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Aging Male: the Official Journal of the International Society for the Study of the Aging Male

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https://www.readbyqxmd.com/read/29993302/effect-of-senescence-on-morphological-functional-and-oxidative-features-of-fresh-and-cryopreserved-canine-sperm
#1
Maíra Morales Brito, Daniel de Souza Ramos Angrimani, Bruno Rogério Rui, Giulia Kiyomi Vechiato Kawai, João Diego Agostini Losano, Camila Infantosi Vannucchi
The present research aimed to compare the hormonal profile, sperm quality and freezability of young and senile dogs. Dogs were assigned into Young Group (n = 11) and Senile Group (n = 11), additionally divided into Fresh Semen Group and Cryopreserved Semen Group. Males were evaluated for libido score and blood estrogen and testosterone assay. Sperm morphofunctional evaluations were performed based on Computer Assisted Sperm Analysis, morphology, mitochondrial activity, mitochondrial membrane potential, plasma and acrosomal membrane integrity, and DNA fragmentation...
July 11, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29985721/novel-symptom-questionnaire-for-the-differential-diagnosis-of-detrusor-underactivity-and-bladder-outlet-obstruction-in-men
#2
Aram Kim, Young-Jin Park, Kyung Ok Heo, Woo Suk Choi, Hyoung Keun Park, Sung Hyun Paick, Myung-Soo Choo, Hyeong Gon Kim
OBJECTIVE: To develop a questionnaire for the differential diagnosis of detrusor underactivity (DUA) and bladder outlet obstruction (BOO) without performing invasive pressure flow studies. STUDY DESIGN AND METHODS: Symptoms of men with DUA were analyzed and compared with those of men with BOO using eight questions from the developing questionnaire. Patients with DUA have a bladder contractility index (PdetQmax+5xQmax) less than 100, whereas those with BOO have a BOO index (PdetQmax-2xQmax) greater than 40 in urodynamic studies (UDS)...
July 9, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29950140/consequences-on-aging-process-and-human-wellness-of-generation-of-nitrogen-and-oxygen-species-during-strenuous-exercise
#3
Francesco Sessa, Giovanni Messina, Raffaele Russo, Monica Salerno, Carlo Castruccio Castracani, Alfio Distefano, Giovanni Li Volti, Aldo E Calogero, Rossella Cannarella, Laura M Mongioi', Rosita A Condorelli, Sandro La Vignera
Impairment of antioxidant defense system and increase in metabolic rate and production of reactive oxygen species have been demonstrated in strenuous exercise. Both at rest and during contractile activity, skeletal muscle generates a very complex set of reactive nitrogen and oxygen species; the main generated are superoxide and nitric oxide. The nature of the contractile activity influences the pattern and the magnitude of this reactive oxygen and nitrogen species (ROS) generation. The intracellular pro-oxidant/antioxidant homeostasis undergoes alteration owing to strenuous exercise and the major identified sources of intracellular free radical generation during physical activity are the mitochondrial electron transport chain, polymorphoneutrophil, and xanthine oxidase...
June 27, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29950136/life-quality-change-after-inflatable-penile-prosthesis-implantation
#4
Iyimser Ure, Ata Ozen, Cavit Can
PURPOSE: It was aimed to evaluate the changes in quality of life in patients with erectile dysfunction (ED) after inflatable penile prosthesis implantation. MATERIAL AND METHODS: Forty-one patients who underwent to an inflatable penile prosthesis implantation surgery due to ED were included in the study. The age of the patients, the indications for surgery, and the type of prosthesis implanted were recorded. All patients were implanted two-piece inflatable (AMS Ambicor™) or three-piece inflatable (AMS 700™) prostheses...
June 27, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29944060/the-effect-of-air-dust-pollution-on-semen-quality-and-sperm-parameters-among-infertile-men-in-west-of-iran
#5
Ali Najafpour, Faranak Aghaz, Shiva Roshankhah, Mitra Bakhtiari
BACKGROUND: Pollutants during haze and Asian dust storms are transported out of the Asian continent, affecting the regional climate and the hydrological and biogeochemical cycles. Nonetheless, no specific studies evaluated the dust particles influence on semen quality in a specific geographical area. OBJECTIVE: In this article, we investigated the effect of dust particles on semen quality and sperm parameters among infertile men. METHODS: A descriptive-analytic study was conducted among 850 infertile men between 2011 and 2015 years...
June 26, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29944055/evaluation-of-the-relationship-between-microalbuminuria-and-25-oh-vitamin-d-levels-in-patients-with-type-2-diabetes-mellitus
#6
Sema Ucak, Ecem Sevim, Damla Ersoy, Rıdvan Sivritepe, Okcan Basat, Sabri Atay
BACKGROUND: 25-(OH) vitamin D (VD) deficiency has been described as potential risk factor for the development of diabetes in many epidemiological studies. 25-(OH) VD deficiency and insulin resistance associated with this deficiency are common findings in patients with type 2 diabetes mellitus. The objective of this study is to evaluate the relationship between 25-(OH) VD levels and microalbuminuria. METHODS: The patients with type 2 diabetes mellitus aged between 40 and 65 years, who were admitted to the diabetes outpatient clinics of our hospital, were evaluated in two different groups...
June 26, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29925283/the-relationship-between-circulating-testosterone-and-inflammatory-cytokines-in-men
#7
Nur-Vaizura Mohamad, Sok Kuan Wong, Wan Nuraini Wan Hasan, James Jam Jolly, Mohd Fozi Nur-Farhana, Soelaiman Ima-Nirwana, Kok-Yong Chin
Testosterone is the predominant gonadal androgen in men. Low testosterone levels are found to be associated with an increased in metabolic risk and systematic inflammation. Since adipose tissue is a source of inflammatory cytokines, testosterone may regulate inflammation by acting on adipose tissue. This review aimed to explore the role of testosterone in inflammation and its mechanism of action. Both animal studies and human studies showed that (1) testosterone deficiency was associated with an increase in pro-inflammatory cytokines; (2) testosterone substitution reduced pro-inflammatory cytokines...
June 21, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29925274/analysis-of-cardiovascular-risk-factors-associated-with-serum-testosterone-levels-according-to-the-us-2011-2012-national-health-and-nutrition-examination-survey
#8
Chunhua Deng, Zhichao Zhang, Hongjun Li, Peng Bai, Xian Cao, Adrian Sandra Dobs
OBJECTIVE: To investigate associations between cardiovascular disease risk factors, including fasting glucose, cholesterol, high density lipoprotein cholesterol (HDL-c), LDL-c, blood pressure, body mass index (BMI), C-peptide, creatinine kinase, smoking, alcohol use, physical activity, C-reactive protein as well as homocysteine levels and cardiovascular events. METHODS: Data from 1545 men aged ≥40 years, with testosterone deficiency (TD) (<300 ng/dL) and non-TD (≥300 ng/dL) which were extracted from the National Health and Nutrition Examination Survey database 2011-2012 and analyzed...
June 20, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29921150/an-analysis-of-online-content-related-to-testosterone-supplementation
#9
Evan Sehn, Cassidy Mozak, Nese Yuksel, Cheryl A Sadowski
OBJECTIVE: To describe the quality of online information on testosterone replacement therapy (TRT) in men. METHODS: A quantitative content analysis was conducted on websites providing patient-directed information on TRT for the purpose of treating late onset hypogonadism (LOH). Websites were identified through Google in March 2017. The DISCERN instrument was used to determine the quality of health information. RESULTS: A total of 20 websites met inclusion criteria...
June 20, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29921153/prevalence-of-erectile-dysfunction-in-egyptian-males-with-metabolic-syndrome
#10
Mohammed Nader Salama, Ahmed Abulfotooh Eid, Alaa Hatem, Ahmed Kamal Swidan
OBJECTIVES: Determination of the potential effect of metabolic syndrome (MetS) on erectile function in Egyptian men and description of the sociodemographic characteristics of these men. MATERIALS AND METHODS: A cohort of 615 patients presenting to urology department aged between 30 and 75 years were prospectively assessed and divided into two groups. Group I (n = 325) diagnosed with MetS and mean age of 56.07 ± 8.51 years. Group II (n = 290) subjects with no MetS and mean age 54...
June 19, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29912660/high-serum-concentration-of-estradiol-may-be-a-risk-factor-of-prostate-enlargement-in-aging-male-in-china
#11
Ding Xu, Yu Wu, Haibo Shen, Subo Qian, Jun Qi
OBJECTIVE: Assess the association between serum sex hormone level and prostate volume in men with benign prostatic hyperplasia (BPH). MATERIAL AND METHODS: The study involved 239 BPH patients from January 2013 to June 2015 in our hospital. Each patient collected age, medical history, height, weight, body mass index, as well as a full examination of sex hormones, and transrectal ultrasound results. RESULTS: Estradiol (E2) was significantly associated with prostate volume (r = 0...
June 18, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29912597/cystatin-c-as-a-predictor-of-mortality-in-elderly-patients-with-chronic-kidney-disease
#12
Sebastjan Bevc, Nina Hojs, Maša Knehtl, Robert Ekart, Radovan Hojs
BACKGROUND: The prevalence of chronic kidney disease (CKD) in the elderly is high. Serum cystatin C is an accurate marker of kidney function and it also has prognostic utility in CKD patients. The aim of our study was to determine the prediction of serum cystatin C and other markers of kidney function on long-term survival in elderly CKD patients. METHODS: Fifty eight adult Caucasian patients, older than 65 years, without known malignancy, thyroid disease and/or not on steroid therapy were enrolled in the study...
June 18, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29901417/application-of-multivariate-longitudinal-models-in-sirt6-fbs-and-bmi-analysis-of-the-elderly
#13
Neda Gilani, Rouhollah Haghshenas, Mahmoud Esmaeili
OBJECTIVE: SIRT6 is a main regulator of metabolism and lifespan and its importance has been implicated in the prevention against aging-related diseases. The objective of this study was to examine the application of multivariate longitudinal models in SIRT6, FBS, and BMI analysis in the elderly men after eight weeks concurrent training with supplementation of l-arginine (l-Arg). METHODS: Thirty two elderly men with mean age of 63.09 ± 3.71 years were randomly divided into four equal-sized groups (each n = 8); Exercise + supplement (ES) group; exercise + placebo (EP) group; supplement (S) group and control (C) group...
June 14, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29863448/inverse-association-of-testosterone-and-sex-hormone-binding-globulin-levels-with-leukocyte-count-in-middle-aged-and-elderly-men
#14
Byoungjin Park, Yong-Jae Lee
OBJECTIVE: The inverse associations of testosterone and sex hormone-binding globulin (SHBG) levels with cardiometabolic diseases are well established and are increasingly viewed as inflammatory diseases. This study aimed to examine the associations of testosterone and SHBG levels with leukocyte count in 451 Korean men aged ≥50 years. METHODS: Serum testosterone and SHBG levels were categorized into tertiles. High leukocyte count was defined as ≥7340 cells/μl, which corresponded to the 75th percentile of the current sample...
June 4, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29863438/aging-male-symptomatology-and-eating-behavior
#15
Kai K Kummer, Harrison G Pope, James I Hudson, Georg Kemmler, Germar-Michael Pinggera, Barbara Mangweth-Matzek
OBJECTIVE: The literature on eating disorders in older males is still very limited. We assessed the relationship between aging male symptomatology and eating behavior in middle-aged and older men. METHOD: We distributed anonymous questionnaires to men aged 40-75 years living in or near Innsbruck, Austria, covering demographic items, current eating disorder symptoms (as defined by DSM-5), and associated measures of eating pathology, body image, and sports activity (including exercise addiction)...
June 4, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29863428/effect-of-cigarette-smoking-on-sexual-functions-psychological-factors-and-disease-activity-in-male-patients-with-ankylosing-spondylitis
#16
İlknur Aykurt Karlıbel, Seyhan Dülger, Meliha Kasapoğlu Aksoy, Muhammet Güzelsoy, Ali Rıza Türkoğlu, Lale Altan, Tekin Yıldız
OBJECTIVE: This study aims to investigate the effect of smoking on sexual functions in AS patients. PATIENTS AND METHODS: A total of 67 male AS patients with a median age of 34 years (range: 18-57) reporting sexual activity at least for the past 4 weeks period were included. Patients were divided into smokers (Group 1, n = 47) and non-smokers (Group 2, n = 20). Fagerström test for nicotine dependence, smoking history, exhaled carbon monoxide test were recorded for smoking AS patients...
June 4, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29856246/chronic-cacha%C3%A3-a-consumption-affects-the-structure-of-tibial-bone-by-decreasing-bone-density-and-density-of-mature-collagen-fibers-in-middle-aged-wistar-rats
#17
José Renato Romero, Walter Krause Neto, Alexandre Sabbag da Silva, Everton Luiz Dos Santos, Marco Aurélio Added, Eduardo Pianca, Eliane Florencio Gama, Romeu Rodrigues de Souza
Several studies have demonstrated that alcohol consumption can decrease bone density and alter its structure. However, most of the studies did not investigate the effects of specific alcoholic beverages. This study determined the effects of chronic consumption of cachaça (a Brazilian beverage containing alcohol) on body weight (BW), tibia bone density and on the tibia collagen density in middle-aged Wistar rats. Rats with 9 months old were submitted for 100 days, to a liquid diet of cachaça diluted in water with a progressive and controlled concentration (10°GL, 15°GL, 20°GL, 25°GL, and 30°GL)...
June 1, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29768978/levels-of-serum-trace-elements-in-patients-with-peyronie
#18
Mustafa Gunes, Rahmi Aslan, Recep Eryılmaz, Halit Demir, Kerem Taken
AIM: The etiology of the disease of Peyronie is not certainly known. However, penile micro traumas are thought to be important in the pathogenesis of Peyronie's disease (PD) in genetically predisposed individuals. In this study, we aimed to determine the relationship of some trace element and heavy metals with PD. MATERIAL AND METHODS: Thirty Peyronie patients and 26 healthy volunteers were included in the study. In individuals in both groups, levels of serum trace elements (Manganese [Mn], Cu, Cobalt (Co), zinc [Zn], Cd, and iron [Fe]) were determined separately by Atomic Absorption Spectrophotometer method in Yüzüncü Yıl University Central Research Laboratory...
May 17, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29734846/the-efficacy-and-safety-of-short-acting-testosterone-ointment-glowmin-for-late-onset-hypogonadism-in-accordance-with-testosterone-circadian-rhythm
#19
Toshiyasu Amano, Teruaki Iwamoto, Yoshikazu Sato, Tetsuya Imao, Carolyn Earle
INTRODUCTION: It is well known that there is a reduction of circadian rhythm in blood testosterone levels with aging. Our previous report revealed that 3 mg of short-acting testosterone ointment (Glowmin: GL) elevated serum testosterone levels to within the physiological range for 4-6 h. The aim of this study was to clarify the clinical efficacy and safety of GL used topically once every morning, to enhance the circadian rhythm of testosterone, for late-onset hypogonadism (LOH). METHODS: A total of 61 LOH patients received 3 mg of GL topically once a day in the morning on scrotal skin for 24 weeks...
May 8, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29730957/homeostasis-apoptosis-and-cell-cycle-in-normal-and-pathological-prostate
#20
Norelia Torrealba, Gonzalo Rodríguez-Berriguete, Raúl Vera, Benito Fraile, Gabriel Olmedilla, Pilar Martínez-Onsurbe, Manuel Sánchez-Chapado, Ricardo Paniagua, Mar Royuela
Prostatic diseases such as hyperplasia and cancer are a consequence of glandular aging due to the loss of homeostasis. Glandular homeostasis is guaranteed by the delicate balance between production and cell death. Both cell renewal and apoptosis are part of this delicate balance. We will explore the predictive capacity for biochemical progression, following prostatectomy, of some members of the Bcl-2 family and of proteins involved in cell cycle inhibition in conjunction with established classical markers. The expression of Bcl-2, Bcl-xL, Mcl-1, Bax, Bim, Bad, PUMA, Noxa, p21, p27, Rb and p53 were analyzed by immunochemistry in 86 samples of radical prostatectomy and correlated with each of the markers established clinicopathological tests using statistical tests such as Sperman, Kaplan-Meier curves, unifactorial Cox, and multifactorial...
May 6, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
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