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Aging Male: the Official Journal of the International Society for the Study of the Aging Male

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https://www.readbyqxmd.com/read/29168426/interleukin-18-and-testosterone-levels-in-men-with-metabolic-syndrome
#1
Petya Angelova, Zdravko Kamenov, Adelina Tsakova, Yosif El-Darawish, Haruki Okamura
OBJECTIVE: Interleukin 18 (IL-18) is an adipokine associated with obesity. Data about the relationship of IL-18 to the metabolic syndrome (MS) are still scarce. Low testosterone (T) levels are common in men with MS, but we did not find data about the levels of IL-18 in men with low T. The aim of this study was to determine the levels of IL-18 in men with MS with or without low T. PATIENTS AND METHODS: A total of 251 men were included in the study. Of them 218 had MS (IDF 2005) and they were divided according to their morning total testosterone (TT) level (cutoff 10...
November 23, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29166824/increased-visceral-adiposity-index-associated-with-sexual-dysfunction-in-men
#2
Murat Dursun, Huseyin Besiroglu, Suleyman Sami Cakir, Alper Otunctemur, Emin Ozbek
OBJECTIVE: Visceral adipose index (VAI) is a novel parameter for the evaluation of visceral obesity. As we know that obesity is a risk factor for erectile dysfunction (ED). So, in this study, we compared the VAI levels between the men with ED and without ED. MATERIALS AND METHOD: A total of 177 men were included in the study. Ninety-five men with ED and 82 men without ED (control). All men were evaluated for ED by Index of Erectile Function-5 items (IIEF-5). VAI levels were calculated using body mass index, high density lipoprotein and tryglyceride levels...
November 22, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29157088/examining-the-effect-of-the-computer-based-educational-package-on-quality-of-life-and-severity-of-hypogonadism-symptoms-in-males
#3
Elahe Afsharnia, Minoo Pakgohar, Shahla Khosravi, Hamid Haghani
OBJECTIVE: The objective of this study was to determine the effect of the computer-based educational package on men's QoL and the severity of their hypogonadism symptoms. METHODS: A quasi-experimental study was conducted on 80 male employees. The data collection tool included the 'Aging Male Symptoms' (AMS) and 'Short Form-36' (SF36) questionnaires. Four sessions were held for the intervention group over a period of 4 weeks. Two months after training, QoL and the severity of hypogonadism symptoms were measured in both the intervention and control groups...
November 20, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29157083/folate-a-possible-role-in-erectile-dysfunction
#4
Massimiliano Sansone, Andrea Sansone, Mariagrazia Romano, Silvia Seraceno, Luigi Di Luigi, Francesco Romanelli
A growing body of evidence suggests a role for homocysteine (Hcys) and folate (FA) in erectile function (EF): Hcys appears to impair EF affecting endothelium via several mechanism whereas the role of FA remains to be elucidated, besides decreasing Hcys. To assess correlation between erectile dysfunction (ED) and serum levels of FA, Hcys, and B12, we enrolled 31 patients affected by ED (Group A; age 52.83 ± 11.89 years) and 31 healthy adults (Group B; age 49.14 ± 13.63 years). Fasting blood samples were taken for each subject...
November 20, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29129118/gene-expression-of-insulin-receptor-insulin-like-growth-factor-increases-and-insulin-like-growth-factor-binding-protein-3-reduces-with-increase-in-prostate-size-in-benign-prostatic-hyperplasia
#5
Karli Sreenivasulu, Hanumanthappa Nandeesha, Lalgudi Narayanan Dorairajan, Medha Rajappa, Vickneshwaran Vinayagam, Cleetus Cherupanakkal
INTRODUCTION: Although the role of insulin in the development of benign prostatic hyperplasia (BPH) is well established, there are no studies regarding alteration in the gene expression of components of insulin-signaling pathway and their association with prostate size in BPH. Hence, the study was designed to analyze the gene and protein expression of insulin receptor and its related components in patients with BPH. MATERIALS AND METHODS: Twenty-seven BPH patients aged between 55 and 75 years were recruited in the study and prostatic tissues were obtained after transurethral resection of the prostate...
November 12, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29113548/cognitive-functions-and-health-related-quality-of-life-in-men-with-benign-prostatic-hyperplasia-and-symptoms-of-overactive-bladder-when-treated-with-a-combination-of-tamsulosin-and-solifenacin-in-a-higher-dosage
#6
Kirill Kosilov, Irina Kuzina, Vladimir Kuznetsov, Yuliya Gainullina, Liliya Kosilova, Alexandra Prokofyeva, Sergey Loparev
AIM: To study the cognitive functions and health-related quality of life (HRQoL) in individuals taking a combination of tamsulosin and solifenacin in a higher dosage. METHODS: All patients (n = 262) were assigned to group A (N = 93, tamsulosin 0.4 mg + solifenacin 10 mg per day), group B (N = 83, tamsulosin 0.4 mg + solifenacin 20 mg), and control group C (N = 86; tamsulosin 0.4 mg + placebo). The lower urinary tract (LUT) condition was assessed on the scales International Prostate Symptom Score, Over Active Bladder Awareness Tool and uroflowmetry...
November 7, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28984502/the-association-between-hypogonadism-symptoms-with-serum-testosterone-fsh-and-lh-in-men
#7
Forough Samipoor, Sedigheh Pakseresht, Parvaneh Rezasoltani, Mojtaba Mehrdad
OBJECTIVES: This study aimed to determine the relationship of hypogonadism symptoms with the levels of sex hormones in men. METHODS: This cross-sectional study was conducted on 140 men aged above 40 years. Data collections were conducted by Aging Male Scales (AMS) questionnaire and some sociodemographic variables. Then, 3 ml blood serum was sampled for testosterone (free and total), FSH and LH. Data were analyzed by descriptive and analytical statistics. RESULTS: Mean age score was 52...
October 6, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28944704/the-relationship-between-vitamin-d-level-and-erectile-dysfunction-in-patients-with-type-2-diabetes-mellitus
#8
Sema Basat, Rıdvan Sivritepe, Damla Ortaboz, Ecem Sevim Çalık, Eyüp Veli Küçük, Berkan Şimşek, Sabri Atay, Arzu Çalışgan
Recent studies have suggested that a relationship could exist between 25-hydroxyvitamin D [25(OH)D] deficiency and erectile dysfunction (ED). The present study evaluated the relationship between 25(OH)D levels and ED in male patients with type 2 diabetes mellitus (DM). The study included 98 patients with type 2 DM aged between 18-80 years. The International Index of Erectile Function (IIEF-5) Questionnaire was administered. The patients were divided into three groups according to IIEF-5 scoring: IIEF-5 score between 5-10, severe ED; IIEF-5 score between 11-20, moderate ED; IIEF-5 score between 21-25, no ED...
September 23, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28937309/metabolic-and-hormonal-responses-to-different-resistance-training-systems-in-elderly-men
#9
Marcos R Paunksnis, Alexandre L Evangelista, Cauê V La Scala Teixeira, Gustavo Alegretti João, Rafael M Pitta, Angelica C Alonso, Aylton Figueira, Andrey Jorge Serra, Julien S Baker, Brad Jon Schoenfeld, Danilo S Bocalini
OBJECTIVE: To compare acute and sub-acute responses in hormonal profile and metabolic parameters in elderly people who participated in two methods of strength training (ST) with equalized loads. METHODS AND MATERIALS: A total of 12 elder individuals (65 ± 3 years) were randomly assigned to two training methods: constant intensity (CI, 3 sets of 10 repetitions with 75% of 1RM) and variable intensity (VI, 1st set: 12 repetitions at 67% of 1RM > 2nd set: 10 repetitions at 75% of 1RM and 3rd set: 8 repetitions at 80% of 1RM)...
September 22, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28929838/the-influence-of-nutritional-factors-on-prostate-cancer-incidence-and-aggressiveness
#10
Manrique Pascual-Geler, Noelia Urquiza-Salvat, Jose Manuel Cozar, Inmaculada Robles-Fernandez, Ana Rivas, Luis Javier Martinez-Gonzalez, Francisco Manuel Ocaña-Peinado, Jose Antonio Lorente, Maria Jesus Alvarez-Cubero
There is an increasing evidence for a link between nutrition, lifestyle and prostate cancer (PCa) development and/or progression of disease. The objective of this study was to examine the association between dietary factors and PCa incidence and aggressiveness in a case-control study. After the analysis of the anatomic pathology, subjects were classified in patients with PCa (n = 157) and controls (n = 158). Clinical data including Gleason score, PSA values and biopsy results, were compiled. Frequencies of food consumption and sociodemographic data were also obtained...
September 20, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28920756/sleep-disturbance-as-a-clinical-sign-for-severe-hypogonadism-efficacy-of-testosterone-replacement-therapy-on-sleep-disturbance-among-hypogonadal-men-without-obstructive-sleep-apnea
#11
Kazuyoshi Shigehara, Hiroyuki Konaka, Kazuhiro Sugimoto, Takahiro Nohara, Koji Izumi, Yoshifumi Kadono, Mikio Namiki, Atsushi Mizokami
OBJECTIVE: The present subanalysis of the EARTH study investigates the effects of one year testosterone replacement therapy (TRT) on sleep disturbance among hypogonadal men without obstructive sleep apnea. METHODS: Sleep disturbance was defined as three or more points in question 4 of the aging males symptoms (AMS) questionnaire. All participants completed the AMS scale, International Prostatic Symptoms Score (IPSS), Sexual Health Inventory for Men (SHIM) and Short Form 36 (SF-36) health survey at baseline and after 12 months...
September 18, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28956684/correction-to-wolf-et-al-effectiveness-and-tolerability-of-parenteral-testosterone-undecanoate-a-post-marketing-surveillance-study
#12
(no author information available yet)
No abstract text is available yet for this article.
December 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28812471/effectiveness-and-tolerability-of-parenteral-testosterone-undecanoate-a-post-marketing-surveillance-study
#13
Jan Wolf, Dieter Keipert, Heiko Motazedi, Michael Ernst, Joanne Nettleship, Louis Gooren
This observational post-marketing study of parenteral testosterone undecanoate (TU) in a non-selected population aimed to: examine the effectiveness of TU as treatment of hypogonadism; record adverse drug reactions (ADR) quantitatively particularly regarding polycythemia, prostate safety and cardiovascular-related metabolic risk factors; and verify whether recommended injection intervals apply to routine clinical practice. Eight hundred and seventy subjects from 259 outpatient units scheduled to visit the clinic six times were included...
December 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28787260/genetic-variants-in-5p13-2-and-7q21-1-are-associated-with-treatment-for-benign-prostatic-hyperplasia-with-the-%C3%AE-adrenergic-receptor-antagonist
#14
Xiaoqiang Qian, Ding Xu, Hailong Liu, Xiaoling Lin, Yongjiang Yu, Jian Kang, Xujun Sheng, Jianfeng Xu, Siqun Zheng, Danfeng Xu, Jun Qi
BACKGROUND: The etiology of benign prostatic hyperplasia (BPH) has not been well established. The preferred medical treatment for many men with symptomatic benign prostatic hyperplasia is either an α-adrenergic receptor antagonist (α-blocker), or a 5α-reductase inhibitor. Single nucleotide polymorphism (SNP) is a powerful tool for successful implementation of individualized treatment. METHODS: Eighteen SNPs associated with drug efficacy in a Chinese population were genotyped in 790 BPH cases (330 aggressive and 460 non-aggressive BPH cases) and 1008 controls...
December 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28787255/use-of-the-international-prostate-symptom-score-ipss-in-chinese-male-patients-with-benign-prostatic-hyperplasia
#15
Carlos King-Ho Wong, Edmond Pui-Hang Choi, Steve Wai-Hee Chan, James Hok-Leung Tsu, Chi-Wai Fan, Peggy Sau-Kwan Chu, Fu-Keung Cheung, Wai-Kit Ma, Ida Soo Fan Mah, Sidney Kam-Hung Yip, Simon See-Ming Hou, Hing-Shing So, CindyLo-Kuen Lam
PURPOSE: To test the psychometric properties of the International Prostate Symptom Score (Hong Kong Chinese version 2) (IPSS) in Chinese male patients with benign prostatic hyperplasia (BPH) under secondary care. METHODS: A prospective longitudinal study was done by interviewing subjects at baseline, at 2 week after baseline for assessing test-retest reliability and at 26 week after baseline for assessing responsiveness. All subjects were interviewed to complete a structured questionnaire including IPSS, Short Form-12 Health Survey version 2 (SF-12v2) and Depression Anxiety Stress Scale (DASS)...
December 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28787230/patient-perceived-effectiveness-and-impact-on-quality-of-life-of-solifenacin-in-combination-with-an-%C3%AE-blocker-in-men-with-overactive-bladder-in-sweden-a-non-interventional-study
#16
Lars Henningsohn, Suzanne Kilany, Maja Svensson, Judith L Jacobsen
Treating male lower urinary tract symptoms (LUTS) by targeting the prostate would have limited effect on overactive bladder (OAB) symptoms. This study assessed perceived symptoms and quality of life (QoL) of male patients with OAB treated with an α-blocker plus solifenacin in daily clinical practice. Male patients aged ≥40 years were included after the decision was made to initiate treatment with an α-blocker for LUTS plus solifenacin for OAB symptoms. The primary endpoint was change in patient perception of bladder condition (PPBC) questionnaire score over 6 months...
December 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28780904/the-impact-of-age-bmi-and-sex-hormone-on-aging-males-symptoms-and-the-international-index-of-erectile-function-scores
#17
Xiao-Hua Yu, Jing Zhao, Shu-Cheng Zhang, Jian-Hui Li, Jun-Biao Zheng, Zheng Li, Guo-Qing Liang, Hui-Juan Shi, Wei-Jin Zhou, Qian-Xi Zhu
OBJECTIVE: To analyze the impact of age, BMI and sex hormone on aging males' symptoms (AMS) and the 5-item version of the international index of erectile function (IIEF-5) scores in middle-aged and elderly Chinese men. METHODS: A population-based cross-sectional study was conducted in Jiashan County. A total of 969 men, aged between 40 and 80 years old, were admitted. Physical examination and the sex hormones were measured, and AMS and IIEF-5 scores were assessed...
December 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28696825/androgen-status-in-non-diabetic-elderly-men-with-heart-failure
#18
Goran Loncar, Biljana Bozic, Aleksandar N Neskovic, Natasa Cvetinovic, Mitja Lainscak, Nenad Prodanovic, Hans-Dirk Dungen, Stephan von Haehling, Zoran Radojicic, Tobias Trippel, Biljana Putnikovic, Natasa Markovic-Nikolic, Vera Popovic
PURPOSE: We aimed at evaluating androgen status (serum testosterone [TT] and estimated free testosterone [eFT]) and its determinants in non-diabetic elderly men with heart failure (HF). Additionally, we investigated its associations with body composition and long-term survival. METHODS: Seventy three non-diabetic men with HF and 20 healthy men aged over 55 years were studied. Echocardiography, 6-min walk test, grip strength, body composition measurement by DEXA method were performed...
December 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28414247/preoperative-sexual-status-of-japanese-localized-prostate-cancer-patients-comparison-of-sexual-activity-and-epic-scores
#19
Hisanori Taniguchi, Hidefumi Kinoshita, Yuya Koito, Masaaki Yanishi, Makoto Taguchi, Takao Mishima, Kenji Yoshida, Yoshihiro Komai, Kaneki Yasuda, Masato Watanabe, Motohiko Sugi, Tadashi Matsuda
OBJECTIVE: This study aimed to evaluate the relationship between sexual activity and sexual function using questionnaires distributed to middle-aged Japanese patients with localized prostate cancer. METHODS: A total of 145 patients who underwent radical prostatectomy were enrolled in the survey reported on herein. Sexual activity and sexual function were investigated via the Expanded Prostate Cancer Index Composite (EPIC) and an original self-reported questionnaire...
December 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28332895/comorbidities-as-predictors-of-incidental-prostate-cancer-after-holmium-laser-enucleation-of-the-prostate-diabetes-and-high-risk-cancer
#20
Kazuhiro Ohwaki, Fumiyasu Endo, Masaki Shimbo, Akiko Fujisaki, Kazunori Hattori
Prostate cancer can be diagnosed as an incidental finding during the pathological examination of benign prostatic hyperplasia (BPH) specimens by Holmium laser enucleation of the prostate (HoLEP). BPH and comorbidities such as hypertension, diabetes, and dyslipidemia often coexist in elderly people. We identified which comorbidities can be used to predict the presence of incidental prostate cancer, particularly high-risk cancer, in men who had undergone HoLEP. On the basis of pathological findings of HoLEP specimens, patients with incidental cancer were categorized as low-risk (Gleason ≤6 and T1a) or high-risk (all others)...
December 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
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