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Neuromodulation: Journal of the International Neuromodulation Society

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https://www.readbyqxmd.com/read/30221804/dependence-of-c-fos-expression-on-amplitude-of-high-frequency-spinal-cord-stimulation-in-a-rodent-model
#1
Shiying Li, Feng Ye, Jay P Farber, Bengt Linderoth, Tianhe Zhang, Jianwen Wendy Gu, Michael Moffitt, Kennon Garrett, Jiande Chen, Robert D Foreman
OBJECTIVES: Clinical high-frequency spinal cord stimulation (hfSCS) (>250 Hz) applied at subperception amplitudes reduces leg and low back pain. This study investigates, via labeling for c-fos-a marker of neural activation, whether 500 Hz hfSCS applied at amplitudes above and below the dorsal column (DC) compound action potential (CAP) threshold excites dorsal horn neurons. MATERIALS AND METHODS: DC CAP thresholds in rats were determined by applying single biphasic pulses of SCS to T12 -T13 segments using pulse widths of 40 or 200 μsec via a ball electrode placed over the left DC and increasing amplitude until a short latency CAP was observed on the L5 DC and sciatic nerve...
September 17, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/30211964/pre-operative-imaging-for-spinal-cord-stimulation-a-case-report-of-a-spinal-cord-tumor-identified-by-screening-magnetic-resonance-imaging-of-the-thoracic-spine
#2
LETTER
Lauren E Stone, Steven M Falowski
No abstract text is available yet for this article.
September 13, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/30160335/ultrasound-guided-percutaneous-peripheral-nerve-stimulation-neuromodulation-of-the-femoral-nerve-for-postoperative-analgesia-following-ambulatory-anterior-cruciate-ligament-reconstruction-a-proof-of-concept-study
#3
Brian M Ilfeld, Engy T Said, John J Finneran, Jacklynn F Sztain, Wendy B Abramson, Rodney A Gabriel, Bahareh Khatibi, Matthew W Swisher, Pia Jaeger, Dana C Covey, Catherine M Robertson
OBJECTIVES: The purpose of this prospective proof of concept study was to investigate the feasibility of using percutaneous peripheral nerve stimulation of the femoral nerve to treat pain in the immediate postoperative period following ambulatory anterior cruciate ligament reconstruction with a patellar autograft. MATERIALS AND METHODS: Preoperatively, an electrical lead (SPRINT, SPR Therapeutics, Inc., Cleveland, OH, USA) was percutaneously implanted with ultrasound guidance anterior to the femoral nerve caudad to the inguinal crease...
August 30, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/30153360/feasibility-of-computerized-cognitive-behavioral-therapy-combined-with-bifrontal-transcranial-direct-current-stimulation-for-treatment-of-major-depression
#4
Emma S Welch, Anne Weigand, Julia E Hooker, Noah S Philip, Audrey R Tyrka, Daniel Z Press, Linda L Carpenter
BACKGROUND: Cognitive behavioral therapy (CBT) is effective in the treatment of major depressive disorder (MDD). Transcranial Direct Current Stimulation (tDCS) has demonstrated preliminary antidepressant effects and beneficial effects on cognitive function. OBJECTIVE: We investigated the feasibility and acceptability of using tDCS to enhance the effects of computer-based CBT for treatment of MDD. MATERIALS AND METHODS: In a randomized, double-blind, sham-controlled study, 14 patients with MDD on stable or no pharmacotherapy received active or sham bifrontal tDCS for four weeks with concurrent CBT...
August 28, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/30152911/posterior-tibial-nerve-stimulation-for-the-treatment-of-fecal-incontinence-following-obstetric-anal-sphincter-injury
#5
Santosh Sanagapalli, Suzanne Harrington, Natalia Zarate-Lopez, Anton Emmanuel
OBJECTIVES: Obstetric anal sphincter injuries (OASI) are a major risk factor for fecal incontinence (FI). Neuromodulation is often used as second-line therapy for FI, but evidence for its efficacy is conflicting. We aimed to evaluate the efficacy and predictive factors of posterior tibial nerve stimulation for obstetric anal sphincter injury-induced FI. MATERIALS AND METHODS: Consecutive females with FI related to past OASI who had not responded to first-line therapy and had received 8-12 weeks of posterior tibial nerve stimulation were included...
August 28, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/30152898/long-term-outcome-following-implanted-pulse-generator-change-in-patients-treated-with-sacral-nerve-modulation-for-fecal-incontinence
#6
Adrien Le Fouler, Emilie Duchalais, Tse-Han Loong, Corine Baayen, Vincent Wyart, Caroline Kubis, Guillaume Meurette, Paul-Antoine Lehur
BACKGROUND: Long-term outcome of sacral nerve modulation (SNM) patients after implanted pulse generator (IPG) change for fecal incontinence (FI) is unknown. This study reported the outcome and long-term satisfaction after a change of an exhausted IPG, questioning the need to concurrently change the electrode and looking for factors involved in the maintenance of treatment efficiency. METHODS: Patients with fecal incontinence and with a Medtronic IPG implanted in a single center (2001-2016) were prospectively followed up...
August 28, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/30133071/fixed-life-or-rechargeable-battery-for-deep-brain-stimulation-which-do-patients-prefer
#7
Tahir Khaleeq, Harutomo Hasegawa, Michael Samuel, Keyoumars Ashkan
BACKGROUND: Deep brain stimulation (DBS) is increasingly used to treat a wide variety of neurological and psychiatric disorders. Implantable pulse generators (implantable pulse generators/batteries) for DBS were originally only available as a nonrechargeable option. However, there is now a choice between fixed-life and rechargeable batteries, with each having their own advantages and disadvantages. The extent of patient involvement in the choice of battery and the factors that matter to them have not been well studied...
August 22, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/30133066/dorsal-root-ganglion-stimulation-for-the-treatment-of-bilateral-intractable-chronic-testicular-pain
#8
LETTER
Mohamed Hassanain, Paul Murphy
No abstract text is available yet for this article.
August 22, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/30117650/return-to-work-of-patients-treated-with-spinal-cord-stimulation-for-chronic-pain-a-systematic-review-and-meta-analysis
#9
REVIEW
Maarten Moens, Lisa Goudman, Raf Brouns, Alexis Valenzuela Espinoza, Mats De Jaeger, Eva Huysmans, Koen Putman, Jan Verlooy
BACKGROUND: Chronic pain has a substantial negative impact on work-related outcomes, which underscores the importance of interventions to reduce the burden. Spinal cord stimulation (SCS) efficiently causes pain relief in specific chronic pain syndromes. The aim of this review was to identify and summarize evidence on returning to work in patients with chronic pain treated with SCS. MATERIALS AND METHODS: A systematic literature review was performed including studies from PubMed, EMBASE, SCOPUS, and Web of Science (up till October 2017)...
August 17, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/30117635/spinal-cord-stimulation-infection-rate-and-risk-factors-results-from-a-united-states-payer-database
#10
Steven M Falowski, David A Provenzano, Ying Xia, Alissa H Doth
OBJECTIVE: Surgical site infections can cause negative clinical and economic outcomes. A recent international survey on Spinal Cord Stimulation (SCS) infection control practices demonstrated low compliance with evidence-based guidelines. This study defines infection rate for SCS implants and identifies infection risk factors. MATERIALS AND METHODS: A retrospective analysis of the MarketScan® Databases identified patients with SCS implant (2009-2014) and continuous health plan enrollment for ≥12-months (12 m) preimplant...
August 17, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/30117630/sacral-burst-neuromodulation-via-caudal-approach-as-a-treatment-for-chronic-coccydynia
#11
LETTER
David W Lee, Albert Lai
No abstract text is available yet for this article.
August 17, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/30117624/selective-decrease-in-allodynia-with-high-frequency-neuromodulation-via-high-electrode-count-intrafascicular-peripheral-nerve-interface-after-brachial-plexus-injury
#12
Christopher C Duncan, David T Kluger, Tyler S Davis, David J Warren, David M Page, Douglas T Hutchinson, Gregory A Clark
OBJECTIVES: Kilohertz high-frequency alternating current (KHFAC) electrical nerve stimulation produces a reversible nerve block in peripheral nerves in human patients with chronic pain pathologies. Although this stimulation methodology has been verified with nonselective extrafascicular electrodes, the effectiveness of producing a selective nerve block with more-selective intrafascicular electrodes has not been well documented. The objective of this study was to examine whether intrafascicular electrodes can block painful stimuli while preserving conduction of other neural activity within the implanted nerve...
August 17, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/30102446/inhibition-of-experimental-tinnitus-with-high-frequency-stimulation-of-the-rat-medial-geniculate-body
#13
Gusta van Zwieten, Marcus L F Janssen, Jasper V Smit, A Miranda L Janssen, Milaine Roet, Ali Jahanshahi, Robert J Stokroos, Yasin Temel
BACKGROUND: Neuromodulation is a promising treatment modality for tinnitus, especially in chronic and severe cases. The auditory thalamus plays a key role in the pathophysiology of tinnitus, as it integrates and processes auditory and limbic information. OBJECTIVE: The effect of high frequency stimulation and low frequency stimulation of the medial geniculate bodies on tinnitus in a noise-induced tinnitus rat model is assessed. MATERIALS AND METHODS: Presence of tinnitus was verified using the gap-induced prepulse inhibition of the acoustic startle response paradigm...
August 13, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/30092121/removal-of-intrathecal-catheters-used-in-drug-delivery-systems
#14
Leonardo A Frizon, Navin C Sabharwal, Tanmoy Maiti, Joshua Golubovsky, Francis May, Jianning Shao, Andre G Machado, Sean J Nagel
INTRODUCTION: Implanted intrathecal drug delivery systems (IDDS) are increasingly used in the treatment of spasticity and in patients with refractory pain. Literature discussing complications associated with intrathecal pump placement is widely available. However, reports of complications following the removal of chronically placed catheters are scarce. We reviewed our series of patients who had surgery to remove the intrathecal catheter. METHODS: Retrospective review was performed for all patients who underwent surgery to remove a catheter linked to an IDDS between 2010 and 2016...
August 9, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/30085382/drg-focus-a-multicenter-study-evaluating-dorsal-root-ganglion-stimulation-and-predictors-for-trial-success
#15
Corey W Hunter, Dawood Sayed, Timothy Lubenow, Timothy Davis, Jonathan Carlson, Jeffery Rowe, Ralph Justiz, Tory McJunkin, Timothy Deer, Pankaj Mehta, Steven Falowski, Leo Kapural, Jason Pope, Nagy Mekhail
INTRODUCTION: Dorsal root ganglion stimulation (DRGS) is a powerful tool in the treatment of chronic, neuropathic pain. The premise of DRGS is similar to that of conventional spinal cord stimulation (cSCS), however, there is more variability in how it can be utilized. While it is this variability that likely gives it its versatility, DRGS is not as straightforward to implement as cSCS. The purpose of this study was to assess the efficacy of DRGS on a broad number of diagnoses, determine which dorsal root ganglia were associated with better outcomes for particular body parts/diagnoses, and evaluate what factors/parameters were associated with higher rates of trial success...
August 7, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/30079622/evaluating-dorsal-root-ganglion-stimulation-in-a-prospective-dutch-cohort
#16
Frank J P M Huygen, Liong Liem, Harold Nijhuis, William Cusack, Jeffery Kramer
OBJECTIVES: Dorsal root ganglion (DRG) stimulation is a recent neuromodulation option that has delivered safe, effective pain relief for a number of etiologies. This prospective observational study was intended to establish the effectiveness of this treatment in a typical real-world clinical context. MATERIALS AND METHODS: Participants with chronic, intractable pain of the trunk or lower limbs were recruited from multiple pain clinics in the Netherlands. Subjects were trialed and implanted with DRG stimulation systems...
August 5, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/30067887/dorsal-root-ganglion-stimulation-for-chronic-pelvic-pain-a-case-series-and-technical-report-on-a-novel-lead-configuration
#17
Corey W Hunter, Ajax Yang
INTRODUCTION: Chronic pelvic pain (CPP) is an elusive and complex neuropathic condition that is notoriously recalcitrant to treatment. The term "CPP" encompasses a number of treatment-resistant conditions like pudendal neuralgia, interstitial cystitis, coccygodynia, vulvodynia. CPP has been presented neuromodulators attempting to utilize conventional spinal cord stimulation (SCS), with constant frustration and high explant rates. Contrary to SCS, dorsal root ganglion stimulation (DRGS) delivers targeted target to focal areas, does not rely on paresthesias, and is able to reliably capture body parts like the pelvis making it an ideal modality for the treatment of CPP...
August 1, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/30024078/a-feasibility-study-of-percutaneous-peripheral-nerve-stimulation-for-the-treatment-of-postoperative-pain-following-total-knee-arthroplasty
#18
Brian M Ilfeld, Scott T Ball, Rodney A Gabriel, Jacklynn F Sztain, Amanda M Monahan, Wendy B Abramson, Bahareh Khatibi, Engy T Said, Jesal Parekh, Stuart A Grant, Amorn Wongsarnpigoon, Joseph W Boggs
INTRODUCTION: The objective of the present feasibility study was to investigate the use of a new treatment modality-percutaneous peripheral nerve stimulation (PNS)-in controlling the often severe and long-lasting pain following total knee arthroplasty (TKA). METHODS: For patients undergoing a primary, unilateral TKA, both femoral and sciatic open-coil percutaneous leads (SPR Therapeutics, Cleveland, OH) were placed up to seven days prior to surgery using ultrasound guidance...
July 19, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/30016006/behavioral-impact-of-long-term-chronic-implantation-of-neural-recording-devices-in-the-rhesus-macaque
#19
Colin T Kyle, Michele R Permenter, Julie A Vogt, Peter R Rapp, Carol A Barnes
BACKGROUND: Ensemble recording methods are pervasive in basic and clinical neuroscience research. Invasive neural implants are used in patients with drug resistant epilepsy to localize seizure origin, in neuropsychiatric or Parkinson's patients to alleviate symptoms via deep brain stimulation, and with animal models to conduct basic research. Studies addressing the brain's physiological response to chronic electrode implants demonstrate that the mechanical trauma of insertion is followed by an acute inflammatory response as well as a chronic foreign body response...
July 17, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/30015361/surgical-neuromodulation-of-tinnitus-a-review-of-current-therapies-and-future-applications
#20
REVIEW
Richard Rammo, Rushna Ali, Aqueel Pabaney, Michael Seidman, Jason Schwalb
INTRODUCTION: Tinnitus is the conscious perception of an auditory sensation in the absence of external stimulus. Proposed theories are based on neuroplastic changes that occur due to sensory deprivation. The authors review the relevant literature on functional imaging and neuromodulation of tinnitus and describe potential targets for deep brain stimulation (DBS). MATERIALS AND METHODS: A MEDLINE keyword and Medical Subject Heading term literature search was performed using PubMed for tinnitus, neuromodulation, DBS, transcranial magnetic stimulation, epidural electrode stimulation, intradural electrode stimulation, functional imaging, and connectivity...
July 17, 2018: Neuromodulation: Journal of the International Neuromodulation Society
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