journal
Journals Climacteric : the Journal of t...

Climacteric : the Journal of the International Menopause Society

https://read.qxmd.com/read/38482825/correction
#1
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
March 14, 2024: Climacteric: the Journal of the International Menopause Society
https://read.qxmd.com/read/38415712/genital-chronic-graft-versus-host-disease-an-unmet-need-that-requires-trained-gynecologists
#2
JOURNAL ARTICLE
M Á Martínez-Maestre, C Castelo-Branco, A M Calderón, I Espigado, J A Pérez-Simón, C González-Cejudo
OBJECTIVE: Menopause and chronic graft-versus-host disease (cGvHD) are the leading causes of morbidity after allogeneic hematopoietic stem cell transplantation (alloHSCT). Genitalia are one of the target organs of cGvHD causing sexual dysfunction and local symptoms, which may impair women's quality of life. The aim of this study is to describe the prevalence and clinical characteristics of genital cGvHD. METHODS: A retrospective cross-sectional observational study was performed including 85 women with alloHSCT...
February 28, 2024: Climacteric: the Journal of the International Menopause Society
https://read.qxmd.com/read/38415685/the-lady-study-epidemiological-characteristics-of-prevalent-and-new-genitourinary-syndrome-of-menopause-cases-in-greece
#3
JOURNAL ARTICLE
I Lambrinoudaki, N Mili, A Augoulea, E Armeni, N Vlahos, T Mikos, G Grimbizis, A Rodolakis, S Athanasiou
OBJECTIVE: The genitourinary syndrome of menopause (GSM) is often underdiagnosed and undertreated despite its significant impact on postmenopausal quality of life. We assessed the prevalence of GSM and associated symptoms in Greek perimenopausal/postmenopausal women attending gynecology clinics. METHODS: Four hundred and fifty women, aged 40-70 years (93.1% postmenopausal), attending three gynecology clinics at university hospitals completed a validated questionnaire and underwent pelvic examination...
February 28, 2024: Climacteric: the Journal of the International Menopause Society
https://read.qxmd.com/read/38353251/resistance-training-effects-on-healthy-postmenopausal-women-a-systematic-review-with-meta-analysis
#4
JOURNAL ARTICLE
N González-Gálvez, J M Moreno-Torres, R Vaquero-Cristóbal
The aim of this systematic review with meta-analysis was to evaluate the effects of resistance training on physical fitness, physiological variables and body composition of postmenopausal women. The present systematic review was performed in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) statement and was registered in PROSPERO. A total of 12 studies were included. The literature search was performed in PubMed, Web of Science and EBSCO. Randomized control trials were included...
February 14, 2024: Climacteric: the Journal of the International Menopause Society
https://read.qxmd.com/read/38345304/higher-testosterone-is-associated-with-higher-hdl-cholesterol-and-lower-triglyceride-concentrations-in-older-women-an-observational-study
#5
JOURNAL ARTICLE
S R Davis, Z N Azene, A M Tonkin, R L Woods, J J McNeil, R M Islam
OBJECTIVE: This study aimed to determine whether concentrations of testosterone and its main precursor after menopause, dehydroepiandrosterone (DHEA), are associated with lipoproteins and other lipids in community-dwelling older women. METHODS: The Sex Hormones in Older Women (SHOW) study was an observational study of 6358 Australian women, aged at least 70 years, with no prior major adverse cardiovascular event who had sex hormones measured by liquid chromatography-tandem mass spectrometry...
February 12, 2024: Climacteric: the Journal of the International Menopause Society
https://read.qxmd.com/read/38318859/vaginal-dryness-a-review-of-current-understanding-and-management-strategies
#6
REVIEW
J K K Mark, S Samsudin, I Looi, K H Yuen
The issue of vaginal dryness in genitourinary syndrome of menopause (GSM) and its pervasive impact on women's quality of life is often overlooked. Extensive surveys conducted worldwide reveal limited understanding of vaginal dryness among public and health-care providers. Physician knowledge on menopause medicine varies globally, highlighting the need for standardized training. Effective communication between physicians and patients plays a crucial role in diagnosing and treating GSM symptoms. There are multiple treatment options to improve vaginal lubrication, including hormonal and non-hormonal therapies, along with lifestyle modifications...
February 6, 2024: Climacteric: the Journal of the International Menopause Society
https://read.qxmd.com/read/38318796/allelic-variants-of-the-estrogen-receptor-genes-and-frailty-phenotype-in-postmenopausal-women
#7
JOURNAL ARTICLE
A Monllor-Tormos, A García-Vigara, O Morgan, M-Á García-Pérez, J J Tarín, A Cano
OBJECTIVE: The prevalence of frailty has been related to menopause. Our main objective was to investigate whether single nucleotide polymorphisms (SNPs) of the estrogen receptor (ER) ER <mml:math xmlns:mml="https://www.w3.org/1998/Math/MathML"><mml:mi>α</mml:mi><mml:mi> </mml:mi></mml:math> and ER <mml:math xmlns:mml="https://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mi>β</mml:mi></mml:mrow></mml:math> genes were related to the frailty phenotype in a population of community-dwelling postmenopausal women...
February 6, 2024: Climacteric: the Journal of the International Menopause Society
https://read.qxmd.com/read/38308574/genitourinary-symptoms-and-sexual-function-in-women-with-primary-ovarian-insufficiency
#8
JOURNAL ARTICLE
J E Blümel, P Chedraui, M S Vallejo, M Dextre, A Elizalde, C Escalante, A Monterrosa-Castro, M Ñañez, E Ojeda, C Rey, D Rodríguez, M A Rodrigues, C Salinas, K Tserotas
OBJECTIVE: There are limited studies on urogenital symptoms in women who experience menopause before the age of 40 years due to primary ovarian insufficiency (POI) or bilateral oophorectomy (surgical POI). This study aimed to compare the urogenital symptoms, including sexuality, of women with POI to those without the condition. METHODS: This cross-sectional study conducted was in seven Latin American countries, in which postmenopausal women (with POI and non-POI) were surveyed with a general questionnaire, the Menopause Rating Scale (MRS) and the six-item Female Sexual Function Index (FSFI-6)...
February 3, 2024: Climacteric: the Journal of the International Menopause Society
https://read.qxmd.com/read/38288691/an-ethical-assessment-of-compounded-bioidentical-hormone-therapy
#9
JOURNAL ARTICLE
R P Kauffman, E J MacLaughlin, L A Courtney, D D Vineyard
The use of compounded bioidentical hormone therapy (cBHT) continues to grow in popularity despite the availability of many US Food and Drug Administration-approved hormone products produced in different formulations and dosages. Numerous claims made by proponents of cBHT are not substantiated by properly designed studies. Valid concerns about purity, efficacy, bioavailability and safety of cBHT have been raised. Since patient welfare is the first duty of health professionals, promoting and prescribing cBHT as first-line therapy violates a number of ethical tenets of medical and pharmacy practice and should be discouraged without a compelling reason...
January 30, 2024: Climacteric: the Journal of the International Menopause Society
https://read.qxmd.com/read/38275172/effect-and-mechanism-of-recombinant-human-fibroblast-growth-factor-18-on-osteoporosis-in-ovx-mice
#10
JOURNAL ARTICLE
P Y Lu, M Huang, M H Shao, J X Hu, C Y Ding, Y J Feng, M Zhang, H P Lin, H S Tian
OBJECTIVES: This study aimed to investigate the effect and the mechanism of recombinant human fibroblast growth factor 18 (rhFGF18) on postmenopausal osteoporosis. METHODS: The effect of rhFGF18 on the proliferation and apoptosis of osteoblasts and the mechanism underlying such an effect was evaluated using an oxidative stress model of the MC3T3-E1 cell line. Furthermore, ovariectomy was performed on ICR mice to imitate estrogen-deficiency postmenopausal osteoporosis...
January 26, 2024: Climacteric: the Journal of the International Menopause Society
https://read.qxmd.com/read/38275167/effectiveness-and-safety-of-menopause-treatments-pitfalls-of-available-evidence-and-future-research-need
#11
JOURNAL ARTICLE
B H Al Wattar, E Rogozińska, C Vale, D Fisher, I Petersen, S Nicum, D Bannington, V Talaulikar, N Freemantle
By 2050 more than 1.6 billion women worldwide will be of post-reproductive age, with >75% reporting severe menopausal symptoms. The last few years saw a gradual uplift in public awareness reaffirming the health needs of women with menopause. Still, effective translation of available evidence on menopause treatments is hindered by several methodological limitations and poor research conduct. We argue that a paradigm shift is required in menopause research to address the remaining knowledge gap and guide safe evidence-based care provision...
January 26, 2024: Climacteric: the Journal of the International Menopause Society
https://read.qxmd.com/read/38265057/authorization-of-anastrazole-to-prevent-breast-cancer-in-postmenopausal-women-a-bad-idea
#12
JOURNAL ARTICLE
S J Glynne, A Z Bluming
Anastrazole has recently been approved for the prevention of breast cancer in high-risk women in the UK. When given to high-risk women anastrazole halves the risk of developing breast cancer but doesn't reduce the risk of breast cancer death and is associated with significant harms. Women need to be counselled about both the benefits and risks associated with anastrazole use to enable an informed treatment choice.
January 24, 2024: Climacteric: the Journal of the International Menopause Society
https://read.qxmd.com/read/38251874/obesity-and-sexual-health-focus-on-postmenopausal-women
#13
REVIEW
F Barbagallo, L Cucinella, L Tiranini, P Chedraui, A E Calogero, R E Nappi
Menopause is a cardiometabolic transition with many women experiencing weight gain and redistribution of body fat. Hormonal changes may affect also several dimensions of well-being, including sexual function, with a high rate of female sexual dysfunction (FSD), which displays a multifactorial etiology. The most important biological factors range from chronic low-grade inflammation, associated with hypertrophic adipocytes that may translate into endothelial dysfunction and compromised blood flow through the genitourinary system, to insulin resistance and other neuroendocrine mechanisms targeting the sexual response...
January 22, 2024: Climacteric: the Journal of the International Menopause Society
https://read.qxmd.com/read/38251861/randomized-trial-treatment-of-genitourinary-syndrome-of-menopause-using-radiofrequency
#14
JOURNAL ARTICLE
A Joris, V Di Pietrantonio, J Praet, K Renard, A-C Verduyn, F Buxant, S Rozenberg
OBJECTIVE: A randomized controlled study was conducted to evaluate the safety and efficacy of radiofrequency treatment in postmenopausal women not willing to use or presenting a contraindication for menopause hormone therapy (MHT) and suffering from genitourinary syndrome of menopause (GSM). METHODS: A prospective randomized open study evaluated the effect of radiofrequency treatment versus a gel (control group) in postmenopausal women suffering from GSM. Patients were assessed at baseline and after 10-12 weeks of treatment for severity of vulvovaginal atrophy, dyspareunia, pH, vaginal smear maturation index, Vaginal Health Index and Female Sexual Function Index...
January 22, 2024: Climacteric: the Journal of the International Menopause Society
https://read.qxmd.com/read/38241059/low-thrombin-generation-in-postmenopausal-women-using-estetrol
#15
JOURNAL ARTICLE
L Morimont, M Didembourg, C Bouvy, M Jost, M Taziaux, Y Oligschlager, M van Rooijen, U Gaspard, J-M Foidart, J Douxfils
OBJECTIVE: Estetrol (E4) represents a novel estrogen of interest to relieve vasomotor symptoms. E4 activates the nuclear estrogen receptor α (ERα) but antagonizes the estradiol ERα-dependent membrane-initiated steroid signaling pathway. The distinct pharmacological properties of E4 could explain its low impact on hemostasis. This study aimed to assess the effect of E4 on coagulation in postmenopausal women, using the thrombin generation assay (TGA). METHODS: Data were collected from a multicenter, randomized, placebo-controlled, dose-finding study in postmenopausal women (NCT02834312)...
January 19, 2024: Climacteric: the Journal of the International Menopause Society
https://read.qxmd.com/read/38231656/prevalence-of-poor-body-image-and-its-correlation-with-self-esteem-and-depression-in-middle-aged-women
#16
JOURNAL ARTICLE
R Satwik, D Sinha, B Tiwari
OBJECTIVE: This study aimed to determine the prevalence and predictors of poor body image and its influence on low self-esteem and depression in middle-aged women. METHODS: The study was a cross-sectional survey of 372 women using a predesigned online questionnaire. Main outcome measures were mean scores on the nine-point body image scale (BIS) and prevalence of poor body image (BIS ≥ 10). Significant sociodemographic, physical and mental health predictors of BIS ≥ 10 were established using logistic regression analysis...
January 17, 2024: Climacteric: the Journal of the International Menopause Society
https://read.qxmd.com/read/38197401/progesterone-and-not-estrogens-or-androgens-causes-breast-cancer
#17
JOURNAL ARTICLE
H J T Coelingh Bennink, F Z Stanczyk
No abstract text is available yet for this article.
January 10, 2024: Climacteric: the Journal of the International Menopause Society
https://read.qxmd.com/read/38174697/closing-the-gap-cardiovascular-disease-in-women
#18
REVIEW
M Nathani, B Vogel, R Mehran
Cardiovascular disease (CVD) in women remains understudied, under-recognized, underdiagnosed and undertreated. Initiatives such as the Lancet Women and Cardiovascular Disease Commission help to identify sex and gender-related gaps in research, care and outcomes and to guide next steps in addressing them. This article highlights important aspects of the Lancet Commission report and expands on the evidence and proposed strategies for reducing the global burden of CVD in women. Furthermore, the article explores the benefits of cross-specialty collaborations for the treatment and prevention of CVD in women and discusses the impact of gender-related disparities in academic cardiology...
January 4, 2024: Climacteric: the Journal of the International Menopause Society
https://read.qxmd.com/read/38174425/pregnancy-associated-risk-factors-for-future-cardiovascular-disease-early-prevention-strategies-warranted
#19
JOURNAL ARTICLE
T S Mikkola, O Ylikorkala
We summarize convincing evidence that future cardiovascular disease (CVD) risk increases one-fold to four-fold for women with a history of pregnancy complicated by hypertensive disorders, gestational diabetes, fetal growth restriction, placental abruption and preterm birth. A concomitant occurrence of two or more complications in the same pregnancy further potentiates the risk. These women should be informed of their future CVD risks during the postpartum check-up taking place after delivery, and also, if needed, treated, for example, for persisting high blood pressure...
January 4, 2024: Climacteric: the Journal of the International Menopause Society
https://read.qxmd.com/read/38164918/impact-of-vaginal-estriol-on-serum-hormone-levels-a-systematic-review
#20
REVIEW
A Kolokythas, C Betschart, D Wunder, H Janka, P Stute
The genitourinary syndrome of menopause (GSM) affects up to 84% of postmenopausal women and may significantly reduce the quality of life in some. For symptom relief, there are several non-hormonal and hormonal vaginal products available. In Europe, vaginal estriol (E3) is the most frequently chosen estrogen for GSM treatment. The aim of this systematic review was to assess the impact of vaginal E3 on serum sex hormone levels, an outcome that has been previously used to assess safety in similar products. In our review, we did not find any alterations in serum estrone, estradiol, testosterone, progesterone and sex hormone binding globulin levels after vaginal E3 application...
January 2, 2024: Climacteric: the Journal of the International Menopause Society
journal
journal
33040
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.