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International Journal of Clinical Practice

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https://www.readbyqxmd.com/read/28318076/uk-policy-statements-on-testosterone-deficiency
#1
Geoffrey Hackett, Michael Kirby, David Edwards, T Hugh Jones, Jonathan Rees, Asif Muneer
To address widespread media and scientific concerns over the appropriate treatment of TDS with Testosterone Therapy (T Therapy), the Executive Committee of the British Society for Sexual Medicine developed eight consensus statements, based on current scientific evidence to address these controversial issues. These statements were in no-way designed to replace the published evidence-based guidelines on the subject developed by various professional organisations, but to provide specific answers to several current controversial issues...
March 20, 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28276182/application-of-the-national-early-warning-score-news-as-a-stratification-tool-on-admission-in-an-italian-acute-medical-ward-a-perspective-study
#2
Walter Spagnolli, Marta Rigoni, Emanuele Torri, Susanna Cozzio, Elisa Vettorato, Giandomenico Nollo
AIM: We aimed to assess the performance of the National Early Warning Score (NEWS) as tool for patient risk stratification at admission in an acute Internal Medicine ward and to ensure patient placement in ward areas with the required and most appropriate intensity of care. As secondary objective, we considered NEWS performance in two subgroups of patients: sudden cardiac events (acute coronary syndromes and arrhythmic events), and chronic respiratory insufficiency. METHODS: We conducted a perspective cohort single centre study on 2,677 unselected patients consecutively admitted from July 2013 to March 2015 in the Internal Medicine ward of the hospital of Trento, Italy...
March 9, 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28150372/coexistent-malignant-conditions-in-rheumatoid-arthritis-a-population-based-cross-sectional-study
#3
Amir Dagan, Gad Segal, Shmuel Tiosano, Abdulla Watad, Shana G Neumann, Doron Comaneshter, Arnon D Cohen, Howard Amital
OBJECTIVES: The aim of this study was to evaluate if association exist between rheumatoid arthritis and malignant diseases. METHODS: A cross-sectional study was conducted comparing rheumatoid arthritis patients with age and gender matched controls regarding the proportion of patients with comorbid malignant conditions. Chi-square tests and t-tests were used for univariate analysis. A logistic regression model was used for multivariate analysis. The study was performed utilising the medical database of Clalit Health Services...
February 1, 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28238231/what-to-watch-in-medicine-in-2017-hot-topics
#4
EDITORIAL
Leslie Citrome
No abstract text is available yet for this article.
February 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28238230/corrigendum
#5
(no author information available yet)
No abstract text is available yet for this article.
February 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28238229/suspecting-non-cystic-fibrosis-bronchiectasis-what-the-busy-primary-care-clinician-needs-to-know
#6
REVIEW
Diego J Maselli, Bravein Amalakuhan, Holly Keyt, Alejandro A Diaz
AIMS: Non-cystic fibrosis bronchiectasis (NCFB) is a chronic, progressive respiratory disorder characterised by irreversibly and abnormally dilated airways, persistent cough, excessive sputum production and recurrent pulmonary infections. In the last several decades, its prevalence has increased, making it likely to be encountered in the primary care setting. The aim was to review the clinical presentation and diagnosis of NCFB, with an emphasis on the role of computed tomography (CT)...
February 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28238228/is-sedentary-behaviour-unhealthy-and-if-so-does-reducing-it-improve-this
#7
REVIEW
Shao-Hua Chin, Chanaka Kahathuduwa, Martin Binks
PURPOSE: To provide a qualitative synthesis of the available literature on the role of sedentary behavior in health. AIMS: We sought to determine if (i) being sedentary 'causes' health problems and (ii) interventions to reduce sedentary behavior improve health status. METHODS: PubMed and Google Scholar databases were utilized. Manuscripts published from 2001 to 2015 using specific keyword combinations (eg sedentary behavior, physical activity, sitting, intervention) were included and qualitatively reviewed...
February 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28238227/hopes-and-challenges-for-the-common-cold
#8
EDITORIAL
Richard A Stein
No abstract text is available yet for this article.
February 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28090727/italian-patients-with-more-recent-onset-of-major-depressive-disorder-have-a-shorter-duration-of-untreated-illness
#9
Bernardo Dell'Osso, Laura Cremaschi, Benedetta Grancini, Francesca De Cagna, Beatrice Benatti, Giulia Camuri, Chiara Arici, Cristina Dobrea, Lucio Oldani, Maria Carlotta Palazzo, Matteo Vismara, A Carlo Altamura
BACKGROUND: Previous investigation on the duration of untreated illness (DUI) in patients with Major Depressive Disorder (MDD) revealed a different latency to first antidepressant treatment, with adverse consequences in terms of outcome for individuals with a longer DUI. Recent reports, moreover, documented a reduced DUI, as observed with the passage of time, in patients with different psychiatric disorders. Hence, the present study was aimed to assess DUI and related variables in a sample of Italian patients with MDD as well as to investigate potential differences in subjects with onset before and after 2000...
February 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28090718/an-analysis-of-policies-for-cotrimoxazole-amoxicillin-and-azithromycin-use-in-namibia-s-public-sector-findings-and-therapeutic-implications
#10
Dan Kibuule, Mwangana Mubita, Ester Naikaku, Francis Kalemeera, Brian B Godman, Evans Sagwa
BACKGROUND: Despite Namibia's robust medicine use systems and policies, antibiotic use indicators remain suboptimal. Recent medicine use surveys rank cotrimoxazole, amoxicillin and azithromycin (CAA) among the most used medicines. However, there is rising resistance to CAA (55.9%-96.7%). Unfortunately, to date, there have been limited studies evaluating policies to improve antibiotic use in Namibia. AIM: To evaluate public sector pharmaceutical policies and guidelines influencing the therapeutic use of CAA antibiotics in Namibia...
February 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28074617/soft-drink-intake-and-the-risk-of-metabolic-syndrome-a%C3%A2-systematic-review-and-meta-analysis
#11
REVIEW
Aditya Narain, Chun Shing Kwok, Mamas A Mamas
BACKGROUND: It is unclear whether consumption of sugar- or artificially sweetened beverages is independently associated with the development of metabolic syndrome. A systematic review and meta-analysis was performed to evaluate whether soft drink consumption is associated with the development of metabolic syndrome. METHODS: Medline and EMBASE were searched in November 2015 for studies which considered soft drink (sugar-sweetened beverage [SSB] and artificially sweetened beverage [ASB]) intake and risk of metabolic syndrome...
February 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/27925348/factors-associated-with-efficacy-of-an-ibuprofen-pseudoephedrine-combination-drug-in-pharmacy-customers%C3%A2-with-common-cold-symptoms
#12
Ludger Klimek, Helmut Schumacher, Tanja Schütt, Heidemarie Gräter, Tobias Mueck, Martin C Michel
AIM: The aim of this study was to explore factors affecting efficacy of treatment of common cold symptoms with an over-the-counter ibuprofen/pseudoephedrine combination product. METHODS: Data from an anonymous survey among 1770 pharmacy customers purchasing the combination product for treatment of own common cold symptoms underwent post-hoc descriptive analysis. Scores of symptoms typically responsive to ibuprofen (headache, pharyngeal pain, joint pain and fever), typically responsive to pseudoephedrine (congested nose, congested sinus and runny nose), considered non-specific (sneezing, fatigue, dry cough, cough with expectoration) and comprising all 11 symptoms were analysed...
February 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28097763/monitoring-thyroid-function-in-patients-on-levothyroxine-audit-findings-and-suggested-change-in-practice
#13
LETTER
Jonathan J Scargill, Mark Livingston, David Holland, Adnan Khan, Christopher J Duff, Anthony A Fryer, Adrian H Heald
No abstract text is available yet for this article.
January 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28097762/time-delays-in-the-diagnosis-and-treatment-of-fabry-disease
#14
Ricardo Reisin, Amandine Perrin, Pablo García-Pavía
BACKGROUND: The high variability in clinical manifestations of Fabry disease can lead to delays between symptom onset and correct diagnosis, and between correct diagnosis and initiation of enzyme replacement therapy. We investigated whether these delays have improved in recent years. METHODS: Data were analysed from the Fabry Outcome Survey (FOS; Shire; extracted August 2013) for "index patients", defined as the first patient diagnosed with Fabry disease from a family with several or no additional members registered in FOS...
January 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28097761/shortened-hospital-length-of-stay-and-lower-costs-associated-with-rivaroxaban-in-patients-with-pulmonary-embolism-managed-as-observation-status
#15
Erin R Weeda, W Frank Peacock, Gregory J Fermann, Christopher W Baugh, Philip S Wells, Veronica Ashton, Concetta Crivera, Peter Wildgoose, Jeff R Schein, Craig I Coleman
BACKGROUND: Unlike rivaroxaban, treatment of patients with pulmonary embolism (PE) with warfarin requires parenteral bridging and coagulation monitoring that may prolong length-of-stay (LOS) and increase hospital costs. AIMS: The aim of this study was to compare LOS, hospital costs and readmissions in PE patients managed through observation stays treated with rivaroxaban or parenterally bridged warfarin. METHODS: Premier Hospital claims data from November 2012 to March 2015 were used to identify patients with a primary diagnosis code for PE managed through an observation stay and with ≥1 claim for a PE-related diagnostic test on day 0-2...
January 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28097760/benefits-of-quitting-smoking-on-work-productivity-and-activity-impairment-in-the-united-states-the-european-union-and-china
#16
Christine L Baker, Natalia M Flores, Kelly H Zou, Marianna Bruno, Vannessa J Harrison
BACKGROUND: Smoking has important health and economic consequences for individuals and society. This study expands the understanding of work-related burden associated with smoking and benefit of smoking cessation across the US, European Union (EU) and China using large-scale, representative survey methodology. METHODS: Data utilised the 2013 National Health and Wellness Survey in United States (US), EU5 (UK, France, Germany, Italy, and Spain) and China. Working-aged respondents 18-64 were used in the analyses (US N=58 500; EU5 N=50 417; China N=17 987) and were categorised into: current smokers, trying to quit, former smokers and never smokers...
January 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28097759/our-digital-world-goodbye-pagination-hello-elocators
#17
EDITORIAL
Leslie Citrome
No abstract text is available yet for this article.
January 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28097758/alpha-blockers-in-the-management-of-ureteric-lithiasis-a-meta-analysis
#18
Nicholas Raison, Kamran Ahmed, Oliver Brunckhorst, Prokar Dasgupta
INTRODUCTION: Effective medical expulsion for ureteric stones with α-blockers offers numerous advantages over surgical alternatives. However, its effectiveness remains uncertain and with the publication of new trial data, the available evidence requires reappraisal. OBJECTIVE: The aim of this study was to assess the efficacy of α-blockers the management of ureteric lithiasis. METHODS: A systematic review of the literature, with predefined search criteria, was conducted using PubMed and Embase...
January 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/27981681/development-and-validation-of-prescribing-quality-indicators-for-patients-with-type-2-diabetes
#19
Kirsten P J Smits, Grigory Sidorenkov, Nanno Kleefstra, Margriet Bouma, Marianne Meulepas, Jaco Voorham, Gerjan Navis, Henk J G Bilo, Petra Denig
AIM: Quality indicators are used to measure whether healthcare professionals act according to guidelines, but few indicators focus on the quality of pharmacotherapy for diabetes. The aim of this study was to develop and validate a set of prescribing quality indicators (PQIs) for type 2 diabetes in primary care, and to apply this set in practice. To take into account the stepwise treatment of chronic disease, clinical action indicators were specifically considered. METHODS: Potential PQIs were derived from clinical practice guidelines and evaluated using the RAND/UCLA Appropriateness Method, a modified Delphi panel...
January 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/27933734/improved-quality-of-life-in-asthma-patients-under-long-term-therapy-assessed-by-ahq-japan
#20
Yuji Tohda, Takashi Iwanaga, Hiroyuki Sano, Hiroaki Kume, Kazuto Hirata, Noriyuki Ohkura, Isao Tachibana, Yoshihiro Nishimura, Hisako Matsumoto, Yoshiaki Minakata, Masanori Yoshikawa, Masaki Fujimura
BACKGROUND AND OBJECTIVES: Assessment of the effects of long-term management on patient quality of life (QOL) would be extremely useful for determining asthma treatment strategies. However, no studies have evaluated QOL over an extended period of time. This study evaluated the changes in QOL, drug management and disease severity in the same asthma patients at an interval of approximately 9 years. METHODS: We re-surveyed asthma patients enrolled in a survey conducted in 2004 to evaluate the effects of approximately a decade of treatment on disease severity and QOL assessed by the Japanese Asthma Health Questionnaire (AHQ-JAPAN)...
January 2017: International Journal of Clinical Practice
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