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International Journal of Clinical Practice

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https://www.readbyqxmd.com/read/30011113/novel-non-invasive-biomarkers-diagnostic-of-acute-rejection-in-renal-transplant-recipients-a-systematic-review
#1
REVIEW
Faisal Jamshaid, Saied Froghi, Pierpaolo Di Cocco, Frank Jmf Dor
BACKGROUND AND OBJECTIVES: Acute rejection is a significant complication detrimental to kidney transplant function. Current accepted means of diagnosis is percutaneous renal biopsy, a costly and invasive procedure. There is an urgent need to detect and validate non-invasive biomarkers capable of replacing the biopsy. DESIGN, SETTING, PARTICIPANTS AND MEASUREMENTS: Comprehensive literature searches of Medline, EMBASE and Cochrane Central Register of Controlled Trials databases were performed...
July 16, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/30011112/second-cancers-in-hodgkin-s-lymphoma-long-term-survivals-a-60-year-single-institutional-experience-with-real-life-cohort-of-871-patients
#2
Katarina Petrakova, Jiri Vyskocil, Peter Grell, Ondrej Majek, Renata Soumarova, Jiri Novak, Petr Burkon, Zdenek Kral, Tomas Kazda, Rostislav Vyzula
BACKGROUND AND PURPOSE: Appropriate surveillance guidelines for patients after successful treatment of Hodgkin's lymphoma (HL) are needed to reduce mortality of iatrogenic secondary cancers (SC). This large single institutional retrospective study analyses the risk of SC in HL patients treated outside of clinical trials over past decades. MATERIAL AND METHODS: Consecutive series of HL patients were analysed with median follow-up 12 years. Standardised incidence ratio (SIR) and absolute excess risk (AER) were calculated for site-specific risk of SC...
July 16, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/30011111/truth-disclosure-on-prognosis-is-it-ethical-not-to-communicate-personalised-risk-of-death
#3
Magnolia Cardona, John Kellett, Ebony Lewis, Mikkel Brabrand, Danielle Ní Chróinín
Predicting risk of death based on personalised and objective clinical indicators is an improvement over intuition and clinical judgement. Risk assessment can benefit clinicians by improving prognostic certainty, and truth disclosure helps patients and families by preventing futile management. Some argue that consent should be obtained before a patient is given an estimate of their prognosis as disclosure of bad news can overburden patients. In this article, we argue that it is unethical not to use existing person-specific information to guide diagnosis and shared decision making on management in partnership with well-informed patients...
July 16, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/30011108/health-and-functional-status-health-events-use-of-healthcare-services-and-costs-associated-with-overactive-bladder-among-the-medically-complex-vulnerable-elderly-in-the-us
#4
Chien-Chia Chuang, Erru Yang, Kelly H Zou, Anna Araiza, Alan Wang, Xuemei Luo
AIMS: To assess the prevalence of overactive bladder (OAB) among medically complex vulnerable elderly (MCVE) patients in the United States and to compare health status measures, functional status, healthcare events, use of healthcare services and costs between MCVE patients with and without OAB. METHODS: Using the 2001-2010 Medicare Current Beneficiary Surveys, we defined the MCVE as those respondents who were ≥65 years old with scores ≥3 on the Vulnerable Elders Survey-13...
July 16, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29963733/effects-of-a-short-term-interval-aerobic-training-programme-with-active-recovery-bouts-iatp-r-on-cognitive-and-mental-health-functional-performance-and-quality-of-life-a-randomised-controlled-trial-in-sedentary-seniors
#5
Walid Bouaziz, Elise Schmitt, Thomas Vogel, François Lefebvre, Pierre-Marie Leprêtre, Georges Kaltenbach, Bernard Geny, Pierre-Olivier Lang
BACKGROUND: Interval aerobic training programme with active recovery bouts (IATP-R) has shown to improve tolerance to IATP among seniors. However, data concerning its benefits for seniors' health are still limited. PURPOSE: The purpose of this study was to examine the effects of IATP-R on seniors' health status. METHODS: Sedentary volunteers (n = 60, aged ≥70 years) were randomly assigned to either IATP-R or maintained sedentary lifestyle for 9...
July 2, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29920884/safety-and-effectiveness-of-hospital-in-the-home-and-outpatient-parenteral-antimicrobial-therapy-in-different-age-groups-a-systematic-review-of-observational-studies
#6
REVIEW
Shanthy Sriskandarajah, Jodie Hobbs, Elizabeth Roughead, Melissa Ryan, Karen Reynolds
OBJECTIVE: The aim of this study was .to systematically review the published literature of observational studies evaluating the safety and effectiveness of hospital in the home (HITH) and outpatient parenteral antimicrobial therapy (OPAT) in the general population, older people and children. STUDY DESIGN: The review included retrospective studies and prospective studies performed on HITH and OPAT within different age groups. Only the studies that analysed the safety and effectiveness of HITH and OPAT were included for review...
June 19, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29920883/psychometric-properties-of-hope-scales-a-systematic-review
#7
REVIEW
Dorit Redlich-Amirav, Levi J Ansell, Madisen Harrison, Kasara Lynn Norrena, Susan Armijo-Olivo
INTRODUCTION: Hope is recognised as an important factor in health, illness, and well-being. Many scales to measure hope have been developed and used in various disciplines, yet, their psychometric properties have not been systematically reviewed. AIM: To systematically review the psychometric properties of hope scales. DESIGN: Systematic review. METHODS: Four electronic databases were searched followed by a hand search...
June 19, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29920876/risk-of-psychiatric-disorders-in-irritable-bowel-syndrome-a-nationwide-population-based-cohort-study
#8
Hui-Wen Yeh, Wu-Chien Chien, Chi-Hsiang Chung, Je-Ming Hu, Nian-Sheng Tzeng
AIMS: This cohort study aimed to investigate the association between irritable bowel syndrome (IBS) and the risk of developing psychiatric disorders. METHODS: Utilizing the National Health Insurance Research Database (NHIRD) of Taiwan, IBS patients were identified and compared with age, sex, and index year-matched controls (1:3). RESULTS: Of the IBS subjects, 3934 in 22 356 (17.60%, or 1533.68 per 100 000 person-years) developed psychiatric disorders when compared with 6127 in 67 068 (9...
June 19, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29920875/interventions-to-improve-the-uptake-of-screening-across-a-range-of-conditions-in-ethnic-minority-groups-a-systematic-review
#9
REVIEW
Claire Kelly, Marinos Pericleous, Jane Hendy, Simon de Lusignan, Ayesha Ahmed, Tushna Vandrevala, Aftab Ala
BACKGROUND: Screening programmes are well established in cancer, and are now being implemented in other conditions. An effective screening programme leads to early disease detection and improved outcomes but its impact is dependent on the quality of the test and the proportion of the target population participating. A further consideration is that uptake of screening by minority groups is low. PURPOSE: To determine which interventions have successfully increased screening uptake amongst minorities...
June 19, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29920870/home-remedies-for-skin-tags-not-recommended
#10
Anca E Chiriac, Anca Chiriac, Adrian Naznean, Cristian Podoleanu, Simona Stolnicu
No abstract text is available yet for this article.
June 19, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29855115/a-retrospective-series-of-conditions-and-mortality-associated-with-extreme-hyperferritinaemia-in-adults
#11
Iona Thorne, Javier Stroud, Henry Penn
BACKGROUND: Serum ferritin is commonly used in the diagnosis of iron deficiency anaemia. However, extreme hyperferritinaemia suggests a significant illness, including the differential diagnosis of haemophagocytic lymphohistiocytosis (HLH), which is rare and associated with a high mortality, particularly if untreated. This series aims to identify the causes and associated mortality of severe hyperferritinaemia in patients seen at a teaching hospital in London, UK. METHOD: Demographic and medical data were collected for all patients over 18 years of age with extreme hyperferritinaemia (defined as serum ferritin levels of ≥4000 mcg/L)...
May 31, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29799148/melatonin-for-preventing-primary-headache-a-systematic-review
#12
REVIEW
Rafael Leite Pacheco, Carolina de Oliveira Cruz Latorraca, Anderson Adriano Leal Freitas da Costa, Ana Luiza Cabrera Martimbianco, Daniela Vianna Pachito, Rachel Riera
BACKGROUND: The aim of this study was to assess the effectiveness and safety of melatonin for primary headache. METHODS: This systematic review following the Cochrane Handbook for Systematic Reviews of Interventions recommendations and PRISMA Statement. RESULTS: Four randomized controlled trials were included (351 participants). According to the GRADE approach the quality of evidence was very low. The use of melatonin for migraine showed that (i) reduced the number of days with pain and the analgesic consumption when compared with placebo, (ii) no benefits on headache intensity, number of headache days and analgesics consumption when compared with amitriptyline, (iii) reduced the number of analgesic consumption, the attack frequency and the headache intensity when associated with propranolol plus nortriptyline vs placebo plus propranolol plus nortriptyline, and (iv) no difference for any of the interest outcomes when associated with propranolol plus nortriptyline vs sodium valproate plus propranolol plus nortriptyline...
May 24, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29790628/metabolic-syndrome-and-its-components-are-associated-with-increased-chronic-kidney-disease-risk-evidence-from-a-meta-analysis-on-11-109-003-participants-from-66-studies
#13
Shahab Alizadeh, Mahsa Ahmadi, Behnam Ghorbani Nejad, Abolghassem Djazayeri, Sakineh Shab-Bidar
BACKGROUND & AIMS: Observational studies examining the relationship between metabolic syndrome and the risk of chronic kidney disease (CKD) have reported inconclusive results. This meta-analysis was performed to resolve these controversies. METHODS: The MEDLINE, EMBASE, and PubMed databases were systematically searched from their inception until March 2016 to identify all relevant studies. Risk estimates and their corresponding 95% confidence intervals (CIs) for the associations of MetS and its components with CKD risk were extracted and pooled using a random-effects model...
May 23, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29691962/gastrointestinal-symptoms-in-children-primary-care-and-specialist-interface
#14
REVIEW
Valeria Dipasquale, Domenico Corica, Simone M C Gramaglia, Simona Valenti, Claudio Romano
AIMS: Gastrointestinal symptoms and diseases represent one of the major reasons for paediatricians' requests for specialist consultations and hospital admissions. One fourth of annual medical consultations for children younger than 6 years can be attributed to gastrointestinal symptoms. High-quality guidelines have been validated worldwide to provide clinical recommendations and support healthcare providers' practice. Nevertheless, overall compliance to standards of care is unsatisfactory, and children with gastrointestinal symptoms frequently undergo expensive, useless specialist consultations and laboratory evaluations...
April 24, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29691957/very-long-term-outcome-of-schizophrenia
#15
REVIEW
Jan Volavka, Jan Vevera
PURPOSE: The principal aim is to review recent data concerning the very long-term outcome of schizophrenia and schizophrenia spectrum disorders. We examine factors that influence outcome, including therapeutic interventions. METHOD: PubMed and Scopus databases were searched for papers published between 2008 and 2017 reporting on prospective studies of schizophrenia or schizophrenia spectrum with a follow-up period ≥5 years with adequate outcome information. Additional publications were found in reference lists and authors' reference libraries...
April 24, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29989292/summer-reading-medicine-psychoanalysis-and-the-zombie-apocalypse-in-comic-books
#16
EDITORIAL
Leslie Citrome
No abstract text is available yet for this article.
July 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29924469/enabling-high-value-care-in-common-paediatric-gastrointestinal-disorders
#17
EDITORIAL
J Rosen
No abstract text is available yet for this article.
June 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29924468/three-free-web-resources-for-clinicians-and-authors
#18
EDITORIAL
Leslie Citrome
No abstract text is available yet for this article.
June 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29924467/musculoskeletal-injections-analysis-of-healthcare-providers-understanding-of-indications-risks-and-rehabilitation
#19
LETTER
Baljinder Singh Dhinsa, Dilip Pillai, Abhinav Gulihar, Tony Kochhar
No abstract text is available yet for this article.
June 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29924466/degludec-is-effective-and-safe-in-real-life-treatment-for-patients-with-type-2-diabetes-mellitus-and-chronic-kidney-disease-stage-3b
#20
LETTER
Maria Dolores Garcia de Lucas, Julian Olalla Sierra, Beatriz Aviles Bueno
No abstract text is available yet for this article.
June 2018: International Journal of Clinical Practice
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