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Sexually Transmitted Infections

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https://www.readbyqxmd.com/read/28899995/hiv-seroconversion-among-baltimore-city-residents-tested-at-a-mobile-van-programme
#1
Sarah Puryear, Phyllis Burnett, Kathleen R Page, Ravikiran Muvva, Patrick Chaulk, Khalil G Ghanem, Anne Monroe
BACKGROUND: Many individuals with HIV in the USA are unaware of their diagnosis, and therefore cannot be engaged in treatment services, have worse clinical outcomes and are more likely to transmit HIV to others. Mobile van testing may increase HIV testing and diagnosis. Our objective was to characterise risk factors for HIV seroconversion among individuals using mobile van testing. METHODS: A case cohort study (n=543) was conducted within an HIV surveillance dataset of mobile van testing users with at least two HIV tests between September 2004 and August 2009 in Baltimore, Maryland...
September 12, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28866637/detection-of-human-papillomavirus-in-urine-among-heterosexual-men-in-relation-to-location-of-genital-warts-and-circumcision-status
#2
Ei T Aung, Christopher K Fairley, Sepehr N Tabrizi, Jennifer A Danielewski, Jason J Ong, Marcus Y Chen, Catriona S Bradshaw, Eric P F Chow
OBJECTIVE: Human papillomavirus (HPV) surveillance is important to monitor the effectiveness of national HPV vaccination programmes. Positivity of HPV in urine in men varies with different sampling methods. We aimed to determine the positivity for detection of HPV-6/11 in urine samples among men in relation to the position of genital warts and circumcision status. METHOD: We analysed stored chlamydia-positive urine specimens in young heterosexual men aged less than 25 years attending Melbourne Sexual Health Centre, Australia, between 2004 and 2015, for HPV genotypes...
September 2, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28866636/transient-aortitis-documented-by-positron-emission-tomography-in-a-case-series-of-men-and-transgender-women-infected-with-syphilis
#3
Dvora Joseph Davey, Noah Kojima, Kelika A Konda, Pawan Gupta, Segundo R Leon, Gino M Calvo, Carlos F Caceres, Jeffrey D Klausner
OBJECTIVES: Syphilis infection persists globally contributing to preventable and treatable morbidity and mortality. How extensive early syphilis disseminates is unknown. To better understand the relationship between early syphilis infection and inflammation over time, our study enrolled six individuals recently infected with syphilis for sequential positron emission tomography (PET) scans. METHODS: We evaluated a case series of six individuals with high syphilis titres (two secondary, two early latent and two latent, unknown duration, but with high titre) who received sequential PET scans to assess inflammation over time and its response to treatment...
September 2, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28866635/acceptability-and-ease-of-use-of-mailed-hpv-self-collection-among-infrequently-screened-women-in-north-carolina
#4
Chelsea Anderson, Lindsay Breithaupt, Andrea Des Marais, Charlotte Rastas, Alice Richman, Lynn Barclay, Noel T Brewer, Jennifer S Smith
OBJECTIVES: Self-collection of cervico-vaginal samples for human papillomavirus (HPV) testing has the potential to make cervical cancer screening more accessible to underscreened women. We evaluated the acceptability and ease of use of home-based HPV self-collection within a diverse population of low-income, infrequently screened women. METHODS: Participants were low-income women from North Carolina who had not received Pap testing in 4 or more years. Eligible women received a self-collection kit containing instructions and a brush for home-based sample collection...
September 2, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28860200/acute-hepatitis-a-infection-after-hepatitis-a-immunity-in-a-hiv-positive-individual
#5
Ming Jie Lee, Sam Douthwaite, Ranjababu Kulasegaram
Hepatitis A is a self-limiting infection caused by the hepatitis A virus (HAV), transmitted predominantly by the faecal-oral route including some sexual practices. Outbreaks are commonly reported in the men who have sex with men (population. Previous exposure is thought to provide life-long immunity against subsequent infections with the development of an HAV IgG response. This paper reports a case of acute Hepatitis A infection, despite evidence of a previously positive Hepatitis A IgG results in an HIV-positive individual...
August 31, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28844045/language-matters-a-linguist-s-view-on-medicine
#6
EDITORIAL
Dariusz Galasinski
No abstract text is available yet for this article.
August 26, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28844044/the-antibiotic-management-of-gonorrhoea-in-ontario-canada-following-multiple-changes-in-guidelines-an-interrupted-time-series-analysis
#7
Catherine Dickson, Monica Taljaard, Dara Spatz Friedman, Gila Metz, Tom Wong, Jeremy M Grimshaw
OBJECTIVE: This study assessed adherence with first-line gonorrhoea treatment recommendations in Ontario, Canada, following recent guideline changes due to antibiotic resistance. METHODS: We used interrupted times-series analyses to analyse treatment data for cases of uncomplicated gonorrhoea reported in Ontario, Canada, between January 2006 and May 2014. We assessed adherence with first-line treatment according to the guidelines in place at the time and the use of specific antibiotics over time...
August 26, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28844043/opportunities-and-barriers-to-sti-testing-in-community-health-centres-in-china-a-nationwide-survey
#8
Jason J Ong, Minghui Peng, Shanzhu Zhu, Ying-Ru J Lo, Christopher K Fairley, Michael R Kidd, Martin Roland, Sunfang Jiang, William C W Wong
BACKGROUND: China has strengthened its primary care workforce and implemented a wide network of community health centres (CHCs). However, STI testing and management are not currently included in the 'Essential Package of Primary Health Care in China'. Legislation change to encourage STI service delivery would be important, but it is also critical to determine if there are also provider-related opportunities and barriers for implementing effective STI programmes through CHCs if future legislation were to change...
August 26, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28835533/a-phase-ii-clinical-study-to-assess-the-feasibility-of-self-and-partner-anal-examinations-to-detect-anal-canal-abnormalities-including-anal-cancer
#9
Alan G Nyitray, Joseph T Hicks, Lu-Yu Hwang, Sarah Baraniuk, Margaret White, Stefanos Millas, Nkechi Onwuka, Xiaotao Zhang, Eric L Brown, Michael W Ross, Elizabeth Y Chiao
OBJECTIVE: Anal cancer is a common cancer among men who have sex with men (MSM); however, there is no standard screening protocol for anal cancer. We conducted a phase II clinical trial to assess the feasibility of teaching MSM to recognise palpable masses in the anal canal which is a common sign of anal cancer in men. METHODS: A clinician skilled in performing digital anorectal examinations (DARE) used a pelvic manikin to train 200 MSM, aged 27-78 years, how to do a self-anal examination (SAE) for singles or a partner anal examination (PAE) for couples...
August 23, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28835532/sensitivity-of-the-stat-view-rapid-self-test-and-implications-for-use-during-acute-hiv-infection
#10
Narjis Boukli, Anders Boyd, NoƩmie Wendremaire, Pierre-Marie Girard, Julie Bottero, Laurence Morand-Joubert
OBJECTIVES: HIV testing is an important step towards diminishing incident infections. Rapid self-tests whose use is becoming more common in France could help increase access to testing, yet could fail to diagnose HIV during acute HIV infection (AHI). The aim of the present study was to evaluate HIV-detection sensitivity of a commonly used rapid self-test (STAT-VIEW HIV1/2), compared with another point-of-care rapid test (INSTI), among patients presenting with AHI. METHODS: Individuals tested at Saint-Antoine Hospital (Paris, France) with negative or indeterminate western blot (WB) results and detectable HIV-RNA were included...
August 23, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28822976/persistence-after-treatment-of-pharyngeal-gonococcal-infections-in-patients-of-the-sti-clinic-amsterdam-the-netherlands-2012-2015-a-retrospective-cohort-study
#11
I Putu Yuda Hananta, Henry John Christiaan De Vries, Alje P van Dam, Martijn Sebastiaan van Rooijen, Hardyanto Soebono, Maarten Franciscus Schim van der Loeff
INTRODUCTION: Infection of Neisseria gonorrhoeae in the pharynx (pharyngeal Ng) is associated with gonococcal transmission and development of antimicrobial resistance. We assessed proportion of and determinants for persistence after treatment of pharyngeal Ng. METHODS: At the STI clinic of Amsterdam, the Netherlands, females-at-risk and men who have sex with men are routinely screened for pharyngeal Ng using an RNA-based nucleic acid amplification test (NAAT; Aptima Combo 2)...
August 19, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28819018/adjuvant-treatment-of-anogenital-warts-with-systemic-interferon-a-systematic-review-and-meta-analysis
#12
Lukas Westfechtel, Ricardo Niklas Werner, Corinna Dressler, Matthew Gaskins, Alexander Nast
BACKGROUND: Interferons are natural messenger proteins that are used to treat various disease entities. Due to their immunomodulating, antiviral and antiproliferative effects, the systemic administration of interferons after ablative treatment for anogenital warts (AGWs) has been advocated to increase clearance and decrease recurrence rates. However, studies investigating the efficacy of adjuvant systemic interferon have yielded inconsistent results. The objective of this systematic review and meta-analysis was to comprehensively assess and evaluate the available evidence from randomised controlled trials...
August 17, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28798195/cross-sectional-study-to-evaluate-trichomonas-vaginalis-positivity-in-women-tested-for-neisseria-gonorrhoeae-and-chlamydia-trachomatis-attending-genitourinary-medicine-and-primary-care-clinics-in-bristol-south-west-england
#13
Jane E Nicholls, Katy M E Turner, Paul North, Ralph Ferguson, Margaret T May, Karen Gough, John Macleod, Peter Muir, Patrick J Horner
BACKGROUND: Highly sensitive, commercial nucleic acid amplification tests (NAAT) for Trichomonas vaginalis have only recently been recommended for use in the UK. While testing for T. vaginalis is routine in symptomatic women attending genitourinary medicine (GUM) clinics, it is rare in asymptomatic women or those attending primary care. The aim of this study was to evaluate the positivity of T. vaginalis using a commercial NAAT, in symptomatic and asymptomatic women undergoing testing for chlamydia and gonorrhoea in GUM and primary care settings...
August 10, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28784618/genetic-transmission-networks-reveal-the-transmission-patterns-of-hiv-1-crf01_ae-in-china
#14
Xiaoshan Li, Rong Gao, Kexin Zhu, Feiran Wei, Kun Fang, Wei Li, Yue Song, You Ge, Yu Ji, Ping Zhong, Pingmin Wei
OBJECTIVES: The epidemic of HIV-1 CRF01_AE has become a major public health issue in China. This study aimed to characterise the transmission patterns of genetic networks for CRF01_AE nationwide and elucidate possible opportunities for prevention. METHODS: We isolated and conducted genetic transmission network analysis of all available CRF01_AE pol sequences (n=4704) from China in the Los Alamos HIV sequence database. RESULTS: A total of 1391 (29...
August 7, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28778981/role-of-dual-hiv-syphilis-test-kits-in-expanding-syphilis-screening
#15
EDITORIAL
Melanie M Taylor, Rosanna W Peeling, Igor Toskin, Massimo Ghinidelli
No abstract text is available yet for this article.
August 4, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28778980/places-and-people-the-perceptions-of-men-who-have-sex-with-men-concerning-sti-testing-a-qualitative-study
#16
Jessica Datta, David Reid, Gwenda Hughes, Catherine H Mercer, Sonali Wayal, Peter Weatherburn
OBJECTIVES: To explore the experiences and views of men who have sex with men (MSM) on attending clinical sexual health services and their preferences regarding service characteristics in the context of the disproportionate burden of STIs experienced by this group. The wider study aim was to develop a risk assessment tool for use in sexual health clinics. METHODS: Qualitative study comprising eight focus group discussions with 61 MSM in four English cities. Topics included: experience of attending sexual health services, perceptions of norms of attendance among MSM, knowledge of, and attitudes towards, STIs and views on 'being researched...
August 4, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28778979/assessing-for-domestic-violence-in-sexual-health-environments-a-qualitative-study
#17
Jeremy Horwood, Andrew Morden, Jayne E Bailey, Neha Pathak, Gene Feder
OBJECTIVES: Domestic violence and abuse (DVA) is a major clinical challenge and public health issue. Sexual health services are an important potential site of DVA intervention. The Assessing for Domestic Violence in Sexual Health Environments (ADViSE) intervention aimed to improve identification and management of DVA in sexual healthcare settings and is a modified version of the Identification and Referral to Improve Safety (IRIS) general practice programme. Our qualitative evaluation aimed to explore the experiences of staff participating in an IRIS ADViSE pilot...
August 4, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28760772/correction-identifying-factors-that-lead-to-the-persistence-of-imported-gonorrhoeae-strains-a-modelling-study
#18
LETTER
(no author information available yet)
No abstract text is available yet for this article.
July 31, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28756409/female-and-younger-subjects-have-lower-adherence-in-prep-trials-a-meta-analysis-with-implications-for-the-uptake-of-prep-service-to-prevent-hiv
#19
REVIEW
Ke Yun, Jun-Jie Xu, Jing Zhang, Jia-Ming Li, Qing-Hai Hu, Zhen-Xing Chu, Yong-Jun Jiang, Wen-Qing Geng, Hong Shang, Ning Wang
OBJECTIVE: To estimate the medicine-taking compliance (MTC) level, explore its facilitators and barriers, and quantify the association between MTC level and pre-exposure prophylaxis (PrEP) protective efficacy in individuals at risk of acquiring HIV being administered oral PrEP. DESIGN: Meta-analysis. DATA SOURCES: We searched PubMed, Cochrane and Embase databases for published randomized controlled trials (RCTs) pertaining to MTC of oral PrEP for HIV prevention up to 16 January 2017...
July 29, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28747410/a-systematic-review-and-meta-analysis-of-studies-evaluating-the-performance-and-operational-characteristics-of-dual-point-of-care-tests-for-hiv-and-syphilis
#20
REVIEW
Harriet D Gliddon, Rosanna W Peeling, Mary L Kamb, Igor Toskin, Teodora E Wi, Melanie M Taylor
BACKGROUND: Mother-to-child transmission (MTCT) of syphilis and HIV continue to be important yet preventable causes of perinatal and infant morbidity and mortality. OBJECTIVES: To systematically review, critically appraise and perform a meta-analysis to evaluate the operational characteristics of dual rapid diagnostic tests (RDTs) for HIV/syphilis and evaluate whether they are cost effective, acceptable and easy to use. DESIGN: Systematic review and meta-analysis...
July 26, 2017: Sexually Transmitted Infections
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