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Journal of Oral Science

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https://www.readbyqxmd.com/read/28529281/the-expression-and-significance-of-the-hoxa7-gene-in-oral-squamous-cell-carcinoma
#1
Xiaofeng Duan, Hao Chen, Hong Ma, Yufeng Song
The aim of this study was to examine the expression of HOXA7 in oral squamous cell carcinoma (OSCC) and its correlation with clinical features. Sixty tissue specimens were collected from 60 OSCC patients who underwent surgical treatment at the Stomatological Hospital affiliated to Guizhou Medical University. Sixty specimens of normal oral tissue were also collected from 60 age- and sex-matched healthy controls. Expression of HOXA7 was assessed by real time polymerase chain reaction and immunohistochemistry...
May 19, 2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28529280/alternative-methods-to-visual-and-radiographic-examinations-for-approximal-caries-detection
#2
Naif Abogazalah, Masatoshi Ando
A shift in caries prevalence from occlusal surfaces to approximal surfaces has been demonstrated by epidemiological studies. Two recent meta-analyses evaluated the performance of visual examination and radiography for carious lesion detection, and reported low sensitivity but high specificity for early approximal caries detection. This suggests that the conventional methods have a higher risk of failing to detect approximal lesions. Consequently, in caries susceptible populations, there is a risk of progression of non-cavitated lesions to irreversible tooth destruction before the lesions are detected...
May 19, 2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28529279/comparing-the-occlusal-contact-area-of-individual-teeth-during-low-level-clenching
#3
Hideta Nishimori, Takashi Iida, Hirona Kamiyama, Yoshihiro Komoda, Ryoko Obara, Takashi Uchida, Misao Kawara, Osamu Komiyama
The aim of this study was to investigate the occlusal contact area (OCA) in individual teeth during low-level tooth clenching in 24 healthy participants. Before measurements were made, the 100% maximum voluntary contraction (MVC) was determined. At baseline, all subjects were instructed to close their mouth and touch the opposing teeth with minimal force. Occlusal contact was recorded during three jaw motor tasks (baseline, 20% MVC, and 40% MVC) using a blue silicone material. OCA thickness was determined from images and defined on five levels: level 1 (0-149 µm), level 2 (0-89 µm), level 3 (0-49 µm), level 4 (0-29 µm), and level 5 (0-4 µm)...
May 19, 2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28529278/morphological-evaluation-of-artificial-caries-affected-dentin-after-applying-fcp-complex
#4
Ritsuko Mashiko, Go Inoue, Toru Nikaido, Junji Tagami
FCP-COMPLEX is a newly-developed solution that contains fluoride, calcium, and phosphoric acid. It has the potential to reinforce caries-affected dentin. The purpose of this study was to evaluate the effect of FCP-COMPLEX on the morphology of bovine artificial caries-affected dentin (ACAD). FCP-COMPLEX, 2% sodium fluoride solution, and distilled water were applied to bovine ACAD and the effect on acid-induced damage was observed. Scanning electron microscopy was used to evaluate morphology after acid application...
May 19, 2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28049968/polyacrylic-resins-regulate-transcriptional-control-of-interleukin-6-gp80-and-gp130-genes-in-human-gingival-fibroblasts
#5
Bruna Borelli, Fernando Zarone, Virginia Rivieccio, Francesco Riccitiello, Michele Simeone, Roberto Sorrentino, Sandro Rengo, Gianrico Spagnuolo, Alfredo Procino
Studies have failed to identify the molecular mechanisms that regulate the genotoxic and cytotoxic effects of methacrylate resins, which are important in the biocompatibility of dental materials. Interleukin (IL)-6 has a crucial role in the control of acute-phase protein response during inflammation. In humans, the synthesis and release of two major acute-phase proteins, C-reactive protein and serum amyloid A, are regulated by IL-6. This study focused on IL-6 and activation of its receptors gp80 and gp130 in human gingival fibroblasts in order to assess the effects of the commercial acid resins Jet Kit, Unifast, and Duralay on control of inflammation...
March 31, 2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28049967/stimulated-salivary-flow-rate-and-oral-health-status
#6
Yoshihiro Shimazaki, Bohan Fu, Koji Yonemoto, Sumio Akifusa, Yukie Shibata, Toru Takeshita, Toshiharu Ninomiya, Yutaka Kiyohara, Yoshihisa Yamashita
This study examined the relationship between stimulated salivary flow rate and oral health status in an adult population. Multinomial multivariate logistic regression analysis was used to examine the associations of salivary flow rate with dental caries status and periodontal status at the individual level among 2,110 Japanese adults with ≥10 teeth. Then, a spline model was used to examine the nonlinear relationship between salivary flow rate and teeth with dental caries or periodontal disease in multilevel analysis...
March 31, 2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28049966/five-year-longitudinal-study-of-dental-caries-risk-associated-with-streptococcus-mutans-and-streptococcus-sobrinus-in-individuals-with-intellectual-disabilities
#7
Yuki Oda, Fumiko Hayashi, Atsuko Wakita, Yukiko Nagatani, Mitsugi Okada
Streptococcus mutans (S. mutans) and Streptococcus sobrinus (S. sobrinus) are important etiologic agents in human dental caries. Using quantitative real-time polymerase chain reaction assays for the presence of those strains, we examined 145 outpatients with intellectual disability (ID), calculated the proportion of each of these strains to total bacteria, and compared dental caries incidence over 5 years. Plaque samples were collected from all erupted tooth sites, and dental examinations were performed annually to determine numbers of decayed, missing, and filled teeth (DMFT score; World Health Organization caries diagnostic criteria)...
March 31, 2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28049965/effect-of-pre-drilling-on-intraosseous-temperature-during-self-drilling-mini-implant-placement-in-a-porcine-mandible-model
#8
Zsuzsanna Gurdán, László Vajta, Ákos Tóth, Edina Lempel, Árpád Joób-Fancsaly, József Szalma
This in vitro study investigated intraos seous heat production during insertion, with and without pre-drilling, of a self-drilling orthodontic mini-implant. To measure temperature changes and drilling times in pig ribs, a special testing apparatus was used to examine new and worn pre-drills at different speeds. Temperatures were measured during mini-implant placement with and without pre-drilling. The average intraosseous temperature increase during manual mini-implant insertion was similar with and without pre-drilling (11...
March 31, 2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28049964/effect-of-nonsurgical-periodontal-treatment-on-clinical-periodontal-variables-and-salivary-resistin-levels-in-obese-asians
#9
Zohaib Akram, Nor A Baharuddin, Rathna D Vaithilingam, Zubaidah H A Rahim, Karuthan Chinna, Vignes G Krishna, Roslan Saub, Syarida H Safii
This study investigated changes in periodontal outcomes after nonsurgical periodontal treatment (NSPT) and evaluated associations of change in salivary resistin level with periodontal outcomes in obese Malaysians with chronic periodontitis. Sixty-two obese adults with chronic periodontitis were randomly divided into a test group (n = 31), which received NSPT, and a control group (n = 31), which received no treatment. Plaque score (PS), gingival bleeding index (GBI), probing pocket depth (PPD), and clinical attachment loss (CAL) were measured at baseline and at 6 and 12 weeks after NSPT...
March 31, 2017: Journal of Oral Science
https://www.readbyqxmd.com/read/27725370/effects-of-polymerization-method-on-flexural-and-shear-bond-strengths-of-a-fiber-reinforced-composite-resin
#10
Hiroaki Yanagida, Naomi Tanoue, Yoshito Minesaki, Yoko Kamasaki, Taku Fujiwara, Hiroyuki Minami
This study investigated the effects of indirect composite polymerization on the postcuring mechanical properties of a fiber-reinforced composite. An indirect composite seated on glass fibers preimpregnated with polymerized monomer was polymerized by 1) photoirradiation using a halogen-fluorescent polymerizing unit for 5 min, 2) method 1 plus secondary heating at 100°C for 15 min, 3) photoirradiation using a metal halide light unit for 60 s, or 4) preliminary polymerization using a halogen light unit for 20 s followed by method 3...
March 31, 2017: Journal of Oral Science
https://www.readbyqxmd.com/read/27725369/prevalence-and-risk-factors-for-peri-implant-diseases-in-japanese-adult-dental-patients
#11
Yorimasa Ogata, Yohei Nakayama, Junichi Tatsumi, Takehiko Kubota, Shuichi Sato, Tetsuya Nishida, Yasuo Takeuchi, Tokuya Onitsuka, Ryuji Sakagami, Takenori Nozaki, Shinya Murakami, Naritoshi Matsubara, Maki Tanaka, Toshiaki Yoshino, Junya Ota, Taneaki Nakagawa, Yuichi Ishihara, Taichi Ito, Atsushi Saito, Keiko Yamaki, Etsuko Matsuzaki, Toshirou Hidaka, Daisuke Sasaki, Takashi Yaegashi, Tadashi Yasuda, Toshiaki Shibutani, Kazuyuki Noguchi, Hisao Araki, Noriharu Ikumi, Yukihiko Aoyama, Hideki Kogai, Kenji Nemoto, Shinji Deguchi, Takashi Takiguchi, Matsuo Yamamoto, Keita Inokuchi, Takatoshi Ito, Takashi Kado, Yasushi Furuichi, Mikimoto Kanazashi, Kazuhiro Gomi, Yukie Takagi, Keita Kubokawa, Nobuo Yoshinari, Yoshiaki Hasegawa, Tetsushi Hirose, Toshinaga Sase, Hirokazu Arita, Toshiro Kodama, Kitetsu Shin, Yuichi Izumi, Hiromasa Yoshie
We investigated the prevalences and risk factors for peri-implant diseases in Japanese adult dental patients attending a follow-up visit at dental hospitals or clinics as part of their maintenance program. This cross-sectional multicenter study enrolled patients with dental implants who attended regular check-ups as part of a periodontal maintenance program during the period from October 2012 through September 2013. Patients with implants with at least 3 years of loading time were included in the study. The condition of peri-implant tissue was examined and classified into the following categories: healthy, peri-implant mucositis, and peri-implantitis...
March 31, 2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28637992/ten-year-clinical-observation-of-a-porcelain-laminate-veneer-seated-with-biological-tissue-adaptation-bta-technique
#12
Kenji Tsubota
This clinical report describes the use of biological tissue adaptation technique for placement of a porcelain laminate veneer in a 50-year-old woman. The author developed this prosthetic technique to facilitate alignment of gingival levels for esthetic purposes. The laminate veneer was seated on the maxillary central incisor with an adhesive system. Although the margin of the restoration overhangs, no gingival inflammation or recession has been observed during a follow-up period of 10 years and 9 months.
2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28637991/low-intensity-pulsed-ultrasound-inhibits-lipopolysaccharide-induced-il-6-and-rankl-expression-in-osteoblasts
#13
Mayu Nagao, Natsuko Tanabe, Soichiro Manaka, Tadahiro Takayama, Takayuki Kawato, Go Torigoe, Jumpei Sekino, Naoya Tsukune, Manami Ozaki, Masao Maeno, Naoto Suzuki, Shuichi Sato
Periodontal disease is caused by inflammation induced by Porphyromonas gingivalis (P.g.) lipopolysaccharide (LPS) and involves expression of proinflammatory cytokines such as interleukin (IL)-1, IL-6, tumor necrosis factor-α, and receptor activator of nuclear factor kappa B ligand (RANKL), which are implicated in bone resorption. Low-intensity pulsed ultrasound (LIPUS) is commonly used in the treatment of bone fracture. However, the mechanisms by which LIPUS inhibits LPS-induced inflammatory cytokines are poorly understood...
2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28637990/effect-of-the-leukotriene-receptor-antagonist-montelukast-on-orthodontic-tooth-movement
#14
Hossam Asaad, Rabab Al-Sabbagh, Darem Al-Tabba, Omar Kujan
Asthma is a chronic inflammatory disease, and its prevalence is relatively high among children. Optimal management of asthma often requires long-term pharmacotherapy; however, the effects of these medications on orthodontic treatment is uncertain. We evaluated the effects of the leukotriene LTD4 receptor antagonist montelukast on orthodontic tooth movement in an animal model. Eight mongrel dogs were given montelukast for periods up to 4 weeks. An orthodontic force of 150-200 g was applied to move the second and fourth premolars toward the site of the extracted third premolar...
2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28637989/hla-a-26-a-30-and-hla-drb1-10-could-be-predictors-of-nasopharyngeal-carcinoma-risk-in-high-risk-tunisian-families
#15
Nehla Mokni-Baizig, Yosr Gorgi, Mohamed Elghourabi, Mouna Makhlouf, Hamouda Boussen, Said Gritli, Michèle Elmay, Amor Gamoudi, Ahmed Elmay
We investigated human leukocyte antigen (HLA) profiles for Tunisians with nasopharyngeal carcinoma (NPC), their families, and a sample of unrelated healthy Tunisians in order to identify HLA specificities associated with familial NPC. HLA-A, -B, and -DRB1 typing was successful for 36 NPC patients, 72 unaffected family members, and 130 community controls, and the chi square or Fisher exact test was used to compare allele frequencies between cases and controls. We observed a consistent protective effect of HLA-DRB1*10 on NPC development...
2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28637988/comparison-of-gene-expression-profiles-of-gingival-carcinoma-ca9-22-cells-and-colorectal-adenocarcinoma-ht-29-cells-to-identify-potentially-important-mediators-of-slpi-induced-cell-migration
#16
Tsuyoshi Takamura, Hisashi Suguro, Yoshikazu Mikami, Takashi Iwase, Yusuke Komiyama, Kayo Kuyama, Kazuo Komiyama, Hiderou Oki
Secretory leukocyte protease inhibitor (SLPI) is a serine protease inhibitor whose expression level is positively correlated with tumor aggressiveness and metastatic potential. However, the mechanism underlying SLPI-induced enhancement of malignant phenotype is not completely understood. The malignancy of cancer cells is highly dependent on cell migration activity. Our previous study revealed that gingival carcinoma Ca9-22 cells, but not colorectal adenocarcinoma HT-29 cells, expressed SLPI. Therefore, we investigated the migration activity of these two cell types to understand the nature of SLPI-mediated tumor aggressiveness and metastatic potential...
2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28637987/three-dimensional-finite-element-analysis-of-the-effects-of-implant-diameter-and-photofunctionalization-on-peri-implant-stress
#17
Tetsuo Ohyama, Hiroyasu Yasuda, Norio Shibuya, Satomi Tadokoro, Shinya Nakabayashi, Shunsuke Namaki, Yaeko Hara, Takahiro Ogawa, Tomohiko Ishigami
Previous finite element analyses of peri-implant stress assumed a bone-implant contact (BIC) ratio of 100%, even though the BIC ratio is known to be approximately 50% or less. However, the recent development of ultraviolet treatment of titanium immediately before use, known as photofunctionalization, significantly increased the BIC ratio, to 98.2%. We used a unique finite element analysis model that enabled us to examine the effects of different BIC ratios on peri-implant stress. A three-dimensional model was constructed under conditions of vertical or oblique loading, an implant diameter of 3...
2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28637986/the-logic-behind-the-use-of-fissure-sealant-retention-as-a-proxy-outcome-measure-for-dental-caries-prevention
#18
Steffen Mickenautsch
Fissure sealant retention is traditionally considered as a proxy measure for caries prevention. This study investigated the logic behind this proposition, and its validity. A logical framework of the proposition was established. The mechanism of caries development was transferred into a Directed acyclic graph, and this was used to investigate the logical framework. The sensitivity and specificity of full sealant retention in the prediction of dental carious lesion development and the number of false positive/false negative prediction rates were computed...
2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28637985/three-dimensional-evaluation-of-the-location-of-the-mandibular-canal-using-cone-beam-computed-tomography-for-orthodontic-anchorage-devices
#19
Yasuki Uchida, Mitsuru Motoyoshi, Yasuhiro Namura, Noriyoshi Shimizu
This study investigated guidelines for placement of monocortical screws in the mandible, particularly the mandibular canal. In this study of 35 patients, we used cone-beam computed tomography to determine the distance from the alveolar crest to the superior border of the mandibular canal (DMC) and the shortest distance from the buccal and lingual cortex to the mandibular canal (attaining distance) in the areas between premolars (premolar area), between the second premolar and first molar (middle area), and between the first and second molars (molar area)...
2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28637984/anti-inflammatory-effect-of-rosuvastatin-decreases-alveolar-bone-loss-in-experimental-periodontitis
#20
Fatma Y Kırzıoğlu, Memduha Tözüm Bulut, Burak Doğan, Özlem Fentoğlu, Özlem Özmen, Süleyman A Çarsancaklı, Ayşe G Ergün, Muhsin Özdem, Hikmet Orhan
The effects of systemically administered rosuvastatin on alveolar bone loss (ABL), cytokine levels and oxidative status were investigated in rats with ligature-induced periodontitis. Rats were divided randomly into four groups: a non-ligated group (C); a non-ligated+rosuvastatin group (R); a ligated group (P); and a ligated+rosuvastatin group (PR). Ligatures were placed at the maxillary second molars, and rosuvastatin was administered for 14 days. After the rats had been euthanatized, histomorphometric and histological analyses were performed, and the serum levels of interleukin (IL)-1β, IL-10 and oxidant and antioxidant parameters (malondialdehyde [MDA], superoxide dismutase, glutathione, and glutathione peroxidase) were evaluted by enzyme-linked immunosorbent assay...
2017: Journal of Oral Science
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