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Journal of Clinical Densitometry

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https://www.readbyqxmd.com/read/28438404/quantitative-ultrasound-and-tibial-dysplasia-in-neurofibromatosis-type-1
#1
David A Stevenson, Heather Hanson, Austin Stevens, John Carey, David Viskochil, Xiaoming Sheng, Karen Wheeler, Hillarie Slater
Neurofibromatosis type 1 (NF1) is a common autosomal dominant disorder associated with unilateral anterolateral bowing with subsequent fracture and nonunion. In infancy, physiologic bowing of the lower leg can be confused with pathologic tibial dysplasia in NF1. Little is known about the bone physiology of the tibiae prior to fracture or predictors of fracture. The aim of this study was to characterize bone quality of bowed tibiae prior to fracture in NF1 using quantitative ultrasound (QUS). Bone quality was assessed on both tibiae (the non-bowed and bowed tibiae) using QUS to measure speed of sound (SOS) at the mid-shaft in 23 individuals with NF1...
April 21, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28427988/obesity-bariatric-surgery-and-vitamin-d
#2
REVIEW
Joao Lindolfo C Borges, Isabella Santiago de M Miranda, Marta M S Sarquis, Victoria Borba, Sergio Setsuo Maeda, Marise Lazaretti-Castro, Neil Blinkey
The high prevalence of obesity is a worldwide problem associated with multiple comorbidities, including cardiovascular diseases. Vitamin D deficiency with secondary hyperparathyroidism is common in obese individuals and can be aggravated after bariatric surgery. Moreover, there is no consensus on the optimal supplementation dose of vitamin D in postbariatric surgical patients. We present new data on the variability of 25(OH)D response to supplementation in postmenopausal obese women. It is important to recognize and treat vitamin D deficiency before bariatric surgery to avoid postoperative complications, such as metabolic bone disease with associated high fracture risk...
April 17, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28389068/bone-mineral-density-measurements-around-osseointegrated-implants-a-precision-study-and-validation-of-scan-protocol-for-transfemoral-amputees
#3
Rehne Lessmann Hansen, Bente Lomholt Langdahl, Peter Holmberg Jørgensen, Klaus Kjær Petersen, Kjeld Søballe, Maiken Stilling
Visual evaluation of bone changes around an osseointegration (OI) implant in femoral amputees examined on plain radiographs shows that periprosthetic bone resorption takes place during the first years after OI surgery, but the bone mineral density (BMD) change has not been previously quantified by dual-energy X-ray absorptiometry (DXA). Precision is vital when monitoring BMD changes around implants, and thus the aim of this study was to evaluate the precision and feasibility of a scan protocol for BMD measurements in proximity of OI implants...
April 4, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28359675/measuring-marrow-density-and-area-using-peripheral-quantitative-computed-tomography-at-the-tibia-precision-in-young-and-older-adults-and-individuals-with-spinal-cord-injury
#4
Jenna C Gibbs, Zachary M Brown, Andy K O Wong, B Catharine Craven, Jonathan D Adachi, Lora M Giangregorio
The objective of this study was to compare the test-retest precision error for peripheral quantitative computed tomography (pQCT)-derived marrow density and marrow area segmentation at the tibia using 3 software packages. A secondary analysis of pQCT data in young adults (n = 18, mean ± standard deviation 25.4 ± 3.2 yr), older adults (n = 47, 71.8 ± 8.2 yr), and individuals with spinal cord injury (C1-T12 American Spinal Injury Association Impairment Scale, classes A-C; n = 19, 43...
March 27, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28302355/effects-of-short-term-calcium-supplementation-in-children-and-adolescents-with-phenylketonuria
#5
Nancy Y Y Tanaka, Marlene F Turcato, Carolina F Nicoletti, Carla B Nonino, Luciana D Martins, Odilon Iannetta, Carlos Tostes Guerreiro, Gisele G Santos, Júlio S Marchini
Reduction of bone mineral density and the risk of osteopenia have been reported to occur in phenylketonuria (PKU) patients. This study aimed to evaluate the short-term effects of calcium supplementation in phenylketonuric children and adolescents. The study included 18 patients with PKU aged 5-18 yr (61% male) under clinical and nutritional treatment. Evaluation of food intake, anthropometry, and biochemical and phalangeal quantitative ultrasound were performed before (phase 1) and after (phase 2) calcium supplementation (1000 mg/d) for 34 d...
March 13, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28302354/quadrant-analysis-of-quantitative-computed-tomography-scans-of-the-femoral-neck-reveals-superior-region-specific-weakness-in-young-and-middle-aged-men-with-type-1-diabetes-mellitus
#6
Takuma Kuroda, Koji Ishikawa, Takashi Nagai, Tomoyasu Fukui, Tsutomu Hirano, Katsunori Inagaki
We have previously shown that the intertrochanter of young and middle-aged patients with type 1 diabetes mellitus (T1DM) showed higher buckling ratio (an index of cortical instability) and lower volumetric bone mineral density (vBMD). However, we have not yet reported the detailed findings regarding the mechanical and density properties of the femoral neck. Therefore, we present a subanalysis of our previous study with the aim of further evaluating the middle third of the femoral neck via quadrant quantitative computed tomography in young and middle-aged patients with T1DM...
March 13, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28285742/peripheral-quantitative-computed-tomography-pqct-measures-contribute-to-the-understanding-of-bone-fragility-in-older-patients-with-low-trauma-fracture
#7
Hongyuan Jiang, Christopher J Yates, Alexandra Gorelik, Ashwini Kale, Qichun Song, John D Wark
Dual-energy X-ray absorptiometry (DXA) as currently used has limitations in identifying patients with osteoporosis and predicting occurrence of fracture. We aimed to express peripheral quantitative computed tomography (pQCT) variables of patients with low-trauma fracture as T-scores by using T-score scales obtained from healthy young women, and to evaluate the potential clinical utility of pQCT for the assessment of bone fragility. Fracture patients were recruited from a fracture liaison service at the Royal Melbourne Hospital...
March 9, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28258886/cross-calibrated-dual-energy-x-ray-absorptiometry-scanners-demonstrate-systematic-bias-in-pediatric-and-young-adult-females
#8
Jodi N Dowthwaite, Kristen A Dunsmore, Dongliang Wang, Paula F Rosenbaum, Tamara A Scerpella
Consistency of dual-energy X-ray absorptiometry (DXA) scan results is critical for data integrity. For pediatric subjects, the extent to which cross-calibration of DXA scanners alleviates model-to-model scanner differences is unclear. In the current study, DXA bone outcomes were compared for same-day measurements performed using different scanners, cross-calibrated to alleviate discrepancies (Hologic; Discovery A [DISCO] and QDR 4500W [QDR]). Interscanner differences were evaluated in approximately 130 females aged 8-24 yr...
February 28, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28256308/precision-of-second-generation-high-resolution-peripheral-quantitative-computed-tomography-intra-and-intertester-reproducibilities-and-factors-involved-in-the-reproducibility-of-cortical-porosity
#9
Ko Chiba, Narihiro Okazaki, Ayako Kurogi, Yusaku Isobe, Akihiko Yonekura, Masato Tomita, Makoto Osaki
High-resolution peripheral quantitative computed tomography (HR-pQCT) was upgraded to a second generation in 2014 with higher spatial resolution, faster scan time, and a different measurement algorithm. The purpose of this study was to investigate the precision of the second-generation HR-pQCT. The distal radius and tibia of 15 healthy men and women (age range of 20-74 yr, 8 men and 7 women) were scanned by second-generation HR-pQCT, and their geometry, bone mineral density (BMD), and the microstructure of trabecular and cortical bones were evaluated...
February 27, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28238606/comparison-of-associations-of-dxa-and-ct-visceral-adipose-tissue-measures-with-insulin-resistance-lipid-levels-and-inflammatory-markers
#10
John T Schousboe, Lisa Langsetmo, Ann V Schwartz, Brent C Taylor, Tien N Vo, Allyson M Kats, Elizabeth Barrett-Connor, Eric S Orwoll, Lynn M Marshall, Iva Miljkovic, Nancy E Lane, Kristine E Ensrud
Visceral adipose tissue (VAT) measured by computed tomography (CT) is related to insulin resistance, lipids, and serum inflammatory markers. Our objective was to compare the strength of the associations of VAT measured using dual-energy X-ray absorptiometry (DXA-VAT) and CT (CT-VAT) with insulin resistance, serum lipids, and serum markers of inflammation. For 1117 men aged 65 and older enrolled in the Osteoporotic Fractures in Men Study, the cross-sectional associations of DXA-VAT and CT-VAT with homeostasis model assessment of insulin resistance (homa2ir), C-reactive protein, and high-density lipoprotein (HDL) cholesterol were estimated with regression models and compared using a Hausman test...
February 23, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28233710/vitamin-d-deficiency-and-its-influence-on-bone-metabolism-and-density-in-a-brazilian-population-of-healthy-men
#11
Marlianne Leite Moreira, Leonardo Vieira Neto, Miguel Madeira, Renata Francioni Lopes, Maria Lucia Fleiuss Farias
Vitamin D supplementation is universal for postmenopausal women, but not for elderly men, in whom osteoporosis is also commonly neglected. This study aimed to evaluate vitamin D deficiency and its association with secondary hyperparathyroidism, bone resorption, and bone density in Brazilian men. A total of 120 men, 20-93 years, were evaluated for serum calcium, phosphorus, creatinine, 25-hydroxyvitamin D (25(OH)D), parathyroid hormone, biochemical markers of bone resorption (carboxy-terminal telopeptide, carboxy-terminal peptide of type I collagen), and bone mineral density (dual-energy X-ray absorptiometry)...
February 20, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28185765/proceedings-of-the-2016-santa-fe-bone-symposium-new-concepts-in-the-management-of-osteoporosis-and-metabolic-bone-diseases
#12
REVIEW
E Michael Lewiecki, John P Bilezikian, Susan V Bukata, Pauline Camacho, Bart L Clarke, Michael R McClung, Paul D Miller, John Shepherd
The Santa Fe Bone Symposium is an annual meeting of healthcare professionals and clinical researchers that details the clinical relevance of advances in knowledge of skeletal diseases. The 17th Santa Fe Bone Symposium was held in Santa Fe, New Mexico, USA, on August 5-6, 2016. The program included plenary lectures, oral presentations by endocrinology fellows, meet-the-professor sessions, and panel discussions, all aimed to provide ample opportunity for interactive discussions among all participants. Symposium topics included recent developments in the translation of basic bone science to patient care, new clinical practice guidelines for postmenopausal osteoporosis, management of patients with disorders of phosphate metabolism, new and emerging treatments for rare bone diseases, strategies to enhance fracture healing, and an update on Bone Health Extension for Community Healthcare Outcomes, using a teleconferencing platform to elevate the level of knowledge of healthcare professionals in underserved communities to deliver best practice care for skeletal diseases...
February 6, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28161223/genetic-polymorphisms-in-the-esr1-and-vdr-genes-do-not-correlate-with-osteoporosis-in-patients-with-familial-dysautonomia
#13
David Cheishvili, Channa Maayan, Daniel M Sapozhnikov, Elad Lax, Rivka Dresner-Pollak
One of the major clinical manifestations of familial dysautonomia (FD)-a rare, neurodegenerative, autosomal-recessive disorder-is a high incidence and early onset of osteoporotic bone fractures. Early diagnosis is essential to initiate preventative therapy in at-risk patients and thus improve quality of life. However, the current lack of understanding of the complex relationship between FD and osteoporosis etiology precludes early diagnosis, and as such, accurate predictors of osteoporosis development in FD patients remain to be determined...
February 1, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28153410/effectiveness-of-osteoporosis-self-assessment-tool-for-asians-in-screening-for-osteoporosis-in-healthy-males-over-40-years-old-in-china
#14
Ji-Yuan Huang, Wen-Zhong Song, Mei Huang
In this study, we evaluated the effectiveness of the Osteoporosis Self-assessment Tool for Asians (OSTA) in screening for osteoporosis in the elderly male population in the Chengdu area, China. The Lunar Prodigy Advance bone densitometer was used to measure the bone mineral density of 11,039 healthy males over the age of 40 years. Men with OSTA scores of >-1, -4 < OSTA ≤ -1, or ≤-4 were assigned to the low-risk, moderate-risk, or high-risk group, respectively. The T-scores measured with dual-energy X-ray absorptiometry at the different sites were compared across the groups...
January 30, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/27448496/prostate-cancer-and-fracture-identifying-at-risk-groups
#15
EDITORIAL
Stephen Paul Tuck
No abstract text is available yet for this article.
April 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/27423411/fracture-risk-differentially-modulated-by-trabecular-bone-score-according-to-ethnicity
#16
EDITORIAL
Charlles Heldan de Moura Castro, Vera Lúcia Szejnfeld
No abstract text is available yet for this article.
April 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/27210803/utility-of-osteoporosis-self-assessment-tool-as-a-screening-tool-for-predicting-osteoporosis-in-indian-men
#17
Khurshid A Bhat, Manisha Kakaji, Ashish Awasthi, Karambir Kumar, Kshtij Mishra, Manoj Shukla, Sushil K Gupta
The osteoporosis self-assessment tool (OSTA) predicts the risk of osteoporosis in an individual. It is a simple calculation-based tool [wt (kg) - age (yr)/5] and can be used for measuring bone mineral density (BMD). However, OSTA is influenced by ethnicity. We studied the performance of OSTA index as a screening tool for osteoporosis in 257 community-dwelling North Indian men above 50 yr age. Each subject underwent a detailed clinical, dietary, anthropometric, and biochemical assessment and bone density measurement using dual-energy X-ray absorptiometry...
April 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/27160503/ethnic-differences-in-trabecular-bone-score
#18
Rajesh K Jain, Disha K Narang, Didier Hans, Tamara J Vokes
Trabecular bone score (TBS), a noninvasive textural analysis of the lumbar spine dual-energy X-ray absorptiometry (DXA) image, has been shown to predict fractures in Caucasian (CA) populations but has not been thoroughly studied in African-American (AA) populations. The aim of this study was to compare the TBS in AAs and CAs and to assess whether TBS can be used to refine fracture risk stratification in AA patients. Eight hundred twenty-five women (390 AAs, 435 CAs) referred for bone mineral density (BMD) as part of their clinical care had measurements of the TBS, the BMD of the lumbar spine, total hip, and femoral neck, and vertebral fracture assessment for detection of vertebral fractures...
April 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/27140902/heterogeneity-in-spinal-bone-mineral-density-among-young-adults-from-three-eastern-provincial-capital-cities-in-mainland-china
#19
Xiao-Guang Cheng, Kai Li, Shan-Xing Ou, Guang-Yu Tang, Qian-Qian Wang, Chao Wang, Ling Wang, Wei Tian
This study compares spinal volumetric bone mineral density (vBMD) with spinal areal bone mineral density (aBMD) among young adults from 3 eastern provincial capital cities in Mainland China. A total of 416 young adults (age range: 20-40 yr) from 3 eastern provincial capital cities (Beijing, Shanghai, and Guangzhou) in Mainland China were recruited in this study. From each subject, the vBMD of the lumbar spine was measured by the Mindways quantitative computed tomography system. Moreover, the aBMD of the lumbar spine, measured by the dual-energy X-ray absorptiometry, was extracted from a previous multicenter large-scale study, and the 420 participants were matched by age, gender, height, weight, as well as geographic territory...
April 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/27117685/decreased-composite-indices-of-femoral-neck-strength-in-young-obese-men
#20
LETTER
César El Khoury, Hechmi Toumi, Eric Lespessailles, Antonio Pinti, Georges El Khoury, Ghassan Maalouf, Eddy Zakhem, Marie-Louise Ayoub, Eric Watelain, Rawad El Hage
No abstract text is available yet for this article.
April 2017: Journal of Clinical Densitometry
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