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AIDS and Behavior

Jeffrey I Campbell, Nir Eyal, Angella Musiimenta, Bridget Burns, Sylvia Natukunda, Nicholas Musinguzi, Jessica E Haberer
Many new technologies monitor patients' and study participants' medical adherence. Some have cautioned that these devices transgress personal autonomy and ethics. But do they? This qualitative study explored how Ugandan study participants perceive the effect of electronic monitoring of their adherence to antiretroviral therapy (ART) on their freedoms to be non-adherent and pursue other activities that monitoring may inadvertently expose. Between August 2014 and June 2015, we interviewed 60 Ugandans living with HIV and enrolled in the Uganda AIDS Rural Treatment Outcomes (UARTO) study, a longitudinal, observational study involving electronic adherence monitors (EAMs) to assess ART adherence...
June 20, 2018: AIDS and Behavior
Deborah L Jones, Violeta J Rodriguez, Lissa N Mandell, Tae Kyoung Lee, Stephen M Weiss, Karl Peltzer
South African guidelines for prevention-of-mother-to-child-transmission (PMTCT) of HIV emphasize exclusive breastfeeding (EBF). This study examined the impact of a PMTCT intervention and male involvement on EBF. In a two-phase cluster-randomized trial, rural South African community health centers were randomized to offer HIV-infected pregnant women PMTCT standard of care plus either: a behavioral PMTCT intervention, or a time-equivalent attention-control condition. Phase 1 women had non-participating male partners; Phase 2 women had participating partners...
June 20, 2018: AIDS and Behavior
Deborah B Brickley, Christina P Lindan
No abstract text is available yet for this article.
June 18, 2018: AIDS and Behavior
Fiona Scorgie, Jonathan Stadler, Deborah Baron, Susan Ju, Tshepiso Ikaneng, Zonke Mabude, Sylvia Makgopa, Matshidiso A Malefo, Kgahlisho N Manenzhe, Thulani Mazibuko, Hilda Ntjana, Busi Nkala, Thesla Palanee-Phillips, Glenda Gray, Helen Rees, Sinead Delany-Moretlwe
The FACTS 001 trial found that vaginal pre- and post-coital application of 1% tenofovir gel did not prevent HIV-1 infection amongst young South African women. The trial included a multi-faceted approach to adherence support and collected objective and self-reported adherence measures. Using qualitative data collected from a random sub-set of FACTS 001 participants (135 in-depth interviews at product discontinuation and 13 focus group discussions at dissemination of trial results), we explore the importance of 'place' and 'timing' in shaping acts of sexual intimacy and product adherence...
June 16, 2018: AIDS and Behavior
Valerie A Earnshaw, Rachel C Kidman, Avy Violari
A growing population of youth who acquired HIV from their mothers are surviving into adulthood. This group is unique in that they experience both internalized stigma (due to their HIV status) and associative stigma (due to their mothers' HIV status). Results of a cross-sectional survey of 250 perinatally HIV-infected South African youth suggests that internalized stigma is associated with greater risk of depression, and associative stigma is associated with greater risk of depression and substance use problems...
June 16, 2018: AIDS and Behavior
María Dolores Gil-Llario, Vicente Morell-Mengual, Cristina Giménez-García, Pedro Salmerón-Sánchez, Rafael Ballester-Arnal
Sexual Sensation Seeking has been identified as a main predictor of unsafe sex that particularly affects LGB people. This study adapts and validates the Sexual Sensation Seeking Scale to Spanish LGB people. For this purpose, we tested the factor structure in 1237 people, ranged from 17 to 60 years old, 880 self-defined as homosexuals and 357 as bisexuals. The results support the appropriateness of this scale for Spanish LGB people and determine two factors, explaining the 49.91% of variance: "physical sensations attraction" and "sexual experiences"...
June 7, 2018: AIDS and Behavior
Tabor E Flickinger, Claire DeBolt, Alice Xie, Alison Kosmacki, Marika Grabowski, Ava Lena Waldman, George Reynolds, Mark Conaway, Wendy F Cohn, Karen Ingersoll, Rebecca Dillingham
Stigma has negative consequences for quality of life and HIV care outcomes. PositiveLinks is a mobile health intervention that includes a secure anonymous community message board (CMB). We investigated discussion of stigma and changes in stigma scores. Of 77 participants in our pilot, 63% were male, 49% Black, and 72% had incomes below the federal poverty level. Twenty-one percent of CMB posts (394/1834) contained stigma-related content including negative (experiencing stigma) and positive (overcoming stigma) posts addressing intrapersonal and interpersonal stigma...
June 7, 2018: AIDS and Behavior
Ayden I Scheim, Ekaterina Nosova, Rod Knight, Kanna Hayashi, Thomas Kerr
Few data on HIV incidence among men who have sex with men and inject drugs (MSM-PWID) are available. Drawing on a prospective cohort in Vancouver, Canada, we examined the relationship between MSM status and HIV incidence among PWID using Kaplan-Meier analyses and extended Cox regression. Data were collected from 1996 to 2014 and analyzed in 2017. Of 1131 HIV-negative male PWID, 8.6% (n = 97) reported sex with men over the study period. MSM status was crudely associated with HIV incidence [Hazard Ratio (HR) = 1...
June 6, 2018: AIDS and Behavior
Douglas Bruce, José A Bauermeister, Shoshana Y Kahana, Eduardo Mendoza, M Isabel Fernández
Sexual transmission risk occurs in the context of serodiscordant condomless anal intercourse (CAI) where the seropositive partner is virologically detectable (VL+) and/or seronegative partner is not on PrEP. We analyzed correlates of serodiscordant CAI among 688 VL+ young men who have sex with men (YMSM). In multivariable analyses, serodiscordant CAI was associated with a receiving a HIV diagnosis in the past 6 months, greater depressive symptoms, and cocaine use during the past 90 days. Although HIV+ YMSM currently experience disparities across the continuum of care, those new to care may need support adopting risk reduction strategies with their sexual partners...
June 6, 2018: AIDS and Behavior
Rogério M Pinto, Kathryn R Berringer, Rita Melendez, Okeoma Mmeje
There are many challenges to accessing PrEP and thus low uptake in the United States. This review (2007-2017) of PrEP implementation identified barriers to PrEP and interventions to match those barriers. The final set of articles (n = 47) included content on cognitive aspects of HIV service providers and individuals at risk for infection, reviews, and case studies. Cognitive barriers and interventions regarding patients and providers included knowledge, attitudes, and beliefs about PrEP. The "purview paradox" was identified as a key barrier-HIV specialists often do not see HIV-negative patients, while primary care physicians, who often see uninfected patients, are not trained to provide PrEP...
June 5, 2018: AIDS and Behavior
Anna LeViere, Jenna Donovan, Aimee Wilkin, Jennifer Keller, Heather Parnell, Lynne Sampson, Cynthia L Gay, Evelyn Byrd Quinlivan
Social networks can be leveraged to identify undiagnosed HIV-infected individuals. The NC-LINK clinic-based testing initiative utilized these networks to achieve a 5% (95% CI 1.1-8.9%) positivity rate by providing free HIV testing to anyone who accompanied an HIV-infected patient to their clinic appointment. During 2013-2015, 120 individuals were tested at two clinics (N > 1000 patients each) in North Carolina, with 5 new and 6 total positive results. Of these, three linked to care within 30 days and all within 365 days...
June 5, 2018: AIDS and Behavior
Bonnie Robin Tran, Anthony Davis, Stanley I Ito, Faustin Matchere, Elizabeth Reader, Victor Nkhoma, Michael Grillo, Alfred Chitsa Banda
Substance abuse is a public health priority in the context of the HIV epidemic, especially in military communities. This cross-sectional study quantified alcohol and cannabis use in the Malawi Defence Force and investigated its associations with condom use, transactional sex, multiple sexual partners, and sexual violence. Participants were 944 male and female service members ≥ 18 years old. Data were collected in 2013 using a computer-assisted self-interview. Twenty-four percent of men and women screened positive for hazardous and harmful drinking [Alcohol Use Disorders Identification Test (AUDIT) score ≥ 8]...
June 5, 2018: AIDS and Behavior
D Joseph Davey, S West, V Umutoni, S Taleghani, H Klausner, E Farley, R Shah, S Madni, S Orewa, V Kottamasu, V Rice, Z Robbin, K M Wall
We conducted a systematic review of safer conception strategies (SCS) for HIV-affected couples in sub-Saharan Africa to inform evidence-based safer conception interventions. Following PRISMA guidelines, we searched fifteen electronic databases using the following inclusion criteria: SCS research in HIV-affected couples; published after 2007; in sub-Saharan Africa; primary research; peer-reviewed; and addressed a primary topic of interest (SCS availability, feasibility, and acceptability, and/or education and promotion)...
June 4, 2018: AIDS and Behavior
Audrey Harkness, Sierra A Bainter, Conall O'Cleirigh, Noelle A Mendez, Kenneth H Mayer, Steven A Safren
This study examined longitudinally the additive effect of syndemics, or co-occurring psychosocial problems, on antiretroviral treatment (ART) non-adherence among 390 HIV-positive sexual minority men. Participants completed measures of ART adherence (reduced to a non-adherence score using exploratory factor analysis) and six syndemic conditions. We employed multilevel modeling with the number of syndemics as a longitudinal predictor of non-adherence, and logistic regression with baseline syndemics predicting follow up viral load...
June 2, 2018: AIDS and Behavior
Jordan M Sang, Derrick D Matthews, Steven P Meanley, Lisa A Eaton, Ron D Stall
The deleterious effects of HIV stigma on HIV+ Black MSM care continuum outcomes have been well-documented. How HIV stigma shapes HIV prevention for HIV- persons in this community is poorly understood. We sought to test the relationship of HIV stigma with HIV- Black MSM on HIV testing, pre-exposure prophylaxis (PrEP) awareness, and PrEP use. We recruited 772 participants at Black Pride events across five US cities in 2016. Multivariable logistic regression models assessed the association of external HIV stigma on prevention outcomes adjusting for sociodemographic variables...
June 2, 2018: AIDS and Behavior
Beryl A Koblin, DaShawn Usher, Vijay Nandi, Hong-Van Tieu, Eddie Bravo, Debbie Lucy, London Miles, Geneva Ortiz, Marcia J Kindlon, Donna M Parisi, Victoria Frye
Post-exposure prophylaxis (PEP) is a cost-effective, but underused HIV prevention strategy. PEP awareness, knowledge, access, and usage was assessed among young men of color who have sex with men (YMSMOC; n = 177), transgender women (TW; n = 182), and cisgender women of color (CWOC; n = 170) in New York City. 59% were aware of PEP: 80% among YMSMOC, 63% among TW and 34% among CWOC (p < 0.001). 13% had ever used PEP. PEP awareness was higher among YMSMOC with a recent HIV test and lower among those with ≥ 4 partners...
June 1, 2018: AIDS and Behavior
Sylvia Kusemererwa, Andrew Abaasa, Martin Onyango, Annalene M Nel, Michelle Isaacs, Gershim Asiki
Contraceptive preferences of women at risk for HIV acquisition are not well documented. We report on contraceptive choices among women residing in small townships in southwestern Uganda. This was part of preparatory efforts for recruitment into the Ring Study, a phase 3 microbicide trial, between July 2013 and October 2014. Clinicians provided contraceptives per a woman's choice. HIV testing and screening for other sexually transmitted infections were done at first contact and at screening for the trial. Contraceptive choice was summarized by demographics and regression analysis to show factors associated with use of the injectable method...
May 31, 2018: AIDS and Behavior
Jacklyn D Babowitch, Alan Z Sheinfil, Sarah E Woolf-King, Peter A Vanable, Shannon M Sweeney
The original version of this article unfortunately contained a mistake in Fig. 1. The figure was incorrectly presented with the results of an additional path model for forgotten antiretroviral therapy (ART) doses that was dropped from the primary analyses.
May 31, 2018: AIDS and Behavior
Brice Faraut, Alexandre Malmartel, Jade Ghosn, Martin Duracinsky, Damien Leger, Sophie Grabar, Jean-Paul Viard
Short and long sleep durations have been associated with inflammation and chronic diseases. To study the association between sleep duration/quality and HIV disease severity, a cross-sectional study was conducted in patients living with HIV (PLWHs) using self-administered questionnaires assessing total sleep time, insomnia (ICSD-3 criteria), and poor sleep quality (PSQI > 5). Multivariable logistic regression identified the factors associated with sleep disorders and with HIV features. 640 Parisian ambulatory PLWHs were included...
May 31, 2018: AIDS and Behavior
Laura Gauer Bermudez, Fred M Ssewamala, Torsten B Neilands, Lily Lu, Larissa Jennings, Gertrude Nakigozi, Claude A Mellins, Mary McKay, Miriam Mukasa
To assess the effect of a savings-led economic empowerment intervention on viral suppression among adolescents living with HIV. Using data from Suubi + Adherence, a longitudinal, cluster randomized trial in southern Uganda (2012-2017), we examine the effect of the intervention on HIV RNA viral load, dichotomized between undetectable (< 40 copies/ml) and detectable (≥ 40 copies/ml). Cluster-adjusted comparisons of means and proportions were used to descriptively analyze changes in viral load between study arms while multi-level modelling was used to estimate treatment efficacy after adjusting for fixed and random effects...
May 30, 2018: AIDS and Behavior
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