journal
MENU ▼
Read by QxMD icon Read
search

Climacteric: the Journal of the International Menopause Society

journal
https://www.readbyqxmd.com/read/30407085/optimizing-quality-of-life-in-perimenopause-lessons-from-the-east
#1
X Wang, S Ran, Q Yu
As global life expectancy improves, women are expected to spend more than one-third of their lives in the status of menopause. In China, many women suffer from menopausal symptoms during this period, which impacts their well-being and quality of life. However, most Chinese women simply endure menopausal symptoms. Since the Chinese Menopause Society was founded in 1999, several versions of the guidelines for menopause management and menopausal hormone therapy (MHT) have been published; international cooperation has strengthened; menopause-related activities have been advocated; and popular knowledge of menopause and MHT has gradually improved...
November 8, 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/30392388/effects-of-concurrent-exercise-on-cardiometabolic-status-during-perimenopause-the-flamenco-project
#2
I Coll-Risco, M Borges-Cosic, P Acosta-Manzano, D Camiletti-Moirón, P Aranda, V A Aparicio
OBJECTIVES: The aim of this study was to evaluate the influence of a 4-month concurrent exercise training program on cardiometabolic status in perimenopausal women. METHODS: The participants (n = 150) were randomized into counseling (n = 75) and exercise (n = 75) groups. The exercise group followed 4-month (3 days/week, 60 min/session) concurrent training. The counseling group attended conferences on a healthy lifestyle. We determined plasma glucose, total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), triglycerides, and C-reactive protein, and measured blood pressure and the resting heart rate...
November 5, 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/30380950/cause-or-prevention-of-breast-cancer-with-estrogens-analysis-from-tumor-biologic-data-growth-kinetic-model-and-women-s-health-initiative-study
#3
R J Santen, W Yue
The existing medical literature suggests that estrogens may cause breast cancer but, paradoxically, can also prevent this neoplasm under specific circumstances. Appropriate interpretation of this complex data requires an understanding of emerging concepts of tumor biology. A substantial body of data, including animal models and epidemiologic studies, suggests that estrogens contribute to the development of breast cancer. Additionally, pre-clinical experiments indicate that the responsible mechanisms include both estrogen receptor α-dependent and -independent effects (ERα-dependent and ERα-independent effects)...
November 1, 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/30380946/endocrinopathies-and-cardiopathies-in-patients-with-turner-syndrome
#4
Z A Allybocus, C Wang, Hr Shi, Qh Wu
Ovarian dysgenesis, short stature, and infertility are common features of Turner syndrome (TS). Endocrinopathies and cardiopathies are less common, but may induce significant complications, and are the leading cause of mortality in TS patients. Endocrine abnormality including osteoporosis occurs in up to 60% of patients, hypothyroidism at an incidence of 3.2%, and impaired glucose metabolism with variable incidence depending on the age group. Estrogen therapy and growth hormone therapy, alone or combined, improve height and bone mass in TS patients...
November 1, 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/30380961/sexual-quality-of-life-in-men-and-women-after-cancer
#5
L R Schover
More than 60% of people treated for cancer have long-term sexual dysfunction. However, fewer than 25% of those with sexual problems get help from a health professional. Although cancer-related sexual problems usually begin with physiological damage from cancer treatment, a patient's coping skills and the quality of the sexual relationship are crucial in sexual rehabilitation. Barriers to care for people treated for cancer include a lack of discussion with the oncology team. In repeated surveys, fewer than half of patients recall discussing sex or fertility with their care providers, even during informed consent...
October 31, 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/30380948/effects-of-different-menopausal-hormone-replacement-regimens-on-body-composition-in-chinese-women
#6
Y Deng, W Xue, Y Wang, S Zhu, X Ma, A Sun
PURPOSE: The aim of this study was to determine the effects of different menopausal hormone therapy regimens on body composition in healthy postmenopausal Chinese women. MATERIALS AND METHODS: One hundred and twenty-three healthy postmenopausal Chinese women were randomly assigned to either group A (0.625 mg conjugated equine estrogens [CEE] plus 100 mg micronized progesterone [MP]), group B (0.3 mg CEE plus 100 mg MP), or group C (0.625 mg CEE plus 10 mg dydrogesterone)...
October 31, 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/30378441/case-report-of-the-first-successful-cryopreserved-ovarian-tissue-retransplantation-in-china
#7
X Ruan, J Du, M Korell, W Kong, D Lu, F Jin, Y Li, Y Dai, C Yin, S Yan, M Gu, A O Mueck
Ovarian tissue cryopreservation and retransplantation has been offered as a fertility preservation approach for over a decade. At least 130 live births have been reported after frozen-thawed ovarian tissue transplantation worldwide. The first International Fertility Protection Center in China was established in 2015. Until now no live birth has been reported. However, we are able to report the first Chinese successful retransplantation of cryopreserved ovarian tissue (September 2016) in a woman with squamous cell cervical carcinoma...
October 31, 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/30372631/psychometric-evaluation-of-electronic-diaries-assessing-side-effects-of-hormone-therapy
#8
S Tatlock, L Abraham, A Bushmakin, M Moffatt, N Williamson, C Coon, R Arbuckle
OBJECTIVES: Postmenopausal women (PMW) can experience side-effects (breast pain/tenderness and vaginal spotting/bleeding) associated with estrogen plus progestin therapies (EPTs). To assess these outcomes, the Breast Pain and Tenderness Daily Diary (BPT-DD) and the Vaginal Bleeding and Spotting Daily Diary (VBS-DD) were developed for electronic completion. This study evaluated the psychometric properties of the diaries. METHODS: The eDiaries were completed daily for 28 days by 202 PMW experiencing breast pain/tenderness and/or vaginal spotting/bleeding while on EPTs...
October 29, 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/30299973/authors-reply
#9
D A S Bocardi, V S Pereira-Baldon, C H J Ferreira, M A Avila, A C S Beleza, P Driusso
No abstract text is available yet for this article.
October 9, 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/30296854/royal-jelly-does-not-prevent-bone-loss-but-improves-bone-strength-in-ovariectomized-rats
#10
S Shimizu, H Matsushita, A Minami, H Kanazawa, T Suzuki, K Watanabe, A Wakatsuki
OBJECTIVE: Royal jelly (RJ) has been used for medical and nutritional purposes, and previous studies have indicated that it may have estrogenic activity. The present study investigated the effects of RJ on bone metabolism in ovariectomized (OVX) rats. METHODS: Rats (12 weeks old) were randomly divided into four groups, namely Baseline, Sham, OVX, and OVX + RJ groups. Rats in the Baseline group were killed immediately, whereas rats in the OVX and OVX + RJ groups underwent bilateral ovariectomy and those in the Sham group underwent sham operation...
October 9, 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/30296850/menopausal-hormone-therapy-and-breast-cancer-what-is-the-evidence-from-randomized-trials
#11
H N Hodis, P M Sarrel
The relationship between menopausal hormone therapy (HT) and breast cancer is complex and further complicated by misinformation, perception, and overgeneralization of data. These issues are addressed in this mini-review through the lens of the Women's Health Initiative (WHI) that has colored the view of HT and breast cancer. In the WHI, unopposed conjugated equine estrogen (CEE) reduced breast cancer risk and mortality. In the WHI CEE plus continuously combined medroxyprogesterone acetate (MPA) trial, although the hazard ratio (HR) was elevated it was statistically non-significant for an association between CEE + MPA and breast cancer...
October 9, 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/30296186/thyroid-disease-in-the-perimenopause-and-postmenopause-period
#12
M M Uygur, T Yoldemir, D G Yavuz
The interpretation of thyroid function tests should be cautiously made during the perimenopause and postmenopause period bearing in mind that physiologic changes do exist in this group of women in terms of secretion and metabolism of thyrotropin and thyroid hormones. Moreover the incidence of thyroid disorders increases in postmenopausal and elderly women. There is no consensus for screening postmenopausal women even though there is well-known evidence about the effect of thyroid status on cognitive function, cardiovascular risk, bone turnover, and longevity...
October 8, 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/30296172/the-use-of-estradiol-metered-dose-transdermal-spray-in-clinical-practice
#13
T Fait, A Fialova, Z Pastor
OBJECTIVE: The aim of this study was to evaluate the use of novel estradiol metered-dose transdermal spray (EMDTS) in the treatment of acute climacteric syndrome. METHODS: A multicenter open-label trial was conducted with a 24-week intervention. EMDTS 1.53 mg was given to symptomatic menopausal women. The Menopause Rating Scale (MRS) was used to assess the climacteric syndrome severity. The Friedman non-parametric test and a post-hoc test with Bonferroni correction were used for statistical evaluation...
October 8, 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/30295111/evaluation-of-a-crosswalk-between-the-european-quality-of-life-five-dimension-five-level-and-the-menopause-specific-quality-of-life-questionnaire
#14
C Coon, A Bushmakin, S Tatlock, N Williamson, M Moffatt, R Arbuckle, L Abraham
OBJECTIVES: Postmenopausal (PM) women taking therapies using estrogens plus progestogens (EPTs) can experience side effects (breast pain, vaginal spotting/bleeding). Sensitivity of the European Quality of Life Five Dimension Five Level (EQ-5D-5L) in measuring quality of life of PM women experiencing side effects of EPTs is unknown. A crosswalk between the Menopause-Specific Quality of Life (MENQOL) questionnaire and the EQ-5D-5L was assessed. METHODS: The measures were administered to 352 PM women (side effects = 202; control = 75; untreated = 75) in a non-interventional study...
October 8, 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/30295093/concerns-about-the-review-of-vaginal-progesterone-and-the-vaginal-first-pass-effect
#15
Gian Carlo Di Renzo
No abstract text is available yet for this article.
October 8, 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/30295091/gynecological-endocrinological-aspects-in-women-carriers-of-brca1-2-gene-mutations
#16
A Doren, A Vecchiola, B Aguirre, P Villaseca
Women carriers of mutations in the genes BRCA1 and BRCA2 coding for tumor suppressor proteins are at high risk of developing breast and ovarian cancers. Hereditary breast and ovarian cancers due to BRCA pathogenic mutations occur at earlier ages: mean age 43 years at diagnosis of breast cancer for BRCA1 mutations; onset of ovarian cancer up to 10-21% by age 50 years. Preventive strategies are then defined in the reproductive years. The National Comprehensive Cancer Network (NCCN) guidelines define that BRCA1/2 genetic testing should begin with the affected cancer individual (BRCA1/2 full sequencing); then, family members should be tested for the specific gene mutation found...
October 8, 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/30295082/author-s-reply
#17
Michelle P Warren
No abstract text is available yet for this article.
October 8, 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/30295077/does-anti-m%C3%A3-llerian-hormone-predict-change-in-menopausal-symptoms-following-risk-reducing-salpingo-oophorectomy-a-prospective-observational-study
#18
R F M Vermeulen, M van Beurden, K N Gaarenstroom, T Teunis, J M Kieffer, N K Aaronson, G G Kenter, C M Korse
OBJECTIVES: The aim of this study was to investigate whether serum anti-Müllerian hormone (AMH) predicts symptom burden after risk-reducing salpingo-oophorectomy (RRSO) in order to individualize counseling. METHODS: Patient-reported menopausal symptoms, sexual functioning, and psychological distress (depression and anxiety) were assessed 1 day before (T0) and 6 weeks (T1) and 7 months (T2) after RRSO. AMH was assessed before RRSO. Multivariable regression analysis was used to investigate the association between AMH and short-term and long-term change in symptom burden following RRSO...
October 8, 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/30277095/multichannel-electromyography-for-the-assessment-of-pelvic-floor-muscle-function
#19
Kristina Drusany Staric, Vita Zacesta, Corrado Cescon, Amerigo Vitagliano, Petra Bukovec
No abstract text is available yet for this article.
October 2, 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/30232913/correlation-of-plasma-microrna-21-expression-and-bone-turnover-markers-in-postmenopausal-women
#20
T Perksanusak, K Panyakhamlerd, N Hirankarn, A Suwan, A Vasuratna, N Taechakraichana
OBJECTIVES: This study assessed the correlation of plasma microRNA-21 expression and bone turnover markers (BTMs: CTx, P1NP) in healthy Thai postmenopausal women. We secondarily compared microRNA-21 expression between participants with normal and low bone mineral density (BMD: osteopenia and osteoporosis). METHODS: Postmenopausal women who had never been diagnosed with fracture or never used anti-osteoporosis drugs were included in this study. Baseline characteristics were collected from all 195 participants...
September 20, 2018: Climacteric: the Journal of the International Menopause Society
journal
journal
33040
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"