence of obesity characterized by increased cardiovascular risk factors such as hypertension, dyslipidemia, and glucose intolerance. While diets enriched with natural antioxidants showed beneficial effects on oxidative stress, blood pressure, and serum lipid composition, diet supplementation with synthetic antioxidants showed contradictive results. Thus, we tested, in this study, whether a daily dosage of Apple Cider Vinegar (ACV) would affect cardiovascular risk factor associated with obesity in high-fat diet (HFD)-induced hyperlipidemic Wistar rats...
November 1, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29090980/dolichos-lablab-protects-against-nonalcoholic-fatty-liver-disease-in-mice-fed-high-fat-diets
#8
A-Rang Im, Yun Hee Kim, Young Hwa Kim, Won-Kyung Yang, Seung Hyung Kim, Kwang Hoon Song
Hyacinth bean, Dolichos lablab or Lablab purpureus, has been used for centuries in India and China as an edible pod and animal forage, as well as to treat diarrhea and other gastrointestinal disease in traditional Korean medicine. Recently, we have demonstrated that D. lablab extract (DLL-Ex) prevented free fatty acid-induced lipid accumulation in an in vitro cellular nonalcoholic fatty liver disease (NAFLD) model. In this study, we, thus, aimed at clarifying the hepatoprotective effects of DLL-Ex in a high-fat diet-induced in vivo animal NAFLD model, as well as at elucidating underlying mechanisms of identified effects...
November 1, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29072974/the-occurrence-of-antibodies-against-gluten-in-children-with-autism-spectrum-disorders-does-not-correlate-with-serological-markers-of-impaired-intestinal-permeability
#9
Jan Józefczuk, Ewa Konopka, Joanna Beata Bierła, Ilona Trojanowska, Agnieszka Sowińska, Rafał Czarnecki, Lucjan Sobol, Paweł Józefczuk, Weronika Surdy, Bożena Cukrowska
There is evidence that children with autism spectrum disorders (ASDs) display an increased immune reactivity against gluten, which is supposed to be the effect of intestinal barrier abnormalities. The aim of study was to evaluate the relation of antibody induced by gluten to zonulin and intestinal fatty acid binding proteins (I-FABP), that is, serological markers of an impaired gut barrier. The study included 77 patients with ASDs. Zonulin, I-FABP, celiac-specific antibodies, anti-gliadin antibodies (AGA), and antibodies against neural transglutaminase 6 (TG6) of immunoglobulin (Ig) A and IgG classes were detected in sera...
October 26, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29072970/dipteryx-alata-vogel-may-improve-lipid-profile-and-atherogenic-indices-in-wistar-rats-dipteryx-alata-and-atherogenic-indices
#10
Adriana Maria Ragassi Fiorini, Sandra Maria Barbalho, Élen Landgraf Guiguer, Marie Oshiiwa, Claudemir Gregório Mendes, Rogério Lopes Vieites, Agnaldo Bruno Chies, Priscilla Bianca de Oliveira, Maricelma da Silva Soares de Souza, Claudia Cristina T Nicolau
Worldwide prevalence of noncommunicable chronic degenerative diseases is among the main causes of death worldwide. The consumption of some foods such as nuts and seeds may be beneficial in preventing these diseases. Dipteryx alata Vogel (DA), known popularly as Baru, belongs to the family Fabaceae and is a native fruit tree from the Brazilian savanna. The purpose of this study was to evaluate the use of seeds of DA on the metabolic and oxidative profile of Wistar rats. Animals were divided randomly into four groups (n = 10): G1 (control group), and G2 (treated with DA 20%), G3 (treated with DA 30%), and G4 (treated with DA 40%)...
October 26, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29068758/effects-of-biotin-supplementation-during-the-first-week-postweaning-increases-pancreatic-islet-area-beta-cell-proportion-islets-number-and-beta-cell-proliferation
#11
Wilma Tixi-Verdugo, Juan Contreras-Ramos, Gloria Sicilia-Argumedo, Michael S German, Cristina Fernandez-Mejia
During maturation, pancreatic islets achieve their full capacity to secrete insulin in response to glucose, undergo morphological changes in which alpha-cells decrease and beta-cell mass increases, and they acquire the normal alpha- and beta-cell proportion changes that are important for islet functions later in life. In rodents, the first week of postweaning is critical for islet maturation. Multiple studies have documented the detrimental effects of several conditions on pancreatic maturation; however, few studies have addressed the use of pharmacological agents to enhance islet maturation...
October 25, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29064307/metabolomic-analysis-and-antioxidant-effect-of-amla-emblica-officinalis-extract-in-preventing-oxidative-stress-induced-red-cell-damage-and-plasma-protein-alterations-an-in-vitro-study
#12
Rajaa Muthu Packirisamy, Zachariah Bobby, Sankar Panneerselvam, Smitha Mariam Koshy, Sajini Elizabeth Jacob
Amla (Emblica officinalis) has antidiabetic, hypolipidemic, anti-inflammatory, and antioxidant properties, but its effect on free radical induced red cell damage and membrane and plasma protein alterations has not been adequately addressed. The aim of the present study was to evaluate the antioxidant property of amla against oxidative stress induced red cell damage and plasma protein alterations. Red blood cells (RBCs) were preincubated with different concentrations of amla extract (50, 100, 150, and 200 μg/mL) and then treated with physiological (5 mM) and pathological (50 mM) concentrations of glucose for 24 h...
October 24, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29035613/quercetin-induced-amp-activated-protein-kinase-activation-attenuates-vasoconstriction-through-lkb1-ampk-signaling-pathway
#13
Seul Gi Kim, Jae-Ryong Kim, Hyoung Chul Choi
The vascular tone plays an important role in blood pressure and flow. It is influenced by the contraction of vascular smooth muscle cells (VSMCs), which in turn is regulated by the balance between the myosin light chain kinase (MLCK) and the phosphorylated myosin light chain (p-MLC). Quercetin is a common flavonoid which is found in many fruits and red wine. Although quercetin has been widely reported to be involved in cell proliferation, migration, and apoptosis in VSMCs, it has not yet been demonstrated whether quercetin is related to vasocontraction, a function regulated by the AMP-activated protein kinase (AMPK) signaling pathway...
October 16, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29023178/effect-of-calcium-derived-from-lithothamnion-sp-on-markers-of-calcium-metabolism-in-premenopausal-women
#14
John L Zenk, Joy L Frestedt, Michael A Kuskowski
A double-blind crossover pilot trial tested the hypothesis that botanically derived calcium could demonstrate greater influence over calcium metabolism markers compared with a nonplant-derived calcium carbonate supplement or placebo. Twelve fasting female subjects received a single oral dose of Aquamin F™ (derived from the marine algal Lithothamnion sp.), or calcium carbonate, or placebo. Blood and urine samples were collected at baseline and over 12 h to evaluate ionized and total calcium and parathyroid hormone (PTH)...
October 12, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29022834/phenolic-protein-interactions-effects-on-food-properties-and-health-benefits
#15
Nydia E Buitimea-Cantúa, Janet A Gutiérrez-Uribe, Sergio O Serna-Saldívar
Phenolic-protein interactions (PPI), which naturally occur in most food systems, are being intentionally designed to enhance functional performance of phenolic compounds (PC). PPI have been primarily associated with changes related to sensorial, nutritional, and nutraceutical features of foods. Furthermore, these interactions affect properties such as astringency, protein digestibility, absorption, and bioavailability of antioxidants. Therefore, new product development should pay attention to these interactions and not only on the concentration of PC...
October 12, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/28981384/the-effects-of-a-korean-ginseng-ginst15-on-hypo-pituitary-adrenal-and-oxidative-activity-induced-by-intense-work-stress
#16
Shawn D Flanagan, William H DuPont, Lydia K Caldwell, Vincent H Hardesty, Emily C Barnhart, Matthew K Beeler, Emily M Post, Jeff S Volek, William J Kraemer
The effect of GINST15, an enzyme fermented ginseng supplement, on hormonal and inflammatory responses to physical stress in humans is unknown. The purpose of this investigation was to examine the constitutive and stress-induced effects of GINST15 supplement on hypo-pituitary-adrenal (HPA) and antioxidant activity in addition to muscle damage. Ten women (age: 38.7 ± 7.8 years; height: 163.81 ± 4.4 cm; body mass 76.0 ± 11.6 kg) and nine men (age: 41.2. ± 9.7 years; height: 177.4 ± 5...
October 5, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/28981378/morinda-citrifolia-leaf-extract-enhances-osteogenic-differentiation-through-activation-of-wnt-%C3%AE-catenin-signaling
#17
Hanna Gu, Kanitsak Boonanantanasarn, Moonkyu Kang, Ikhwi Kim, Kyung Mi Woo, Hyun-Mo Ryoo, Jeong-Hwa Baek
Morinda citrifolia (Noni) leaf is an herbal medicine with application in the domestic treatment of a broad range of conditions, including bone fracture and luxation. However, the basic mechanism underlying the stimulation of osteogenic differentiation by Noni leaf extract remains poorly understood. This study aimed to examine the effect of this extract on osteogenic differentiation and the mechanism by which Noni leaf extract enhances osteogenic differentiation. Aqueous extract of Noni leaves was prepared, and rutin and kaempferol-3-O-rutinoside were identified to be two of its major components...
October 5, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/28976801/alpha-lipoic-acid-shows-promise-to-improve-migraine-in-patients-with-insulin-resistance-a-6-month-exploratory-study
#18
Cinzia Cavestro, Giorgio Bedogni, Filippo Molinari, Silvia Mandrino, Eugenia Rota, Maria Cristina Frigeri
Alpha-lipoic acid (ALA) is known to lower insulin resistance (IR), which is common among migraineurs. To assess the effect of ALA on headache in migraineurs with IR, we performed an exploratory study on a cohort of patients with migraine, followed at our Headache Center. The 32 patients took ALA 400 mg b.i.d. for 6 months in addition to their on-going treatment. The percentage of patients with a reduction of at least 50% of the attacks was 0.53 (confidence interval [95% CI] 0.36-0.70) at 2 months, 0.56 (0...
October 4, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/28976796/neuroprotective-effects-of-luteolin-against-spinal-cord-ischemia-reperfusion-injury-by-attenuation-of-oxidative-stress-inflammation-and-apoptosis
#19
Jian Fu, Haibin Sun, Yongzhe Zhang, Wei Xu, Chuan Wang, Yanwei Fang, Jianhui Zhao
Luteolin (LU) is a widely distributed flavonoid with multitarget effects. The objective of this study was to determine whether LU could reduce the ischemia-reperfusion injury of the spinal cord (SCII) in a rat model. Forty-eight rats were divided into four groups: sham, SCII, SCII+L-LU (50 mg/kg), and SCII+H-LU (100 mg/kg). Abdominal aortic occlusion was carried out for 40 min in all groups. Hindlimb motor functions were evaluated using the Tarlov scoring system. Nissl and terminal deoxynucleotidyl transferase-mediated dUTP biotin nick end labeling (TUNEL) staining were used to detect cell survival and apoptosis in the spinal cord...
October 4, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/28956702/the-effect-of-anthocyanin-rich-purple-vegetable-diets-on-metabolic-syndrome-in-obese-zucker-rats
#20
Hala M Ayoub, Mary Ruth McDonald, James Alan Sullivan, Rong Tsao, Mathew Platt, Jeremy Simpson, Kelly A Meckling
Consumption of highly colored fruits and vegetables rich in anthocyanins has been associated with numerous health benefits. Purple carrots (PC) and purple potatoes (PP) have higher anthocyanin concentrations and higher biological activities compared with less pigmented cultivars. We hypothesized that substitution of the majority of carbohydrate in a high fat diet with PP or PC, for 8 weeks, would improve insulin resistance and hypertension, major components of metabolic syndrome, compared with orange carrots (OC), white potatoes (WP) or a control, high fat, sucrose-rich diet (HFD) in obese Zucker rats...
September 28, 2017: Journal of Medicinal Food
journal
journal
33053
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"