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Computer Methods in Biomechanics and Biomedical Engineering

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https://www.readbyqxmd.com/read/28090780/a-multi-body-dynamics-study-on-a-weight-drop-test-of-rat-brain-injury
#1
Wenyi Yan, Germain Sossou, Ramesh Rajan
Traumatic brain injury (TBI), induced by impact of an object with the head, is a major health problem worldwide. Rats are a well-established animal analogue for study of TBI and the weight-drop impact-acceleration (WDIA) method is a well-established model in rats for creating diffuse TBI, the most common form of TBI seen in humans. However, little is known of the biomechanics of the WDIA method and, to address this, we have developed a four-degrees-of-freedom multi-body mass-spring-damper model for the WDIA test in rats...
January 16, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28024426/across-subject-calibration-of-an-instrumented-glove-to-measure-hand-movement-for-clinical-purposes
#2
Verónica Gracia-Ibáñez, Margarita Vergara, James H Buffi, Wendy M Murray, Joaquín L Sancho-Bru
Motion capture of all degrees of freedom of the hand collected during performance of daily living activities remains challenging. Instrumented gloves are an attractive option because of their higher ease of use. However, subject-specific calibration of gloves is lengthy and has limitations for individuals with disabilities. Here, a calibration procedure is presented, consisting in the recording of just a simple hand position so as to allow capture of the kinematics of 16 hand joints during daily life activities even in case of severe injured hands...
December 27, 2016: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/27998170/accuracy-of-femur-reconstruction-from-sparse-geometric-data-using-a-statistical-shape-model
#3
Ju Zhang, Thor F Besier
Sparse geometric information from limited field-of-view medical images is often used to reconstruct the femur in biomechanical models of the hip and knee. However, the full femur geometry is needed to establish boundary conditions such as muscle attachment sites and joint axes which define the orientation of joint loads. Statistical shape models have been used to estimate the geometry of the full femur from varying amounts of sparse geometric information. However, the effect that different amounts of sparse data have on reconstruction accuracy has not been systematically assessed...
December 21, 2016: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/27957883/virtual-anatomical-reconstruction-of-large-acetabular-bone-defects-using-a-statistical-shape-model
#4
Peter Vanden Berghe, Jan Demol, Frederik Gelaude, Jos Vander Sloten
Custom implants are used to treat patients with large acetabular bone defects. To quantify the bone defect and to initialize the implant design, a virtual anatomical reconstruction of the bone needs to be performed. Our SSM-based reconstruction approach was used to overcome the limitations of the mirrored contralateral method and improves upon other SSM reconstruction techniques. The reconstruction errors for the acetabular direction, the hip joint center and the acetabular radius were, respectively: [Formula: see text], 2...
December 13, 2016: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/27957877/a-case-for-poroelasticity-in-skeletal-muscle-finite-element-analysis-experiment-and-modeling
#5
Benjamin B Wheatley, Gregory M Odegard, Kenton R Kaufman, Tammy L Haut Donahue
Finite element models of skeletal muscle typically ignore the biphasic nature of the tissue, associating any time dependence with a viscoelastic formulation. In this study, direct experimental measurement of permeability was conducted as a function of specimen orientation and strain. A finite element model was developed to identify how various permeability formulations affect compressive response of the tissue. Experimental and modeling results suggest the assumption of a constant, isotropic permeability is appropriate...
December 13, 2016: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/27887036/customized-mandibular-reconstruction-plates-improve-mechanical-performance-in-a-mandibular-reconstruction-model
#6
Ralf Gutwald, Raimund Jaeger, Floor M Lambers
The purpose of this paper was to analyze the biomechanical performance of customized mandibular reconstruction plates with optimized strength. The best locations for increasing bar widths were determined with a sensitivity analysis. Standard and customized plates were mounted on mandible models and mechanically tested. Maximum stress in the plate could be reduced from 573 to 393 MPa (-31%) by increasing bar widths. The median fatigue limit was significantly greater (p < 0.001) for customized plates (650 ± 27 N) than for standard plates (475 ± 27 N)...
November 25, 2016: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/27873535/loading-of-the-lumbar-spine-during-backpack-carriage
#7
Patrick D Wettenschwiler, Silvio Lorenzetti, Stephen J Ferguson, Rolf Stämpfli, Ameet K Aiyangar, René M Rossi, Simon Annaheim
Backpack carriage is significantly associated with a higher prevalence of low back pain. Elevated compression and shear forces in the lumbar intervertebral discs are known risk factors. A novel method of calculating the loads in the lumbar spine during backpack carriage is presented by combining physical and numerical modelling. The results revealed that to predict realistic lumbar compression forces, subject-specific lumbar curvature data were not necessary for loads up to 40 kg. In contrast, regarding shear forces, using subject-specific lumbar curvature data from upright MRI measurements as input for the rigid body model significantly altered lumbar joint force estimates...
November 22, 2016: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/27868425/real-time-simulation-of-hand-motion-for-prosthesis-control
#8
Dimitra Blana, Edward K Chadwick, Antonie J van den Bogert, Wendy M Murray
Individuals with hand amputation suffer substantial loss of independence. Performance of sophisticated prostheses is limited by the ability to control them. To achieve natural and simultaneous control of all wrist and hand motions, we propose to use real-time biomechanical simulation to map between residual EMG and motions of the intact hand. Here we describe a musculoskeletal model of the hand using only extrinsic muscles to determine whether real-time performance is possible. Simulation is 1.3 times faster than real time, but the model is locally unstable...
November 20, 2016: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/27848266/sensitivity-of-lumbar-spine-response-to-follower-load-and-flexion-moment-finite-element-study
#9
Sadegh Naserkhaki, Marwan El-Rich
The follower load (FL) combined with moments is commonly used to approximate flexed/extended posture of the lumbar spine in absence of muscles in biomechanical studies. There is a lack of consensus as to what magnitudes simulate better the physiological conditions. Considering the in-vivo measured values of the intradiscal pressure (IDP), intervertebral rotations (IVRs) and the disc loads, sensitivity of these spinal responses to different FL and flexion moment magnitudes was investigated using a 3D nonlinear finite element (FE) model of ligamentous lumbosacral spine...
November 16, 2016: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/27838925/on-the-assessment-of-bridging-vein-rupture-associated-acute-subdural-hematoma-through-finite-element-analysis
#10
Zhao Ying Cui, Nele Famaey, Bart Depreitere, Jan Ivens, Svein Kleiven, Jos Vander Sloten
Acute subdural hematoma (ASDH) is a type of intracranial haemorrhage following head impact, with high mortality rates. Bridging vein (BV) rupture is a major cause of ASDH, which is why a biofidelic representation of BVs in finite element (FE) head models is essential for the successful prediction of ASDH. We investigated the mechanical behavior of BVs in the KTH FE head model. First, a sensitivity study quantified the effect of loading conditions and mechanical properties on BV strain. It was found that the peak rotational velocity and acceleration and pulse duration have a pronounced effect on the BV strains...
November 14, 2016: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/27832709/a-model-of-neurovascular-coupling-and-the-bold-response-part-i
#11
E J Mathias, M J Plank, T David
The mechanisms with which neurons communicate with the vasculature to increase blood flow, termed neurovascular coupling is still unclear primarily due to the complex interactions between many parameters and the difficulty in accessing, monitoring and measuring them in the highly heterogeneous brain. Hence a solid theoretical framework based on existing experimental knowledge is necessary to study the relation between neural activity, the associated vasoactive factors released and their effects on the vasculature...
November 11, 2016: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/27832702/a-model-of-neurovascular-coupling-and-the-bold-response-part-ii
#12
E J Mathias, M J Plank, T David
A mathematical model is developed which describes a signalling mechanism of neurovascular coupling with a model of a pyramidal neuron and its corresponding fMRI BOLD response. In the first part of two papers (Part I) we described the integration of the neurovascular coupling unit extended to include a complex neuron model, which includes the important Na/K ATPase pump, with a model that provides a BOLD signal taking its input from the cerebral blood flow and the metabolic rate of oxygen consumption. We showed that this produced a viable signal in terms of initial dip, positive and negative BOLD signals...
November 11, 2016: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/27802781/blood-flow-in-the-cerebral-venous-system-modeling-and-simulation
#13
Olivia Miraucourt, Stéphanie Salmon, Marcela Szopos, Marc Thiriet
The development of a software platform incorporating all aspects, from medical imaging data, through three-dimensional reconstruction and suitable meshing, up to simulation of blood flow in patient-specific geometries, is a crucial challenge in biomedical engineering. In the present study, a fully three-dimensional blood flow simulation is carried out through a complete rigid macrovascular circuit, namely the intracranial venous network, instead of a reduced order simulation and partial vascular network. The biomechanical modeling step is carefully analyzed and leads to the description of the flow governed by the dimensionless Navier-Stokes equations for an incompressible viscous fluid...
November 1, 2016: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/27800698/on-the-importance-of-3d-geometrically-accurate-and-subject-specific-finite-element-analysis-for-evaluation-of-in-vivo-soft-tissue-loads
#14
Kevin M Moerman, Marc van Vijven, Leandro R Solis, Eline E van Haaften, Arjan C Y Loenen, Vivian K Mushahwar, Cees W J Oomens
Pressure ulcers are a type of local soft tissue injury due to sustained mechanical loading and remain a common issue in patient care. People with spinal cord injury (SCI) are especially at risk of pressure ulcers due to impaired mobility and sensory perception. The development of load improving support structures relies on realistic tissue load evaluation e.g. using finite element analysis (FEA). FEA requires realistic subject-specific mechanical properties and geometries. This study focuses on the effect of geometry...
November 1, 2016: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/27796137/two-dimensional-intraventricular-flow-pattern-visualization-using-the-image-based-computational-fluid-dynamics
#15
Siamak N Doost, Liang Zhong, Boyang Su, Yosry S Morsi
The image-based computational fluid dynamics (IB-CFD) technique, as the combination of medical images and the CFD method, is utilized in this research to analyze the left ventricle (LV) hemodynamics. The research primarily aims to propose a semi-automated technique utilizing some freely available and commercial software packages in order to simulate the LV hemodynamics using the IB-CFD technique. In this research, moreover, two different physiological time-resolved 2D models of a patient-specific LV with two different types of aortic and mitral valves, including the orifice-type valves and integrated with rigid leaflets, are adopted to visualize the process of developing intraventricular vortex formation and propagation...
October 31, 2016: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28095721/a-lateral-dynamics-of-a-wheelchair-identification-and-analysis-of-tire-parameters
#16
L C A Silva, F C Corrêa, J J Eckert, F M Santiciolli, F G Dedini
In vehicle dynamics studies, the tire behaviour plays an important role in planar motion of the vehicle. Therefore, a correct representation of tire is a necessity. This paper describes a mathematical model for wheelchair tire based on the Magic Formula model. This model is widely used to represent forces and moments between the tire and the ground; however some experimental parameters must be determined. The purpose of this work is to identify the tire parameters for the wheelchair tire model, implementing them in a dynamic model of the wheelchair...
February 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/27899027/corrigendum
#17
(no author information available yet)
No abstract text is available yet for this article.
February 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/27873534/corrigendum
#18
(no author information available yet)
No abstract text is available yet for this article.
February 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/27635796/a-poroelastic-finite-element-model-of-the-bone-cartilage-unit-to-determine-the-effects-of-changes-in-permeability-with-osteoarthritis
#19
Michael E Stender, Richard A Regueiro, Virginia L Ferguson
The changes experienced in synovial joints with osteoarthritis involve coupled chemical, biological, and mechanical processes. The aim of this study was to investigate the consequences of increasing permeability in articular cartilage (AC), calcified cartilage (CC), subchondral cortical bone (SCB), and subchondral trabecular bone (STB) as observed with osteoarthritis. Two poroelastic finite element models were developed using a depth-dependent anisotropic model of AC with strain-dependent permeability and poroelastic models of calcified tissues (CC, SCB, and STB)...
February 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/27609339/accommodation-of-the-human-lens-capsule-using-a-finite-element-model-based-on-nonlinear-regionally-anisotropic-biomembranes
#20
G David, R M Pedrigi, J D Humphrey
Accommodation of the eyes, the mechanism that allows humans to focus their vision on near objects, naturally diminishes with age via presbyopia. People who have undergone cataract surgery, using current surgical methods and artificial lens implants, are also left without the ability to accommodate. The process of accommodation is generally well known; however the specific mechanical details have not been adequately explained due to difficulties and consequences of performing in vivo studies. Most studies have modeled the mechanics of accommodation under assumptions of a linearly elastic, isotropic, homogenous lens and lens capsule...
February 2017: Computer Methods in Biomechanics and Biomedical Engineering
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