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Aging Male: the Official Journal of the International Society for the Study of the Aging Male

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https://www.readbyqxmd.com/read/28084147/early-weight-loss-predicts-the-reduction-of-obesity-in-men-with-erectile-dysfunction-and-hypogonadism-undergoing-long-term-testosterone-replacement-therapy
#1
Mahmoud Salman, Dany-Jan Yassin, Huda Shoukfeh, Joanne Elisabeth Nettleship, Aksam Yassin
We and others have previously shown that testosterone replacement therapy (TRT) results in sustained weight loss in the majority of middle-aged hypogonadal men. Previously, however, a small proportion failed to lose at least 5% of their baseline weight. The reason for this is not yet understood. In the present study, we sought to identify early indicators that may predict successful long-term weight loss, defined as a reduction of at least 5% of total body weight relative to baseline weight (T0), in men with hypogonadism undergoing TRT...
January 13, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28084142/the-role-of-sex-steroid-hormones-in-benign-prostatic-hyperplasia
#2
Bernice Asiedu, Yvonne Anang, Adraina Nyarko, Derek Amartey Doku, Brodrick Y Amoah, Sheila Santa, Robert A Ngala, George A Asare
INTRODUCTION: The etiology of benign prostatic hyperplasia (BPH) remains a mystery to scientists; estrogen/androgen imbalance in aged men has been implicated. METHODS: Thirty (30) apparently healthy men and newly diagnosed BPH patients were recruited from the Ghana Police Hospital. Lower urinary tract syndrome (LUTS) and prostate volume were assessed via the prostate symptom score sheet (IPSS) and abdominopelvic scan, respectively. Laboratory assays for total prostate specific antigen (tPSA) and hormones [androstenedione (AED), testosterone (T), dihydrotestosterone (DHT), androstanedioladiol (3α-adiol), androstanediol (3β-diol), estrone (E1) and estradiol (E2)] were performed via ELISA techniques...
January 13, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28084133/use-of-geriatric-assessment-and-screening-tools-of-frailty-in-elderly-patients-with-prostate-cancer-review
#3
Maria-José Molina-Garrido, Carmen Guillén-Ponce
The management of prostate cancer in the elderly is a major public health concern in most countries. Currently, most prostate cancers are diagnosed in elderly males. The elderly population is very heterogeneous. Thus, the current challenge is to identify better those individuals for whom specific screening tools and a Comprehensive Geriatric Assessment (CGA) would be beneficial. On the basis of the recommendations of the Prostate Cancer Working Group in the International Society of Geriatric Oncology, older patients with prostate cancer should be managed according to their individual health status and not by their age...
January 13, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28074679/vitamin-d-treatment-improves-levels-of-sexual-hormones-metabolic-parameters-and-erectile-function-in-middle-aged-vitamin-d-deficient-men
#4
Onder Canguven, Raidh A Talib, Walid El Ansari, Dany-Jan Yassin, Abdullah Al Naimi
BACKGROUND: The associations between serum vitamin D (VD), serum testosterone (TT) and metabolic syndrome are complex and with limited published research, particularly on the effects of VD treatment on sexual hormones, erectile function and the metabolic syndrome. OBJECTIVES: This study assessed whether a monthly high dose VD treatment for 12 months in VD deficient middle-aged men was associated with: changes in levels of sexual hormones, improvement of diabetes control and metabolic syndrome components, better erectile function [International Index of Erectile Function (IIEF)-5 questionnaire]; and changes in a prostate marker...
January 11, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28074677/the-effective-tool-for-self-assessment-of-adherence-to-treatment-in-patients-with-benign-prostatic-obstruction-and-overactive-bladder-symptoms
#5
Kirill Kosilov, Sergey Loparev, Irina Kuzina, Olga Shakirova, Natalya Zhuravskaya, Alexandra Lobodenko
PURPOSE: Study of validity of the Medication Adherence Self-Report Inventory (MASRI) for use in clinical practice to treat patients with benign prostatic obstruction (BPO) accompanied with overactive bladder (OAB) symptoms. METHODS: During 12 weeks of the randomized study, 452 patients with BPO and OAB symptoms (mean age of 61.3 (12.7)) were studied for adherence to the treatment with Tamsulosin, Solifenacin and Trospium using the MASRI. External monitoring instruments included the Brief Medication Questionnaire (BMQ) and the visual remaining pill count...
January 11, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28067607/hormone-therapy-for-prostate-cancer-increases-the-risk-of-alzheimer-s-disease-a-nationwide-4-year-longitudinal-cohort-study
#6
Jhen-Hao Jhan, Yuan-Han Yang, Yu-Han Chang, Shiao-Jin Guu, Chia-Chun Tsai
INTRODUCTION: Androgen-deprivation therapy (ADT) is recognized to be the preferred first-line treatment for advanced prostate cancer. However, the risk-benefit ratio of ADT remains poorly defined and the relationship between androgen depletion and dementia is not clear. AIM: To investigate the risk of developing Alzheimer's disease (AD) in patients undergoing ADT for prostate cancer. METHODS: Data from 24 360 prostate cancer patients were collected from the Longitudinal Health Insurance Database of Taiwan...
January 9, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28067604/central-hypogonadism-due-to-a-giant-silent-fsh-secreting-atypical-pituitary-adenoma-effects-of-adenoma-dissection-and-short-term-leydig-cell-stimulation-by-luteinizing-hormone-lh-and-human-chorionic-gonadotropin-hcg
#7
Daniele Santi, Giorgia Spaggiari, Livio Casarini, Flaminia Fanelli, Marco Mezzullo, Uberto Pagotto, Antonio R M Granata, Cesare Carani, Manuela Simoni
We present a case report of an atypical giant pituitary adenoma secreting follicle-stimulating hormone (FSH). A 55-year-old patient presented for erectile dysfunction, loss of libido and fatigue. The biochemical evaluation showed very high FSH serum levels in the presence of central hypogonadism. Neither testicular enlargement nor increased sperm count was observed, thus a secretion of FSH with reduced biological activity was supposed. The histological examination after neuro-surgery showed an atypical pituitary adenoma with FSH-positive cells...
January 9, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28042739/high-intensity-interval-training-hiit-increases-insulin-like-growth-factor-i-igf-i-in-sedentary-aging-men-but-not-masters-athletes-an-observational-study
#8
Peter Herbert, Lawrence D Hayes, Nicholas Sculthorpe, Fergal M Grace
INTRODUCTION: The aim of this investigation was to examine the impact high-intensity interval training (HIIT) on serum insulin-like growth factor-I (IGF-I) in active compared with sedentary aging men. METHODS: 22 lifetime sedentary (SED; 62 ± 2 years) and 17 masters' athletes (LEX; 60 ± 5 years) were recruited to the study. As HIIT requires preconditioning exercise in sedentary cohorts, the study required three assessment phases; enrollment (phase A), following preconditioning exercise (phase B), and post-HIIT (phase C)...
December 31, 2016: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/27960590/use-of-thermobalancing-therapy-in-ageing-male-with-benign-prostatic-hyperplasia-with-a-focus-on-etiology-and-pathophysiology
#9
Simon Allen, Ivan Aghajanyan
INTRODUCTION: We investigated if "thermobalancing" therapy (TT), using Dr Allen's therapeutic device (DATD) in men with benign prostatic hyperplasia (BPH), can aid in understanding the etiology and pathophysiology of BPH. METHODS: We compared urinary and other parameters of BPH patients who received TT over 6 months (treatment group) with those of healthy volunteers who had not received the treatment (control group). Dynamics of symptoms and indicators in each group were evaluated in comparison with their data at the beginning and end of the study...
December 14, 2016: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/27929734/assessment-of-the-validity-and-reliability-of-a-questionnaire-on-knowledge-and-attitude-of-general-practitioners-about-andropause
#10
Maliheh Abootalebi, Marzieh Kargar, Alireza Aminsharifi
BACKGROUND AND OBJECTIVE: Andropause is one of the clinical and biochemical syndromes in aging men associated with the decrease in serum testosterone levels. With the increase in aging male population, life span in Iran, and focus on quality of life, andropause will become a major health issue that needs to be addressed in order to prevent disability. General practitioners, as the first level of health care providers, are in the best position to assess their knowledge and attitude about andropause period, so a structured instrument is necessary to assess them...
December 8, 2016: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/27879154/20-years-since-the-international-society-of-the-ageing-male-issam-was-founded
#11
Bruno Lunenfeld
No abstract text is available yet for this article.
December 2016: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/27876434/testosterone-estradiol-ratio-is-it-useful-in-the-diagnosis-of-erectile-dysfunction-and-low-sexual-desire
#12
A M Castelló-Porcar, J M Martínez-Jabaloyas
Erectile dysfunction and low sexual desire are multifactorial diseases. The decrease in testosterone levels is one of the causes, but the effect of estradiol is not well known. Moreover, study has shown that the testosterone/estradiol ratio has more influence over sexuality than does estradiol alone. The aim of the study was to determine whether the balance between testosterone and estradiol has any relation to some aspects of sexual function. It was an ambispective study of 230 patients with urological problems unrelated to sexuality...
December 2016: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/27873548/a-reliability-generalization-meta-analysis-of-coefficient-alpha-and-test-retest-coefficient-for-the-aging-males-symptoms-ams-scale
#13
Chin-Pang Lee, Yu-Wen Chiu, Chun-Lin Chu, Yu Chen, Kun-Hao Jiang, Jiun-Liang Chen, Ching-Yen Chen
PURPOSE: The aging males' symptoms (AMS) scale is an instrument used to determine the health-related quality of life in adult and elderly men. The purpose of this study was to synthesize internal consistency (Cronbach's alpha) and test-retest reliability for the AMS scale and its three subscales. METHODS: Of the 123 studies reviewed, 12 provided alpha coefficients which were then used in the meta-analyses of internal consistency. Seven of the 12 included studies provided test-retest coefficients, and these were used in the meta-analyses of test-retest reliability...
December 2016: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/27841078/the-correlation-between-highly-sensitive-c-reactive-protein-levels-and-erectile-function-among-men-with-late-onset-hypogonadism
#14
Kazuyoshi Shigehara, Hiroyuki Konaka, Masashi Ijima, Takahiro Nohara, Kazutaka Narimoto, Koji Izumi, Yoshifumi Kadono, Yasuhide Kitagawa, Atsushi Mizokami, Mikio Namiki
We investigated the correlation between highly sensitive C-reactive protein (hs-CRP) levels and erectile function, and assessed the clinical role of hs-CRP levels in men with late-onset hypogonadism (LOH) syndrome. For 77 participants, we assessed Sexual Health Inventory for men (SHIM) score, Aging Male Symptoms (AMS) score and International Prostate Symptom Score (IPSS). We also evaluated free testosterone (FT), hs-CRP, total cholesterol, triglyceride levels, high density lipoprotein cholesterol, hemoglobin A1c, body mass index, waist size and blood pressure...
December 2016: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/27750487/the-relationship-between-serum-total-testosterone-and-free-testosterone-levels-with-serum-hemoglobin-and-hematocrit-levels-a-study-in-1221-men
#15
Yu Seob Shin, Jae Hyung You, Jai Seong Cha, Jong Kwan Park
OBJECTIVE: To investigate the relationship between serum total testosterone (TT) and free testosterone (FT) levels in men with anemia. METHODS: We reviewed the records of 1221 subjects between March 2009 and December 2014. All the subjects' blood samples were drawn for TT and FT assays. Their serum hemoglobin (Hb) and serum hematocrit (Hct) levels were measured. The primary objective of our study was to investigate the association between TT and FT levels with Hb and Hct levels...
December 2016: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/27690744/rigiscan-data-under-long-term-testosterone-therapy-improving-long-term-blood-circulation-of-penile-arteries-penile-length-and-girth-erectile-function-and-nocturnal-penile-tumescence-and-duration
#16
Onder Canguven, Raidh A Talib, Walid El-Ansari, Ahmed Shamsoddini, Mahmoud Salman, Abdulla Al-Ansari
BACKGROUND: Late-onset hypogonadism (LOH) presents with low serum testosterone (TT) levels and sexual and nonsexual symptoms. Erectile dysfunction affects a man's self-esteem and as a result partner relationship and quality of life. OBJECTIVES: To investigate the andrological clinical profile outcomes of testosterone therapy (TTh) in men (n = 88) with symptomatic LOH complaints and symptoms. MAIN OUTCOME MEASURES: Erectile function was assessed using the International Index of Erectile Function-5 questionnaire at baseline and at 6 and 12 months of TTh...
December 2016: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/27690723/the-relationship-between-occupational-status-biological-condition-and-androgen-hormone-level-among-polish-adult-men-the-wroclaw-male-study
#17
Monika Łopuszańska-Dawid, Alicja Szklarska, Halina Kołodziej, Anna Lipowicz, Ewa A Jankowska
Population health and its determinants are one of the major challenges to social and economic policy. The aim of this study was to investigate the relationship between occupational activity and biological condition in adult working Polish men. The participants of the study were 300 men (30-65 years), healthy inhabitants of the city of Wroclaw, Poland. Seventeen measures of biological condition were examined. The subjects were divided into three different occupational groups: professionals, soldiers and skilled workers...
December 2016: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/27650467/could-gonadal-and-adrenal-androgen-deficiencies-contribute-to-the-depressive-symptoms-in-men-with-systolic-heart-failure
#18
Katarzyna Kulej-Lyko, Jacek Majda, Stephan von Haehling, Wolfram Doehner, Monika Lopuszanska, Alicja Szklarska, Waldemar Banasiak, Stefan D Anker, Piotr Ponikowski, Ewa A Jankowska
BACKGROUND: Testosterone (TT) and dehydroepiandrosterone sulphate (DHEAS) are neurosteroids and their deficiencies constitute the hormone risk factors promoting the development of depression in elderly otherwise healthy men. We investigated the link between hypogonadism and depression in accordance with age and concomitant diseases in men with systolic HF using the novel scale previously dedicated for elderly population. METHODS: We analysed the prevalence of depression and severity of depressive symptoms in population of 226 men with systolic HF (40-80 years) compared to 379 healthy peers...
December 2016: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/27841074/older-age-and-a-higher-ehra-score-allow-higher-levels-of-frailty-syndrome-to-be-predicted-in-patients-with-atrial-fibrillation
#19
Agnieszka Mlynarska, Rafal Mlynarski, Krzysztof S Golba
BACKGROUND: There is no research that evaluates the relationship between the severity of the symptoms of atrial fibrillation (AF), the presence of frailty syndrome and acceptance of the illness. METHODS: The study included 132 patients aged 72.7 ± 6.73 with diagnosed AF. The severity of the symptoms of AF was determined according to European Heart Rhythm Association (EHRA) guidelines, frailty syndrome was assessed using the Tilburg frailty indicator (TFI) and the acceptance of the illness was assessed using the acceptance of illness scale (AIS)...
November 12, 2016: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/27750480/the-relationship-of-salivary-testosterone-and-male-sexual-dysfunction-in-opioid-associated-androgen-deficiency-opiad
#20
Raquel Ajo, Ana Segura, Laura Mira, María-Del-Mar Inda, Rocío Alfayate, Angel Sánchez-Barbie, César Margarit, Ana M Peiró
BACKGROUND: Opioids are an effective treatment for chronic non-malignant pain (CNP). Long-term use risks and side effects such as opioid-induced androgen deficiency (OPIAD) exist. This could be measured by saliva testosterone (Sal-T). OBJECTIVES: To evaluate OPIAD in long-term opioid use in CNP patients. METHODS: A cross-sectional study included CNP male outpatients under opioid treatment. Total-Testosterone (Total-T), Free-Testosterone (Free-T), Bio-Testosterone (Bio-T) and Sal-T were measured...
October 18, 2016: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
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