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Computer Methods in Biomechanics and Biomedical Engineering

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https://www.readbyqxmd.com/read/28817976/an-open-source-model-and-solution-method-to-predict-co-contraction-in-the-finger
#1
Alexander R MacIntosh, Peter J Keir
A novel open-source biomechanical model of the index finger with an electromyography (EMG)-constrained static optimization solution method are developed with the goal of improving co-contraction estimates and providing means to assess tendon tension distribution through the finger. The Intrinsic model has four degrees of freedom and seven muscles (with a 14 component extensor mechanism). A novel plugin developed for the OpenSim modelling software applied the EMG-constrained static optimization solution method...
August 17, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28817960/effectiveness-of-pedicle-screw-inclusion-at-the-fracture-level-in-short-segment-fixation-constructs-for-the-treatment-of-thoracolumbar-burst-fractures-a-computational-biomechanics-analysis
#2
Shady Elmasry, Shihab Asfour, Francesco Travascio
When treating thoracolumbar burst fractures (BF), short-segment posterior fixation (SSPF) represents a less invasive alternative to the traditional long-segment posterior fixation (LSPF) approach. However, hardware failure and loss of sagittal alignment have been reported in patients treated with SSPF. Including pedicle screws at the fracture level in SSPF constructs has been proposed to improve stiffness and reliability of the construct. Accordingly, the biomechanical performance of the proposed construct was compared to LSPF via a computational analysis...
August 17, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28812366/a-combination-of-experimental-measurement-constitutive-damage-model-and-diffusion-tensor-imaging-to-characterize-the-mechanical-properties-of-the-human-brain
#3
Alireza Karimi, Seyed Mohammadali Rahmati, Reza Razaghi
Understanding the mechanical properties of the human brain is deemed important as it may subject to various types of complex loadings during the Traumatic Brain Injury (TBI). Although many studies so far have been conducted to quantify the mechanical properties of the brain, there is a paucity of knowledge on the mechanical properties of the human brain tissue and the damage of its axon fibers under the various types of complex loadings during the Traumatic Brain Injury (TBI). Although many studies so far have been conducted to quantify the mechanical properties of the brain, there is a paucity of knowledge on the mechanical properties of the human brain tissue and the damage of its axon fibers under the frontal lobe of the human brain...
August 16, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28793805/fatigue-failure-of-the-sliding-hip-screw-clinical-and-biomechanical-analysis
#4
Libor Necas, Maros Hrubina, Zoltan Cibula, Jiri Behounek, Stanislav Krivanek, Zdenek Horak
The study was aimed at the clinical and biomechanical analyses of the sliding hip screw breakage with the use of finite element method. We have identified two patients with the sliding screw breakage. In the first patient, the biomechanical analysis revealed the reduced stress values σHMH not exceeding the yield limit or strength limit of the implant. The yield limit was exceeded in second one. Clinical and biomechanical analyses have demonstrated that adherence to technical requirements of the appropriate osteosynthesis implementation is the principal condition of timely healing since it prevents the material failure...
August 9, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28782386/glottis-effects-on-the-cough-clearance-process-simulated-with-a-cfd-dynamic-mesh-and-eulerian-wall-film-model
#5
Concepción Paz, Eduardo Suárez, Oscar Parga, Jesús Vence
In this study, we have reproduced the cough clearance process with an Eulerian wall film model. The simulated domain is based on realistic geometry from the literature, which has been improved by adding the glottis and epiglottis. The vocal fold movement has been included due to the dynamic mesh method, considering different abduction and adduction angles and velocities. The proposed methodology captures the deformation of the flexible tissue, considers non-Newtonian properties for the mucus, and enables us to reproduce a single cough or a cough epoch...
August 7, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28768423/biomechanical-comparison-of-conventional-and-optimised-locking-plates-for-the-fixation-of-intraarticular-calcaneal-fractures-a-finite-element-analysis
#6
Hanbin Ouyang, Yuping Deng, Pusheng Xie, Yang Yang, Bingyun Jiang, Canjun Zeng, Wenhua Huang
Intraarticular calcaneal fractures can result in poor prognosis. Although operative fixation can improve the functional outcomes in most cases, surgical complications such as loss of reduction and wound healing problems may increase the risk of reoperation. Hence, this study aimed to design calcaneal locking plate with a lower profile and better biomechanical performance   and to compare the redesigned plate with the traditional calcaneal plate via the finite element method. A Sanders' type II-C intraarticular calcaneal fracture was simulated...
August 3, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28768422/influence-of-anisotropic-bone-properties-on-the-biomechanical-behavior-of-the-acetabular-cup-implant-a-multiscale-finite-element-study
#7
Vu-Hieu Nguyen, Giuseppe Rosi, Salah Naili, Adrien Michel, Maria-Letizia Raffa, Romain Bosc, Jean-Paul Meningaud, Christine Chappard, Naoki Takano, Guillaume Haiat
Although the biomechanical behavior of the acetabular cup (AC) implant is determinant for the surgical success, it remains difficult to be assessed due to the multiscale and anisotropic nature of bone tissue. The aim of the present study was to investigate the influence of the anisotropic properties of peri-implant trabecular bone tissue on the biomechanical behavior of the AC implant at the macroscopic scale. Thirteen bovine trabecular bone samples were imaged using micro-computed tomography (μCT) with a resolution of 18 μm...
August 3, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28730879/rgrna-prediction-of-rna-secondary-structure-based-on-replacement-and-growth-of-stems
#8
Jin Li, Chengzhen Xu, Hong Liang, Wang Cong, Ying Wang, Kuan Luan, Yunlong Liu
Owing to their structural diversity, RNAs perform many diverse biological functions in the cell. RNA secondary structure is thus important for predicting RNA function. Here, we propose a new combinatorial optimization algorithm, named RGRNA, to improve the accuracy of predicting RNA secondary structure. Following the establishment of a stempool, the stems are sorted by length, and chosen from largest to smallest. If the stem selected is the true stem, the secondary structure of this stem when combined with another stem selected at random will have low free energy, and the free energy will tend to gradually diminish...
July 21, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28701050/validation-performance-comparison-for-finite-element-models-of-the-human-brain
#9
Logan E Miller, Jillian E Urban, Joel D Stitzel
The objective of this study was to compare the performance of six validated brain finite element (FE) models to localized brain motion validation data in five experimental configurations. Model performance was measured using the objective metric CORA (CORrelation and Analysis), where higher ratings represent better correlation. The KTH model achieved the highest average CORA rating, and the ABM received the highest average rating among models robustly validated against five cadaver impacts in three directions...
July 12, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28699356/a-kinect-based-movement-assessment-system-marker-position-comparison-to-vicon
#10
Julia K Nichols, Mark P Sena, Jennifer L Hu, Oliver M O'Reilly, Brian T Feeley, Jeffrey C Lotz
Accurate movement analysis systems are prohibitive in cost and size to be accessible to the general population, while commercially available, affordable systems lack the accuracy needed for clinical relevance. To address these limitations, we developed a Depth Camera Movement Assessment System (DCMAS) featuring an affordable, widely available depth camera (e.g. Microsoft Kinect). After examining 3D position data for markers adhered to participants and a flat surface, captured with both DCMAS and the industry standard Vicon system, we demonstrated DCMAS obtained measurements comparable, within soft tissue artifact, to the Vicon system, paving the way for a breakthrough technology in preventative medicine...
July 12, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28685612/protective-capacity-of-an-ice-hockey-goaltender-helmet-for-three-events-associated-with-concussion
#11
J Michio Clark, T Blaine Hoshizaki, Michael D Gilchrist
The purpose of this study was to assess the protective capacity of an ice hockey goaltender helmet for three concussive impact events. A helmeted and unhelmeted headform was used to test three common impact events in ice hockey (fall, puck impacts and shoulder collisions). Peak linear acceleration, rotational acceleration and rotational velocity as well as maximum principal strain and von Mises stress were measured for each impact condition. The results demonstrated the tested ice hockey goaltender helmet was well designed to manage fall and puck impacts but does not consistently protect against shoulder collisions and an opportunity may exist to improve helmet designs to better protect goaltenders from shoulder collisions...
July 7, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28678541/mechanical-role-of-a-growing-solid-tumor-on-cortical-folding
#12
Mir Jalil Razavi, Mary Reeves, Xianqiao Wang
Cortical folding, or convolution of the brain, is a vital process in mammals that causes the brain to have a wrinkled appearance. The existence of different types of prenatal solid tumors may alter this complex phenomenon and cause severe brain disorders. Here we interpret the effects of a growing solid tumor on the cortical folding in the fetal brain by virtue of theoretical analyses and computational modeling. The developing fetal brain is modeled as a simple, double-layered, and soft structure with an outer cortex and an inner core, in combination with a circular tumor model imbedded in the structure to investigate the developmental mechanism of cortical convolution...
July 5, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28675049/importance-of-material-parameters-and-strain-energy-function-on-the-wall-stresses-in-the-left-ventricle
#13
Sareh Behdadfar, Laurent Navarro, Joakim Sundnes, Molly M Maleckar, Stéphane Avril
Patient-specific estimates of the stress distribution in the left ventricles (LV) may have important applications for therapy planning, but computing the stress generally requires knowledge of the material behaviour. The passive stress-strain relation of myocardial tissue has been characterized by a number of models, but material parameters (MPs) remain difficult to estimate. The aim of this study is to implement a zero-pressure algorithm to reconstruct numerically the stress distribution in the LV without precise knowledge of MPs...
July 4, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28675048/biomechanical-causes-of-trapeziometacarpal-arthroplasty-failure
#14
V Spartacus, A Mayoly, A Gay, T Le Corroller, M Némoz-Gaillard, S Roffino, P Chabrand
Trapeziometacarpal joint prosthesis revision has been widely reported, mainly due to loosening of the trapezium cup. Our hypothesis is that current prostheses do not sufficiently respect the kinematics of this joint. CT scan acquisitions enabled us to determine the position of the first metacarpal relative to the trapezium in three different characteristic postures, in subjects in different stages of arthrosis. A CAD model of a current prosthesis was inserted into the numerical 3D model of the joint under the different postures...
July 4, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28675043/effect-of-round-curvature-of-anterior-implant-supported-zirconia-frameworks-finite-element-analysis-and-in-vitro-study-using-digital-image-correlation
#15
Ana Messias, Maria Augusta Neto, Ana Martins Amaro, Pedro Nicolau, Luis Manuel Roseiro
Two groups of 4-unit zirconia frameworks were produced by CAD/CAM to simulate the restoration of an anterior edentulous gap supported by 2 implant-abutment assemblies. Group 1 comprised straight configuration frameworks and group 2 consisted of arched frameworks. Specimens were made with the same connector cross-section area and were cemented and submitted to static loads. Displacements were captured with two high-speed photographic cameras and analysed with video correlation system. Frameworks and the implant-abutment assembly were scanned and converted to 3DCAD objects by reverse engineering process...
July 4, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28658586/small-bubble-transport-and-splitting-dynamics-in-a-symmetric-bifurcation
#16
Adnan Qamar, Matthew Warnez, Doug T Valassis, Megan E Guetzko, Joseph L Bull
Simulations of small bubbles traveling through symmetric bifurcations are conducted to garner information pertinent to gas embolotherapy, a potential cancer treatment. Gas embolotherapy procedures use intra-arterial bubbles to occlude tumor blood supply. As bubbles pass through bifurcations in the blood stream nonhomogeneous splitting and undesirable bioeffects may occur. To aid development of gas embolotherapy techniques, a volume of fluid method is used to model the splitting process of gas bubbles passing through artery and arteriole bifurcations...
June 28, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28650686/the-influence-of-limb-alignment-and-transfemoral-amputation-technique-on-muscle-capacity-during-gait
#17
Ellyn C Ranz, Jason M Wilken, Donald A Gajewski, Richard R Neptune
Many factors influence successful outcomes following transfemoral amputation. One factor is surgical technique. In this study, the influence of limb alignment and surgical technique on a muscle's capacity to generate force was examined using musculoskeletal modeling. Non-amputee and transfemoral amputee models were analyzed while hip adduction, femur length, and reattached muscle wrap position, tension and stabilization technique were systematically varied. With muscle tension preserved, wrap position and femur length had little influence on muscle capacity...
June 26, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28632407/prediction-of-the-structural-response-of-the-femoral-shaft-under-dynamic-loading-using-subject-specific-finite-element-models
#18
Gwansik Park, Taewung Kim, Jason Forman, Matthew B Panzer, Jeff R Crandall
The goal of this study was to predict the structural response of the femoral shaft under dynamic loading conditions using subject-specific finite element (SS-FE) models and to evaluate the prediction accuracy of the models in relation to the model complexity. In total, SS-FE models of 31 femur specimens were developed. Using those models, dynamic three-point bending and combined loading tests (bending with four different levels of axial compression) of bare femurs were simulated, and the prediction capabilities of five different levels of model complexity were evaluated based on the impact force time histories: baseline, mass-based scaled, structure-based scaled, geometric SS-FE, and heterogenized SS-FE models...
June 20, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28628751/comparison-between-line-and-surface-mesh-models-to-represent-the-rotator-cuff-muscle-geometry-in-musculoskeletal-models
#19
Marion Hoffmann, Diane Haering, Mickaël Begon
Accurate muscle geometry (muscle length and moment arm) is required to estimate muscle function when using musculoskeletal modelling. In shoulder, muscles are often modelled as a collection of independent line segments, leading to non-physiological muscles trajectory, especially for the rotator cuff muscles. To prevent this, a surface mesh model was developed and validated against 7 MRI positions in one participant. Mean moment arm errors was 11.4% for the line vs. 8.8% for the mesh model. While the model with independent lines led to some non-physiological trajectories, the mesh model gave lower misestimations of muscle lengths and moment arms...
June 19, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28631937/the-effect-of-the-sagittal-ridge-angle-on-cartilage-stress-in-the-equine-metacarpo-phalangeal-fetlock-joint
#20
Helen Liley, Helen Davies, Elwyn Firth, Thor Besier, Justin Fernandez
Fatigue failure of bones of the metacarpo-phalangeal (fetlock, MCP) joint is common in thoroughbred racehorses. Stresses within the fetlock joint cartilages are affected by the morphology of the third metacarpal bone (MC3) and proximal phalangeal bone, and the steepness of the median sagittal ridge of MC3 is believed to be associated with fracture. This study investigated the influence of the steepness of the sagittal ridge on cartilage stress distribution using a finite element model of the joint. Changes to the steepness of the sagittal ridge were made by applying a parabolic function to the mesh, creating four different models with sagittal ridge angles ranging from 95° to 105°...
June 15, 2017: Computer Methods in Biomechanics and Biomedical Engineering
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