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Sleep & Breathing, Schlaf & Atmung

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https://www.readbyqxmd.com/read/29931497/impact-of-pap-therapy-on-hospitalization-rates-in-medicare-beneficiaries-with-copd-and-coexisting-osa
#1
Gurinder Singh, Amitesh Agarwal, Wei Zhang, Yong-Fang Kuo, Rizwana Sultana, Gulshan Sharma
OBJECTIVE: Growing evidence supports that patients with chronic obstructive pulmonary disease (COPD) and coexisting obstructive sleep apnea (OSA) have poor prognosis. This association is described as overlap syndrome. Positive airway pressure (PAP) therapy is now the preferred treatment for OSA. We hypothesized that use of PAP therapy in elderly patients with overlap syndrome would be associated with lower healthcare utilization. METHODS: In this retrospective cohort study, we analyzed data from 5% national sample of fee-for-service Medicare beneficiaries with a diagnosis of COPD who were newly started on PAP therapy in 2011...
June 22, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29926395/hypoglossal-nerve-stimulation-therapy-on-peripheral-arterial-tonometry-in-obstructive-sleep-apnea-a-pilot-study
#2
Allison K Ikeda, Qiao Li, Arshed A Quyuumi, Raj C Dedhia
PURPOSE: Hypoglossal nerve stimulation (HGNS) is being increasingly utilized in the setting of moderate-severe obstructive sleep apnea (OSA). While moderate-severe OSA confers excess cardiovascular risk, the impact of HGNS on cardiovascular requires further investigation. With the advent of peripheral arterial tonometry (PAT), one can non-invasively study real-time changes to the autonomic nervous system. This study evaluates the effect of HGNS therapy on autonomic output, using PAT-integrated polysomnography...
June 21, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29869108/chronic-pulmonary-disease-is-associated-with-pain-spreading-and-restless-legs-syndrome-in-middle-aged-women-a-population-based-study
#3
Zou Ding, Romana Stehlik, Jan Hedner, Jan Ulfberg, Ludger Grote
INTRODUCTION: Recent studies suggest an increased prevalence of chronic pain conditions and restless legs syndrome (RLS) in patients with chronic pulmonary disease (CPD). We analyzed the prevalence and risk factors for pain and RLS in a population-based sample of females with comorbid CPD. METHOD: Questionnaire-based data from 2745 women aged 18-64 years were analyzed regarding comorbid CPD status (severe bronchitis, emphysema, asthma). Pain status was assessed according to symptoms reflecting severity (Visual Analogue Scale, VAS rating 0-10) and duration and spreading (limited spread or widespread) of pain...
June 4, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29855775/hidden-secrets-of-the-upper-airway-on-the-track-to-individualized-sleep-medicine-highlights-from-the-2018-ats-conference-in-san-diego
#4
Nikolaus C Netzer, Linda Rausch, Petra Netzer
No abstract text is available yet for this article.
May 31, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29808290/sleep-apnea-detection-accuracy-of-using-automated-ecg-analysis-compared-to-manually-scored-polysomnography-apnea-hypopnea-index
#5
Hugi Hilmisson, Neale Lange, Stephen P Duntley
INTRODUCTION: Adequate sleep is fundamental to wellness and recovery from illnesses and lack thereof is associated with disease onset and progression resulting in adverse health outcomes. Measuring sleep quality and sleep apnea (SA) at the point of care utilizing data that is already collected is feasible and cost effective, using validated methods to unlock sleep information embedded in the data. The objective of this study is to determine the utility of automated analysis of a stored, robust signal widely collected in hospital and outpatient settings, a single lead electrocardiogram (ECG), using clinically validated algorithms, cardiopulmonary coupling (CPC), to objectively and accurately identify SA...
May 28, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29804216/oxidative-stress-in-obese-children-and-adolescents-with-and-without-type-2-diabetes-mellitus-is-not-associated-with-obstructive-sleep-apnea
#6
Riva Tauman, Shlomit Shalitin, Lena Lavie
PURPOSE: Obesity, obstructive sleep apnea (OSA), and type 2 diabetes mellitus (T2DM) are associated with chronic low-grade inflammation and oxidative stress. In adults, increased lipid peroxidation, a marker of oxidative stress, was found in both metabolic syndrome and OSA. Studies on oxidative stress in children with T2DM and OSA are scarce. METHODS: Plasma oxidized low-density lipoprotein (Ox-LDL) levels were evaluated in obese children and adolescents with/without T2DM, and the contribution of OSA to oxidative stress was investigated...
May 26, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29797188/a-detection-dog-for-obstructive-sleep-apnea
#7
Anni Koskinen, Adel Bachour, Jenni Vaarno, Heli Koskinen, Sari Rantanen, Leif Bäck, Tuomas Klockars
PURPOSE: We sought to assess whether a dog can be trained to distinguish obstructive sleep apnea patients from healthy controls based on the olfactory detection of urine. METHODS: Urine samples were collected from 23 adult male obstructive sleep apnea patients and from 20 voluntary adult male volunteers. Three dogs were trained through reinforced operant conditioning. RESULTS: Two of the three dogs correctly detected two thirds of obstructive sleep apnea patients (p < 0...
May 24, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29779142/arousal-index-as-a-marker-of-carotid-artery-atherosclerosis-in-patients-with-obstructive-sleep-apnea-syndrome
#8
Mayumi Suzuki, Ken Shimamoto, Haruki Sekiguchi, Takamitsu Harada, Natsumi Satoya, Yuji Inoue, Kazuhiro Yamaguchi, Masatoshi Kawana
PURPOSE: It was shown in a previous cohort study that men with internal carotid artery (ICA) plaque, defined as focal wall thickness of ≥ 1.5 mm, had a threefold higher risk of stroke than those without plaque. We examined the relationship between arousal indices and sleep stages in patients with obstructive sleep apnea syndrome (OSAS) and carotid atherosclerosis. METHODS: Carotid atherosclerosis severity was evaluated using the maximal carotid wall intima-media thickness of the ICA (ICA-maxIMT) and plaque in 83 patients with OSAS...
May 19, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29777431/modified-anterior-palatoplasty-and-double-suspension-sutures-with-or-without-tonsillectomy-in-selected-patients-with-obstructive-sleep-apnea-a-preliminary-report
#9
Sherif M Askar, Mohammad W El-Anwar, Ali Awad
BACKGROUND: Retropalatal region might be considered the most common site of obstruction in patients with snoring and OSA. We aimed at presentation of two combined techniques: modified anterior palatoplasty (MAP) and bilateral double suspension suture (DSS). METHODS: This prospective study was conducted on OSA patients with retro-palatal collapse only that was confirmed by nasoendoscopy during Muller's maneuver and drug induced sleep endoscopy. MAP and DSS were performed for all patients...
May 18, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29770919/dl-propargylglycine-protects-against-myocardial-injury-induced-by-chronic-intermittent-hypoxia-through-inhibition-of-endoplasmic-reticulum-stress
#10
Xiufang Zhou, Si Tang, Ke Hu, Zhan Zhang, Pei Liu, Yuchuan Luo, Jing Kang, Lifang Xu
BACKGROUND: Chronic intermittent hypoxia (CIH), an important basis of the pathogenesis of organ damage induced by obstructive sleep apnea syndrome (OSAS), is associated with myocardial injury, such as left ventricular dysfunction, apoptosis, and oxidative stress. Endogenous hydrogen sulfide (H2 S) plays an important role in maintaining cardiovascular functions. Many studies have demonstrated that exogenous H2 S has protective effects against myocardial injury induced by various cardiovascular diseases, and inhibiting the generation of endogenous H2 S has opposite effects...
May 16, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29766410/complete-concentric-collapse-at-the-soft-palate-in-sleep-endoscopy-what-change-is-possible-after-uppp-in-patients-with-cpap-failure
#11
Katrin Hasselbacher, A Seitz, N Abrams, B Wollenberg, A Steffen
PURPOSE: The aim of this work was to assess whether uvulopalatopharyngoplasty in patients with failure for positive airway pressure not only reduces the degree of obstructive sleep apnea but also to determine as well if it changes the collapse pattern of the soft palate and thereby fulfills the qualifications for implementing upper airway stimulation (UAS) as an adjunctive solution. METHOD: Fifteen patients with intolerance for positive airway pressure were included in this retrospective cohort study...
May 16, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29748792/the-independent-and-combined-effects-of-respiratory-events-and-cortical-arousals-on-the-autonomic-nervous-system-across-sleep-stages
#12
Jiuxing Liang, Xiangmin Zhang, Xiaomin He, Li Ling, Chunyao Zeng, Yuxi Luo
PURPOSE: During sleep, respiratory events readily modulate the autonomic nervous system (ANS). Whether such modulation is caused by the respiratory event itself or the cortical arousal that follows and whether these influences differ across sleep stages are not clear. Thus, we aimed to study the independent and combined effects of respiratory events and cortical arousals on the ANS across sleep stages. METHODS: We recruited 22 male patients with sleep apnea-hypopnea syndrome (SAHS) and analyzed the differences in the indices of heart rate variability among normal respiration (NR), pathological respiratory events without cortical arousals (PR), cortical arousals without respiratory events (CA), and the coexistence of PR and CA (PR&CA), by sleep stage...
May 10, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29744684/biochemical-markers-of-cardiac-dysfunction-in-children-with-obstructive-sleep-apnoea-osa
#13
Daniel Hirsch, Carla A Evans, Melanie Wong, Rita Machaalani, Karen A Waters
OBJECTIVES: We explored relationships between biochemical markers and cardiac responses of children with and without obstructive sleep apnoea (OSA) during exercise. We hypothesised that serum markers of sympathetic nervous system activity and low-grade inflammation would correlate with cardiac responses to exercise in children with or without OSA. METHODOLOGY: The study included 40 of 71 children with previously characterised responses to cardiopulmonary exercise testing...
May 9, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29728955/relationships-among-retropalatal-airway-pharyngeal-length-and-craniofacial-structures-determined-by-magnetic-resonance-imaging-in-patients-with-obstructive-sleep-apnea
#14
Suat Avci, Hatice Lakadamyali, Huseyin Lakadamyali, Erdinc Aydin, Mustafa Agah Tekindal
BACKGROUND: The integration of anatomical and nonanatomical parameters will improve our ability to predict the outcomes of OSA treatment. Currently, no standardized, quantitative classification of upper airway anatomical traits is available. The retropalatal (RP) airway is the most important area to consider when planning anatomical treatment. However, current evaluation methods feature qualitative conventional endoscopy. Here, we describe a quantitative magnetic resonance imaging (MRI) method used to classify RP airway patterns...
May 5, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29691799/the-discriminative-power-of-stop-bang-as-a-screening-tool-for-suspected-obstructive-sleep-apnea-in-clinically-referred-patients-considering-gender-differences
#15
Jin Mou, Bethann M Pflugeisen, Brian A Crick, Paul J Amoroso, Kirk T Harmon, Stephen F Tarnoczy, S Shirley Ho, Kimberly A Mebust
PURPOSE: Obstructive sleep apnea (OSA) is the most commonly seen clinical sleep disorder. STOP-Bang, a widely used screening tool, yields a composite score based on eight dichotomized items including male gender. This study was designed to validate STOP-Bang among clinically referred patients and tested alternative scoring designs on tool performance, with a focus on gender differences in OSA. METHOD: STOP-Bang was administered to 403 female and 532 male subjects, followed by comprehensive sleep evaluation that included measurement of apnea-hypopnea indexes...
April 24, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29687190/monitoring-healthy-and-disturbed-sleep-through-smartphone-applications-a-review-of-experimental-evidence
#16
REVIEW
Edita Fino, Michela Mazzetti
Smartphone applications are considered as the prime candidate for the purposes of large-scale, low-cost and long-term sleep monitoring. How reliable and scientifically grounded is smartphone-based assessment of healthy and disturbed sleep remains a key issue in this direction. Here we offer a review of validation studies of sleep applications to the aim of providing some guidance in terms of their reliability to assess sleep in healthy and clinical populations, and stimulating further examination of their potential for clinical use and improved sleep hygiene...
April 23, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29682699/effects-of-continuous-positive-airway-pressure-on-cardiovascular-biomarkers-in-patients-with-obstructive-sleep-apnea-a-meta-analysis-of-randomized-controlled-trials
#17
Yu Ning, Tian-Song Zhang, Wan-Wan Wen, Kun Li, Yun-Xiao Yang, Yan-Wen Qin, Hui-Na Zhang, Yun-Hui Du, Lin-Yi Li, Song Yang, Yun-Yun Yang, Miao-Miao Zhu, Xiao-Lu Jiao, Yan Zhang, Ming Zhang, Yong-Xiang Wei
PURPOSE: Obstructive sleep apnea (OSA) is associated with increased levels of systemic inflammatory markers, increased arterial stiffness, and endothelial dysfunction, which may lead to increased cardiovascular risk. We aimed to quantify the effects of continuous positive airway pressure (CPAP) on cardiovascular biomarkers and to establish predictors of response to CPAP. METHODS: We searched PubMed and the Cochrane Library from inception to May 31, 2017. Randomized controlled trials (RCTs) assessing the efficacy of CPAP on high-sensitivity C-reactive protein (hs-CRP), interleukin 6 (IL-6), tumor necrosis factor- alpha (TNF-α), augmentation index (AIx), pulse wave velocity (PWV), and flow-mediated dilatation (FMD) in patients with OSA were selected by consensus...
April 22, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29682698/validation-of-bahasa-malaysia-stop-bang-questionnaire-for-identification-of-obstructive-sleep-apnea
#18
Baharudin Abdullah, Anuar Idwan Idris, Zahiruddin Wan Mohammad, Hazama Mohamad
PURPOSE: The diagnosis of obstructive sleep apnea (OSA) by polysomnography (PSG) is time-consuming and expensive. The STOP-BANG questionnaire (SBQ) is an adequate screening tool and easily applied. We aimed to validate the Bahasa Malaysia version for use in sleep clinic. METHODS: A cross-sectional study was carried out in the sleep clinic. Standard forward-backward method was used for translation. Patients were required to answer a translated version of the questionnaire in Bahasa Malaysia and underwent a PSG study...
April 22, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29679310/the-association-of-snoring-and-risk-of-obstructive-sleep-apnea-with-poor-academic-performance-among-university-students
#19
Basheer Y Khassawneh, Loiy L Alkhatib, Ali M Ibnian, Yousef S Khader
STUDY OBJECTIVES: Subjects with obstructive sleep apnea (OSA) have neurocognitive dysfunction. The aim of this study was to estimate the prevalence of symptoms and risk of OSA among university students and the association with academic performance. METHODS: A cross-sectional study was conducted at Jordan University of Science and Technology. Students from faculties of engineering, medicine, nursing, pharmacy, and dentistry were asked to participate in this study...
April 20, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29671205/impact-of-continuous-positive-airway-pressure-on-vascular-endothelial-growth-factor-in-patients-with-obstructive-sleep-apnea-a-meta-analysis
#20
REVIEW
Jia-Chao Qi, LiangJi Zhang, Hao Li, Huixue Zeng, Yuming Ye, Tiezhu Wang, Qiyin Wu, Lida Chen, Qiaozhen Xu, Yifeng Zheng, Yaping Huang, Li Lin
PURPOSE: Cumulative evidence supports the clear relationship of obstructive sleep apnea (OSA) with cardiovascular disease (CVD). And, adherence to continuous positive airway pressure (CPAP) treatment alleviates the risk of CVD in subjects with OSA. Vascular endothelial growth factor (VEGF), a potent angiogenic cytokine regulated by hypoxia-inducible factor, stimulates the progression of CVD. Thus, whether treatment with CPAP can actually decrease VEGF in patients with OSA remains inconclusive...
April 18, 2018: Sleep & Breathing, Schlaf & Atmung
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