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Journal of Clinical Densitometry

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https://www.readbyqxmd.com/read/29229501/proceedings-of-the-2017-santa-fe-bone-symposium-insights-and-emerging-concepts-in-the-management-of-osteoporosis
#1
REVIEW
E Michael Lewiecki, John P Bilezikian, John J Carey, Richard M Dell, Catherine M Gordon, Steven T Harris, Michael R McClung, Paul D Miller, Michael Rosenblatt
The 18th Annual Santa Fe Bone Symposium was held on August 4-5, 2017, in Santa Fe, New Mexico, USA. The symposium convenes health-care providers and clinical researchers to present and discuss clinical applications of recent advances in research of skeletal diseases. The program includes lectures, oral presentations by endocrinology fellows, case-based panel discussions, and breakout sessions on topics of interest, with emphasis on participation and interaction of all participants. Topics included the evaluation and treatment of adult survivors with pediatric bone diseases, risk assessment and management of atypical femur fractures, nonpharmacologic strategies in the care of osteoporosis, and skeletal effects of parathyroid hormone with opportunities for therapeutic intervention...
November 20, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29103946/the-relevance-of-osteoclastic-and-osteoblastic-activity-markers-follow-up-in-patients-on-antiresorptive-osteoporosis-treatment
#2
Tanja N Smilic, Tatjana R Novakovic, Snezana R Markovic-Jovanovic, Ljiljana L J Smilic, Javorka S Mitic, Miodrag L Radunovic
In general, markers of bone formation and markers of bone resorption are changing synergistically, so the monitoring of any osteoclastic and any osteoblastic marker should reflect the rate of bone transformation. The aim of the study is to monitor the bone metabolism markers in postmenopausal women with osteoporosis and osteopenia along with the variations caused by the effects of bisphosphonate therapy. The study involved 55 women of average age of 57.95 years, with osteopenia or osteoporosis. The patients with osteoporosis were treated with bisphosphonates (75 mg once a week); the laboratory tests were performed before the treatment and 6 months later...
November 2, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29102474/lumbar-spine-trabecular-bone-score-tbs-reflects-diminished-bone-quality-in-patients-with-diabetes-mellitus-and-oral-glucocorticoid-therapy
#3
Yunfeng Xue, Andrea L Baker, Shahla Nader, Philip Orlander, Anthony J Sanchez, James Kellam, Nahid J Rianon, Catherine G Ambrose
Trabecular bone score (TBS) is a texture parameter that measures the grayscale variation within dual-energy X-ray absorptiometry (DXA) images, and has been shown to significantly correlate with the 3-dimensional bone microarchitecture. The objective of this study was to determine whether TBS is a better clinical tool than traditionally used bone mineral density (BMD) to detect the skeletal deterioration seen in patients with diabetes (DM), patients undergoing oral glucocorticoid (GC) therapy, and patients who are both diabetic and taking steroids (GC + DM)...
November 1, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29173816/the-prediction-of-body-composition-in-african-americans-from-spine-and-hip-dual-energy-absorptiometry
#4
Rajesh K Jain, Tamara Vokes
Body composition, the makeup of the body's fat and lean tissue, is associated with important health outcomes and provides useful clinical information. Although body composition can be measured with total body dual-energy X-ray absorptiometry (DXA), this is rarely performed. As an alternative to total body DXA measurement, methods for estimation of body composition have been developed. These methods use soft tissue measures from spine and hip DXA to predict body composition and include prediction equations previously published by Leslie and proprietary equations within General Electric densitometry software...
October 25, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29169662/effects-of-contrast-enhancement-on-in-body-calibrated-phantomless-bone-mineral-density-measurements-in-computed-tomography
#5
Nuran Abdullayev, Victor-Frederic Neuhaus, Grischa Bratke, Sebastian Voss, Nils Grosse Hokamp, Martin Hellmich, Barbara Krug, David Maintz, Jan Borggrefe
We aimed to test the potential of phantomless volumetric bone mineral density (PLvBMD) measurements for the determination of volumetric bone mineral density (vBMD) in routine contrast-enhanced computed tomography (CECT). We evaluated 56 tri-phasic abdominal computed tomography scans, including an unenhanced scan as well as defined CECT scans in the arterial and portalvenous phase. PLvBMD analysis was performed by 4 radiologists using an FDA-approved tool for phantomless evaluation of bone density (IntelliSpace, Philips, The Netherlands)...
October 23, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29056312/bone-geometric-properties-of-the-femoral-neck-in-underweight-eumenorrheic-women
#6
Nathalie Al Rassy, Joseph Matta, Fabienne Frenn, Ghassan Maalouf, Maroun Rizkallah, Falah Bachour, Amer Sebaaly, Pierre Hardouin, Christophe Chauveau, Rawad El Hage
The aim of this study was to describe femoral neck (FN) geometry among eumenorrheic underweight women around the age of peak bone mass. Proximal femur geometry and body composition were assessed in 12 underweight women and in 24 healthy controls using dual-energy X-ray absorptiometry. The Hip Structural Analysis program was used to determine bone geometry at the FN. The cross-sectional area (CSA) and the cross-sectional moment of inertia (CSMI) were significantly lower in underweight women than in controls (p < 0...
October 19, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29153384/dual-energy-x-ray-absorptiometry-quality-matters
#7
EDITORIAL
Diane Krueger, Neil Binkley, Sarah Morgan
No abstract text is available yet for this article.
October 18, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29054559/the-influence-of-reconstruction-kernel-on-bone-mineral-and-strength-estimates-using-quantitative-computed-tomography-and-finite-element-analysis
#8
Andrew S Michalski, W Brent Edwards, Steven K Boyd
Quantitative computed tomography has been posed as an alternative imaging modality to investigate osteoporosis. We examined the influence of computed tomography convolution back-projection reconstruction kernels on the analysis of bone quantity and estimated mechanical properties in the proximal femur. Eighteen computed tomography scans of the proximal femur were reconstructed using both a standard smoothing reconstruction kernel and a bone-sharpening reconstruction kernel. Following phantom-based density calibration, we calculated typical bone quantity outcomes of integral volumetric bone mineral density, bone volume, and bone mineral content...
October 17, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28988694/do-textiles-impact-dxa-bone-density-or-body-composition-results
#9
E Siglinsky, N Binkley, D Krueger
External artifacts can confound dual-energy X-ray absorptiometry (DXA) measurements. It is often accepted that garments free of metal do not affect DXA results; however, little data exist in this regard. It is plausible that some textiles absorb radiation and thereby alter DXA results. We hypothesized that some dense or synthetic textiles, for example, reflective materials, might alter DXA-measured bone and soft tissue mass. Hologic and GE Lunar spine phantoms and a Bioclinica prototype total body phantom were imaged on a GE Lunar iDXA and Prodigy densitometer...
October 5, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29111198/cumulative-effective-dose-and-cancer-risk-of-pediatric-population-in-repetitive-whole-body-scan-using-dual-energy-x-ray-absorptiometry
#10
Martin Law, Wang-Kei Ma, Eva Chan, Candy Mui, Vivian Ma, Wai-Yin Ho, Lawrance Yip, Wendy Lam
This study aims to quantitatively evaluate the cumulative effective dose and associated cancer risk of pediatric patients of US and Hong Kong population undergoing repetitive whole-body scans with dual-energy X-ray absorptiometry (DXA) during their diagnosis and follow-up periods. Organ-absorbed doses of pediatric patients undergoing DXA whole-body scan have been computer simulated using patient imaging parameters input to the Monte Carlo software PCXMC. Gender- and age-specific effective doses have been calculated with the simulated organ-absorbed doses using the ICRP-103 approach...
September 29, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29173817/adaptive-bone-remodeling-with-new-design-of-the-abg-stem-densitometric-study
#11
Jorge López-Subías, Juan J Panisello, Jesús M Mateo-Agudo, Marina Lillo-Adán, Antonio Herrera
To establish the pattern of bone remodeling caused by a cementless, anatomic implant, we intend to evaluate the changes in bone mineral density observed after surgery in the Gruen zones. A controlled, prospective study was carried out, in which a group of 37 patients with primary coxarthrosis were densitrometrically analyzed over the 1 year period following the implant of an ANATO stem (Stryker). The patient's healthy hip was taken as the control. Any differences in the remodeling pattern were compared according to age, body mass index, and implant size...
September 28, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28958825/evaluation-of-different-screening-tools-for-predicting-femoral-neck-osteoporosis-in-rural-south-indian-postmenopausal-women
#12
Kripa Elizabeth Cherian, Nitin Kapoor, Sahana Shetty, Dukhabandhu Naik, Nihal Thomas, Thomas V Paul
The measurement of bone mineral density by dual-energy X-ray absorptiometry scan is the "gold standard" for the diagnosis of osteoporosis, which has limited availability in many parts of India. This study was done to assess the diagnostic performance of 6 internationally validated tools (Simple Calculated Osteoporosis Risk Estimation [SCORE], age, bulk, one or never estrogen [ABONE], Osteoporosis Risk Assessment Instrument [ORAI] and Osteoporosis Self-Assessment Tool for Asians [OSTA], Fracture Risk Assessment Tool [FRAX®], and calcaneal quantitative ultrasound [QUS]) for the diagnosis of osteoporosis at the femoral neck (FN)...
September 25, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28943183/quantitative-ultrasound-of-the-mandible-as-a-novel-screening-approach-for-osteoporosis
#13
Anna Beattie, Seán Cournane, Ciarán Finucane, J Bernard Walsh, Leo F A Stassen
This study used an axial transmission quantitative ultrasound (QUS) device to assess mandibular bone strength. The aim of the study was first to establish the precision and repeatability of the axial transmission QUS measurement for a range of mandibular anatomic sites, and second to investigate the ability of the modality to differentiate between osteoporotic subjects and a control group. Three groups of adult Caucasian women were recruited: (1) healthy premenopausal women (n = 26), (2) healthy postmenopausal women (n = 48), and (3) women with osteoporosis (n = 53)...
September 21, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29107267/empowering-the-patient-while-developing-an-osteoporosis-management-strategy
#14
EDITORIAL
Ronald C Hamdy
No abstract text is available yet for this article.
October 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28965704/reversing-the-relationship-between-dual-energy-x-ray-absorptiometry-and-the-4-component-model-with-1-sign-flip
#15
LETTER
Bennett K Ng, Markus J Sommer, John A Shepherd
No abstract text is available yet for this article.
October 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28893468/chinese-herbal-medicine-for-osteoporosis-a-meta-analysis-of-randomized-controlled-trials
#16
REVIEW
Yong-Xiang Jin, Peng Wu, Yi-Fan Mao, Bo Wang, Jia-Feng Zhang, Wen-Liang Chen, Zhong Liu, Xiao-Lin Shi
Osteoporosis is a major public health problem in the elderly population. Several studies have suggested that Chinese herbal medicine has antiosteoporotic activities that might be beneficial for osteoporosis. This study aimed to assess the effectiveness of Chinese herbal medicine in osteoporosis patients. We comprehensively searched for randomized controlled trials (until December 2016) that compared Chinese herbal medicine with Western medicine in adults with osteoporosis and reported bone mineral densities (BMDs)...
October 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28807473/water-treatment-by-magnetic-field-increases-bone-mineral-density-of-rats
#17
Geraldo Balieiro Neto, Jair Rodini Engracia Filho, Bruna Rezende Silva Martins de Oliveira, Cássia Maria Molinaro Coelho, Lilian Francisco Arantes de Souza, Mario Jefferson Quirino Louzada
Water treatment using a magnetic field is an attractive but controversial issue with regard to its effects on human health. This study aimed to investigate the effects of water treatment using a magnetic field on the bone mineral density (BMD), bone mineral content (BMC), bone area (BA), bone resistance (BR), blood gas analysis, blood viscosity, and blood biochemical profile of rats. Forty-eight Wistar rats were divided into 2 groups: control (n = 24) and magnetic water-treated (n = 24). Each of these groups was subdivided into 3 groups to evaluate 3 consumption periods (15, 30, and 45 d)...
October 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28756995/an-investigation-into-the-differences-in-bone-density-and-body-composition-measurements-between-2-ge-lunar-densitometers-and-their-comparison-to-a-4-component-model
#18
Laura P E Watson, Michelle C Venables, Peter R Murgatroyd
We describe a study to assess the precision of the GE Lunar iDXA and the agreement between the iDXA and GE Lunar Prodigy densitometers for the measurement of regional- and total-body bone and body composition in normal to obese healthy adults. We compare the whole-body fat mass by dual-energy X-ray absorptiometry (DXA) to measurements by a 4-component (4-C) model. Sixty-nine participants, aged 37 ± 12 yr, with a body mass index of 26.2 ± 5.1 kg/cm(2), were measured once on the Prodigy and twice on the iDXA...
October 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28652104/quantifying-pelvic-periprosthetic-bone-remodeling-using-dual-energy-x-ray-absorptiometry-region-free-analysis
#19
Andrew M Parker, Lang Yang, Mohsen Farzi, José M Pozo, Alejandro F Frangi, J Mark Wilkinson
The gold standard tool for measuring periprosthetic bone mineral density (BMD) is dual-energy X-ray absorptiometry (DXA). However, resolution of the method is limited due to the aggregation of pixel data into large regions of interest for clinical and statistical analysis. We have previously validated a region-free analysis method (DXA-RFA) for quantitating BMD change at the pixel level around femoral prostheses. Here, we applied the DXA-RFA method to the pelvis, and quantitated its precision in this setting using repeated DXA scans taken on the same day after repositioning in 29 patients after total hip arthroplasty...
October 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28624340/effects-of-teriparatide-denosumab-or-both-on-spine-trabecular-microarchitecture-in-data-switch-a-randomized-controlled-trial
#20
Joy N Tsai, Linda A Jiang, Hang Lee, Didier Hans, Benjamin Z Leder
In postmenopausal women, 2 yr of combined teriparatide and denosumab increases bone mineral density more than either drug alone, and switching from either combination or teriparatide to denosumab for an additional 2 yr further increases bone mineral density. Conversely, switching from denosumab to teriparatide results in transient bone loss. The effects of these interventions on spine microarchitecture are unknown. In the DATA and DATA-Switch studies, 94 postmenopausal osteoporotic women were randomized to receive 24 mo of teriparatide (20 µg daily), denosumab (60 mg every 6 mo), or both...
October 2017: Journal of Clinical Densitometry
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