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Journal of Clinical Densitometry

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https://www.readbyqxmd.com/read/29941355/glucocorticoid-induced-osteoporosis-management-challenges-in-older-patients
#1
REVIEW
Robert A Adler
Glucocorticoid-induced osteoporosis remains the most common type of secondary osteoporosis, mostly due to use of oral glucocorticoids rather than due to endogenous overproduction of cortisol. Partly because glucocorticoids are prescribed by a wide variety of clinicians for many different inflammatory disorders, only a minority of older individuals have adequate and timely assessment of their enhanced fracture risk, and fewer are offered treatment. Assessment should include bone density, the FRAX calculation, and, in many cases, images of the spine...
June 20, 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29954684/dxa-derived-lean-mass-includes-the-fat-free-component-of-adipose-tissue-impact-on-training-induced-changes-in-body-composition
#2
LETTER
Takashi Abe, Robert S Thiebaud, Jeremy P Loenneke
No abstract text is available yet for this article.
May 26, 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29776736/trabecular-bone-score-at-the-distal-femur-and-proximal-tibia-in-individuals-with-spinal-cord-injury
#3
Stacey Lobos, Anne Cooke, Gillian Simonett, Chester Ho, Steven K Boyd, W Brent Edwards
Rapid declines in bone mineral density (BMD) at the knee after spinal cord injury (SCI) are associated with an increased risk of fracture. Evaluation of bone quality using the trabecular bone score (TBS) may provide a complimentary measure to BMD assessment to examine bone health and fracture risk after SCI. The purpose of this study was to assess bone mineral density (BMD) and trabecular bone score (TBS) at the knee in individuals with and without SCI. Nine individuals with complete SCI (mean time since SCI 2...
April 24, 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29785933/a-comparison-of-peripheral-imaging-technologies-for-bone-and-muscle-quantification-a-review-of-segmentation-techniques
#4
REVIEW
Andy Kin On Wong, Sarah Lynn Manske
Musculoskeletal science has developed many overlapping branches, necessitating specialists from 1 area of focus to often require the expertise in others. In terms of imaging, this means obtaining a comprehensive illustration of bone, muscle, and fat tissues. There is currently a lack of a reliable resource for end users to learn about these tissues' imaging and quantification techniques together. An improved understanding of these tissues has been an important progression toward better prediction of disease outcomes and better elucidation of their interaction with frailty, aging, and metabolic disorders...
April 17, 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29729949/prevention-of-glucocorticoid-induced-osteoporosis-clinical-audit-to-evaluate-the-implementation-of-national-osteoporosis-guideline-group-2017-guidelines-in-a-primary-care-setting
#5
Matthew Carter
Treatment with glucocorticoids is the leading cause of drug-induced osteoporosis. National Osteoporosis Guideline Group (NOGG) 2017 guidelines advise a case-finding strategy for patients at risk. The aims of the audit were to evaluate the implementation of the NOGG 2017 guidelines for patients receiving long-term glucocorticoid therapy in a suburban general practice, to instigate changes to ensure 90% of patients are investigated and treated appropriately, and to evaluate impact at a 6-mo re-audit. Reporting Analysis and Intelligence Delivering Results (RAIDR) is a health-care intelligence tool accessing primary care clinical data...
April 12, 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29703658/lean-soft-tissue-mass-measured-using-dual-energy-x-ray-absorptiometry-is-an-effective-index-for-assessing-change-in-leg-skeletal-muscle-mass-following-exercise-training
#6
Taishi Midorikawa, Megumi Ohta, Suguru Torii, Shizuo Sakamoto
It is difficult to precisely and easily estimate the changes in skeletal muscle mass (SMM) following exercise training. We aimed to assess whether the change in lean soft tissue mass measured using dual-energy X-ray absorptiometry (DXA) reflects the change in SMM measured using magnetic resonance imaging (MRI) following exercise training in both the leg and trunk regions. Anthropometry, DXA, and MRI measurements of the trunk and leg regions were obtained in 10 male college sumo wrestlers before and after exercise training (mean duration between measurements: ~2 yr)...
April 4, 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29153384/dual-energy-x-ray-absorptiometry-quality-matters
#7
EDITORIAL
Diane Krueger, Neil Binkley, Sarah Morgan
No abstract text is available yet for this article.
April 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29102474/lumbar-spine-trabecular-bone-score-tbs-reflects-diminished-bone-quality-in-patients-with-diabetes-mellitus-and-oral-glucocorticoid-therapy
#8
Yunfeng Xue, Andrea L Baker, Shahla Nader, Philip Orlander, Anthony J Sanchez, James Kellam, Nahid J Rianon, Catherine G Ambrose
Trabecular bone score (TBS) is a texture parameter that measures the grayscale variation within dual-energy X-ray absorptiometry (DXA) images, and has been shown to significantly correlate with the 3-dimensional bone microarchitecture. The objective of this study was to determine whether TBS is a better clinical tool than traditionally used bone mineral density (BMD) to detect the skeletal deterioration seen in patients with diabetes (DM), patients undergoing oral glucocorticoid (GC) therapy, and patients who are both diabetic and taking steroids (GC + DM)...
April 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28988694/do-textiles-impact-dxa-bone-density-or-body-composition-results
#9
E Siglinsky, N Binkley, D Krueger
External artifacts can confound dual-energy X-ray absorptiometry (DXA) measurements. It is often accepted that garments free of metal do not affect DXA results; however, little data exist in this regard. It is plausible that some textiles absorb radiation and thereby alter DXA results. We hypothesized that some dense or synthetic textiles, for example, reflective materials, might alter DXA-measured bone and soft tissue mass. Hologic and GE Lunar spine phantoms and a Bioclinica prototype total body phantom were imaged on a GE Lunar iDXA and Prodigy densitometer...
April 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28918227/bone-remodeling-of-the-distal-femur-after-uncemented-total-knee-arthroplasty-a-2-year-prospective-dxa-study
#10
Mikkel Rathsach Andersen, Nikolaj S Winther, Thomas Lind, Henrik M Schrøder, Michael Mørk Petersen
Loss of bone stock as a response to the bone trauma, immobilization, and stress shielding related to joint replacement surgery increases the risk of fracture of the distal femur after total knee arthroplasty. Previous studies of uncemented femoral components have reported very high levels of bone loss in the distal femur. This study investigates the adaptive bone remodeling of the distal femur after uncemented total knee arthroplasty. We performed a 2-year follow-up of 53 patients (mean age 61.5 [38-70] years, F/M = 27/26, body mass index 29...
April 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28826886/risk-factors-for-fractures-identified-in-the-algorithm-developed-in-5-year-follow-up-of-postmenopausal-women-from-rac-ost-pol-study
#11
P Adamczyk, A Werner, M Bach, J Żywiec, A Czekajło, W Grzeszczak, B Drozdzowska, W Pluskiewicz
The aim of the study was to establish factors with an impact on fracture risk and to develop an algorithm to predict osteoporotic fracture. A total of 978 postmenopausal women from the epidemiological, population-based RAC-OST-POL study with a mean age of 65.7 ± 7.3 years were enrolled. At baseline, bone mineral density at hip and clinical risk factors for fracture were collected. Afterward, each person was asked annually on fracture incidence in the 5-year follow-up. Finally, data for complete 5-year observation were gathered for the group of 802 patients...
April 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28802981/errors-in-patient-positioning-for-bone-mineral-density-assessment-by-dual-x-ray-absorptiometry-effect-of-technologist-retraining
#12
Sasivimol Promma, Chanika Sritara, Saowanee Wipuchwongsakorn, Krisanat Chuamsaamarkkee, Chirawat Utamakul, Wichana Chamroonrat, Arpakorn Kositwattanarerk, Yoch Anongpornjossakul, Kanungnij Thamnirat, Boonsong Ongphiphadhanakul
Improper positioning is one of the factors that can lead to incorrect bone mineral density (BMD) results. This study aimed to assess the frequencies of erroneous positioning during three periods: before retraining of the technologists (BR), after retraining (AR), and at the current timepoint 8 years after retraining (C). The BMD images of the first 150 consecutive patients who underwent DXA of the lumbar spine and hip during each of the three periods were retrospectively reviewed. Patients were excluded if they had severe scoliosis, rendering proper positioning impossible...
April 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28801168/please-don-t-move-evaluating-motion-artifact-from-peripheral-quantitative-computed-tomography-scans-using-textural-features
#13
Timo Rantalainen, Paola Chivers, Belinda R Beck, Sam Robertson, Nicolas H Hart, Sophia Nimphius, Benjamin K Weeks, Fleur McIntyre, Beth Hands, Aris Siafarikas
Most imaging methods, including peripheral quantitative computed tomography (pQCT), are susceptible to motion artifacts particularly in fidgety pediatric populations. Methods currently used to address motion artifact include manual screening (visual inspection) and objective assessments of the scans. However, previously reported objective methods either cannot be applied on the reconstructed image or have not been tested for distal bone sites. Therefore, the purpose of the present study was to develop and validate motion artifact classifiers to quantify motion artifact in pQCT scans...
April 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28784276/role-of-apoe-gene-in-bone-mineral-density-and-incidence-of-bone-fractures-in-brazilian-postmenopausal-women
#14
Leticia S Souza, Neuza Felix Rochette, Diego França Pedrosa, Rafaella P Lopes Magnago, Teodiano B Freire Filho, Fernando Luiz H Vieira, Irani do Carmo F Fin, Sergio R Eis, Jones B Graceli, Leticia B A Rangel, Ian V Silva
Osteoporosis is one of the major diseases that affects mostly postmenopausal women. Despite being a multifactorial disease, some genes have been shown to play an important role in osteoporosis. Bone mineral density (BMD) is still largely used to diagnose it, although many other biomarkers are used to better follow the disease onset. It has been shown that the apolipoprotein E (APOE) gene could be a biomarker for risk of fractures as well as to predict lower BMD in patients with osteoporosis. The human APOE gene encodes 3 protein isoforms called ApoE2, ApoE3, and ApoE4, resulting in 4 possible genotypes, because they are a product of a single nucleotide polymorphism found in this gene...
April 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28712980/association-of-selective-serotonin-reuptake-inhibitors-and-bone-mineral-density-in-elderly-women
#15
Smita Saraykar, Vineeth John, Bo Cao, Matthew Hnatow, Catherine G Ambrose, Nahid Rianon
Depression and osteoporosis are 2 common comorbidities in geriatric patients. There are concerns about the deleterious effects of selective serotonin reuptake inhibitor (SSRI) antidepressant use on bone mineral density (BMD). We examined the association between SSRI use and BMD in elderly women (≥65 yr) referred to a geriatric osteoporosis clinic for bone health evaluation. Cross-sectional analyses using the general linear model were performed on data collected retrospectively from August 2010 to April 2015...
April 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28689879/nonstandard-lumbar-region-in-predicting-fracture-risk
#16
Dima Alajlouni, Dana Bliuc, Thach Tran, Nicholas Pocock, Tuan V Nguyen, John A Eisman, Jacqueline R Center
Femoral neck (FN) bone mineral density (BMD) is the most commonly used skeletal site to estimate fracture risk. The role of lumbar spine (LS) BMD in fracture risk prediction is less clear due to osteophytes that spuriously increase LS BMD, particularly at lower levels. The aim of this study was to compare fracture predictive ability of upper L1-L2 BMD with standard L2-L4 BMD and assess whether the addition of either LS site could improve fracture prediction over FN BMD. This study comprised a prospective cohort of 3016 women and men over 60 yr from the Dubbo Osteoporosis Epidemiology Study followed up for occurrence of minimal trauma fractures from 1989 to 2014...
April 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28687244/positive-association-of-obesity-and-insulin-resistance-with-bone-mineral-density-in-tunisian-postmenopausal-women
#17
Rim Cherif, Feten Mahjoub, Hela Sahli, Elhem Cheour, Laurence Vico, Mohsen Sakly, Nebil Attia
The association of bone mineral density (BMD) with obesity and insulin resistance remains unclear. This study aimed to explore these associations in Tunisian menopausal women. Eighty-one postmenopausal women were recruited. Data were analyzed for obese (N = 57) and non-obese women (N = 24) and for insulin-resistant (N = 43) and non insulin-resistant women (N = 36). Anthropometric and biochemical parameters were recorded. BMD in different sites and body composition were measured using dual-energy X-ray absorptiometry...
April 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28438404/quantitative-ultrasound-and-tibial-dysplasia-in-neurofibromatosis-type-1
#18
David A Stevenson, Heather Hanson, Austin Stevens, John Carey, David Viskochil, Xiaoming Sheng, Karen Wheeler, Hillarie Slater
Neurofibromatosis type 1 (NF1) is a common autosomal dominant disorder associated with unilateral anterolateral bowing with subsequent fracture and nonunion. In infancy, physiologic bowing of the lower leg can be confused with pathologic tibial dysplasia in NF1. Little is known about the bone physiology of the tibiae prior to fracture or predictors of fracture. The aim of this study was to characterize bone quality of bowed tibiae prior to fracture in NF1 using quantitative ultrasound (QUS). Bone quality was assessed on both tibiae (the non-bowed and bowed tibiae) using QUS to measure speed of sound (SOS) at the mid-shaft in 23 individuals with NF1...
April 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28427988/obesity-bariatric-surgery-and-vitamin-d
#19
REVIEW
Joao Lindolfo C Borges, Isabella Santiago de M Miranda, Marta M S Sarquis, Victoria Borba, Sergio Setsuo Maeda, Marise Lazaretti-Castro, Neil Blinkey
The high prevalence of obesity is a worldwide problem associated with multiple comorbidities, including cardiovascular diseases. Vitamin D deficiency with secondary hyperparathyroidism is common in obese individuals and can be aggravated after bariatric surgery. Moreover, there is no consensus on the optimal supplementation dose of vitamin D in postbariatric surgical patients. We present new data on the variability of 25(OH)D response to supplementation in postmenopausal obese women. It is important to recognize and treat vitamin D deficiency before bariatric surgery to avoid postoperative complications, such as metabolic bone disease with associated high fracture risk...
April 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28389068/bone-mineral-density-measurements-around-osseointegrated-implants-a-precision-study-and-validation-of-scan-protocol-for-transfemoral-amputees
#20
Rehne Lessmann Hansen, Bente Lomholt Langdahl, Peter Holmberg Jørgensen, Klaus Kjær Petersen, Kjeld Søballe, Maiken Stilling
Visual evaluation of bone changes around an osseointegration (OI) implant in femoral amputees examined on plain radiographs shows that periprosthetic bone resorption takes place during the first years after OI surgery, but the bone mineral density (BMD) change has not been previously quantified by dual-energy X-ray absorptiometry (DXA). Precision is vital when monitoring BMD changes around implants, and thus the aim of this study was to evaluate the precision and feasibility of a scan protocol for BMD measurements in proximity of OI implants...
April 2018: Journal of Clinical Densitometry
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