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Sexually Transmitted Infections

Nicole Theresa Burton, Kavita Misra, Angelica Bocour, Sharmila Shah, Rodolfo Gutierrez, Chi-Chi Udeagu
OBJECTIVES: Condomless anal intercourse contributes significantly to the spread of HIV among men who have sex with men (MSM). Factors related to condomless anal intercourse with known HIV-positive partners among MSM are not well understood. The authors describe factors associated with inconsistent condom use with known HIV-positive partners prior to participants' diagnosis with HIV. METHODS: New York City health department disease intervention specialists interviewed newly HIV-diagnosed MSM ages ≥13 years reporting knowingly having anal sex with HIV-positive partners between June 2013 and October 2014...
November 8, 2018: Sexually Transmitted Infections
Launcelot McGrath, Christopher K Fairley, Eoin F Cleere, Catriona S Bradshaw, Marcus Y Chen, Eric P F Chow
OBJECTIVE: In mid-2017, the Victorian Government funded a free time-limited human papillomavirus (HPV) vaccination catch-up programme for gay and bisexual men who have sex with men (MSM) aged up to 26 years through sexual health clinics or other immunisation centres. We aimed to examine the uptake of the HPV vaccine among young MSM attending the Melbourne Sexual Health Centre (MSHC). METHODS: MSM aged ≤26 attending MSHC between 27 April 2017 and 31 December 2017 were included in the analysis...
November 8, 2018: Sexually Transmitted Infections
Nicola Low
No abstract text is available yet for this article.
October 19, 2018: Sexually Transmitted Infections
Maciej Pastuszczak, Bogdan Jakiela, Anna Wojas-Pelc
OBJECTIVES: Recent studies suggested that upregulation of anti-inflammatory immune response during early syphilis may be associated with persistence of Treponema pallidum infection despite adequate treatment, resulting in a serofast state. The objective of this study was to determine whether enhanced interleukin (IL)-10-related response during early T. pallidum infection increased the risk of serofast syphilis. METHODS: Two IL10 gene promoter polymorphisms affecting IL-10 production (-1082A>G [rs1800896], -592C>A [rs1800872]) and serum levels of IL-10 were measured in 80 patients with early syphilis before and 6  months after penicillin treatment and in 24 healthy volunteers (control group)...
October 19, 2018: Sexually Transmitted Infections
Simon Chengo Masha, Piet Cools, Eduard J Sanders, Mario Vaneechoutte, Tania Crucitti
OBJECTIVES: Trichomoniasis is the most prevalent curable STI globally, with the highest incidence and prevalence in sub-Saharan Africa (sSA). STIs have largely been associated with an increase in HIV acquisition. Our objective was to assess the existing literature available in English regarding the association of Trichomoniasis and HIV-1 acquisition. METHODS: The review protocol was registered at the International Prospective Register of Systematic Reviews (PROSPERO) under number CRD42018082702...
October 19, 2018: Sexually Transmitted Infections
Ricardo F Savaris, Daniele G Fuhrich, Rui V Duarte, Sebastian Franik, Jonathan D C Ross
OBJECTIVE: To assess the effectiveness and safety of antibiotic regimens used to treat pelvic inflammatory disease (PID). DESIGN: This is a systematic review and meta-analysis of randomised controlled trials (RCTs). Risk of bias was assessed using the criteria outlined in the Cochrane guidelines. Quality of evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation. DATA SOURCES: Eight electronic databases were searched from date of inception up to July 2016...
October 19, 2018: Sexually Transmitted Infections
Tristan J Barber, Tuvia Borok, Tara Suchak, Alison Weatherall, Tor Docherty, Natalie Gamble, Robert Pralat, Rusi Jaspal, Christine Cocker
No abstract text is available yet for this article.
October 18, 2018: Sexually Transmitted Infections
Qian Wang, Xiaomeng Ma, Xiaosong Zhang, Jason J Ong, Jun Jing, Lei Zhang, Lin-Hong Wang
OBJECTIVE: Women living with HIV (WLHIV) face disproportionately higher risks of acquiring human papillomavirus (HPV) compared with HIV negative counterparts. We aimed to investigate the prevalence of HPV in WLHIV in Chinese hospital setting and identify associated factors to the progression of late-stage cervical intraepithelial neoplasia (CIN2+) in this population. METHOD: This retrospective study collected data from 183 WLHIV on antiretroviral treatment (ART), based on reproductive health questionnaires...
October 18, 2018: Sexually Transmitted Infections
Nitika Pant Pai, Jana Daher, H R Prashanth, Achal Shetty, Rani Diana Sahni, Rajesh Kannangai, Priya Abraham, Rita Isaac
OBJECTIVES: In rural pregnant Indian women, multiple missed antenatal screening opportunities due to inadequate public health facility-based screening result in undiagnosed HIV and sexually transmitted bloodborne infections (STBBIs) and conditions (anaemia). Untreated infections complicate pregnancy management, precipitate adverse outcomes and risk mother-to-child transmission. Additionally, a shortage of trained doctors, rural women's preference for home delivery and health illiteracy affect health service delivery...
October 15, 2018: Sexually Transmitted Infections
Laura A S Quilter, Eve Obondi, Colin Kunzweiler, Duncan Okall, Robert C Bailey, Gaston Djomand, Boaz Otieno-Nyunya, Fredrick Otieno, Susan M Graham
OBJECTIVES: In settings where laboratory capacity is limited, the WHO recommends presumptive treatment for Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT) in asymptomatic men who have sex with men (MSM) at high risk for these infections. However, little is known about how best to target this intervention. We aimed to identify correlates of anorectal NG/CT infection in Kenyan MSM with and without anorectal symptoms and evaluate the performance of an empirical, model-based risk score to identify cases in asymptomatic men...
September 21, 2018: Sexually Transmitted Infections
Alex J Warr, Jillian Pintye, John Kinuthia, Alison L Drake, Jennifer A Unger, R Scott McClelland, Daniel Matemo, Lusi Osborn, Grace John-Stewart
OBJECTIVES: We evaluated the relationship of sexually transmitted infections (STIs) and genital infections during pregnancy and subsequent risk for infant mortality and stillbirth. METHODS: This was a nested longitudinal analysis using data from a study of peripartum HIV acquisition in Kenya. In the parent study, HIV-uninfected women were enrolled during pregnancy and followed until 9 months postpartum. For this analysis, women who tested positive for HIV at any point, had a non-singleton pregnancy or a spontaneous abortion <20 weeks were excluded...
September 18, 2018: Sexually Transmitted Infections
Jolijn M Zwart, Marie-Josee J Mangen, Menne Bartelsman, Martijn S van Rooijen, Henry J C de Vries, Maria Xiridou
OBJECTIVE: To assess the cost-effectiveness of three testing strategies with or without light microscopic Gram-stained smear (GSS) evaluation for the detection of anogenital gonorrhoea among men who have sex with men (MSM) at the Amsterdam STI clinic using a healthcare payer perspective. METHODS: Three testing strategies for MSM were compared: (1) GSS in symptomatic MSM only (currently practised strategy), (2) no GSS and (3) GSS in symptomatic and asymptomatic MSM...
September 8, 2018: Sexually Transmitted Infections
Ryosuke Omori, Hiam Chemaitelly, Christian L Althaus, Laith J Abu-Raddad
OBJECTIVES: To explore whether existence of long-lasting partial immunity against reinfection with Chlamydia trachomatis is necessary to explain C. trachomatis prevalence patterns by age and sexual risk, and to provide a plausible estimate for the effect size, defined here as a reduction in susceptibility to reinfection. METHODS: A population-based mathematical model was constructed to describe C. trachomatis natural history and transmission dynamics by age and sexual risk...
September 4, 2018: Sexually Transmitted Infections
Laura C Chambers, Jennifer L Morgan, M Sylvan Lowens, Tashina S Robinson, Sarah S Romano, Gina L Leipertz, James P Hughes, Matthew R Golden, Christine M Khosropour, David N Fredricks, Lisa E Manhart
OBJECTIVE: Although Chlamydia trachomatis (CT) and Mycoplasma genitalium (MG) are major causes of non-gonococcal urethritis (NGU), up to 50% of cases are of unknown aetiology. We sought to identify urethral exposures at last sexual episode associated with NGU and non-CT/non-MG NGU to identify anatomical sites from which aetiologically relevant micro-organisms may be acquired. METHODS: We enrolled STD clinic patients with and without NGU assigned male sex at birth and age ≥16 into a cross-sectional study...
September 4, 2018: Sexually Transmitted Infections
Cari van Schalkwyk, Jennifer Moodley, Alex Welte, Leigh Francis Johnson
OBJECTIVES: Cohort studies have shown significant increased risk of HIV acquisition following human papillomavirus (HPV) detection and increased risk of new HPV detection in individuals with HIV infection, after adjusting for behavioural risk factors. This study uses an individual-based model to assess whether confounding sexual behaviour factors and network level effects can explain these associations between HIV and HPV infection status, without biological interactions. METHODS: The model simulates infection with 13 oncogenic HPV types and HIV...
August 31, 2018: Sexually Transmitted Infections
Jo Gibbs, Soazig Clifton, Pam Sonnenberg, Ann Blandford, Anne M Johnson, Claudia S Estcourt
No abstract text is available yet for this article.
August 31, 2018: Sexually Transmitted Infections
Mance E Buttram, Maria E Pagano, Steven P Kurtz
OBJECTIVES: Foster care history is associated with many health and social problems, including sexual risk behaviours, HIV and other sexually transmitted infections (STIs). This cross-sectional study compares sexual risk behaviours among a sample of young adult substance users in Miami (N=602) with and without foster care histories. METHODS: Participants completed a comprehensive assessment which included sections on foster care, sexual risk behaviours and related health and social problems...
August 31, 2018: Sexually Transmitted Infections
Janneke P Bil, Maria Prins, Ibidun Fakoya, Alain Volny-Anne, Fiona Burns, Freke R Zuure
OBJECTIVES: Self-tests are performed and interpreted autonomously by a person without involving a healthcare professional or a certified laboratory. To gain insight into the usage of purchased HIV self-tests (HIVST) among migrants living in high-income countries, we studied the prevalence and determinants of HIVST usage among migrants living in the UK, France and the Netherlands. METHODS: We used web-based questionnaire data collected between April 2014 and July 2015 among migrants living in the UK, France and the Netherlands who participated in the cross-sectional community survey of the aMASE (advancing Migrant Access to health Services in Europe) study...
August 31, 2018: Sexually Transmitted Infections
Mirian Pinheiro Bruni, Mariangela Freitas da Silveira, Dulce Stauffert, Guilherme Lucas de Oliveira Bicca, Carolina Caetano Dos Santos, Nara Amélia da Rosa Farias, Daniel Golparian, Magnus Unemo
OBJECTIVES: Trichomonas vaginalis (TV) infection is the most common non-viral STI globally and can result in adverse pregnancy outcomes and exacerbated HIV acquisition/transmission. Nucleic acid amplification tests (NAATs) are the most sensitive diagnostic tests, with high specificity, but TV NAATs are rarely used in Brazil. We investigated the TV prevalence and compared the performance of the US Food and Drug Association-cleared Aptima TV assay with microscopy (wet mount and Gram-stained) and culture for TV detection in women in Pelotas, Brazil in an observational study...
August 28, 2018: Sexually Transmitted Infections
Alexandra C Barger, William S Pearson, Christofer Rodriguez, David Crumly, Georgia Mueller-Luckey, Wiley D Jenkins
OBJECTIVE: Chlamydia, gonorrhoea and syphilis (primary and secondary) are at high levels in the USA. Disparities by race, gender and sexual orientation have been characterised, but while there are indications that rural poor populations may also be at distinct risk this has been subjected to little study by comparison. The federally designated Delta Regional Authority, similar in structure to the Appalachian Regional Commission, oversees 252 counties within eight Mississippi Delta states experiencing chronic economic and health disparities...
August 27, 2018: Sexually Transmitted Infections
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