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Journal of ECT

Marine Mondino, Florence Sauvanaud, Jérôme Brunelin
Some 25% to 30% of patients with schizophrenia report auditory verbal hallucinations (AVHs) that fail to respond adequately to antipsychotic treatments. In such cases, transcranial direct current stimulation (tDCS) has been proposed as a therapeutic option. Here, we aim to provide an exhaustive review of the literature examining the clinical effects of tDCS on AVH in patients with schizophrenia. A systematic search in the PubMed and Web of Science databases yielded 14 results, 7 randomized controlled trials (RCTs) and 7 open-label studies...
July 17, 2018: Journal of ECT
Vanteemar S Sreeraj, Venkataram Shivakumar, Selvaraj Sowmya, Anushree Bose, Hema Nawani, Janardhanan C Narayanaswamy, Ganesan Venkatasubramanian
Transcranial alternating current stimulation (tACS), a noninvasive brain stimulation technique that uses low-intensity alternating current, has been postulated to be a potential therapeutic option in treating the cognitive deficits in schizophrenia. Transcranial alternating current stimulation synchronizes the neural oscillations to the applied stimulation frequency in the stimulated cortical regions. In this report, we have reviewed the literature pertinent to the clinical application of tACS in psychiatric disorders; in addition, we have described the clinical use of online theta tACS in a schizophrenia patient with cognitive deficits...
July 17, 2018: Journal of ECT
Lucia Angela Smith-Martinez, Lauren Nicole Chatham, Purushothaman Muthukanagaraj
No abstract text is available yet for this article.
July 17, 2018: Journal of ECT
Jian Wang, Fidel Vila-Rodriguez, Wei Jiang, Yian-Ping Ren, Chang-Ming Wang, Xin Ma
INTRODUCTION: Major depressive disorder is a prevalent and debilitating condition that afflicts millions of people worldwide. Magnetic seizure therapy (MST) is a promising convulsive neurostimulation treatment for depression with fewer cognitive adverse effects than electroconvulsive therapy. METHODS: A small case series of patients recruited as part of an open-label clinical trial is presented. Patients with depression underwent an accelerated MST protocol (aMST) consisting of 1 treatment per day for 6 consecutive weekdays...
July 3, 2018: Journal of ECT
Leah D Fryml, Christopher G Pelic, Ron Acierno, Peter Tuerk, Matthew Yoder, Jeffrey J Borckardt, Natasha Juneja, Matthew Schmidt, Kathryn L Beaver, Mark S George
OBJECTIVES: This is a small preliminary but novel study assessing the feasibility of repetitive transcranial magnetic stimulation (rTMS) delivery to veterans with posttraumatic stress disorder (PTSD) while they simultaneously receive prolonged exposure (PE) therapy. METHODS: A prospective, randomized, double-blinded, active sham-controlled design combined weekly sessions of rTMS and standard PE at the Veterans Administration Hospital. Eight adult patients received a full course of protocol-driven PE therapy and were randomly assigned to receive either rTMS or sham rTMS...
June 26, 2018: Journal of ECT
Vincent Khung Hoon Wong, Phern Chern Tor, Donel M Martin, Yee Ming Mok, Colleen Loo
OBJECTIVE: Electroconvulsive therapy (ECT) is an effective treatment in mania. However, there is little evidence regarding the use of ultrabrief right unilateral (RUL-UB) ECT in treatment of acute manic episodes. The aim of this study was to report on the effectiveness and cognitive profile of ECT in bipolar mania, including a sample who received RUL-UB ECT. METHODS: This naturalistic study retrospectively collected data in 33 patients who received ECT with concurrent antipsychotics for mania between October 1, 2014, and July 30, 2016...
June 26, 2018: Journal of ECT
Dimitry Francois, Tiffany Huang
No abstract text is available yet for this article.
June 26, 2018: Journal of ECT
Camila Bonin Pinto, Beatriz Teixeira Costa, Dante Duarte, Felipe Fregni
Transcranial direct current stimulation (tDCS) modulates spontaneous neuronal activity that can generate long-term neuroplastic changes. It has been used in numerous therapeutic trials showing significant clinical effects especially when combined with other behavioral therapies. One area of intensive tDCS research is chronic pain. Since the initial tDCS trials for chronic pain treatment using current parameters of stimulation, more than 60 clinical trials have been published testing its effects in different pain syndromes...
June 26, 2018: Journal of ECT
Brandon M Kitay, Rachel B Katz, Samuel T Wilkinson, Robert B Ostroff
No abstract text is available yet for this article.
June 26, 2018: Journal of ECT
Jean-Philippe Miron, Véronique Desbeaumes Jodoin, Marie-Pierre Fournier-Gosselin, Paul Lespérance
No abstract text is available yet for this article.
June 26, 2018: Journal of ECT
Puneet Narang, Alexis Swenson, Steven Lippmann
No abstract text is available yet for this article.
June 25, 2018: Journal of ECT
Anne Sauvaget, Emmanuel Poulet, Antonio Mantovani, Samuel Bulteau, Philippe Damier, Baptiste Moutaud, Mariano Paternoster, Andrea de Bartolomeis, Giordano DʼUrso
The proven effectiveness of neuromodulation and stimulation techniques for the management of psychiatric disorders has brought strongly needed innovation in psychiatry, given the high prevalence and high costs of treatment resistance. Although evidence-based guidelines in neuromodulation have been implemented to improve the clinical efficacy, safety, and research procedures, practical suggestions on how to design a psychiatric neuromodulation unit (PNU) are not available in the scientific literature. In this contribution, we have combined the results of a literature search with the suggestions of clinical psychiatrists, managers, and bioethicists who have had firsthand experience in building a PNU...
June 25, 2018: Journal of ECT
Samuel T Wilkinson, Robert Rosenheck
No abstract text is available yet for this article.
June 12, 2018: Journal of ECT
Lucas Borrione, Adriano H Moffa, Donel Martin, Colleen K Loo, Andre R Brunoni
Major depressive disorder is a severe, refractory mental disorder. Only one third of patients treated with antidepressants achieve remission after 3 trials, while subject to adverse effects. Therefore, the investigation of alternative treatments is paramount. The aim of this systematic review was to summarize the most recent evidence of transcranial direct current stimulation (tDCS) intervention for the acute phase of major depressive disorder. A PubMed search was performed including the terms "transcranial direct current stimulation" OR "transcranial direct stimulation" OR "tDCS" AND "major depressive disorder" OR "major depression" OR "depression" AND "trial...
June 12, 2018: Journal of ECT
Shyam Sundar Arumugham, Subhasini Vs, Madhuri Hn, Vinay B, Malvika Ravi, Eesha Sharma, Jagadisha Thirthalli, Y C Janardhan Reddy
OBJECTIVE: The current study investigated the efficacy of low-frequency repetitive transcranial magnetic stimulation (rTMS) over bilateral presupplementary motor area (pre-SMA) in patients suffering from obsessive-compulsive disorder (OCD) with partial/poor response to pharmacotherapy, in a double-blinded randomized sham controlled trial. METHOD: Forty subjects with OCD, who were on stable medications with partial/poor response to pharmacotherapy were randomly divided into 2 groups (n = 20 in each group), to receive either active or sham low-frequency rTMS over bilateral pre-SMA...
June 12, 2018: Journal of ECT
Charlotte J Stagg, Andrea Antal, Michael A Nitsche
Direct current stimulation is a neuromodulatory noninvasive brain stimulation tool, which was first introduced in animal and human experiments in the 1950s, and added to the standard arsenal of methods to alter brain physiology as well as psychological, motor, and behavioral processes and clinical symptoms in neurological and psychiatric diseases about 20 years ago. In contrast to other noninvasive brain stimulation tools, such as transcranial magnetic stimulation, it does not directly induce cerebral activity, but rather alters spontaneous brain activity and excitability by subthreshold modulation of neuronal membranes...
June 5, 2018: Journal of ECT
Mengqing Xia, Junjie Wang, Jianhua Sheng, Yingying Tang, Chunyan Li, Kelvin Lim, Bin He, Chunbo Li, Yifeng Xu, Jijun Wang
OBJECTIVE: Electroconvulsive therapy (ECT) has often been applied to augment antipsychotics for schizophrenia patients. However, the underpinning mechanism is still unclear. Previous studies of major depressive disorder reported an increase in γ-aminobutyric acid (GABA) after ECT. The present study investigated the effects of ECT on medial prefrontal GABA in schizophrenia using a proton magnetic resonance spectroscopy. METHODS: Inpatients fulfilling the diagnostic criteria for schizophrenia (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition) were assigned to 2 groups, ECT group (n = 14) receiving ECT plus antipsychotic drugs (APD) and drug group (n = 17) only receiving antipsychotic drugs...
June 5, 2018: Journal of ECT
Pilar Cristancho, Nicholas T Trapp, Shan H Siddiqi, David Dixon, J Philip Miller, Eric J Lenze
Clinical trials using left-sided repetitive transcranial magnetic stimulation (rTMS) report remission rates of 14% to 32.6%. A large percentage of patients would not achieve remission with standard rTMS treatment. The question of what clinicians should do when a patient is not responding to standard high-frequency (HF) left-sided rTMS remains unanswered. This prospective case series examines whether crossover to bilateral stimulation enhances antidepressant outcomes in patients not responding to unilateral rTMS...
June 5, 2018: Journal of ECT
Véronique Desbeaumes Jodoin, François Richer, Jean-Philippe Miron, Marie-Pierre Fournier-Gosselin, Paul Lespérance
BACKGROUND: Treatment-resistant depression (TRD) is a serious chronic condition disabling patients functionally and cognitively. Chronic vagus nerve stimulation (VNS) is recognized for the management of TRD, but few studies have examined its long-term effects on cognitive dysfunction in unipolar and bipolar resistant depression. OBJECTIVE: The purpose of this study was to assess the course of cognitive functions and clinical symptoms in a cohort of patients treated with VNS for TRD...
June 4, 2018: Journal of ECT
Eveline M Veltman, Sophie van Hulten, Jos Twisk, Annemiek Dols, Eric van Exel, Max L Stek, Pascal Sienaert, Filip Bouckaert, Roos C van der Mast, Didi Rhebergen
INTRODUCTION: Electroconvulsive therapy (ECT) is an important and effective treatment for depression. However, research on course trajectories of depressive symptoms during ECT is limited. Insight into putative differences in speed of response of depressive symptom dimensions may enable clinicians to optimally inform patients and their relatives. Therefore, we aim to examine course trajectories of depressive symptom dimensions in depressed older persons during ECT. METHODS: Data were derived from the Mood Disorders in Elderly treated with Electro Convulsive Therapy study, including 110 persons, aged 55 years or more, with a current diagnosis of major depressive disorder and referred for ECT...
May 29, 2018: Journal of ECT
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