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Sexually Transmitted Infections

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https://www.readbyqxmd.com/read/28724744/ten-years-transmission-of-the-new-variant-of-chlamydia-trachomatis-in-sweden-prevalence-of-infections-and-associated-complications
#1
Jenny Dahlberg, Ronza Hadad, Karin Elfving, Inger Larsson, Jenny Isaksson, Anders Magnuson, Hans Fredlund, Magnus Unemo, Bjőrn Herrmann
OBJECTIVES: In 2006, a new variant of Chlamydia trachomatis (nvCT) was discovered in Sweden. It has a deletion in the plasmid resulting in failed detection by the single target systems from Abbott and Roche used at that time, whereas the third system used, from Becton Dickinson (BD), detects nvCT. The proportion of nvCT was initially up to 65% in counties using Abbott/Roche systems. This study analysed the proportion of nvCT from 2007 to 2015 in four selected counties and its impact on chlamydia-associated complications...
July 19, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28724743/improving-the-healthcare-response-to-domestic-violence-and-abuse-in-sexual-health-clinics-feasibility-study-of-a-training-support-and-referral-intervention
#2
Alex Hardip Sohal, Neha Pathak, Sarah Blake, Vanessa Apea, Judith Berry, Jayne Bailey, Chris Griffiths, Gene Feder
OBJECTIVES: Sexual health and gynaecological problems are the most consistent and largest physical health differences between abused and non-abused female populations. Sexual health services are well placed to identify and support patients experiencing domestic violence and abuse (DVA). Most sexual health professionals have had minimal DVA training despite English National Institute for Health and Care Excellence recommendations. We sought to determine the feasibility of an evidence-based complex DVA training intervention in female sexual health walk-in services (IRIS ADViSE: Identification and Referral to Improve Safety whilst Assessing Domestic Violence in Sexual Health Environments)...
July 19, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28717051/detection-of-markers-predictive-of-macrolide-and-fluoroquinolone-resistance-in-mycoplasma-genitalium-from-patients-attending-sexual-health-services-in-england
#3
Rachel Pitt, Helen Fifer, Neil Woodford, Sarah Alexander
OBJECTIVES: Resistance to both macrolides and fluoroquinolones has been reported in Mycoplasma genitalium; however, due to limited diagnostics, studies are often small and confined to specific geographical areas. This study sought to determine the rate of predicted resistance in M. genitalium-positive specimens referred for diagnostic testing. METHODS: Seventy-four M. genitalium-positive specimens, referred to the national reference laboratory (2010-2013) from 19 centres across England, were blinded and anonymised...
July 17, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28717050/which-azithromycin-regimen-should-be-used-for-treating-mycoplasma-genitalium-a-meta-analysis
#4
REVIEW
Patrick Horner, Suzanne M Ingle, Frederick Garrett, Karla Blee, Fabian Kong, Peter Muir, Harald Moi
BACKGROUND: There is increasing evidence that azithromycin 1 g is driving the emergence of macrolide resistance in Mycoplasma genitalium worldwide. We undertook a meta-analysis of M. genitalium treatment studies using azithromycin 1 g single dose and azithromycin 500 mg on day 1 then 250 mg daily for 4 days (5-day regimen) to determine rates of treatment failure and resistance in both regimens. METHODS: The online databases PubMed and Medline were searched using terms "Mycoplasma genitalium", "macrolide" or "azithromycin" and "resistance" up to April 2016...
July 17, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28705938/can-enhanced-screening-of-men-with-a-history-of-prior-syphilis-infection-stem-the-epidemic-in-men-who-have-sex-with-men-a-mathematical-modelling-study
#5
Ashleigh R Tuite, Souradet Shaw, Joss N Reimer, Craig P Ross, David N Fisman, Sharmistha Mishra
OBJECTIVES: The aim of this study is to determine the transmission impact of using prior syphilis infection to guide a focused syphilis screening intervention among men who have sex with men (MSM). METHODS: We parameterised a deterministic model of syphilis transmission in MSM to reflect the 2011-2015 syphilis outbreak in Winnipeg, Canada. Enhanced screening of 75% of men with prior syphilis every 3 months (A) was compared with distributing equivalent number tests to all MSM (B) or those with the highest partner number (C)...
July 13, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28698211/extra-rectal-lymphogranuloma-venereum-in-france-a-clinical-and-molecular-study
#6
Arnaud Desclaux, Arabella Touati, Didier Neau, Cécile Laurier-Nadalié, Cécile Bébéar, Bertille de Barbeyrac, Charles Cazanave
OBJECTIVES: To describe a series of extrarectal lymphogranuloma venereum (LGV) cases diagnosed in France. METHODS: Consecutive LGV cases confirmed at the French Reference Centre for chlamydiae with an extrarectal sample from January 2010 to December 2015 were included. The first part of the study consisted of a retrospective case note review and analysis. In a second part, the complete ompA gene sequence of our samples was determined. RESULTS: There were 56 cases overall: 50 cases of genital LGV and six cases of pharyngeal LGV...
July 11, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28684611/rapid-and-point-of-care-tests-for-the-diagnosis-of-trichomonas-vaginalis-in-women-and-men
#7
Charlotte A Gaydos, Jeffrey D Klausner, Nitika Pant Pai, Helen Kelly, Cordelia Coltart, Rosanna W Peeling
BACKGROUND: Trichomonasvaginalis (TV) is a highly prevalent parasitic infection worldwide. It is associated with many adverse reproductive health outcomes. Many infections are asymptomatic and syndromic management leads to underdetection of TV. Traditional methods of TV detection such as wet preparation are insensitive. New rapid, point-of-care (POC) tests can enhance the diagnosis of trichomoniasis. METHODS: The authors reviewed the literature and discuss older POC tests for TV detection, as well as the OSOM lateral flow test, the AmpliVue test, the Solana test and the GeneXpert test as well as the limitations of wet preparation and culture for detection of TV...
July 6, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28684610/rapid-accurate-point-of-care-tests-combining-diagnostics-and-antimicrobial-resistance-prediction-for-neisseria-gonorrhoeae-and-mycoplasma-genitalium
#8
Syed Tariq Sadiq, Fulvia Mazzaferri, Magnus Unemo
In addition to inadequate access to early diagnosis and treatment with antimicrobial agents for patients and sexual contacts, management and control of STIs is significantly challenged by emergence and spread of antimicrobial resistance (AMR), particularly for STIs such as Neisseria gonorrhoeae and Mycoplasma genitalium This is further compounded by use of nucleic acid amplification techniques for diagnosis, resulting in reduced phenotypic AMR testing for N. gonorrhoeae and absence or suboptimal AMR surveillance for guiding treatment of both STIs in many settings...
July 6, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28679630/condomless-sex-in-hiv-diagnosed-men-who-have-sex-with-men-in-the-uk-prevalence-correlates-and-implications-for-hiv-transmission
#9
Marina Daskalopoulou, Alison J Rodger, Andrew N Phillips, Lorraine Sherr, Jonathan Elford, Jeffrey McDonnell, Simon Edwards, Nicky Perry, Ed Wilkins, Simon Collins, Anne M Johnson, William J Burman, Andrew Speakman, Fiona C Lampe
OBJECTIVE: HIV transmission is ongoing among men who have sex with men (MSM) in the UK. Sex without a condom (condomless sex, CLS) is the main risk factor. We investigated the prevalence of and factors associated with types of CLS. METHODS: Cross-sectional questionnaire study in UK HIV clinics in 2011/2012 (ASTRA). MSM diagnosed with HIV for ≥3 months reported on anal and vaginal sex, CLS with HIV-serodifferent partners (CLS-D) and CLS with HIV-seroconcordant (CLS-C) partners in the previous 3 months...
July 5, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28676558/willingness-to-change-behaviours-to-reduce-the-risk-of-pharyngeal-gonorrhoea-transmission-and-acquisition-in-men-who-have-sex-with-men-a-cross-sectional-survey
#10
Eric Pf Chow, Sandra Walker, Tiffany Phillips, Christopher K Fairley
OBJECTIVES: The aim of this study was to examine the willingness of men who have sex with men (MSM) to change their behaviours to potentially reduce the risk of pharyngeal gonorrhoea transmission and acquisition. METHODS: A cross-sectional questionnaire-based study was conducted among MSM attending the Melbourne Sexual Health Centre, Australia, between March and September 2015. Participants were asked how likely they would change their behaviours to reduce the risk of pharyngeal gonorrhoea...
July 4, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28637906/anogenital-warts-and-other-hpv-associated-anogenital-lesions-in-the-hiv-positive-patient-a-systematic-review-and-meta-analysis-of-the-efficacy-and-safety-of-interventions-assessed-in-controlled-clinical-trials
#11
Ricardo Niklas Werner, Lukas Westfechtel, Corinna Dressler, Alexander Nast
OBJECTIVES: Anogenital warts (AGW, condylomata acuminata) and intraepithelial neoplasia (IEN) do not only impact health and social well-being, they are also associated with considerable costs for the healthcare systems. Immunocompromised and HIV-positive patients carry the highest epidemiological burden of human papillomavirus (HPV) infection and comprise a population specifically susceptible to treatment failures and recurrences. This systematic review aimed at identifying and appraising the available evidence from controlled studies of interventions for the treatment of AGW and IEN in immunocompromised patients...
June 21, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28619732/genital-herpes
#12
Rajul Patel
No abstract text is available yet for this article.
June 15, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28615327/where-are-we-now-a-multicountry-qualitative-study-to-explore-access-to-pre-antiretroviral-care-services-a-precursor-to-antiretroviral-therapy-initiation
#13
Dominic Bukenya, Alison Wringe, Mosa Moshabela, Morten Skovdal, Robert Ssekubugu, Sara Paparini, Jenny Renju, Estelle McLean, Oliver Bonnington, Joyce Wamoyi, Janet Seeley
OBJECTIVE: To explore barriers and facilitators to accessing postdiagnosis HIV care in five sub-Saharan African countries. METHODS: -ResultsAffordability: Transport and treatment costs were a barrier to HIV care, although some participants travelled to distant clinics to avoid being seen by people who knew them or for specific services. Broken equipment and drug stock-outs in local clinics could also necessitate travel to other facilities.Availability: Some facilities did not offer full HIV care, or only offered all services intermittently...
June 14, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28601793/anal-cancer-in-women-are-we-appropriately-identifying-the-risks
#14
EDITORIAL
Danielle Solomon, Margaret Stanley, Angela J Robinson
No abstract text is available yet for this article.
June 10, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28601792/talking-about-homosexuality-lessons-learned-from-1949
#15
LETTER
Catherine H Mercer, Anne M Johnson
No abstract text is available yet for this article.
June 10, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28600332/contaminated-fingers-a-potential-cause-of-chlamydia-trachomatis-positive-urine-specimens
#16
Philip M Giffard, Rachael A Lilliebridge, Judith Wilson, Gerald Murray, Samuel Phillips, Sepehr N Tabrizi, Suzanne M Garland, Louise Martin, Gurmeet Singh, Steven Y C Tong, Deborah C Holt, Patiyan Andersson
OBJECTIVES: The detection of an STI agent in a urogenital tract (UGT) specimen from a young child is regarded as being indicative of sexual abuse. However, the probabilities of contamination events that could conceivably lead to STI positive specimens in the absence of sexual contact are unclear. The objective was to estimate the potential for fingers that have come in contact with Chlamydia trachomatis-positive urine to detectably contaminate C. trachomatis-negative urine. METHODS: The study design was based on self-experimentation...
June 9, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28600331/does-maternal-hsv-2-coinfection-increase-mother-to-child-transmission-of-hiv-a-systematic-review
#17
REVIEW
Vishalini Sivarajah, Kevin Venus, Mark H Yudin, Kellie E Murphy, Steven A Morrison, Darrell Hs Tan
BACKGROUND: Reducing HIV mother-to-child transmission (MTCT) is critical to ending the HIV pandemic. Reports suggest that herpes simplex virus-2 (HSV-2), a common coinfection in HIV-infected individuals, is associated with increased MTCT, but results have been conflicting. We conducted a systematic review of observational studies to quantify the magnitude of this relationship (PROSPERO no. CRD42016043315). METHODS: We searched Medline (1981 to June week 3, 2016), EMBASE (1981 to week 26, 2016), relevant conferences (2013-2016) and bibliographies of identified studies for cohort and case-control studies enrolling HIV-positive women during pregnancy or peripartum that quantified the effect of HSV-2 infection on MTCT...
June 9, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28596369/hiv-prevalence-and-related-risk-behaviours-in-female-seasonal-farm-workers-in-souss-massa-draa-morocco-results-from-a-cross-sectional-survey-using-cluster-based-sampling
#18
Ivana Bozicevic, Fatiha Guezzar, Aleksandar Stulhofer, Aziza Bennani, Senad Handanagic, Jelena Barbaric, Houssine El Rhilani, Kamal Alami, Hamida Khattabi, Gabriele Riedner, Abderrahmane Maaroufi
OBJECTIVES: To determine prevalence of HIV and HIV-related behaviours in female seasonal farm workers (FSFWs) in two provinces of Souss Massa Draa (SMD) region in Morocco. SMD has a higher burden of HIV compared with other parts of Morocco and is characterised by a substantial aggregation of FSFW. METHODS: We carried out a cross-sectional HIV biobehavioural survey using cluster-based sampling of farms in the provinces Chtouka Aït Baha and Taroudant Ouled Teïma in 2014...
June 8, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28554893/concordance-between-self-reported-sti-history-and-biomedical-results-among-men-who-have-sex-with-men-in-los-angeles-california
#19
Nicole J Cunningham, Matthew R Beymer, Marjan Javanbakht, Chelsea L Shover, Robert K Bolan
OBJECTIVES: HIV studies and risk assessments among men who have sex with men (MSM) frequently use self-reported STI history as a proxy for true STI history. The objective of our study was to assess the validity of self-reported STI history through comparison with laboratory-confirmed biomedical results. METHODS: Data were analysed for MSM attending the Los Angeles LGBT Center (the Center) from August 2011 to July 2015. We identified 10 529 unique MSM who received testing for chlamydia, gonorrhoea and/or syphilis and had a later visit in which they self-reported their STI history to a clinic counsellor during a risk assessment...
May 29, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28515200/impact-of-expedited-partner-therapy-ept-implementation-on-chlamydia-incidence-in-the-usa
#20
Okeoma Mmeje, Sarah Wallett, Giselle Kolenic, Jason Bell
OBJECTIVES: The diagnosis and treatment of Chlamydia trachomatis infection is important in preventing persistent or recurrent infection. Expedited partner therapy (EPT) is the favoured and supported method for STI treatment of the Centers for Disease Control and Prevention when the provider cannot be assured that all recent sexual partner(s) will seek therapy. EPT is legally permissible in 38 states and is endorsed by healthcare organisations to decrease the rates of chlamydia and gonorrhoea infection...
May 17, 2017: Sexually Transmitted Infections
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